Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_07033 | 517 | 10.77 | Mlig455_051183 | Neo: - Age: - |
DCUN1D3 | Mlig455_051183 {REF} {Length: 2223} {TRANSSPLICED} {Pfam: Cullin binding [PF03556.17, score=102.2]} {Human: ENSG00000188215, DCUN1D3, defective in cullin neddylation 1 domain containing 3, [RH, Score=156, Expect=1e-45]} {Mouse: ENSMUSG00000048787, Dcun1d3, DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae), [RH, Score=157, Expect=6e-46]} {Dmel: FBgn0033784, SCCRO3, Squamous cell carcinoma-related oncogene 3, [RH, Score=149, Expect=7e-43]} {Celegans: WBGene00010428, dcn-1, Defective in cullin neddylation protein 1, [Score=90.9, Expect=1e-21]} {Smed: dd_Smed_v6_3227_0_1, dd_Smed_v6_3227_0_1, [Score=90.1, Expect=2e-21]} {RNA1509_47536} {RNA1310_18793.1, RNA1509_47536} {RNA1509_47536, RNA815_23221} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 0.82 | 3.757 | 0.42992 | 1.00000 | |
RegionR2 | -0.081 | 3.757 | 0.85954 | 1.00000 | |
RegionR3 | -0.715 | 3.757 | 0.06875 | 0.46358 | |
RegionR4 | 0.096 | 3.757 | 0.80514 | 1.00000 | |
RegionR5 | 0.277 | 3.757 | 0.36573 | 0.71829 | |
RegionR6 | 0.172 | 3.757 | 0.63671 | 1.00000 | |
RegionR7 | -0.486 | 3.757 | 0.40697 | 1.00000 | |
RegionR8 | -0.084 | 3.757 | 0.90947 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -7.813 | 3.757 | 0.03457 | 0.64695 | |
RegenerationR2 | 0.32 | 3.757 | 0.32468 | 0.76278 | |
RegenerationR3 | 0.471 | 3.757 | 0.24277 | 0.67753 | |
RegenerationR4 | -0.085 | 3.757 | 0.81256 | 0.99043 | |
RegenerationR5 | -0.281 | 3.757 | 0.37869 | 0.78637 | |
RegenerationR6 | 0.203 | 3.757 | 0.57791 | 0.85655 | |
RegenerationBL | 0.503 | 3.757 | 0.31596 | 0.68261 | |
RegenerationTP | -0.647 | 3.757 | 0.35597 | 0.79702 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_07033 | 517 | 10.77 | Mlig455_051183 | Neo: - Age: - |
DCUN1D3 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_051183 {REF} {Length: 2223} {TRANSSPLICED} {Pfam: Cullin binding [PF03556.17, score=102.2]} {Human: ENSG00000188215, DCUN1D3, defective in cullin neddylation 1 domain containing 3, [RH, Score=156, Expect=1e-45]} {Mouse: ENSMUSG00000048787, Dcun1d3, DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae), [RH, Score=157, Expect=6e-46]} {Dmel: FBgn0033784, SCCRO3, Squamous cell carcinoma-related oncogene 3, [RH, Score=149, Expect=7e-43]} {Celegans: WBGene00010428, dcn-1, Defective in cullin neddylation protein 1, [Score=90.9, Expect=1e-21]} {Smed: dd_Smed_v6_3227_0_1, dd_Smed_v6_3227_0_1, [Score=90.1, Expect=2e-21]} {RNA1509_47536} {RNA1310_18793.1, RNA1509_47536} {RNA1509_47536, RNA815_23221} |
2. | MligTC455_15602 | 268 | 5.57 | Mlig455_042253 | Neo: - Age: logFC(26M/2M)=-0.631 Region-enriched R4: 2.225/0.04268 |
CASP3 | 1.733 | - | - | - | 0.780 | 0.953 | - | Mlig455_042253 {REF} {Length: 1874} {Pfam: Caspase domain [PF00656.24, score=103.2]; Ankyrin repeats (3 copies) [PF12796.9, score=42.9]; Ankyrin repeats (many copies) [PF13857.8, score=36.2]; Ankyrin repeats (many copies) [PF13637.8, score=31.3]; Ankyrin repeat [PF13606.8, score=24.2]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=122, Expect=2e-31]; ENSG00000165806, CASP7, caspase 7, [Score=121, Expect=2e-30]} {Mouse: ENSMUSG00000025076, Casp7, caspase 7, [Score=122, Expect=2e-31]; ENSMUSG00000031628, Casp3, caspase 3, [Score=119, Expect=3e-30]} {Dmel: FBgn0026404, Dronc, Death regulator Nedd2-like caspase, [RH, Score=98.6, Expect=4e-22]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=92.0, Expect=9e-21]} {Smed: dd_Smed_v6_1167_0_1, dd_Smed_v6_1167_0_1, [Score=134, Expect=1e-36]} {RNA1509_39319} {RNA1310_43842} {RNA815_7180.1} |
3. | MligTC455_25321 | 318 | 6.62 | Mlig455_064863 | Neo: - Age: - |
SOCS7 | 1.72 | - | - | - | 0.956 | - | 0.764 | Mlig455_064863 {REF} {Length: 4577} {TRANSSPLICED} {Pfam: SH2 domain [PF00017.26, score=47.9]; SOCS box [PF07525.18, score=34.3]} {Human: ENSG00000274229, SOCS7, suppressor of cytokine signaling 7, [RH, Score=180, Expect=4e-48]; ENSG00000274211, SOCS7, suppressor of cytokine signaling 7, [RH, Score=180, Expect=4e-48]} {Mouse: ENSMUSG00000038485, Socs7, suppressor of cytokine signaling 7, [Score=179, Expect=8e-48]} {Dmel: FBgn0030869, Socs16D, Suppressor of Cytokine Signaling at 16D, [RH, Score=160, Expect=2e-40]} {Celegans: WBGene00009556, F39B2.5, [RH, Score=67.8, Expect=9e-13]} {Smed: dd_Smed_v6_489_0_3, dd_Smed_v6_489_0_3, [RH, Score=232, Expect=3e-64]} {RNA1509_15003, RNA1509_35397} {RNA1310_19350, RNA1509_35397} {RNA1509_35397, RNA815_16941.1} |
4. | MligTC455_34706 | 1472 | 30.67 | Mlig455_059159, Mlig455_065531 | Neo: - Age: - |
AGO2 | 0.965 | - | - | - | - | 0.965 | - | Mlig455_059159 {REF} {Length: 7005} {Pfam: Piwi domain [PF02171.19, score=363.8]; Mid domain of argonaute [PF16487.7, score=113.6]; N-terminal domain of argonaute [PF16486.7, score=92.1]; PAZ domain [PF02170.24, score=81.0]; Argonaute linker 1 domain [PF08699.12, score=78.2]; Argonaute linker 2 domain [PF16488.7, score=52.0]} {Human: ENSG00000123908, AGO2, argonaute 2, RISC catalytic component, [RH, Score=1248, Expect=0.0]; ENSG00000092847, AGO1, argonaute 1, RISC catalytic component, [RH, Score=1230, Expect=0.0]; ENSG00000126070, AGO3, argonaute 3, RISC catalytic component, [RH, Score=1220, Expect=0.0]; ENSG00000134698, AGO4, argonaute 4, RISC catalytic component, [RH, Score=1201, Expect=0.0]} {Mouse: ENSMUSG00000036698, Ago2, argonaute RISC catalytic subunit 2, [RH, Score=1251, Expect=0.0]; ENSMUSG00000041530, Ago1, argonaute RISC catalytic subunit 1, [RH, Score=1230, Expect=0.0]; ENSMUSG00000028842, Ago3, argonaute RISC catalytic subunit 3, [RH, Score=1218, Expect=0.0]; ENSMUSG00000042500, Ago4, argonaute RISC catalytic subunit 4, [RH, Score=1200, Expect=0.0]} {Dmel: FBgn0262739, AGO1, Argonaute-1, [RH, Score=1323, Expect=0.0]} {Celegans: WBGene00000105, alg-1, Argonaute-like, [RH, Score=1245, Expect=0.0]} {Smed: dd_Smed_v6_3861_0_1, dd_Smed_v6_3861_0_1, [RH, Score=1427, Expect=0.0]} {RNA1509_19989, RNA1509_34423, RNA1509_53824} {RNA1310_7009, RNA1509_19989, RNA1509_34423, RNA1509_53824} {RNA1509_19989, RNA1509_34423, RNA1509_53824, RNA815_1509.1} Mlig455_065531 {REF} {Length: 7345} {Pfam: Piwi domain [PF02171.19, score=364.9]; Mid domain of argonaute [PF16487.7, score=113.6]; N-terminal domain of argonaute [PF16486.7, score=92.2]; PAZ domain [PF02170.24, score=81.0]; Argonaute linker 1 domain [PF08699.12, score=78.2]; Argonaute linker 2 domain [PF16488.7, score=51.9]} {Human: ENSG00000123908, AGO2, argonaute 2, RISC catalytic component, [RH, Score=1249, Expect=0.0]; ENSG00000092847, AGO1, argonaute 1, RISC catalytic component, [RH, Score=1230, Expect=0.0]; ENSG00000126070, AGO3, argonaute 3, RISC catalytic component, [RH, Score=1221, Expect=0.0]; ENSG00000134698, AGO4, argonaute 4, RISC catalytic component, [RH, Score=1203, Expect=0.0]} {Mouse: ENSMUSG00000036698, Ago2, argonaute RISC catalytic subunit 2, [RH, Score=1252, Expect=0.0]; ENSMUSG00000041530, Ago1, argonaute RISC catalytic subunit 1, [RH, Score=1230, Expect=0.0]; ENSMUSG00000028842, Ago3, argonaute RISC catalytic subunit 3, [RH, Score=1219, Expect=0.0]; ENSMUSG00000042500, Ago4, argonaute RISC catalytic subunit 4, [RH, Score=1201, Expect=0.0]} {Dmel: FBgn0262739, AGO1, Argonaute-1, [RH, Score=1323, Expect=0.0]} {Celegans: WBGene00000105, alg-1, Argonaute-like, [RH, Score=1245, Expect=0.0]} {Smed: dd_Smed_v6_3861_0_1, dd_Smed_v6_3861_0_1, [RH, Score=1427, Expect=0.0]} {RNA1509_15818, RNA1509_28180, RNA1509_34423} {RNA1310_7009, RNA1509_15818, RNA1509_28180} {RNA1509_15818, RNA1509_28180, RNA815_1509.1} |
5. | MligTC455_43360 | 1399 | 29.14 | Mlig455_056691 | Neo: - Age: - |
0.962 | - | - | - | - | 0.962 | - | Mlig455_056691 {REF} {Length: 438} {TRANSSPLICED} {RNA1509_9309} {RNA1310_53418} {RNA815_23198.2} | |
6. | MligTC455_26656 | 215 | 4.48 | Mlig455_067721 | Neo: - Age: - |
0.96 | - | - | - | - | - | 0.960 | Mlig455_067721 {REF} {Length: 3295} {Pfam: Domain of unknown function (DUF1868) [PF08975.12, score=30.6]} {RNA1509_48474} {RNA1310_38237, RNA1509_48474} {RNA1509_48474, RNA815_31773} | |
7. | MligTC455_19076 | 464 | 9.68 | Mlig455_034432 | Neo: - Age: - |
IYD | 0.959 | - | - | 0.959 | - | - | - | Mlig455_034432 {REF} {Length: 2170} {TRANSSPLICED} {Pfam: Nitroreductase family [PF00881.26, score=68.1]} {Human: ENSG00000009765, IYD, iodotyrosine deiodinase, [RH, Score=232, Expect=4e-73]} {Mouse: ENSMUSG00000019762, Iyd, iodotyrosine deiodinase, [RH, Score=232, Expect=2e-73]} {Dmel: FBgn0036125, Iyd, Iodotyrosine deiodinase, [RH, Score=206, Expect=5e-59]} {Celegans: WBGene00015334, sup-18, Iodotyrosine dehalogenase 1 homolog, [RH, Score=187, Expect=6e-56]} {RNA1509_12445, RNA1509_24516} {RNA1310_15230, RNA1509_12445, RNA1509_24516} {RNA1509_12445, RNA1509_24516, RNA815_4797} |
8. | MligTC455_49655 | 957 | 19.94 | Mlig455_002453, Mlig455_002720 | Neo: - Age: logFC(26M/2M)=0.337 Regeneration-upregulated BL: 1.810 Regeneration-enriched BL: 1.810 |
UAP1 | 0.957 | - | - | 0.957 | - | - | - | Mlig455_002453 {REF} {Length: 2391} {TRANSSPLICED} {Pfam: UTP--glucose-1-phosphate uridylyltransferase [PF01704.20, score=131.3]} {Human: ENSG00000117143, UAP1, UDP-N-acetylglucosamine pyrophosphorylase 1, [Score=327, Expect=2e-106]; ENSG00000197355, UAP1L1, UDP-N-acetylglucosamine pyrophosphorylase 1 like 1, [Score=315, Expect=1e-101]} {Mouse: ENSMUSG00000026670, Uap1, UDP-N-acetylglucosamine pyrophosphorylase 1, [Score=339, Expect=3e-111]} {Dmel: FBgn0259749, mmy, mummy, [RH, Score=349, Expect=6e-115]} {Celegans: WBGene00007965, C36A4.4, Probable UDP-N-acetylglucosamine pyrophosphorylase, [RH, Score=239, Expect=4e-73]} {Smed: dd_Smed_v6_2150_1_1, dd_Smed_v6_2150_1_1, [Score=343, Expect=4e-113]} {RNA1509_18328} {RNA1310_8742, RNA1509_18328} {RNA1509_18328, RNA815_10366} Mlig455_002720 {REF} {Length: 2405} {Pfam: UTP--glucose-1-phosphate uridylyltransferase [PF01704.20, score=131.3]} {Human: ENSG00000117143, UAP1, UDP-N-acetylglucosamine pyrophosphorylase 1, [Score=327, Expect=2e-106]; ENSG00000197355, UAP1L1, UDP-N-acetylglucosamine pyrophosphorylase 1 like 1, [Score=313, Expect=7e-101]} {Mouse: ENSMUSG00000026670, Uap1, UDP-N-acetylglucosamine pyrophosphorylase 1, [Score=340, Expect=2e-111]} {Dmel: FBgn0259749, mmy, mummy, [Score=348, Expect=2e-115]} {Celegans: WBGene00007965, C36A4.4, Probable UDP-N-acetylglucosamine pyrophosphorylase, [Score=237, Expect=2e-72]} {Smed: dd_Smed_v6_2150_1_1, dd_Smed_v6_2150_1_1, [Score=348, Expect=2e-115]} {RNA1509_18328} {RNA1310_8742} {RNA815_10366} |
9. | MligTC455_44946 | 83 | 1.73 | Mlig455_046261, Mlig455_066038 | Neo: Irradiation Age: Up-Down-Down Region-enriched R4: 5.905/0.02618 |
POLQ, PRR9 | 0.955 | - | - | - | - | - | 0.955 | Mlig455_046261 {REF} {Length: 9223} {TRANSSPLICED} {Pfam: DNA polymerase family A [PF00476.22, score=307.8]; Helicase conserved C-terminal domain [PF00271.33, score=41.2]; DEAD/DEAH box helicase [PF00270.31, score=22.4]} {Human: ENSG00000051341, POLQ, DNA polymerase theta, [RH, Score=610, Expect=5e-178]} {Mouse: ENSMUSG00000034206, Polq, polymerase (DNA directed), theta, [RH, Score=613, Expect=2e-179]} {Dmel: FBgn0002905, mus308, mutagen-sensitive 308, [RH, Score=575, Expect=7e-169]} {Celegans: WBGene00020964, polq-1, DNA polymerase theta, [RH, Score=308, Expect=3e-84]} {Smed: dd_Smed_v6_51730_0_3, dd_Smed_v6_51730_0_3, [RH, Score=253, Expect=8e-76]} {RNA1509_38802} {RNA1310_1092} {RNA815_20127} Mlig455_066038 {REF} {Length: 1082} {Human: ENSG00000203783, PRR9, proline rich 9, [Score=42.4, Expect=1e-05]} {RNA1310_62396} |
10. | MligTC455_19607 | 1234 | 25.71 | Mlig455_011666 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=-0.549 Region-enriched R4: 2.696/0.00001 |
NOTCH1 | 0.954 | - | - | 0.954 | - | - | - | Mlig455_011666 {REF} {Length: 1856} {Pfam: EGF-like domain [PF00008.29, score=24.4]} {Human: ENSG00000148400, NOTCH1, notch 1, [Score=64.7, Expect=1e-10]} {Mouse: ENSMUSG00000026923, Notch1, notch 1, [Score=65.1, Expect=6e-11]; ENSMUSG00000038146, Notch3, notch 3, [Score=63.9, Expect=1e-10]} {Dmel: FBgn0004647, N, Notch, [Score=57.8, Expect=1e-08]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=57.8, Expect=6e-09]} {RNA1509_35808} {RNA1310_45966} {RNA815_17030.1} |
11. | MligTC455_43213 | 450 | 9.38 | Mlig455_041657 | Neo: - Age: - |
BECN1 | 0.953 | - | - | - | - | - | 0.953 | Mlig455_041657 {REF} {Length: 3339} {TRANSSPLICED} {Pfam: Apg6 BARA domain [PF04111.14, score=136.6]; Apg6 coiled-coil region [PF17675.3, score=58.2]} {Human: ENSG00000126581, BECN1, beclin 1, [RH, Score=205, Expect=3e-60]} {Mouse: ENSMUSG00000035086, Becn1, beclin 1, autophagy related, [RH, Score=202, Expect=1e-59]} {Dmel: FBgn0264325, Atg6, Autophagy-related 6, [RH, Score=187, Expect=3e-54]} {Celegans: WBGene00000247, bec-1, Beclin homolog, [RH, Score=117, Expect=9e-29]} {Smed: dd_Smed_v6_5353_0_1, dd_Smed_v6_5353_0_1, [RH, Score=180, Expect=2e-51]} {RNA1509_16640, RNA1509_27883, RNA1509_51377} {RNA1310_18844, RNA1509_16640, RNA1509_27883, RNA1509_51377} {RNA1509_16640, RNA1509_27883, RNA1509_51377, RNA815_7657} |
12. | MligTC455_28017 | 212 | 4.42 | Mlig455_022438 | Neo: - Age: Up-Down-Down |
0.952 | - | - | - | 0.952 | - | - | Mlig455_022438 {REF} {Length: 508} {NoTransDecoderORF} {RNA1509_3} {RNA1310_851.1} {RNA815_80.1} |