Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_50376 | 1046 | 21.79 | Mlig455_021483 | Neo: - Age: logFC(26M/2M)=0.656 Regeneration-upregulated R5: 3.223 Regeneration-enriched R5: 3.223 |
HSPG2 | Mlig455_021483 {REF} {Length: 7204} {Pfam: Immunoglobulin domain [PF13927.8, score=105.9]; Immunoglobulin I-set domain [PF07679.18, score=70.3]; Immunoglobulin V-set domain [PF07686.19, score=68.2]; Immunoglobulin domain [PF00047.27, score=60.3]; Immunoglobulin domain [PF13895.8, score=58.0]; Laminin B (Domain IV) [PF00052.20, score=53.8]; Low-density lipoprotein receptor domain class A [PF00057.20, score=29.9]; Laminin EGF domain [PF00053.26, score=22.8]} {Human: ENSG00000142798, HSPG2, heparan sulfate proteoglycan 2, [Score=122, Expect=4e-27]} {Mouse: ENSMUSG00000028763, Hspg2, perlecan (heparan sulfate proteoglycan 2), [Score=111, Expect=7e-24]} {Dmel: FBgn0284408, trol, terribly reduced optic lobes, [Score=109, Expect=2e-23]} {Celegans: WBGene00006787, unc-52, Basement membrane proteoglycan, [Score=157, Expect=6e-38]} {Smed: dd_Smed_v6_6915_0_1, dd_Smed_v6_6915_0_1, [Score=154, Expect=3e-37]} {RNA1509_3385} {RNA1310_393.1} {RNA815_120.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 2.593 | 4.599 | 0.02202 | 0.40452 | |
RegionR2 | 0.48 | 4.599 | 0.46588 | 0.85195 | |
RegionR3 | -0.536 | 4.599 | 0.39684 | 0.92674 | |
RegionR4 | 0.752 | 4.599 | 0.26306 | 0.56640 | |
RegionR5 | -1.677 | 4.599 | 0.01128 | 0.06292 | |
RegionR6 | -0.132 | 4.599 | 0.84106 | 1.00000 | |
RegionR7 | 0.542 | 4.599 | 0.44432 | 1.00000 | |
RegionR8 | -2.022 | 4.599 | 0.14780 | 0.70035 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.129 | 4.599 | 0.91545 | 1.00000 | |
RegenerationR2 | 0.817 | 4.599 | 0.16597 | 0.60343 | |
RegenerationR3 | 1.914 | 4.599 | 0.00426 | 0.11814 | |
RegenerationR4 | 1.007 | 4.599 | 0.13022 | 0.54587 | |
RegenerationR5 | 3.223 | 4.599 | 0.00000 | 0.00096 | Specific for R5: 3.223 |
RegenerationR6 | 2.44 | 4.599 | 0.00024 | 0.01491 | |
RegenerationBL | 1.452 | 4.599 | 0.05555 | 0.27290 | |
RegenerationTP | 1.511 | 4.599 | 0.10724 | 0.50580 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_50376 | 1046 | 21.79 | Mlig455_021483 | Neo: - Age: logFC(26M/2M)=0.656 Regeneration-upregulated R5: 3.223 Regeneration-enriched R5: 3.223 |
HSPG2 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_021483 {REF} {Length: 7204} {Pfam: Immunoglobulin domain [PF13927.8, score=105.9]; Immunoglobulin I-set domain [PF07679.18, score=70.3]; Immunoglobulin V-set domain [PF07686.19, score=68.2]; Immunoglobulin domain [PF00047.27, score=60.3]; Immunoglobulin domain [PF13895.8, score=58.0]; Laminin B (Domain IV) [PF00052.20, score=53.8]; Low-density lipoprotein receptor domain class A [PF00057.20, score=29.9]; Laminin EGF domain [PF00053.26, score=22.8]} {Human: ENSG00000142798, HSPG2, heparan sulfate proteoglycan 2, [Score=122, Expect=4e-27]} {Mouse: ENSMUSG00000028763, Hspg2, perlecan (heparan sulfate proteoglycan 2), [Score=111, Expect=7e-24]} {Dmel: FBgn0284408, trol, terribly reduced optic lobes, [Score=109, Expect=2e-23]} {Celegans: WBGene00006787, unc-52, Basement membrane proteoglycan, [Score=157, Expect=6e-38]} {Smed: dd_Smed_v6_6915_0_1, dd_Smed_v6_6915_0_1, [Score=154, Expect=3e-37]} {RNA1509_3385} {RNA1310_393.1} {RNA815_120.1} |
2. | MligTC455_50377 | 5461 | 113.78 | Mlig455_062017, Mlig455_067368 | Neo: - Age: - Regeneration-upregulated R5: 2.274 Regeneration-enriched R5: 2.274 |
HSPG2 | 4.362 | 0.731 | 0.889 | - | 0.915 | 0.868 | 0.959 | Mlig455_062017 {REF} {Length: 7578} {Pfam: Immunoglobulin domain [PF13927.8, score=145.6]; Immunoglobulin I-set domain [PF07679.18, score=103.6]; Immunoglobulin domain [PF00047.27, score=79.6]; Immunoglobulin V-set domain [PF07686.19, score=76.3]; Immunoglobulin domain [PF13895.8, score=60.3]; Laminin B (Domain IV) [PF00052.20, score=53.5]; Low-density lipoprotein receptor domain class A [PF00057.20, score=49.7]; Laminin EGF domain [PF00053.26, score=22.5]} {Human: ENSG00000142798, HSPG2, heparan sulfate proteoglycan 2, [Score=147, Expect=3e-34]} {Mouse: ENSMUSG00000028763, Hspg2, perlecan (heparan sulfate proteoglycan 2), [Score=143, Expect=2e-33]} {Dmel: FBgn0284408, trol, terribly reduced optic lobes, [Score=122, Expect=3e-27]} {Celegans: WBGene00006787, unc-52, Basement membrane proteoglycan, [RH, Score=178, Expect=2e-44]} {Smed: dd_Smed_v6_8356_0_1, dd_Smed_v6_8356_0_1, [RH, Score=177, Expect=1e-44]} {RNA1509_550} {RNA1310_393.1} {RNA815_120.1} Mlig455_067368 {REF} {Length: 7578} {Pfam: Immunoglobulin domain [PF13927.8, score=145.6]; Immunoglobulin I-set domain [PF07679.18, score=103.8]; Immunoglobulin domain [PF00047.27, score=80.2]; Immunoglobulin V-set domain [PF07686.19, score=76.9]; Immunoglobulin domain [PF13895.8, score=58.8]; Laminin B (Domain IV) [PF00052.20, score=53.7]; Low-density lipoprotein receptor domain class A [PF00057.20, score=49.7]; Laminin EGF domain [PF00053.26, score=22.5]} {Human: ENSG00000142798, HSPG2, heparan sulfate proteoglycan 2, [Score=147, Expect=1e-34]} {Mouse: ENSMUSG00000028763, Hspg2, perlecan (heparan sulfate proteoglycan 2), [Score=144, Expect=1e-33]} {Dmel: FBgn0284408, trol, terribly reduced optic lobes, [Score=126, Expect=2e-28]} {Celegans: WBGene00006787, unc-52, Basement membrane proteoglycan, [RH, Score=177, Expect=4e-44]} {Smed: dd_Smed_v6_8356_0_1, dd_Smed_v6_8356_0_1, [RH, Score=177, Expect=1e-44]} {RNA1509_37123, RNA1509_550} {RNA1310_393.1, RNA1509_37123} {RNA1509_37123, RNA815_120.1} |
3. | MligTC455_30395 | 108 | 2.25 | Mlig455_070650 | Neo: - |
ALDH18A1 | 1.675 | - | - | - | 0.963 | 0.712 | - | Mlig455_070650 {REF} {Length: 3857} {Pfam: Amino acid kinase family [PF00696.30, score=138.7]; Aldehyde dehydrogenase family [PF00171.24, score=57.0]} {Human: ENSG00000059573, ALDH18A1, aldehyde dehydrogenase 18 family member A1, [RH, Score=852, Expect=0.0]} {Mouse: ENSMUSG00000025007, Aldh18a1, aldehyde dehydrogenase 18 family, member A1, [RH, Score=857, Expect=0.0]} {Dmel: FBgn0037146, CG7470, [RH, Score=815, Expect=0.0]} {Celegans: WBGene00011938, alh-13, Probable delta-1-pyrroline-5-carboxylate synthase Glutamate 5-kinase Gamma-glutamyl phosphate reductase, [RH, Score=811, Expect=0.0]} {Smed: dd_Smed_v6_1060_0_1, dd_Smed_v6_1060_0_1, [RH, Score=916, Expect=0.0]} {RNA1509_1671} {RNA1310_2413} {RNA815_1917} |
4. | MligTC455_42758 | 1058 | 22.04 | Mlig455_003527, Mlig455_015536 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.687 Regeneration-downregulated BL: -8.367 Regeneration-depleted BL: -8.367 |
ANGPTL1 | 0.975 | - | - | 0.975 | - | - | - | Mlig455_003527 {REF} {Length: 1416} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=123.1]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=114, Expect=1e-27]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=112, Expect=6e-27]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=115, Expect=3e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=112, Expect=3e-27]; ENSMUSG00000026938, Fcna, ficolin A, [Score=110, Expect=3e-27]} {Dmel: FBgn0033312, CG8642, [Score=98.2, Expect=2e-22]} {Celegans: WBGene00020516, T15B7.1, [Score=68.2, Expect=1e-12]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=48.1, Expect=4e-07]} {RNA1509_24863} {RNA1310_24297.1} {RNA815_9254} Mlig455_015536 {REF} {Length: 1416} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=124.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=114, Expect=1e-27]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=112, Expect=5e-27]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=115, Expect=3e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=112, Expect=2e-27]; ENSMUSG00000026938, Fcna, ficolin A, [Score=111, Expect=1e-27]} {Dmel: FBgn0033312, CG8642, [Score=98.6, Expect=1e-22]} {Celegans: WBGene00020516, T15B7.1, [Score=69.7, Expect=4e-13]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=48.1, Expect=4e-07]} {RNA1509_24863} {RNA1310_24297.1, RNA1509_24863} {RNA1509_24863, RNA815_9254} |
5. | MligTC455_26999 | 330 | 6.88 | Mlig455_037719, Mlig455_037789 | Neo: - Age: - |
RBM12B | 0.97 | - | - | 0.970 | - | - | - | Mlig455_037719 {REF} {Length: 3624} {Pfam: Mitochondrial distribution and morphology protein 10 [PF12519.10, score=19.6]} {Human: ENSG00000183808, RBM12B, RNA binding motif protein 12B, [Score=58.9, Expect=4e-08]} {RNA1509_40809} {RNA1310_8203} {RNA815_13132} Mlig455_037789 {REF} {Length: 3262} {Human: ENSG00000183808, RBM12B, RNA binding motif protein 12B, [Score=61.2, Expect=7e-09]} {RNA1310_8203} {RNA815_13132} |
6. | MligTC455_27045 | 227 | 4.73 | Mlig455_018647 | Neo: - Age: - |
GNAO1 | 0.965 | - | - | - | 0.965 | - | - | Mlig455_018647 {REF} {Length: 2347} {TRANSSPLICED} {Pfam: G-protein alpha subunit [PF00503.22, score=412.0]; ADP-ribosylation factor family [PF00025.23, score=62.0]; Gtr1/RagA G protein conserved region [PF04670.14, score=26.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=18.8]} {Human: ENSG00000087258, GNAO1, G protein subunit alpha o1, [RH, Score=620, Expect=0.0]} {Mouse: ENSMUSG00000031748, Gnao1, guanine nucleotide binding protein, alpha O, [RH, Score=616, Expect=0.0]} {Dmel: FBgn0001122, Galphao, G protein alpha o subunit, [RH, Score=645, Expect=0.0]} {Celegans: WBGene00001648, goa-1, Guanine nucleotide-binding protein G(o) subunit alpha, [RH, Score=644, Expect=0.0]} {Smed: dd_Smed_v6_1656_0_3, dd_Smed_v6_1656_0_3, [RH, Score=669, Expect=0.0]} {RNA1509_29905, RNA1509_33640, RNA1509_6513} {RNA1310_20987.1, RNA1509_29905, RNA1509_33640, RNA1509_6513} {RNA1509_29905, RNA1509_33640, RNA1509_6513, RNA815_1682.2} |
7. | MligTC455_46340 | 259 | 5.4 | Mlig455_049774 | Neo: - Age: - Region-enriched R1: 5.320/0.00375 |
0.963 | - | - | 0.963 | - | - | - | Mlig455_049774 {REF} {Length: 1638} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=40.1]; Ankyrin repeats (many copies) [PF13637.8, score=27.8]; Ankyrin repeats (many copies) [PF13857.8, score=24.8]; Ankyrin repeat [PF13606.8, score=19.1]} {Smed: dd_Smed_v6_29956_0_1, dd_Smed_v6_29956_0_1, [RH, Score=75.9, Expect=1e-14]} {RNA1509_39973} {RNA1310_21889} {RNA815_13094} | |
8. | MligTC455_52960 | 2270 | 47.28 | Mlig455_013223, Mlig455_013250, Mlig455_013318 | Neo: - Age: - |
SLC38A10 | 0.96 | - | - | 0.960 | - | - | - | Mlig455_013223 {REF} {Length: 1995} {TRANSSPLICED} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=163.9]; Tryptophan/tyrosine permease family [PF03222.15, score=28.2]} {Human: ENSG00000157637, SLC38A10, solute carrier family 38 member 10, [Score=244, Expect=1e-71]} {Mouse: ENSMUSG00000061306, Slc38a10, solute carrier family 38, member 10, [Score=247, Expect=3e-71]} {Dmel: FBgn0050394, CG30394, [Score=213, Expect=2e-60]} {Celegans: WBGene00021765, Y51F10.4, [Score=180, Expect=8e-50]} {Smed: dd_Smed_v6_11525_0_1, dd_Smed_v6_11525_0_1, [Score=203, Expect=4e-60]} {RNA1509_15934} {RNA1310_24099, RNA1509_15934} {RNA1509_15934, RNA815_5073.1} Mlig455_013250 {REF} {Length: 1771} {TRANSSPLICED} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=88.7]} {Human: ENSG00000157637, SLC38A10, solute carrier family 38 member 10, [Score=126, Expect=1e-30]} {Mouse: ENSMUSG00000061306, Slc38a10, solute carrier family 38, member 10, [Score=130, Expect=3e-32]} {Dmel: FBgn0050394, CG30394, [Score=133, Expect=2e-33]} {Celegans: WBGene00021765, Y51F10.4, [Score=98.2, Expect=8e-22]} {Smed: dd_Smed_v6_11525_0_1, dd_Smed_v6_11525_0_1, [Score=117, Expect=6e-29]} {RNA1509_15934} {RNA1310_28648.1} {RNA815_5073.1} Mlig455_013318 {REF} {Length: 1970} {TRANSSPLICED} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=164.1]; Tryptophan/tyrosine permease family [PF03222.15, score=28.7]} {Human: ENSG00000157637, SLC38A10, solute carrier family 38 member 10, [Score=244, Expect=9e-72]} {Mouse: ENSMUSG00000061306, Slc38a10, solute carrier family 38, member 10, [Score=246, Expect=4e-71]} {Dmel: FBgn0050394, CG30394, [Score=213, Expect=2e-60]} {Celegans: WBGene00021765, Y51F10.4, [Score=180, Expect=7e-50]} {Smed: dd_Smed_v6_11525_0_1, dd_Smed_v6_11525_0_1, [Score=204, Expect=3e-60]} {RNA1509_15934} {RNA1310_24099} {RNA815_5073.1} |
9. | MligTC455_42485 | 159 | 3.31 | Mlig455_046457 | Neo: - Age: - |
0.957 | - | - | 0.957 | - | - | - | Mlig455_046457 {REF} {Length: 846} {RNA1310_40237.1} {RNA815_18246} | |
10. | MligTC455_30821 | 152 | 3.16 | Mlig455_037011 | Neo: - Age: logFC(26M/2M)=0.420 Region-enriched R4: 2.497/0.04454 |
0.956 | - | - | - | 0.956 | - | - | Mlig455_037011 {REF} {Length: 2435} {RNA1509_41127} {RNA1310_36587.1} {RNA815_7423} | |
11. | MligTC455_45521 | 1185 | 24.68 | Mlig455_029423 | Neo: - Age: Down-Down-Up |
ANKRD50 | 0.955 | - | - | - | 0.955 | - | - | Mlig455_029423 {REF} {Length: 3455} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=255.6]; Protein kinase domain [PF00069.27, score=194.6]; Ankyrin repeats (many copies) [PF13637.8, score=186.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=149.5]; Ankyrin repeat [PF13606.8, score=132.1]; Ankyrin repeats (many copies) [PF13857.8, score=122.5]; Ankyrin repeat [PF00023.32, score=103.8]; ABC1 atypical kinase-like domain [PF03109.18, score=30.9]; Kinase-like [PF14531.8, score=30.6]; Fungal protein kinase [PF17667.3, score=27.6]; Phosphotransferase enzyme family [PF01636.25, score=20.0]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=173, Expect=1e-43]; ENSG00000151150, ANK3, ankyrin 3, [Score=172, Expect=3e-43]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=174, Expect=4e-44]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=172, Expect=2e-43]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=170, Expect=6e-43]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=158, Expect=2e-39]} {Smed: dd_Smed_v6_11663_0_4, dd_Smed_v6_11663_0_4, [Score=202, Expect=7e-55]} {RNA1509_26915, RNA1509_27995, RNA1509_4407} {RNA1310_2580.1, RNA1509_26915, RNA1509_27995} {RNA1509_26915, RNA1509_27995, RNA815_1154.1} |
12. | MligTC455_47393 | 241 | 5.03 | Mlig455_008718, Mlig455_063579 | Neo: - Age: Down-Up-Down Region-enriched R2: 3.683/0.00849 |
CALM2 | 0.954 | - | - | 0.954 | - | - | - | Mlig455_008718 {REF} {Length: 1727} {Pfam: EF hand [PF00036.34, score=99.3]; EF-hand domain pair [PF13499.8, score=95.1]; EF-hand domain [PF13405.8, score=86.1]; EF-hand domain pair [PF13833.8, score=76.8]; EF hand [PF13202.8, score=75.3]; EF-hand domain [PF14658.8, score=46.0]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.9]; EF-hand domain [PF08976.13, score=23.4]; Uncharacterised protein family (UPF0154) [PF03672.15, score=18.7]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=108, Expect=4e-30]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=4e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=4e-30]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-30]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=108, Expect=2e-30]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=1e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-30]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-30]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=114, Expect=8e-33]} {RNA1310_33847.1} {RNA815_17211} Mlig455_063579 {REF} {Length: 2562} {Pfam: EF hand [PF00036.34, score=95.8]; EF-hand domain pair [PF13499.8, score=92.8]; EF-hand domain [PF13405.8, score=82.9]; EF-hand domain pair [PF13833.8, score=74.4]; EF hand [PF13202.8, score=72.2]; EF-hand domain [PF14658.8, score=43.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.6]; EF-hand domain [PF08976.13, score=21.4]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=111, Expect=7e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=3e-29]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=3e-29]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=111, Expect=7e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-29]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-29]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=9e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-29]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-29]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=111, Expect=9e-31]} {RNA1310_12431.1} {RNA815_17211} |
13. | MligTC455_30735 | 56 | 1.16 | Mlig455_020871, Mlig455_020917 | Neo: - |
0.951 | - | - | - | 0.951 | - | - | Mlig455_020871 {REF} {Length: 2556} {RNA1509_14810} {RNA1310_13569.1} {RNA815_6042.1} Mlig455_020917 {REF} {Length: 2926} {RNA1509_14810} {RNA1310_13569.1} {RNA815_6042.1} |