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Results for MligTC455_18833

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_18833 771 16.06 Mlig455_005836

Neo: -

Age: logFC(26M/2M)=-0.422

Region-enriched R2: 2.455/0.00029

Mlig455_005836 {REF} {Length: 486} {RNA1509_25076} {RNA1310_75647, RNA1509_25076} {RNA1509_25076, RNA815_38932.1}

Cumulative graph for MligTC455_18833

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.173 4.146 0.40868 1.00000
RegionR2 2.455 4.146 0.00000 0.00029
RegionR3 -0.931 4.146 0.10944 0.57601
RegionR4 -1.727 4.146 0.01499 0.08244
RegionR5 -0.822 4.146 0.13957 0.38434
RegionR6 -0.013 4.146 0.99086 1.00000
RegionR7 1.485 4.146 0.00365 0.08802
RegionR8 0.728 4.146 0.27066 0.89401

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.01 4.146 0.99505 1.00000
RegenerationR2 -1.038 4.146 0.05478 0.38580
RegenerationR3 -0.383 4.146 0.54893 0.88312
RegenerationR4 0.133 4.146 0.83750 1.00000
RegenerationR5 -0.06 4.146 0.92307 1.00000
RegenerationR6 -1.258 4.146 0.05547 0.29544
RegenerationBL -2.067 4.146 0.00514 0.06702
RegenerationTP -0.372 4.146 0.54770 0.93135


Genes with expression patterns similar to MligTC455_18833

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_18833 771 16.06 Mlig455_005836

Neo: -

Age: logFC(26M/2M)=-0.422

Region-enriched R2: 2.455/0.00029

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_005836 {REF} {Length: 486} {RNA1509_25076} {RNA1310_75647, RNA1509_25076} {RNA1509_25076, RNA815_38932.1}
2. MligTC455_45542 1297 27.03 Mlig455_054862

Neo: -

Age: -

Region-specific R2: 3.717

Region-enriched R2: 3.775/0.00000

5.441 0.851 0.934 0.874 0.890 0.959 0.933 Mlig455_054862 {REF} {Length: 827} {RNA1509_22827, RNA1509_33579} {RNA1310_53394, RNA1509_22827, RNA1509_33579} {RNA1509_22827, RNA1509_33579, RNA815_31276}
3. MligTC455_38162 710 14.8 Mlig455_045004

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.269

Region-enriched R2: 5.838/0.00000

Regeneration-downregulated R2: -4.412

Regeneration-depleted R2: -4.412

5.374 0.914 0.956 0.894 0.940 0.949 0.721 Mlig455_045004 {REF} {Length: 659} {Smed: dd_Smed_v6_4046_0_1, dd_Smed_v6_4046_0_1, [Score=57.8, Expect=2e-12]} {RNA1509_50998, RNA1509_57106} {RNA1310_56015, RNA1509_50998, RNA1509_57106} {RNA1509_50998, RNA1509_57106, RNA815_29915}
4. MligTC455_51386 763 15.89 Mlig455_041336, Mlig455_056222

Neo: -

Age: -

Region-enriched R2: 3.643/0.00016

HPGDS 5.373 0.854 0.940 0.967 0.915 0.905 0.792

Mlig455_041336 {REF} {Length: 1363} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=46.9]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=34.8]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=23.3]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=22.4]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [Score=74.7, Expect=2e-15]} {Mouse: ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [Score=82.4, Expect=2e-18]} {Celegans: WBGene00001756, gst-8, Probable glutathione S-transferase 8, [Score=92.8, Expect=2e-22]} {Smed: dd_Smed_v6_1206_0_1, dd_Smed_v6_1206_0_1, [Score=79.0, Expect=2e-17]} {RNA1509_56224} {RNA1310_31890.2} {RNA815_14778}

Mlig455_056222 {REF} {Length: 1343} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=62.1]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=34.8]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=31.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=23.4]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=22.5]; Glutathione S-transferase, C-terminal domain [PF13410.8, score=21.8]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [Score=78.2, Expect=8e-17]} {Mouse: ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [Score=85.5, Expect=1e-19]} {Celegans: WBGene00001750, gst-2, Glutathione S-transferase 2, [RH, Score=96.7, Expect=3e-24]} {Smed: dd_Smed_v6_1206_0_1, dd_Smed_v6_1206_0_1, [Score=84.3, Expect=2e-19]} {RNA1509_56224} {RNA1310_31890.2} {RNA815_14778}
5. MligTC455_44525 3358 69.96 Mlig455_004678, Mlig455_004741, Mlig455_004755, Mlig455_004840

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.742

Region-enriched R2: 10.296/0.00000
Region-enriched R3: 3.568/0.01807

5.315 0.845 0.976 0.946 0.957 0.852 0.739

Mlig455_004678 {REF} {Length: 845} {RNA1509_25712} {RNA1310_68954.2} {RNA815_35323}

Mlig455_004741 {REF} {Length: 961} {RNA1509_25712} {RNA1310_68954.1} {RNA815_35323}

Mlig455_004755 {REF} {Length: 1059} {RNA1509_25712} {RNA1310_68954.2} {RNA815_35323}

Mlig455_004840 {REF} {Length: 918} {RNA1509_25712, RNA1509_29691} {RNA1310_68954.2, RNA1509_25712, RNA1509_29691} {RNA1509_25712, RNA1509_29691, RNA815_35323}
6. MligTC455_38949 105 2.19 Mlig455_065209

Neo: -

Age: -

Region-specific R2: 7.633

Region-enriched R2: 10.088/0.00000

5.301 0.867 0.974 0.948 0.837 0.947 0.728 Mlig455_065209 {REF} {Length: 591} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=23.2]} {RNA1509_44618} {RNA1310_63839, RNA1509_44618} {RNA1509_44618, RNA815_35329}
7. MligTC455_17177 103 2.15 Mlig455_048992, Mlig455_049009

Neo: -

Age: Down-Down-Up

5.272 0.862 0.961 0.946 0.823 0.949 0.731

Mlig455_048992 {REF} {Length: 1836} {RNA1509_44702} {RNA1310_14743, RNA1509_44702} {RNA1509_44702, RNA815_20669.1}

Mlig455_049009 {REF} {Length: 1823} {RNA1509_44702} {RNA1310_14743} {RNA815_20669.1}
8. MligTC455_24407 222 4.63 Mlig455_044026

Neo: -

Age: Down-Up-Up

Region-specific R2: 3.725

Region-enriched R2: 3.414/0.00001

5.267 0.825 0.983 0.912 0.825 0.954 0.768 Mlig455_044026 {REF} {Length: 503} {RNA1509_54091} {RNA1310_68348.1} {RNA815_33570.1}
9. MligTC455_29119 68 1.42 Mlig455_050458

Neo: -

Age: -

Region-enriched R2: 5.525/0.01281

5.266 0.869 0.973 0.855 0.783 0.949 0.837 Mlig455_050458 {REF} {Length: 624} {RNA1509_53840} {RNA1310_67192} {RNA815_27042}
10. MligTC455_19552 288 6 Mlig455_055936, Mlig455_068188

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.424

Region-specific R2: 6.302

Region-enriched R2: 4.919/0.00633

Regeneration-depleted R4: -5.607
Regeneration-depleted R2: -3.270

5.25 0.883 0.978 0.848 0.835 0.924 0.782

Mlig455_055936 {REF} {Length: 665} {RNA1310_71052} {RNA815_36745}

Mlig455_068188 {REF} {Length: 714} {RNA1310_71052} {RNA815_36745}
11. MligTC455_47420 218 4.54 Mlig455_017159, Mlig455_048110

Neo: -

Age: -

Region-specific R2: 6.469

Region-enriched R2: 5.851/0.00135

5.249 0.876 0.966 0.959 0.820 0.918 0.710

Mlig455_017159 {REF} {Length: 1062} {RNA1509_35349} {RNA1310_81586}

Mlig455_048110 {REF} {Length: 527} {RNA1310_81586}
12. MligTC455_50347 549 11.43 Mlig455_012382

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.390

Region-enriched R2: 6.623/0.00000

5.241 0.798 0.971 0.935 0.930 0.789 0.818 Mlig455_012382 {REF} {Length: 797} {RNA1509_48155} {RNA1310_70969.2, RNA1509_48155} {RNA1509_48155, RNA815_39712}
13. MligTC455_45912 1103 22.98 Mlig455_006912

Neo: -

Age: -

Region-specific R2: 3.366

Region-enriched R2: 1.790/0.00307

5.24 0.839 0.978 0.777 0.860 0.941 0.845 Mlig455_006912 {REF} {Length: 1066} {RNA1509_32903, RNA1509_42927} {RNA1310_38334, RNA1509_42927} {RNA1509_42927, RNA815_18393}
14. MligTC455_17178 54 1.12 Mlig455_067758

Neo: -

Age: -

Region-enriched R2: 7.471/0.00007

5.214 0.858 0.949 0.953 0.828 0.921 0.705 Mlig455_067758 {REF} {Length: 2301} {RNA1509_44702} {RNA1310_14743} {RNA815_20669.1}
15. MligTC455_37710 5814 121.13 Mlig455_023529, Mlig455_023635

Neo: -

Age: logFC(26M/2M)=0.275

Region-enriched R7: 2.382/0.00159

Regeneration-downregulated BL: -3.544

Regeneration-depleted BL: -3.544

5.21 0.819 0.853 0.927 0.748 0.902 0.961

Mlig455_023529 {REF} {Length: 1292} {RNA1509_13958} {RNA1310_54113} {RNA815_27382.1}

Mlig455_023635 {REF} {Length: 673} {RNA1509_13958, RNA1509_22495, RNA1509_30469, RNA1509_39550} {RNA1310_54113, RNA1509_13958, RNA1509_22495, RNA1509_30469, RNA1509_39550} {RNA1509_13958, RNA1509_22495, RNA1509_30469, RNA1509_39550, RNA815_27382.1}
16. MligTC455_52629 472 9.83 Mlig455_059435

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.775

Region-enriched R2: 6.727/0.00002

5.188 0.809 0.979 0.902 0.834 0.933 0.731 Mlig455_059435 {REF} {Length: 726} {RNA1509_48505} {RNA1310_62885} {RNA815_39881}
17. MligTC455_41587 2912 60.66 Mlig455_018983, Mlig455_055720

Neo: -

Age: Down-Down-Up

Region-specific R2: 3.258

Region-enriched R2: 2.529/0.00000

Regeneration-downregulated BL: -2.793

Regeneration-depleted BL: -2.793

5.163 0.960 0.870 0.861 0.822 0.715 0.935

Mlig455_018983 {REF} {Length: 871} {RNA1509_9390} {RNA1310_40276} {RNA815_19143}

Mlig455_055720 {REF} {Length: 988} {RNA1509_9390} {RNA1310_40276} {RNA815_19143}
18. MligTC455_42314 406 8.46 Mlig455_052727

Neo: -

Age: -

Region-enriched R2: 4.230/0.00183

5.144 0.861 0.882 0.776 0.824 0.957 0.844 Mlig455_052727 {REF} {Length: 1339} {Pfam: Hyaluronidase protein (HylP) [PF07212.13, score=19.1]} {RNA1509_51722} {RNA1310_50605} {RNA815_15783.1}
19. MligTC455_40444 2996 62.42 Mlig455_039527, Mlig455_051318

Neo: -

Age: Down-Up-Down

5.083 0.844 0.951 0.796 0.789 0.878 0.825

Mlig455_039527 {REF} {Length: 710} {RNA1509_7655} {RNA1310_63393} {RNA815_30324}

Mlig455_051318 {REF} {Length: 721} {RNA1509_7655} {RNA1310_63393, RNA1509_7655} {RNA1509_7655, RNA815_30324}
20. MligTC455_33277 1450 30.2 Mlig455_031182

Neo: -

Age: -

Region-specific R2: 3.361

Region-enriched R2: 2.732/0.00000

TRO 5.008 0.707 0.872 0.747 0.794 0.918 0.970 Mlig455_031182 {REF} {Length: 1600} {Human: ENSG00000067445, TRO, trophinin, [Score=52.8, Expect=3e-08]} {Smed: dd_Smed_v6_1015_0_1, dd_Smed_v6_1015_0_1, [RH, Score=43.9, Expect=3e-06]} {RNA1509_34972} {RNA1310_37320, RNA1509_34972} {RNA1509_34972, RNA815_25574}
21. MligTC455_12512 80 1.68 Mlig455_017689

Neo: -

Age: -

4.998 0.863 0.969 0.809 0.719 0.915 0.723 Mlig455_017689 {REF} {Length: 934} {RNA1310_37507} {RNA815_32171}
22. MligTC455_34369 112 2.34 Mlig455_015308, Mlig455_015354, Mlig455_036248, Mlig455_068737, Mlig455_070110

Neo: -

Age: Up-Down-Up

Region-enriched R2: 5.462/0.00546

4.857 0.880 0.720 0.950 0.718 0.769 0.820

Mlig455_015308 {REF} {Length: 1459} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.9]} {RNA1310_34740} {RNA815_15663}

Mlig455_015354 {REF} {Length: 1446} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=66.3]; Sialidase, N-terminal domain [PF02973.18, score=18.5]} {RNA1310_34740} {RNA815_15663}

Mlig455_036248 {REF} {Length: 2111} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=120.9]; Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=28.5]; PAN domain [PF00024.28, score=19.9]} {RNA1509_45496} {RNA1310_2539.1} {RNA815_252.1}

Mlig455_068737 {REF} {Length: 1096} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=68.3]; Sialidase, N-terminal domain [PF02973.18, score=19.9]} {RNA1310_34740} {RNA815_37905}

Mlig455_070110 {REF} {Length: 1340} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=109.6]} {RNA1509_32599} {RNA1310_1659} {RNA815_252.1}
23. MligTC455_17299 538 11.21 Mlig455_036559, Mlig455_057787

Neo: -

Age: -

Region-enriched R2: 5.046/0.00000
Region-enriched R3: 3.527/0.00004

4.696 0.728 0.950 0.745 0.727 0.834 0.712

Mlig455_036559 {REF} {Length: 718} {RNA1509_57277} {RNA1310_52579, RNA1509_57277} {RNA1509_57277, RNA815_26706}

Mlig455_057787 {REF} {Length: 741} {RNA1509_57277} {RNA1310_52579} {RNA815_26706}
24. MligTC455_09510 314 6.55 Mlig455_001134, Mlig455_042048

Neo: -

Age: -

Region-specific R2: 5.291

Region-enriched R2: 5.151/0.00029

4.52 0.909 0.923 0.954 0.811 0.923 -

Mlig455_001134 {REF} {Length: 485} {Pfam: Fingers domain of DNA polymerase lambda [PF10391.11, score=26.9]} {RNA1310_8738.1} {RNA815_21682.1}

Mlig455_042048 {REF} {Length: 1550} {Pfam: Fingers domain of DNA polymerase lambda [PF10391.11, score=32.1]} {Dmel: FBgn0036416, CG7924, [RH, Score=61.2, Expect=1e-10]} {RNA1509_51261} {RNA1310_8738.1} {RNA815_21682.1}
25. MligTC455_21033 1129 23.52 Mlig455_010672

Neo: -

Age: logFC(26M/2M)=0.356

Region-specific R2: 3.326

Region-enriched R2: 2.739/0.00000

Regeneration-downregulated R2: -1.967

Regeneration-depleted R2: -1.967

4.513 0.951 0.970 0.909 0.817 0.866 - Mlig455_010672 {REF} {Length: 829} {RNA1509_30331, RNA1509_45731} {RNA1310_60944, RNA1509_30331, RNA1509_45731} {RNA1509_30331, RNA1509_45731, RNA815_27381.1}
26. MligTC455_16847 1240 25.83 Mlig455_051898, Mlig455_053146

Neo: -

Age: Down-Up-Down

Region-specific R2: 5.478

Region-enriched R2: 5.690/0.00000

PRSS33 4.476 - 0.907 0.923 0.981 0.930 0.735

Mlig455_051898 {REF} {Length: 1360} {Pfam: Trypsin [PF00089.28, score=189.8]; Domain of unknown function (DUF1986) [PF09342.13, score=27.3]; Trypsin-like peptidase domain [PF13365.8, score=26.9]} {Human: ENSG00000103355, PRSS33, serine protease 33, [Score=159, Expect=4e-46]} {Mouse: ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=153, Expect=9e-41]; ENSMUSG00000037129, Tmprss13, transmembrane protease, serine 13, [Score=150, Expect=2e-40]; ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [Score=148, Expect=6e-39]; ENSMUSG00000022857, Tmprss15, transmembrane protease, serine 15, [Score=147, Expect=2e-38]} {Dmel: FBgn0036287, CG10663, [Score=146, Expect=1e-38]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [Score=124, Expect=6e-31]} {Smed: dd_Smed_v6_10267_0_1, dd_Smed_v6_10267_0_1, [Score=178, Expect=4e-53]} {RNA1509_29335} {RNA1310_23561} {RNA815_9840}

Mlig455_053146 {REF} {Length: 1448} {Pfam: Trypsin [PF00089.28, score=189.8]; Domain of unknown function (DUF1986) [PF09342.13, score=27.3]; Trypsin-like peptidase domain [PF13365.8, score=26.9]} {Human: ENSG00000103355, PRSS33, serine protease 33, [Score=159, Expect=4e-46]} {Mouse: ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=153, Expect=9e-41]; ENSMUSG00000037129, Tmprss13, transmembrane protease, serine 13, [Score=150, Expect=2e-40]; ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [Score=148, Expect=6e-39]; ENSMUSG00000022857, Tmprss15, transmembrane protease, serine 15, [Score=147, Expect=2e-38]} {Dmel: FBgn0036287, CG10663, [Score=146, Expect=1e-38]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [Score=124, Expect=6e-31]} {Smed: dd_Smed_v6_10267_0_1, dd_Smed_v6_10267_0_1, [Score=178, Expect=4e-53]} {RNA1509_26566, RNA1509_29335} {RNA1310_23561, RNA1509_26566, RNA1509_29335} {RNA1509_26566, RNA1509_29335, RNA815_9840}
27. MligTC455_43963 1010 21.04 Mlig455_015437

Neo: -

Age: Down-Down-Up

Region-enriched R2: 2.083/0.01168

4.436 0.942 0.990 0.847 - 0.807 0.850 Mlig455_015437 {REF} {Length: 612} {RNA1509_32160} {RNA1310_60746, RNA1509_32160} {RNA1509_32160, RNA815_30740}
28. MligTC455_48609 3538 73.7 Mlig455_037431, Mlig455_037454, Mlig455_037501

Neo: -

Age: -

Region-specific R2: 3.134

Region-enriched R2: 1.985/0.00000

Regeneration-downregulated BL: -2.003

Regeneration-depleted BL: -2.003

CAPN5 4.436 - 0.928 0.848 0.845 0.865 0.950

Mlig455_037431 {REF} {Length: 2455} {Pfam: Calpain family cysteine protease [PF00648.23, score=124.0]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=106, Expect=2e-23]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=103, Expect=1e-22]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=2e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=103, Expect=5e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}

Mlig455_037454 {REF} {Length: 1043} {RNA1509_15549} {RNA1310_57168} {RNA815_30048}

Mlig455_037501 {REF} {Length: 2687} {Pfam: Calpain family cysteine protease [PF00648.23, score=123.7]} {Human: ENSG00000149260, CAPN5, calpain 5, [Score=108, Expect=6e-24]} {Mouse: ENSMUSG00000035547, Capn5, calpain 5, [Score=105, Expect=5e-23]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=86.3, Expect=2e-17]} {Celegans: WBGene00006606, tra-3, Calpain-5, [Score=120, Expect=3e-28]} {Smed: dd_Smed_v6_8673_0_1, dd_Smed_v6_8673_0_1, [Score=104, Expect=4e-23]} {RNA1509_27234} {RNA1310_12131} {RNA815_7478.1}
29. MligTC455_35813 35 0.73 Mlig455_013562, Mlig455_013615

Neo: -

Age: -

Region-enriched R2: 7.733/0.00085

NPR2 4.412 0.863 0.963 0.874 0.760 0.952 -

Mlig455_013562 {REF} {Length: 3105} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=187.6]; Nitrate and nitrite sensing [PF08376.12, score=108.9]; Heme NO binding associated [PF07701.16, score=29.1]} {Human: ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=251, Expect=2e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=247, Expect=6e-69]; ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=241, Expect=1e-66]} {Mouse: ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=252, Expect=1e-73]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=248, Expect=2e-69]} {Dmel: FBgn0053958, CG33958, [Score=330, Expect=3e-102]} {Celegans: WBGene00001533, gcy-6, Receptor-type guanylate cyclase gcy-6, [Score=231, Expect=7e-64]} {Smed: dd_Smed_v6_11767_0_1, dd_Smed_v6_11767_0_1, [Score=244, Expect=3e-68]} {RNA1310_16282} {RNA815_27869}

Mlig455_013615 {REF} {Length: 2993} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=187.7]; Nitrate and nitrite sensing [PF08376.12, score=109.5]; Heme NO binding associated [PF07701.16, score=29.1]} {Human: ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=251, Expect=2e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=246, Expect=8e-69]; ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=241, Expect=1e-66]} {Mouse: ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=252, Expect=9e-74]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=247, Expect=2e-69]} {Dmel: FBgn0053958, CG33958, [Score=331, Expect=1e-102]} {Celegans: WBGene00001533, gcy-6, Receptor-type guanylate cyclase gcy-6, [Score=231, Expect=8e-64]} {Smed: dd_Smed_v6_11767_0_1, dd_Smed_v6_11767_0_1, [Score=244, Expect=3e-68]} {RNA1310_16282} {RNA815_33407}
30. MligTC455_47780 214 4.46 Mlig455_018842, Mlig455_018853

Neo: -

Age: -

4.4 0.766 0.973 0.934 0.804 0.923 -

Mlig455_018842 {REF} {Length: 500} {RNA1509_48336} {RNA1310_73351} {RNA815_41082}

Mlig455_018853 {REF} {Length: 593} {RNA1509_48336} {RNA1310_73351, RNA1509_48336} {RNA1509_48336, RNA815_41082}
31. MligTC455_46844 1466 30.54 Mlig455_033495, Mlig455_069242

Neo: -

Age: -

Region-enriched R2: 3.929/0.00054

4.394 0.810 0.957 0.894 - 0.890 0.843

Mlig455_033495 {REF} {Length: 510} {RNA1509_52173} {RNA1310_82836} {RNA815_43043}

Mlig455_069242 {REF} {Length: 707} {RNA1509_33548, RNA1509_52173} {RNA1310_82836, RNA1509_33548, RNA1509_52173} {RNA1509_33548, RNA1509_52173, RNA815_43043}
32. MligTC455_17021 49 1.02 Mlig455_030263

Neo: -

Age: -

4.376 0.866 0.960 0.879 - 0.886 0.785 Mlig455_030263 {REF} {Length: 566} {TRANSSPLICED} {Pfam: Galactosyltransferase [PF01762.23, score=23.7]} {Dmel: FBgn0000221, brn, brainiac, [Score=45.8, Expect=1e-06]} {RNA1310_35735} {RNA815_59866}
33. MligTC455_48714 132 2.74 Mlig455_037041

Neo: -

Age: -

Region-enriched R2: 4.531/0.00493

4.36 0.790 0.976 0.894 - 0.869 0.831 Mlig455_037041 {REF} {Length: 1099} {RNA1509_35038} {RNA1310_72135} {RNA815_37404}
34. MligTC455_45351 241 5.02 Mlig455_031191

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.622/0.00310

4.342 - 0.954 0.811 0.818 0.938 0.821 Mlig455_031191 {REF} {Length: 2855} {Pfam: Srg family chemoreceptor [PF02118.23, score=28.1]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=26.4]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=26.4]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=49.3, Expect=2e-06]} {Smed: dd_Smed_v6_7534_0_1, dd_Smed_v6_7534_0_1, [Score=54.7, Expect=4e-08]} {RNA1509_20184} {RNA1310_32455} {RNA815_38062}
35. MligTC455_29412 46 0.96 Mlig455_000627, Mlig455_008268, Mlig455_040614

Neo: -

Age: Up-Down-Up

4.339 - 0.920 0.952 0.838 0.906 0.723

Mlig455_000627 {REF} {Length: 1331} {RNA1310_62571} {RNA815_30942}

Mlig455_008268 {REF} {Length: 1779} {RNA1509_47298} {RNA1310_98344} {RNA815_10804.1}

Mlig455_040614 {REF} {Length: 1016}
36. MligTC455_08837 2734 56.96 Mlig455_047253, Mlig455_047306

Neo: -

Age: -

Region-specific R2: 4.689

Region-enriched R2: 4.490/0.00000
Region-enriched R3: 1.490/0.03544

4.328 0.859 0.937 0.706 0.987 0.839 -

Mlig455_047253 {REF} {Length: 3106} {TRANSSPLICED} {Pfam: Pancreatic hormone peptide [PF00159.20, score=46.0]} {Smed: dd_Smed_v6_16946_0_1, dd_Smed_v6_16946_0_1, [Score=41.6, Expect=3e-06]} {RNA1509_19067, RNA1509_27231} {RNA1310_388.2, RNA1509_19067} {RNA1509_19067, RNA815_3901}

Mlig455_047306 {REF} {Length: 3098} {Pfam: Pancreatic hormone peptide [PF00159.20, score=46.0]} {Smed: dd_Smed_v6_16946_0_1, dd_Smed_v6_16946_0_1, [Score=42.0, Expect=2e-06]} {RNA1509_27231} {RNA1310_388.2, RNA1509_27231} {RNA1509_27231, RNA815_3901}
37. MligTC455_32644 41 0.86 Mlig455_043770, Mlig455_043786

Neo: -

Age: -

Region-enriched R2: 6.705/0.00336

4.323 0.854 0.972 0.861 - 0.911 0.725

Mlig455_043770 {REF} {Length: 1011} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.8, Expect=3e-11]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}

Mlig455_043786 {REF} {Length: 1348} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
38. MligTC455_18945 41 0.86 Mlig455_031602

Neo: -

Age: -

4.315 - 0.962 0.878 0.836 0.908 0.731 Mlig455_031602 {REF} {Length: 914} {RNA1310_75361} {RNA815_24378}
39. MligTC455_43715 48 0.99 Mlig455_034191

Neo: -

Age: Down-Up-Down

Region-enriched R2: 7.969/0.00817

4.309 - 0.978 0.842 0.831 0.927 0.731 Mlig455_034191 {REF} {Length: 895} {Pfam: WSC domain [PF01822.21, score=39.9]; PAN domain [PF14295.8, score=21.0]; PAN domain [PF00024.28, score=19.9]} {RNA1310_46313} {RNA815_23250}
40. MligTC455_24406 204 4.25 Mlig455_043947

Neo: -

Age: -

Region-specific R2: 3.852

Region-enriched R2: 3.953/0.00003

4.308 0.847 0.974 0.939 0.783 0.765 - Mlig455_043947 {REF} {Length: 1609} {RNA1509_54091} {RNA1310_68348.1, RNA1509_54091} {RNA1509_54091, RNA815_33570.1}
41. MligTC455_17218 37 0.78 Mlig455_053853

Neo: -

Age: -

4.304 0.864 - 0.906 0.827 0.976 0.731 Mlig455_053853 {REF} {Length: 1743} {RNA1310_61921}
42. MligTC455_21975 1445 30.1 Mlig455_067235

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.598

Region-specific R2: 3.235

Region-enriched R2: 3.090/0.00000

BMPER 4.304 0.765 0.914 0.844 0.829 0.952 - Mlig455_067235 {REF} {Length: 21751} {Pfam: von Willebrand factor type D domain [PF00094.27, score=57.1]; C8 domain [PF08742.13, score=24.9]; Neurensin [PF14927.8, score=24.8]} {Human: ENSG00000164619, BMPER, BMP binding endothelial regulator, [Score=80.9, Expect=4e-14]; ENSG00000135253, KCP, kielin/chordin-like protein, [Score=78.6, Expect=4e-13]; ENSG00000275395, FCGBP, Fc fragment of IgG binding protein, [Score=78.6, Expect=5e-13]} {Mouse: ENSMUSG00000031963, Bmper, BMP-binding endothelial regulator, [Score=78.6, Expect=2e-13]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=226, Expect=6e-58]} {Smed: dd_Smed_v6_194_0_1, dd_Smed_v6_194_0_1, [Score=244, Expect=8e-64]} {RNA1509_13513, RNA1509_26457, RNA1509_30456, RNA1509_31, RNA1509_5282} {RNA1310_7.1, RNA1509_13513, RNA1509_26457, RNA1509_30456, RNA1509_5282} {RNA1509_13513, RNA1509_26457, RNA1509_30456, RNA1509_5282, RNA815_4}
43. MligTC455_50052 580 12.08 Mlig455_026909, Mlig455_027066

Neo: -

Age: -

Region-specific R2: 2.801

Region-enriched R2: 1.805/0.00804

STOM 4.304 0.917 0.715 0.965 - 0.829 0.878

Mlig455_026909 {REF} {Length: 1737} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=110.6]; SPFH domain-Band 7 family [PF13421.8, score=19.9]} {Human: ENSG00000148175, STOM, stomatin, [RH, Score=358, Expect=4e-124]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [RH, Score=355, Expect=4e-123]} {Dmel: FBgn0260657, CG42540, [Score=361, Expect=4e-124]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [RH, Score=380, Expect=8e-132]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [RH, Score=439, Expect=8e-157]} {RNA1509_53478} {RNA1310_8094.2} {RNA815_8739}

Mlig455_027066 {REF} {Length: 3038} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=105.6]} {Human: ENSG00000148175, STOM, stomatin, [Score=345, Expect=5e-119]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=342, Expect=6e-118]} {Dmel: FBgn0260657, CG42540, [Score=349, Expect=3e-119]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=369, Expect=4e-127]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [RH, Score=427, Expect=9e-152]} {RNA1509_53478} {RNA1310_8094.2} {RNA815_8739}
44. MligTC455_41035 366 7.62 Mlig455_000866

Neo: -

Age: logFC(26M/2M)=-0.773

Region-specific R2: 5.029

Region-enriched R2: 4.768/0.00000

4.302 - 0.968 0.929 0.807 0.839 0.759 Mlig455_000866 {REF} {Length: 1126} {Pfam: Pancreatic hormone peptide [PF00159.20, score=41.6]} {RNA1509_27581} {RNA1310_74103, RNA1509_27581} {RNA1509_27581, RNA815_38377}
45. MligTC455_43714 152 3.18 Mlig455_000684, Mlig455_000736

Neo: -

Age: -

4.293 - 0.969 0.827 0.836 0.932 0.729

Mlig455_000684 {REF} {Length: 796} {Pfam: WSC domain [PF01822.21, score=42.8]} {RNA1310_46313} {RNA815_23250}

Mlig455_000736 {REF} {Length: 797} {Pfam: WSC domain [PF01822.21, score=42.8]} {RNA1310_46313} {RNA815_23250}
46. MligTC455_50454 394 8.21 Mlig455_057487

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.517/0.00000
Region-enriched R3: 2.569/0.02892

4.289 - 0.965 0.962 0.842 0.780 0.740 Mlig455_057487 {REF} {Length: 724} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=33.5]; Nematode insulin-related peptide beta type [PF03488.16, score=20.4]} {RNA1509_58074} {RNA1310_51990} {RNA815_25071}
47. MligTC455_26356 62 1.3 Mlig455_042551

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.548

GRIK2 4.285 0.860 0.969 - 0.803 0.922 0.731 Mlig455_042551 {REF} {Length: 2917} {Pfam: Ligand-gated ion channel [PF00060.28, score=82.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=60.7]; Receptor family ligand binding region [PF01094.30, score=32.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=27.3]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=144, Expect=9e-35]; ENSG00000152208, GRID2, glutamate ionotropic receptor delta type subunit 2, [Score=141, Expect=7e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=143, Expect=1e-34]; ENSMUSG00000071424, Grid2, glutamate receptor, ionotropic, delta 2, [Score=142, Expect=2e-34]} {Dmel: FBgn0051201, GluRIIE, Glutamate receptor IIE, [Score=119, Expect=3e-27]} {Celegans: WBGene00001616, glr-5, GLutamate Receptor family (AMPA), [Score=123, Expect=2e-28]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=247, Expect=4e-74]} {RNA1310_21865} {RNA815_26044}
48. MligTC455_19079 218 4.54 Mlig455_008746, Mlig455_008760

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.705

Region-enriched R2: 6.864/0.00152

4.267 - 0.925 0.950 0.790 0.868 0.734

Mlig455_008746 {REF} {Length: 652} {RNA1310_75395.1} {RNA815_42524}

Mlig455_008760 {REF} {Length: 1051} {RNA1310_75395.1} {RNA815_42524}
49. MligTC455_41382 65 1.35 Mlig455_022554

Neo: -

Age: -

Region-enriched R2: 5.596/0.01432

4.261 0.863 0.973 - 0.764 0.930 0.731 Mlig455_022554 {REF} {Length: 503} {Pfam: Pancreatic hormone peptide [PF00159.20, score=18.9]} {RNA1310_81495} {RNA815_42745}
50. MligTC455_19252 1355 28.24 Mlig455_054908, Mlig455_065614, Mlig455_065623

Neo: -

Age: Down-Down-Up

Region-enriched R2: 4.927/0.00706

QPCT 4.258 0.723 0.864 0.775 0.959 0.937 -

Mlig455_054908 {REF} {Length: 1427} {Pfam: Peptidase family M28 [PF04389.19, score=84.4]} {Human: ENSG00000115828, QPCT, glutaminyl-peptide cyclotransferase, [Score=113, Expect=3e-28]} {Mouse: ENSMUSG00000030407, Qpctl, glutaminyl-peptide cyclotransferase-like, [Score=123, Expect=8e-32]} {Dmel: FBgn0052412, QC, Glutaminyl cyclase, [Score=116, Expect=7e-30]} {Celegans: WBGene00010418, H27A22.1, [Score=124, Expect=6e-33]} {Smed: dd_Smed_v6_4861_0_1, dd_Smed_v6_4861_0_1, [Score=118, Expect=1e-30]} {RNA1509_35784} {RNA1310_28475}

Mlig455_065614 {REF} {Length: 1515} {Pfam: Peptidase family M28 [PF04389.19, score=121.0]} {Human: ENSG00000115828, QPCT, glutaminyl-peptide cyclotransferase, [Score=157, Expect=2e-44]} {Mouse: ENSMUSG00000024084, Qpct, glutaminyl-peptide cyclotransferase (glutaminyl cyclase), [Score=162, Expect=2e-46]; ENSMUSG00000030407, Qpctl, glutaminyl-peptide cyclotransferase-like, [Score=161, Expect=6e-46]} {Dmel: FBgn0052412, QC, Glutaminyl cyclase, [Score=158, Expect=2e-45]} {Celegans: WBGene00010418, H27A22.1, [Score=166, Expect=2e-48]} {Smed: dd_Smed_v6_4861_0_1, dd_Smed_v6_4861_0_1, [Score=156, Expect=2e-44]} {RNA1509_35784} {RNA1310_28475, RNA1509_35784}

Mlig455_065623 {REF} {Length: 1295} {Pfam: Peptidase family M28 [PF04389.19, score=121.4]} {Human: ENSG00000115828, QPCT, glutaminyl-peptide cyclotransferase, [Score=158, Expect=6e-45]} {Mouse: ENSMUSG00000030407, Qpctl, glutaminyl-peptide cyclotransferase-like, [Score=162, Expect=2e-46]; ENSMUSG00000024084, Qpct, glutaminyl-peptide cyclotransferase (glutaminyl cyclase), [Score=161, Expect=3e-46]} {Dmel: FBgn0052412, QC, Glutaminyl cyclase, [Score=154, Expect=8e-44]} {Celegans: WBGene00010418, H27A22.1, [Score=163, Expect=2e-47]} {Smed: dd_Smed_v6_4861_0_1, dd_Smed_v6_4861_0_1, [Score=154, Expect=8e-44]} {RNA1509_35784} {RNA1310_28475}
51. MligTC455_14598 52 1.07 Mlig455_058970

Neo: -

Age: -

4.24 - 0.952 0.913 0.761 0.887 0.727 Mlig455_058970 {REF} {Length: 1038} {RNA1310_39570} {RNA815_52309}
52. MligTC455_48064 23 0.48 Mlig455_061550

Neo: -

Age: -

4.233 - 0.935 0.955 0.830 0.805 0.708 Mlig455_061550 {REF} {Length: 860} {RNA1310_88363} {RNA815_47885}
53. MligTC455_49451 16 0.34 Mlig455_030374

Neo: -

Age: -

NOX5 4.23 - 0.969 0.833 0.781 0.916 0.731 Mlig455_030374 {REF} {Length: 890} {Pfam: EF hand [PF00036.34, score=93.4]; EF-hand domain [PF13405.8, score=86.0]; EF hand [PF13202.8, score=73.1]; EF-hand domain pair [PF13499.8, score=70.3]; EF-hand domain pair [PF13833.8, score=49.3]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=29.0]; EF-hand domain [PF14658.8, score=23.2]; Caleosin related protein [PF05042.15, score=20.4]; EF-hand domain [PF17958.3, score=19.8]} {Human: ENSG00000255346, NOX5, NADPH oxidase 5, [Score=67.4, Expect=2e-13]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=63.5, Expect=3e-13]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=63.2, Expect=4e-13]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=63.2, Expect=4e-13]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=63.2, Expect=4e-13]} {Dmel: FBgn0033238, azot, ahuizotl, [Score=64.3, Expect=1e-13]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=62.4, Expect=6e-13]} {Smed: dd_Smed_v6_15455_0_1, dd_Smed_v6_15455_0_1, [RH, Score=101, Expect=2e-28]} {RNA1310_74457}
54. MligTC455_43072 81 1.68 Mlig455_042521

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.590/0.02161

4.211 - 0.970 0.870 0.825 0.810 0.736 Mlig455_042521 {REF} {Length: 1049} {RNA1509_46101} {RNA1310_32444} {RNA815_30668}
55. MligTC455_14684 7049 146.85 Mlig455_051414

Neo: -

Age: -

Region-specific R2: 2.287

Region-enriched R2: 1.764/0.00001

Regeneration-depleted BL: -2.197
Regeneration-depleted TP: -1.558

PAM 4.204 - 0.776 0.774 0.798 0.890 0.966 Mlig455_051414 {REF} {Length: 1674} {TRANSSPLICED} {Pfam: NHL repeat [PF01436.23, score=89.1]} {Human: ENSG00000145730, PAM, peptidylglycine alpha-amidating monooxygenase, [RH, Score=194, Expect=4e-55]} {Mouse: ENSMUSG00000026335, Pam, peptidylglycine alpha-amidating monooxygenase, [Score=201, Expect=4e-57]} {Dmel: FBgn0262728, Pal2, Peptidyl-alpha-hydroxyglycine-alpha-amidating lyase 2, [RH, Score=206, Expect=4e-62]} {Celegans: WBGene00017671, pgal-1, Probable peptidyl-alpha-hydroxyglycine alpha-amidating lyase pgal-1, [RH, Score=206, Expect=3e-63]} {Smed: dd_Smed_v6_3093_0_1, dd_Smed_v6_3093_0_1, [RH, Score=249, Expect=2e-79]} {RNA1509_910} {RNA1310_18216.1, RNA1509_910} {RNA1509_910, RNA815_736.1}
56. MligTC455_45487 110 2.3 Mlig455_004129, Mlig455_060457

Neo: -

Age: -

4.189 0.863 0.969 - 0.729 0.904 0.724

Mlig455_004129 {REF} {Length: 1131} {Pfam: PAN domain [PF00024.28, score=18.8]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1310_37660} {RNA815_17816.1}

Mlig455_060457 {REF} {Length: 1507} {Pfam: PAN domain [PF00024.28, score=19.5]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_54623} {RNA1310_33480} {RNA815_17816.1}
57. MligTC455_16610 98 2.05 Mlig455_069894

Neo: -

Age: -

Region-enriched R2: 5.254/0.03136

WSCD2 4.174 - 0.956 0.916 0.753 0.829 0.720 Mlig455_069894 {REF} {Length: 827} {Pfam: WSC domain [PF01822.21, score=59.2]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=55.1, Expect=4e-09]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=47.8, Expect=9e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=52.4, Expect=2e-08]} {RNA1509_46267} {RNA1310_46146} {RNA815_32275.1}
58. MligTC455_23150 3195 66.56 Mlig455_009524, Mlig455_009530

Neo: -

Age: -

Region-enriched R2: 3.504/0.00000
Region-enriched R3: 1.656/0.02560

CDK16 4.12 0.718 0.963 0.778 - 0.820 0.841

Mlig455_009524 {REF} {Length: 3287} {Pfam: Protein kinase domain [PF00069.27, score=218.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.2]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [RH, Score=463, Expect=7e-159]; ENSG00000059758, CDK17, cyclin dependent kinase 17, [RH, Score=447, Expect=2e-151]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [RH, Score=464, Expect=2e-158]; ENSMUSG00000020015, Cdk17, cyclin-dependent kinase 17, [RH, Score=449, Expect=2e-152]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=362, Expect=2e-118]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [RH, Score=417, Expect=3e-138]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [RH, Score=449, Expect=6e-151]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}

Mlig455_009530 {REF} {Length: 3384} {Pfam: Protein kinase domain [PF00069.27, score=208.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [Score=432, Expect=5e-147]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [Score=431, Expect=4e-146]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=329, Expect=9e-107]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [Score=392, Expect=2e-130]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [Score=411, Expect=6e-137]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}
59. MligTC455_10966 15 0.31 Mlig455_013154

Neo: -

Age: -

4.117 - 0.973 0.781 0.718 0.932 0.713 Mlig455_013154 {REF} {Length: 827} {Pfam: Lectin C-type domain [PF00059.23, score=21.8]} {RNA1509_20946} {RNA1310_65161} {RNA815_4785.1}
60. MligTC455_20350 434 9.05 Mlig455_002780, Mlig455_066934

Neo: -

Age: -

Region-enriched R2: 3.513/0.00619

SYT12 4.083 - 0.728 0.952 0.776 0.889 0.738

Mlig455_002780 {REF} {Length: 2380} {Pfam: C2 domain [PF00168.32, score=69.7]} {Human: ENSG00000173227, SYT12, synaptotagmin 12, [Score=214, Expect=3e-64]} {Mouse: ENSMUSG00000049303, Syt12, synaptotagmin XII, [Score=207, Expect=1e-61]} {Dmel: FBgn0261085, Syt12, Synaptotagmin 12, [Score=182, Expect=3e-50]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=142, Expect=2e-37]} {Smed: dd_Smed_v6_8032_0_1, dd_Smed_v6_8032_0_1, [Score=234, Expect=3e-72]} {RNA1310_10982.1} {RNA815_10652.1}

Mlig455_066934 {REF} {Length: 2274} {Pfam: C2 domain [PF00168.32, score=69.7]} {Human: ENSG00000173227, SYT12, synaptotagmin 12, [Score=214, Expect=3e-64]} {Mouse: ENSMUSG00000049303, Syt12, synaptotagmin XII, [Score=206, Expect=1e-61]} {Dmel: FBgn0261085, Syt12, Synaptotagmin 12, [Score=182, Expect=3e-50]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=142, Expect=2e-37]} {Smed: dd_Smed_v6_8032_0_1, dd_Smed_v6_8032_0_1, [Score=234, Expect=2e-72]} {RNA1310_10982.1} {RNA815_10652.1}
61. MligTC455_20149 191 3.98 Mlig455_000246, Mlig455_058518

Neo: -

Age: -

Region-enriched R2: 4.445/0.03524

HPCAL4, NCALD 4.072 0.708 0.959 0.778 - 0.896 0.731

Mlig455_000246 {REF} {Length: 978} {Human: ENSG00000116983, HPCAL4, hippocalcin like 4, [Score=79.0, Expect=2e-17]; ENSG00000104490, NCALD, neurocalcin delta, [Score=79.0, Expect=2e-17]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=77.8, Expect=5e-17]; ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=75.5, Expect=1e-15]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=79.0, Expect=1e-17]; ENSMUSG00000046093, Hpcal4, hippocalcin-like 4, [Score=79.0, Expect=1e-17]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=77.0, Expect=7e-17]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=75.5, Expect=8e-16]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=83.2, Expect=3e-19]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=67.8, Expect=1e-13]} {Smed: dd_Smed_v6_2568_0_1, dd_Smed_v6_2568_0_1, [Score=72.0, Expect=2e-15]} {RNA1310_101382}

Mlig455_058518 {REF} {Length: 1176} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=82.0, Expect=2e-18]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=81.3, Expect=3e-18]; ENSG00000116983, HPCAL4, hippocalcin like 4, [Score=80.1, Expect=7e-18]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=82.0, Expect=8e-19]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=80.5, Expect=4e-18]; ENSMUSG00000046093, Hpcal4, hippocalcin-like 4, [Score=80.1, Expect=5e-18]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=84.0, Expect=1e-19]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=67.0, Expect=2e-13]} {Smed: dd_Smed_v6_2568_0_1, dd_Smed_v6_2568_0_1, [Score=73.2, Expect=8e-16]} {RNA1310_101382}
62. MligTC455_50348 34 0.7 Mlig455_012803

Neo: -

Age: -

4.065 0.717 0.954 0.866 0.809 - 0.719 Mlig455_012803 {REF} {Length: 488} {RNA1509_48155} {RNA1310_70969.2} {RNA815_39712}
63. MligTC455_16329 1019 21.23 Mlig455_007993

Neo: -

Age: -

Region-specific R2: 3.685

Region-enriched R2: 3.576/0.00000
Region-enriched R7: 1.704/0.00652

4.063 0.728 0.809 0.820 - 0.958 0.748 Mlig455_007993 {REF} {Length: 635} {RNA1509_22236} {RNA1310_84275, RNA1509_22236} {RNA1509_22236, RNA815_43046}
64. MligTC455_46605 388 8.08 Mlig455_032055

Neo: -

Age: -

Region-specific R2: 4.152

4.061 0.739 0.955 0.762 - 0.876 0.729 Mlig455_032055 {REF} {Length: 1416} {RNA1310_44339} {RNA815_20624}
65. MligTC455_19708 304 6.32 Mlig455_009784

Neo: -

Age: -

Region-enriched R2: 6.355/0.00039

4.017 - 0.968 0.769 0.803 0.757 0.720 Mlig455_009784 {REF} {Length: 826} {Pfam: Pancreatic hormone peptide [PF00159.20, score=43.3]} {RNA1509_54211} {RNA1310_54505.1, RNA1509_54211} {RNA1509_54211, RNA815_29389}
66. MligTC455_18139 70 1.45 Mlig455_010809

Neo: -

Age: logFC(26M/2M)=-0.809

Region-enriched R2: 6.868/0.00081

TRPC5 4.002 0.803 - 0.721 0.787 0.963 0.728 Mlig455_010809 {REF} {Length: 4442} {Pfam: Ion transport protein [PF00520.33, score=98.6]; Transient receptor ion channel II [PF08344.13, score=94.3]; Polycystin cation channel [PF08016.14, score=49.0]; Ankyrin repeats (many copies) [PF13637.8, score=37.1]; Ankyrin repeats (3 copies) [PF12796.9, score=33.2]; Ankyrin repeat [PF13606.8, score=25.4]; Ankyrin repeats (many copies) [PF13857.8, score=24.1]; Ankyrin repeat [PF00023.32, score=23.2]} {Human: ENSG00000072315, TRPC5, transient receptor potential cation channel subfamily C member 5, [RH, Score=743, Expect=0.0]; ENSG00000133107, TRPC4, transient receptor potential cation channel subfamily C member 4, [RH, Score=740, Expect=0.0]} {Mouse: ENSMUSG00000041710, Trpc5, transient receptor potential cation channel, subfamily C, member 5, [RH, Score=744, Expect=0.0]; ENSMUSG00000027748, Trpc4, transient receptor potential cation channel, subfamily C, member 4, [RH, Score=740, Expect=0.0]} {Dmel: FBgn0032593, Trpgamma, Transient receptor potential cation channel gamma, [RH, Score=848, Expect=0.0]} {Celegans: WBGene00006615, trp-2, TRP (Transient receptor potential) channel family; TRP homlogous cation channel protein, [RH, Score=694, Expect=0.0]} {Smed: dd_Smed_v6_20495_0_1, dd_Smed_v6_20495_0_1, [RH, Score=1017, Expect=0.0]} {RNA1509_34138} {RNA1310_12839, RNA1509_34138} {RNA1509_34138, RNA815_17637}
67. MligTC455_26766 638 13.3 Mlig455_017977

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.360

Region-enriched R2: 3.395/0.00052

3.946 - 0.702 0.961 0.771 0.759 0.753 Mlig455_017977 {REF} {Length: 2516} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [Score=249, Expect=3e-71]} {RNA1509_19813} {RNA1310_621} {RNA815_183.1}
68. MligTC455_43390 28 0.59 Mlig455_064273

Neo: -

Age: Down-Up-Down

PRKAR2A 3.662 0.863 0.953 0.936 - 0.910 - Mlig455_064273 {REF} {Length: 2394} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=122.5]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=40.5]} {Human: ENSG00000114302, PRKAR2A, protein kinase cAMP-dependent type II regulatory subunit alpha, [Score=305, Expect=2e-100]; ENSG00000005249, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, [Score=296, Expect=8e-97]; ENSG00000284096, PRKAR2B, protein kinase cAMP-dependent type II regulatory subunit beta, [Score=296, Expect=8e-97]} {Mouse: ENSMUSG00000032601, Prkar2a, protein kinase, cAMP dependent regulatory, type II alpha, [Score=314, Expect=6e-104]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [Score=335, Expect=1e-112]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=219, Expect=2e-68]} {Smed: dd_Smed_v6_4188_0_1, dd_Smed_v6_4188_0_1, [Score=335, Expect=5e-113]} {RNA1509_34470} {RNA1310_27777} {RNA815_5628}
69. MligTC455_48656 24 0.5 Mlig455_039647

Neo: -

Age: -

3.626 - 0.969 0.926 0.805 0.926 - Mlig455_039647 {REF} {Length: 1715} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=42.7]} {RNA1310_48037} {RNA815_27969}
70. MligTC455_48518 1365 28.44 Mlig455_004430, Mlig455_004445

Neo: -

Age: -

Region-enriched R6: 4.827/0.00024
Region-enriched R2: 4.789/0.00134
Region-enriched R7: 3.445/0.01502

3.596 - 0.924 0.897 0.816 0.959 -

Mlig455_004430 {REF} {Length: 3275} {Pfam: GDNF/GAS1 domain [PF02351.18, score=23.6]} {Smed: dd_Smed_v6_19517_0_1, dd_Smed_v6_19517_0_1, [RH, Score=113, Expect=2e-25]} {RNA1509_50708} {RNA1310_13399, RNA1509_50708} {RNA1509_50708, RNA815_36630}

Mlig455_004445 {REF} {Length: 796} {RNA1509_12695} {RNA1310_66704} {RNA815_33428}
71. MligTC455_48517 682 14.21 Mlig455_004431

Neo: -

Age: -

Region-enriched R6: 4.694/0.00066
Region-enriched R2: 4.683/0.00294

3.593 - 0.924 0.895 0.816 0.958 - Mlig455_004431 {REF} {Length: 3101} {Smed: dd_Smed_v6_19517_0_1, dd_Smed_v6_19517_0_1, [RH, Score=112, Expect=3e-25]} {RNA1509_50708} {RNA1310_13399} {RNA815_33428}
72. MligTC455_16974 15 0.32 Mlig455_052824

Neo: -

Age: -

3.589 0.855 0.969 - 0.833 0.932 - Mlig455_052824 {REF} {Length: 306} {NoTransDecoderORF} {RNA1310_65069} {RNA815_35708.2}
73. MligTC455_39544 611 12.73 Mlig455_001809, Mlig455_001836, Mlig455_062227, Mlig455_062236

Neo: -

Age: -

Region-specific R2: 8.576

Region-enriched R2: 8.112/0.00016

3.588 0.835 0.968 0.951 0.834 - -

Mlig455_001809 {REF} {Length: 1067} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}

Mlig455_001836 {REF} {Length: 1065} {RNA1509_52939} {RNA1310_72581, RNA1509_52939} {RNA1509_52939, RNA815_24546}

Mlig455_062227 {REF} {Length: 3520} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}

Mlig455_062236 {REF} {Length: 620} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}
74. MligTC455_39495 30 0.62 Mlig455_037087

Neo: -

Age: -

3.579 - 0.969 0.815 0.831 0.964 - Mlig455_037087 {REF} {Length: 1984} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=38.4]} {Dmel: FBgn0035385, FMRFaR, FMRFamide Receptor, [Score=49.7, Expect=2e-06]} {RNA1310_19222} {RNA815_35367}
75. MligTC455_40290 58 1.21 Mlig455_058728

Neo: -

Age: -

Region-enriched R2: 4.464/0.00807
Region-enriched R7: 3.833/0.03206

3.549 0.851 0.952 0.927 - 0.819 - Mlig455_058728 {REF} {Length: 1351} {Pfam: CUB domain [PF00431.22, score=48.4]} {RNA1310_48745} {RNA815_23305}
76. MligTC455_39988 83 1.73 Mlig455_062081

Neo: -

Age: -

3.541 0.877 0.975 0.957 - - 0.732 Mlig455_062081 {REF} {Length: 447} {NoTransDecoderORF} {RNA1509_50426} {RNA1310_88257} {RNA815_17173.4}
77. MligTC455_50053 284 5.92 Mlig455_030746

Neo: -

Age: -

Region-enriched R2: 1.768/0.02980

STOM 3.537 0.903 - 0.908 - 0.951 0.775 Mlig455_030746 {REF} {Length: 2635} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=58.5]} {Human: ENSG00000148175, STOM, stomatin, [Score=257, Expect=7e-85]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=253, Expect=2e-83]} {Dmel: FBgn0260657, CG42540, [Score=262, Expect=9e-86]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=275, Expect=6e-91]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=304, Expect=4e-104]} {RNA1509_53478} {RNA1310_8094.2} {RNA815_8739}
78. MligTC455_50594 440 9.18 Mlig455_010362

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.701

Region-enriched R2: 4.104/0.00000

3.526 - 0.973 - 0.784 0.931 0.838 Mlig455_010362 {REF} {Length: 685} {RNA1509_30018} {RNA1310_56512.2} {RNA815_28562}
79. MligTC455_22263 1046 21.79 Mlig455_034483

Neo: -

Age: -

Region-specific R2: 3.299

Region-enriched R2: 2.796/0.00007

3.514 - 0.871 0.707 0.991 0.945 - Mlig455_034483 {REF} {Length: 740} {Smed: dd_Smed_v6_4417_0_1, dd_Smed_v6_4417_0_1, [Score=40.8, Expect=1e-05]} {RNA1509_19386, RNA1509_37949} {RNA1310_48041.1, RNA1509_37949} {RNA1509_37949, RNA815_28750}
80. MligTC455_38950 23 0.47 Mlig455_065213

Neo: -

Age: -

3.506 0.863 0.972 0.940 - - 0.731 Mlig455_065213 {REF} {Length: 567} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=23.2]} {RNA1509_44618} {RNA1310_63839} {RNA815_35329}
81. MligTC455_10299 72 1.51 Mlig455_023028, Mlig455_023125, Mlig455_023183

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.617

Region-enriched R2: 4.572/0.04281

ANGPTL1 3.501 0.876 0.972 0.885 0.768 - -

Mlig455_023028 {REF} {Length: 2538} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=130.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=115, Expect=8e-29]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=112, Expect=1e-27]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=114, Expect=2e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=112, Expect=9e-28]} {Dmel: FBgn0050280, CG30280, [Score=103, Expect=9e-26]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=50.8, Expect=4e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}

Mlig455_023125 {REF} {Length: 2398} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=127.5]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=112, Expect=2e-27]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=107, Expect=1e-25]} {Mouse: ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=107, Expect=7e-26]} {Dmel: FBgn0050280, CG30280, [Score=92.8, Expect=6e-22]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=51.2, Expect=3e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}

Mlig455_023183 {REF} {Length: 2190} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=129.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=115, Expect=2e-28]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=110, Expect=9e-27]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=113, Expect=4e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=110, Expect=6e-27]} {Dmel: FBgn0003326, sca, scabrous, [Score=104, Expect=8e-25]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=50.4, Expect=4e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}
82. MligTC455_22077 58 1.2 Mlig455_041277

Neo: -

Age: -

3.499 - 0.969 0.813 0.828 0.889 - Mlig455_041277 {REF} {Length: 1351} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=30.4]} {RNA1310_27422} {RNA815_33833}
83. MligTC455_40781 153 3.2 Mlig455_024109, Mlig455_063982

Neo: -

Age: -

3.494 - 0.886 0.845 0.792 0.971 -

Mlig455_024109 {REF} {Length: 1081} {RNA1509_16458} {RNA1310_43664.1, RNA1509_16458} {RNA1509_16458, RNA815_23166}

Mlig455_063982 {REF} {Length: 3562} {RNA1509_16458} {RNA1310_30070} {RNA815_23166}
84. MligTC455_19709 221 4.6 Mlig455_010385

Neo: -

Age: -

Region-enriched R2: 4.689/0.03280

3.488 0.863 0.970 - 0.827 - 0.828 Mlig455_010385 {REF} {Length: 903} {Pfam: Pancreatic hormone peptide [PF00159.20, score=43.2]} {RNA1509_54211} {RNA1310_54505.2} {RNA815_29389}
85. MligTC455_46067 548 11.42 Mlig455_054518, Mlig455_055436, Mlig455_055448

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.305/0.04262

GRIK3, GRIK4 3.488 0.830 0.974 - - 0.920 0.764

Mlig455_054518 {REF} {Length: 4725} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=91.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.2]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=222, Expect=5e-60]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=222, Expect=6e-60]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=218, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=3e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=215, Expect=1e-57]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=9e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=213, Expect=9e-57]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=224, Expect=2e-60]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=224, Expect=9e-61]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=220, Expect=2e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=215, Expect=1e-57]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=296, Expect=6e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=312, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_14215, RNA1509_40992} {RNA1310_5620.1, RNA1509_14215, RNA1509_40992} {RNA1509_14215, RNA1509_40992, RNA815_1965}

Mlig455_055436 {REF} {Length: 4732} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=6e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=7e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=7e-59]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=9e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=211, Expect=2e-56]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=226, Expect=3e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_40992} {RNA1310_5620.1} {RNA815_1965}

Mlig455_055448 {REF} {Length: 4726} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=9e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=9e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=8e-59]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=217, Expect=2e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=7e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=6e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=225, Expect=4e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=217, Expect=9e-59]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=5e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_32892, RNA1509_40992} {RNA1310_5620.1, RNA1509_32892} {RNA1509_32892, RNA815_1965}
86. MligTC455_19775 36 0.74 Mlig455_060359

Neo: -

Age: -

FCN1 3.484 0.863 0.969 0.825 - - 0.827 Mlig455_060359 {REF} {Length: 1109} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=120.9]} {Human: ENSG00000085265, FCN1, ficolin 1, [Score=99.0, Expect=2e-23]; ENSG00000142748, FCN3, ficolin 3, [Score=99.0, Expect=1e-23]; ENSG00000160339, FCN2, ficolin 2, [Score=98.2, Expect=2e-23]} {Mouse: ENSMUSG00000026938, Fcna, ficolin A, [Score=100, Expect=3e-24]} {Dmel: FBgn0034160, CG5550, [Score=97.8, Expect=7e-24]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=90.1, Expect=4e-20]} {RNA1310_67383} {RNA815_45536}
87. MligTC455_10899 46 0.95 Mlig455_013784, Mlig455_013915

Neo: -

Age: -

3.479 - 0.968 0.911 0.772 0.828 -

Mlig455_013784 {REF} {Length: 1362} {Pfam: Glycine rich protein [PF12810.9, score=20.8]} {RNA1509_28715} {RNA1310_91773} {RNA815_35307}

Mlig455_013915 {REF} {Length: 1516} {Pfam: Glycine rich protein [PF12810.9, score=20.3]} {RNA1509_28715} {RNA1310_91773} {RNA815_35307}
88. MligTC455_40119 114 2.37 Mlig455_034596

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.158/0.00258

KCNIP1 3.478 - 0.968 0.914 - 0.892 0.704 Mlig455_034596 {REF} {Length: 1987} {Pfam: EF-hand domain pair [PF13499.8, score=42.4]; EF hand [PF00036.34, score=38.6]; EF-hand domain [PF13405.8, score=33.5]; EF hand [PF13202.8, score=31.2]; EF-hand domain pair [PF13833.8, score=28.7]} {Human: ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=122, Expect=3e-32]; ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=122, Expect=2e-32]; ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=119, Expect=1e-30]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=124, Expect=5e-33]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=122, Expect=1e-32]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=100, Expect=6e-25]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=103, Expect=6e-26]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=122, Expect=7e-33]} {RNA1310_43225} {RNA815_33406}
89. MligTC455_16526 125 2.61 Mlig455_026747, Mlig455_051738, Mlig455_051739, Mlig455_051760

Neo: -

Age: Up-Down-Down

GABRG3 3.475 - 0.890 0.826 - 0.950 0.809

Mlig455_026747 {REF} {Length: 6317} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=31.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=25.1]} {Human: ENSG00000182256, GABRG3, gamma-aminobutyric acid type A receptor gamma3 subunit, [Score=57.8, Expect=4e-08]; ENSG00000113327, GABRG2, gamma-aminobutyric acid type A receptor gamma2 subunit, [Score=57.4, Expect=5e-08]} {Mouse: ENSMUSG00000055026, Gabrg3, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3, [Score=60.8, Expect=3e-09]} {Celegans: WBGene00001512, gab-1, Gamma-aminobutyric acid receptor subunit beta, [Score=49.3, Expect=7e-06]} {Smed: dd_Smed_v6_10171_0_1, dd_Smed_v6_10171_0_1, [Score=517, Expect=2e-177]} {RNA1310_24908.1} {RNA815_12627}

Mlig455_051738 {REF} {Length: 1364} {RNA1310_43175} {RNA815_39065}

Mlig455_051739 {REF} {Length: 2058} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=32.3]} {Human: ENSG00000182256, GABRG3, gamma-aminobutyric acid type A receptor gamma3 subunit, [Score=58.9, Expect=1e-08]} {Mouse: ENSMUSG00000055026, Gabrg3, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3, [Score=62.8, Expect=5e-10]} {Smed: dd_Smed_v6_10171_0_1, dd_Smed_v6_10171_0_1, [Score=532, Expect=0.0]} {RNA1310_16047} {RNA815_12627}

Mlig455_051760 {REF} {Length: 5962} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=32.2]} {Human: ENSG00000182256, GABRG3, gamma-aminobutyric acid type A receptor gamma3 subunit, [Score=72.8, Expect=5e-13]; ENSG00000113327, GABRG2, gamma-aminobutyric acid type A receptor gamma2 subunit, [Score=69.7, Expect=5e-12]} {Mouse: ENSMUSG00000055026, Gabrg3, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3, [Score=77.0, Expect=2e-14]} {Dmel: FBgn0030707, CG8916, [Score=60.5, Expect=2e-09]} {Celegans: WBGene00001512, gab-1, Gamma-aminobutyric acid receptor subunit beta, [Score=57.8, Expect=1e-08]} {Smed: dd_Smed_v6_10171_0_1, dd_Smed_v6_10171_0_1, [RH, Score=573, Expect=0.0]} {RNA1310_24908.1} {RNA815_12627}
90. MligTC455_47875 72 1.5 Mlig455_067941

Neo: -

Age: -

3.464 0.808 0.976 0.863 - - 0.817 Mlig455_067941 {REF} {Length: 1399} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.8, Expect=7e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
91. MligTC455_18607 203 4.23 Mlig455_012344, Mlig455_012722

Neo: -

Age: -

Region-enriched R2: 3.338/0.02204

ANKRD63 3.461 - 0.959 0.890 0.748 0.864 -

Mlig455_012344 {REF} {Length: 1989} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=77.3]; Ankyrin repeats (many copies) [PF13637.8, score=67.3]; Ankyrin repeat [PF00023.32, score=56.6]; Ankyrin repeats (many copies) [PF13857.8, score=50.3]; Ankyrin repeat [PF13606.8, score=47.6]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=55.5, Expect=5e-08]} {Celegans: WBGene00006882, vab-19, VAB-19, [Score=52.0, Expect=5e-07]} {Smed: dd_Smed_v6_11187_0_1, dd_Smed_v6_11187_0_1, [Score=59.3, Expect=2e-09]} {RNA1310_37830} {RNA815_38436}

Mlig455_012722 {REF} {Length: 2256} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=77.2]; Ankyrin repeats (many copies) [PF13637.8, score=67.3]; Ankyrin repeat [PF00023.32, score=56.6]; Ankyrin repeats (many copies) [PF13857.8, score=50.3]; Ankyrin repeat [PF13606.8, score=47.6]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [RH, Score=129, Expect=1e-33]} {Dmel: FBgn0031473, CG3104, [Score=54.7, Expect=5e-08]} {Celegans: WBGene00006882, vab-19, VAB-19, [Score=52.0, Expect=5e-07]} {Smed: dd_Smed_v6_11187_0_2, dd_Smed_v6_11187_0_2, [Score=59.7, Expect=1e-09]} {RNA1310_37830} {RNA815_38436}
92. MligTC455_43140 1841 38.34 Mlig455_031799, Mlig455_047599

Neo: -

Age: -

Region-enriched R8: 3.365/0.00001
Region-enriched R2: 2.285/0.02720

GNAS 3.452 - 0.791 - 0.773 0.935 0.953

Mlig455_031799 {REF} {Length: 1853} {Pfam: G-protein alpha subunit [PF00503.22, score=342.0]; ADP-ribosylation factor family [PF00025.23, score=58.4]; Gtr1/RagA G protein conserved region [PF04670.14, score=24.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=19.9]} {Human: ENSG00000087460, GNAS, GNAS complex locus, [RH, Score=514, Expect=0.0]; ENSG00000141404, GNAL, G protein subunit alpha L, [RH, Score=506, Expect=1e-179]} {Mouse: ENSMUSG00000027523, Gnas, GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, [RH, Score=512, Expect=0.0]; ENSMUSG00000024524, Gnal, guanine nucleotide binding protein, alpha stimulating, olfactory type, [RH, Score=510, Expect=0.0]} {Dmel: FBgn0001123, Galphas, G protein alpha s subunit, [RH, Score=511, Expect=0.0]} {Celegans: WBGene00001745, gsa-1, G protein, Subunit Alpha, [RH, Score=469, Expect=2e-165]} {Smed: dd_Smed_v6_6167_0_1, dd_Smed_v6_6167_0_1, [RH, Score=540, Expect=0.0]} {RNA1509_55942} {RNA1310_13501} {RNA815_7904}

Mlig455_047599 {REF} {Length: 1095} {RNA1509_25915, RNA1509_33730} {RNA1310_45973, RNA1509_25915, RNA1509_33730} {RNA1509_25915, RNA1509_33730, RNA815_22813}
93. MligTC455_11765 292 6.08 Mlig455_032580, Mlig455_032642

Neo: -

Age: -

Region-specific R2: 6.434

Region-enriched R2: 4.662/0.03055

3.451 0.822 0.971 - 0.825 0.833 -

Mlig455_032580 {REF} {Length: 565} {RNA1509_42630} {RNA1310_64208} {RNA815_32993}

Mlig455_032642 {REF} {Length: 663} {RNA1509_42630} {RNA1310_64208} {RNA815_32993}
94. MligTC455_28693 60 1.26 Mlig455_022354

Neo: -

Age: -

3.445 - 0.971 0.936 - 0.820 0.718 Mlig455_022354 {REF} {Length: 816} {Pfam: WSC domain [PF01822.21, score=53.0]; PAN domain [PF00024.28, score=20.6]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=48.1, Expect=2e-06]} {RNA1509_43359} {RNA1310_59466.1} {RNA815_19988}
95. MligTC455_19616 70 1.46 Mlig455_045100

Neo: -

Age: -

RPH3A 3.428 0.872 - 0.953 0.729 0.874 - Mlig455_045100 {REF} {Length: 2276} {Pfam: C2 domain [PF00168.32, score=141.3]} {Human: ENSG00000089169, RPH3A, rabphilin 3A, [RH, Score=247, Expect=9e-73]} {Mouse: ENSMUSG00000029608, Rph3a, rabphilin 3A, [RH, Score=244, Expect=9e-72]} {Dmel: FBgn0030230, Rph, Rabphilin, [Score=179, Expect=2e-50]} {Celegans: WBGene00004316, rbf-1, Rabphilin-1, [Score=209, Expect=6e-58]} {Smed: dd_Smed_v6_12977_0_1, dd_Smed_v6_12977_0_1, [Score=216, Expect=3e-62]} {RNA1310_30378} {RNA815_36857}
96. MligTC455_46708 362 7.53 Mlig455_045334

Neo: -

Age: -

Region-enriched R2: 2.783/0.01800

3.427 0.875 0.793 0.950 - - 0.809 Mlig455_045334 {REF} {Length: 1243} {RNA1509_51601} {RNA1310_43115.2, RNA1509_51601} {RNA1509_51601, RNA815_21402.1}
97. MligTC455_25599 311 6.48 Mlig455_049324

Neo: -

Age: -

Region-enriched R2: 3.470/0.00001

3.424 0.877 0.950 - 0.809 0.788 - Mlig455_049324 {REF} {Length: 968} {RNA1509_38952} {RNA1310_62775} {RNA815_32364}
98. MligTC455_47874 67 1.4 Mlig455_000340

Neo: -

Age: -

3.419 0.808 0.976 0.834 - - 0.801 Mlig455_000340 {REF} {Length: 1412} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.4, Expect=9e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
99. MligTC455_17562 108 2.25 Mlig455_022496

Neo: -

Age: -

NECAB3 3.414 - - 0.954 0.745 0.859 0.856 Mlig455_022496 {REF} {Length: 1499} {Pfam: EF hand [PF00036.34, score=34.0]; EF-hand domain [PF13405.8, score=33.4]; EF-hand domain pair [PF13833.8, score=29.2]; EF-hand domain pair [PF13499.8, score=28.3]; Antibiotic biosynthesis monooxygenase [PF03992.18, score=22.0]; EF hand [PF13202.8, score=21.3]} {Human: ENSG00000125967, NECAB3, N-terminal EF-hand calcium binding protein 3, [RH, Score=189, Expect=7e-57]; ENSG00000123119, NECAB1, N-terminal EF-hand calcium binding protein 1, [RH, Score=186, Expect=1e-55]} {Mouse: ENSMUSG00000040536, Necab1, N-terminal EF-hand calcium binding protein 1, [RH, Score=191, Expect=7e-58]; ENSMUSG00000027489, Necab3, N-terminal EF-hand calcium binding protein 3, [RH, Score=191, Expect=9e-58]} {RNA1509_46831} {RNA1310_24461} {RNA815_25216}
100. MligTC455_45496 144 2.99 Mlig455_010048

Neo: -

Age: Up-Down-Up

Region-enriched R2: 3.720/0.00332

CAV2 3.413 0.893 0.969 0.804 - - 0.747 Mlig455_010048 {REF} {Length: 2607} {Pfam: Caveolin [PF01146.19, score=125.0]} {Human: ENSG00000105971, CAV2, caveolin 2, [Score=85.5, Expect=3e-21]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [Score=89.4, Expect=7e-23]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=79.0, Expect=2e-18]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=153, Expect=1e-48]} {RNA1509_20287} {RNA1310_50581.1, RNA1509_20287} {RNA1509_20287, RNA815_31873}

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