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Results for MligTC455_18507

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_18507 1488 30.99 Mlig455_034016

Neo: -

Age: logFC(26M/2M)=-0.250

 AK8 Mlig455_034016 {REF} {Length: 1723} {Pfam: Adenylate kinase [PF00406.24, score=158.5]; AAA domain [PF13207.8, score=82.9]; AAA domain [PF13238.8, score=31.9]; Hydin Adenylate kinase-like domain [PF17213.5, score=30.1]; AAA domain [PF13671.8, score=26.8]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=23.1]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=18.7]} {Human: ENSG00000165695, AK8, adenylate kinase 8, [RH, Score=422, Expect=2e-143]} {Mouse: ENSMUSG00000026807, Ak8, adenylate kinase 8, [RH, Score=413, Expect=3e-140]} {Dmel: FBgn0283494, Adk2, Adenylate kinase 2, [Score=106, Expect=7e-26]} {Celegans: WBGene00002879, let-754, Adenylate kinase, [Score=100, Expect=6e-24]} {Smed: dd_Smed_v6_7317_0_1, dd_Smed_v6_7317_0_1, [RH, Score=431, Expect=1e-147]} {RNA1509_18238} {RNA1310_18637.1, RNA1509_18238} {RNA1509_18238, RNA815_7186}

Cumulative graph for MligTC455_18507

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.202 5.15 0.77468 1.00000
RegionR2 0.351 5.15 0.29470 0.68324
RegionR3 0.177 5.15 0.53120 1.00000
RegionR4 0.324 5.15 0.31873 0.63498
RegionR5 -0.428 5.15 0.12977 0.36561
RegionR6 0.039 5.15 0.89418 1.00000
RegionR7 -0.627 5.15 0.12256 0.66080
RegionR8 -0.038 5.15 0.93708 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -2.882 5.15 0.02940 0.62391
RegenerationR2 0.268 5.15 0.35537 0.78558
RegenerationR3 0.246 5.15 0.43977 0.82700
RegenerationR4 0.089 5.15 0.78584 0.98254
RegenerationR5 -0.099 5.15 0.76114 0.97584
RegenerationR6 -0.092 5.15 0.78321 0.96912
RegenerationBL 0.006 5.15 0.98616 1.00000
RegenerationTP 0.078 5.15 0.85603 1.00000


Genes with expression patterns similar to MligTC455_18507

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_18507 1488 30.99 Mlig455_034016

Neo: -

Age: logFC(26M/2M)=-0.250

 AK8 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_034016 {REF} {Length: 1723} {Pfam: Adenylate kinase [PF00406.24, score=158.5]; AAA domain [PF13207.8, score=82.9]; AAA domain [PF13238.8, score=31.9]; Hydin Adenylate kinase-like domain [PF17213.5, score=30.1]; AAA domain [PF13671.8, score=26.8]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=23.1]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=18.7]} {Human: ENSG00000165695, AK8, adenylate kinase 8, [RH, Score=422, Expect=2e-143]} {Mouse: ENSMUSG00000026807, Ak8, adenylate kinase 8, [RH, Score=413, Expect=3e-140]} {Dmel: FBgn0283494, Adk2, Adenylate kinase 2, [Score=106, Expect=7e-26]} {Celegans: WBGene00002879, let-754, Adenylate kinase, [Score=100, Expect=6e-24]} {Smed: dd_Smed_v6_7317_0_1, dd_Smed_v6_7317_0_1, [RH, Score=431, Expect=1e-147]} {RNA1509_18238} {RNA1310_18637.1, RNA1509_18238} {RNA1509_18238, RNA815_7186}
2. MligTC455_42863 4143 86.31 Mlig455_015957

Neo: -

Age: -

 CCDC65 4.387 - 0.784 0.891 0.853 0.953 0.906 Mlig455_015957 {REF} {Length: 1928} {TRANSSPLICED} {Pfam: Sperm tail [PF14772.8, score=82.2]; Sperm tail C-terminal domain [PF14775.8, score=25.0]} {Human: ENSG00000139537, CCDC65, coiled-coil domain containing 65, [RH, Score=401, Expect=3e-135]} {Mouse: ENSMUSG00000003354, Ccdc65, coiled-coil domain containing 65, [RH, Score=420, Expect=1e-142]} {Dmel: FBgn0050259, CG30259, [RH, Score=166, Expect=8e-45]} {Smed: dd_Smed_v6_6152_0_1, dd_Smed_v6_6152_0_1, [RH, Score=525, Expect=0.0]} {RNA1509_10456, RNA1509_14724, RNA1509_1709, RNA1509_21982, RNA1509_37196} {RNA1310_14593, RNA1509_10456, RNA1509_14724, RNA1509_1709, RNA1509_21982, RNA1509_37196} {RNA1509_10456, RNA1509_14724, RNA1509_1709, RNA1509_21982, RNA1509_37196, RNA815_5330}
3. MligTC455_50677 3742 77.95 Mlig455_024461

Neo: -

Age: -

 IQCD 3.507 - 0.847 0.797 - 0.952 0.911 Mlig455_024461 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1310_4220.1, RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931, RNA815_1223.1}
4. MligTC455_50676 3764 78.41 Mlig455_024344

Neo: -

Age: -

 IQCD 3.499 - 0.835 0.802 - 0.951 0.911 Mlig455_024344 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_1833, RNA1509_46413} {RNA1310_4220.1, RNA1509_46413} {RNA1509_46413, RNA815_1223.1}
5. MligTC455_48147 4787 99.73 Mlig455_037839

Neo: -

Age: -

Region-enriched R2: 1.555/0.00031
Region-enriched R3: 1.156/0.00180

 DNAI2 3.496 - 0.789 0.863 - 0.965 0.879 Mlig455_037839 {REF} {Length: 2372} {Human: ENSG00000171595, DNAI2, dynein axonemal intermediate chain 2, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000034706, Dnaic2, dynein, axonemal, intermediate chain 2, [RH, Score=736, Expect=0.0]} {Dmel: FBgn0036195, Dnai2, dynein, axonemal, intermediate chain 2, [RH, Score=556, Expect=0.0]} {Smed: dd_Smed_v6_2644_0_1, dd_Smed_v6_2644_0_1, [RH, Score=865, Expect=0.0]} {RNA1509_667} {RNA1310_10436} {RNA815_3551}
6. MligTC455_44023 2719 56.64 Mlig455_004982, Mlig455_005292

Neo: -

Age: -

Region-enriched R2: 1.232/0.02120

 CFAP206 3.477 - - 0.770 0.832 0.950 0.925

Mlig455_004982 {REF} {Length: 2163} {TRANSSPLICED} {Pfam: Domain of unknown function [PF12018.10, score=313.9]} {Human: ENSG00000272514, CFAP206, cilia and flagella associated protein 206, [RH, Score=600, Expect=0.0]; ENSG00000213204, AL049697.1, novel transcript, C6orf165-SLC35A1 readthrough, [RH, Score=600, Expect=0.0]} {Mouse: ENSMUSG00000028294, Cfap206, cilia and flagella associated protein 206, [RH, Score=618, Expect=0.0]} {Dmel: FBgn0034532, CG13436, [RH, Score=85.9, Expect=2e-17]} {Smed: dd_Smed_v6_11199_0_1, dd_Smed_v6_11199_0_1, [RH, Score=683, Expect=0.0]} {RNA1509_3595} {RNA1310_11402, RNA1509_3595} {RNA1509_3595, RNA815_4138}

Mlig455_005292 {REF} {Length: 2167} {TRANSSPLICED} {Pfam: Domain of unknown function [PF12018.10, score=312.8]} {Human: ENSG00000272514, CFAP206, cilia and flagella associated protein 206, [RH, Score=599, Expect=0.0]; ENSG00000213204, AL049697.1, novel transcript, C6orf165-SLC35A1 readthrough, [RH, Score=599, Expect=0.0]} {Mouse: ENSMUSG00000028294, Cfap206, cilia and flagella associated protein 206, [RH, Score=617, Expect=0.0]} {Dmel: FBgn0034532, CG13436, [RH, Score=85.1, Expect=4e-17]} {Smed: dd_Smed_v6_11199_0_1, dd_Smed_v6_11199_0_1, [RH, Score=683, Expect=0.0]} {RNA1509_3595} {RNA1310_11402} {RNA815_4138}
7. MligTC455_36603 6393 133.19 Mlig455_056234

Neo: -

Age: Down-Up-Up

 ENKUR 3.474 - 0.830 0.831 - 0.858 0.955 Mlig455_056234 {REF} {Length: 3195} {Pfam: Calmodulin-binding [PF13864.8, score=104.0]} {Human: ENSG00000151023, ENKUR, enkurin, TRPC channel interacting protein, [RH, Score=254, Expect=6e-85]} {Mouse: ENSMUSG00000026679, Enkur, enkurin, TRPC channel interacting protein, [RH, Score=246, Expect=1e-81]} {Dmel: FBgn0062517, CG16984, [RH, Score=85.9, Expect=2e-19]} {Smed: dd_Smed_v6_2868_0_1, dd_Smed_v6_2868_0_1, [RH, Score=287, Expect=2e-98]} {RNA1509_2514} {RNA1310_24045.1} {RNA815_10197}
8. MligTC455_36602 6389 133.11 Mlig455_041345

Neo: -

Age: logFC(26M/2M)=-0.295

 ENKUR 3.47 - 0.829 0.826 - 0.861 0.954 Mlig455_041345 {REF} {Length: 2476} {Pfam: Calmodulin-binding [PF13864.8, score=104.1]} {Human: ENSG00000151023, ENKUR, enkurin, TRPC channel interacting protein, [RH, Score=258, Expect=4e-86]} {Mouse: ENSMUSG00000026679, Enkur, enkurin, TRPC channel interacting protein, [RH, Score=248, Expect=1e-82]} {Dmel: FBgn0062517, CG16984, [RH, Score=87.0, Expect=8e-20]} {Smed: dd_Smed_v6_2868_0_1, dd_Smed_v6_2868_0_1, [RH, Score=290, Expect=4e-99]} {RNA1509_10822, RNA1509_23660, RNA1509_2514, RNA1509_31109, RNA1509_32898, RNA1509_37290, RNA1509_58953} {RNA1310_24045.1, RNA1509_10822, RNA1509_23660, RNA1509_2514, RNA1509_31109, RNA1509_32898, RNA1509_37290, RNA1509_58953} {RNA1509_10822, RNA1509_23660, RNA1509_2514, RNA1509_31109, RNA1509_32898, RNA1509_37290, RNA1509_58953, RNA815_10197}
9. MligTC455_37360 5178 107.87 Mlig455_043000

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.956

 CFAP52 3.365 - 0.760 0.766 - 0.950 0.889 Mlig455_043000 {REF} {Length: 2520} {Pfam: WD domain, G-beta repeat [PF00400.34, score=124.0]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=41.8]; WD40-like domain [PF17005.7, score=26.5]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=748, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=756, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=439, Expect=3e-145]} {Celegans: WBGene00022119, copa-1, Coatomer subunit alpha, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=838, Expect=0.0]} {RNA1509_1341} {RNA1310_8859} {RNA815_2855}
10. MligTC455_40089 1886 39.29 Mlig455_065378

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.262

 C9orf135 3.356 - 0.721 - 0.878 0.803 0.954 Mlig455_065378 {REF} {Length: 1881} {Pfam: Domain of unknown function (DUF4572) [PF15139.8, score=148.3]} {Human: ENSG00000204711, C9orf135, chromosome 9 open reading frame 135, [RH, Score=106, Expect=8e-26]} {Mouse: ENSMUSG00000033053, 1700028P14Rik, RIKEN cDNA 1700028P14 gene, [RH, Score=85.9, Expect=9e-19]} {Smed: dd_Smed_v6_8797_0_1, dd_Smed_v6_8797_0_1, [RH, Score=123, Expect=7e-33]} {RNA1509_3475, RNA1509_34777} {RNA1310_27695.1, RNA1509_3475, RNA1509_34777} {RNA1509_3475, RNA1509_34777, RNA815_12226}
11. MligTC455_50431 370 7.7 Mlig455_012674

Neo: -

Age: -

 ANKRD33 3.155 - 0.722 0.753 0.730 0.950 - Mlig455_012674 {REF} {Length: 2137} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=57.9]; Ankyrin repeats (many copies) [PF13637.8, score=56.3]; Ankyrin repeats (many copies) [PF13857.8, score=49.8]; Ankyrin repeat [PF00023.32, score=34.1]; Ankyrin repeat [PF13606.8, score=26.4]} {Human: ENSG00000167612, ANKRD33, ankyrin repeat domain 33, [RH, Score=58.5, Expect=2e-08]} {Mouse: ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=59.7, Expect=3e-09]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=59.3, Expect=4e-09]; ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=59.3, Expect=4e-09]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=58.5, Expect=7e-09]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=58.5, Expect=7e-09]; ENSMUSG00000022237, Ankrd33b, ankyrin repeat domain 33B, [Score=57.0, Expect=3e-08]} {Dmel: FBgn0029137, Patsas, [Score=56.6, Expect=4e-08]} {Celegans: WBGene00006490, kdin-1, KiDINs220 (Vertebrate scaffold protein) homolog, [Score=54.3, Expect=2e-07]} {Smed: dd_Smed_v6_13721_0_1, dd_Smed_v6_13721_0_1, [Score=57.8, Expect=2e-08]} {RNA1509_8000} {RNA1310_3084.1} {RNA815_6850}
12. MligTC455_49237 1147 23.89 Mlig455_053089

Neo: -

Age: Down-Up-Down

 CAMK4 2.642 - - - 0.829 0.973 0.840 Mlig455_053089 {REF} {Length: 2761} {Pfam: Protein kinase domain [PF00069.27, score=263.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=117.6]; Fungal protein kinase [PF17667.3, score=24.4]; ABC1 atypical kinase-like domain [PF03109.18, score=20.0]} {Human: ENSG00000152495, CAMK4, calcium/calmodulin dependent protein kinase IV, [Score=351, Expect=4e-118]} {Mouse: ENSMUSG00000038128, Camk4, calcium/calmodulin-dependent protein kinase IV, [Score=353, Expect=3e-119]} {Dmel: FBgn0016126, CaMKI, Calcium/calmodulin-dependent protein kinase I, [Score=248, Expect=2e-79]} {Celegans: WBGene00000553, cmk-1, Calcium/calmodulin-dependent protein kinase type 1, [Score=245, Expect=8e-79]} {Smed: dd_Smed_v6_10731_0_1, dd_Smed_v6_10731_0_1, [Score=357, Expect=1e-122]} {RNA1509_27017, RNA1509_8403} {RNA1310_11195.2, RNA1509_27017, RNA1509_8403} {RNA1509_27017, RNA1509_8403, RNA815_9103.1}
13. MligTC455_49052 6202 129.21 Mlig455_020083, Mlig455_040897

Neo: -

Age: logFC(26M/2M)=-0.503

Region-enriched R2: 1.159/0.03703

 PACRG 2.584 - 0.812 - 0.821 0.951 -

Mlig455_020083 {REF} {Length: 1698} {Pfam: Parkin co-regulated protein [PF10274.11, score=275.9]} {Human: ENSG00000112530, PACRG, parkin coregulated, [RH, Score=352, Expect=8e-124]} {Mouse: ENSMUSG00000037196, Pacrg, PARK2 co-regulated, [RH, Score=350, Expect=3e-123]} {Dmel: FBgn0034454, CG15120, [RH, Score=268, Expect=4e-90]} {Celegans: WBGene00017122, pcrg-1, Parkin Co-Regulated Gene (PACRG) homolog, [RH, Score=102, Expect=4e-26]} {Smed: dd_Smed_v6_3899_0_1, dd_Smed_v6_3899_0_1, [RH, Score=384, Expect=4e-137]} {RNA1509_678} {RNA1310_20104.1} {RNA815_152.1}

Mlig455_040897 {REF} {Length: 1568} {TRANSSPLICED} {Pfam: Parkin co-regulated protein [PF10274.11, score=275.9]} {Human: ENSG00000112530, PACRG, parkin coregulated, [RH, Score=352, Expect=8e-124]} {Mouse: ENSMUSG00000037196, Pacrg, PARK2 co-regulated, [RH, Score=350, Expect=3e-123]} {Dmel: FBgn0034454, CG15120, [RH, Score=268, Expect=4e-90]} {Celegans: WBGene00017122, pcrg-1, Parkin Co-Regulated Gene (PACRG) homolog, [RH, Score=102, Expect=4e-26]} {Smed: dd_Smed_v6_3899_0_1, dd_Smed_v6_3899_0_1, [RH, Score=384, Expect=4e-137]} {RNA1509_678} {RNA1310_20104.1} {RNA815_152.1}
14. MligTC455_22235 6787 141.4 Mlig455_032864

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.356

 EFHC2 2.57 - 0.791 - - 0.826 0.953 Mlig455_032864 {REF} {Length: 3541} {Pfam: DUF1126 PH-like domain [PF06565.14, score=338.3]; EF hand [PF00036.34, score=18.1]} {Human: ENSG00000183690, EFHC2, EF-hand domain containing 2, [RH, Score=657, Expect=0.0]} {Mouse: ENSMUSG00000025038, Efhc2, EF-hand domain (C-terminal) containing 2, [RH, Score=663, Expect=0.0]} {Dmel: FBgn0034487, Efhc1.2, EF-hand domain containing 1.2, [RH, Score=417, Expect=7e-135]} {Celegans: WBGene00013028, efhc-1, EF-Hand domain-Containing protein 1 homolog, [Score=97.8, Expect=3e-21]} {Smed: dd_Smed_v6_6035_0_1, dd_Smed_v6_6035_0_1, [RH, Score=829, Expect=0.0]} {RNA1509_6224, RNA1509_965} {RNA1310_5674, RNA1509_965} {RNA1509_965, RNA815_1927.1}
15. MligTC455_24490 4954 103.2 Mlig455_053651

Neo: -

Age: -

 ATP2B2 2.532 - - - 0.729 0.963 0.840 Mlig455_053651 {REF} {Length: 4649} {TRANSSPLICED} {Pfam: Cation transporting ATPase, C-terminus [PF00689.23, score=150.9]; E1-E2 ATPase [PF00122.22, score=109.1]; Cation transport ATPase (P-type) [PF13246.8, score=67.7]; haloacid dehalogenase-like hydrolase [PF00702.28, score=59.0]; Cation transporter/ATPase, N-terminus [PF00690.28, score=56.4]; Plasma membrane calcium transporter ATPase C terminal [PF12424.10, score=55.3]; haloacid dehalogenase-like hydrolase [PF08282.14, score=26.4]} {Human: ENSG00000157087, ATP2B2, ATPase plasma membrane Ca2+ transporting 2, [RH, Score=1272, Expect=0.0]; ENSG00000067842, ATP2B3, ATPase plasma membrane Ca2+ transporting 3, [RH, Score=1266, Expect=0.0]; ENSG00000058668, ATP2B4, ATPase plasma membrane Ca2+ transporting 4, [RH, Score=1242, Expect=0.0]; ENSG00000070961, ATP2B1, ATPase plasma membrane Ca2+ transporting 1, [RH, Score=1220, Expect=0.0]} {Mouse: ENSMUSG00000031376, Atp2b3, ATPase, Ca++ transporting, plasma membrane 3, [RH, Score=1263, Expect=0.0]; ENSMUSG00000030302, Atp2b2, ATPase, Ca++ transporting, plasma membrane 2, [RH, Score=1262, Expect=0.0]; ENSMUSG00000019943, Atp2b1, ATPase, Ca++ transporting, plasma membrane 1, [RH, Score=1230, Expect=0.0]; ENSMUSG00000026463, Atp2b4, ATPase, Ca++ transporting, plasma membrane 4, [RH, Score=1204, Expect=0.0]} {Dmel: FBgn0259214, PMCA, plasma membrane calcium ATPase, [RH, Score=1311, Expect=0.0]} {Celegans: WBGene00003153, mca-3, Calcium-transporting ATPase, [RH, Score=1269, Expect=0.0]} {Smed: dd_Smed_v6_4145_0_1, dd_Smed_v6_4145_0_1, [RH, Score=1348, Expect=0.0]} {RNA1509_15679, RNA1509_19149, RNA1509_374, RNA1509_55618, RNA1509_59128} {RNA1310_4479.2, RNA1509_15679, RNA1509_19149, RNA1509_374, RNA1509_55618, RNA1509_59128} {RNA1509_15679, RNA1509_19149, RNA1509_374, RNA1509_55618, RNA1509_59128, RNA815_368.1}
16. MligTC455_41702 2176 45.34 Mlig455_055307

Neo: -

Age: Down-Up-Up

 CYP2C8 2.415 - - 0.722 - 0.970 0.723 Mlig455_055307 {REF} {Length: 2612} {Pfam: Cytochrome P450 [PF00067.24, score=306.8]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=259, Expect=6e-80]} {Mouse: ENSMUSG00000030483, Cyp2b10, cytochrome P450, family 2, subfamily b, polypeptide 10, [Score=257, Expect=2e-79]; ENSMUSG00000040660, Cyp2b9, cytochrome P450, family 2, subfamily b, polypeptide 9, [Score=249, Expect=2e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=247, Expect=2e-75]; ENSMUSG00000040650, Cyp2b23, cytochrome P450, family 2, subfamily b, polypeptide 23, [Score=246, Expect=3e-75]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=246, Expect=1e-74]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=246, Expect=1e-74]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=180, Expect=4e-50]} {Celegans: WBGene00018261, cyp-33C5, CYtochrome P450 family, [Score=221, Expect=7e-66]} {Smed: dd_Smed_v6_2351_0_1, dd_Smed_v6_2351_0_1, [RH, Score=279, Expect=4e-88]} {RNA1509_10256, RNA1509_15694, RNA1509_40717} {RNA1310_11391, RNA1509_10256, RNA1509_15694, RNA1509_40717} {RNA1509_10256, RNA1509_15694, RNA1509_40717, RNA815_585.2}
17. MligTC455_43338 3043 63.4 Mlig455_057398, Mlig455_059559

Neo: -

Age: logFC(26M/2M)=-0.259

Region-enriched R2: 1.086/0.00779

 CYB5D1 2.39 - - 0.715 0.712 0.963 -

Mlig455_057398 {REF} {Length: 1138} {Pfam: Ubiquitin-2 like Rad60 SUMO-like [PF11976.10, score=25.8]} {Human: ENSG00000182224, CYB5D1, cytochrome b5 domain containing 1, [Score=215, Expect=1e-70]} {Mouse: ENSMUSG00000044795, Cyb5d1, cytochrome b5 domain containing 1, [Score=223, Expect=7e-74]; ENSMUSG00000032889, Gm6685, predicted pseudogene 6685, [Score=221, Expect=3e-73]} {RNA1509_11346} {RNA1310_26198} {RNA815_11579}

Mlig455_059559 {REF} {Length: 1306} {Pfam: Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=35.0]; Ubiquitin-2 like Rad60 SUMO-like [PF11976.10, score=25.5]} {Human: ENSG00000182224, CYB5D1, cytochrome b5 domain containing 1, [RH, Score=260, Expect=6e-88]} {Mouse: ENSMUSG00000044795, Cyb5d1, cytochrome b5 domain containing 1, [RH, Score=263, Expect=2e-89]; ENSMUSG00000032889, Gm6685, predicted pseudogene 6685, [RH, Score=260, Expect=3e-88]} {RNA1509_5289} {RNA1310_26198, RNA1509_5289} {RNA1509_5289, RNA815_11579}
18. MligTC455_36972 3248 67.67 Mlig455_065599

Neo: -

Age: logFC(26M/2M)=-0.131

 KIF9 1.869 - - - - 0.912 0.957 Mlig455_065599 {REF} {Length: 4173} {TRANSSPLICED} {Pfam: Kinesin motor domain [PF00225.25, score=307.7]; Microtubule binding [PF16796.7, score=69.0]} {Human: ENSG00000088727, KIF9, kinesin family member 9, [RH, Score=605, Expect=0.0]} {Mouse: ENSMUSG00000032489, Kif9, kinesin family member 9, [RH, Score=640, Expect=0.0]} {Dmel: FBgn0004380, Klp64D, Kinesin-like protein at 64D, [Score=212, Expect=2e-58]} {Celegans: WBGene00003884, osm-3, Osmotic avoidance abnormal protein 3, [Score=222, Expect=4e-62]} {Smed: dd_Smed_v6_6755_0_1, dd_Smed_v6_6755_0_1, [RH, Score=758, Expect=0.0]} {RNA1509_1683} {RNA1310_5586.1} {RNA815_1778.1}
19. MligTC455_24489 5045 105.1 Mlig455_022116

Neo: -

Age: -

 ATP2B2 1.82 - - - - 0.954 0.866 Mlig455_022116 {REF} {Length: 4646} {TRANSSPLICED} {Pfam: Cation transporting ATPase, C-terminus [PF00689.23, score=154.1]; E1-E2 ATPase [PF00122.22, score=109.1]; Cation transport ATPase (P-type) [PF13246.8, score=66.5]; haloacid dehalogenase-like hydrolase [PF00702.28, score=59.5]; Cation transporter/ATPase, N-terminus [PF00690.28, score=56.4]; Plasma membrane calcium transporter ATPase C terminal [PF12424.10, score=55.5]; haloacid dehalogenase-like hydrolase [PF08282.14, score=26.2]} {Human: ENSG00000157087, ATP2B2, ATPase plasma membrane Ca2+ transporting 2, [RH, Score=1271, Expect=0.0]; ENSG00000067842, ATP2B3, ATPase plasma membrane Ca2+ transporting 3, [RH, Score=1267, Expect=0.0]; ENSG00000058668, ATP2B4, ATPase plasma membrane Ca2+ transporting 4, [RH, Score=1241, Expect=0.0]; ENSG00000070961, ATP2B1, ATPase plasma membrane Ca2+ transporting 1, [RH, Score=1219, Expect=0.0]} {Mouse: ENSMUSG00000031376, Atp2b3, ATPase, Ca++ transporting, plasma membrane 3, [RH, Score=1263, Expect=0.0]; ENSMUSG00000030302, Atp2b2, ATPase, Ca++ transporting, plasma membrane 2, [RH, Score=1261, Expect=0.0]; ENSMUSG00000019943, Atp2b1, ATPase, Ca++ transporting, plasma membrane 1, [RH, Score=1229, Expect=0.0]; ENSMUSG00000026463, Atp2b4, ATPase, Ca++ transporting, plasma membrane 4, [RH, Score=1202, Expect=0.0]} {Dmel: FBgn0259214, PMCA, plasma membrane calcium ATPase, [RH, Score=1310, Expect=0.0]} {Celegans: WBGene00003153, mca-3, Calcium-transporting ATPase, [RH, Score=1270, Expect=0.0]} {Smed: dd_Smed_v6_4145_0_1, dd_Smed_v6_4145_0_1, [RH, Score=1351, Expect=0.0]} {RNA1509_15163, RNA1509_374, RNA1509_45766} {RNA1310_4479.2, RNA1509_15163, RNA1509_45766} {RNA1509_15163, RNA1509_45766, RNA815_368.1}
20. MligTC455_47062 5095 106.14 Mlig455_009982

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.644

 ALPL 1.812 - 0.855 - - 0.957 - Mlig455_009982 {REF} {Length: 3334} {Pfam: Alkaline phosphatase [PF00245.22, score=397.2]} {Human: ENSG00000162551, ALPL, alkaline phosphatase, liver/bone/kidney, [Score=385, Expect=4e-127]} {Mouse: ENSMUSG00000028766, Alpl, alkaline phosphatase, liver/bone/kidney, [Score=377, Expect=2e-124]} {Dmel: FBgn0033423, CG1809, [RH, Score=327, Expect=5e-105]} {Smed: dd_Smed_v6_8942_0_1, dd_Smed_v6_8942_0_1, [RH, Score=326, Expect=9e-105]} {RNA1509_2387, RNA1509_26918, RNA1509_58331, RNA1509_6184} {RNA1310_4484.1, RNA1509_26918, RNA1509_58331, RNA1509_6184} {RNA1509_26918, RNA1509_58331, RNA1509_6184, RNA815_1537}
21. MligTC455_22234 6560 136.67 Mlig455_006130

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.373

 EFHC2 1.776 - - - - 0.826 0.950 Mlig455_006130 {REF} {Length: 3115} {Pfam: DUF1126 PH-like domain [PF06565.14, score=338.3]; EF hand [PF00036.34, score=18.1]} {Human: ENSG00000183690, EFHC2, EF-hand domain containing 2, [RH, Score=658, Expect=0.0]} {Mouse: ENSMUSG00000025038, Efhc2, EF-hand domain (C-terminal) containing 2, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0034487, Efhc1.2, EF-hand domain containing 1.2, [RH, Score=418, Expect=3e-135]} {Celegans: WBGene00013028, efhc-1, EF-Hand domain-Containing protein 1 homolog, [Score=97.8, Expect=2e-21]} {Smed: dd_Smed_v6_6035_0_1, dd_Smed_v6_6035_0_1, [RH, Score=830, Expect=0.0]} {RNA1509_10098, RNA1509_25996, RNA1509_36596, RNA1509_6224, RNA1509_7453} {RNA1310_5674, RNA1509_10098, RNA1509_25996, RNA1509_36596, RNA1509_6224, RNA1509_7453} {RNA1509_10098, RNA1509_25996, RNA1509_36596, RNA1509_6224, RNA1509_7453, RNA815_1927.1}
22. MligTC455_44849 3056 63.66 Mlig455_014245

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.313

 LEXM 1.758 - 0.801 - - 0.957 - Mlig455_014245 {REF} {Length: 2724} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1} {RNA815_5377}
23. MligTC455_35727 864 18 Mlig455_067627

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.342

 FRMD5 1.72 - - - 0.752 0.968 - Mlig455_067627 {REF} {Length: 4848} {TRANSSPLICED} {Pfam: FERM central domain [PF00373.20, score=53.4]; FERM C-terminal PH-like domain [PF09380.12, score=47.2]; FERM N-terminal domain [PF09379.12, score=40.2]} {Human: ENSG00000171877, FRMD5, FERM domain containing 5, [Score=208, Expect=2e-59]; ENSG00000172159, FRMD3, FERM domain containing 3, [Score=207, Expect=8e-59]} {Mouse: ENSMUSG00000049122, Frmd3, FERM domain containing 3, [Score=213, Expect=3e-61]; ENSMUSG00000027238, Frmd5, FERM domain containing 5, [Score=207, Expect=2e-59]} {Dmel: FBgn0032225, CG5022, [RH, Score=208, Expect=3e-59]} {Celegans: WBGene00001491, frm-4, FERM domain (Protein4.1-ezrin-radixin-moesin) family, [Score=155, Expect=3e-40]} {Smed: dd_Smed_v6_6227_0_1, dd_Smed_v6_6227_0_1, [RH, Score=297, Expect=2e-92]} {RNA1509_19270, RNA1509_8473} {RNA1310_22678, RNA1509_19270} {RNA1509_19270, RNA815_15509.1}
24. MligTC455_16002 752 15.67 Mlig455_062545

Neo: -

Age: -

 TTC16 1.7 - - 0.747 - 0.953 - Mlig455_062545 {REF} {Length: 2280} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=82.7]; Tetratricopeptide repeat [PF00515.30, score=64.9]; TPR repeat [PF13414.8, score=58.1]; Tetratricopeptide repeat [PF13432.8, score=57.0]; Tetratricopeptide repeat [PF13181.8, score=56.4]; Tetratricopeptide repeat [PF13428.8, score=54.2]; Tetratricopeptide repeat [PF14559.8, score=42.2]; Tetratricopeptide repeat [PF13424.8, score=41.4]; Tetratricopeptide repeat [PF13371.8, score=32.2]; Tetratricopeptide repeat [PF13176.8, score=31.2]; Tetratricopeptide repeat [PF13431.8, score=24.0]; NMDA receptor-regulated protein 1 [PF12569.10, score=23.7]; Tetratricopeptide repeat [PF13174.8, score=21.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.2]} {Human: ENSG00000167094, TTC16, tetratricopeptide repeat domain 16, [RH, Score=291, Expect=3e-86]} {Mouse: ENSMUSG00000039021, Ttc16, tetratricopeptide repeat domain 16, [RH, Score=295, Expect=9e-89]} {Celegans: WBGene00000500, chn-1, C-term of Hsp70-iNteracting protein (CHIP family); Hsp70-interacting protein, [Score=50.8, Expect=1e-06]} {Smed: dd_Smed_v6_11894_0_1, dd_Smed_v6_11894_0_1, [RH, Score=447, Expect=1e-147]} {RNA1509_9009} {RNA1310_10645.1, RNA1509_9009} {RNA1509_9009, RNA815_3627}
25. MligTC455_49142 139 2.9 Mlig455_021656

Neo: -

Age: -

 1.679 - - - 0.707 0.972 - Mlig455_021656 {REF} {Length: 2413} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=49.6]} {Smed: dd_Smed_v6_13233_0_1, dd_Smed_v6_13233_0_1, [Score=60.1, Expect=4e-09]} {RNA1509_11962} {RNA1310_8951.1}
26. MligTC455_21140 812 16.92 Mlig455_012908, Mlig455_012918

Neo: -

Age: Down-Up-Down

 AJM1 0.971 - - - - 0.971 -

Mlig455_012908 {REF} {Length: 6957} {Human: ENSG00000232434, AJM1, apical junction component 1 homolog, [Score=62.4, Expect=8e-09]} {Mouse: ENSMUSG00000029419, Ajm1, apical junction component 1, [Score=63.9, Expect=2e-09]} {Dmel: FBgn0261802, CG42748, [Score=57.0, Expect=2e-07]} {RNA1509_13411, RNA1509_13662} {RNA1310_646, RNA1509_13411} {RNA1509_13411, RNA815_244}

Mlig455_012918 {REF} {Length: 6960} {Human: ENSG00000232434, AJM1, apical junction component 1 homolog, [Score=62.4, Expect=7e-09]} {Mouse: ENSMUSG00000029419, Ajm1, apical junction component 1, [Score=63.9, Expect=2e-09]} {Dmel: FBgn0261802, CG42748, [Score=57.0, Expect=1e-07]} {RNA1509_13662} {RNA1310_646} {RNA815_244}
27. MligTC455_20959 140 2.92 Mlig455_047580

Neo: -

Age: -

 0.962 - - - - 0.962 - Mlig455_047580 {REF} {Length: 2548} {RNA1509_41536} {RNA1310_20925} {RNA815_17486.1}
28. MligTC455_43063 5711 118.98 Mlig455_008727, Mlig455_063588, Mlig455_063597

Neo: -

Age: logFC(26M/2M)=-0.428

Region-enriched R8: 1.085/0.01787

 GGT1 0.962 - - - - 0.962 -

Mlig455_008727 {REF} {Length: 2577} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=528.5]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=419, Expect=8e-139]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [RH, Score=392, Expect=2e-128]} {Dmel: FBgn0025837, CG17636, [RH, Score=352, Expect=7e-113]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=387, Expect=6e-126]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=443, Expect=7e-148]} {RNA1509_10553, RNA1509_2471, RNA1509_29196} {RNA1310_8769, RNA1509_10553, RNA1509_29196} {RNA1509_10553, RNA1509_29196, RNA815_2837}

Mlig455_063588 {REF} {Length: 2595} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=502.5]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=409, Expect=1e-136]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [Score=381, Expect=5e-126]} {Dmel: FBgn0025837, CG17636, [RH, Score=348, Expect=4e-113]} {Celegans: WBGene00016906, C53D5.5, [Score=357, Expect=3e-116]} {Smed: dd_Smed_v6_4591_0_2, dd_Smed_v6_4591_0_2, [RH, Score=402, Expect=5e-134]} {RNA1509_2471} {RNA1310_8769} {RNA815_2837}

Mlig455_063597 {REF} {Length: 2607} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=527.1]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=417, Expect=4e-139]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [Score=389, Expect=3e-128]} {Dmel: FBgn0025837, CG17636, [RH, Score=351, Expect=2e-113]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=386, Expect=3e-126]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=443, Expect=4e-149]} {RNA1509_2471, RNA1509_44409} {RNA1310_8769, RNA1509_44409} {RNA1509_44409, RNA815_2837}
29. MligTC455_26986 157 3.28 Mlig455_058044

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.496

 0.961 - - - - 0.961 - Mlig455_058044 {REF} {Length: 3183} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=51.3]; Ceramide kinase C-terminal domain [PF19280.1, score=22.6]} {Mouse: ENSMUSG00000075256, Cerkl, ceramide kinase-like, [Score=55.1, Expect=2e-07]} {Dmel: FBgn0037315, Cerk, Ceramide kinase, [Score=52.4, Expect=1e-06]} {RNA1509_33630, RNA1509_39108} {RNA1310_4577, RNA1509_33630, RNA1509_39108} {RNA1509_33630, RNA1509_39108, RNA815_1173}
30. MligTC455_44561 1920 40 Mlig455_057194

Neo: -

Age: logFC(26M/2M)=0.185

 NBR1 0.961 - - - - 0.961 - Mlig455_057194 {REF} {Length: 3269} {Pfam: Zinc finger, ZZ type [PF00569.19, score=41.7]; UBA/TS-N domain [PF00627.33, score=19.6]} {Human: ENSG00000188554, NBR1, NBR1, autophagy cargo receptor, [RH, Score=60.5, Expect=1e-08]} {Mouse: ENSMUSG00000015837, Sqstm1, sequestosome 1, [Score=64.7, Expect=2e-10]} {Dmel: FBgn0003231, ref(2)P, refractory to sigma P, [Score=55.5, Expect=1e-07]} {Celegans: WBGene00011737, sqst-1, SeQueSTosome related, [RH, Score=62.8, Expect=6e-10]} {Smed: dd_Smed_v6_2812_0_1, dd_Smed_v6_2812_0_1, [RH, Score=54.7, Expect=7e-08]} {RNA1509_10260, RNA1509_33571} {RNA1310_6559, RNA1509_10260, RNA1509_33571} {RNA1509_10260, RNA1509_33571, RNA815_1176}
31. MligTC455_28521 992 20.67 Mlig455_046502

Neo: -

Age: -

 0.958 - - - - 0.958 - Mlig455_046502 {REF} {Length: 2752} {Dmel: FBgn0031174, CG1486, [Score=81.3, Expect=3e-17]} {Celegans: WBGene00007593, C14H10.3, [Score=87.4, Expect=3e-19]} {Smed: dd_Smed_v6_8663_0_1, dd_Smed_v6_8663_0_1, [Score=84.0, Expect=3e-18]} {RNA1509_19144} {RNA1310_30735} {RNA815_1517}
32. MligTC455_35296 3716 77.42 Mlig455_021730

Neo: -

Age: logFC(26M/2M)=-0.211

 RAB11B 0.958 - - - - - 0.958 Mlig455_021730 {REF} {Length: 4827} {Pfam: Ras family [PF00071.24, score=161.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=109.2]; ADP-ribosylation factor family [PF00025.23, score=50.2]; 50S ribosome-binding GTPase [PF01926.25, score=28.2]; RsgA GTPase [PF03193.18, score=19.7]} {Human: ENSG00000185236, RAB11B, RAB11B, member RAS oncogene family, [Score=146, Expect=6e-39]} {Mouse: ENSMUSG00000077450, Rab11b, RAB11B, member RAS oncogene family, [Score=145, Expect=5e-39]; ENSMUSG00000079657, Rab26, RAB26, member RAS oncogene family, [Score=139, Expect=1e-35]; ENSMUSG00000004771, Rab11a, RAB11A, member RAS oncogene family, [Score=138, Expect=2e-36]} {Dmel: FBgn0015790, Rab11, [Score=139, Expect=6e-37]} {Celegans: WBGene00004271, rab-7, RAB family, [Score=135, Expect=8e-36]} {Smed: dd_Smed_v6_4001_0_1, dd_Smed_v6_4001_0_1, [Score=136, Expect=3e-36]} {RNA1509_48652, RNA1509_48880, RNA1509_8793, RNA1509_9768} {RNA1310_4344.1, RNA1509_48652, RNA1509_48880, RNA1509_8793} {RNA1509_48652, RNA1509_48880, RNA1509_8793, RNA815_5085}
33. MligTC455_41699 427 8.9 Mlig455_004636

Neo: -

Age: -

 CYP2U1 0.953 - - - - 0.953 - Mlig455_004636 {REF} {Length: 2637} {Pfam: Cytochrome P450 [PF00067.24, score=213.9]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=177, Expect=4e-53]} {Mouse: ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=171, Expect=3e-49]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=171, Expect=3e-49]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=167, Expect=1e-47]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=119, Expect=4e-30]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [Score=151, Expect=5e-42]} {Smed: dd_Smed_v6_2351_0_2, dd_Smed_v6_2351_0_2, [Score=187, Expect=1e-55]} {RNA1509_44189} {RNA1310_1872.1} {RNA815_585.1}

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