Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_15173 | 297 | 6.19 | Mlig455_056349 | Neo: - Age: - |
GAB3 | Mlig455_056349 {REF} {Length: 4339} {TRANSSPLICED} {Pfam: PH domain [PF00169.31, score=44.1]} {Human: ENSG00000160219, GAB3, GRB2 associated binding protein 3, [RH, Score=59.7, Expect=1e-08]; ENSG00000109458, GAB1, GRB2 associated binding protein 1, [RH, Score=58.9, Expect=2e-08]} {Mouse: ENSMUSG00000032750, Gab3, growth factor receptor bound protein 2-associated protein 3, [RH, Score=55.1, Expect=2e-07]} {Dmel: FBgn0016794, dos, daughter of sevenless, [RH, Score=56.2, Expect=7e-08]} {Smed: dd_Smed_v6_8815_0_1, dd_Smed_v6_8815_0_1, [RH, Score=50.8, Expect=2e-06]} {RNA1509_32308} {RNA1310_20098} {RNA815_10250} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 1.207 | 3.191 | 0.56446 | 1.00000 | |
RegionR2 | 0.352 | 3.191 | 0.62534 | 0.96781 | |
RegionR3 | 1.221 | 3.191 | 0.11930 | 0.59764 | |
RegionR4 | 1.708 | 3.191 | 0.06568 | 0.23186 | |
RegionR5 | 1.098 | 3.191 | 0.15135 | 0.40542 | |
RegionR6 | 0.344 | 3.191 | 0.61618 | 1.00000 | |
RegionR7 | -0.58 | 3.191 | 0.94926 | 1.00000 | |
RegionR8 | -5.351 | 3.191 | 0.07679 | 0.52804 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -5.586 | 3.191 | 0.34376 | 1.00000 | |
RegenerationR2 | 1.032 | 3.191 | 0.06942 | 0.42928 | |
RegenerationR3 | 0.127 | 3.191 | 0.84872 | 0.99812 | |
RegenerationR4 | 0.789 | 3.191 | 0.26209 | 0.70987 | |
RegenerationR5 | 1.302 | 3.191 | 0.02918 | 0.28752 | |
RegenerationR6 | 1.899 | 3.191 | 0.00463 | 0.08220 | |
RegenerationBL | 3.778 | 3.191 | 0.00049 | 0.01380 | |
RegenerationTP | 3.849 | 3.191 | 0.02219 | 0.25359 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_15173 | 297 | 6.19 | Mlig455_056349 | Neo: - Age: - |
GAB3 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_056349 {REF} {Length: 4339} {TRANSSPLICED} {Pfam: PH domain [PF00169.31, score=44.1]} {Human: ENSG00000160219, GAB3, GRB2 associated binding protein 3, [RH, Score=59.7, Expect=1e-08]; ENSG00000109458, GAB1, GRB2 associated binding protein 1, [RH, Score=58.9, Expect=2e-08]} {Mouse: ENSMUSG00000032750, Gab3, growth factor receptor bound protein 2-associated protein 3, [RH, Score=55.1, Expect=2e-07]} {Dmel: FBgn0016794, dos, daughter of sevenless, [RH, Score=56.2, Expect=7e-08]} {Smed: dd_Smed_v6_8815_0_1, dd_Smed_v6_8815_0_1, [RH, Score=50.8, Expect=2e-06]} {RNA1509_32308} {RNA1310_20098} {RNA815_10250} |
2. | MligTC455_36401 | 1090 | 22.72 | Mlig455_064321 | Neo: Int S/G2/M Age: Down-Up-Down |
0.967 | - | - | - | 0.967 | - | - | Mlig455_064321 {REF} {Length: 2091} {TRANSSPLICED} {RNA1509_29392} {RNA1310_10833} {RNA815_3918} | |
3. | MligTC455_27797 | 878 | 18.29 | Mlig455_032097 | Neo: Int S/G2/M Age: Down-Down-Up |
HGH1 | 0.965 | - | - | - | 0.965 | - | - | Mlig455_032097 {REF} {Length: 1661} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF383) [PF04063.16, score=61.7]; Domain of unknown function (DUF384) [PF04064.15, score=46.9]} {Human: ENSG00000235173, HGH1, HGH1 homolog, [RH, Score=107, Expect=3e-25]} {Mouse: ENSMUSG00000022554, Hgh1, HGH1 homolog, [RH, Score=100, Expect=6e-23]} {Celegans: WBGene00021900, Y54H5A.2, [Score=58.2, Expect=3e-09]} {RNA1509_20599} {RNA1310_524.1, RNA1509_20599} {RNA1509_20599, RNA815_9894.1} |
4. | MligTC455_34361 | 4426 | 92.21 | Mlig455_025291, Mlig455_025317 | Neo: Neoblast, stringent Age: Down-Up-Down Region-enriched R5: 1.390/0.00001 |
PCNA | 0.959 | - | - | - | 0.959 | - | - | Mlig455_025291 {REF} {Length: 1283} {TRANSSPLICED} {Pfam: Proliferating cell nuclear antigen, N-terminal domain [PF00705.20, score=180.6]; Proliferating cell nuclear antigen, C-terminal domain [PF02747.17, score=176.9]; Rad9 [PF04139.15, score=39.8]; Repair protein Rad1/Rec1/Rad17 [PF02144.18, score=28.2]; Hus1-like protein [PF04005.14, score=19.8]} {Human: ENSG00000132646, PCNA, proliferating cell nuclear antigen, [RH, Score=359, Expect=8e-126]} {Mouse: ENSMUSG00000027342, Pcna, proliferating cell nuclear antigen, [RH, Score=360, Expect=2e-126]; ENSMUSG00000067608, Pcna-ps2, proliferating cell nuclear antigen pseudogene 2, [RH, Score=360, Expect=1e-126]} {Dmel: FBgn0005655, PCNA, Proliferating cell nuclear antigen, [RH, Score=348, Expect=1e-121]} {Celegans: WBGene00003955, pcn-1, Proliferating cell nuclear antigen, [RH, Score=259, Expect=7e-87]} {Smed: dd_Smed_v6_1920_0_1, dd_Smed_v6_1920_0_1, [RH, Score=373, Expect=9e-132]} {RNA1509_20905} {RNA1310_24951.1} {RNA815_11580.1} Mlig455_025317 {REF} {Length: 1281} {TRANSSPLICED} {Pfam: Proliferating cell nuclear antigen, N-terminal domain [PF00705.20, score=180.6]; Proliferating cell nuclear antigen, C-terminal domain [PF02747.17, score=176.9]; Rad9 [PF04139.15, score=39.8]; Repair protein Rad1/Rec1/Rad17 [PF02144.18, score=28.2]; Hus1-like protein [PF04005.14, score=19.8]} {Human: ENSG00000132646, PCNA, proliferating cell nuclear antigen, [RH, Score=359, Expect=8e-126]} {Mouse: ENSMUSG00000027342, Pcna, proliferating cell nuclear antigen, [RH, Score=360, Expect=2e-126]; ENSMUSG00000067608, Pcna-ps2, proliferating cell nuclear antigen pseudogene 2, [RH, Score=360, Expect=1e-126]} {Dmel: FBgn0005655, PCNA, Proliferating cell nuclear antigen, [RH, Score=348, Expect=1e-121]} {Celegans: WBGene00003955, pcn-1, Proliferating cell nuclear antigen, [RH, Score=259, Expect=7e-87]} {Smed: dd_Smed_v6_1920_0_1, dd_Smed_v6_1920_0_1, [RH, Score=373, Expect=9e-132]} {RNA1509_20905} {RNA1310_24951.1} {RNA815_11580.1} |
5. | MligTC455_07314 | 687 | 14.32 | Mlig455_000525 | Neo: Irradiation Age: - Region-enriched R5: 1.319/0.00385 |
SIN3B | 0.957 | - | - | - | 0.957 | - | - | Mlig455_000525 {REF} {Length: 4206} {TRANSSPLICED} {Pfam: C-terminal domain of Sin3a protein [PF16879.7, score=97.0]} {Human: ENSG00000127511, SIN3B, SIN3 transcription regulator family member B, [Score=186, Expect=1e-48]} {Mouse: ENSMUSG00000031622, Sin3b, transcriptional regulator, SIN3B (yeast), [Score=196, Expect=3e-52]} {Dmel: FBgn0022764, Sin3A, [Score=147, Expect=2e-36]} {Smed: dd_Smed_v6_7034_0_1, dd_Smed_v6_7034_0_1, [Score=97.4, Expect=9e-21]} {RNA1509_4899} {RNA1310_4266.2} {RNA815_1997} |
6. | MligTC455_36402 | 1006 | 20.97 | Mlig455_064351 | Neo: - Age: - |
0.957 | - | - | - | 0.957 | - | - | Mlig455_064351 {REF} {Length: 2238} {TRANSSPLICED} {RNA1509_29392, RNA1509_6010} {RNA1310_7162, RNA1509_29392, RNA1509_6010} {RNA1509_29392, RNA1509_6010, RNA815_3918} | |
7. | MligTC455_24022 | 1386 | 28.87 | Mlig455_058748 | Neo: - Age: Down-Up-Down |
CTDSP1 | 0.955 | - | - | - | 0.955 | - | - | Mlig455_058748 {REF} {Length: 2724} {Pfam: NLI interacting factor-like phosphatase [PF03031.20, score=160.5]} {Human: ENSG00000144579, CTDSP1, CTD small phosphatase 1, [RH, Score=248, Expect=5e-81]} {Mouse: ENSMUSG00000026176, Ctdsp1, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1, [RH, Score=246, Expect=9e-81]; ENSMUSG00000047409, Ctdspl, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like, [RH, Score=238, Expect=2e-77]} {Dmel: FBgn0036556, CG5830, [RH, Score=232, Expect=5e-74]} {Celegans: WBGene00007054, scpl-1, CTD small phosphatase-like protein 1, [RH, Score=226, Expect=3e-70]} {Smed: dd_Smed_v6_8196_0_1, dd_Smed_v6_8196_0_1, [RH, Score=251, Expect=1e-77]} {RNA1509_16095, RNA1509_9752} {RNA1310_7374.1, RNA1509_16095, RNA1509_9752} {RNA1509_16095, RNA1509_9752, RNA815_2431} |
8. | MligTC455_07315 | 1412 | 29.41 | Mlig455_000426, Mlig455_024855 | Neo: - Age: - Region-enriched R5: 1.338/0.00399 |
SIN3A, SIN3B | 0.954 | - | - | - | 0.954 | - | - | Mlig455_000426 {REF} {Length: 2868} {Pfam: C-terminal domain of Sin3a protein [PF16879.7, score=98.6]} {Human: ENSG00000127511, SIN3B, SIN3 transcription regulator family member B, [Score=144, Expect=2e-35]; ENSG00000169375, SIN3A, SIN3 transcription regulator family member A, [Score=137, Expect=5e-33]} {Mouse: ENSMUSG00000031622, Sin3b, transcriptional regulator, SIN3B (yeast), [Score=160, Expect=2e-40]} {Dmel: FBgn0022764, Sin3A, [Score=108, Expect=4e-24]} {Smed: dd_Smed_v6_7034_0_1, dd_Smed_v6_7034_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_4899} {RNA1310_3136.1} {RNA815_1997} Mlig455_024855 {REF} {Length: 6647} {Pfam: C-terminal domain of Sin3a protein [PF16879.7, score=79.7]; Bacterial protein of unknown function (DUF937) [PF06078.13, score=19.1]} {Human: ENSG00000169375, SIN3A, SIN3 transcription regulator family member A, [Score=110, Expect=3e-25]; ENSG00000127511, SIN3B, SIN3 transcription regulator family member B, [Score=107, Expect=4e-24]} {Mouse: ENSMUSG00000031622, Sin3b, transcriptional regulator, SIN3B (yeast), [Score=141, Expect=1e-35]} {Dmel: FBgn0022764, Sin3A, [Score=107, Expect=2e-24]} {Smed: dd_Smed_v6_7034_0_1, dd_Smed_v6_7034_0_1, [Score=67.8, Expect=6e-12]} {RNA1509_56147} {RNA1310_3136.1} {RNA815_14715} |
9. | MligTC455_45072 | 2260 | 47.07 | Mlig455_050675, Mlig455_069624 | Neo: Int S/G2/M Age: logFC(26M/2M)=0.149 Regeneration-upregulated BL: 1.167 Regeneration-enriched BL: 1.167 |
VARS | 0.952 | - | - | - | 0.952 | - | - | Mlig455_050675 {REF} {Length: 4260} {TRANSSPLICED} {Pfam: tRNA synthetases class I (I, L, M and V) [PF00133.24, score=648.0]; Anticodon-binding domain of tRNA ligase [PF08264.15, score=127.0]; tRNA synthetases class I (M) [PF09334.13, score=45.9]; Leucyl-tRNA synthetase, Domain 2 [PF13603.8, score=32.8]; Valyl tRNA synthetase tRNA binding arm [PF10458.11, score=25.6]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=21.8]; Glutathione S-transferase, C-terminal domain [PF13410.8, score=21.3]; Glutathione S-transferase, C-terminal domain [PF14497.8, score=19.0]} {Human: ENSG00000231945, VARS, valyl-tRNA synthetase, [RH, Score=1100, Expect=0.0]; ENSG00000231116, VARS, valyl-tRNA synthetase, [RH, Score=1099, Expect=0.0]; ENSG00000096171, VARS, valyl-tRNA synthetase, [RH, Score=1099, Expect=0.0]; ENSG00000224264, VARS, valyl-tRNA synthetase, [RH, Score=1099, Expect=0.0]; ENSG00000226589, VARS, valyl-tRNA synthetase, [RH, Score=1099, Expect=0.0]; ENSG00000204394, VARS, valyl-tRNA synthetase, [RH, Score=1099, Expect=0.0]} {Mouse: ENSMUSG00000007029, Vars, valyl-tRNA synthetase, [RH, Score=1098, Expect=0.0]} {Dmel: FBgn0027079, ValRS, Valyl-tRNA synthetase, [RH, Score=1114, Expect=0.0]} {Celegans: WBGene00006936, glp-4, Valine--tRNA ligase, [RH, Score=1061, Expect=0.0]} {Smed: dd_Smed_v6_6873_0_1, dd_Smed_v6_6873_0_1, [RH, Score=992, Expect=0.0]} {RNA1509_2097} {RNA1310_2033, RNA1509_2097} {RNA1509_2097, RNA815_577} Mlig455_069624 {REF} {Length: 4147} {TRANSSPLICED} {Pfam: tRNA synthetases class I (I, L, M and V) [PF00133.24, score=633.6]; Anticodon-binding domain of tRNA ligase [PF08264.15, score=127.0]; tRNA synthetases class I (M) [PF09334.13, score=46.1]; Leucyl-tRNA synthetase, Domain 2 [PF13603.8, score=32.8]; Valyl tRNA synthetase tRNA binding arm [PF10458.11, score=25.7]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=21.9]; Glutathione S-transferase, C-terminal domain [PF13410.8, score=21.4]; Glutathione S-transferase, C-terminal domain [PF14497.8, score=19.0]} {Human: ENSG00000231945, VARS, valyl-tRNA synthetase, [Score=1042, Expect=0.0]; ENSG00000096171, VARS, valyl-tRNA synthetase, [Score=1041, Expect=0.0]; ENSG00000231116, VARS, valyl-tRNA synthetase, [Score=1041, Expect=0.0]; ENSG00000224264, VARS, valyl-tRNA synthetase, [Score=1041, Expect=0.0]; ENSG00000226589, VARS, valyl-tRNA synthetase, [Score=1041, Expect=0.0]; ENSG00000204394, VARS, valyl-tRNA synthetase, [Score=1041, Expect=0.0]} {Mouse: ENSMUSG00000007029, Vars, valyl-tRNA synthetase, [Score=1046, Expect=0.0]} {Dmel: FBgn0027079, ValRS, Valyl-tRNA synthetase, [RH, Score=1053, Expect=0.0]} {Celegans: WBGene00006936, glp-4, Valine--tRNA ligase, [RH, Score=1012, Expect=0.0]} {Smed: dd_Smed_v6_6873_0_1, dd_Smed_v6_6873_0_1, [RH, Score=958, Expect=0.0]} {RNA1509_2097} {RNA1310_2033} {RNA815_577} |
10. | MligTC455_16025 | 376 | 7.83 | Mlig455_000880 | Neo: - Age: - Region-enriched R5: 1.244/0.00707 |
IDE | 0.95 | - | - | - | 0.950 | - | - | Mlig455_000880 {REF} {Length: 3596} {Pfam: Peptidase M16 inactive domain [PF05193.23, score=37.0]; Middle or third domain of peptidase_M16 [PF16187.7, score=33.1]} {Human: ENSG00000119912, IDE, insulin degrading enzyme, [Score=182, Expect=2e-52]} {Mouse: ENSMUSG00000056999, Ide, insulin degrading enzyme, [Score=181, Expect=4e-50]; ENSMUSG00000111624, Ide, insulin degrading enzyme, [Score=181, Expect=4e-50]} {Dmel: FBgn0001247, Ide, Insulin degrading metalloproteinase, [Score=199, Expect=9e-57]} {Celegans: WBGene00018426, F44E7.4, [Score=147, Expect=1e-38]} {Smed: dd_Smed_v6_9500_1_1, dd_Smed_v6_9500_1_1, [Score=167, Expect=8e-46]} {RNA1509_34800, RNA1509_38131} {RNA1310_856.2, RNA1509_34800, RNA1509_38131} {RNA1509_34800, RNA1509_38131, RNA815_1063} |
11. | MligTC455_22380 | 1009 | 21.03 | Mlig455_004274, Mlig455_004359 | Neo: Int S/G2/M Age: - |
CDK9 | 0.95 | - | - | - | 0.950 | - | - | Mlig455_004274 {REF} {Length: 3137} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=23.9} {Pfam: Protein kinase domain [PF00069.27, score=230.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=110.7]; Kinase-like [PF14531.8, score=21.7]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=21.0]; ABC1 atypical kinase-like domain [PF03109.18, score=20.6]} {Human: ENSG00000136807, CDK9, cyclin dependent kinase 9, [RH, Score=391, Expect=1e-133]} {Mouse: ENSMUSG00000009555, Cdk9, cyclin-dependent kinase 9 (CDC2-related kinase), [RH, Score=390, Expect=2e-133]} {Dmel: FBgn0019949, Cdk9, Cyclin-dependent kinase 9, [RH, Score=390, Expect=6e-133]} {Celegans: WBGene00000410, cdk-9, Probable cyclin-dependent kinase 9, [RH, Score=321, Expect=3e-105]} {Smed: dd_Smed_v6_8520_0_1, dd_Smed_v6_8520_0_1, [RH, Score=333, Expect=4e-111]} {RNA1509_13492} {RNA1310_7809.1} {RNA815_9626} Mlig455_004359 {REF} {Length: 2701} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=230.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=110.7]; Kinase-like [PF14531.8, score=21.7]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=21.0]; ABC1 atypical kinase-like domain [PF03109.18, score=20.6]} {Human: ENSG00000136807, CDK9, cyclin dependent kinase 9, [RH, Score=391, Expect=1e-133]} {Mouse: ENSMUSG00000009555, Cdk9, cyclin-dependent kinase 9 (CDC2-related kinase), [RH, Score=390, Expect=2e-133]} {Dmel: FBgn0019949, Cdk9, Cyclin-dependent kinase 9, [RH, Score=390, Expect=5e-133]} {Celegans: WBGene00000410, cdk-9, Probable cyclin-dependent kinase 9, [RH, Score=321, Expect=3e-105]} {Smed: dd_Smed_v6_8520_0_1, dd_Smed_v6_8520_0_1, [RH, Score=333, Expect=3e-111]} {RNA1509_13492} {RNA1310_7809.1, RNA1509_13492} {RNA1509_13492, RNA815_9626} |