M. lignano Tomo-Seq
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Results for MligTC455_51333

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_51333 12367 257.64 Mlig455_060286, Mlig455_066866

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=2.615

Region-enriched R3: 2.147/0.00011

Regeneration-enriched TP: 4.057
Regeneration-enriched R5: 3.389
Regeneration-enriched R4: 2.564
Regeneration-enriched BL: 2.278

Mlig455_060286 {REF} {Length: 776} {RNA1509_10952, RNA1509_39943, RNA1509_7962} {RNA1310_39900.1, RNA1509_10952, RNA1509_39943, RNA1509_7962} {RNA1509_10952, RNA1509_39943, RNA1509_7962, RNA815_26830}

Mlig455_066866 {REF} {Length: 778} {RNA1509_7962} {RNA1310_39900.1} {RNA815_26830}

Cumulative graph for MligTC455_51333

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.688 7.979 0.43453 1.00000
RegionR2 -0.229 7.979 0.70060 1.00000
RegionR3 2.147 7.979 0.00000 0.00011
RegionR4 1.268 7.979 0.02043 0.10378
RegionR5 0.483 7.979 0.30709 0.64462
RegionR6 0.946 7.979 0.05168 0.42659
RegionR7 -1.185 7.979 0.04608 0.41337
RegionR8 -2.742 7.979 0.00060 0.03244

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 3.909 7.979 0.00001 0.01295
RegenerationR2 2.479 7.979 0.00010 0.01192
RegenerationR3 1.954 7.979 0.00196 0.07574
RegenerationR4 2.564 7.979 0.00010 0.00676
RegenerationR5 3.389 7.979 0.00000 0.00037
RegenerationR6 1.624 7.979 0.01090 0.12897
RegenerationBL 2.278 7.979 0.00005 0.00276
RegenerationTP 4.057 7.979 0.00000 0.00000


Genes with expression patterns similar to MligTC455_51333

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_51333 12367 257.64 Mlig455_060286, Mlig455_066866

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=2.615

Region-enriched R3: 2.147/0.00011

Regeneration-enriched TP: 4.057
Regeneration-enriched R5: 3.389
Regeneration-enriched R4: 2.564
Regeneration-enriched BL: 2.278

 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_060286 {REF} {Length: 776} {RNA1509_10952, RNA1509_39943, RNA1509_7962} {RNA1310_39900.1, RNA1509_10952, RNA1509_39943, RNA1509_7962} {RNA1509_10952, RNA1509_39943, RNA1509_7962, RNA815_26830}

Mlig455_066866 {REF} {Length: 778} {RNA1509_7962} {RNA1310_39900.1} {RNA815_26830}
2. MligTC455_51332 7672 159.83 Mlig455_066802

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.266

Region-enriched R3: 2.076/0.00062

Regeneration-enriched TP: 3.879
Regeneration-enriched R5: 3.442
Regeneration-enriched R4: 2.740
Regeneration-enriched BL: 2.235

 5.488 0.771 0.867 0.948 0.995 0.967 0.940 Mlig455_066802 {REF} {Length: 1687} {RNA1509_7962} {RNA1310_39900.1} {RNA815_26830}
3. MligTC455_43893 18586 387.21 Mlig455_050275

Neo: -

Age: logFC(26M/2M)=0.702

Region-enriched R3: 2.734/0.00000

 CALML3 3.446 - 0.862 0.828 0.786 - 0.970 Mlig455_050275 {REF} {Length: 1003} {Pfam: EF hand [PF00036.34, score=85.7]; EF-hand domain pair [PF13499.8, score=77.5]; EF hand [PF13202.8, score=68.6]; EF-hand domain [PF13405.8, score=65.6]; EF-hand domain pair [PF13833.8, score=58.2]; EF-hand domain [PF14658.8, score=26.7]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=24.7]; EF hand [PF14788.8, score=20.6]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=19.9]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=79.3, Expect=3e-19]; ENSG00000198668, CALM1, calmodulin 1, [Score=78.2, Expect=9e-19]; ENSG00000143933, CALM2, calmodulin 2, [Score=77.8, Expect=1e-18]; ENSG00000160014, CALM3, calmodulin 3, [Score=77.8, Expect=1e-18]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=84.7, Expect=1e-21]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=78.6, Expect=3e-19]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=78.6, Expect=2e-19]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=78.6, Expect=2e-19]} {RNA1509_1556, RNA1509_2182, RNA1509_2532, RNA1509_4529, RNA1509_47061, RNA1509_48923, RNA1509_50214, RNA1509_6205} {RNA1310_46623, RNA1509_1556, RNA1509_2182, RNA1509_2532, RNA1509_4529, RNA1509_47061, RNA1509_48923, RNA1509_50214, RNA1509_6205} {RNA1509_1556, RNA1509_2182, RNA1509_2532, RNA1509_4529, RNA1509_47061, RNA1509_48923, RNA1509_50214, RNA1509_6205, RNA815_19933.1}
4. MligTC455_15485 26675 555.72 Mlig455_016162

Neo: -

Age: logFC(26M/2M)=0.326

Region-enriched R3: 3.027/0.00000

 2.681 - - - 0.967 0.937 0.777 Mlig455_016162 {REF} {Length: 742} {TRANSSPLICED} {RNA1509_11676, RNA1509_2084, RNA1509_22479, RNA1509_30098, RNA1509_3483, RNA1509_46712, RNA1509_47336, RNA1509_86} {RNA1310_84068.1, RNA1509_11676, RNA1509_2084, RNA1509_22479, RNA1509_30098, RNA1509_3483, RNA1509_46712, RNA1509_47336, RNA1509_86} {RNA1509_11676, RNA1509_2084, RNA1509_22479, RNA1509_30098, RNA1509_3483, RNA1509_46712, RNA1509_47336, RNA1509_86, RNA815_2945.2}
5. MligTC455_33964 17054 355.3 Mlig455_057690

Neo: -

Age: -

Region-enriched R3: 3.681/0.00000
Region-enriched R4: 2.185/0.00615

 2.591 - - - 0.875 0.752 0.964 Mlig455_057690 {REF} {Length: 582} {Pfam: Destabilase [PF05497.14, score=88.9]} {Dmel: FBgn0025827, CG6421, [Score=46.2, Expect=1e-06]} {Celegans: WBGene00016670, ilys-3, Invertebrate-type lysozyme 3, [Score=80.5, Expect=7e-20]} {RNA1509_25524} {RNA1310_5040} {RNA815_13101.1}
6. MligTC455_33965 17062 355.46 Mlig455_057693

Neo: -

Age: logFC(26M/2M)=-0.368

Region-enriched R3: 3.675/0.00000
Region-enriched R4: 2.192/0.00569

 2.591 - - - 0.875 0.752 0.964 Mlig455_057693 {REF} {Length: 618} {Pfam: Destabilase [PF05497.14, score=88.9]} {Dmel: FBgn0025827, CG6421, [Score=46.2, Expect=1e-06]} {Celegans: WBGene00016670, ilys-3, Invertebrate-type lysozyme 3, [Score=80.5, Expect=7e-20]} {RNA1509_25524} {RNA1310_5040} {RNA815_13101.2}
7. MligTC455_15486 2314 48.22 Mlig455_029035

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.725

Region-specific R3: 7.125

Region-enriched R3: 6.740/0.00000

 2.392 - 0.720 0.701 - 0.971 - Mlig455_029035 {REF} {Length: 445} {RNA1509_22994, RNA1509_37853} {RNA1310_81465, RNA1509_22994, RNA1509_37853} {RNA1509_22994, RNA1509_37853, RNA815_2945.5}
8. MligTC455_38482 16675 347.39 Mlig455_035458, Mlig455_070530

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.639

Region-enriched R3: 3.465/0.00000
Region-enriched R4: 2.322/0.00388

 TMPRSS15 1.779 - - - - 0.818 0.961

Mlig455_035458 {REF} {Length: 302} {Pfam: Motilin/ghrelin-associated peptide [PF04643.14, score=20.2]}

Mlig455_070530 {REF} {Length: 1350} {Pfam: Trypsin [PF00089.28, score=253.0]; Trypsin-like peptidase domain [PF13365.8, score=38.5]; Domain of unknown function (DUF1986) [PF09342.13, score=34.6]} {Human: ENSG00000154646, TMPRSS15, transmembrane serine protease 15, [RH, Score=195, Expect=3e-56]; ENSG00000087128, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=194, Expect=7e-59]; ENSG00000274058, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=194, Expect=7e-59]; ENSG00000105707, HPN, hepsin, [RH, Score=189, Expect=5e-57]} {Mouse: ENSMUSG00000001249, Hpn, hepsin, [RH, Score=197, Expect=3e-60]; ENSMUSG00000030800, Prss8, protease, serine 8 (prostasin), [RH, Score=192, Expect=2e-59]} {Dmel: FBgn0051954, CG31954, [RH, Score=160, Expect=1e-47]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=164, Expect=3e-49]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=173, Expect=5e-49]} {RNA1509_237, RNA1509_33683} {RNA1310_26444, RNA1509_33683} {RNA1509_33683, RNA815_9945}
9. MligTC455_41645 18825 392.18 Mlig455_056534

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.399

Region-enriched R3: 1.154/0.00411

 SELENBP1 1.705 - - - 0.750 - 0.955 Mlig455_056534 {REF} {Length: 2301} {Pfam: 56kDa selenium binding protein (SBP56) [PF05694.13, score=668.6]} {Human: ENSG00000143416, SELENBP1, selenium binding protein 1, [RH, Score=607, Expect=0.0]} {Mouse: ENSMUSG00000068874, Selenbp1, selenium binding protein 1, [RH, Score=598, Expect=0.0]; ENSMUSG00000068877, Selenbp2, selenium binding protein 2, [RH, Score=589, Expect=0.0]} {Dmel: FBgn0038115, CG7966, [RH, Score=490, Expect=6e-171]} {Celegans: WBGene00012538, Y37A1B.5, [RH, Score=524, Expect=0.0]} {RNA1509_122, RNA1509_1455} {RNA1310_13697, RNA1509_122, RNA1509_1455} {RNA1509_122, RNA1509_1455, RNA815_5156}

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