Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_53113 | 1458 | 30.37 | Mlig455_002613 | Neo: - Age: - Region-enriched R4: 2.104/0.00626 |
MAP3K12 | Mlig455_002613 {REF} {Length: 3132} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=153.4]; Protein kinase domain [PF00069.27, score=129.5]} {Human: ENSG00000139625, MAP3K12, mitogen-activated protein kinase kinase kinase 12, [Score=250, Expect=2e-70]} {Mouse: ENSMUSG00000023050, Map3k12, mitogen-activated protein kinase kinase kinase 12, [Score=249, Expect=3e-70]} {Dmel: FBgn0036896, wnd, wallenda, [Score=248, Expect=2e-69]} {Celegans: WBGene00001008, dlk-1, Mitogen-activated protein kinase kinase kinase dlk-1, [Score=198, Expect=2e-54]} {Smed: dd_Smed_v6_8838_0_1, dd_Smed_v6_8838_0_1, [Score=209, Expect=4e-56]} {RNA1509_29308, RNA1509_37353, RNA1509_8431} {RNA1310_5009, RNA1509_29308, RNA1509_37353, RNA1509_8431} {RNA1509_29308, RNA1509_37353, RNA1509_8431, RNA815_13268} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -8.057 | 5.235 | 0.00321 | 0.18276 | |
RegionR2 | 0.92 | 5.235 | 0.24236 | 0.61832 | |
RegionR3 | 1.363 | 5.235 | 0.02288 | 0.25716 | |
RegionR4 | 2.104 | 5.235 | 0.00053 | 0.00626 | |
RegionR5 | 1.313 | 5.235 | 0.02854 | 0.12522 | |
RegionR6 | 1.153 | 5.235 | 0.07932 | 0.52080 | |
RegionR7 | 0.701 | 5.235 | 0.41171 | 1.00000 | |
RegionR8 | 0.503 | 5.235 | 0.59622 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 6.156 | 5.235 | 0.15056 | 0.89174 | |
RegenerationR2 | 0.321 | 5.235 | 0.37208 | 0.79734 | |
RegenerationR3 | -0.291 | 5.235 | 0.44720 | 0.83056 | |
RegenerationR4 | -0.351 | 5.235 | 0.38939 | 0.80712 | |
RegenerationR5 | 0.239 | 5.235 | 0.51962 | 0.86965 | |
RegenerationR6 | -0.141 | 5.235 | 0.71826 | 0.93454 | |
RegenerationBL | -0.772 | 5.235 | 0.09472 | 0.36156 | |
RegenerationTP | -0.129 | 5.235 | 0.79756 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_53113 | 1458 | 30.37 | Mlig455_002613 | Neo: - Age: - Region-enriched R4: 2.104/0.00626 |
MAP3K12 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_002613 {REF} {Length: 3132} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=153.4]; Protein kinase domain [PF00069.27, score=129.5]} {Human: ENSG00000139625, MAP3K12, mitogen-activated protein kinase kinase kinase 12, [Score=250, Expect=2e-70]} {Mouse: ENSMUSG00000023050, Map3k12, mitogen-activated protein kinase kinase kinase 12, [Score=249, Expect=3e-70]} {Dmel: FBgn0036896, wnd, wallenda, [Score=248, Expect=2e-69]} {Celegans: WBGene00001008, dlk-1, Mitogen-activated protein kinase kinase kinase dlk-1, [Score=198, Expect=2e-54]} {Smed: dd_Smed_v6_8838_0_1, dd_Smed_v6_8838_0_1, [Score=209, Expect=4e-56]} {RNA1509_29308, RNA1509_37353, RNA1509_8431} {RNA1310_5009, RNA1509_29308, RNA1509_37353, RNA1509_8431} {RNA1509_29308, RNA1509_37353, RNA1509_8431, RNA815_13268} |
2. | MligTC455_25018 | 1343 | 27.99 | Mlig455_008176 | Neo: - Age: Down-Up-Up |
TGM4 | 1.851 | 0.889 | - | - | 0.962 | - | - | Mlig455_008176 {REF} {Length: 2648} {Pfam: Transglutaminase family [PF00868.22, score=57.4]; Transglutaminase-like superfamily [PF01841.21, score=54.3]; Transglutaminase family, C-terminal ig like domain [PF00927.24, score=38.6]} {Human: ENSG00000281886, TGM4, transglutaminase 4, [Score=348, Expect=2e-109]; ENSG00000163810, TGM4, transglutaminase 4, [Score=348, Expect=2e-109]; ENSG00000104055, TGM5, transglutaminase 5, [Score=331, Expect=1e-102]} {Mouse: ENSMUSG00000027401, Tgm3, transglutaminase 3, E polypeptide, [Score=327, Expect=1e-101]; ENSMUSG00000027403, Tgm6, transglutaminase 6, [Score=327, Expect=2e-101]; ENSMUSG00000025787, Tgm4, transglutaminase 4 (prostate), [Score=324, Expect=1e-100]; ENSMUSG00000022218, Tgm1, transglutaminase 1, K polypeptide, [Score=319, Expect=2e-97]; ENSMUSG00000053675, Tgm5, transglutaminase 5, [Score=314, Expect=3e-96]} {Dmel: FBgn0031975, Tg, Transglutaminase, [Score=343, Expect=7e-107]} {RNA1509_47119, RNA1509_8950} {RNA1310_8015.1, RNA1509_47119, RNA1509_8950} {RNA1509_47119, RNA1509_8950, RNA815_2840} |
3. | MligTC455_42673 | 862 | 17.96 | Mlig455_017086 | Neo: - Age: Down-Down-Up |
1.693 | - | - | - | 0.736 | 0.957 | - | Mlig455_017086 {REF} {Length: 1828} {Pfam: Baculovirus polyhedron envelope protein, PEP, C terminus [PF04513.14, score=40.6]; TATA element modulatory factor 1 DNA binding [PF12329.10, score=31.9]; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 [PF10473.11, score=31.8]; Laminin Domain II [PF06009.14, score=31.1]; Crescentin protein [PF19220.2, score=30.6]; Bacterial protein of unknown function (DUF948) [PF06103.13, score=30.4]; Formin Homology 2 Domain [PF02181.25, score=30.2]; Intra-flagellar transport protein 57 [PF10498.11, score=29.8]; Protein of unknown function (DUF1664) [PF07889.14, score=28.6]; Growth-arrest specific micro-tubule binding [PF13851.8, score=28.6]; Domain of unknown function (DUF4201) [PF13870.8, score=27.2]; Autophagy protein 16 (ATG16) [PF08614.13, score=25.7]; Septation ring formation regulator, EzrA [PF06160.14, score=25.2]; Myelin regulatory factor ICA domain [PF13887.8, score=24.9]; TPR/MLP1/MLP2-like protein [PF07926.14, score=24.8]; Biogenesis of lysosome-related organelles complex-1 subunit 2 [PF10046.11, score=24.7]; BRE1 E3 ubiquitin ligase [PF08647.13, score=24.6]; Haemolysin XhlA [PF10779.11, score=24.6]; AAA domain [PF13166.8, score=24.6]; Seryl-tRNA synthetase N-terminal domain [PF02403.24, score=23.9]; Vps51/Vps67 [PF08700.13, score=23.9]; Domain of unknown function (DUF2935) [PF11155.10, score=23.9]; Vps53-like, N-terminal [PF04100.14, score=23.3]; Protein of unknown function (DUF713) [PF05218.16, score=23.3]; BAR domain of APPL family [PF16746.7, score=23.2]; Apolipoprotein A1/A4/E domain [PF01442.20, score=22.9]; Cholesterol uptake porter CUP1 of Mce4, putative [PF11887.10, score=22.7]; Exonuclease VII, large subunit [PF02601.17, score=22.3]; Uncharacterized conserved protein [PF10241.11, score=22.2]; Initiation control protein YabA [PF06156.15, score=22.1]; Protein of unknown function (DUF3829) [PF12889.9, score=21.9]; Flagellar FliJ protein [PF02050.18, score=21.7]; Apg6 coiled-coil region [PF17675.3, score=21.7]; Golgi transport complex subunit 5 [PF10392.11, score=21.4]; Inhibitor of growth proteins N-terminal histone-binding [PF12998.9, score=21.3]; COG (conserved oligomeric Golgi) complex component, COG2 [PF06148.13, score=21.2]; Autophagy protein ATG17-like domain [PF04108.14, score=21.0]; Prefoldin subunit [PF01920.22, score=20.6]; Zinc finger-containing protein [PF10146.11, score=20.6]; Hydrophobic surface binding protein A [PF12296.10, score=20.5]; Protein of unknown function (DUF3450) [PF11932.10, score=20.4]; TATA element modulatory factor 1 TATA binding [PF12325.10, score=20.1]; Fungal N-terminal domain of STAND proteins [PF17111.7, score=19.9]; Cell division protein ZapB [PF06005.14, score=19.8]; Tape measure protein [PF20155.1, score=19.8]; Spc7 kinetochore protein [PF08317.13, score=19.4]; Afadin- and alpha -actinin-Binding [PF11559.10, score=19.4]; Fez1 [PF06818.17, score=19.3]; Uncharacterized conserved protein (DUF2203) [PF09969.11, score=19.3]; Protein of unknown function (DUF745) [PF05335.15, score=19.2]; RNA polymerase II transcription mediator complex subunit 9 [PF07544.15, score=19.2]; DASH complex subunit Dam1 [PF08653.12, score=19.2]; TMPIT-like protein [PF07851.15, score=19.0]; Spindle and kinetochore-associated protein 1 [PF07160.14, score=18.8]; Calcium binding and coiled-coil domain (CALCOCO1) like [PF07888.13, score=18.2]; Prominin [PF05478.13, score=17.8]; Myosin tail [PF01576.21, score=17.4]} {Mouse: ENSMUSG00000043183, Simc1, SUMO-interacting motifs containing 1, [Score=74.7, Expect=4e-16]} {RNA1509_46691} {RNA1310_4498.2, RNA1509_46691} {RNA1509_46691, RNA815_1649} | |
4. | MligTC455_36614 | 481 | 10.01 | Mlig455_002969, Mlig455_049084 | Neo: - Age: Up-Down-Down |
RNF13 | 0.961 | - | - | - | - | - | 0.961 | Mlig455_002969 {REF} {Length: 682} {Pfam: Hydrophobic surface binding protein A [PF12296.10, score=21.2]; Flocculin repeat [PF00624.20, score=19.6]} {RNA1310_44296} {RNA815_35577} Mlig455_049084 {REF} {Length: 3354} {TRANSSPLICED} {Pfam: RING-like zinc finger [PF17123.7, score=47.7]; Ring finger domain [PF13639.8, score=46.8]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=32.1]; zinc-RING finger domain [PF14634.8, score=26.6]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=25.5]; RING-type zinc-finger [PF13445.8, score=25.2]; RING-H2 zinc finger domain [PF12678.9, score=25.1]; Prokaryotic RING finger family 4 [PF14447.8, score=24.8]; PA domain [PF02225.24, score=23.2]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=19.6]} {Human: ENSG00000082996, RNF13, ring finger protein 13, [RH, Score=192, Expect=2e-56]} {Mouse: ENSMUSG00000036503, Rnf13, ring finger protein 13, [RH, Score=195, Expect=8e-58]} {Dmel: FBgn0037442, godzilla, godzilla E3 ubiquitin protein ligase, [RH, Score=152, Expect=1e-40]} {Celegans: WBGene00007666, C18B12.4, [RH, Score=140, Expect=1e-36]} {Smed: dd_Smed_v6_10741_0_2, dd_Smed_v6_10741_0_2, [RH, Score=84.7, Expect=8e-18]} {RNA1509_13438} {RNA1310_21318.1} {RNA815_6447} |
5. | MligTC455_39546 | 1581 | 32.95 | Mlig455_044795, Mlig455_055563 | Neo: - Age: Down-Up-Up |
PDE6D | 0.958 | - | - | - | - | - | 0.958 | Mlig455_044795 {REF} {Length: 2791} {TRANSSPLICED} {Pfam: GMP-PDE, delta subunit [PF05351.13, score=60.7]; Protein of unknown function (DUF2515) [PF10720.11, score=19.5]} {Human: ENSG00000156973, PDE6D, phosphodiesterase 6D, [RH, Score=137, Expect=5e-40]} {Mouse: ENSMUSG00000026239, Pde6d, phosphodiesterase 6D, cGMP-specific, rod, delta, [Score=140, Expect=2e-40]} {Dmel: FBgn0032059, PrBP, Prenyl-binding protein, [Score=105, Expect=4e-27]} {Celegans: WBGene00003966, pdl-1, Phosphodiesterase delta-like protein, [Score=119, Expect=2e-32]} {Smed: dd_Smed_v6_9168_0_9, dd_Smed_v6_9168_0_9, [Score=134, Expect=2e-38]} {RNA1509_4210, RNA1509_8099} {RNA1310_21694, RNA1509_8099} {RNA1509_8099, RNA815_8937} Mlig455_055563 {REF} {Length: 1915} {TRANSSPLICED} {Pfam: GMP-PDE, delta subunit [PF05351.13, score=151.3]} {Human: ENSG00000156973, PDE6D, phosphodiesterase 6D, [RH, Score=244, Expect=5e-84]} {Mouse: ENSMUSG00000026239, Pde6d, phosphodiesterase 6D, cGMP-specific, rod, delta, [RH, Score=244, Expect=2e-84]} {Dmel: FBgn0032059, PrBP, Prenyl-binding protein, [RH, Score=191, Expect=3e-63]} {Celegans: WBGene00003966, pdl-1, Phosphodiesterase delta-like protein, [RH, Score=220, Expect=9e-75]} {Smed: dd_Smed_v6_9168_0_4, dd_Smed_v6_9168_0_4, [RH, Score=232, Expect=5e-80]} {RNA1509_4210} {RNA1310_21694} {RNA815_8937} |
6. | MligTC455_23147 | 1901 | 39.61 | Mlig455_047162, Mlig455_048520 | Neo: - Age: - |
ATP9B | 0.952 | - | - | 0.952 | - | - | - | Mlig455_047162 {REF} {Length: 4662} {Pfam: Phospholipid-translocating P-type ATPase C-terminal [PF16212.7, score=149.4]; haloacid dehalogenase-like hydrolase [PF00702.28, score=52.5]; E1-E2 ATPase [PF00122.22, score=41.5]; Phospholipid-translocating ATPase N-terminal [PF16209.7, score=41.0]; Cation transport ATPase (P-type) [PF13246.8, score=35.7]} {Human: ENSG00000166377, ATP9B, ATPase phospholipid transporting 9B (putative), [Score=1040, Expect=0.0]; ENSG00000054793, ATP9A, ATPase phospholipid transporting 9A (putative), [Score=1014, Expect=0.0]} {Mouse: ENSMUSG00000024566, Atp9b, ATPase, class II, type 9B, [Score=1026, Expect=0.0]; ENSMUSG00000027546, Atp9a, ATPase, class II, type 9A, [Score=1016, Expect=0.0]} {Dmel: FBgn0051729, CG31729, [Score=1011, Expect=0.0]} {Celegans: WBGene00009498, tat-5, Phospholipid-transporting ATPase, [Score=936, Expect=0.0]} {Smed: dd_Smed_v6_2913_0_2, dd_Smed_v6_2913_0_2, [Score=1076, Expect=0.0]} {RNA1509_16271, RNA1509_7231} {RNA1310_1570.2, RNA1509_16271, RNA1509_7231} {RNA1509_16271, RNA1509_7231, RNA815_134.1} Mlig455_048520 {REF} {Length: 3804} {TRANSSPLICED} {Pfam: Phospholipid-translocating P-type ATPase C-terminal [PF16212.7, score=114.8]; haloacid dehalogenase-like hydrolase [PF00702.28, score=51.5]; E1-E2 ATPase [PF00122.22, score=39.2]; Cation transport ATPase (P-type) [PF13246.8, score=36.7]} {Human: ENSG00000166377, ATP9B, ATPase phospholipid transporting 9B (putative), [Score=946, Expect=0.0]; ENSG00000054793, ATP9A, ATPase phospholipid transporting 9A (putative), [Score=932, Expect=0.0]} {Mouse: ENSMUSG00000024566, Atp9b, ATPase, class II, type 9B, [Score=932, Expect=0.0]; ENSMUSG00000027546, Atp9a, ATPase, class II, type 9A, [Score=932, Expect=0.0]} {Dmel: FBgn0051729, CG31729, [Score=914, Expect=0.0]} {Celegans: WBGene00009498, tat-5, Phospholipid-transporting ATPase, [Score=843, Expect=0.0]} {Smed: dd_Smed_v6_2913_0_1, dd_Smed_v6_2913_0_1, [Score=983, Expect=0.0]} {RNA1509_16271} {RNA1310_1570.1} {RNA815_134.1} |
7. | MligTC455_32938 | 319 | 6.64 | Mlig455_039489 | Neo: - Age: logFC(26M/2M)=-0.529 |
0.95 | - | - | - | - | 0.950 | - | Mlig455_039489 {REF} {Length: 1665} {RNA1509_14386} {RNA1310_21532} {RNA815_8850} |