M. lignano Tomo-Seq
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Results for MligTC455_53042

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_53042 156 3.26 Mlig455_063414

Neo: -

Age: Down-Up-Up

 NKX2-2 Mlig455_063414 {REF} {Length: 1943} {Pfam: Homeodomain [PF00046.31, score=68.4]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [Score=128, Expect=2e-33]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [Score=127, Expect=2e-33]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [RH, Score=121, Expect=5e-29]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=100, Expect=1e-23]} {Smed: dd_Smed_v6_2716_0_3, dd_Smed_v6_2716_0_3, [RH, Score=115, Expect=1e-27]} {RNA1310_17555} {RNA815_11836.1}

Cumulative graph for MligTC455_53042

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -3.222 2.53 0.99973 1.00000
RegionR2 -1.41 2.53 0.95991 1.00000
RegionR3 2.303 2.53 0.01560 0.20266
RegionR4 2.127 2.53 0.06513 0.23044
RegionR5 1.806 2.53 0.06402 0.22335
RegionR6 1.11 2.53 0.32985 0.91809
RegionR7 1.153 2.53 0.40202 1.00000
RegionR8 -3.866 2.53 0.99958 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.108 2.53 0.99993 1.00000
RegenerationR2 2.002 2.53 0.01402 0.19368
RegenerationR3 0.04 2.53 0.97172 1.00000
RegenerationR4 0.441 2.53 0.57736 0.90450
RegenerationR5 0.07 2.53 0.92255 1.00000
RegenerationR6 1.184 2.53 0.10925 0.40875
RegenerationBL 2.493 2.53 0.05907 0.28219
RegenerationTP 1.682 2.53 0.43350 0.85562


Genes with expression patterns similar to MligTC455_53042

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_53042 156 3.26 Mlig455_063414

Neo: -

Age: Down-Up-Up

 NKX2-2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_063414 {REF} {Length: 1943} {Pfam: Homeodomain [PF00046.31, score=68.4]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [Score=128, Expect=2e-33]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [Score=127, Expect=2e-33]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [RH, Score=121, Expect=5e-29]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=100, Expect=1e-23]} {Smed: dd_Smed_v6_2716_0_3, dd_Smed_v6_2716_0_3, [RH, Score=115, Expect=1e-27]} {RNA1310_17555} {RNA815_11836.1}
2. MligTC455_46905 2015 41.97 Mlig455_053779

Neo: -

Age: logFC(26M/2M)=0.188

 PDPR 1.696 - - - 0.954 - 0.742 Mlig455_053779 {REF} {Length: 3098} {Pfam: FAD dependent oxidoreductase [PF01266.26, score=144.0]; FAD dependent oxidoreductase central domain [PF16350.7, score=29.7]; Aminomethyltransferase folate-binding domain [PF01571.23, score=23.4]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=21.8]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=21.0]; FAD binding domain [PF00890.26, score=19.6]} {Human: ENSG00000090857, PDPR, pyruvate dehydrogenase phosphatase regulatory subunit, [Score=305, Expect=9e-91]} {Mouse: ENSMUSG00000033624, Pdpr, pyruvate dehydrogenase phosphatase regulatory subunit, [Score=279, Expect=2e-81]} {Dmel: FBgn0029706, CG3626, [Score=249, Expect=3e-70]} {Celegans: WBGene00013718, pdpr-1, Pyruvate Dehydrogenase Phosphatase Regulatory subunit, [Score=162, Expect=3e-41]} {Smed: dd_Smed_v6_4280_0_1, dd_Smed_v6_4280_0_1, [Score=206, Expect=1e-55]} {RNA1509_23369, RNA1509_6365} {RNA1310_5958.2, RNA1509_23369} {RNA1509_23369, RNA815_1712}
3. MligTC455_21646 208 4.32 Mlig455_020902, Mlig455_020983

Neo: -

Age: Down-Up-Up

Region-enriched R5: 2.533/0.00016

 ATG16L1 1.695 - - - - 0.955 0.740

Mlig455_020902 {REF} {Length: 1821} {RNA1310_73839.1} {RNA815_29021}

Mlig455_020983 {REF} {Length: 2639} {Pfam: Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=32.0]; WD domain, G-beta repeat [PF00400.34, score=29.4]; Autophagy protein 16 (ATG16) [PF08614.13, score=28.4]} {Human: ENSG00000085978, ATG16L1, autophagy related 16 like 1, [Score=71.2, Expect=2e-12]; ENSG00000281089, ATG16L1, autophagy related 16 like 1, [Score=71.2, Expect=2e-12]} {Mouse: ENSMUSG00000026289, Atg16l1, autophagy related 16-like 1 (S. cerevisiae), [Score=69.3, Expect=4e-12]} {RNA1310_48049} {RNA815_29021}
4. MligTC455_47038 293 6.11 Mlig455_052760

Neo: -

Age: -

 0.978 - - - - 0.978 - Mlig455_052760 {REF} {Length: 57} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_55152} {RNA815_20113}
5. MligTC455_41428 1100 22.92 Mlig455_028046

Neo: -

Age: -

Region-enriched R5: 1.695/0.00005

 0.958 - - - 0.958 - - Mlig455_028046 {REF} {Length: 1663} {Pfam: Galactoside-binding lectin [PF00337.24, score=77.5]} {Mouse: ENSMUSG00000050335, Lgals3, lectin, galactose binding, soluble 3, [RH, Score=51.6, Expect=6e-07]; ENSMUSG00000053522, Lgals7, lectin, galactose binding, soluble 7, [RH, Score=49.3, Expect=6e-07]} {Dmel: FBgn0031214, CG11374, [RH, Score=70.1, Expect=7e-13]} {Celegans: WBGene00002265, lec-2, Galectin, [RH, Score=68.2, Expect=9e-13]} {RNA1509_56269} {RNA1310_22513} {RNA815_11359}
6. MligTC455_12077 535 11.15 Mlig455_050177

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.624

Region-enriched R5: 1.039/0.01695

 NPEPPS 0.953 - - - 0.953 - - Mlig455_050177 {REF} {Length: 2822} {TRANSSPLICED} {Pfam: Peptidase family M1 domain [PF01433.22, score=284.6]; ERAP1-like C-terminal domain [PF11838.10, score=263.4]; Peptidase M1 N-terminal domain [PF17900.3, score=161.4]} {Human: ENSG00000141279, NPEPPS, aminopeptidase puromycin sensitive, [Score=817, Expect=0.0]} {Mouse: ENSMUSG00000001441, Npepps, aminopeptidase puromycin sensitive, [Score=821, Expect=0.0]} {Dmel: FBgn0261243, Psa, Puromycin sensitive aminopeptidase, [Score=768, Expect=0.0]} {Celegans: WBGene00003914, pam-1, Aminopeptidase, [Score=565, Expect=0.0]} {Smed: dd_Smed_v6_1249_0_1, dd_Smed_v6_1249_0_1, [Score=743, Expect=0.0]} {RNA1509_18469, RNA1509_50562} {RNA1310_4424, RNA1509_50562} {RNA1509_50562, RNA815_16654}

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