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Results for MligTC455_38162

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_38162 710 14.80 Mlig455_045004

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.269

Region-enriched R2: 5.838/0.00000

Regeneration-downregulated R2: -4.412

Regeneration-depleted R2: -4.412

Mlig455_045004 {REF} {Length: 659} {Smed: dd_Smed_v6_4046_0_1, dd_Smed_v6_4046_0_1, [Score=57.8, Expect=2e-12]} {RNA1509_50998, RNA1509_57106} {RNA1310_56015, RNA1509_50998, RNA1509_57106} {RNA1509_50998, RNA1509_57106, RNA815_29915}

Cumulative graph for MligTC455_38162

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.933 4.122 0.56694 1.00000
RegionR2 5.838 4.122 0.00000 0.00000 Specific for R2: 5.269
RegionR3 -0.844 4.122 0.39647 0.92626
RegionR4 0.73 4.122 0.51178 0.83795
RegionR5 0.307 4.122 0.72028 1.00000
RegionR6 -3.071 4.122 0.01918 0.24860
RegionR7 -1.349 4.122 0.37444 1.00000
RegionR8 -0.679 4.122 0.73507 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.379 4.122 0.90218 1.00000
RegenerationR2 -4.412 4.122 0.00001 0.00343 Specific for R2: -4.412
RegenerationR3 -3.431 4.122 0.00322 0.10074
RegenerationR4 -2.766 4.122 0.01414 0.18589
RegenerationR5 -4.211 4.122 0.00043 0.03323
RegenerationR6 0.053 4.122 0.90639 1.00000
RegenerationBL -0.516 4.122 0.70924 1.00000
RegenerationTP -0.914 4.122 0.51490 0.91096


Genes with expression patterns similar to MligTC455_38162

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_38162 710 14.8 Mlig455_045004

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.269

Region-enriched R2: 5.838/0.00000

Regeneration-downregulated R2: -4.412

Regeneration-depleted R2: -4.412

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_045004 {REF} {Length: 659} {Smed: dd_Smed_v6_4046_0_1, dd_Smed_v6_4046_0_1, [Score=57.8, Expect=2e-12]} {RNA1509_50998, RNA1509_57106} {RNA1310_56015, RNA1509_50998, RNA1509_57106} {RNA1509_50998, RNA1509_57106, RNA815_29915}
2. MligTC455_17178 54 1.12 Mlig455_067758

Neo: -

Age: -

Region-enriched R2: 7.471/0.00007

5.816 0.958 0.950 0.970 0.968 0.979 0.991 Mlig455_067758 {REF} {Length: 2301} {RNA1509_44702} {RNA1310_14743} {RNA815_20669.1}
3. MligTC455_38949 105 2.19 Mlig455_065209

Neo: -

Age: -

Region-specific R2: 7.633

Region-enriched R2: 10.088/0.00000

5.812 0.959 0.985 0.962 0.969 0.940 0.997 Mlig455_065209 {REF} {Length: 591} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=23.2]} {RNA1509_44618} {RNA1310_63839, RNA1509_44618} {RNA1509_44618, RNA815_35329}
4. MligTC455_17177 103 2.15 Mlig455_048992, Mlig455_049009

Neo: -

Age: Down-Down-Up

5.803 0.960 0.969 0.958 0.961 0.958 0.997

Mlig455_048992 {REF} {Length: 1836} {RNA1509_44702} {RNA1310_14743, RNA1509_44702} {RNA1509_44702, RNA815_20669.1}

Mlig455_049009 {REF} {Length: 1823} {RNA1509_44702} {RNA1310_14743} {RNA815_20669.1}
5. MligTC455_47420 218 4.54 Mlig455_017159, Mlig455_048110

Neo: -

Age: -

Region-specific R2: 6.469

Region-enriched R2: 5.851/0.00135

5.79 0.971 0.972 0.961 0.960 0.982 0.944

Mlig455_017159 {REF} {Length: 1062} {RNA1509_35349} {RNA1310_81586}

Mlig455_048110 {REF} {Length: 527} {RNA1310_81586}
6. MligTC455_44525 3358 69.96 Mlig455_004678, Mlig455_004741, Mlig455_004755, Mlig455_004840

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.742

Region-enriched R2: 10.296/0.00000
Region-enriched R3: 3.568/0.01807

5.754 0.920 0.983 0.957 0.989 0.912 0.993

Mlig455_004678 {REF} {Length: 845} {RNA1509_25712} {RNA1310_68954.2} {RNA815_35323}

Mlig455_004741 {REF} {Length: 961} {RNA1509_25712} {RNA1310_68954.1} {RNA815_35323}

Mlig455_004755 {REF} {Length: 1059} {RNA1509_25712} {RNA1310_68954.2} {RNA815_35323}

Mlig455_004840 {REF} {Length: 918} {RNA1509_25712, RNA1509_29691} {RNA1310_68954.2, RNA1509_25712, RNA1509_29691} {RNA1509_25712, RNA1509_29691, RNA815_35323}
7. MligTC455_52629 472 9.83 Mlig455_059435

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.775

Region-enriched R2: 6.727/0.00002

5.738 0.908 0.983 0.889 0.969 0.992 0.997 Mlig455_059435 {REF} {Length: 726} {RNA1509_48505} {RNA1310_62885} {RNA815_39881}
8. MligTC455_51334 326 6.78 Mlig455_011442, Mlig455_061180

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.828

5.712 0.902 0.901 0.955 0.969 0.986 0.999

Mlig455_011442 {REF} {Length: 742} {RNA1310_57576.1} {RNA815_29867}

Mlig455_061180 {REF} {Length: 769} {RNA1310_57576.1} {RNA815_29867}
9. MligTC455_19552 288 6 Mlig455_055936, Mlig455_068188

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.424

Region-specific R2: 6.302

Region-enriched R2: 4.919/0.00633

Regeneration-depleted R4: -5.607
Regeneration-depleted R2: -3.270

5.673 0.861 0.984 0.901 0.963 0.982 0.982

Mlig455_055936 {REF} {Length: 665} {RNA1310_71052} {RNA815_36745}

Mlig455_068188 {REF} {Length: 714} {RNA1310_71052} {RNA815_36745}
10. MligTC455_50455 972 20.25 Mlig455_070346

Neo: -

Age: -

Region-specific R2: 4.855

Region-enriched R2: 5.186/0.00000

5.638 0.716 0.998 0.963 0.998 0.968 0.995 Mlig455_070346 {REF} {Length: 932} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=34.4]; Nematode insulin-related peptide beta type [PF03488.16, score=21.4]} {RNA1509_18514, RNA1509_58074} {RNA1310_51990, RNA1509_18514, RNA1509_58074} {RNA1509_18514, RNA1509_58074, RNA815_25071}
11. MligTC455_50694 602 12.54 Mlig455_058794, Mlig455_070066

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.478

Region-enriched R2: 3.805/0.01454

5.637 0.895 0.841 0.969 0.967 0.972 0.993

Mlig455_058794 {REF} {Length: 776} {RNA1310_76208} {RNA815_49041}

Mlig455_070066 {REF} {Length: 781} {RNA1310_76208} {RNA815_49041}
12. MligTC455_17578 447 9.32 Mlig455_010738

Neo: -

Age: Down-Up-Up

Region-specific R2: 8.320

Region-enriched R2: 9.793/0.00000

5.595 0.853 0.992 0.813 0.970 0.971 0.996 Mlig455_010738 {REF} {Length: 642} {RNA1509_48297, RNA1509_55742} {RNA1310_84623, RNA1509_48297, RNA1509_55742} {RNA1509_48297, RNA1509_55742, RNA815_45356}
13. MligTC455_49919 745 15.52 Mlig455_017182, Mlig455_048150

Neo: -

Age: -

Region-specific R2: 7.180

Region-enriched R2: 7.978/0.00000

Regeneration-downregulated R2: -4.649

Regeneration-depleted R2: -4.649

5.574 0.906 0.729 0.986 0.965 0.990 0.998

Mlig455_017182 {REF} {Length: 576} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1310_60849, RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1509_35830, RNA1509_49816, RNA1509_53987, RNA815_31347}

Mlig455_048150 {REF} {Length: 574} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830} {RNA1310_60849} {RNA815_31347}
14. MligTC455_12512 80 1.68 Mlig455_017689

Neo: -

Age: -

5.563 0.960 0.982 0.791 0.860 0.977 0.993 Mlig455_017689 {REF} {Length: 934} {RNA1310_37507} {RNA815_32171}
15. MligTC455_43602 1418 29.54 Mlig455_053986

Neo: -

Age: -

Region-specific R2: 4.626

Region-enriched R2: 3.844/0.00000

Regeneration-downregulated R2: -2.432

Regeneration-depleted R2: -2.432

5.562 0.904 0.871 0.942 0.964 0.943 0.938 Mlig455_053986 {REF} {Length: 2161} {RNA1509_15576} {RNA1310_12096.1} {RNA815_32931}
16. MligTC455_16358 1175 24.47 Mlig455_039878

Neo: -

Age: -

Region-specific R2: 4.659

Region-enriched R2: 4.310/0.00000

5.552 0.988 0.936 0.932 0.942 0.976 0.778 Mlig455_039878 {REF} {Length: 1188} {RNA1509_60020} {RNA1310_35099.1, RNA1509_60020} {RNA1509_60020, RNA815_1356.1}
17. MligTC455_29119 68 1.42 Mlig455_050458

Neo: -

Age: -

Region-enriched R2: 5.525/0.01281

5.522 0.955 0.980 0.843 0.927 0.938 0.879 Mlig455_050458 {REF} {Length: 624} {RNA1509_53840} {RNA1310_67192} {RNA815_27042}
18. MligTC455_48756 622 12.96 Mlig455_054772, Mlig455_054799, Mlig455_054893

Neo: -

Age: -

Region-specific R2: 7.873

Region-enriched R2: 9.003/0.00000

5.522 0.925 0.756 0.959 0.956 0.928 0.998

Mlig455_054772 {REF} {Length: 716} {RNA1509_41507} {RNA1310_49516} {RNA815_28703}

Mlig455_054799 {REF} {Length: 625} {RNA1509_41507} {RNA1310_49516} {RNA815_28703}

Mlig455_054893 {REF} {Length: 947} {RNA1509_41507} {RNA1310_49516, RNA1509_41507} {RNA1509_41507, RNA815_28703}
19. MligTC455_46430 62 1.29 Mlig455_057117, Mlig455_069301

Neo: -

Age: -

GUCY2F 5.482 0.904 0.741 0.916 0.958 0.968 0.995

Mlig455_057117 {REF} {Length: 2651} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=196.0]; Nitrate and nitrite sensing [PF08376.12, score=82.5]; Heme NO binding associated [PF07701.16, score=28.2]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=247, Expect=9e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=242, Expect=3e-68]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=238, Expect=5e-67]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=246, Expect=7e-70]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=242, Expect=2e-68]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=241, Expect=7e-68]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=239, Expect=3e-67]} {Dmel: FBgn0053958, CG33958, [Score=266, Expect=4e-79]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=235, Expect=3e-66]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=238, Expect=4e-67]} {RNA1509_38781} {RNA1310_35456} {RNA815_22108}

Mlig455_069301 {REF} {Length: 2370} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=178.1]; Nitrate and nitrite sensing [PF08376.12, score=82.3]; Heme NO binding associated [PF07701.16, score=28.0]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=232, Expect=2e-64]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=232, Expect=1e-64]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=225, Expect=5e-62]} {Dmel: FBgn0053958, CG33958, [Score=250, Expect=5e-73]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=223, Expect=1e-61]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=221, Expect=4e-61]} {RNA1509_38781} {RNA1310_35456} {RNA815_24181}
20. MligTC455_17299 538 11.21 Mlig455_036559, Mlig455_057787

Neo: -

Age: -

Region-enriched R2: 5.046/0.00000
Region-enriched R3: 3.527/0.00004

5.439 0.798 0.957 0.884 0.875 0.934 0.991

Mlig455_036559 {REF} {Length: 718} {RNA1509_57277} {RNA1310_52579, RNA1509_57277} {RNA1509_57277, RNA815_26706}

Mlig455_057787 {REF} {Length: 741} {RNA1509_57277} {RNA1310_52579} {RNA815_26706}
21. MligTC455_45350 92 1.93 Mlig455_024760, Mlig455_058317, Mlig455_068656

Neo: -

Age: Up-Down-Down

SLC17A6, SLC17A8 5.423 0.868 0.815 0.959 0.932 0.856 0.993

Mlig455_024760 {REF} {Length: 2935} {Pfam: Major Facilitator Superfamily [PF07690.18, score=158.2]} {Human: ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=522, Expect=5e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=530, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=527, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=487, Expect=1e-165]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=474, Expect=3e-161]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=583, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}

Mlig455_058317 {REF} {Length: 2971} {Pfam: Major Facilitator Superfamily [PF07690.18, score=157.7]} {Human: ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=534, Expect=0.0]; ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=521, Expect=8e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=531, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=526, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=485, Expect=1e-164]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [Score=474, Expect=7e-162]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [Score=585, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}

Mlig455_068656 {REF} {Length: 3034} {Pfam: Major Facilitator Superfamily [PF07690.18, score=158.2]} {Human: ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [RH, Score=531, Expect=0.0]; ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [RH, Score=531, Expect=0.0]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [RH, Score=522, Expect=5e-180]} {Mouse: ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [RH, Score=536, Expect=0.0]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [RH, Score=530, Expect=0.0]; ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [RH, Score=527, Expect=0.0]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=487, Expect=1e-165]} {Celegans: WBGene00001135, eat-4, Probable vesicular glutamate transporter eat-4, [RH, Score=474, Expect=3e-161]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [RH, Score=583, Expect=0.0]} {RNA1310_14405.1} {RNA815_24257}
22. MligTC455_45351 241 5.02 Mlig455_031191

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.622/0.00310

5.416 0.767 0.969 0.778 0.962 0.995 0.945 Mlig455_031191 {REF} {Length: 2855} {Pfam: Srg family chemoreceptor [PF02118.23, score=28.1]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=26.4]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=26.4]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=49.3, Expect=2e-06]} {Smed: dd_Smed_v6_7534_0_1, dd_Smed_v6_7534_0_1, [Score=54.7, Expect=4e-08]} {RNA1509_20184} {RNA1310_32455} {RNA815_38062}
23. MligTC455_33440 62 1.29 Mlig455_053806, Mlig455_053807

Neo: -

Age: Up-Down-Down

Region-enriched R2: 5.142/0.02950

GRID1 5.411 0.775 0.957 0.815 0.899 0.985 0.980

Mlig455_053806 {REF} {Length: 3070} {Pfam: Ligand-gated ion channel [PF00060.28, score=72.9]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=46.7]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=39.8]; Receptor family ligand binding region [PF01094.30, score=28.6]} {Human: ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=145, Expect=2e-35]} {Mouse: ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=143, Expect=2e-34]} {Dmel: FBgn0038837, CG3822, [Score=126, Expect=2e-29]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=112, Expect=3e-25]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=257, Expect=1e-77]} {RNA1310_13880.2} {RNA815_12458}

Mlig455_053807 {REF} {Length: 3142} {Pfam: Ligand-gated ion channel [PF00060.28, score=79.5]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=46.3]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=38.3]; Receptor family ligand binding region [PF01094.30, score=36.5]} {Human: ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=139, Expect=2e-33]} {Mouse: ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=137, Expect=1e-32]} {Dmel: FBgn0038837, CG3822, [Score=125, Expect=5e-29]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=117, Expect=1e-26]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=259, Expect=2e-78]} {RNA1310_13880.2} {RNA815_12458}
24. MligTC455_46451 229 4.76 Mlig455_017183

Neo: -

Age: Down-Up-Down

Region-specific R2: 5.510

Region-enriched R2: 5.394/0.00018

Regeneration-downregulated R2: -2.986

Regeneration-depleted R2: -2.986

5.41 0.762 0.834 0.878 0.958 0.984 0.994 Mlig455_017183 {REF} {Length: 657} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.6]} {RNA1310_62963} {RNA815_31352}
25. MligTC455_45912 1103 22.98 Mlig455_006912

Neo: -

Age: -

Region-specific R2: 3.366

Region-enriched R2: 1.790/0.00307

5.407 0.905 0.951 0.899 0.943 0.937 0.772 Mlig455_006912 {REF} {Length: 1066} {RNA1509_32903, RNA1509_42927} {RNA1310_38334, RNA1509_42927} {RNA1509_42927, RNA815_18393}
26. MligTC455_46067 548 11.42 Mlig455_054518, Mlig455_055436, Mlig455_055448

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.305/0.04262

GRIK3, GRIK4 5.395 0.914 0.980 0.734 0.820 0.954 0.993

Mlig455_054518 {REF} {Length: 4725} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=91.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.2]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=222, Expect=5e-60]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=222, Expect=6e-60]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=218, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=3e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=215, Expect=1e-57]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=9e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=213, Expect=9e-57]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=224, Expect=2e-60]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=224, Expect=9e-61]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=220, Expect=2e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=215, Expect=1e-57]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=296, Expect=6e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=312, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_14215, RNA1509_40992} {RNA1310_5620.1, RNA1509_14215, RNA1509_40992} {RNA1509_14215, RNA1509_40992, RNA815_1965}

Mlig455_055436 {REF} {Length: 4732} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=6e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=7e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=7e-59]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=3e-58]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=216, Expect=9e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=211, Expect=2e-56]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=226, Expect=3e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=216, Expect=2e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=2e-58]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_40992} {RNA1310_5620.1} {RNA815_1965}

Mlig455_055448 {REF} {Length: 4726} {Pfam: Ligand-gated ion channel [PF00060.28, score=109.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=90.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=81.1]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=219, Expect=9e-59]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=218, Expect=9e-59]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=218, Expect=8e-59]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=217, Expect=2e-58]; ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=216, Expect=7e-58]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=213, Expect=6e-57]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=209, Expect=1e-55]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=225, Expect=4e-61]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=221, Expect=1e-59]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=217, Expect=9e-59]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=216, Expect=5e-58]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=216, Expect=3e-58]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [RH, Score=297, Expect=2e-86]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [RH, Score=313, Expect=2e-94]} {Smed: dd_Smed_v6_16476_0_1, dd_Smed_v6_16476_0_1, [RH, Score=674, Expect=0.0]} {RNA1509_32892, RNA1509_40992} {RNA1310_5620.1, RNA1509_32892} {RNA1509_32892, RNA815_1965}
27. MligTC455_18833 771 16.06 Mlig455_005836

Neo: -

Age: logFC(26M/2M)=-0.422

Region-enriched R2: 2.455/0.00029

5.374 0.914 0.956 0.894 0.940 0.949 0.721 Mlig455_005836 {REF} {Length: 486} {RNA1509_25076} {RNA1310_75647, RNA1509_25076} {RNA1509_25076, RNA815_38932.1}
28. MligTC455_11558 137 2.85 Mlig455_058259

Neo: -

Age: logFC(26M/2M)=-0.792

5.365 0.919 0.758 0.782 0.965 0.984 0.957 Mlig455_058259 {REF} {Length: 896} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=19.9]} {RNA1509_58923} {RNA1310_41706, RNA1509_58923} {RNA1509_58923, RNA815_20876}
29. MligTC455_42391 1050 21.88 Mlig455_010516, Mlig455_061820, Mlig455_061856, Mlig455_061864

Neo: -

Age: Down-Up-Up

5.35 0.962 0.969 0.752 0.925 0.957 0.785

Mlig455_010516 {REF} {Length: 729} {RNA1509_38791} {RNA1310_69853, RNA1509_38791} {RNA1509_38791, RNA815_39199}

Mlig455_061820 {REF} {Length: 705} {RNA1509_38791} {RNA1310_69853} {RNA815_39199}

Mlig455_061856 {REF} {Length: 708} {RNA1509_38791} {RNA1310_69853} {RNA815_39199}

Mlig455_061864 {REF} {Length: 1146} {RNA1509_38791} {RNA1310_69853} {RNA815_39199}
30. MligTC455_16847 1240 25.83 Mlig455_051898, Mlig455_053146

Neo: -

Age: Down-Up-Down

Region-specific R2: 5.478

Region-enriched R2: 5.690/0.00000

PRSS33 5.331 0.712 0.957 0.945 0.893 0.957 0.867

Mlig455_051898 {REF} {Length: 1360} {Pfam: Trypsin [PF00089.28, score=189.8]; Domain of unknown function (DUF1986) [PF09342.13, score=27.3]; Trypsin-like peptidase domain [PF13365.8, score=26.9]} {Human: ENSG00000103355, PRSS33, serine protease 33, [Score=159, Expect=4e-46]} {Mouse: ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=153, Expect=9e-41]; ENSMUSG00000037129, Tmprss13, transmembrane protease, serine 13, [Score=150, Expect=2e-40]; ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [Score=148, Expect=6e-39]; ENSMUSG00000022857, Tmprss15, transmembrane protease, serine 15, [Score=147, Expect=2e-38]} {Dmel: FBgn0036287, CG10663, [Score=146, Expect=1e-38]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [Score=124, Expect=6e-31]} {Smed: dd_Smed_v6_10267_0_1, dd_Smed_v6_10267_0_1, [Score=178, Expect=4e-53]} {RNA1509_29335} {RNA1310_23561} {RNA815_9840}

Mlig455_053146 {REF} {Length: 1448} {Pfam: Trypsin [PF00089.28, score=189.8]; Domain of unknown function (DUF1986) [PF09342.13, score=27.3]; Trypsin-like peptidase domain [PF13365.8, score=26.9]} {Human: ENSG00000103355, PRSS33, serine protease 33, [Score=159, Expect=4e-46]} {Mouse: ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [Score=153, Expect=9e-41]; ENSMUSG00000037129, Tmprss13, transmembrane protease, serine 13, [Score=150, Expect=2e-40]; ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [Score=148, Expect=6e-39]; ENSMUSG00000022857, Tmprss15, transmembrane protease, serine 15, [Score=147, Expect=2e-38]} {Dmel: FBgn0036287, CG10663, [Score=146, Expect=1e-38]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [Score=124, Expect=6e-31]} {Smed: dd_Smed_v6_10267_0_1, dd_Smed_v6_10267_0_1, [Score=178, Expect=4e-53]} {RNA1509_26566, RNA1509_29335} {RNA1310_23561, RNA1509_26566, RNA1509_29335} {RNA1509_26566, RNA1509_29335, RNA815_9840}
31. MligTC455_45020 386 8.05 Mlig455_012422

Neo: -

Age: -

Region-enriched R2: 4.067/0.00066
Region-enriched R3: 2.869/0.01291

AVP 5.317 0.754 0.942 0.896 0.906 0.857 0.962 Mlig455_012422 {REF} {Length: 1252} {Pfam: Neurohypophysial hormones, C-terminal Domain [PF00184.19, score=36.0]} {Human: ENSG00000101200, AVP, arginine vasopressin, [Score=50.4, Expect=4e-08]} {Mouse: ENSMUSG00000037727, Avp, arginine vasopressin, [Score=52.0, Expect=7e-09]} {RNA1509_50574} {RNA1310_26737, RNA1509_50574} {RNA1509_50574, RNA815_23813}
32. MligTC455_49824 466 9.71 Mlig455_036536

Neo: -

Age: -

Region-specific R2: 4.841

Region-enriched R2: 3.862/0.00010

5.308 0.730 0.770 0.929 0.950 0.950 0.979 Mlig455_036536 {REF} {Length: 1139} {Pfam: Nucleoporin FG repeat region [PF13634.8, score=21.2]} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [RH, Score=49.3, Expect=7e-08]} {RNA1509_18714, RNA1509_59524} {RNA1310_41906, RNA1509_18714, RNA1509_59524} {RNA1509_18714, RNA1509_59524, RNA815_24488}
33. MligTC455_43963 1010 21.04 Mlig455_015437

Neo: -

Age: Down-Down-Up

Region-enriched R2: 2.083/0.01168

5.281 0.942 0.944 0.851 0.725 0.847 0.972 Mlig455_015437 {REF} {Length: 612} {RNA1509_32160} {RNA1310_60746, RNA1509_32160} {RNA1509_32160, RNA815_30740}
34. MligTC455_49222 1345 28.02 Mlig455_054810

Neo: -

Age: logFC(26M/2M)=-0.297

Region-specific R2: 6.001

Region-enriched R2: 5.751/0.00000

5.275 0.936 0.929 0.750 0.969 0.948 0.743 Mlig455_054810 {REF} {Length: 1075} {Pfam: Pancreatic hormone peptide [PF00159.20, score=94.2]} {Smed: dd_Smed_v6_16946_0_1, dd_Smed_v6_16946_0_1, [RH, Score=44.3, Expect=7e-07]} {RNA1509_22007, RNA1509_44287, RNA1509_49301} {RNA1310_53171, RNA1509_22007, RNA1509_44287, RNA1509_49301} {RNA1509_22007, RNA1509_44287, RNA1509_49301, RNA815_34467}
35. MligTC455_42314 406 8.46 Mlig455_052727

Neo: -

Age: -

Region-enriched R2: 4.230/0.00183

5.272 0.901 0.837 0.870 0.951 0.976 0.737 Mlig455_052727 {REF} {Length: 1339} {Pfam: Hyaluronidase protein (HylP) [PF07212.13, score=19.1]} {RNA1509_51722} {RNA1310_50605} {RNA815_15783.1}
36. MligTC455_50347 549 11.43 Mlig455_012382

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.390

Region-enriched R2: 6.623/0.00000

5.248 0.768 0.965 0.941 0.778 0.856 0.940 Mlig455_012382 {REF} {Length: 797} {RNA1509_48155} {RNA1310_70969.2, RNA1509_48155} {RNA1509_48155, RNA815_39712}
37. MligTC455_40444 2996 62.42 Mlig455_039527, Mlig455_051318

Neo: -

Age: Down-Up-Down

5.24 0.814 0.992 0.853 0.929 0.889 0.763

Mlig455_039527 {REF} {Length: 710} {RNA1509_7655} {RNA1310_63393} {RNA815_30324}

Mlig455_051318 {REF} {Length: 721} {RNA1509_7655} {RNA1310_63393, RNA1509_7655} {RNA1509_7655, RNA815_30324}
38. MligTC455_38942 10049 209.36 Mlig455_006199, Mlig455_059287, Mlig455_065208

Neo: -

Age: Down-Up-Up

Region-specific R2: 3.098

Region-enriched R2: 2.386/0.00000

Regeneration-downregulated BL: -1.590

Regeneration-depleted BL: -1.590

5.238 0.706 0.776 0.893 0.956 0.971 0.936

Mlig455_006199 {REF} {Length: 1471} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.5]; PBCV-specific basic adaptor domain [PF08789.12, score=19.4]} {RNA1509_46453} {RNA1310_48530} {RNA815_23319.1}

Mlig455_059287 {REF} {Length: 4862} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=25.9]} {RNA1509_58881} {RNA1310_67941, RNA1509_58881} {RNA1509_58881, RNA815_23357}

Mlig455_065208 {REF} {Length: 981} {Pfam: Pheromone biosynthesis activating neuropeptide (PBAN) [PF05874.13, score=24.3]} {RNA1509_18071, RNA1509_58881} {RNA1310_48530, RNA1509_18071} {RNA1509_18071, RNA815_23319.1}
39. MligTC455_34810 109 2.27 Mlig455_024348, Mlig455_024465

Neo: -

Age: -

Region-enriched R2: 5.365/0.04615
Region-enriched R5: 3.627/0.00581

5.228 0.759 0.906 0.733 0.955 0.981 0.894

Mlig455_024348 {REF} {Length: 934} {RNA1310_67817} {RNA815_52313}

Mlig455_024465 {REF} {Length: 1036} {RNA1310_67817} {RNA815_52313}
40. MligTC455_48713 380 7.92 Mlig455_009259, Mlig455_009268

Neo: -

Age: Down-Up-Down

Region-specific R2: 6.962

Region-enriched R2: 4.845/0.00046
Region-enriched R6: 3.343/0.03198

5.211 0.718 0.986 0.856 0.938 0.959 0.754

Mlig455_009259 {REF} {Length: 654} {RNA1509_35038} {RNA1310_72135} {RNA815_37404}

Mlig455_009268 {REF} {Length: 546} {RNA1509_35038} {RNA1310_72135, RNA1509_35038} {RNA1509_35038, RNA815_37404}
41. MligTC455_44354 1240 25.82 Mlig455_001577

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.349

Region-specific R2: 5.143

Region-enriched R2: 4.498/0.00000

Regeneration-downregulated R2: -2.807

Regeneration-depleted R2: -2.807

5.194 0.764 0.879 0.928 0.916 0.977 0.730 Mlig455_001577 {REF} {Length: 1028} {RNA1509_23470, RNA1509_33941, RNA1509_57202} {RNA1310_49541.2, RNA1509_23470, RNA1509_33941, RNA1509_57202} {RNA1509_23470, RNA1509_33941, RNA1509_57202, RNA815_59782}
42. MligTC455_40290 58 1.21 Mlig455_058728

Neo: -

Age: -

Region-enriched R2: 4.464/0.00807
Region-enriched R7: 3.833/0.03206

5.173 0.757 0.952 0.916 0.781 0.863 0.904 Mlig455_058728 {REF} {Length: 1351} {Pfam: CUB domain [PF00431.22, score=48.4]} {RNA1310_48745} {RNA815_23305}
43. MligTC455_46605 388 8.08 Mlig455_032055

Neo: -

Age: -

Region-specific R2: 4.152

5.17 0.822 0.962 0.824 0.766 0.829 0.967 Mlig455_032055 {REF} {Length: 1416} {RNA1310_44339} {RNA815_20624}
44. MligTC455_19070 4394 91.54 Mlig455_017885

Neo: -

Age: -

Region-specific R2: 2.478

Region-enriched R2: 2.025/0.00000

Regeneration-downregulated R2: -1.457

Regeneration-depleted R2: -1.457

5.163 0.817 0.883 0.801 0.971 0.976 0.715 Mlig455_017885 {REF} {Length: 1457} {RNA1509_18484} {RNA1310_63073.1} {RNA815_40214.1}
45. MligTC455_45913 4034 84.05 Mlig455_017927

Neo: -

Age: Down-Up-Up

Region-specific R2: 3.031

Region-enriched R2: 2.341/0.00000
Region-enriched R7: 1.138/0.03064

Regeneration-downregulated BL: -1.976

Regeneration-depleted BL: -1.976

5.161 0.762 0.897 0.887 0.918 0.955 0.742 Mlig455_017927 {REF} {Length: 1006} {RNA1509_22540, RNA1509_32903, RNA1509_3805} {RNA1310_38334, RNA1509_22540, RNA1509_32903, RNA1509_3805} {RNA1509_22540, RNA1509_32903, RNA1509_3805, RNA815_18393}
46. MligTC455_50374 1072 22.34 Mlig455_045630, Mlig455_045678, Mlig455_045690

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.453/0.01939

5.141 0.801 0.930 0.827 0.954 0.721 0.908

Mlig455_045630 {REF} {Length: 996} {RNA1509_39842} {RNA1310_39114} {RNA815_33706.1}

Mlig455_045678 {REF} {Length: 1150} {Pfam: SWR1 chromatin-remodelling complex, sub-unit Swc7 [PF17330.4, score=23.3]; DraK Histidine Kinase N-terminal domain [PF18092.3, score=20.0]} {RNA1509_39842} {RNA1310_39114} {RNA815_33706.1}

Mlig455_045690 {REF} {Length: 1086} {Pfam: SWR1 chromatin-remodelling complex, sub-unit Swc7 [PF17330.4, score=20.9]} {RNA1509_39842} {RNA1310_39114, RNA1509_39842} {RNA1509_39842, RNA815_33706.1}
47. MligTC455_48714 132 2.74 Mlig455_037041

Neo: -

Age: -

Region-enriched R2: 4.531/0.00493

5.139 0.795 0.978 0.861 0.827 0.938 0.740 Mlig455_037041 {REF} {Length: 1099} {RNA1509_35038} {RNA1310_72135} {RNA815_37404}
48. MligTC455_26324 2227 46.4 Mlig455_067472

Neo: -

Age: -

Region-enriched R2: 4.150/0.00003

5.102 0.816 0.953 0.906 0.780 0.878 0.769 Mlig455_067472 {REF} {Length: 918} {Smed: dd_Smed_v6_1588_0_1, dd_Smed_v6_1588_0_1, [Score=42.7, Expect=2e-06]} {RNA1509_6938} {RNA1310_54464.2} {RNA815_23024.2}
49. MligTC455_23150 3195 66.56 Mlig455_009524, Mlig455_009530

Neo: -

Age: -

Region-enriched R2: 3.504/0.00000
Region-enriched R3: 1.656/0.02560

CDK16 5.095 0.777 0.960 0.844 0.814 0.810 0.890

Mlig455_009524 {REF} {Length: 3287} {Pfam: Protein kinase domain [PF00069.27, score=218.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.2]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [RH, Score=463, Expect=7e-159]; ENSG00000059758, CDK17, cyclin dependent kinase 17, [RH, Score=447, Expect=2e-151]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [RH, Score=464, Expect=2e-158]; ENSMUSG00000020015, Cdk17, cyclin-dependent kinase 17, [RH, Score=449, Expect=2e-152]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=362, Expect=2e-118]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [RH, Score=417, Expect=3e-138]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [RH, Score=449, Expect=6e-151]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}

Mlig455_009530 {REF} {Length: 3384} {Pfam: Protein kinase domain [PF00069.27, score=208.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [Score=432, Expect=5e-147]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [Score=431, Expect=4e-146]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=329, Expect=9e-107]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [Score=392, Expect=2e-130]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [Score=411, Expect=6e-137]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}
50. MligTC455_39064 110 2.28 Mlig455_000222, Mlig455_058480

Neo: Irradiation

Age: -

Region-enriched R2: 5.418/0.00017

OSBPL1A 5.092 0.762 0.708 0.852 0.886 0.904 0.980

Mlig455_000222 {REF} {Length: 2113} {Pfam: Oxysterol-binding protein [PF01237.20, score=414.5]} {Human: ENSG00000141447, OSBPL1A, oxysterol binding protein like 1A, [RH, Score=375, Expect=2e-116]; ENSG00000130703, OSBPL2, oxysterol binding protein like 2, [RH, Score=357, Expect=8e-115]} {Mouse: ENSMUSG00000044252, Osbpl1a, oxysterol binding protein-like 1A, [RH, Score=378, Expect=4e-122]; ENSMUSG00000039050, Osbpl2, oxysterol binding protein-like 2, [RH, Score=367, Expect=6e-119]} {Dmel: FBgn0034951, CG3860, [RH, Score=409, Expect=1e-135]} {Celegans: WBGene00008832, obr-2, Oxysterol Binding protein (OSBP) Related, [RH, Score=239, Expect=3e-71]} {Smed: dd_Smed_v6_3179_0_1, dd_Smed_v6_3179_0_1, [RH, Score=385, Expect=3e-126]} {RNA1509_29630} {RNA1310_38654} {RNA815_7740}

Mlig455_058480 {REF} {Length: 2888} {TRANSSPLICED} {Pfam: Oxysterol-binding protein [PF01237.20, score=414.5]} {Human: ENSG00000141447, OSBPL1A, oxysterol binding protein like 1A, [RH, Score=375, Expect=2e-116]; ENSG00000130703, OSBPL2, oxysterol binding protein like 2, [RH, Score=357, Expect=8e-115]} {Mouse: ENSMUSG00000044252, Osbpl1a, oxysterol binding protein-like 1A, [RH, Score=378, Expect=4e-122]; ENSMUSG00000039050, Osbpl2, oxysterol binding protein-like 2, [RH, Score=367, Expect=6e-119]} {Dmel: FBgn0034951, CG3860, [RH, Score=409, Expect=1e-135]} {Celegans: WBGene00008832, obr-2, Oxysterol Binding protein (OSBP) Related, [RH, Score=239, Expect=3e-71]} {Smed: dd_Smed_v6_3179_0_1, dd_Smed_v6_3179_0_1, [RH, Score=385, Expect=3e-126]} {RNA1509_29630} {RNA1310_38654} {RNA815_26411}
51. MligTC455_44025 591 12.31 Mlig455_050980

Neo: -

Age: -

Region-specific R2: 5.366

Region-enriched R2: 5.986/0.00000

5.054 0.770 0.809 0.916 0.748 0.970 0.841 Mlig455_050980 {REF} {Length: 587} {Smed: dd_Smed_v6_2575_0_1, dd_Smed_v6_2575_0_1, [Score=49.7, Expect=7e-09]} {RNA1509_52032} {RNA1310_52449.2} {RNA815_56904}
52. MligTC455_47080 362 7.54 Mlig455_037356

Neo: -

Age: -

Region-enriched R2: 2.691/0.00566

SSUH2 4.951 0.725 0.784 0.825 0.799 0.829 0.989 Mlig455_037356 {REF} {Length: 1984} {Pfam: DnaJ central domain [PF00684.21, score=20.9]} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=189, Expect=3e-56]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=156, Expect=5e-44]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=90.9, Expect=7e-20]} {RNA1509_29510} {RNA1310_15488, RNA1509_29510} {RNA1509_29510, RNA815_5650}
53. MligTC455_26356 62 1.3 Mlig455_042551

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.548

GRIK2 4.837 0.960 0.982 - 0.933 0.965 0.997 Mlig455_042551 {REF} {Length: 2917} {Pfam: Ligand-gated ion channel [PF00060.28, score=82.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=60.7]; Receptor family ligand binding region [PF01094.30, score=32.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=27.3]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=144, Expect=9e-35]; ENSG00000152208, GRID2, glutamate ionotropic receptor delta type subunit 2, [Score=141, Expect=7e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=143, Expect=1e-34]; ENSMUSG00000071424, Grid2, glutamate receptor, ionotropic, delta 2, [Score=142, Expect=2e-34]} {Dmel: FBgn0051201, GluRIIE, Glutamate receptor IIE, [Score=119, Expect=3e-27]} {Celegans: WBGene00001616, glr-5, GLutamate Receptor family (AMPA), [Score=123, Expect=2e-28]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=247, Expect=4e-74]} {RNA1310_21865} {RNA815_26044}
54. MligTC455_41382 65 1.35 Mlig455_022554

Neo: -

Age: -

Region-enriched R2: 5.596/0.01432

4.835 0.960 0.985 - 0.914 0.979 0.997 Mlig455_022554 {REF} {Length: 503} {Pfam: Pancreatic hormone peptide [PF00159.20, score=18.9]} {RNA1310_81495} {RNA815_42745}
55. MligTC455_09510 314 6.55 Mlig455_001134, Mlig455_042048

Neo: -

Age: -

Region-specific R2: 5.291

Region-enriched R2: 5.151/0.00029

4.83 0.982 0.989 0.928 0.948 0.983 -

Mlig455_001134 {REF} {Length: 485} {Pfam: Fingers domain of DNA polymerase lambda [PF10391.11, score=26.9]} {RNA1310_8738.1} {RNA815_21682.1}

Mlig455_042048 {REF} {Length: 1550} {Pfam: Fingers domain of DNA polymerase lambda [PF10391.11, score=32.1]} {Dmel: FBgn0036416, CG7924, [RH, Score=61.2, Expect=1e-10]} {RNA1509_51261} {RNA1310_8738.1} {RNA815_21682.1}
56. MligTC455_17363 62 1.28 Mlig455_003936

Neo: -

Age: -

4.826 0.960 - 0.926 0.965 0.978 0.997 Mlig455_003936 {REF} {Length: 1252} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=45.9]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=26.4]} {RNA1310_47889} {RNA815_24646}
57. MligTC455_29412 46 0.96 Mlig455_000627, Mlig455_008268, Mlig455_040614

Neo: -

Age: Up-Down-Up

4.798 - 0.926 0.965 0.970 0.937 1.000

Mlig455_000627 {REF} {Length: 1331} {RNA1310_62571} {RNA815_30942}

Mlig455_008268 {REF} {Length: 1779} {RNA1509_47298} {RNA1310_98344} {RNA815_10804.1}

Mlig455_040614 {REF} {Length: 1016}
58. MligTC455_39544 611 12.73 Mlig455_001809, Mlig455_001836, Mlig455_062227, Mlig455_062236

Neo: -

Age: -

Region-specific R2: 8.576

Region-enriched R2: 8.112/0.00016

4.784 0.925 0.977 0.971 0.969 - 0.942

Mlig455_001809 {REF} {Length: 1067} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}

Mlig455_001836 {REF} {Length: 1065} {RNA1509_52939} {RNA1310_72581, RNA1509_52939} {RNA1509_52939, RNA815_24546}

Mlig455_062227 {REF} {Length: 3520} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}

Mlig455_062236 {REF} {Length: 620} {RNA1509_52939} {RNA1310_72581} {RNA815_24546}
59. MligTC455_44966 574 11.95 Mlig455_036578, Mlig455_057773

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.756

Region-specific R2: 7.016

Region-enriched R2: 7.690/0.00000

4.773 0.959 - 0.863 0.969 0.985 0.997

Mlig455_036578 {REF} {Length: 1101} {RNA1509_34765} {RNA1310_57079} {RNA815_29388}

Mlig455_057773 {REF} {Length: 629} {RNA1509_34765} {RNA1310_57079, RNA1509_34765} {RNA1509_34765, RNA815_29388}
60. MligTC455_18945 41 0.86 Mlig455_031602

Neo: -

Age: -

4.764 - 0.970 0.869 0.970 0.958 0.997 Mlig455_031602 {REF} {Length: 914} {RNA1310_75361} {RNA815_24378}
61. MligTC455_45487 110 2.3 Mlig455_004129, Mlig455_060457

Neo: -

Age: -

4.756 0.960 0.982 - 0.873 0.946 0.995

Mlig455_004129 {REF} {Length: 1131} {Pfam: PAN domain [PF00024.28, score=18.8]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1310_37660} {RNA815_17816.1}

Mlig455_060457 {REF} {Length: 1507} {Pfam: PAN domain [PF00024.28, score=19.5]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_54623} {RNA1310_33480} {RNA815_17816.1}
62. MligTC455_43210 1513 31.51 Mlig455_059969

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.253

Region-specific R2: 4.268

Region-enriched R2: 4.051/0.00000

4.743 - 0.918 0.962 0.983 0.955 0.925 Mlig455_059969 {REF} {Length: 1263} {Pfam: Pancreatic hormone peptide [PF00159.20, score=46.6]} {Smed: dd_Smed_v6_16946_0_1, dd_Smed_v6_16946_0_1, [Score=41.6, Expect=1e-05]} {RNA1509_21159, RNA1509_26888, RNA1509_32920} {RNA1310_28339, RNA1509_21159, RNA1509_26888, RNA1509_32920} {RNA1509_21159, RNA1509_26888, RNA1509_32920, RNA815_20007.1}
63. MligTC455_35813 35 0.73 Mlig455_013562, Mlig455_013615

Neo: -

Age: -

Region-enriched R2: 7.733/0.00085

NPR2 4.736 0.960 0.978 0.916 0.888 0.994 -

Mlig455_013562 {REF} {Length: 3105} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=187.6]; Nitrate and nitrite sensing [PF08376.12, score=108.9]; Heme NO binding associated [PF07701.16, score=29.1]} {Human: ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=251, Expect=2e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=247, Expect=6e-69]; ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=241, Expect=1e-66]} {Mouse: ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=252, Expect=1e-73]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=248, Expect=2e-69]} {Dmel: FBgn0053958, CG33958, [Score=330, Expect=3e-102]} {Celegans: WBGene00001533, gcy-6, Receptor-type guanylate cyclase gcy-6, [Score=231, Expect=7e-64]} {Smed: dd_Smed_v6_11767_0_1, dd_Smed_v6_11767_0_1, [Score=244, Expect=3e-68]} {RNA1310_16282} {RNA815_27869}

Mlig455_013615 {REF} {Length: 2993} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=187.7]; Nitrate and nitrite sensing [PF08376.12, score=109.5]; Heme NO binding associated [PF07701.16, score=29.1]} {Human: ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=251, Expect=2e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=246, Expect=8e-69]; ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=241, Expect=1e-66]} {Mouse: ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=252, Expect=9e-74]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=247, Expect=2e-69]} {Dmel: FBgn0053958, CG33958, [Score=331, Expect=1e-102]} {Celegans: WBGene00001533, gcy-6, Receptor-type guanylate cyclase gcy-6, [Score=231, Expect=8e-64]} {Smed: dd_Smed_v6_11767_0_1, dd_Smed_v6_11767_0_1, [Score=244, Expect=3e-68]} {RNA1310_16282} {RNA815_33407}
64. MligTC455_21033 1129 23.52 Mlig455_010672

Neo: -

Age: logFC(26M/2M)=0.356

Region-specific R2: 3.326

Region-enriched R2: 2.739/0.00000

Regeneration-downregulated R2: -1.967

Regeneration-depleted R2: -1.967

4.725 0.961 0.942 0.966 0.956 0.900 - Mlig455_010672 {REF} {Length: 829} {RNA1509_30331, RNA1509_45731} {RNA1310_60944, RNA1509_30331, RNA1509_45731} {RNA1509_30331, RNA1509_45731, RNA815_27381.1}
65. MligTC455_43714 152 3.18 Mlig455_000684, Mlig455_000736

Neo: -

Age: -

4.714 - 0.982 0.801 0.970 0.964 0.997

Mlig455_000684 {REF} {Length: 796} {Pfam: WSC domain [PF01822.21, score=42.8]} {RNA1310_46313} {RNA815_23250}

Mlig455_000736 {REF} {Length: 797} {Pfam: WSC domain [PF01822.21, score=42.8]} {RNA1310_46313} {RNA815_23250}
66. MligTC455_17218 37 0.78 Mlig455_053853

Neo: -

Age: -

4.707 0.907 - 0.867 0.965 0.971 0.997 Mlig455_053853 {REF} {Length: 1743} {RNA1310_61921}
67. MligTC455_19249 90 1.86 Mlig455_054092

Neo: -

Age: Down-Up-Up

Region-enriched R2: 7.298/0.00139

4.701 0.924 - 0.904 0.965 0.958 0.950 Mlig455_054092 {REF} {Length: 667} {TRANSSPLICED} {RNA1509_57448} {RNA1310_51394, RNA1509_57448} {RNA1509_57448, RNA815_26076}
68. MligTC455_43715 48 0.99 Mlig455_034191

Neo: -

Age: Down-Up-Down

Region-enriched R2: 7.969/0.00817

4.7 - 0.978 0.793 0.960 0.972 0.997 Mlig455_034191 {REF} {Length: 895} {Pfam: WSC domain [PF01822.21, score=39.9]; PAN domain [PF14295.8, score=21.0]; PAN domain [PF00024.28, score=19.9]} {RNA1310_46313} {RNA815_23250}
69. MligTC455_17021 49 1.02 Mlig455_030263

Neo: -

Age: -

4.7 0.945 0.976 0.864 - 0.931 0.984 Mlig455_030263 {REF} {Length: 566} {TRANSSPLICED} {Pfam: Galactosyltransferase [PF01762.23, score=23.7]} {Dmel: FBgn0000221, brn, brainiac, [Score=45.8, Expect=1e-06]} {RNA1310_35735} {RNA815_59866}
70. MligTC455_47780 214 4.46 Mlig455_018842, Mlig455_018853

Neo: -

Age: -

4.696 0.882 0.980 0.929 0.940 0.965 -

Mlig455_018842 {REF} {Length: 500} {RNA1509_48336} {RNA1310_73351} {RNA815_41082}

Mlig455_018853 {REF} {Length: 593} {RNA1509_48336} {RNA1310_73351, RNA1509_48336} {RNA1509_48336, RNA815_41082}
71. MligTC455_49451 16 0.34 Mlig455_030374

Neo: -

Age: -

NOX5 4.696 - 0.982 0.816 0.932 0.969 0.997 Mlig455_030374 {REF} {Length: 890} {Pfam: EF hand [PF00036.34, score=93.4]; EF-hand domain [PF13405.8, score=86.0]; EF hand [PF13202.8, score=73.1]; EF-hand domain pair [PF13499.8, score=70.3]; EF-hand domain pair [PF13833.8, score=49.3]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=29.0]; EF-hand domain [PF14658.8, score=23.2]; Caleosin related protein [PF05042.15, score=20.4]; EF-hand domain [PF17958.3, score=19.8]} {Human: ENSG00000255346, NOX5, NADPH oxidase 5, [Score=67.4, Expect=2e-13]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=63.5, Expect=3e-13]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=63.2, Expect=4e-13]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=63.2, Expect=4e-13]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=63.2, Expect=4e-13]} {Dmel: FBgn0033238, azot, ahuizotl, [Score=64.3, Expect=1e-13]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=62.4, Expect=6e-13]} {Smed: dd_Smed_v6_15455_0_1, dd_Smed_v6_15455_0_1, [RH, Score=101, Expect=2e-28]} {RNA1310_74457}
72. MligTC455_16610 98 2.05 Mlig455_069894

Neo: -

Age: -

Region-enriched R2: 5.254/0.03136

WSCD2 4.672 - 0.957 0.920 0.914 0.884 0.997 Mlig455_069894 {REF} {Length: 827} {Pfam: WSC domain [PF01822.21, score=59.2]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=55.1, Expect=4e-09]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=47.8, Expect=9e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=52.4, Expect=2e-08]} {RNA1509_46267} {RNA1310_46146} {RNA815_32275.1}
73. MligTC455_32644 41 0.86 Mlig455_043770, Mlig455_043786

Neo: -

Age: -

Region-enriched R2: 6.705/0.00336

4.665 0.954 0.984 0.840 - 0.890 0.997

Mlig455_043770 {REF} {Length: 1011} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.8, Expect=3e-11]} {RNA1509_35604} {RNA1310_57814} {RNA815_29718}

Mlig455_043786 {REF} {Length: 1348} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
74. MligTC455_45021 381 7.95 Mlig455_046686

Neo: -

Age: Down-Up-Up

Region-enriched R2: 3.428/0.03156

AVP 4.664 - 0.943 0.902 0.917 0.934 0.968 Mlig455_046686 {REF} {Length: 1388} {Pfam: Neurohypophysial hormones, C-terminal Domain [PF00184.19, score=36.2]} {Human: ENSG00000101200, AVP, arginine vasopressin, [Score=54.3, Expect=2e-09]} {Mouse: ENSMUSG00000037727, Avp, arginine vasopressin, [Score=53.1, Expect=3e-09]} {RNA1509_50574} {RNA1310_38922} {RNA815_23813}
75. MligTC455_34524 155 3.22 Mlig455_021291

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.905

Region-enriched R2: 4.200/0.01842

4.656 0.946 0.824 0.957 0.954 - 0.975 Mlig455_021291 {REF} {Length: 1478} {NoTransDecoderORF} {RNA1509_56543} {RNA1310_26920, RNA1509_56543} {RNA1509_56543, RNA815_11718}
76. MligTC455_10899 46 0.95 Mlig455_013784, Mlig455_013915

Neo: -

Age: -

4.646 - 0.981 0.917 0.924 0.845 0.979

Mlig455_013784 {REF} {Length: 1362} {Pfam: Glycine rich protein [PF12810.9, score=20.8]} {RNA1509_28715} {RNA1310_91773} {RNA815_35307}

Mlig455_013915 {REF} {Length: 1516} {Pfam: Glycine rich protein [PF12810.9, score=20.3]} {RNA1509_28715} {RNA1310_91773} {RNA815_35307}
77. MligTC455_12183 53 1.11 Mlig455_004166, Mlig455_004190

Neo: -

Age: -

Region-enriched R2: 4.930/0.01881

4.643 0.951 - 0.857 0.942 0.956 0.937

Mlig455_004166 {REF} {Length: 2818} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=57.4]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=29.1]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=55.5, Expect=1e-08]} {Smed: dd_Smed_v6_70862_0_1, dd_Smed_v6_70862_0_1, [Score=60.8, Expect=8e-12]} {RNA1310_64973} {RNA815_58453}

Mlig455_004190 {REF} {Length: 2742} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.7]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=28.6]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=56.2, Expect=1e-08]} {Smed: dd_Smed_v6_70862_0_1, dd_Smed_v6_70862_0_1, [Score=60.8, Expect=1e-11]} {RNA1310_62602} {RNA815_58453}
78. MligTC455_46452 134 2.79 Mlig455_048151

Neo: -

Age: -

Region-specific R2: 6.389

Region-enriched R2: 7.075/0.00014

Regeneration-downregulated R2: -3.162

Regeneration-depleted R2: -3.162

4.641 - 0.801 0.951 0.959 0.975 0.955 Mlig455_048151 {REF} {Length: 618} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=25.7]} {RNA1310_62963} {RNA815_31352}
79. MligTC455_19079 218 4.54 Mlig455_008746, Mlig455_008760

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.705

Region-enriched R2: 6.864/0.00152

4.639 - 0.900 0.947 0.932 0.875 0.985

Mlig455_008746 {REF} {Length: 652} {RNA1310_75395.1} {RNA815_42524}

Mlig455_008760 {REF} {Length: 1051} {RNA1310_75395.1} {RNA815_42524}
80. MligTC455_18333 273 5.7 Mlig455_010935

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.059/0.00307

4.637 0.931 - 0.842 0.967 0.950 0.947 Mlig455_010935 {REF} {Length: 510} {RNA1310_33328.2} {RNA815_15093.1}
81. MligTC455_43642 2199 45.81 Mlig455_018475

Neo: -

Age: Down-Up-Up

Region-specific R2: 2.701

Region-enriched R2: 2.110/0.00000

4.634 0.896 0.938 0.885 0.958 0.957 - Mlig455_018475 {REF} {Length: 949} {RNA1509_30521} {RNA1310_47277.3, RNA1509_30521} {RNA1509_30521, RNA815_19145.1}
82. MligTC455_14483 140 2.92 Mlig455_028240

Neo: -

Age: -

Region-enriched R2: 6.203/0.04837

4.633 0.960 - 0.765 0.970 0.945 0.993 Mlig455_028240 {REF} {Length: 728} {RNA1310_111517} {RNA815_9716}
83. MligTC455_34525 52 1.08 Mlig455_021566

Neo: -

Age: Down-Up-Down

GNAI1 4.629 0.950 - 0.966 0.902 0.828 0.983 Mlig455_021566 {REF} {Length: 3532} {Pfam: G-protein alpha subunit [PF00503.22, score=404.9]; ADP-ribosylation factor family [PF00025.23, score=56.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=20.1]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.4]} {Human: ENSG00000127955, GNAI1, G protein subunit alpha i1, [Score=486, Expect=2e-171]; ENSG00000114353, GNAI2, G protein subunit alpha i2, [Score=481, Expect=3e-169]; ENSG00000065135, GNAI3, G protein subunit alpha i3, [Score=474, Expect=1e-166]} {Mouse: ENSMUSG00000057614, Gnai1, guanine nucleotide binding protein (G protein), alpha inhibiting 1, [Score=486, Expect=2e-171]; ENSMUSG00000032562, Gnai2, guanine nucleotide binding protein (G protein), alpha inhibiting 2, [Score=475, Expect=5e-167]; ENSMUSG00000000001, Gnai3, guanine nucleotide binding protein (G protein), alpha inhibiting 3, [Score=474, Expect=1e-166]} {Dmel: FBgn0001104, Galphai, G protein alpha i subunit, [Score=468, Expect=2e-164]} {Celegans: WBGene00001648, goa-1, Guanine nucleotide-binding protein G(o) subunit alpha, [Score=446, Expect=5e-156]} {Smed: dd_Smed_v6_12112_0_1, dd_Smed_v6_12112_0_1, [RH, Score=598, Expect=0.0]} {RNA1509_45426} {RNA1310_26920, RNA1509_45426} {RNA1509_45426, RNA815_11718}
84. MligTC455_18748 104 2.17 Mlig455_024985, Mlig455_024999

Neo: -

Age: -

Region-enriched R2: 6.002/0.00016
Region-enriched R4: 3.433/0.02745

GRIK4 4.623 0.908 0.791 - 0.970 0.955 0.999

Mlig455_024985 {REF} {Length: 1514} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_47299} {RNA815_38321}

Mlig455_024999 {REF} {Length: 3567} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_7578, RNA1509_35538} {RNA1509_35538, RNA815_4987}
85. MligTC455_43072 81 1.68 Mlig455_042521

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.590/0.02161

4.623 - 0.981 0.859 0.963 0.831 0.989 Mlig455_042521 {REF} {Length: 1049} {RNA1509_46101} {RNA1310_32444} {RNA815_30668}
86. MligTC455_49334 86 1.78 Mlig455_037751

Neo: -

Age: -

4.622 0.940 0.982 0.733 0.970 - 0.997 Mlig455_037751 {REF} {Length: 708} {RNA1509_25826} {RNA1310_47741} {RNA815_23874}
87. MligTC455_17445 888 18.5 Mlig455_000400

Neo: -

Age: logFC(26M/2M)=0.513

Region-specific R2: 4.076

Region-enriched R2: 3.306/0.00000

4.617 0.869 0.910 0.931 0.961 0.946 - Mlig455_000400 {REF} {Length: 711} {RNA1509_36036, RNA1509_39429} {RNA1310_64870, RNA1509_36036, RNA1509_39429} {RNA1509_36036, RNA1509_39429, RNA815_46241}
88. MligTC455_18099 24 0.51 Mlig455_036525

Neo: -

Age: -

PPA1 4.614 0.960 - 0.833 0.882 0.950 0.989 Mlig455_036525 {REF} {Length: 1911} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1310_57333.1} {RNA815_22340}
89. MligTC455_39988 83 1.73 Mlig455_062081

Neo: -

Age: -

4.61 0.936 0.975 0.963 0.740 - 0.996 Mlig455_062081 {REF} {Length: 447} {NoTransDecoderORF} {RNA1509_50426} {RNA1310_88257} {RNA815_17173.4}
90. MligTC455_50355 38 0.79 Mlig455_057631

Neo: -

Age: -

Region-enriched R2: 7.639/0.01837

4.603 0.901 0.912 0.862 0.934 - 0.994 Mlig455_057631 {REF} {Length: 1003} {Pfam: WSC domain [PF01822.21, score=45.2]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=6e-06]} {RNA1310_44307} {RNA815_33128}
91. MligTC455_43454 36 0.74 Mlig455_043999

Neo: -

Age: -

4.603 0.952 0.898 - 0.960 0.878 0.915 Mlig455_043999 {REF} {Length: 2456} {Dmel: FBgn0259222, CG42322, [RH, Score=101, Expect=3e-22]} {Smed: dd_Smed_v6_18554_0_1, dd_Smed_v6_18554_0_1, [Score=82.4, Expect=1e-17]} {RNA1310_20749} {RNA815_38231}
92. MligTC455_53546 130 2.72 Mlig455_013326, Mlig455_013334

Neo: -

Age: -

Region-enriched R2: 6.753/0.01892

MMP9 4.598 - 0.826 0.920 0.929 0.954 0.969

Mlig455_013326 {REF} {Length: 1449} {Pfam: Fibronectin type II domain [PF00040.21, score=92.5]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=87.8, Expect=3e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=82.4, Expect=1e-16]; ENSMUSG00000031740, Mmp2, matrix metallopeptidase 2, [RH, Score=78.6, Expect=2e-15]} {Smed: dd_Smed_v6_14558_0_1, dd_Smed_v6_14558_0_1, [RH, Score=138, Expect=3e-38]} {RNA1310_38631} {RNA815_51136}

Mlig455_013334 {REF} {Length: 1398} {Pfam: Fibronectin type II domain [PF00040.21, score=92.1]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=89.4, Expect=1e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=84.0, Expect=4e-17]} {Smed: dd_Smed_v6_12601_0_1, dd_Smed_v6_12601_0_1, [RH, Score=140, Expect=2e-38]} {RNA1310_38631} {RNA815_51136}
93. MligTC455_50594 440 9.18 Mlig455_010362

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.701

Region-enriched R2: 4.104/0.00000

4.592 - 0.966 0.877 0.925 0.915 0.909 Mlig455_010362 {REF} {Length: 685} {RNA1509_30018} {RNA1310_56512.2} {RNA815_28562}
94. MligTC455_41130 1186 24.72 Mlig455_000166, Mlig455_000179, Mlig455_067712

Neo: -

Age: Down-Up-Down

Region-specific R2: 5.626

Region-enriched R2: 4.906/0.00009

Regeneration-downregulated R3: -5.200

Regeneration-depleted R3: -5.200

4.587 - 0.909 0.936 0.817 0.928 0.997

Mlig455_000166 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}

Mlig455_000179 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}

Mlig455_067712 {REF} {Length: 479} {RNA1509_36590} {RNA1310_65705}
95. MligTC455_14598 52 1.07 Mlig455_058970

Neo: -

Age: -

4.583 - 0.938 0.879 0.867 0.906 0.993 Mlig455_058970 {REF} {Length: 1038} {RNA1310_39570} {RNA815_52309}
96. MligTC455_10966 15 0.31 Mlig455_013154

Neo: -

Age: -

4.581 - 0.983 0.756 0.859 0.987 0.996 Mlig455_013154 {REF} {Length: 827} {Pfam: Lectin C-type domain [PF00059.23, score=21.8]} {RNA1509_20946} {RNA1310_65161} {RNA815_4785.1}
97. MligTC455_44954 1303 27.14 Mlig455_029595, Mlig455_070648

Neo: Int S/G2/M

Age: Down-Up-Up, logFC(26M/2M)=1.023

Region-specific R2: 8.846

Region-enriched R2: 10.764/0.00000

4.576 0.860 0.881 0.880 0.970 0.985 -

Mlig455_029595 {REF} {Length: 484} {Pfam: Pancreatic hormone peptide [PF00159.20, score=30.3]} {Smed: dd_Smed_v6_6375_0_1, dd_Smed_v6_6375_0_1, [RH, Score=47.4, Expect=3e-08]} {RNA1509_20871} {RNA1310_66833.2} {RNA815_41767}

Mlig455_070648 {REF} {Length: 484} {Pfam: Pancreatic hormone peptide [PF00159.20, score=30.3]} {Smed: dd_Smed_v6_6375_0_1, dd_Smed_v6_6375_0_1, [RH, Score=47.4, Expect=3e-08]} {RNA1509_20871, RNA1509_39484} {RNA1310_66833.2, RNA1509_20871, RNA1509_39484} {RNA1509_20871, RNA1509_39484, RNA815_41767}
98. MligTC455_24407 222 4.63 Mlig455_044026

Neo: -

Age: Down-Up-Up

Region-specific R2: 3.725

Region-enriched R2: 3.414/0.00001

4.567 0.845 0.930 0.896 0.960 0.936 - Mlig455_044026 {REF} {Length: 503} {RNA1509_54091} {RNA1310_68348.1} {RNA815_33570.1}
99. MligTC455_43643 2324 48.41 Mlig455_065102

Neo: -

Age: -

Region-specific R2: 2.496

Region-enriched R2: 1.834/0.00001

Regeneration-downregulated R6: -1.642

Regeneration-depleted R6: -1.642

4.558 0.911 0.937 0.782 0.962 0.966 - Mlig455_065102 {REF} {Length: 850} {RNA1509_16353, RNA1509_24268} {RNA1310_47277.1, RNA1509_24268} {RNA1509_24268, RNA815_19145.2}
100. MligTC455_24406 204 4.25 Mlig455_043947

Neo: -

Age: -

Region-specific R2: 3.852

Region-enriched R2: 3.953/0.00003

4.553 0.891 0.975 0.944 0.934 0.809 - Mlig455_043947 {REF} {Length: 1609} {RNA1509_54091} {RNA1310_68348.1, RNA1509_54091} {RNA1509_54091, RNA815_33570.1}

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