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Results for MligTC455_53290

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_53290 1103 22.98 Mlig455_028042

Neo: Germline

Age: -

Region-enriched R4: 1.812/0.00135
Region-enriched R5: 1.083/0.02034

RHBDD1 Mlig455_028042 {REF} {Length: 1200} {Pfam: Rhomboid family [PF01694.24, score=80.0]} {Human: ENSG00000144468, RHBDD1, rhomboid domain containing 1, [RH, Score=179, Expect=6e-54]} {Mouse: ENSMUSG00000026142, Rhbdd1, rhomboid domain containing 1, [RH, Score=180, Expect=2e-54]} {Smed: dd_Smed_v6_8991_0_1, dd_Smed_v6_8991_0_1, [RH, Score=144, Expect=4e-41]} {RNA1509_23700, RNA1509_31667} {RNA1310_30472, RNA1509_23700} {RNA1509_23700, RNA815_4865}

Cumulative graph for MligTC455_53290

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.851 4.793 0.30214 0.95197
RegionR2 -1.241 4.793 0.01606 0.13439
RegionR3 -0.752 4.793 0.07621 0.48891
RegionR4 1.812 4.793 0.00008 0.00135
RegionR5 1.083 4.793 0.00245 0.02034
RegionR6 -0.156 4.793 0.70608 1.00000
RegionR7 -0.592 4.793 0.24529 0.87195
RegionR8 -1.005 4.793 0.13160 0.66452

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.288 4.793 0.25953 0.96822
RegenerationR2 0.284 4.793 0.54789 0.89194
RegenerationR3 0.226 4.793 0.65915 0.93291
RegenerationR4 -1.388 4.793 0.00630 0.11420
RegenerationR5 -0.438 4.793 0.33211 0.75295
RegenerationR6 -0.159 4.793 0.75016 0.95230
RegenerationBL 0.212 4.793 0.69213 1.00000
RegenerationTP 0.347 4.793 0.56190 0.93966


Genes with expression patterns similar to MligTC455_53290

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_53290 1103 22.98 Mlig455_028042

Neo: Germline

Age: -

Region-enriched R4: 1.812/0.00135
Region-enriched R5: 1.083/0.02034

RHBDD1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_028042 {REF} {Length: 1200} {Pfam: Rhomboid family [PF01694.24, score=80.0]} {Human: ENSG00000144468, RHBDD1, rhomboid domain containing 1, [RH, Score=179, Expect=6e-54]} {Mouse: ENSMUSG00000026142, Rhbdd1, rhomboid domain containing 1, [RH, Score=180, Expect=2e-54]} {Smed: dd_Smed_v6_8991_0_1, dd_Smed_v6_8991_0_1, [RH, Score=144, Expect=4e-41]} {RNA1509_23700, RNA1509_31667} {RNA1310_30472, RNA1509_23700} {RNA1509_23700, RNA815_4865}
2. MligTC455_20987 1769 36.85 Mlig455_028383, Mlig455_035961

Neo: Irradiation

Age: -

Region-specific R5: 2.292

Region-enriched R5: 2.053/0.00000

2.61 0.717 - - - 0.953 0.940

Mlig455_028383 {REF} {Length: 1097} {TRANSSPLICED} {Pfam: Geminin [PF07412.14, score=23.4]} {RNA1509_12313} {RNA1310_31319} {RNA815_14142}

Mlig455_035961 {REF} {Length: 1098} {TRANSSPLICED} {Pfam: Geminin [PF07412.14, score=23.1]} {RNA1509_12313} {RNA1310_31319} {RNA815_14142}
3. MligTC455_41228 892 18.59 Mlig455_029646

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.317

Region-enriched R5: 1.550/0.00080

SAFB 2.576 - - - 0.776 0.983 0.817 Mlig455_029646 {REF} {Length: 2473} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=35.8]} {Human: ENSG00000160633, SAFB, scaffold attachment factor B, [Score=65.9, Expect=2e-10]} {Mouse: ENSMUSG00000071054, Safb, scaffold attachment factor B, [Score=61.6, Expect=2e-09]} {RNA1509_11846, RNA1509_41823} {RNA1310_8499, RNA1509_11846, RNA1509_41823} {RNA1509_11846, RNA1509_41823, RNA815_6853}
4. MligTC455_44108 2515 52.4 Mlig455_014945, Mlig455_045147, Mlig455_045181

Neo: Neoblast, stringent

Age: Down-Up-Up, logFC(26M/2M)=0.297

Region-specific R5: 2.328

Region-enriched R5: 2.074/0.00000

TDP2 2.531 0.734 - - - 0.842 0.955

Mlig455_014945 {REF} {Length: 1215} {Pfam: UBA-like domain [PF14555.8, score=27.9]; Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=25.5]} {Human: ENSG00000111802, TDP2, tyrosyl-DNA phosphodiesterase 2, [RH, Score=169, Expect=4e-49]} {Mouse: ENSMUSG00000035958, Tdp2, tyrosyl-DNA phosphodiesterase 2, [RH, Score=163, Expect=4e-47]} {Celegans: WBGene00013405, tdpt-1, 5'-tyrosyl-DNA phosphodiesterase, [RH, Score=149, Expect=6e-42]} {Smed: dd_Smed_v6_12962_0_2, dd_Smed_v6_12962_0_2, [RH, Score=177, Expect=5e-53]} {RNA1509_7675} {RNA1310_28437, RNA1509_7675} {RNA1509_7675, RNA815_27699}

Mlig455_045147 {REF} {Length: 1223} {TRANSSPLICED} {Pfam: UBA-like domain [PF14555.8, score=28.7]; Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=25.5]} {Human: ENSG00000111802, TDP2, tyrosyl-DNA phosphodiesterase 2, [RH, Score=171, Expect=7e-50]} {Mouse: ENSMUSG00000035958, Tdp2, tyrosyl-DNA phosphodiesterase 2, [RH, Score=166, Expect=6e-48]} {Celegans: WBGene00013405, tdpt-1, 5'-tyrosyl-DNA phosphodiesterase, [RH, Score=148, Expect=1e-41]} {Smed: dd_Smed_v6_12962_0_2, dd_Smed_v6_12962_0_2, [RH, Score=178, Expect=1e-53]} {RNA1509_7675} {RNA1310_28437} {RNA815_27699}

Mlig455_045181 {REF} {Length: 1222} {Pfam: UBA-like domain [PF14555.8, score=28.7]; Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=25.5]} {Human: ENSG00000111802, TDP2, tyrosyl-DNA phosphodiesterase 2, [RH, Score=171, Expect=7e-50]} {Mouse: ENSMUSG00000035958, Tdp2, tyrosyl-DNA phosphodiesterase 2, [RH, Score=166, Expect=6e-48]} {Celegans: WBGene00013405, tdpt-1, 5'-tyrosyl-DNA phosphodiesterase, [RH, Score=148, Expect=1e-41]} {Smed: dd_Smed_v6_12962_0_2, dd_Smed_v6_12962_0_2, [RH, Score=178, Expect=1e-53]} {RNA1509_7675} {RNA1310_28437} {RNA815_27699}
5. MligTC455_40013 1551 32.32 Mlig455_045254, Mlig455_069174

Neo: Neoblast, stringent

Age: -

Region-enriched R5: 1.916/0.00000

Regeneration-upregulated BL: 1.957

Regeneration-enriched BL: 1.957

MCM5 2.422 0.742 - - - 0.956 0.724

Mlig455_045254 {REF} {Length: 2658} {Pfam: MCM P-loop domain [PF00493.25, score=329.8]; MCM OB domain [PF17207.5, score=115.3]; MCM AAA-lid domain [PF17855.3, score=92.5]; MCM N-terminal domain [PF14551.8, score=58.6]; Magnesium chelatase, subunit ChlI [PF01078.23, score=25.3]; AAA domain (dynein-related subfamily) [PF07728.16, score=20.5]} {Human: ENSG00000100297, MCM5, minichromosome maintenance complex component 5, [RH, Score=937, Expect=0.0]} {Mouse: ENSMUSG00000005410, Mcm5, minichromosome maintenance complex component 5, [RH, Score=937, Expect=0.0]} {Dmel: FBgn0017577, Mcm5, Minichromosome maintenance 5, [RH, Score=892, Expect=0.0]} {Celegans: WBGene00003157, mcm-5, DNA replication licensing factor mcm-5, [RH, Score=800, Expect=0.0]} {Smed: dd_Smed_v6_5764_0_1, dd_Smed_v6_5764_0_1, [RH, Score=834, Expect=0.0]} {RNA1509_4580} {RNA1310_6377} {RNA815_5726}

Mlig455_069174 {REF} {Length: 3194} {Pfam: MCM P-loop domain [PF00493.25, score=329.3]; MCM OB domain [PF17207.5, score=114.9]; MCM AAA-lid domain [PF17855.3, score=92.4]; MCM N-terminal domain [PF14551.8, score=57.1]; Magnesium chelatase, subunit ChlI [PF01078.23, score=24.9]; Endonuclease-reverse transcriptase [PF14529.8, score=21.0]; AAA domain (dynein-related subfamily) [PF07728.16, score=20.1]} {Human: ENSG00000100297, MCM5, minichromosome maintenance complex component 5, [RH, Score=932, Expect=0.0]} {Mouse: ENSMUSG00000005410, Mcm5, minichromosome maintenance complex component 5, [RH, Score=929, Expect=0.0]} {Dmel: FBgn0017577, Mcm5, Minichromosome maintenance 5, [RH, Score=890, Expect=0.0]} {Celegans: WBGene00003157, mcm-5, DNA replication licensing factor mcm-5, [RH, Score=803, Expect=0.0]} {Smed: dd_Smed_v6_5764_0_1, dd_Smed_v6_5764_0_1, [RH, Score=833, Expect=0.0]} {RNA1509_4580} {RNA1310_6377} {RNA815_5726}
6. MligTC455_25250 21119 439.97 Mlig455_009753, Mlig455_070108

Neo: Germline

Age: -

Region-specific R5: 2.094
Region-specific R4: 1.762

Region-enriched R5: 1.516/0.00000

DDX6 2.406 0.751 0.704 - - - 0.951

Mlig455_009753 {REF} {Length: 3240} {TRANSSPLICED} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=147.1]; Helicase conserved C-terminal domain [PF00271.33, score=98.3]} {Human: ENSG00000110367, DDX6, DEAD-box helicase 6, [RH, Score=659, Expect=0.0]} {Mouse: ENSMUSG00000032097, Ddx6, DEAD (Asp-Glu-Ala-Asp) box polypeptide 6, [RH, Score=659, Expect=0.0]} {Dmel: FBgn0004419, me31B, maternal expression at 31B, [RH, Score=651, Expect=0.0]} {Celegans: WBGene00000479, cgh-1, ATP-dependent RNA helicase cgh-1, [RH, Score=641, Expect=0.0]} {Smed: dd_Smed_v6_1034_0_1, dd_Smed_v6_1034_0_1, [RH, Score=701, Expect=0.0]} {RNA1509_16545, RNA1509_2093} {RNA1310_2612, RNA1509_16545} {RNA1509_16545, RNA815_1155.1}

Mlig455_070108 {REF} {Length: 3239} {TRANSSPLICED} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=147.1]; Helicase conserved C-terminal domain [PF00271.33, score=98.3]} {Human: ENSG00000110367, DDX6, DEAD-box helicase 6, [RH, Score=659, Expect=0.0]} {Mouse: ENSMUSG00000032097, Ddx6, DEAD (Asp-Glu-Ala-Asp) box polypeptide 6, [RH, Score=659, Expect=0.0]} {Dmel: FBgn0004419, me31B, maternal expression at 31B, [RH, Score=651, Expect=0.0]} {Celegans: WBGene00000479, cgh-1, ATP-dependent RNA helicase cgh-1, [RH, Score=641, Expect=0.0]} {Smed: dd_Smed_v6_1034_0_1, dd_Smed_v6_1034_0_1, [RH, Score=701, Expect=0.0]} {RNA1509_2093, RNA1509_85} {RNA1310_2612, RNA1509_2093, RNA1509_85} {RNA1509_2093, RNA1509_85, RNA815_1155.1}
7. MligTC455_25981 970 20.21 Mlig455_020309

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.666

Region-enriched R5: 2.043/0.00000

FIGNL1 1.859 - - - - 0.956 0.903 Mlig455_020309 {REF} {Length: 2500} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=125.9]; AAA+ lid domain [PF17862.3, score=34.7]; AAA domain (dynein-related subfamily) [PF07728.16, score=24.7]; Vps4 C terminal oligomerisation domain [PF09336.12, score=21.0]} {Human: ENSG00000132436, FIGNL1, fidgetin like 1, [RH, Score=439, Expect=3e-146]} {Mouse: ENSMUSG00000035455, Fignl1, fidgetin-like 1, [RH, Score=436, Expect=4e-145]} {Dmel: FBgn0031519, Fign, Fidgetin, [RH, Score=320, Expect=4e-102]} {Celegans: WBGene00017981, figl-1, Fidgetin-like protein 1, [RH, Score=338, Expect=2e-108]} {Smed: dd_Smed_v6_14599_0_2, dd_Smed_v6_14599_0_2, [RH, Score=394, Expect=2e-130]} {RNA1509_15082, RNA1509_24009} {RNA1310_15510, RNA1509_15082, RNA1509_24009} {RNA1509_15082, RNA1509_24009, RNA815_18261}
8. MligTC455_19318 990 20.62 Mlig455_010814, Mlig455_033227

Neo: Int S/G2/M

Age: Down-Up-Up

Region-enriched R5: 2.132/0.00000

1.7 - - - - 0.736 0.964

Mlig455_010814 {REF} {Length: 1904} {TRANSSPLICED} {Pfam: piRNA pathway germ-plasm component [PF13017.8, score=55.0]} {RNA1509_35796} {RNA1310_15021} {RNA815_14322}

Mlig455_033227 {REF} {Length: 1899} {TRANSSPLICED} {Pfam: piRNA pathway germ-plasm component [PF13017.8, score=54.2]} {RNA1509_17101, RNA1509_35796, RNA1509_45978} {RNA1310_15021, RNA1509_17101, RNA1509_35796, RNA1509_45978} {RNA1509_17101, RNA1509_35796, RNA1509_45978, RNA815_14322}
9. MligTC455_22170 321 6.68 Mlig455_029360

Neo: Irradiation

Age: Down-Up-Up, logFC(26M/2M)=0.300

CPSF2 0.958 - - - - - 0.958 Mlig455_029360 {REF} {Length: 2588} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily domain [PF16661.7, score=195.4]; Cleavage and polyadenylation factor 2 C-terminal [PF13299.8, score=92.1]; Beta-Casp domain [PF10996.10, score=67.8]; Zn-dependent metallo-hydrolase RNA specificity domain [PF07521.14, score=37.9]; Beta-lactamase superfamily domain [PF12706.9, score=22.2]; Metallo-beta-lactamase superfamily [PF00753.29, score=19.6]} {Human: ENSG00000165934, CPSF2, cleavage and polyadenylation specific factor 2, [RH, Score=660, Expect=0.0]} {Mouse: ENSMUSG00000041781, Cpsf2, cleavage and polyadenylation specific factor 2, [RH, Score=662, Expect=0.0]} {Dmel: FBgn0027873, Cpsf100, Cleavage and polyadenylation specificity factor 100, [RH, Score=651, Expect=0.0]} {Celegans: WBGene00017313, cpsf-2, Probable cleavage and polyadenylation specificity factor subunit 2, [RH, Score=410, Expect=4e-131]} {Smed: dd_Smed_v6_5812_0_1, dd_Smed_v6_5812_0_1, [RH, Score=624, Expect=0.0]} {RNA1509_30533, RNA1509_6127} {RNA1310_6453, RNA1509_30533, RNA1509_6127} {RNA1509_30533, RNA1509_6127, RNA815_10477}
10. MligTC455_20022 767 15.97 Mlig455_022377, Mlig455_022465

Neo: Int S/G2/M

Age: Down-Up-Up, logFC(26M/2M)=0.385

Region-enriched R5: 1.142/0.02757

NSD2 0.954 - - - - - 0.954

Mlig455_022377 {REF} {Length: 3316} {TRANSSPLICED} {Pfam: PWWP domain [PF00855.19, score=107.7]; PHD-finger [PF00628.31, score=33.9]; AWS domain [PF17907.3, score=22.3]} {Human: ENSG00000109685, NSD2, nuclear receptor binding SET domain protein 2, [Score=208, Expect=2e-54]; ENSG00000165671, NSD1, nuclear receptor binding SET domain protein 1, [Score=198, Expect=4e-51]} {Mouse: ENSMUSG00000057406, Nsd2, nuclear receptor binding SET domain protein 2, [Score=209, Expect=5e-55]; ENSMUSG00000021488, Nsd1, nuclear receptor-binding SET-domain protein 1, [Score=200, Expect=8e-52]} {Dmel: FBgn0039559, NSD, Nuclear receptor binding SET domain protein, [Score=168, Expect=4e-42]} {Smed: dd_Smed_v6_10189_0_1, dd_Smed_v6_10189_0_1, [Score=187, Expect=8e-49]} {RNA1509_22588} {RNA1310_10794.1} {RNA815_16118}

Mlig455_022465 {REF} {Length: 3496} {Pfam: PWWP domain [PF00855.19, score=107.2]; PHD-finger [PF00628.31, score=33.7]; AWS domain [PF17907.3, score=21.0]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=18.7]} {Human: ENSG00000109685, NSD2, nuclear receptor binding SET domain protein 2, [Score=206, Expect=9e-54]} {Mouse: ENSMUSG00000057406, Nsd2, nuclear receptor binding SET domain protein 2, [Score=207, Expect=3e-54]; ENSMUSG00000021488, Nsd1, nuclear receptor-binding SET-domain protein 1, [Score=197, Expect=8e-51]} {Dmel: FBgn0039559, NSD, Nuclear receptor binding SET domain protein, [Score=170, Expect=1e-42]} {Smed: dd_Smed_v6_4755_0_1, dd_Smed_v6_4755_0_1, [Score=184, Expect=3e-48]} {RNA1509_22588} {RNA1310_10794.1} {RNA815_16118}
11. MligTC455_48288 459 9.55 Mlig455_025872, Mlig455_025962

Neo: Int S/G2/M

Age: Up-Down-Up, logFC(26M/2M)=1.174

Region-enriched R5: 2.252/0.00477

0.951 - - - - - 0.951

Mlig455_025872 {REF} {Length: 1078} {TRANSSPLICED} {RNA1509_54367} {RNA1310_36589.1, RNA1509_54367} {RNA1509_54367, RNA815_54285}

Mlig455_025962 {REF} {Length: 989} {TRANSSPLICED} {RNA1509_54367} {RNA1310_36589.1} {RNA815_54285}

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