Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_17381 | 615 | 12.81 | Mlig455_039368 | Neo: Irradiation Age: logFC(26M/2M)=0.310 Region-enriched R5: 1.014/0.01425 |
ARID2 | Mlig455_039368 {REF} {Length: 4626} {Pfam: ARID/BRIGHT DNA binding domain [PF01388.23, score=67.4]} {Human: ENSG00000189079, ARID2, AT-rich interaction domain 2, [RH, Score=232, Expect=1e-61]} {Mouse: ENSMUSG00000033237, Arid2, AT rich interactive domain 2 (ARID, RFX-like), [RH, Score=234, Expect=3e-62]} {Dmel: FBgn0042085, Bap170, Brahma associated protein 170kD, [RH, Score=140, Expect=2e-33]} {Celegans: WBGene00007433, swsn-7, SWI/SNF nucleosome remodeling complex component, [RH, Score=166, Expect=2e-41]} {Smed: dd_Smed_v6_9463_0_1, dd_Smed_v6_9463_0_1, [RH, Score=246, Expect=8e-67]} {RNA1509_16299, RNA1509_8714} {RNA1310_10572.1, RNA1509_16299} {RNA1509_16299, RNA815_7460.2} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.469 | 3.981 | 0.70280 | 1.00000 | |
RegionR2 | -0.414 | 3.981 | 0.39173 | 0.78638 | |
RegionR3 | -0.642 | 3.981 | 0.12739 | 0.61395 | |
RegionR4 | 0.981 | 3.981 | 0.02101 | 0.10568 | |
RegionR5 | 1.014 | 3.981 | 0.00153 | 0.01425 | |
RegionR6 | 0.449 | 3.981 | 0.23615 | 0.81962 | |
RegionR7 | 0.658 | 3.981 | 0.16727 | 0.75308 | |
RegionR8 | -1.575 | 3.981 | 0.05476 | 0.45694 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 0.33 | 3.981 | 0.84454 | 1.00000 | |
RegenerationR2 | 0.719 | 3.981 | 0.04758 | 0.36004 | |
RegenerationR3 | 0.793 | 3.981 | 0.06333 | 0.42415 | |
RegenerationR4 | -0.258 | 3.981 | 0.51964 | 0.87894 | |
RegenerationR5 | 0.071 | 3.981 | 0.83345 | 0.99858 | |
RegenerationR6 | 0.594 | 3.981 | 0.12844 | 0.44039 | |
RegenerationBL | 1.202 | 3.981 | 0.01554 | 0.13146 | |
RegenerationTP | 0.627 | 3.981 | 0.32102 | 0.76579 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_17381 | 615 | 12.81 | Mlig455_039368 | Neo: Irradiation Age: logFC(26M/2M)=0.310 Region-enriched R5: 1.014/0.01425 |
ARID2 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_039368 {REF} {Length: 4626} {Pfam: ARID/BRIGHT DNA binding domain [PF01388.23, score=67.4]} {Human: ENSG00000189079, ARID2, AT-rich interaction domain 2, [RH, Score=232, Expect=1e-61]} {Mouse: ENSMUSG00000033237, Arid2, AT rich interactive domain 2 (ARID, RFX-like), [RH, Score=234, Expect=3e-62]} {Dmel: FBgn0042085, Bap170, Brahma associated protein 170kD, [RH, Score=140, Expect=2e-33]} {Celegans: WBGene00007433, swsn-7, SWI/SNF nucleosome remodeling complex component, [RH, Score=166, Expect=2e-41]} {Smed: dd_Smed_v6_9463_0_1, dd_Smed_v6_9463_0_1, [RH, Score=246, Expect=8e-67]} {RNA1509_16299, RNA1509_8714} {RNA1310_10572.1, RNA1509_16299} {RNA1509_16299, RNA815_7460.2} |
2. | MligTC455_17380 | 546 | 11.38 | Mlig455_013927 | Neo: Int S/G2/M Age: - Region-enriched R4: 1.295/0.04544 |
5.75 | 0.979 | 0.980 | 0.914 | 0.951 | 0.977 | 0.949 | Mlig455_013927 {REF} {Length: 509} {NoTransDecoderORF} {RNA1509_16299} {RNA1310_25375} {RNA815_11880} | |
3. | MligTC455_50021 | 605 | 12.6 | Mlig455_064511 | Neo: Neoblast Age: Down-Down-Up Region-enriched R4: 1.512/0.02076 |
NSD2 | 3.256 | 0.776 | 0.760 | - | 0.758 | - | 0.962 | Mlig455_064511 {REF} {Length: 4783} {TRANSSPLICED} {Pfam: PWWP domain [PF00855.19, score=113.6]; SET domain [PF00856.30, score=80.1]; AWS domain [PF17907.3, score=47.6]; PHD-finger [PF00628.31, score=38.8]; NSD Cys-His rich domain [PF17982.3, score=32.8]} {Human: ENSG00000109685, NSD2, nuclear receptor binding SET domain protein 2, [RH, Score=691, Expect=0.0]; ENSG00000165671, NSD1, nuclear receptor binding SET domain protein 1, [RH, Score=667, Expect=0.0]; ENSG00000147548, NSD3, nuclear receptor binding SET domain protein 3, [RH, Score=664, Expect=0.0]} {Mouse: ENSMUSG00000057406, Nsd2, nuclear receptor binding SET domain protein 2, [RH, Score=696, Expect=0.0]; ENSMUSG00000021488, Nsd1, nuclear receptor-binding SET-domain protein 1, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0039559, NSD, Nuclear receptor binding SET domain protein, [RH, Score=431, Expect=1e-130]} {Celegans: WBGene00016603, met-1, Histone-lysine N-methyltransferase, [Score=142, Expect=5e-34]} {Smed: dd_Smed_v6_4755_0_1, dd_Smed_v6_4755_0_1, [RH, Score=582, Expect=0.0]} {RNA1509_8385} {RNA1310_4002} {RNA815_849} |
4. | MligTC455_50020 | 590 | 12.29 | Mlig455_050575 | Neo: - Age: Down-Down-Down, logFC(26M/2M)=-4.649 Region-enriched R4: 1.440/0.03021 |
NSD2 | 3.243 | 0.766 | 0.754 | - | 0.760 | - | 0.963 | Mlig455_050575 {REF} {Length: 4368} {TRANSSPLICED} {Pfam: AWS domain [PF17907.3, score=47.8]; SET domain [PF00856.30, score=36.1]; PHD-finger [PF00628.31, score=36.0]; NSD Cys-His rich domain [PF17982.3, score=33.7]; PWWP domain [PF00855.19, score=29.5]} {Human: ENSG00000109685, NSD2, nuclear receptor binding SET domain protein 2, [Score=427, Expect=1e-130]; ENSG00000147548, NSD3, nuclear receptor binding SET domain protein 3, [Score=412, Expect=2e-124]} {Mouse: ENSMUSG00000057406, Nsd2, nuclear receptor binding SET domain protein 2, [Score=430, Expect=1e-131]; ENSMUSG00000021488, Nsd1, nuclear receptor-binding SET-domain protein 1, [Score=411, Expect=3e-122]} {Dmel: FBgn0039559, NSD, Nuclear receptor binding SET domain protein, [Score=246, Expect=2e-67]} {Celegans: WBGene00016603, met-1, Histone-lysine N-methyltransferase, [Score=79.0, Expect=1e-14]} {Smed: dd_Smed_v6_4755_0_2, dd_Smed_v6_4755_0_2, [Score=290, Expect=8e-86]} {RNA1509_8385} {RNA1310_4002} {RNA815_849} |
5. | MligTC455_29794 | 13232 | 275.67 | Mlig455_008533, Mlig455_023375, Mlig455_068951 | Neo: Neoblast, stringent Age: Down-Up-Up, logFC(26M/2M)=0.338 Regeneration-upregulated BL: 1.258 Regeneration-enriched BL: 1.258 |
DDX39B | 2.53 | - | 0.706 | - | 0.958 | - | 0.866 | Mlig455_008533 {REF} {Length: 1439} Mlig455_023375 {REF} {Length: 1739} {TRANSSPLICED} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=141.2]; Helicase conserved C-terminal domain [PF00271.33, score=92.8]; U3-containing 90S pre-ribosomal complex subunit [PF14617.8, score=33.4]; Type III restriction enzyme, res subunit [PF04851.17, score=29.8]} {Human: ENSG00000198563, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000229496, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000235439, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000225859, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000230624, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000215425, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000225073, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000123136, DDX39A, DExD-box helicase 39A, [RH, Score=701, Expect=0.0]} {Mouse: ENSMUSG00000019432, Ddx39b, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B, [RH, Score=716, Expect=0.0]; ENSMUSG00000005481, Ddx39, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39, [RH, Score=703, Expect=0.0]} {Dmel: FBgn0014189, Hel25E, Helicase at 25E, [RH, Score=699, Expect=0.0]} {Celegans: WBGene00001840, hel-1, Spliceosome RNA helicase DDX39B homolog, [RH, Score=655, Expect=0.0]} {Smed: dd_Smed_v6_724_0_1, dd_Smed_v6_724_0_1, [RH, Score=714, Expect=0.0]} {RNA1509_16673} {RNA1310_11845, RNA1509_16673} {RNA1509_16673, RNA815_6753} Mlig455_068951 {REF} {Length: 1734} {TRANSSPLICED} {Pfam: DEAD/DEAH box helicase [PF00270.31, score=141.2]; Helicase conserved C-terminal domain [PF00271.33, score=92.8]; U3-containing 90S pre-ribosomal complex subunit [PF14617.8, score=33.4]; Type III restriction enzyme, res subunit [PF04851.17, score=29.8]} {Human: ENSG00000225859, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000235439, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000215425, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000225073, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000198563, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000229496, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000230624, DDX39B, DExD-box helicase 39B, [RH, Score=717, Expect=0.0]; ENSG00000123136, DDX39A, DExD-box helicase 39A, [RH, Score=699, Expect=0.0]} {Mouse: ENSMUSG00000019432, Ddx39b, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B, [RH, Score=716, Expect=0.0]; ENSMUSG00000005481, Ddx39, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39, [RH, Score=703, Expect=0.0]} {Dmel: FBgn0014189, Hel25E, Helicase at 25E, [RH, Score=699, Expect=0.0]} {Celegans: WBGene00001840, hel-1, Spliceosome RNA helicase DDX39B homolog, [RH, Score=654, Expect=0.0]} {Smed: dd_Smed_v6_724_0_1, dd_Smed_v6_724_0_1, [RH, Score=713, Expect=0.0]} {RNA1509_16673} {RNA1310_11845} {RNA815_6753} |
6. | MligTC455_20586 | 596 | 12.41 | Mlig455_016355 | Neo: Int S/G2/M Age: - |
GPS1 | 1.765 | - | - | - | 0.799 | - | 0.966 | Mlig455_016355 {REF} {Length: 2810} {TRANSSPLICED} {Pfam: 26S proteasome subunit RPN7 [PF10602.11, score=151.8]; PCI domain [PF01399.29, score=57.5]} {Human: ENSG00000169727, GPS1, G protein pathway suppressor 1, [RH, Score=400, Expect=6e-135]} {Mouse: ENSMUSG00000025156, Gps1, G protein pathway suppressor 1, [RH, Score=404, Expect=2e-136]} {Dmel: FBgn0027057, CSN1b, COP9 signalosome subunit 1b, [RH, Score=366, Expect=1e-121]} {Celegans: WBGene00000813, csn-1, COP9 signalosome complex subunit 1, [RH, Score=179, Expect=1e-49]} {Smed: dd_Smed_v6_2705_0_1, dd_Smed_v6_2705_0_1, [RH, Score=305, Expect=5e-98]} {RNA1509_36879, RNA1509_8713} {RNA1310_17431.1, RNA1509_36879, RNA1509_8713} {RNA1509_36879, RNA1509_8713, RNA815_5660} |
7. | MligTC455_12932 | 233 | 4.86 | Mlig455_068053 | Neo: - Age: Down-Down-Up Region-enriched R2: 2.157/0.04323 |
ANKRD40 | 1.736 | 0.785 | - | - | - | - | 0.951 | Mlig455_068053 {REF} {Length: 4350} {Pfam: OCRE domain [PF17780.3, score=45.6]; Ankyrin repeats (many copies) [PF13637.8, score=34.0]; Ankyrin repeat [PF00023.32, score=31.1]; Ankyrin repeats (3 copies) [PF12796.9, score=30.9]; Ankyrin repeats (many copies) [PF13857.8, score=25.7]; Ankyrin repeat [PF13606.8, score=19.8]} {Human: ENSG00000154945, ANKRD40, ankyrin repeat domain 40, [RH, Score=94.0, Expect=6e-20]} {Mouse: ENSMUSG00000020864, Ankrd40, ankyrin repeat domain 40, [RH, Score=93.2, Expect=7e-20]} {Dmel: FBgn0031319, CG4896, [Score=57.4, Expect=4e-08]} {Celegans: WBGene00011270, R31.2, [RH, Score=83.6, Expect=1e-16]} {Smed: dd_Smed_v6_2392_0_2, dd_Smed_v6_2392_0_2, [Score=58.2, Expect=1e-08]} {RNA1509_49616, RNA1509_49906} {RNA1310_18118, RNA1509_49906} {RNA1509_49906, RNA815_7502} |
8. | MligTC455_15857 | 1438 | 29.96 | Mlig455_021333 | Neo: - Age: - |
HMGCS1 | 1.711 | - | - | - | 0.740 | - | 0.971 | Mlig455_021333 {REF} {Length: 2055} {TRANSSPLICED} {Pfam: Hydroxymethylglutaryl-coenzyme A synthase C terminal [PF08540.12, score=270.1]; Hydroxymethylglutaryl-coenzyme A synthase N terminal [PF01154.19, score=268.9]} {Human: ENSG00000112972, HMGCS1, 3-hydroxy-3-methylglutaryl-CoA synthase 1, [RH, Score=418, Expect=2e-142]; ENSG00000134240, HMGCS2, 3-hydroxy-3-methylglutaryl-CoA synthase 2, [RH, Score=410, Expect=3e-139]} {Mouse: ENSMUSG00000027875, Hmgcs2, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2, [RH, Score=425, Expect=3e-145]; ENSMUSG00000093930, Hmgcs1, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1, [RH, Score=416, Expect=1e-141]} {Dmel: FBgn0010611, Hmgs, HMG Coenzyme A synthase, [RH, Score=452, Expect=1e-156]} {Celegans: WBGene00017769, hmgs-1, Hydroxymethylglutaryl-CoA synthase, [RH, Score=347, Expect=2e-115]} {Smed: dd_Smed_v6_2847_0_1, dd_Smed_v6_2847_0_1, [RH, Score=378, Expect=2e-128]} {RNA1509_56340, RNA1509_9086} {RNA1310_11344.1, RNA1509_56340, RNA1509_9086} {RNA1509_56340, RNA1509_9086, RNA815_4806} |
9. | MligTC455_05897 | 665 | 13.85 | Mlig455_049059 | Neo: - Age: - |
LNX2 | 0.961 | - | - | - | - | - | 0.961 | Mlig455_049059 {REF} {Length: 6005} {TRANSSPLICED} {Pfam: PDZ domain [PF00595.26, score=182.6]; PDZ domain [PF17820.3, score=100.7]; PDZ domain [PF13180.8, score=57.3]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=27.9]; RING-type zinc-finger [PF13445.8, score=27.7]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=27.1]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=25.9]; TRAF-type zinc finger [PF02176.20, score=25.1]; zinc-RING finger domain [PF14634.8, score=22.9]; Ring finger domain [PF13639.8, score=22.5]; zinc finger of C3HC4-type, RING [PF15227.8, score=19.1]} {Human: ENSG00000139517, LNX2, ligand of numb-protein X 2, [Score=427, Expect=2e-138]} {Mouse: ENSMUSG00000016520, Lnx2, ligand of numb-protein X 2, [Score=416, Expect=3e-134]} {Dmel: FBgn0000008, a, arc, [RH, Score=70.9, Expect=4e-12]} {Celegans: WBGene00003404, mpz-1, Multiple PDZ domain protein, [Score=155, Expect=3e-40]} {Smed: dd_Smed_v6_8994_0_2, dd_Smed_v6_8994_0_2, [RH, Score=527, Expect=2e-175]} {RNA1509_14988} {RNA1310_9030} {RNA815_6198} |
10. | MligTC455_45485 | 766 | 15.96 | Mlig455_004917 | Neo: - Age: - |
DLG2 | 0.958 | - | - | - | - | - | 0.958 | Mlig455_004917 {REF} {Length: 3289} {Pfam: Guanylate kinase [PF00625.23, score=164.7]; PDZ domain [PF00595.26, score=69.8]; PDZ domain [PF17820.3, score=37.6]; SH3 domain [PF00018.30, score=33.0]; Variant SH3 domain [PF07653.19, score=27.3]; PDZ domain [PF13180.8, score=22.1]; Variant SH3 domain [PF14604.8, score=20.5]} {Human: ENSG00000150672, DLG2, discs large MAGUK scaffold protein 2, [RH, Score=436, Expect=1e-141]; ENSG00000075711, DLG1, discs large MAGUK scaffold protein 1, [RH, Score=418, Expect=7e-137]} {Mouse: ENSMUSG00000052572, Dlg2, discs large MAGUK scaffold protein 2, [RH, Score=435, Expect=9e-143]; ENSMUSG00000022770, Dlg1, discs large MAGUK scaffold protein 1, [RH, Score=414, Expect=3e-135]} {Dmel: FBgn0001624, dlg1, discs large 1, [Score=446, Expect=2e-146]} {Celegans: WBGene00001006, dlg-1, Drosophila Discs LarGe homolog; MAGUK protein DLG-1; SAP97-like protein DLG-1, [RH, Score=357, Expect=5e-112]} {Smed: dd_Smed_v6_8511_0_1, dd_Smed_v6_8511_0_1, [RH, Score=322, Expect=4e-103]} {RNA1509_19643, RNA1509_26114, RNA1509_42144} {RNA1310_2555.1, RNA1509_19643, RNA1509_26114, RNA1509_42144} {RNA1509_19643, RNA1509_26114, RNA1509_42144, RNA815_2319} |
11. | MligTC455_21289 | 431 | 8.99 | Mlig455_065603 | Neo: - Age: Up-Down-Down |
CCNYL1 | 0.957 | - | - | - | - | - | 0.957 | Mlig455_065603 {REF} {Length: 2997} {Pfam: Cyclin, N-terminal domain [PF00134.25, score=36.6]; Cyclin [PF08613.13, score=30.4]} {Human: ENSG00000163249, CCNYL1, cyclin Y like 1, [RH, Score=197, Expect=2e-64]} {Mouse: ENSMUSG00000024286, Ccny, cyclin Y, [Score=204, Expect=1e-64]; ENSMUSG00000070871, Ccnyl1, cyclin Y-like 1, [Score=198, Expect=5e-63]} {Dmel: FBgn0032378, CycY, Cyclin Y, [Score=199, Expect=4e-62]} {Celegans: WBGene00022697, cyy-1, Cyclin-Y, [Score=191, Expect=1e-59]} {Smed: dd_Smed_v6_8226_0_1, dd_Smed_v6_8226_0_1, [Score=177, Expect=5e-54]} {RNA1509_8018} {RNA1310_8716} {RNA815_15699} |
12. | MligTC455_37766 | 513 | 10.69 | Mlig455_029955 | Neo: - Age: - Region-enriched R2: 3.095/0.00006 |
IVNS1ABP | 0.956 | - | - | - | - | - | 0.956 | Mlig455_029955 {REF} {Length: 3595} {TRANSSPLICED} {Pfam: Kelch motif [PF01344.27, score=108.7]; BTB/POZ domain [PF00651.33, score=57.5]; Kelch motif [PF13964.8, score=40.3]; Galactose oxidase, central domain [PF13418.8, score=29.5]; Kelch motif [PF13854.8, score=19.4]} {Human: ENSG00000116679, IVNS1ABP, influenza virus NS1A binding protein, [Score=124, Expect=8e-29]} {Mouse: ENSMUSG00000023150, Ivns1abp, influenza virus NS1A binding protein, [Score=119, Expect=2e-27]} {Dmel: FBgn0040230, dbo, diablo, [Score=92.4, Expect=4e-19]} {Celegans: WBGene00006493, tag-147, [Score=125, Expect=2e-29]} {Smed: dd_Smed_v6_5109_0_1, dd_Smed_v6_5109_0_1, [Score=137, Expect=3e-33]} {RNA1509_41046, RNA1509_6617} {RNA1310_3820, RNA1509_41046, RNA1509_6617} {RNA1509_41046, RNA1509_6617, RNA815_4140} |
13. | MligTC455_19926 | 1427 | 29.74 | Mlig455_025233 | Neo: - Age: Up-Down-Up |
MRPS14 | 0.95 | - | - | - | 0.950 | - | - | Mlig455_025233 {REF} {Length: 1821} {TRANSSPLICED} {Pfam: Ribosomal protein S14p/S29e [PF00253.23, score=65.2]} {Human: ENSG00000120333, MRPS14, mitochondrial ribosomal protein S14, [RH, Score=89.7, Expect=9e-23]} {Mouse: ENSMUSG00000058267, Mrps14, mitochondrial ribosomal protein S14, [RH, Score=92.4, Expect=6e-24]} {Dmel: FBgn0044030, mRpS14, mitochondrial ribosomal protein S14, [RH, Score=79.0, Expect=7e-19]} {Celegans: WBGene00011334, mrps-14, Probable 40S ribosomal protein S14, mitochondrial, [Score=66.2, Expect=1e-13]} {Smed: dd_Smed_v6_4035_0_1, dd_Smed_v6_4035_0_1, [Score=127, Expect=1e-36]} {RNA1509_14947} {RNA1310_21105} {RNA815_11131.2} |