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Results for MligTC455_53403

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_53403 375 7.81 Mlig455_011874, Mlig455_011900

Neo: -

Age: -

Mlig455_011874 {REF} {Length: 4793} {RNA1509_42557} {RNA1310_8919.1} {RNA815_1755}

Mlig455_011900 {REF} {Length: 672} {Pfam: Protein of unknown function (DUF725) [PF05267.14, score=19.2]} {RNA1509_42557} {RNA1310_3763} {RNA815_8008.1}

Cumulative graph for MligTC455_53403

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.42 3.117 0.72700 1.00000
RegionR2 0.652 3.117 0.25576 0.63634
RegionR3 -0.279 3.117 0.60512 1.00000
RegionR4 -0.871 3.117 0.13085 0.36644
RegionR5 -2.126 3.117 0.00024 0.00327
RegionR6 -0.127 3.117 0.82092 1.00000
RegionR7 1.226 3.117 0.04061 0.38537
RegionR8 1.105 3.117 0.16417 0.73298

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.268 3.117 0.47687 1.00000
RegenerationR2 -0.203 3.117 0.67687 0.94783
RegenerationR3 0.287 3.117 0.63312 0.92177
RegenerationR4 0.121 3.117 0.83578 0.99916
RegenerationR5 1.178 3.117 0.07190 0.42090
RegenerationR6 0.557 3.117 0.33738 0.68368
RegenerationBL -0.001 3.117 0.99400 1.00000
RegenerationTP -0.298 3.117 0.63754 0.98205


Genes with expression patterns similar to MligTC455_53403

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_53403 375 7.81 Mlig455_011874, Mlig455_011900

Neo: -

Age: -

6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_011874 {REF} {Length: 4793} {RNA1509_42557} {RNA1310_8919.1} {RNA815_1755}

Mlig455_011900 {REF} {Length: 672} {Pfam: Protein of unknown function (DUF725) [PF05267.14, score=19.2]} {RNA1509_42557} {RNA1310_3763} {RNA815_8008.1}
2. MligTC455_53400 345 7.18 Mlig455_011902

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.726

5.881 0.989 0.999 0.992 0.988 0.921 0.992 Mlig455_011902 {REF} {Length: 1541} {RNA1509_4217} {RNA1310_16120} {RNA815_27428}
3. MligTC455_07182 156 3.26 Mlig455_060033

Neo: -

Age: Down-Up-Up

OXTR 1.876 0.917 0.959 - - - - Mlig455_060033 {REF} {Length: 1704} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=44.6]} {Human: ENSG00000180914, OXTR, oxytocin receptor, [Score=48.9, Expect=1e-05]} {Mouse: ENSMUSG00000049112, Oxtr, oxytocin receptor, [Score=50.1, Expect=3e-06]} {Smed: dd_Smed_v6_27989_0_1, dd_Smed_v6_27989_0_1, [RH, Score=164, Expect=8e-47]} {RNA1310_22580} {RNA815_25223}
4. MligTC455_32077 240 4.99 Mlig455_032957

Neo: -

Age: -

1.836 - 0.966 0.870 - - - Mlig455_032957 {REF} {Length: 4172} {TRANSSPLICED} {RNA1509_19305, RNA1509_34564} {RNA1310_20429.1, RNA1509_19305, RNA1509_34564} {RNA1509_19305, RNA1509_34564, RNA815_7869}
5. MligTC455_09236 361 7.53 Mlig455_069872

Neo: -

Age: -

1.733 - 0.965 0.768 - - - Mlig455_069872 {REF} {Length: 971} {NoTransDecoderORF} {RNA1509_56890} {RNA1310_8409.1} {RNA815_29944}
6. MligTC455_17119 145 3.03 Mlig455_027733, Mlig455_027947

Neo: -

Age: -

PCMT1 1.688 - - 0.957 0.731 - -

Mlig455_027733 {REF} {Length: 807} {TRANSSPLICED} {Pfam: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=214.3]; Methyltransferase domain [PF13847.8, score=31.2]; Methyltransferase domain [PF13649.8, score=26.1]; tRNA methyltransferase complex GCD14 subunit [PF08704.12, score=22.7]; Methyltransferase domain [PF08241.14, score=21.0]; Methyltransferase domain [PF13679.8, score=19.7]} {Human: ENSG00000120265, PCMT1, protein-L-isoaspartate (D-aspartate) O-methyltransferase, [Score=204, Expect=6e-66]} {Mouse: ENSMUSG00000116405, Pcmt1, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, [Score=201, Expect=2e-64]; ENSMUSG00000019795, Pcmt1, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, [Score=201, Expect=2e-64]} {Dmel: FBgn0086768, Pcmt, Protein-L-isoaspartate (D-aspartate) O-methyltransferase, [Score=182, Expect=1e-57]} {Celegans: WBGene00003954, pcm-1, Protein-L-isoaspartate O-methyltransferase, [Score=187, Expect=1e-59]} {Smed: dd_Smed_v6_6199_0_1, dd_Smed_v6_6199_0_1, [Score=185, Expect=1e-58]} {RNA1310_30151} {RNA815_54398}

Mlig455_027947 {REF} {Length: 807} {TRANSSPLICED} {Pfam: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=214.3]; Methyltransferase domain [PF13847.8, score=31.2]; Methyltransferase domain [PF13649.8, score=26.1]; tRNA methyltransferase complex GCD14 subunit [PF08704.12, score=22.7]; Methyltransferase domain [PF08241.14, score=21.0]; Methyltransferase domain [PF13679.8, score=19.7]} {Human: ENSG00000120265, PCMT1, protein-L-isoaspartate (D-aspartate) O-methyltransferase, [Score=204, Expect=6e-66]} {Mouse: ENSMUSG00000116405, Pcmt1, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, [Score=201, Expect=2e-64]; ENSMUSG00000019795, Pcmt1, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, [Score=201, Expect=2e-64]} {Dmel: FBgn0086768, Pcmt, Protein-L-isoaspartate (D-aspartate) O-methyltransferase, [Score=182, Expect=1e-57]} {Celegans: WBGene00003954, pcm-1, Protein-L-isoaspartate O-methyltransferase, [Score=187, Expect=1e-59]} {Smed: dd_Smed_v6_6199_0_1, dd_Smed_v6_6199_0_1, [Score=185, Expect=1e-58]} {RNA1310_30151} {RNA815_54398}
7. MligTC455_40018 295 6.15 Mlig455_037646, Mlig455_069914

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.048

Region-enriched R8: 4.445/0.00001
Region-enriched R7: 3.788/0.00007

AC243734.1, CHRNA2 1.684 0.950 - - - - 0.734

Mlig455_037646 {REF} {Length: 2101} {TRANSSPLICED} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=46.2]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=27.0]} {Human: ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=68.9, Expect=6e-12]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=65.5, Expect=8e-11]} {Mouse: ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=75.5, Expect=3e-14]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=73.2, Expect=2e-13]} {Dmel: FBgn0032151, nAChRalpha6, nicotinic Acetylcholine Receptor alpha6, [Score=82.8, Expect=9e-17]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=71.2, Expect=4e-13]} {Smed: dd_Smed_v6_8486_0_1, dd_Smed_v6_8486_0_1, [Score=78.2, Expect=2e-15]} {RNA1509_50033} {RNA1310_22440} {RNA815_15508}

Mlig455_069914 {REF} {Length: 3748} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=68.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=60.3]} {Human: ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=108, Expect=5e-25]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=108, Expect=9e-25]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=108, Expect=5e-25]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=107, Expect=1e-24]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=99.4, Expect=5e-22]} {Celegans: WBGene00000951, deg-3, Acetylcholine receptor subunit alpha-type deg-3, [Score=94.0, Expect=3e-20]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=113, Expect=7e-27]} {RNA1509_50033} {RNA1310_16096, RNA1509_50033} {RNA1509_50033, RNA815_15508}
8. MligTC455_30750 2067 43.07 Mlig455_051133, Mlig455_063036

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.340

1.675 0.962 - - - 0.713 -

Mlig455_051133 {REF} {Length: 1343} {Pfam: Methyltransferase FkbM domain [PF05050.14, score=18.9]} {RNA1509_7841} {RNA1310_50281} {RNA815_3607}

Mlig455_063036 {REF} {Length: 2534} {Smed: dd_Smed_v6_25359_0_1, dd_Smed_v6_25359_0_1, [Score=73.9, Expect=1e-14]} {RNA1509_31595, RNA1509_31688, RNA1509_7841} {RNA1310_29896, RNA1509_31595, RNA1509_31688, RNA1509_7841} {RNA1509_31595, RNA1509_31688, RNA1509_7841, RNA815_3607}
9. MligTC455_53107 399 8.31 Mlig455_064007, Mlig455_064048

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.483

CALM1 1.673 0.956 - - - 0.717 -

Mlig455_064007 {REF} {Length: 822} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=120.8]; EF-hand domain pair [PF13499.8, score=117.4]; EF-hand domain pair [PF13833.8, score=95.4]; EF-hand domain [PF13405.8, score=90.8]; EF hand [PF13202.8, score=88.8]; EF-hand domain [PF14658.8, score=61.4]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=44.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=29.6]; Caleosin related protein [PF05042.15, score=20.6]; Dockerin type I domain [PF00404.20, score=20.0]; Family of unknown function (DUF5580) [PF17743.3, score=17.5]} {Human: ENSG00000198668, CALM1, calmodulin 1, [Score=211, Expect=1e-70]; ENSG00000160014, CALM3, calmodulin 3, [Score=211, Expect=1e-70]; ENSG00000143933, CALM2, calmodulin 2, [Score=211, Expect=1e-70]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=211, Expect=8e-71]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=211, Expect=8e-71]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=211, Expect=8e-71]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=202, Expect=2e-67]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=212, Expect=2e-71]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=212, Expect=2e-71]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=212, Expect=2e-71]} {RNA1509_31589} {RNA1310_15824} {RNA815_18405}

Mlig455_064048 {REF} {Length: 818} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=120.8]; EF-hand domain pair [PF13499.8, score=117.4]; EF-hand domain pair [PF13833.8, score=95.4]; EF-hand domain [PF13405.8, score=90.8]; EF hand [PF13202.8, score=88.8]; EF-hand domain [PF14658.8, score=61.4]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=44.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=29.6]; Caleosin related protein [PF05042.15, score=20.6]; Dockerin type I domain [PF00404.20, score=20.0]; Family of unknown function (DUF5580) [PF17743.3, score=17.5]} {Human: ENSG00000198668, CALM1, calmodulin 1, [Score=211, Expect=1e-70]; ENSG00000160014, CALM3, calmodulin 3, [Score=211, Expect=1e-70]; ENSG00000143933, CALM2, calmodulin 2, [Score=211, Expect=1e-70]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=211, Expect=8e-71]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=211, Expect=8e-71]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=211, Expect=8e-71]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=202, Expect=2e-67]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=212, Expect=2e-71]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=212, Expect=2e-71]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=212, Expect=2e-71]} {RNA1509_31589} {RNA1310_15824, RNA1509_31589} {RNA1509_31589, RNA815_18405}
10. MligTC455_20141 2842 59.2 Mlig455_007030, Mlig455_069136

Neo: -

Age: Down-Up-Down

0.971 0.971 - - - - -

Mlig455_007030 {REF} {Length: 949} {RNA1509_30060} {RNA1310_40388.2, RNA1509_30060} {RNA1509_30060, RNA815_20453}

Mlig455_069136 {REF} {Length: 1235} {RNA1509_30060} {RNA1310_41028} {RNA815_20453}
11. MligTC455_25285 69 1.43 Mlig455_056009

Neo: -

Age: -

PCDH9 0.968 - 0.968 - - - - Mlig455_056009 {REF} {Length: 4817} {Pfam: Cadherin domain [PF00028.19, score=173.0]; Cadherin-like [PF16184.7, score=24.5]; Cadherin-like [PF08266.14, score=21.0]} {Human: ENSG00000184226, PCDH9, protocadherin 9, [Score=211, Expect=5e-55]} {Mouse: ENSMUSG00000055421, Pcdh9, protocadherin 9, [Score=211, Expect=2e-55]} {Dmel: FBgn0024836, stan, starry night, [Score=176, Expect=5e-44]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=143, Expect=3e-34]} {Smed: dd_Smed_v6_21207_0_1, dd_Smed_v6_21207_0_1, [RH, Score=294, Expect=1e-83]} {RNA1509_58565} {RNA1310_1772} {RNA815_3280}
12. MligTC455_41919 125 2.61 Mlig455_048053

Neo: -

Age: Up-Down-Up

Region-enriched R2: 4.173/0.00312

0.968 - 0.968 - - - - Mlig455_048053 {REF} {Length: 2537} {Pfam: Innexin [PF00876.20, score=331.0]} {Dmel: FBgn0265274, Inx3, Innexin 3, [Score=88.2, Expect=1e-18]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=254, Expect=8e-80]} {Smed: dd_Smed_v6_8019_0_1, dd_Smed_v6_8019_0_1, [Score=296, Expect=3e-95]} {RNA1509_58318} {RNA1310_9243} {RNA815_4486.1}
13. MligTC455_36925 236 4.92 Mlig455_049273

Neo: Int S/G2/M

Age: Down-Up-Up

RFX7 0.965 - 0.965 - - - - Mlig455_049273 {REF} {Length: 3627} {TRANSSPLICED} {Pfam: RFX DNA-binding domain [PF02257.17, score=94.5]; RFX5 N-terminal domain [PF18326.3, score=27.5]; Poxvirus D5 protein-like [PF03288.18, score=19.2]} {Human: ENSG00000181827, RFX7, regulatory factor X7, [RH, Score=139, Expect=4e-34]; ENSG00000143390, RFX5, regulatory factor X5, [RH, Score=139, Expect=1e-34]} {Mouse: ENSMUSG00000037674, Rfx7, regulatory factor X, 7, [RH, Score=166, Expect=3e-43]} {Dmel: FBgn0037445, CG9727, [RH, Score=155, Expect=1e-39]} {Celegans: WBGene00000914, daf-19, RFX-like transcription factor daf-19, [Score=65.5, Expect=6e-11]} {Smed: dd_Smed_v6_15486_0_1, dd_Smed_v6_15486_0_1, [Score=142, Expect=7e-37]} {RNA1509_24096} {RNA1310_12960, RNA1509_24096} {RNA1509_24096, RNA815_14577}
14. MligTC455_36926 232 4.83 Mlig455_050619

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.706

0.964 - 0.964 - - - - Mlig455_050619 {REF} {Length: 655} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_49677} {RNA815_29761}
15. MligTC455_40246 131 2.73 Mlig455_047354

Neo: -

Age: Up-Down-Down

Region-enriched R8: 4.326/0.00006
Region-enriched R7: 2.898/0.01364

0.964 0.964 - - - - - Mlig455_047354 {REF} {Length: 1853} {RNA1310_23716}
16. MligTC455_42952 1133 23.6 Mlig455_038557

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.656

Region-enriched R4: 1.639/0.00071

0.963 - 0.963 - - - - Mlig455_038557 {REF} {Length: 1484} {TRANSSPLICED} {Pfam: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial [PF15880.7, score=40.2]} {RNA1509_10373} {RNA1310_14044.2, RNA1509_10373} {RNA1509_10373, RNA815_9326.1}
17. MligTC455_42954 1129 23.53 Mlig455_053452

Neo: -

Age: -

Region-enriched R4: 1.661/0.00062

0.962 - 0.962 - - - - Mlig455_053452 {REF} {Length: 1459} {TRANSSPLICED} {RNA1509_10373} {RNA1310_14044.1} {RNA815_9326.1}
18. MligTC455_54231 270 5.62 Mlig455_059344

Neo: -

Age: logFC(26M/2M)=-0.427

0.962 - 0.962 - - - - Mlig455_059344 {REF} {Length: 1419} {RNA1310_28936} {RNA815_10014.1}
19. MligTC455_19672 631 13.14 Mlig455_043272

Neo: -

Age: -

0.961 - 0.961 - - - - Mlig455_043272 {REF} {Length: 2079} {TRANSSPLICED} {Pfam: BTB/POZ domain [PF00651.33, score=66.1]} {Mouse: ENSMUSG00000035941, Ibtk, inhibitor of Bruton agammaglobulinemia tyrosine kinase, [Score=50.1, Expect=4e-06]} {Dmel: FBgn0030961, CG7058, [Score=59.7, Expect=3e-09]} {Celegans: WBGene00018137, bath-41, BTB and MATH domain-containing protein 41, [Score=48.1, Expect=8e-06]} {Smed: dd_Smed_v6_7778_0_1, dd_Smed_v6_7778_0_1, [Score=73.9, Expect=4e-14]} {RNA1509_8768} {RNA1310_15058, RNA1509_8768} {RNA1509_8768, RNA815_8239}
20. MligTC455_48397 244 5.08 Mlig455_064477

Neo: -

Age: logFC(26M/2M)=-0.282

SCNN1G 0.961 0.961 - - - - - Mlig455_064477 {REF} {Length: 2621} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=238.2]} {Human: ENSG00000166828, SCNN1G, sodium channel epithelial 1 gamma subunit, [Score=81.6, Expect=1e-15]; ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=80.5, Expect=3e-15]} {Mouse: ENSMUSG00000000216, Scnn1g, sodium channel, nonvoltage-gated 1 gamma, [Score=86.7, Expect=2e-17]} {Celegans: WBGene00012137, asic-2, Degenerin-like protein asic-2, [Score=82.8, Expect=1e-16]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=125, Expect=3e-30]} {RNA1509_22321} {RNA1310_6593, RNA1509_22321} {RNA1509_22321, RNA815_4075}
21. MligTC455_21519 505 10.53 Mlig455_039816

Neo: -

Age: -

GHDC 0.959 0.959 - - - - - Mlig455_039816 {REF} {Length: 3759} {Pfam: GH3 auxin-responsive promoter [PF03321.15, score=390.4]} {Human: ENSG00000167925, GHDC, GH3 domain containing, [Score=72.0, Expect=2e-12]} {RNA1509_59400} {RNA1310_11058.1} {RNA815_4223.1}
22. MligTC455_47196 826 17.21 Mlig455_032049

Neo: -

Age: logFC(26M/2M)=-0.232

0.959 - - 0.959 - - - Mlig455_032049 {REF} {Length: 2910} {TRANSSPLICED} {Pfam: AN1-like Zinc finger [PF01428.18, score=22.3]} {RNA1509_32678, RNA1509_50490, RNA1509_59424} {RNA1310_5881, RNA1509_32678, RNA1509_50490, RNA1509_59424} {RNA1509_32678, RNA1509_50490, RNA1509_59424, RNA815_13594}
23. MligTC455_15784 370 7.7 Mlig455_029287

Neo: -

Age: -

0.958 - 0.958 - - - - Mlig455_029287 {REF} {Length: 1928} {Pfam: TIR domain [PF13676.8, score=46.2]} {Smed: dd_Smed_v6_13404_0_1, dd_Smed_v6_13404_0_1, [Score=112, Expect=2e-26]} {RNA1509_41551} {RNA1310_16315, RNA1509_41551} {RNA1509_41551, RNA815_7731}
24. MligTC455_15566 1057 22.03 Mlig455_004932, Mlig455_019726

Neo: -

Age: -

TOP2B 0.957 - 0.957 - - - -

Mlig455_004932 {REF} {Length: 4310} {TRANSSPLICED} {Pfam: DNA gyrase/topoisomerase IV, subunit A [PF00521.22, score=330.3]; C-terminal associated domain of TOPRIM [PF16898.7, score=70.3]; DNA gyrase B [PF00204.27, score=54.0]; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase [PF02518.28, score=45.7]} {Human: ENSG00000077097, TOP2B, DNA topoisomerase II beta, [Score=874, Expect=0.0]; ENSG00000131747, TOP2A, DNA topoisomerase II alpha, [Score=872, Expect=0.0]} {Mouse: ENSMUSG00000017485, Top2b, topoisomerase (DNA) II beta, [Score=878, Expect=0.0]; ENSMUSG00000020914, Top2a, topoisomerase (DNA) II alpha, [Score=876, Expect=0.0]} {Dmel: FBgn0284220, Top2, Topoisomerase 2, [Score=890, Expect=0.0]} {Celegans: WBGene00010785, top-2, Probable DNA topoisomerase 2, [Score=796, Expect=0.0]} {Smed: dd_Smed_v6_1626_0_3, dd_Smed_v6_1626_0_3, [Score=856, Expect=0.0]} {RNA1509_50365, RNA1509_8869} {RNA1310_2021, RNA1509_50365} {RNA1509_50365, RNA815_838}

Mlig455_019726 {REF} {Length: 4322} {TRANSSPLICED} {Pfam: DNA gyrase/topoisomerase IV, subunit A [PF00521.22, score=330.3]; C-terminal associated domain of TOPRIM [PF16898.7, score=70.3]; DNA gyrase B [PF00204.27, score=54.0]; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase [PF02518.28, score=44.4]} {Human: ENSG00000077097, TOP2B, DNA topoisomerase II beta, [Score=872, Expect=0.0]; ENSG00000131747, TOP2A, DNA topoisomerase II alpha, [Score=870, Expect=0.0]} {Mouse: ENSMUSG00000017485, Top2b, topoisomerase (DNA) II beta, [Score=875, Expect=0.0]; ENSMUSG00000020914, Top2a, topoisomerase (DNA) II alpha, [Score=874, Expect=0.0]} {Dmel: FBgn0284220, Top2, Topoisomerase 2, [Score=889, Expect=0.0]} {Celegans: WBGene00010785, top-2, Probable DNA topoisomerase 2, [Score=793, Expect=0.0]} {Smed: dd_Smed_v6_1626_0_3, dd_Smed_v6_1626_0_3, [Score=853, Expect=0.0]} {RNA1509_8869} {RNA1310_2021, RNA1509_8869} {RNA1509_8869, RNA815_838}
25. MligTC455_06002 108 2.24 Mlig455_067469

Neo: -

Age: -

CHRNA10 0.956 0.956 - - - - - Mlig455_067469 {REF} {Length: 3906} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=181.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=66.5]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=198, Expect=2e-57]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=193, Expect=9e-56]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=192, Expect=7e-55]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=199, Expect=6e-58]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=196, Expect=1e-56]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=192, Expect=1e-54]} {Celegans: WBGene00000043, acr-3, Acetylcholine receptor subunit beta-type acr-3, [Score=195, Expect=2e-56]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=226, Expect=3e-67]} {RNA1509_21945} {RNA1310_29351} {RNA815_3782.1}
26. MligTC455_08873 198 4.13 Mlig455_022707

Neo: -

Age: -

0.956 - 0.956 - - - - Mlig455_022707 {REF} {Length: 1291} {NoTransDecoderORF} {RNA1509_54108} {RNA1310_112068, RNA1509_54108} {RNA1509_54108, RNA815_23859}
27. MligTC455_05897 665 13.85 Mlig455_049059

Neo: -

Age: -

LNX2 0.955 - 0.955 - - - - Mlig455_049059 {REF} {Length: 6005} {TRANSSPLICED} {Pfam: PDZ domain [PF00595.26, score=182.6]; PDZ domain [PF17820.3, score=100.7]; PDZ domain [PF13180.8, score=57.3]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=27.9]; RING-type zinc-finger [PF13445.8, score=27.7]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=27.1]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=25.9]; TRAF-type zinc finger [PF02176.20, score=25.1]; zinc-RING finger domain [PF14634.8, score=22.9]; Ring finger domain [PF13639.8, score=22.5]; zinc finger of C3HC4-type, RING [PF15227.8, score=19.1]} {Human: ENSG00000139517, LNX2, ligand of numb-protein X 2, [Score=427, Expect=2e-138]} {Mouse: ENSMUSG00000016520, Lnx2, ligand of numb-protein X 2, [Score=416, Expect=3e-134]} {Dmel: FBgn0000008, a, arc, [RH, Score=70.9, Expect=4e-12]} {Celegans: WBGene00003404, mpz-1, Multiple PDZ domain protein, [Score=155, Expect=3e-40]} {Smed: dd_Smed_v6_8994_0_2, dd_Smed_v6_8994_0_2, [RH, Score=527, Expect=2e-175]} {RNA1509_14988} {RNA1310_9030} {RNA815_6198}
28. MligTC455_18701 462 9.62 Mlig455_002151

Neo: -

Age: -

RPS7 0.955 - 0.955 - - - - Mlig455_002151 {REF} {Length: 4747} {TRANSSPLICED} {Pfam: Ribosomal protein S7e [PF01251.20, score=189.9]; Major intrinsic protein [PF00230.22, score=18.7]} {Human: ENSG00000171863, RPS7, ribosomal protein S7, [Score=198, Expect=2e-60]} {Mouse: ENSMUSG00000061477, Rps7, ribosomal protein S7, [Score=198, Expect=2e-60]; ENSMUSG00000044424, Gm9493, predicted gene 9493, [Score=198, Expect=2e-60]} {Dmel: FBgn0039757, RpS7, Ribosomal protein S7, [Score=177, Expect=1e-52]} {Celegans: WBGene00004476, rps-7, 40S ribosomal protein S7, [Score=165, Expect=3e-48]} {Smed: dd_Smed_v6_204_0_1, dd_Smed_v6_204_0_1, [Score=156, Expect=6e-45]} {RNA1509_51916, RNA1509_53833} {RNA1310_2260.1, RNA1509_53833} {RNA1509_53833, RNA815_12689}
29. MligTC455_43571 239 4.99 Mlig455_037843

Neo: -

Age: Up-Down-Down

0.955 0.955 - - - - - Mlig455_037843 {REF} {Length: 2732} {RNA1509_10285, RNA1509_47003} {RNA1310_32269, RNA1509_10285} {RNA1509_10285, RNA815_20576}
30. MligTC455_54178 434 9.04 Mlig455_020796

Neo: -

Age: Down-Down-Up

Region-enriched R7: 1.941/0.00397

0.955 0.955 - - - - - Mlig455_020796 {REF} {Length: 2879} {Smed: dd_Smed_v6_5057_0_1, dd_Smed_v6_5057_0_1, [RH, Score=91.7, Expect=4e-20]} {RNA1509_10580} {RNA1310_9366, RNA1509_10580} {RNA1509_10580, RNA815_2566}
31. MligTC455_38554 131 2.72 Mlig455_038381

Neo: -

Age: logFC(26M/2M)=-0.458

DCHS2 0.954 0.954 - - - - - Mlig455_038381 {REF} {Length: 9031} {Pfam: Cadherin domain [PF00028.19, score=442.3]; Long Rib domain [PF18957.2, score=30.3]} {Human: ENSG00000197410, DCHS2, dachsous cadherin-related 2, [Score=387, Expect=1e-107]; ENSG00000166341, DCHS1, dachsous cadherin-related 1, [Score=387, Expect=2e-107]; ENSG00000284227, DCHS2, dachsous cadherin-related 2, [Score=387, Expect=1e-107]} {Mouse: ENSMUSG00000102692, Dchs2, dachsous cadherin related 2, [Score=400, Expect=1e-111]} {Dmel: FBgn0284247, ds, dachsous, [Score=341, Expect=1e-93]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=206, Expect=1e-52]} {Smed: dd_Smed_v6_11744_0_1, dd_Smed_v6_11744_0_1, [Score=209, Expect=1e-53]} {RNA1509_7140} {RNA1310_3117} {RNA815_267}
32. MligTC455_52585 294 6.12 Mlig455_045239

Neo: -

Age: -

ERICH3 0.954 0.954 - - - - - Mlig455_045239 {REF} {Length: 3780} {Pfam: Domain of unknown function (DUF4590) [PF15257.8, score=127.4]} {Human: ENSG00000178965, ERICH3, glutamate rich 3, [Score=119, Expect=2e-26]} {Mouse: ENSMUSG00000078161, Erich3, glutamate rich 3, [Score=117, Expect=5e-26]} {Smed: dd_Smed_v6_8627_0_1, dd_Smed_v6_8627_0_1, [Score=117, Expect=1e-26]} {RNA1509_55217} {RNA1310_4688.1} {RNA815_38425}
33. MligTC455_01388 150 3.13 Mlig455_009959

Neo: -

Age: Down-Up-Up

SOX14 0.953 - - - - - 0.953 Mlig455_009959 {REF} {Length: 2932} {Pfam: HMG (high mobility group) box [PF00505.21, score=95.1]; HMG-box domain [PF09011.12, score=40.0]} {Human: ENSG00000168875, SOX14, SRY-box 14, [RH, Score=182, Expect=7e-54]; ENSG00000125285, SOX21, SRY-box 21, [RH, Score=179, Expect=3e-52]} {Mouse: ENSMUSG00000053747, Sox14, SRY (sex determining region Y)-box 14, [RH, Score=182, Expect=5e-54]; ENSMUSG00000061517, Sox21, SRY (sex determining region Y)-box 21, [RH, Score=179, Expect=2e-52]} {Dmel: FBgn0042630, Sox21b, [RH, Score=174, Expect=5e-48]} {Celegans: WBGene00004950, sox-3, SOX (Mammalian SRY box) family, [RH, Score=169, Expect=2e-49]} {Smed: dd_Smed_v6_36521_0_1, dd_Smed_v6_36521_0_1, [RH, Score=179, Expect=7e-52]} {RNA1509_54582} {RNA1310_17227, RNA1509_54582} {RNA1509_54582, RNA815_15861.1}
34. MligTC455_26413 528 11.01 Mlig455_070891

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.372

EPS8 0.953 - - 0.953 - - - Mlig455_070891 {REF} {Length: 3874} {TRANSSPLICED} {Pfam: SH3 domain [PF00018.30, score=22.5]; Variant SH3 domain [PF07653.19, score=20.3]} {Human: ENSG00000151491, EPS8, epidermal growth factor receptor pathway substrate 8, [RH, Score=145, Expect=8e-37]} {Mouse: ENSMUSG00000015766, Eps8, epidermal growth factor receptor pathway substrate 8, [Score=154, Expect=3e-40]} {Dmel: FBgn0029095, aru, arouser, [RH, Score=140, Expect=4e-35]} {Celegans: WBGene00001330, eps-8, EPS (Human endocytosis) related; Epidermal growth factor receptor pathway substrate 8 splice variant A, [Score=204, Expect=4e-57]} {Smed: dd_Smed_v6_8993_0_1, dd_Smed_v6_8993_0_1, [RH, Score=74.3, Expect=6e-14]} {RNA1509_27030, RNA1509_45513, RNA1509_55389, RNA1509_59954, RNA1509_7172} {RNA1310_7150.1, RNA1509_27030, RNA1509_45513, RNA1509_55389, RNA1509_59954, RNA1509_7172} {RNA1509_27030, RNA1509_45513, RNA1509_55389, RNA1509_59954, RNA1509_7172, RNA815_2475.1}
35. MligTC455_43119 905 18.85 Mlig455_025240, Mlig455_025624

Neo: -

Age: -

0.953 - 0.953 - - - -

Mlig455_025240 {REF} {Length: 4336} {RNA1509_20151} {RNA1310_8688.1} {RNA815_9458.1}

Mlig455_025624 {REF} {Length: 4543} {RNA1509_20151} {RNA1310_8688.1} {RNA815_9458.1}
36. MligTC455_35480 129 2.68 Mlig455_020718

Neo: -

Age: -

SETMAR 0.952 - - 0.952 - - - Mlig455_020718 {REF} {Length: 1912} {TRANSSPLICED} {Pfam: HTH domain in Mos1 transposase [PF17906.3, score=32.2]; Winged helix-turn helix [PF13551.8, score=28.9]; Transposase [PF01498.20, score=28.8]; Homeodomain-like domain [PF13565.8, score=27.2]} {Human: ENSG00000170364, SETMAR, SET domain and mariner transposase fusion gene, [Score=68.9, Expect=5e-13]} {Smed: dd_Smed_v6_14929_0_1, dd_Smed_v6_14929_0_1, [RH, Score=66.6, Expect=3e-14]} {RNA1509_38392} {RNA1310_36448} {RNA815_24254}
37. MligTC455_39348 410 8.54 Mlig455_054310

Neo: -

Age: -

ERG 0.952 - - 0.952 - - - Mlig455_054310 {REF} {Length: 2524} {Pfam: Ets-domain [PF00178.24, score=93.5]} {Human: ENSG00000157554, ERG, ERG, ETS transcription factor, [Score=92.4, Expect=4e-20]; ENSG00000117036, ETV3, ETS variant 3, [Score=92.0, Expect=8e-20]; ENSG00000151702, FLI1, Fli-1 proto-oncogene, ETS transcription factor, [Score=90.1, Expect=2e-19]; ENSG00000253831, ETV3L, ETS variant 3 like, [Score=90.1, Expect=1e-19]; ENSG00000135373, EHF, ETS homologous factor, [Score=87.8, Expect=5e-19]} {Mouse: ENSMUSG00000040732, Erg, ETS transcription factor, [Score=92.4, Expect=3e-20]; ENSMUSG00000003382, Etv3, ets variant 3, [Score=91.7, Expect=6e-20]; ENSMUSG00000016087, Fli1, Friend leukemia integration 1, [Score=90.1, Expect=2e-19]} {Dmel: FBgn0005660, Ets21C, Ets at 21C, [Score=87.8, Expect=2e-19]} {Celegans: WBGene00016600, ets-5, ETS class transcription factor, [Score=87.0, Expect=6e-20]} {Smed: dd_Smed_v6_11113_0_1, dd_Smed_v6_11113_0_1, [Score=86.7, Expect=7e-19]} {RNA1509_27900, RNA1509_55575} {RNA1310_26221, RNA1509_27900} {RNA1509_27900, RNA815_19654}
38. MligTC455_41464 507 10.57 Mlig455_053551

Neo: -

Age: -

EIF2B1 0.952 - - 0.952 - - - Mlig455_053551 {REF} {Length: 6223} {TRANSSPLICED} {Pfam: Initiation factor 2 subunit family [PF01008.19, score=185.1]} {Human: ENSG00000111361, EIF2B1, eukaryotic translation initiation factor 2B subunit alpha, [Score=202, Expect=5e-58]} {Mouse: ENSMUSG00000029388, Eif2b1, eukaryotic translation initiation factor 2B, subunit 1 (alpha), [Score=208, Expect=2e-60]} {Dmel: FBgn0039726, eIF2Balpha, eukaryotic translation initiation factor 2B subunit alpha, [Score=216, Expect=1e-63]} {Celegans: WBGene00014221, eif-2Balpha, Probable translation initiation factor eIF-2B subunit alpha, [Score=192, Expect=5e-55]} {Smed: dd_Smed_v6_4682_0_1, dd_Smed_v6_4682_0_1, [Score=130, Expect=3e-33]} {RNA1509_30510, RNA1509_37474} {RNA1310_6473, RNA1509_30510} {RNA1509_30510, RNA815_14077}
39. MligTC455_23097 527 10.99 Mlig455_034804

Neo: -

Age: -

Region-enriched R7: 1.584/0.03995

HPCA 0.95 - - 0.950 - - - Mlig455_034804 {REF} {Length: 5504} {Pfam: EF hand [PF00036.34, score=45.5]; EF-hand domain pair [PF13499.8, score=44.0]; EF-hand domain [PF13405.8, score=38.4]; EF hand [PF13202.8, score=37.1]; EF-hand domain pair [PF13833.8, score=24.8]} {Human: ENSG00000121905, HPCA, hippocalcin, [Score=75.9, Expect=2e-18]; ENSG00000104490, NCALD, neurocalcin delta, [Score=75.5, Expect=4e-18]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=75.5, Expect=4e-18]} {Mouse: ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=76.6, Expect=1e-18]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=75.9, Expect=1e-18]; ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=75.5, Expect=3e-18]} {Dmel: FBgn0036926, CG7646, [RH, Score=82.0, Expect=3e-22]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=83.2, Expect=1e-21]} {Smed: dd_Smed_v6_6534_0_2, dd_Smed_v6_6534_0_2, [Score=145, Expect=6e-46]} {RNA1509_31370} {RNA1310_35758, RNA1509_31370} {RNA1509_31370, RNA815_25037}
40. MligTC455_27923 318 6.64 Mlig455_037735

Neo: -

Age: -

0.95 - - 0.950 - - - Mlig455_037735 {REF} {Length: 2740} {Pfam: Noggin [PF05806.14, score=33.9]} {Smed: dd_Smed_v6_7999_0_1, dd_Smed_v6_7999_0_1, [Score=77.4, Expect=1e-16]} {RNA1509_58515} {RNA1310_28925, RNA1509_58515} {RNA1509_58515, RNA815_419.1}
41. MligTC455_28986 256 5.33 Mlig455_059441

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.429

0.95 - - 0.950 - - - Mlig455_059441 {REF} {Length: 1071} {TRANSSPLICED} {RNA1509_45862} {RNA1310_33199, RNA1509_45862} {RNA1509_45862, RNA815_15931}
42. MligTC455_43572 61 1.26 Mlig455_037945

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.663

VCX3B 0.95 0.950 - - - - - Mlig455_037945 {REF} {Length: 2194} {Human: ENSG00000205642, VCX3B, variable charge X-linked 3B, [Score=54.7, Expect=8e-09]} {RNA1509_22457} {RNA1310_35286} {RNA815_20576}
43. MligTC455_44381 50 1.04 Mlig455_034187

Neo: -

Age: -

0.95 - - 0.950 - - - Mlig455_034187 {REF} {Length: 1133} {Pfam: WSC domain [PF01822.21, score=41.3]} {RNA1310_44307} {RNA815_33128}
44. MligTC455_47088 3826 79.71 Mlig455_027638

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.552

Region-enriched R8: 6.838/0.00000
Region-enriched R7: 4.443/0.00000

CALML6 0.95 0.950 - - - - - Mlig455_027638 {REF} {Length: 788} {Pfam: EF-hand domain pair [PF13499.8, score=77.1]; EF hand [PF00036.34, score=76.3]; EF-hand domain [PF13405.8, score=63.9]; EF hand [PF13202.8, score=54.2]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=31.3]; EF-hand domain [PF14658.8, score=25.9]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=23.3]; EF-hand domain pair [PF13833.8, score=21.6]} {Human: ENSG00000169885, CALML6, calmodulin like 6, [Score=53.9, Expect=8e-09]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=52.4, Expect=2e-08]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=50.8, Expect=5e-08]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=50.8, Expect=5e-08]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=50.4, Expect=6e-08]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=48.1, Expect=3e-07]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=50.4, Expect=5e-08]} {Smed: dd_Smed_v6_299_0_1, dd_Smed_v6_299_0_1, [RH, Score=99.8, Expect=4e-27]} {RNA1509_8844} {RNA1310_30724} {RNA815_14702}
45. MligTC455_49779 553 11.53 Mlig455_041274

Neo: -

Age: -

RASGEF1B 0.95 - 0.950 - - - - Mlig455_041274 {REF} {Length: 2602} {TRANSSPLICED} {Pfam: RasGEF domain [PF00617.21, score=119.1]; RasGEF N-terminal motif [PF00618.22, score=26.1]} {Human: ENSG00000138670, RASGEF1B, RasGEF domain family member 1B, [RH, Score=292, Expect=5e-94]} {Mouse: ENSMUSG00000089809, Rasgef1b, RasGEF domain family, member 1B, [RH, Score=291, Expect=9e-94]} {Dmel: FBgn0037188, CG7369, [RH, Score=192, Expect=3e-54]} {Celegans: WBGene00019902, R05G6.10, [RH, Score=196, Expect=2e-57]} {RNA1509_13449, RNA1509_33255, RNA1509_49132, RNA1509_57997} {RNA1310_20170, RNA1509_13449, RNA1509_33255, RNA1509_49132, RNA1509_57997} {RNA1509_13449, RNA1509_33255, RNA1509_49132, RNA1509_57997, RNA815_15138}

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