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Results for MligTC455_19164

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_19164 643 13.39 Mlig455_066812

Neo: -

Age: -

 TBL2 Mlig455_066812 {REF} {Length: 2791} {Pfam: WD domain, G-beta repeat [PF00400.34, score=72.6]} {Human: ENSG00000106638, TBL2, transducin beta like 2, [RH, Score=296, Expect=4e-96]} {Mouse: ENSMUSG00000005374, Tbl2, transducin (beta)-like 2, [RH, Score=283, Expect=2e-90]} {Dmel: FBgn0032030, Wdr82, WD repeat domain 82, [Score=51.2, Expect=9e-07]} {Celegans: WBGene00009784, F46C5.9, [RH, Score=174, Expect=5e-49]} {Smed: dd_Smed_v6_4372_0_1, dd_Smed_v6_4372_0_1, [RH, Score=249, Expect=1e-77]} {RNA1509_12484, RNA1509_27098, RNA1509_8303} {RNA1310_11971, RNA1509_12484, RNA1509_27098, RNA1509_8303} {RNA1509_12484, RNA1509_27098, RNA1509_8303, RNA815_4594}

Cumulative graph for MligTC455_19164

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.746 3.841 0.08143 0.62311
RegionR2 -1.066 3.841 0.05179 0.27204
RegionR3 -0.41 3.841 0.35306 0.88872
RegionR4 1.028 3.841 0.05043 0.19384
RegionR5 0.573 3.841 0.14351 0.39135
RegionR6 -0.23 3.841 0.60397 1.00000
RegionR7 -0.747 3.841 0.21301 0.82896
RegionR8 -0.894 3.841 0.22279 0.83054

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.214 3.841 0.85306 1.00000
RegenerationR2 0.522 3.841 0.29352 0.73644
RegenerationR3 0.329 3.841 0.53915 0.87715
RegenerationR4 -0.397 3.841 0.44775 0.84067
RegenerationR5 -0.165 3.841 0.73316 0.96517
RegenerationR6 0.067 3.841 0.90420 1.00000
RegenerationBL 0.415 3.841 0.52051 0.88218
RegenerationTP 0.384 3.841 0.58058 0.95003


Genes with expression patterns similar to MligTC455_19164

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_19164 643 13.39 Mlig455_066812

Neo: -

Age: -

 TBL2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_066812 {REF} {Length: 2791} {Pfam: WD domain, G-beta repeat [PF00400.34, score=72.6]} {Human: ENSG00000106638, TBL2, transducin beta like 2, [RH, Score=296, Expect=4e-96]} {Mouse: ENSMUSG00000005374, Tbl2, transducin (beta)-like 2, [RH, Score=283, Expect=2e-90]} {Dmel: FBgn0032030, Wdr82, WD repeat domain 82, [Score=51.2, Expect=9e-07]} {Celegans: WBGene00009784, F46C5.9, [RH, Score=174, Expect=5e-49]} {Smed: dd_Smed_v6_4372_0_1, dd_Smed_v6_4372_0_1, [RH, Score=249, Expect=1e-77]} {RNA1509_12484, RNA1509_27098, RNA1509_8303} {RNA1310_11971, RNA1509_12484, RNA1509_27098, RNA1509_8303} {RNA1509_12484, RNA1509_27098, RNA1509_8303, RNA815_4594}
2. MligTC455_42933 1178 24.54 Mlig455_070302

Neo: -

Age: logFC(26M/2M)=-0.391

 TPRG1 2.676 - - - 0.952 0.855 0.869 Mlig455_070302 {REF} {Length: 1928} {TRANSSPLICED} {Pfam: Inositol phosphatase [PF12456.10, score=52.1]} {Human: ENSG00000188001, TPRG1, tumor protein p63 regulated 1, [RH, Score=119, Expect=9e-32]} {Mouse: ENSMUSG00000029030, Tprgl, transformation related protein 63 regulated like, [RH, Score=108, Expect=1e-27]; ENSMUSG00000048399, Tprg, transformation related protein 63 regulated, [RH, Score=107, Expect=2e-27]} {Smed: dd_Smed_v6_2044_0_1, dd_Smed_v6_2044_0_1, [RH, Score=116, Expect=2e-31]} {RNA1509_36410, RNA1509_40487, RNA1509_42133, RNA1509_43585, RNA1509_6006} {RNA1310_13002.2, RNA1509_36410, RNA1509_42133, RNA1509_43585, RNA1509_6006} {RNA1509_36410, RNA1509_42133, RNA1509_43585, RNA1509_6006, RNA815_4952.1}
3. MligTC455_41904 1261 26.28 Mlig455_033790, Mlig455_033840

Neo: -

Age: -

Regeneration-upregulated BL: 1.850

Regeneration-enriched BL: 1.850

 TBL1XR1 2.637 - - - 0.963 0.925 0.749

Mlig455_033790 {REF} {Length: 3142} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=165.9]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=99.7]; Eukaryotic translation initiation factor eIF2A [PF08662.13, score=38.0]; LisH [PF08513.13, score=36.0]} {Human: ENSG00000177565, TBL1XR1, transducin beta like 1 X-linked receptor 1, [RH, Score=718, Expect=0.0]; ENSG00000101849, TBL1X, transducin beta like 1 X-linked, [RH, Score=702, Expect=0.0]; ENSG00000092377, TBL1Y, transducin beta like 1 Y-linked, [RH, Score=693, Expect=0.0]} {Mouse: ENSMUSG00000027630, Tbl1xr1, transducin (beta)-like 1X-linked receptor 1, [RH, Score=723, Expect=0.0]; ENSMUSG00000025246, Tbl1x, transducin (beta)-like 1 X-linked, [RH, Score=709, Expect=0.0]} {Dmel: FBgn0263933, ebi, [RH, Score=584, Expect=0.0]} {Celegans: WBGene00021074, W07E6.2, [Score=118, Expect=2e-28]} {Smed: dd_Smed_v6_3247_0_1, dd_Smed_v6_3247_0_1, [RH, Score=510, Expect=1e-176]} {RNA1509_6947} {RNA1310_1131} {RNA815_1434.1}

Mlig455_033840 {REF} {Length: 3152} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=164.5]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=99.4]; Eukaryotic translation initiation factor eIF2A [PF08662.13, score=37.8]; LisH [PF08513.13, score=36.0]} {Human: ENSG00000177565, TBL1XR1, transducin beta like 1 X-linked receptor 1, [RH, Score=716, Expect=0.0]; ENSG00000101849, TBL1X, transducin beta like 1 X-linked, [RH, Score=700, Expect=0.0]; ENSG00000092377, TBL1Y, transducin beta like 1 Y-linked, [RH, Score=691, Expect=0.0]} {Mouse: ENSMUSG00000027630, Tbl1xr1, transducin (beta)-like 1X-linked receptor 1, [RH, Score=721, Expect=0.0]; ENSMUSG00000025246, Tbl1x, transducin (beta)-like 1 X-linked, [RH, Score=706, Expect=0.0]} {Dmel: FBgn0263933, ebi, [RH, Score=583, Expect=0.0]} {Celegans: WBGene00021074, W07E6.2, [Score=118, Expect=2e-28]} {Smed: dd_Smed_v6_3247_0_1, dd_Smed_v6_3247_0_1, [RH, Score=509, Expect=3e-176]} {RNA1509_49396, RNA1509_6947} {RNA1310_1131, RNA1509_49396, RNA1509_6947} {RNA1509_49396, RNA1509_6947, RNA815_1434.1}
4. MligTC455_19324 1062 22.13 Mlig455_045112

Neo: Int S/G2/M

Age: -

 KCTD21 2.549 - - - 0.959 0.846 0.744 Mlig455_045112 {REF} {Length: 1839} {TRANSSPLICED} {Pfam: BTB/POZ domain [PF02214.24, score=57.7]; N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) [PF07221.13, score=18.0]} {Human: ENSG00000188997, KCTD21, potassium channel tetramerization domain containing 21, [RH, Score=102, Expect=7e-27]} {Mouse: ENSMUSG00000044952, Kctd21, potassium channel tetramerisation domain containing 21, [RH, Score=103, Expect=4e-26]} {Dmel: FBgn0038839, Ktl, Kctd12-like, [Score=86.7, Expect=4e-20]} {Celegans: WBGene00014848, VM106R.1, [Score=82.4, Expect=4e-18]} {Smed: dd_Smed_v6_8654_0_1, dd_Smed_v6_8654_0_1, [RH, Score=192, Expect=5e-61]} {RNA1509_8015} {RNA1310_35464.2} {RNA815_25284}
5. MligTC455_38258 788 16.41 Mlig455_018434

Neo: -

Age: -

 PAK1 2.49 - - 0.802 - 0.957 0.731 Mlig455_018434 {REF} {Length: 4285} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=242.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=146.9]; P21-Rho-binding domain [PF00786.30, score=75.5]; Fungal protein kinase [PF17667.3, score=23.3]} {Human: ENSG00000149269, PAK1, p21 (RAC1) activated kinase 1, [RH, Score=572, Expect=0.0]} {Mouse: ENSMUSG00000030774, Pak1, p21 (RAC1) activated kinase 1, [RH, Score=572, Expect=0.0]; ENSMUSG00000031284, Pak3, p21 (RAC1) activated kinase 3, [RH, Score=560, Expect=0.0]; ENSMUSG00000022781, Pak2, p21 (RAC1) activated kinase 2, [RH, Score=555, Expect=0.0]} {Dmel: FBgn0267698, Pak, p21-activated kinase, [RH, Score=508, Expect=2e-171]} {Celegans: WBGene00003911, pak-1, Serine/threonine-protein kinase pak-1, [RH, Score=446, Expect=3e-149]} {Smed: dd_Smed_v6_4784_0_1, dd_Smed_v6_4784_0_1, [RH, Score=473, Expect=8e-159]} {RNA1509_56925, RNA1509_9774} {RNA1310_10491.1, RNA1509_56925, RNA1509_9774} {RNA1509_56925, RNA1509_9774, RNA815_10119}
6. MligTC455_36102 672 13.99 Mlig455_043535

Neo: -

Age: -

 CUX1 2.43 - - 0.743 0.979 - 0.708 Mlig455_043535 {REF} {Length: 4531} {Pfam: CUT domain [PF02376.17, score=229.5]; Homeodomain [PF00046.31, score=53.4]; Homeobox KN domain [PF05920.13, score=27.9]} {Human: ENSG00000257923, CUX1, cut like homeobox 1, [Score=191, Expect=6e-49]; ENSG00000111249, CUX2, cut like homeobox 2, [Score=187, Expect=1e-47]} {Mouse: ENSMUSG00000042589, Cux2, cut-like homeobox 2, [RH, Score=192, Expect=2e-49]} {Dmel: FBgn0004198, ct, cut, [RH, Score=145, Expect=1e-34]} {Celegans: WBGene00000464, ceh-44, Homeobox protein cut-like ceh-44, [RH, Score=147, Expect=1e-35]} {Smed: dd_Smed_v6_13843_0_1, dd_Smed_v6_13843_0_1, [RH, Score=131, Expect=7e-31]} {RNA1509_6534} {RNA1310_2215.2} {RNA815_1260}
7. MligTC455_53266 513 10.68 Mlig455_012374

Neo: Irradiation

Age: -

Region-enriched R5: 1.494/0.00168

 CDC5L 2.417 0.705 - - 0.968 - 0.744 Mlig455_012374 {REF} {Length: 3840} {Pfam: pre-mRNA splicing factor component [PF11831.10, score=115.1]; Myb-like DNA-binding domain [PF00249.33, score=75.5]; Myb-like DNA-binding domain [PF13921.8, score=66.3]} {Human: ENSG00000096401, CDC5L, cell division cycle 5 like, [RH, Score=426, Expect=5e-138]} {Mouse: ENSMUSG00000023932, Cdc5l, cell division cycle 5-like (S. pombe), [RH, Score=425, Expect=7e-138]; ENSMUSG00000112027, Gm9045, predicted gene 9045, [RH, Score=422, Expect=8e-137]; ENSMUSG00000112814, Gm9040, predicted gene 9040, [RH, Score=422, Expect=7e-137]; ENSMUSG00000112919, Gm9049, predicted gene 9049, [RH, Score=422, Expect=8e-137]; ENSMUSG00000112216, Gm32717, predicted gene, 32717, [RH, Score=422, Expect=6e-137]; ENSMUSG00000112252, Gm32802, predicted gene, 32802, [RH, Score=422, Expect=6e-137]; ENSMUSG00000112419, Gm9044, predicted gene 9044, [RH, Score=422, Expect=7e-137]; ENSMUSG00000112495, Gm9048, predicted gene 9048, [RH, Score=418, Expect=3e-135]; ENSMUSG00000112781, Gm9046, predicted gene 9046, [RH, Score=418, Expect=3e-135]} {Dmel: FBgn0265574, Cdc5, Cell division cycle 5, [RH, Score=415, Expect=4e-134]} {Celegans: WBGene00008386, cdc-5L, Cell Division Cycle related, [RH, Score=484, Expect=6e-162]} {Smed: dd_Smed_v6_4163_0_1, dd_Smed_v6_4163_0_1, [RH, Score=308, Expect=8e-94]} {RNA1509_27632, RNA1509_41420, RNA1509_48943, RNA1509_52253, RNA1509_6311} {RNA1310_5017, RNA1509_27632, RNA1509_41420, RNA1509_48943, RNA1509_52253, RNA1509_6311} {RNA1509_27632, RNA1509_41420, RNA1509_48943, RNA1509_52253, RNA1509_6311, RNA815_11513}
8. MligTC455_16807 627 13.07 Mlig455_064067, Mlig455_064997

Neo: -

Age: -

 TRAF7 2.415 0.730 0.735 - 0.950 - -

Mlig455_064067 {REF} {Length: 2484} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=50.3]; zinc finger of C3HC4-type, RING [PF15227.8, score=26.3]} {Human: ENSG00000131653, TRAF7, TNF receptor associated factor 7, [Score=224, Expect=1e-64]} {Mouse: ENSMUSG00000052752, Traf7, TNF receptor-associated factor 7, [Score=222, Expect=2e-64]} {Dmel: FBgn0041171, ago, archipelago, [Score=60.8, Expect=2e-09]} {Celegans: WBGene00003047, lis-1, Lissencephaly-1 homolog, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7882_0_1, dd_Smed_v6_7882_0_1, [Score=164, Expect=3e-44]} {RNA1509_39146} {RNA1310_8298.2} {RNA815_8655}

Mlig455_064997 {REF} {Length: 2598} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=81.4]; zinc finger of C3HC4-type, RING [PF15227.8, score=26.1]} {Human: ENSG00000131653, TRAF7, TNF receptor associated factor 7, [RH, Score=288, Expect=1e-87]} {Mouse: ENSMUSG00000052752, Traf7, TNF receptor-associated factor 7, [RH, Score=287, Expect=4e-88]} {Dmel: FBgn0041171, ago, archipelago, [Score=95.1, Expect=6e-20]} {Celegans: WBGene00003009, lin-23, F-box/WD repeat-containing protein lin-23, [Score=83.2, Expect=2e-16]} {Smed: dd_Smed_v6_7882_0_1, dd_Smed_v6_7882_0_1, [RH, Score=228, Expect=5e-67]} {RNA1509_53263} {RNA1310_8298.2} {RNA815_12519}
9. MligTC455_46292 444 9.24 Mlig455_024938

Neo: -

Age: -

Region-enriched R5: 2.279/0.00036

 SLC17A9 1.911 - - - 0.968 0.943 - Mlig455_024938 {REF} {Length: 2751} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=154.2]} {Human: ENSG00000101194, SLC17A9, solute carrier family 17 member 9, [RH, Score=314, Expect=2e-102]} {Mouse: ENSMUSG00000023393, Slc17a9, solute carrier family 17, member 9, [RH, Score=308, Expect=7e-100]} {Dmel: FBgn0025684, MFS18, Major Facilitator Superfamily Transporter 18, [RH, Score=333, Expect=4e-110]} {Celegans: WBGene00010758, vnut-1, Vesicular NUcleotide Transporte, [RH, Score=310, Expect=8e-101]} {Smed: dd_Smed_v6_1326_0_1, dd_Smed_v6_1326_0_1, [RH, Score=414, Expect=1e-141]} {RNA1509_48544, RNA1509_7549} {RNA1310_6054.1, RNA1509_48544, RNA1509_7549} {RNA1509_48544, RNA1509_7549, RNA815_2086.1}
10. MligTC455_49171 415 8.65 Mlig455_006880

Neo: -

Age: Down-Up-Down

 LRRFIP2 1.91 - - - 0.984 0.926 - Mlig455_006880 {REF} {Length: 4024} {TRANSSPLICED} {Pfam: LRRFIP family [PF09738.11, score=108.0]} {Human: ENSG00000093167, LRRFIP2, LRR binding FLII interacting protein 2, [Score=112, Expect=5e-27]} {Mouse: ENSMUSG00000032497, Lrrfip2, leucine rich repeat (in FLII) interacting protein 2, [Score=112, Expect=3e-27]} {Dmel: FBgn0030699, CG8578, [Score=78.6, Expect=1e-15]} {Celegans: WBGene00018998, flap-1, FLi1-Associated Protein homolog, [Score=74.7, Expect=1e-14]} {Smed: dd_Smed_v6_5214_0_1, dd_Smed_v6_5214_0_1, [RH, Score=127, Expect=5e-33]} {RNA1509_10267, RNA1509_37919} {RNA1310_14942, RNA1509_10267, RNA1509_37919} {RNA1509_10267, RNA1509_37919, RNA815_6800.1}
11. MligTC455_19015 270 5.62 Mlig455_035264

Neo: -

Age: -

 1.891 - - - 0.961 0.930 - Mlig455_035264 {REF} {Length: 770} {NoTransDecoderORF} {RNA1310_96225} {RNA815_57553}
12. MligTC455_42537 539 11.23 Mlig455_054260

Neo: -

Age: -

 ASMTL 1.884 - - - 0.964 0.920 - Mlig455_054260 {REF} {Length: 2647} {Pfam: Maf-like protein [PF02545.16, score=192.7]} {Human: ENSG00000169093, ASMTL, acetylserotonin O-methyltransferase like, [RH, Score=134, Expect=9e-36]} {Dmel: FBgn0032077, CG9515, [RH, Score=117, Expect=3e-32]} {Celegans: WBGene00008316, dod-18, Downstream Of DAF-16 (Regulated by DAF-16), [RH, Score=115, Expect=1e-31]} {Smed: dd_Smed_v6_4785_0_1, dd_Smed_v6_4785_0_1, [RH, Score=140, Expect=3e-41]} {RNA1509_48718, RNA1509_54722} {RNA1310_49066.1, RNA1509_48718, RNA1509_54722} {RNA1509_48718, RNA1509_54722, RNA815_25209}
13. MligTC455_43514 599 12.48 Mlig455_008579

Neo: -

Age: -

 OSBPL9 1.884 - - - 0.930 0.954 - Mlig455_008579 {REF} {Length: 4182} {Pfam: Oxysterol-binding protein [PF01237.20, score=252.0]; PH domain [PF00169.31, score=48.5]; Pleckstrin homology domain [PF15409.8, score=30.7]; Protein of unknown function (DUF2722) [PF10846.10, score=20.4]; Pleckstrin homology domain [PF15413.8, score=19.2]} {Human: ENSG00000117859, OSBPL9, oxysterol binding protein like 9, [RH, Score=634, Expect=0.0]} {Mouse: ENSMUSG00000028559, Osbpl9, oxysterol binding protein-like 9, [RH, Score=642, Expect=0.0]} {Dmel: FBgn0033463, CG1513, [RH, Score=615, Expect=0.0]} {Celegans: WBGene00016331, obr-4, Oxysterol-binding protein, [RH, Score=458, Expect=2e-150]} {Smed: dd_Smed_v6_5947_0_1, dd_Smed_v6_5947_0_1, [RH, Score=602, Expect=0.0]} {RNA1509_43844, RNA1509_8406} {RNA1310_2180.1, RNA1509_43844, RNA1509_8406} {RNA1509_43844, RNA1509_8406, RNA815_7482.1}
14. MligTC455_47313 364 7.58 Mlig455_058672

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.435

 LUC7L 1.884 - - - 0.955 0.929 - Mlig455_058672 {REF} {Length: 2574} {Pfam: LUC7 N_terminus [PF03194.17, score=239.7]} {Human: ENSG00000007392, LUC7L, LUC7 like, [RH, Score=303, Expect=7e-99]; ENSG00000146963, LUC7L2, LUC7 like 2, pre-mRNA splicing factor, [RH, Score=293, Expect=9e-95]} {Mouse: ENSMUSG00000024188, Luc7l, Luc7-like, [RH, Score=303, Expect=8e-99]; ENSMUSG00000029823, Luc7l2, LUC7-like 2 (S. cerevisiae), [RH, Score=290, Expect=2e-94]} {Dmel: FBgn0036734, CG7564, [RH, Score=306, Expect=2e-99]} {Celegans: WBGene00015207, B0495.8, [RH, Score=161, Expect=2e-45]} {Smed: dd_Smed_v6_4536_0_4, dd_Smed_v6_4536_0_4, [RH, Score=300, Expect=3e-99]} {RNA1509_894} {RNA1310_9024.1} {RNA815_807.1}
15. MligTC455_33507 300 6.26 Mlig455_060204

Neo: -

Age: Up-Down-Up

 CEP135 1.881 - - - 0.926 0.955 - Mlig455_060204 {REF} {Length: 4056} {Human: ENSG00000174799, CEP135, centrosomal protein 135, [Score=112, Expect=2e-25]} {Mouse: ENSMUSG00000036403, Cep135, centrosomal protein 135, [Score=105, Expect=3e-23]} {Smed: dd_Smed_v6_5218_0_1, dd_Smed_v6_5218_0_1, [Score=122, Expect=2e-29]} {RNA1509_4418} {RNA1310_38678} {RNA815_51127}
16. MligTC455_22784 1148 23.93 Mlig455_002948

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.262/0.00560

 ACSF2 1.878 - - - 0.909 0.969 - Mlig455_002948 {REF} {Length: 3655} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=323.5]; AMP-binding enzyme C-terminal domain [PF13193.8, score=73.5]} {Human: ENSG00000167107, ACSF2, acyl-CoA synthetase family member 2, [Score=196, Expect=2e-54]} {Mouse: ENSMUSG00000076435, Acsf2, acyl-CoA synthetase family member 2, [Score=207, Expect=1e-58]} {Dmel: FBgn0027601, pdgy, pudgy, [Score=326, Expect=5e-104]} {Celegans: WBGene00008669, acs-14, Fatty Acid CoA Synthetase family, [Score=317, Expect=3e-101]} {Smed: dd_Smed_v6_10135_0_1, dd_Smed_v6_10135_0_1, [Score=363, Expect=5e-119]} {RNA1509_14977} {RNA1310_6662.1, RNA1509_14977} {RNA1509_14977, RNA815_3874}
17. MligTC455_32876 668 13.92 Mlig455_039686

Neo: -

Age: Down-Down-Up

 RAC1 1.876 - - 0.898 0.978 - - Mlig455_039686 {REF} {Length: 3690} {Pfam: Ras family [PF00071.24, score=163.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=71.2]; ADP-ribosylation factor family [PF00025.23, score=30.5]} {Human: ENSG00000136238, RAC1, Rac family small GTPase 1, [Score=225, Expect=1e-74]; ENSG00000169750, RAC3, Rac family small GTPase 3, [Score=219, Expect=1e-72]; ENSG00000128340, RAC2, Rac family small GTPase 2, [Score=216, Expect=2e-71]} {Mouse: ENSMUSG00000001847, Rac1, Rac family small GTPase 1, [Score=225, Expect=7e-75]; ENSMUSG00000018012, Rac3, Rac family small GTPase 3, [Score=219, Expect=9e-73]; ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [Score=214, Expect=7e-71]} {Dmel: FBgn0010333, Rac1, [Score=224, Expect=2e-74]} {Celegans: WBGene00003239, mig-2, Rac-like GTPase, [Score=221, Expect=2e-73]} {Smed: dd_Smed_v6_698_0_1, dd_Smed_v6_698_0_1, [Score=210, Expect=2e-69]} {RNA1509_28989} {RNA1310_27953} {RNA815_13447}
18. MligTC455_30555 345 7.18 Mlig455_014294

Neo: -

Age: -

 UBE2H 1.875 - - - 0.953 0.922 - Mlig455_014294 {REF} {Length: 4063} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=126.6]} {Human: ENSG00000186591, UBE2H, ubiquitin conjugating enzyme E2 H, [RH, Score=300, Expect=5e-105]} {Mouse: ENSMUSG00000039159, Ube2h, ubiquitin-conjugating enzyme E2H, [RH, Score=300, Expect=3e-105]} {Dmel: FBgn0029996, UbcE2H, Ubiquitin conjugating enzyme E2H, [RH, Score=280, Expect=3e-97]} {Celegans: WBGene00006705, ubc-8, UBiquitin Conjugating enzyme, [RH, Score=249, Expect=1e-84]} {Smed: dd_Smed_v6_4514_0_1, dd_Smed_v6_4514_0_1, [RH, Score=273, Expect=5e-95]} {RNA1509_13844, RNA1509_49595, RNA1509_7917, RNA1509_9318} {RNA1310_31599, RNA1509_13844, RNA1509_49595, RNA1509_7917, RNA1509_9318} {RNA1509_13844, RNA1509_49595, RNA1509_7917, RNA1509_9318, RNA815_15483}
19. MligTC455_48904 418 8.7 Mlig455_017114

Neo: -

Age: -

 ANKRD54 1.869 - - - 0.968 0.901 - Mlig455_017114 {REF} {Length: 1532} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=37.3]; Ankyrin repeat [PF13606.8, score=34.0]; Ankyrin repeats (many copies) [PF13637.8, score=33.4]; Ankyrin repeat [PF00023.32, score=28.5]; Ankyrin repeats (many copies) [PF13857.8, score=28.4]} {Human: ENSG00000100124, ANKRD54, ankyrin repeat domain 54, [RH, Score=75.9, Expect=2e-15]} {Mouse: ENSMUSG00000033055, Ankrd54, ankyrin repeat domain 54, [RH, Score=75.1, Expect=3e-15]} {Dmel: FBgn0036052, CG10809, [RH, Score=70.1, Expect=2e-13]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=53.1, Expect=1e-07]} {Smed: dd_Smed_v6_8330_0_1, dd_Smed_v6_8330_0_1, [Score=56.6, Expect=5e-09]} {RNA1509_30044, RNA1509_49195} {RNA1310_19754.1, RNA1509_30044, RNA1509_49195} {RNA1509_30044, RNA1509_49195, RNA815_39875}
20. MligTC455_47301 209 4.35 Mlig455_049133

Neo: -

Age: -

 ASXL2 1.868 - - - 0.958 0.910 - Mlig455_049133 {REF} {Length: 3735} {TRANSSPLICED} {Pfam: Asx homology domain [PF13919.8, score=57.7]} {Human: ENSG00000143970, ASXL2, ASXL transcriptional regulator 2, [RH, Score=82.8, Expect=1e-15]} {Mouse: ENSMUSG00000037486, Asxl2, additional sex combs like 2, transcriptional regulator, [RH, Score=78.6, Expect=6e-15]} {Smed: dd_Smed_v6_8139_0_1, dd_Smed_v6_8139_0_1, [Score=52.4, Expect=1e-06]} {RNA1509_12997} {RNA1310_6363, RNA1509_12997} {RNA1509_12997, RNA815_24627.1}
21. MligTC455_35348 421 8.76 Mlig455_048718

Neo: Germline

Age: Up-Up-Down

 1.865 - - 0.907 0.958 - - Mlig455_048718 {REF} {Length: 4867} {TRANSSPLICED} {Mouse: ENSMUSG00000022957, Itsn1, intersectin 1 (SH3 domain protein 1A), [Score=52.0, Expect=5e-06]} {RNA1509_24706, RNA1509_51170} {RNA1310_10906, RNA1509_24706} {RNA1509_24706, RNA815_6370.1}
22. MligTC455_20770 1008 21.01 Mlig455_053224, Mlig455_065048

Neo: -

Age: -

 ARHGAP39 1.862 - - 0.890 0.972 - -

Mlig455_053224 {REF} {Length: 5071} {Pfam: MyTH4 domain [PF00784.19, score=97.8]; RhoGAP domain [PF00620.29, score=64.1]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=22.9]} {Human: ENSG00000147799, ARHGAP39, Rho GTPase activating protein 39, [RH, Score=305, Expect=4e-89]} {Mouse: ENSMUSG00000033697, Arhgap39, Rho GTPase activating protein 39, [RH, Score=302, Expect=4e-88]} {Dmel: FBgn0038853, RhoGAP93B, Rho GTPase activating protein at 93B, [RH, Score=259, Expect=2e-72]} {Celegans: WBGene00022365, Y92H12BL.4, [RH, Score=142, Expect=1e-36]} {Smed: dd_Smed_v6_5836_0_1, dd_Smed_v6_5836_0_1, [RH, Score=214, Expect=2e-59]} {RNA1509_20743, RNA1509_37920, RNA1509_50847} {RNA1310_6549.1, RNA1509_20743, RNA1509_37920, RNA1509_50847} {RNA1509_20743, RNA1509_37920, RNA1509_50847, RNA815_6801}

Mlig455_065048 {REF} {Length: 5179} {Pfam: MyTH4 domain [PF00784.19, score=97.8]; RhoGAP domain [PF00620.29, score=65.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=22.9]} {Human: ENSG00000147799, ARHGAP39, Rho GTPase activating protein 39, [RH, Score=307, Expect=1e-89]} {Mouse: ENSMUSG00000033697, Arhgap39, Rho GTPase activating protein 39, [RH, Score=304, Expect=1e-88]} {Dmel: FBgn0038853, RhoGAP93B, Rho GTPase activating protein at 93B, [RH, Score=260, Expect=8e-73]} {Celegans: WBGene00022365, Y92H12BL.4, [RH, Score=144, Expect=4e-37]} {Smed: dd_Smed_v6_5836_0_1, dd_Smed_v6_5836_0_1, [RH, Score=214, Expect=2e-59]} {RNA1509_20743, RNA1509_53778} {RNA1310_6549.1, RNA1509_53778} {RNA1509_53778, RNA815_6801}
23. MligTC455_44425 460 9.58 Mlig455_041704

Neo: -

Age: -

 IPO11 1.862 - - - 0.961 0.901 - Mlig455_041704 {REF} {Length: 4130} {TRANSSPLICED} {Pfam: Importin-beta N-terminal domain [PF03810.21, score=40.5]} {Human: ENSG00000086200, IPO11, importin 11, [RH, Score=132, Expect=1e-30]} {Mouse: ENSMUSG00000042590, Ipo11, importin 11, [RH, Score=132, Expect=5e-31]} {Dmel: FBgn0284254, Impbeta11, Importin beta11, [RH, Score=96.7, Expect=5e-20]} {RNA1509_12338} {RNA1310_4949.1} {RNA815_1982}
24. MligTC455_33954 280 5.84 Mlig455_058149

Neo: -

Age: -

 1.853 - - - 0.978 0.875 - Mlig455_058149 {REF} {Length: 3221} {RNA1310_32323} {RNA815_59403}
25. MligTC455_20663 552 11.51 Mlig455_031298

Neo: Neoblast, stringent

Age: -

Region-enriched R5: 1.075/0.02847

 HELLS 1.851 - - - 0.963 0.888 - Mlig455_031298 {REF} {Length: 5758} {TRANSSPLICED} {Pfam: SNF2-related domain [PF00176.25, score=210.0]; Helicase conserved C-terminal domain [PF00271.33, score=64.4]; Type III restriction enzyme, res subunit [PF04851.17, score=24.2]; Class II histone deacetylase complex subunits 2 and 3 [PF11496.10, score=21.7]} {Human: ENSG00000119969, HELLS, helicase, lymphoid specific, [RH, Score=598, Expect=0.0]} {Mouse: ENSMUSG00000025001, Hells, helicase, lymphoid specific, [Score=599, Expect=0.0]} {Dmel: FBgn0000212, brm, brahma, [Score=244, Expect=1e-66]} {Celegans: WBGene00004204, swsn-4, SWI/SNF nucleosome remodeling complex component; SWI2/SNF2-like protein, [Score=240, Expect=3e-65]} {Smed: dd_Smed_v6_7560_0_1, dd_Smed_v6_7560_0_1, [Score=300, Expect=2e-89]} {RNA1509_22520, RNA1509_23242} {RNA1310_5705, RNA1509_22520, RNA1509_23242} {RNA1509_22520, RNA1509_23242, RNA815_1136}
26. MligTC455_52561 506 10.55 Mlig455_034297

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.318

 ARIH1 1.851 - - 0.891 0.960 - - Mlig455_034297 {REF} {Length: 4225} {TRANSSPLICED} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=60.4]; Ariadne domain [PF19422.1, score=47.5]} {Human: ENSG00000166233, ARIH1, ariadne RBR E3 ubiquitin protein ligase 1, [RH, Score=437, Expect=1e-147]} {Mouse: ENSMUSG00000025234, Arih1, ariadne RBR E3 ubiquitin protein ligase 1, [RH, Score=437, Expect=6e-148]} {Dmel: FBgn0017418, ari-1, ariadne 1, [RH, Score=444, Expect=2e-151]} {Celegans: WBGene00016158, ari-1, ARI (Ubiquitin ligase Ariadne) homolog, [RH, Score=405, Expect=2e-136]} {Smed: dd_Smed_v6_4224_0_1, dd_Smed_v6_4224_0_1, [RH, Score=454, Expect=2e-155]} {RNA1509_24929, RNA1509_9820} {RNA1310_13675, RNA1509_24929, RNA1509_9820} {RNA1509_24929, RNA1509_9820, RNA815_11154}
27. MligTC455_52560 503 10.49 Mlig455_034260

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.847

 ARIH1 1.85 - - 0.893 0.957 - - Mlig455_034260 {REF} {Length: 5125} {TRANSSPLICED} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=60.4]; Ariadne domain [PF19422.1, score=47.6]} {Human: ENSG00000166233, ARIH1, ariadne RBR E3 ubiquitin protein ligase 1, [RH, Score=436, Expect=3e-147]} {Mouse: ENSMUSG00000025234, Arih1, ariadne RBR E3 ubiquitin protein ligase 1, [RH, Score=436, Expect=2e-147]} {Dmel: FBgn0017418, ari-1, ariadne 1, [RH, Score=442, Expect=5e-151]} {Celegans: WBGene00016158, ari-1, ARI (Ubiquitin ligase Ariadne) homolog, [RH, Score=407, Expect=3e-137]} {Smed: dd_Smed_v6_4224_0_1, dd_Smed_v6_4224_0_1, [RH, Score=454, Expect=3e-155]} {RNA1509_23245, RNA1509_46197, RNA1509_9820} {RNA1310_13675, RNA1509_23245, RNA1509_46197} {RNA1509_23245, RNA1509_46197, RNA815_11154}
28. MligTC455_17869 337 7.02 Mlig455_067725

Neo: Int S/G2/M

Age: -

 1.848 - - - 0.969 0.879 - Mlig455_067725 {REF} {Length: 2651} {TRANSSPLICED} {RNA1509_51335} {RNA1310_20317, RNA1509_51335} {RNA1509_51335, RNA815_19485}
29. MligTC455_43180 135 2.81 Mlig455_053081

Neo: -

Age: -

 1.843 - - 0.886 0.957 - - Mlig455_053081 {REF} {Length: 965} {NoTransDecoderORF} {RNA1509_53340} {RNA1310_33099, RNA1509_53340}
30. MligTC455_00831 642 13.37 Mlig455_016457, Mlig455_016523

Neo: -

Age: logFC(26M/2M)=0.506

 LGR5 1.842 - - 0.886 0.956 - -

Mlig455_016457 {REF} {Length: 4347} {Pfam: Leucine rich repeat [PF13855.8, score=86.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=45.8]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=40.5]} {Human: ENSG00000139292, LGR5, leucine rich repeat containing G protein-coupled receptor 5, [Score=58.5, Expect=7e-08]; ENSG00000145147, SLIT2, slit guidance ligand 2, [Score=57.0, Expect=2e-07]} {Mouse: ENSMUSG00000020140, Lgr5, leucine rich repeat containing G protein coupled receptor 5, [Score=59.7, Expect=2e-08]} {Dmel: FBgn0267435, chp, chaoptin, [Score=67.0, Expect=8e-11]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=55.8, Expect=2e-07]} {RNA1509_8817} {RNA1310_2409} {RNA815_590.1}

Mlig455_016523 {REF} {Length: 3360} {Pfam: Leucine rich repeat [PF13855.8, score=41.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=39.1]} {RNA1509_8817} {RNA1310_22547} {RNA815_590.1}
31. MligTC455_21833 1002 20.87 Mlig455_026895, Mlig455_030758

Neo: Irradiation

Age: logFC(26M/2M)=0.192

 IPO5 1.841 - - 0.890 0.951 - -

Mlig455_026895 {REF} {Length: 6193} {Pfam: Importin repeat 6 [PF18829.3, score=95.5]; Importin repeat [PF18808.3, score=85.2]; HEAT repeats [PF13646.8, score=56.5]; HEAT repeat [PF02985.24, score=53.3]; HEAT-like repeat [PF13513.8, score=48.4]; Vacuolar 14 Fab1-binding region [PF12755.9, score=45.7]; Importin repeat [PF18816.3, score=27.2]; CLASP N terminal [PF12348.10, score=23.1]; Dos2-interacting transcription regulator of RNA-Pol-II [PF14500.8, score=22.0]} {Human: ENSG00000065150, IPO5, importin 5, [RH, Score=1080, Expect=0.0]} {Mouse: ENSMUSG00000030662, Ipo5, importin 5, [RH, Score=1076, Expect=0.0]} {Dmel: FBgn0087013, Karybeta3, Karyopherin beta 3, [RH, Score=1053, Expect=0.0]} {Celegans: WBGene00002077, imb-3, IMportin Beta family, [RH, Score=615, Expect=0.0]} {Smed: dd_Smed_v6_1262_0_1, dd_Smed_v6_1262_0_1, [RH, Score=865, Expect=0.0]} {RNA1509_28178, RNA1509_30106, RNA1509_46827, RNA1509_55560, RNA1509_879} {RNA1310_2919.1, RNA1509_28178, RNA1509_30106, RNA1509_46827, RNA1509_55560} {RNA1509_28178, RNA1509_30106, RNA1509_46827, RNA1509_55560, RNA815_887}

Mlig455_030758 {REF} {Length: 5608} {Pfam: Importin repeat 6 [PF18829.3, score=95.3]; Importin repeat [PF18808.3, score=85.2]; HEAT repeats [PF13646.8, score=55.2]; HEAT repeat [PF02985.24, score=53.2]; HEAT-like repeat [PF13513.8, score=48.4]; Vacuolar 14 Fab1-binding region [PF12755.9, score=45.7]; Importin repeat [PF18816.3, score=25.6]; CLASP N terminal [PF12348.10, score=22.8]; Dos2-interacting transcription regulator of RNA-Pol-II [PF14500.8, score=21.6]} {Human: ENSG00000065150, IPO5, importin 5, [RH, Score=1081, Expect=0.0]} {Mouse: ENSMUSG00000030662, Ipo5, importin 5, [RH, Score=1078, Expect=0.0]} {Dmel: FBgn0087013, Karybeta3, Karyopherin beta 3, [RH, Score=1055, Expect=0.0]} {Celegans: WBGene00002077, imb-3, IMportin Beta family, [RH, Score=616, Expect=0.0]} {Smed: dd_Smed_v6_1262_0_1, dd_Smed_v6_1262_0_1, [RH, Score=864, Expect=0.0]} {RNA1509_13195, RNA1509_19831, RNA1509_23099, RNA1509_37858, RNA1509_879} {RNA1310_2919.1, RNA1509_13195, RNA1509_19831, RNA1509_23099, RNA1509_37858, RNA1509_879} {RNA1509_13195, RNA1509_19831, RNA1509_23099, RNA1509_37858, RNA1509_879, RNA815_887}
32. MligTC455_33785 1166 24.28 Mlig455_046906

Neo: -

Age: -

 LETM1 1.841 - - - 0.978 - 0.863 Mlig455_046906 {REF} {Length: 4438} {Pfam: LETM1-like protein [PF07766.15, score=292.9]} {Human: ENSG00000168924, LETM1, leucine zipper and EF-hand containing transmembrane protein 1, [RH, Score=333, Expect=2e-101]} {Mouse: ENSMUSG00000005299, Letm1, leucine zipper-EF-hand containing transmembrane protein 1, [RH, Score=331, Expect=7e-101]} {Dmel: FBgn0284252, Letm1, Leucine zipper and EF-hand containing transmembrane protein 1, [RH, Score=310, Expect=7e-91]} {Celegans: WBGene00010279, letm-1, LETM1 (Leucine zipper, EF-hand, TransMembrane mitochondrial protein) homolog, [RH, Score=330, Expect=2e-100]} {Smed: dd_Smed_v6_4348_0_1, dd_Smed_v6_4348_0_1, [RH, Score=378, Expect=4e-119]} {RNA1509_19480, RNA1509_28848, RNA1509_3368, RNA1509_52640} {RNA1310_3687.1, RNA1509_19480, RNA1509_28848, RNA1509_52640} {RNA1509_19480, RNA1509_28848, RNA1509_52640, RNA815_1948}
33. MligTC455_37798 389 8.1 Mlig455_060511

Neo: -

Age: Down-Up-Down

 1.837 - - 0.854 0.983 - - Mlig455_060511 {REF} {Length: 3180} {RNA1509_15445, RNA1509_31771} {RNA1310_35217, RNA1509_15445, RNA1509_31771} {RNA1509_15445, RNA1509_31771, RNA815_22565}
34. MligTC455_17750 499 10.4 Mlig455_053518, Mlig455_061005

Neo: -

Age: -

 1.836 - - 0.878 0.958 - -

Mlig455_053518 {REF} {Length: 2921} {RNA1509_50148} {RNA1310_33299} {RNA815_10857.1}

Mlig455_061005 {REF} {Length: 1405} {RNA1509_50148} {RNA1310_33299, RNA1509_50148} {RNA1509_50148, RNA815_10857.1}
35. MligTC455_27453 315 6.56 Mlig455_066188

Neo: -

Age: Up-Down-Down

 NCSTN 1.833 - - - - 0.975 0.858 Mlig455_066188 {REF} {Length: 7384} {TRANSSPLICED} {Pfam: Nicastrin small lobe [PF18266.3, score=91.3]; Nicastrin [PF05450.17, score=91.2]} {Human: ENSG00000162736, NCSTN, nicastrin, [RH, Score=163, Expect=1e-41]} {Mouse: ENSMUSG00000003458, Ncstn, nicastrin, [RH, Score=152, Expect=3e-38]} {Dmel: FBgn0039234, Nct, Nicastrin, [RH, Score=145, Expect=4e-36]} {Celegans: WBGene00000148, aph-2, Nicastrin, [RH, Score=112, Expect=3e-25]} {Smed: dd_Smed_v6_1685_0_1, dd_Smed_v6_1685_0_1, [RH, Score=154, Expect=4e-39]} {RNA1509_56086, RNA1509_5633} {RNA1310_6134, RNA1509_56086} {RNA1509_56086, RNA815_3195.1}
36. MligTC455_41157 316 6.58 Mlig455_014919

Neo: -

Age: -

Region-enriched R5: 2.518/0.03402

 1.818 - - - 0.972 0.846 - Mlig455_014919 {REF} {Length: 209} {NoTransDecoderORF} {RNA1509_23742} {RNA1310_15250} {RNA815_6483.2}
37. Mlig999007.1 1.813 - - 0.857 0.956 - -
38. MligTC455_45502 324 6.75 Mlig455_057191

Neo: -

Age: -

 USP54 1.813 - - - 0.956 0.857 - Mlig455_057191 {REF} {Length: 5240} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=56.2]} {Human: ENSG00000166348, USP54, ubiquitin specific peptidase 54, [RH, Score=280, Expect=7e-79]} {Mouse: ENSMUSG00000034235, Usp54, ubiquitin specific peptidase 54, [RH, Score=279, Expect=7e-79]} {Dmel: FBgn0000542, ec, echinus, [RH, Score=236, Expect=1e-64]} {RNA1509_14635, RNA1509_38398} {RNA1310_8155.1, RNA1509_14635, RNA1509_38398} {RNA1509_14635, RNA1509_38398, RNA815_4435}
39. MligTC455_44752 734 15.3 Mlig455_006900

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.321

 IER3IP1 1.81 - - - 0.961 0.849 - Mlig455_006900 {REF} {Length: 1800} {TRANSSPLICED} {Pfam: Yos1-like [PF08571.12, score=96.1]} {Human: ENSG00000134049, IER3IP1, immediate early response 3 interacting protein 1, [RH, Score=82.0, Expect=8e-22]; ENSG00000267228, AC012254.2, novel transcript, [RH, Score=82.0, Expect=8e-22]} {Mouse: ENSMUSG00000090000, Ier3ip1, immediate early response 3 interacting protein 1, [RH, Score=81.6, Expect=8e-22]} {Dmel: FBgn0052069, CG32069, [RH, Score=88.2, Expect=1e-24]} {Celegans: WBGene00012371, W09G3.8, [RH, Score=63.9, Expect=4e-15]} {Smed: dd_Smed_v6_7782_0_1, dd_Smed_v6_7782_0_1, [RH, Score=84.3, Expect=3e-23]} {RNA1509_14620, RNA1509_28131, RNA1509_29591} {RNA1310_34670.1, RNA1509_14620, RNA1509_28131, RNA1509_29591} {RNA1509_14620, RNA1509_28131, RNA1509_29591, RNA815_29229}
40. MligTC455_44753 727 15.15 Mlig455_017913

Neo: -

Age: -

 IER3IP1 1.81 - - - 0.961 0.849 - Mlig455_017913 {REF} {Length: 1437} {TRANSSPLICED} {Pfam: Yos1-like [PF08571.12, score=96.1]} {Human: ENSG00000134049, IER3IP1, immediate early response 3 interacting protein 1, [RH, Score=82.0, Expect=8e-22]; ENSG00000267228, AC012254.2, novel transcript, [RH, Score=82.0, Expect=8e-22]} {Mouse: ENSMUSG00000090000, Ier3ip1, immediate early response 3 interacting protein 1, [RH, Score=81.6, Expect=8e-22]} {Dmel: FBgn0052069, CG32069, [RH, Score=88.2, Expect=1e-24]} {Celegans: WBGene00012371, W09G3.8, [RH, Score=63.9, Expect=4e-15]} {Smed: dd_Smed_v6_7782_0_1, dd_Smed_v6_7782_0_1, [RH, Score=84.3, Expect=3e-23]} {RNA1509_28131, RNA1509_42004} {RNA1310_34670.1, RNA1509_42004} {RNA1509_42004, RNA815_29229}
41. Mlig999008.1 1.809 - - - 0.965 0.844 -
42. MligTC455_39241 166 3.45 Mlig455_041934

Neo: Irradiation

Age: -

 NEK2 1.808 - - - 0.951 0.857 - Mlig455_041934 {REF} {Length: 2141} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=171.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=113.2]; Kinase-like [PF14531.8, score=26.0]; ABC1 atypical kinase-like domain [PF03109.18, score=21.0]} {Human: ENSG00000117650, NEK2, NIMA related kinase 2, [Score=287, Expect=5e-92]} {Mouse: ENSMUSG00000110797, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=278, Expect=1e-88]; ENSMUSG00000026622, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=278, Expect=1e-88]} {Dmel: FBgn0029970, Nek2, [Score=227, Expect=2e-66]} {Celegans: WBGene00008956, nekl-3, Serine/threonine-protein kinase nekl-3, [Score=161, Expect=9e-46]} {Smed: dd_Smed_v6_8347_0_2, dd_Smed_v6_8347_0_2, [Score=162, Expect=3e-46]} {RNA1509_56527} {RNA1310_29373} {RNA815_3391.1}
43. MligTC455_33882 644 13.41 Mlig455_055943

Neo: -

Age: -

 STX12 1.796 0.844 - - 0.952 - - Mlig455_055943 {REF} {Length: 3583} {TRANSSPLICED} {Pfam: SNARE domain [PF05739.21, score=62.2]; Syntaxin-like protein [PF14523.8, score=58.6]} {Human: ENSG00000117758, STX12, syntaxin 12, [Score=132, Expect=1e-36]} {Mouse: ENSMUSG00000019998, Stx7, syntaxin 7, [Score=126, Expect=1e-34]; ENSMUSG00000028879, Stx12, syntaxin 12, [Score=125, Expect=2e-34]} {Dmel: FBgn0267849, Syx7, Syntaxin 7, [Score=108, Expect=8e-28]} {Celegans: WBGene00009478, syx-7, SYntaXin, [Score=95.9, Expect=2e-23]} {Smed: dd_Smed_v6_4152_0_1, dd_Smed_v6_4152_0_1, [Score=107, Expect=4e-28]} {RNA1509_15629, RNA1509_38250, RNA1509_55825} {RNA1310_27494, RNA1509_15629, RNA1509_55825} {RNA1509_15629, RNA1509_55825, RNA815_14197}
44. MligTC455_20772 671 13.98 Mlig455_007828

Neo: -

Age: -

 1.793 - - - 0.963 0.830 - Mlig455_007828 {REF} {Length: 2327} {TRANSSPLICED} {Pfam: Ezrin/radixin/moesin family [PF00769.21, score=25.0]} {RNA1509_16297, RNA1509_54141} {RNA1310_16574.1, RNA1509_16297, RNA1509_54141} {RNA1509_16297, RNA1509_54141, RNA815_19017}
45. MligTC455_17489 357 7.44 Mlig455_057590

Neo: -

Age: Up-Down-Down

 ARHGEF7 1.782 - - 0.828 0.954 - - Mlig455_057590 {REF} {Length: 5348} {TRANSSPLICED} {Pfam: Variant SH3 domain [PF14604.8, score=57.8]; SH3 domain [PF00018.30, score=53.0]; Variant SH3 domain [PF07653.19, score=49.3]; RhoGEF domain [PF00621.22, score=34.9]; Unstructured region two on RhoGEF 6 and 7 [PF16614.7, score=27.8]} {Human: ENSG00000102606, ARHGEF7, Rho guanine nucleotide exchange factor 7, [RH, Score=169, Expect=7e-44]} {Mouse: ENSMUSG00000031511, Arhgef7, Rho guanine nucleotide exchange factor (GEF7), [RH, Score=164, Expect=2e-42]} {Dmel: FBgn0015803, RtGEF, Rho-type guanine nucleotide exchange factor, [RH, Score=140, Expect=5e-34]} {Celegans: WBGene00010776, pix-1, PIX (PAK (p21-activated kinase) Interacting eXchange factor) homolog, [Score=103, Expect=4e-23]} {Smed: dd_Smed_v6_4423_0_1, dd_Smed_v6_4423_0_1, [RH, Score=157, Expect=2e-40]} {RNA1509_19459} {RNA1310_3287, RNA1509_19459} {RNA1509_19459, RNA815_13921}
46. MligTC455_27560 794 16.55 Mlig455_058229

Neo: -

Age: -

 1.782 - - - 0.950 0.832 - Mlig455_058229 {REF} {Length: 190} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_5625} {RNA1310_26303.1} {RNA815_881.1}
47. MligTC455_41326 407 8.48 Mlig455_011060

Neo: -

Age: -

 KCNA2 1.774 - - 0.816 0.958 - - Mlig455_011060 {REF} {Length: 6096} {Pfam: Ion transport protein [PF00520.33, score=161.6]; BTB/POZ domain [PF02214.24, score=99.2]; Ion channel [PF07885.18, score=50.3]} {Human: ENSG00000177301, KCNA2, potassium voltage-gated channel subfamily A member 2, [RH, Score=620, Expect=0.0]; ENSG00000111262, KCNA1, potassium voltage-gated channel subfamily A member 1, [RH, Score=617, Expect=0.0]; ENSG00000177272, KCNA3, potassium voltage-gated channel subfamily A member 3, [RH, Score=611, Expect=0.0]} {Mouse: ENSMUSG00000040724, Kcna2, potassium voltage-gated channel, shaker-related subfamily, member 2, [RH, Score=619, Expect=0.0]; ENSMUSG00000047976, Kcna1, potassium voltage-gated channel, shaker-related subfamily, member 1, [RH, Score=617, Expect=0.0]; ENSMUSG00000047959, Kcna3, potassium voltage-gated channel, shaker-related subfamily, member 3, [RH, Score=607, Expect=0.0]} {Dmel: FBgn0003380, Sh, Shaker, [RH, Score=643, Expect=0.0]} {Celegans: WBGene00014261, shk-1, Potassium voltage-gated channel protein shk-1, [RH, Score=383, Expect=6e-127]} {Smed: dd_Smed_v6_15425_0_1, dd_Smed_v6_15425_0_1, [RH, Score=715, Expect=0.0]} {RNA1509_19798} {RNA1310_8877, RNA1509_19798} {RNA1509_19798, RNA815_8082.1}
48. MligTC455_47881 984 20.49 Mlig455_003664

Neo: -

Age: -

 1.764 - - 0.952 0.812 - - Mlig455_003664 {REF} {Length: 1690} {TRANSSPLICED} {RNA1509_15949} {RNA1310_16621.2, RNA1509_15949} {RNA1509_15949, RNA815_9106.1}
49. MligTC455_47289 1718 35.8 Mlig455_028690, Mlig455_028713

Neo: Neoblast

Age: logFC(26M/2M)=0.203

 SRSF1 1.76 - - - 0.953 0.807 -

Mlig455_028690 {REF} {Length: 2107} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=64.6]} {Human: ENSG00000136450, SRSF1, serine and arginine rich splicing factor 1, [Score=121, Expect=3e-33]} {Mouse: ENSMUSG00000098301, Srsf1, serine/arginine-rich splicing factor 1, [Score=121, Expect=2e-33]; ENSMUSG00000018379, Srsf1, serine/arginine-rich splicing factor 1, [Score=121, Expect=2e-33]} {Dmel: FBgn0283477, SF2, Splicing factor 2, [Score=128, Expect=4e-36]} {Celegans: WBGene00004700, rsp-3, Probable splicing factor, arginine/serine-rich 3, [Score=114, Expect=9e-31]} {Smed: dd_Smed_v6_3866_0_10, dd_Smed_v6_3866_0_10, [Score=130, Expect=1e-37]} {RNA1509_15981} {RNA1310_13088.1} {RNA815_4976.1}

Mlig455_028713 {REF} {Length: 2334} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=105.6]; RNA binding motif [PF08777.13, score=24.5]; Nup53/35/40-type RNA recognition motif [PF14605.8, score=19.8]} {Human: ENSG00000136450, SRSF1, serine and arginine rich splicing factor 1, [RH, Score=206, Expect=6e-66]} {Mouse: ENSMUSG00000018379, Srsf1, serine/arginine-rich splicing factor 1, [RH, Score=206, Expect=4e-66]; ENSMUSG00000098301, Srsf1, serine/arginine-rich splicing factor 1, [RH, Score=206, Expect=4e-66]} {Dmel: FBgn0283477, SF2, Splicing factor 2, [RH, Score=213, Expect=7e-69]} {Celegans: WBGene00004700, rsp-3, Probable splicing factor, arginine/serine-rich 3, [RH, Score=180, Expect=4e-56]} {Smed: dd_Smed_v6_3866_0_10, dd_Smed_v6_3866_0_10, [RH, Score=223, Expect=2e-73]} {RNA1509_15981, RNA1509_25451, RNA1509_29334, RNA1509_42978} {RNA1310_13088.1, RNA1509_25451, RNA1509_29334, RNA1509_42978} {RNA1509_25451, RNA1509_29334, RNA1509_42978, RNA815_4976.1}
50. MligTC455_33195 836 17.42 Mlig455_000057, Mlig455_063727

Neo: -

Age: logFC(26M/2M)=0.406

 FIP1L1 1.755 - - - 0.963 0.792 -

Mlig455_000057 {REF} {Length: 2122} {TRANSSPLICED} {Pfam: Fip1 motif [PF05182.15, score=71.4]} {Human: ENSG00000145216, FIP1L1, factor interacting with PAPOLA and CPSF1, [RH, Score=94.4, Expect=7e-20]} {Mouse: ENSMUSG00000029227, Fip1l1, FIP1 like 1 (S. cerevisiae), [RH, Score=92.4, Expect=2e-19]} {Dmel: FBgn0037255, Fip1, Factor interacting with poly(A) polymerase 1, [RH, Score=90.9, Expect=8e-19]} {Celegans: WBGene00017988, fipp-1, Factor Interacting with Poly(A) Polymerase, [RH, Score=84.0, Expect=7e-17]} {Smed: dd_Smed_v6_2560_0_1, dd_Smed_v6_2560_0_1, [RH, Score=114, Expect=4e-27]} {RNA1509_14985, RNA1509_48324} {RNA1310_12515, RNA1509_48324} {RNA1509_48324, RNA815_32908}

Mlig455_063727 {REF} {Length: 3480} {TRANSSPLICED} {Pfam: Fip1 motif [PF05182.15, score=72.1]} {Human: ENSG00000145216, FIP1L1, factor interacting with PAPOLA and CPSF1, [RH, Score=88.6, Expect=5e-18]} {Mouse: ENSMUSG00000029227, Fip1l1, FIP1 like 1 (S. cerevisiae), [RH, Score=89.4, Expect=3e-18]} {Dmel: FBgn0037255, Fip1, Factor interacting with poly(A) polymerase 1, [RH, Score=89.7, Expect=2e-18]} {Celegans: WBGene00017988, fipp-1, Factor Interacting with Poly(A) Polymerase, [RH, Score=86.7, Expect=1e-17]} {Smed: dd_Smed_v6_2560_0_1, dd_Smed_v6_2560_0_1, [RH, Score=111, Expect=4e-26]} {RNA1509_14985} {RNA1310_12515, RNA1509_14985} {RNA1509_14985, RNA815_32908}
51. MligTC455_34286 641 13.35 Mlig455_057009

Neo: -

Age: -

 1.755 - - 0.778 0.977 - - Mlig455_057009 {REF} {Length: 1242} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_35262} {RNA1310_20897, RNA1509_35262} {RNA1509_35262, RNA815_22915.1}
52. MligTC455_17185 1203 25.06 Mlig455_043379, Mlig455_043547

Neo: -

Age: -

Region-enriched R3: 2.698/0.00014
Region-enriched R6: 2.303/0.00650

 1.753 - - - 0.950 0.803 -

Mlig455_043379 {REF} {Length: 1593} {Pfam: YhhN family [PF07947.16, score=80.0]} {Dmel: FBgn0039681, CG7582, [Score=52.4, Expect=6e-08]} {Smed: dd_Smed_v6_11970_0_1, dd_Smed_v6_11970_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_28364} {RNA1310_11695.1} {RNA815_14610}

Mlig455_043547 {REF} {Length: 2226} {Pfam: YhhN family [PF07947.16, score=80.0]} {Dmel: FBgn0039681, CG7582, [Score=52.4, Expect=6e-08]} {Smed: dd_Smed_v6_11970_0_1, dd_Smed_v6_11970_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_28364, RNA1509_37355} {RNA1310_11695.1, RNA1509_37355} {RNA1509_37355, RNA815_14610}
53. MligTC455_49861 777 16.18 Mlig455_008364

Neo: Irradiation

Age: -

 BRD9 1.752 - - - 0.972 0.780 - Mlig455_008364 {REF} {Length: 2122} {TRANSSPLICED} {Pfam: Bromodomain [PF00439.27, score=88.2]; Domain of unknown function (DUF3512) [PF12024.10, score=29.7]} {Human: ENSG00000028310, BRD9, bromodomain containing 9, [RH, Score=119, Expect=6e-30]} {Mouse: ENSMUSG00000057649, Brd9, bromodomain containing 9, [RH, Score=120, Expect=3e-29]} {Dmel: FBgn0031947, CG7154, [RH, Score=104, Expect=5e-23]} {Celegans: WBGene00007256, swsn-9, SWI/SNF nucleosome remodeling complex component, [RH, Score=75.5, Expect=5e-14]} {Smed: dd_Smed_v6_4413_0_1, dd_Smed_v6_4413_0_1, [RH, Score=102, Expect=4e-23]} {RNA1509_35248, RNA1509_43301, RNA1509_56520} {RNA1310_7891.1, RNA1509_35248, RNA1509_43301, RNA1509_56520} {RNA1509_35248, RNA1509_43301, RNA1509_56520, RNA815_23148}
54. MligTC455_45514 535 11.15 Mlig455_039382, Mlig455_039389

Neo: -

Age: -

Region-enriched R5: 2.510/0.00057

 EPHX4 1.748 - - - 0.953 0.795 -

Mlig455_039382 {REF} {Length: 1895} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=81.6]; Alpha/beta hydrolase family [PF12697.9, score=80.2]; Serine aminopeptidase, S33 [PF12146.10, score=41.0]} {Human: ENSG00000172031, EPHX4, epoxide hydrolase 4, [Score=228, Expect=2e-71]} {Mouse: ENSMUSG00000033805, Ephx4, epoxide hydrolase 4, [RH, Score=238, Expect=1e-75]} {Dmel: FBgn0035951, CG5068, [Score=47.8, Expect=9e-06]} {Celegans: WBGene00010628, ceeh-2, Epoxide hydrolase 2, [RH, Score=216, Expect=1e-67]} {Smed: dd_Smed_v6_2011_0_1, dd_Smed_v6_2011_0_1, [RH, Score=247, Expect=2e-79]} {RNA1509_44576} {RNA1310_24565} {RNA815_17934}

Mlig455_039389 {REF} {Length: 2224} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=81.6]; Alpha/beta hydrolase family [PF12697.9, score=80.6]; Serine aminopeptidase, S33 [PF12146.10, score=41.0]} {Human: ENSG00000172031, EPHX4, epoxide hydrolase 4, [Score=227, Expect=3e-71]} {Mouse: ENSMUSG00000033805, Ephx4, epoxide hydrolase 4, [RH, Score=238, Expect=2e-75]} {Dmel: FBgn0035951, CG5068, [Score=47.8, Expect=9e-06]} {Celegans: WBGene00010628, ceeh-2, Epoxide hydrolase 2, [RH, Score=216, Expect=3e-67]} {Smed: dd_Smed_v6_2011_0_1, dd_Smed_v6_2011_0_1, [RH, Score=246, Expect=3e-79]} {RNA1509_44576} {RNA1310_24565} {RNA815_17934}
55. MligTC455_17189 979 20.39 Mlig455_060262

Neo: -

Age: Down-Down-Up

 MCRS1 1.746 - - - 0.968 - 0.778 Mlig455_060262 {REF} {Length: 2447} {TRANSSPLICED} {Pfam: N-terminal region of micro-spherule protein [PF13325.8, score=88.1]} {Human: ENSG00000187778, MCRS1, microspherule protein 1, [Score=90.5, Expect=3e-19]} {Mouse: ENSMUSG00000037570, Mcrs1, microspherule protein 1, [Score=93.2, Expect=2e-20]} {Dmel: FBgn0263832, Rcd5, Reduction in Cnn dots 5, [Score=80.1, Expect=4e-16]} {Celegans: WBGene00018026, F35A5.4, [Score=48.9, Expect=4e-06]} {Smed: dd_Smed_v6_4102_0_1, dd_Smed_v6_4102_0_1, [Score=77.8, Expect=1e-15]} {RNA1509_8483} {RNA1310_19335} {RNA815_6260}
56. MligTC455_41814 525 10.93 Mlig455_067134

Neo: Irradiation

Age: -

 PPP1R2 1.743 - - 0.777 0.966 - - Mlig455_067134 {REF} {Length: 2837} {TRANSSPLICED} {Pfam: Protein phosphatase inhibitor 2 (IPP-2) [PF04979.16, score=107.7]} {Human: ENSG00000184203, PPP1R2, protein phosphatase 1 regulatory inhibitor subunit 2, [RH, Score=101, Expect=3e-26]} {Mouse: ENSMUSG00000047714, Ppp1r2, protein phosphatase 1, regulatory inhibitor subunit 2, [RH, Score=91.3, Expect=1e-22]} {Dmel: FBgn0028429, I-2, Inhibitor-2, [RH, Score=73.6, Expect=4e-16]} {Celegans: WBGene00021312, szy-2, Suppressor of ZYg-1, [RH, Score=92.8, Expect=2e-23]} {Smed: dd_Smed_v6_5135_0_1, dd_Smed_v6_5135_0_1, [RH, Score=72.4, Expect=4e-16]} {RNA1509_24723, RNA1509_51446, RNA1509_56353} {RNA1310_40287, RNA1509_24723, RNA1509_51446, RNA1509_56353} {RNA1509_24723, RNA1509_51446, RNA1509_56353, RNA815_26897}
57. MligTC455_49225 236 4.91 Mlig455_059257

Neo: -

Age: Up-Down-Up

 VPS41 1.742 - - - 0.956 - 0.786 Mlig455_059257 {REF} {Length: 5244} {Pfam: Region in Clathrin and VPS [PF00637.22, score=59.8]; zinc-RING finger domain [PF14634.8, score=22.0]} {Human: ENSG00000006715, VPS41, VPS41, HOPS complex subunit, [RH, Score=464, Expect=5e-150]} {Mouse: ENSMUSG00000041236, Vps41, VPS41 HOPS complex subunit, [RH, Score=459, Expect=3e-148]} {Dmel: FBgn0002566, lt, light, [RH, Score=401, Expect=2e-126]} {Celegans: WBGene00017974, vps-41, Vacuolar protein sorting-associated protein 41 homolog, [RH, Score=303, Expect=2e-89]} {Smed: dd_Smed_v6_3481_0_1, dd_Smed_v6_3481_0_1, [RH, Score=390, Expect=7e-122]} {RNA1509_34132} {RNA1310_6719} {RNA815_4867}
58. MligTC455_41202 366 7.62 Mlig455_062321

Neo: -

Age: Down-Up-Down

 ARFIP2 1.74 - - - 0.968 0.772 - Mlig455_062321 {REF} {Length: 3538} {TRANSSPLICED} {Pfam: Arfaptin-like domain [PF06456.15, score=170.5]} {Human: ENSG00000132254, ARFIP2, ADP ribosylation factor interacting protein 2, [Score=222, Expect=4e-70]; ENSG00000164144, ARFIP1, ADP ribosylation factor interacting protein 1, [Score=222, Expect=1e-69]} {Mouse: ENSMUSG00000074513, Arfip1, ADP-ribosylation factor interacting protein 1, [Score=223, Expect=4e-70]; ENSMUSG00000030881, Arfip2, ADP-ribosylation factor interacting protein 2, [Score=221, Expect=1e-69]; ENSMUSG00000102805, Gm37240, predicted gene, 37240, [Score=220, Expect=2e-70]} {Dmel: FBgn0037884, Arfip, Arfaptin, [Score=219, Expect=1e-68]} {Celegans: WBGene00010040, F54C8.7, [Score=122, Expect=2e-32]} {Smed: dd_Smed_v6_5732_0_1, dd_Smed_v6_5732_0_1, [Score=207, Expect=8e-65]} {RNA1509_22107} {RNA1310_24267, RNA1509_22107} {RNA1509_22107, RNA815_18488}
59. MligTC455_50791 850 17.7 Mlig455_049295

Neo: -

Age: -

 1.736 - - - 0.960 - 0.776 Mlig455_049295 {REF} {Length: 1117} {TRANSSPLICED} {RNA1509_20394, RNA1509_34054} {RNA1310_29625, RNA1509_20394} {RNA1509_20394, RNA815_17224}
60. MligTC455_20965 992 20.66 Mlig455_067700

Neo: Int S/G2/M

Age: Up-Down-Up, logFC(26M/2M)=0.716

 FDPS 1.735 0.777 - - 0.958 - - Mlig455_067700 {REF} {Length: 1960} {TRANSSPLICED} {Pfam: Polyprenyl synthetase [PF00348.19, score=162.5]} {Human: ENSG00000160752, FDPS, farnesyl diphosphate synthase, [Score=139, Expect=4e-37]} {Mouse: ENSMUSG00000105204, Gm43738, predicted gene 43738, [RH, Score=144, Expect=1e-37]} {Dmel: FBgn0025373, Fpps, Farnesyl pyrophosphate synthase, [Score=154, Expect=6e-43]} {Celegans: WBGene00011058, fdps-1, Farnesyl DiPhosphate Synthetase, [Score=113, Expect=2e-28]} {Smed: dd_Smed_v6_13592_0_1, dd_Smed_v6_13592_0_1, [Score=141, Expect=5e-39]} {RNA1509_43196, RNA1509_46820} {RNA1310_14434, RNA1509_43196} {RNA1509_43196, RNA815_12356}
61. MligTC455_52010 453 9.44 Mlig455_027970

Neo: Irradiation

Age: Up-Down-Down

Region-enriched R4: 1.597/0.00358

 ADAM9 1.735 - - 0.779 0.956 - - Mlig455_027970 {REF} {Length: 4574} {Pfam: Disintegrin [PF00200.25, score=114.6]; Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=92.6]; Metallo-peptidase family M12 [PF13688.8, score=36.4]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=30.8]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=30.2]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=19.2]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=123, Expect=2e-28]} {Mouse: ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [Score=130, Expect=2e-30]} {Dmel: FBgn0265140, Meltrin, [Score=138, Expect=6e-33]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=126, Expect=2e-29]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=132, Expect=3e-31]} {RNA1509_21270} {RNA1310_13413} {RNA815_11284.1}
62. MligTC455_23519 291 6.06 Mlig455_043085

Neo: -

Age: logFC(26M/2M)=0.337

Region-enriched R5: 1.705/0.02838

 DOLPP1 1.728 0.750 - - 0.978 - - Mlig455_043085 {REF} {Length: 1650} {Pfam: PAP2 superfamily [PF01569.23, score=51.2]} {Human: ENSG00000167130, DOLPP1, dolichyldiphosphatase 1, [Score=117, Expect=6e-33]} {Mouse: ENSMUSG00000026856, Dolpp1, dolichyl pyrophosphate phosphatase 1, [RH, Score=113, Expect=1e-32]} {Smed: dd_Smed_v6_6607_0_1, dd_Smed_v6_6607_0_1, [Score=119, Expect=2e-34]} {RNA1509_22706} {RNA1310_2620} {RNA815_4895}
63. MligTC455_41900 1108 23.08 Mlig455_016657

Neo: -

Age: -

 UFL1 1.726 - - - 0.978 - 0.748 Mlig455_016657 {REF} {Length: 2725} {TRANSSPLICED} {Pfam: E3 UFM1-protein ligase 1 [PF09743.11, score=290.7]; Winged helix-turn-helix DNA-binding [PF13412.8, score=21.7]} {Human: ENSG00000014123, UFL1, UFM1 specific ligase 1, [RH, Score=322, Expect=9e-98]} {Mouse: ENSMUSG00000040359, Ufl1, UFM1 specific ligase 1, [RH, Score=316, Expect=9e-96]} {Dmel: FBgn0037467, Ufl1, UFM1 specific ligase 1, [RH, Score=270, Expect=1e-78]} {Celegans: WBGene00015555, ufl-1, E3 UFM1-protein ligase 1 homolog, [RH, Score=162, Expect=2e-41]} {Smed: dd_Smed_v6_5571_1_1, dd_Smed_v6_5571_1_1, [RH, Score=338, Expect=3e-104]} {RNA1509_6918} {RNA1310_6721.1} {RNA815_2135}
64. MligTC455_33406 537 11.18 Mlig455_048555, Mlig455_053343

Neo: -

Age: -

Region-enriched R5: 1.304/0.00902

 GNAL 1.725 - - 0.758 0.967 - -

Mlig455_048555 {REF} {Length: 2732} {Pfam: G-protein alpha subunit [PF00503.22, score=260.9]; ADP-ribosylation factor family [PF00025.23, score=45.3]; Gtr1/RagA G protein conserved region [PF04670.14, score=29.7]} {Human: ENSG00000141404, GNAL, G protein subunit alpha L, [Score=259, Expect=4e-80]} {Mouse: ENSMUSG00000024524, Gnal, guanine nucleotide binding protein, alpha stimulating, olfactory type, [Score=259, Expect=2e-80]} {Dmel: FBgn0001123, Galphas, G protein alpha s subunit, [Score=247, Expect=5e-77]} {Celegans: WBGene00001745, gsa-1, G protein, Subunit Alpha, [Score=254, Expect=6e-80]} {Smed: dd_Smed_v6_4493_0_1, dd_Smed_v6_4493_0_1, [RH, Score=342, Expect=3e-112]} {RNA1509_49417} {RNA1310_5261.1} {RNA815_1705.1}

Mlig455_053343 {REF} {Length: 3178} {Pfam: G-protein alpha subunit [PF00503.22, score=260.9]; ADP-ribosylation factor family [PF00025.23, score=45.3]; Gtr1/RagA G protein conserved region [PF04670.14, score=29.7]} {Human: ENSG00000141404, GNAL, G protein subunit alpha L, [Score=259, Expect=4e-80]} {Mouse: ENSMUSG00000024524, Gnal, guanine nucleotide binding protein, alpha stimulating, olfactory type, [Score=259, Expect=2e-80]} {Dmel: FBgn0001123, Galphas, G protein alpha s subunit, [Score=247, Expect=5e-77]} {Celegans: WBGene00001745, gsa-1, G protein, Subunit Alpha, [Score=254, Expect=6e-80]} {Smed: dd_Smed_v6_4493_0_1, dd_Smed_v6_4493_0_1, [RH, Score=342, Expect=3e-112]} {RNA1509_49417} {RNA1310_5261.1} {RNA815_1705.1}
65. MligTC455_12731 331 6.89 Mlig455_005108

Neo: -

Age: -

Region-enriched R6: 3.150/0.01756

 1.724 - - - 0.959 0.765 - Mlig455_005108 {REF} {Length: 654} {NoTransDecoderORF} {RNA1509_44841} {RNA1310_66981} {RNA815_54535}
66. MligTC455_19163 1014 21.13 Mlig455_064974

Neo: -

Age: -

 TBL2 1.724 - - - 0.966 - 0.758 Mlig455_064974 {REF} {Length: 2885} {Pfam: WD domain, G-beta repeat [PF00400.34, score=72.6]} {Human: ENSG00000106638, TBL2, transducin beta like 2, [RH, Score=298, Expect=9e-97]} {Mouse: ENSMUSG00000005374, Tbl2, transducin (beta)-like 2, [RH, Score=284, Expect=5e-91]} {Dmel: FBgn0032030, Wdr82, WD repeat domain 82, [Score=50.1, Expect=2e-06]} {Celegans: WBGene00009784, F46C5.9, [RH, Score=176, Expect=7e-50]} {Smed: dd_Smed_v6_4372_0_1, dd_Smed_v6_4372_0_1, [RH, Score=248, Expect=2e-77]} {RNA1509_52503, RNA1509_8303} {RNA1310_11971, RNA1509_52503} {RNA1509_52503, RNA815_4594}
67. MligTC455_32985 415 8.65 Mlig455_046914

Neo: -

Age: Up-Up-Down

 1.723 0.761 - - 0.962 - - Mlig455_046914 {REF} {Length: 2316} {Pfam: Kazal-type serine protease inhibitor domain [PF18434.3, score=47.7]} {RNA1509_16553} {RNA1310_30330.1} {RNA815_16460}
68. MligTC455_50724 402 8.37 Mlig455_007823

Neo: -

Age: -

Region-enriched R5: 1.057/0.03844

 NRBP1 1.719 - 0.757 - 0.962 - - Mlig455_007823 {REF} {Length: 5624} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=66.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=37.5]} {Human: ENSG00000115216, NRBP1, nuclear receptor binding protein 1, [RH, Score=188, Expect=4e-50]} {Mouse: ENSMUSG00000029148, Nrbp1, nuclear receptor binding protein 1, [RH, Score=184, Expect=6e-49]} {Dmel: FBgn0027497, Madm, MLF1-adaptor molecule, [RH, Score=153, Expect=4e-38]} {Celegans: WBGene00010427, hpo-11, [RH, Score=169, Expect=1e-43]} {Smed: dd_Smed_v6_5859_0_1, dd_Smed_v6_5859_0_1, [RH, Score=199, Expect=3e-52]} {RNA1509_18578, RNA1509_19619, RNA1509_33489} {RNA1310_6856, RNA1509_18578, RNA1509_19619, RNA1509_33489} {RNA1509_18578, RNA1509_19619, RNA1509_33489, RNA815_11040}
69. MligTC455_14050 356 7.42 Mlig455_052818

Neo: -

Age: -

 1.717 - - - 0.960 0.757 - Mlig455_052818 {REF} {Length: 2718} {Pfam: Ubiquitin family [PF00240.25, score=51.8]; Ubiquitin-2 like Rad60 SUMO-like [PF11976.10, score=26.9]} {RNA1509_11983} {RNA1310_7335} {RNA815_858}
70. MligTC455_17506 450 9.38 Mlig455_015262

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.648

Region-enriched R4: 1.874/0.03652

 1.712 - - - 0.966 - 0.746 Mlig455_015262 {REF} {Length: 2975} {TRANSSPLICED} {RNA1509_4515} {RNA1310_5427} {RNA815_2140.1}
71. MligTC455_45474 281 5.86 Mlig455_045349

Neo: Int S/G2/M

Age: -

 1.703 - - - 0.965 - 0.738 Mlig455_045349 {REF} {Length: 3749} {TRANSSPLICED} {Pfam: Ring finger domain [PF13639.8, score=37.4]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=24.6]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=23.3]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=21.5]} {Mouse: ENSMUSG00000038611, Phrf1, PHD and ring finger domains 1, [Score=50.1, Expect=2e-06]} {RNA1509_44163} {RNA1310_8209.1, RNA1509_44163} {RNA1509_44163, RNA815_13026.1}
72. MligTC455_19706 198 4.12 Mlig455_049566

Neo: Int S/G2/M

Age: -

 DNA2 1.699 0.724 - - - 0.975 - Mlig455_049566 {REF} {Length: 5005} {TRANSSPLICED} {Pfam: AAA domain [PF13087.8, score=141.8]; DNA replication factor Dna2 [PF08696.13, score=130.0]; AAA domain [PF13086.8, score=117.0]; AAA domain [PF13604.8, score=53.2]; AAA domain [PF13245.8, score=31.7]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=20.1]; Threonylcarbamoyl adenosine biosynthesis protein TsaE [PF02367.19, score=19.6]; AAA domain [PF13481.8, score=18.3]} {Human: ENSG00000138346, DNA2, DNA replication helicase/nuclease 2, [RH, Score=411, Expect=2e-124]} {Mouse: ENSMUSG00000036875, Dna2, DNA replication helicase/nuclease 2, [RH, Score=416, Expect=2e-126]} {Dmel: FBgn0030170, CG2990, [RH, Score=364, Expect=3e-107]} {Celegans: WBGene00001016, dna-2, Yeast DNA helicase/endonuclease family, [RH, Score=351, Expect=7e-103]} {Smed: dd_Smed_v6_12638_0_1, dd_Smed_v6_12638_0_1, [RH, Score=404, Expect=1e-121]} {RNA1509_15095} {RNA1310_5852, RNA1509_15095} {RNA1509_15095, RNA815_1653.1}
73. MligTC455_15341 1286 26.78 Mlig455_018588

Neo: -

Age: logFC(26M/2M)=0.189

 SLC9A6 1.685 - - - 0.955 - 0.730 Mlig455_018588 {REF} {Length: 3988} {Pfam: Sodium/hydrogen exchanger family [PF00999.23, score=258.0]} {Human: ENSG00000198689, SLC9A6, solute carrier family 9 member A6, [RH, Score=549, Expect=0.0]; ENSG00000065923, SLC9A7, solute carrier family 9 member A7, [RH, Score=548, Expect=0.0]; ENSG00000181804, SLC9A9, solute carrier family 9 member A9, [RH, Score=544, Expect=0.0]} {Mouse: ENSMUSG00000060681, Slc9a6, solute carrier family 9 (sodium/hydrogen exchanger), member 6, [RH, Score=548, Expect=0.0]; ENSMUSG00000037341, Slc9a7, solute carrier family 9 (sodium/hydrogen exchanger), member 7, [RH, Score=545, Expect=0.0]; ENSMUSG00000031129, Slc9a9, solute carrier family 9 (sodium/hydrogen exchanger), member 9, [RH, Score=543, Expect=0.0]} {Dmel: FBgn0028703, Nhe3, Na[+]/H[+] hydrogen exchanger 3, [RH, Score=566, Expect=0.0]} {Celegans: WBGene00003733, nhx-5, Sodium/hydrogen exchanger, [RH, Score=483, Expect=2e-163]} {Smed: dd_Smed_v6_5461_0_1, dd_Smed_v6_5461_0_1, [RH, Score=592, Expect=0.0]} {RNA1509_47834} {RNA1310_6716} {RNA815_3552}
74. MligTC455_50037 209 4.34 Mlig455_004260

Neo: Germline

Age: -

Region-specific R4: 5.598

Region-enriched R4: 2.452/0.00729

 1.685 - - 0.723 0.962 - - Mlig455_004260 {REF} {Length: 1742} {Pfam: Innexin [PF00876.20, score=258.9]} {Dmel: FBgn0085387, shakB, shaking B, [Score=85.1, Expect=6e-18]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=173, Expect=1e-49]} {Smed: dd_Smed_v6_8019_0_1, dd_Smed_v6_8019_0_1, [Score=251, Expect=5e-79]} {RNA1509_11630} {RNA1310_21997} {RNA815_9078}
75. MligTC455_28255 916 19.07 Mlig455_030816

Neo: -

Age: Down-Up-Down

 DUSP16 1.684 0.733 - - 0.951 - - Mlig455_030816 {REF} {Length: 2559} {TRANSSPLICED} {Pfam: Dual specificity phosphatase, catalytic domain [PF00782.22, score=131.7]; Rhodanese-like domain [PF00581.22, score=24.5]; Protein-tyrosine phosphatase [PF00102.29, score=18.7]} {Human: ENSG00000111266, DUSP16, dual specificity phosphatase 16, [RH, Score=244, Expect=7e-73]; ENSG00000184545, DUSP8, dual specificity phosphatase 8, [RH, Score=244, Expect=3e-73]; ENSG00000280962, DUSP16, dual specificity phosphatase 16, [RH, Score=244, Expect=7e-73]; ENSG00000273793, DUSP8, dual specificity phosphatase 8, [RH, Score=244, Expect=3e-73]; ENSG00000278165, DUSP8, dual specificity phosphatase 8, [RH, Score=244, Expect=3e-73]} {Mouse: ENSMUSG00000030203, Dusp16, dual specificity phosphatase 16, [RH, Score=244, Expect=3e-73]; ENSMUSG00000037887, Dusp8, dual specificity phosphatase 8, [RH, Score=243, Expect=2e-72]} {Dmel: FBgn0036844, Mkp3, Mitogen-activated protein kinase phosphatase 3, [RH, Score=148, Expect=6e-39]} {Celegans: WBGene00006923, vhp-1, Tyrosine-protein phosphatase vhp-1, [RH, Score=209, Expect=3e-60]} {Smed: dd_Smed_v6_8066_0_1, dd_Smed_v6_8066_0_1, [Score=158, Expect=7e-42]} {RNA1509_23189} {RNA1310_8102.1} {RNA815_3235}
76. MligTC455_45376 648 13.5 Mlig455_035112

Neo: -

Age: logFC(26M/2M)=0.360

 PFKFB1 1.684 - - - 0.962 - 0.722 Mlig455_035112 {REF} {Length: 2708} {Pfam: 6-phosphofructo-2-kinase [PF01591.20, score=288.1]; Histidine phosphatase superfamily (branch 1) [PF00300.24, score=129.5]; AAA domain [PF13671.8, score=26.8]} {Human: ENSG00000158571, PFKFB1, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1, [RH, Score=522, Expect=0.0]; ENSG00000123836, PFKFB2, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2, [RH, Score=506, Expect=9e-176]; ENSG00000114268, PFKFB4, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, [RH, Score=502, Expect=1e-174]; ENSG00000170525, PFKFB3, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, [RH, Score=496, Expect=1e-171]} {Mouse: ENSMUSG00000025271, Pfkfb1, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1, [RH, Score=522, Expect=0.0]; ENSMUSG00000026773, Pfkfb3, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, [RH, Score=505, Expect=5e-176]; ENSMUSG00000025648, Pfkfb4, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4, [RH, Score=504, Expect=2e-175]; ENSMUSG00000026409, Pfkfb2, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2, [RH, Score=500, Expect=8e-174]} {Dmel: FBgn0027621, Pfrx, 6-phosphofructo-2-kinase, [RH, Score=485, Expect=9e-165]} {Celegans: WBGene00019295, pfkb-1.2, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 6-phosphofructo-2-kinase Fructose-2,6-bisphosphatase, [RH, Score=451, Expect=3e-155]} {Smed: dd_Smed_v6_3959_0_1, dd_Smed_v6_3959_0_1, [RH, Score=533, Expect=0.0]} {RNA1509_15746} {RNA1310_8036.1} {RNA815_2585.1}
77. MligTC455_52280 259 5.39 Mlig455_040265, Mlig455_040274

Neo: -

Age: logFC(26M/2M)=-1.013

 1.683 - - 0.722 0.961 - -

Mlig455_040265 {REF} {Length: 617} {RNA1509_1537} {RNA1310_19960} {RNA815_6565}

Mlig455_040274 {REF} {Length: 706} {RNA1509_1537} {RNA1310_85398} {RNA815_32362}
78. MligTC455_47937 1817 37.85 Mlig455_007819

Neo: -

Age: -

 LYPLA2 1.68 - - - 0.953 - 0.727 Mlig455_007819 {REF} {Length: 1709} {Pfam: Phospholipase/Carboxylesterase [PF02230.18, score=237.8]; Alpha/beta hydrolase family [PF12697.9, score=25.2]; Serine aminopeptidase, S33 [PF12146.10, score=23.4]; alpha/beta hydrolase fold [PF07859.15, score=21.7]; Prolyl oligopeptidase family [PF00326.23, score=21.6]; Dienelactone hydrolase family [PF01738.20, score=21.3]} {Human: ENSG00000011009, LYPLA2, lysophospholipase II, [RH, Score=214, Expect=1e-69]; ENSG00000120992, LYPLA1, lysophospholipase I, [RH, Score=211, Expect=2e-68]} {Mouse: ENSMUSG00000025903, Lypla1, lysophospholipase 1, [RH, Score=216, Expect=2e-70]; ENSMUSG00000028670, Lypla2, lysophospholipase 2, [RH, Score=214, Expect=6e-70]} {Dmel: FBgn0042138, CG18815, [RH, Score=216, Expect=5e-71]} {Celegans: WBGene00010564, ath-1, Acyl protein THioesterase family, [RH, Score=194, Expect=4e-62]} {Smed: dd_Smed_v6_638_0_1, dd_Smed_v6_638_0_1, [RH, Score=218, Expect=2e-71]} {RNA1509_20687, RNA1509_23013} {RNA1310_28247, RNA1509_20687, RNA1509_23013} {RNA1509_20687, RNA1509_23013, RNA815_12780}
79. MligTC455_17085 220 4.57 Mlig455_010614

Neo: -

Age: -

Region-enriched R5: 2.140/0.00793

 SHOC2 1.673 0.714 - - 0.959 - - Mlig455_010614 {REF} {Length: 7396} {TRANSSPLICED} {Pfam: Leucine rich repeat [PF13855.8, score=170.1]; Leucine Rich repeats (2 copies) [PF12799.9, score=106.5]; Carboxypeptidase regulatory-like domain [PF13620.8, score=96.7]; Prealbumin-like fold domain [PF17802.3, score=44.0]; Protein of unknown function (DUF2012) [PF09430.12, score=43.8]; SdrD B-like domain [PF17210.5, score=39.2]; CarboxypepD_reg-like domain [PF13715.8, score=27.4]; Protein of unknown function (DUF1416) [PF07210.14, score=21.7]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=20.8]; Leucine-rich repeat [PF14580.8, score=19.9]} {Human: ENSG00000108061, SHOC2, SHOC2, leucine rich repeat scaffold protein, [RH, Score=567, Expect=0.0]} {Mouse: ENSMUSG00000024976, Shoc2, Shoc2, leucine rich repeat scaffold protein, [RH, Score=562, Expect=0.0]} {Dmel: FBgn0038504, Sur-8, [RH, Score=564, Expect=0.0]} {Celegans: WBGene00004929, soc-2, Leucine-rich repeat protein soc-2, [RH, Score=506, Expect=3e-163]} {Smed: dd_Smed_v6_1909_0_1, dd_Smed_v6_1909_0_1, [RH, Score=663, Expect=0.0]} {RNA1509_3897} {RNA1310_2809.1} {RNA815_7195}
80. MligTC455_04860 2094 43.62 Mlig455_024949

Neo: -

Age: -

 LITAF 1.671 - - 0.714 0.957 - - Mlig455_024949 {REF} {Length: 2362} {TRANSSPLICED} {Pfam: LITAF-like zinc ribbon domain [PF10601.11, score=80.8]} {Human: ENSG00000189067, LITAF, lipopolysaccharide induced TNF factor, [Score=61.6, Expect=3e-12]} {Mouse: ENSMUSG00000022500, Litaf, LPS-induced TN factor, [Score=63.5, Expect=4e-13]} {Dmel: FBgn0050273, CG30273, [RH, Score=77.0, Expect=9e-19]} {Celegans: WBGene00012549, Y37D8A.8, [RH, Score=57.4, Expect=2e-11]} {Smed: dd_Smed_v6_10754_0_1, dd_Smed_v6_10754_0_1, [RH, Score=82.0, Expect=6e-21]} {RNA1509_38480, RNA1509_58765, RNA1509_58780, RNA1509_7303} {RNA1310_18499.1, RNA1509_38480, RNA1509_58765, RNA1509_58780} {RNA1509_38480, RNA1509_58765, RNA1509_58780, RNA815_28299}
81. MligTC455_15213 185 3.86 Mlig455_016234

Neo: Germline

Age: Down-Down-Up

Region-specific R4: 6.170

Region-enriched R4: 3.719/0.00184

 TPMT 1.669 - - - 0.961 0.708 - Mlig455_016234 {REF} {Length: 1311} {Pfam: Thiopurine S-methyltransferase (TPMT) [PF05724.13, score=80.4]} {Human: ENSG00000137364, TPMT, thiopurine S-methyltransferase, [Score=74.7, Expect=6e-15]} {Mouse: ENSMUSG00000021376, Tpmt, thiopurine methyltransferase, [Score=63.5, Expect=3e-11]} {Smed: dd_Smed_v6_1495_0_1, dd_Smed_v6_1495_0_1, [RH, Score=78.2, Expect=1e-16]} {RNA1509_43164} {RNA1310_29080, RNA1509_43164} {RNA1509_43164, RNA815_13368}
82. MligTC455_43329 235 4.9 Mlig455_007154

Neo: -

Age: -

Region-enriched R2: 3.268/0.02528
Region-enriched R5: 2.289/0.03532

 SMURF2 1.667 - - - 0.959 0.708 - Mlig455_007154 {REF} {Length: 4687} {Pfam: HECT-domain (ubiquitin-transferase) [PF00632.27, score=303.1]; WW domain [PF00397.28, score=64.2]} {Human: ENSG00000108854, SMURF2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=636, Expect=0.0]} {Mouse: ENSMUSG00000018363, Smurf2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=637, Expect=0.0]} {Dmel: FBgn0259174, Nedd4, [Score=409, Expect=4e-133]} {Celegans: WBGene00022358, Y92H12A.2, E3 ubiquitin-protein ligase, [Score=400, Expect=2e-133]} {Smed: dd_Smed_v6_7322_0_1, dd_Smed_v6_7322_0_1, [Score=398, Expect=2e-128]} {RNA1509_42014} {RNA1310_6371} {RNA815_17584}
83. MligTC455_16141 1644 34.25 Mlig455_064276

Neo: Irradiation

Age: Down-Down-Up

Region-enriched R5: 1.589/0.00000

 HPDL 1.664 0.714 - - 0.950 - - Mlig455_064276 {REF} {Length: 1629} {TRANSSPLICED} {Pfam: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily [PF00903.27, score=26.5]; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily [PF13669.8, score=23.0]} {Human: ENSG00000186603, HPDL, 4-hydroxyphenylpyruvate dioxygenase like, [RH, Score=120, Expect=5e-30]} {Mouse: ENSMUSG00000043155, Hpdl, 4-hydroxyphenylpyruvate dioxygenase-like, [RH, Score=127, Expect=1e-32]} {Dmel: FBgn0036992, CG11796, [Score=103, Expect=7e-25]} {Celegans: WBGene00016294, C31H2.4, Putative protein C31H2.4, [Score=103, Expect=2e-24]} {Smed: dd_Smed_v6_13579_0_1, dd_Smed_v6_13579_0_1, [RH, Score=166, Expect=1e-47]} {RNA1509_3068} {RNA1310_18738} {RNA815_12614}
84. MligTC455_41761 655 13.65 Mlig455_020225

Neo: Irradiation

Age: -

Region-enriched R5: 1.227/0.00118

 PTPRZ1 1.661 - 0.703 - 0.958 - - Mlig455_020225 {REF} {Length: 5464} {TRANSSPLICED} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=409.3]; Fibronectin type III domain [PF00041.23, score=83.6]; Dual specificity phosphatase, catalytic domain [PF00782.22, score=24.2]} {Human: ENSG00000106278, PTPRZ1, protein tyrosine phosphatase, receptor type Z1, [RH, Score=492, Expect=4e-149]; ENSG00000144724, PTPRG, protein tyrosine phosphatase, receptor type G, [RH, Score=492, Expect=4e-149]} {Mouse: ENSMUSG00000068748, Ptprz1, protein tyrosine phosphatase, receptor type Z, polypeptide 1, [RH, Score=491, Expect=6e-145]; ENSMUSG00000021745, Ptprg, protein tyrosine phosphatase, receptor type, G, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0004369, Ptp99A, Protein tyrosine phosphatase 99A, [RH, Score=469, Expect=9e-143]} {Celegans: WBGene00004215, ptp-3, Tyrosine-protein phosphatase Lar-like, [Score=348, Expect=9e-101]} {Smed: dd_Smed_v6_6997_0_1, dd_Smed_v6_6997_0_1, [RH, Score=564, Expect=9e-177]} {RNA1509_4639} {RNA1310_810} {RNA815_3651}
85. MligTC455_27796 664 13.84 Mlig455_005664

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.450

 HELZ2 0.995 - - - - 0.995 - Mlig455_005664 {REF} {Length: 8120} {Pfam: RNB domain [PF00773.21, score=158.5]; AAA domain [PF13086.8, score=134.0]; AAA domain [PF13087.8, score=128.8]; AAA domain [PF13604.8, score=26.8]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=21.9]; UvrD-like helicase C-terminal domain [PF13361.8, score=19.7]; UvrD-like helicase C-terminal domain [PF13538.8, score=19.6]} {Human: ENSG00000130589, HELZ2, helicase with zinc finger 2, [Score=148, Expect=6e-35]} {Mouse: ENSMUSG00000027580, Helz2, helicase with zinc finger 2, transcriptional coactivator, [Score=146, Expect=3e-34]} {Dmel: FBgn0039183, Dis3, [Score=110, Expect=8e-24]} {Celegans: WBGene00018612, disl-2, DIS3-like exonuclease 2, [Score=103, Expect=8e-22]} {Smed: dd_Smed_v6_8176_0_1, dd_Smed_v6_8176_0_1, [RH, Score=326, Expect=7e-90]} {RNA1509_18632} {RNA1310_275} {RNA815_982.1}
86. MligTC455_30556 1069 22.26 Mlig455_014350

Neo: Irradiation

Age: -

 UBE2H 0.989 - - - - 0.989 - Mlig455_014350 {REF} {Length: 4504} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=126.6]} {Human: ENSG00000186591, UBE2H, ubiquitin conjugating enzyme E2 H, [RH, Score=300, Expect=5e-105]} {Mouse: ENSMUSG00000039159, Ube2h, ubiquitin-conjugating enzyme E2H, [RH, Score=300, Expect=3e-105]} {Dmel: FBgn0029996, UbcE2H, Ubiquitin conjugating enzyme E2H, [RH, Score=280, Expect=3e-97]} {Celegans: WBGene00006705, ubc-8, UBiquitin Conjugating enzyme, [RH, Score=249, Expect=1e-84]} {Smed: dd_Smed_v6_4514_0_1, dd_Smed_v6_4514_0_1, [RH, Score=273, Expect=5e-95]} {RNA1509_15196, RNA1509_39195, RNA1509_41009, RNA1509_43077, RNA1509_46887, RNA1509_9318, RNA1509_9451} {RNA1310_31599, RNA1509_15196, RNA1509_39195, RNA1509_41009, RNA1509_43077, RNA1509_46887, RNA1509_9451} {RNA1509_15196, RNA1509_39195, RNA1509_41009, RNA1509_43077, RNA1509_46887, RNA1509_9451, RNA815_15483}
87. MligTC455_22967 511 10.65 Mlig455_025359

Neo: -

Age: Up-Down-Down

Region-enriched R4: 1.418/0.03872

 NCK2 0.986 - - - 0.986 - - Mlig455_025359 {REF} {Length: 4945} {TRANSSPLICED} {Pfam: SH3 domain [PF00018.30, score=149.7]; Variant SH3 domain [PF14604.8, score=137.1]; Variant SH3 domain [PF07653.19, score=83.1]; SH2 domain [PF00017.26, score=58.0]; Bacterial SH3 domain [PF08239.13, score=33.5]; SH3 domain [PF17902.3, score=28.6]; Bacterial dipeptidyl-peptidase Sh3 domain [PF18348.3, score=18.3]} {Human: ENSG00000071051, NCK2, NCK adaptor protein 2, [Score=226, Expect=1e-68]} {Mouse: ENSMUSG00000032475, Nck1, non-catalytic region of tyrosine kinase adaptor protein 1, [Score=163, Expect=2e-45]} {Dmel: FBgn0010583, dock, dreadlocks, [Score=129, Expect=2e-32]} {Celegans: WBGene00006410, nck-1, NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family, [Score=219, Expect=5e-66]} {Smed: dd_Smed_v6_4816_0_2, dd_Smed_v6_4816_0_2, [Score=215, Expect=2e-62]} {RNA1509_17077, RNA1509_34254, RNA1509_52928} {RNA1310_9858, RNA1509_17077, RNA1509_34254, RNA1509_52928} {RNA1509_17077, RNA1509_34254, RNA1509_52928, RNA815_11879}
88. MligTC455_23242 633 13.19 Mlig455_001209

Neo: -

Age: -

Region-enriched R5: 1.808/0.00013

 SLC7A14 0.985 - - - 0.985 - - Mlig455_001209 {REF} {Length: 3590} {Pfam: Amino acid permease [PF13520.8, score=127.0]; Amino acid permease [PF00324.23, score=113.5]; C-terminus of AA_permease [PF13906.8, score=74.4]} {Human: ENSG00000013293, SLC7A14, solute carrier family 7 member 14, [RH, Score=480, Expect=1e-157]} {Mouse: ENSMUSG00000069072, Slc7a14, solute carrier family 7 (cationic amino acid transporter, y+ system), member 14, [RH, Score=471, Expect=4e-154]} {Dmel: FBgn0036764, CG5535, [Score=379, Expect=4e-121]} {Celegans: WBGene00016806, C50D2.2, [Score=338, Expect=5e-106]} {Smed: dd_Smed_v6_16390_0_1, dd_Smed_v6_16390_0_1, [Score=332, Expect=3e-106]} {RNA1509_29954} {RNA1310_7437} {RNA815_3407}
89. MligTC455_42832 1461 30.43 Mlig455_024317, Mlig455_024488

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.326

Regeneration-upregulated BL: 1.723

Regeneration-enriched BL: 1.723

 GPKOW 0.984 - - - 0.984 - -

Mlig455_024317 {REF} {Length: 1765} {TRANSSPLICED} {Pfam: G-patch domain [PF12656.9, score=49.3]; KOW motif [PF00467.31, score=21.1]} {Human: ENSG00000068394, GPKOW, G-patch domain and KOW motifs, [RH, Score=91.3, Expect=3e-19]} {Mouse: ENSMUSG00000031148, Gpkow, G patch domain and KOW motifs, [RH, Score=87.8, Expect=3e-18]} {Dmel: FBgn0038454, CG10324, [Score=56.6, Expect=3e-08]} {Celegans: WBGene00011237, gkow-1, G patch domain and KOW motifs-containing protein homolog 1, [RH, Score=89.4, Expect=5e-19]} {RNA1509_19504} {RNA1310_9244} {RNA815_26106}

Mlig455_024488 {REF} {Length: 1953} {TRANSSPLICED} {Pfam: G-patch domain [PF12656.9, score=49.3]; KOW motif [PF00467.31, score=20.9]} {Human: ENSG00000068394, GPKOW, G-patch domain and KOW motifs, [RH, Score=90.5, Expect=6e-19]} {Mouse: ENSMUSG00000031148, Gpkow, G patch domain and KOW motifs, [RH, Score=84.3, Expect=4e-17]} {Dmel: FBgn0038454, CG10324, [Score=56.2, Expect=3e-08]} {Celegans: WBGene00011237, gkow-1, G patch domain and KOW motifs-containing protein homolog 1, [RH, Score=83.2, Expect=6e-17]} {RNA1509_19504} {RNA1310_9244} {RNA815_24204}
90. MligTC455_22780 78 1.62 Mlig455_006831

Neo: -

Age: Up-Down-Down

 KIF13A 0.98 - - - 0.980 - - Mlig455_006831 {REF} {Length: 6453} {Pfam: Kinesin motor domain [PF00225.25, score=378.3]; Microtubule binding [PF16796.7, score=89.6]; Kinesin-associated [PF16183.7, score=86.7]; CAP-Gly domain [PF01302.27, score=81.4]; Kinesin protein [PF12473.10, score=62.7]; FHA domain [PF00498.28, score=28.6]; Kinesin protein 1B [PF12423.10, score=25.5]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=19.4]} {Human: ENSG00000137177, KIF13A, kinesin family member 13A, [RH, Score=1233, Expect=0.0]; ENSG00000197892, KIF13B, kinesin family member 13B, [RH, Score=1186, Expect=0.0]} {Mouse: ENSMUSG00000060012, Kif13b, kinesin family member 13B, [RH, Score=1240, Expect=0.0]; ENSMUSG00000021375, Kif13a, kinesin family member 13A, [RH, Score=1228, Expect=0.0]} {Dmel: FBgn0019968, Khc-73, Kinesin heavy chain 73, [RH, Score=1284, Expect=0.0]} {Celegans: WBGene00002217, klp-4, Kinesin-like protein, [RH, Score=1050, Expect=0.0]} {Smed: dd_Smed_v6_7089_0_1, dd_Smed_v6_7089_0_1, [RH, Score=1059, Expect=0.0]} {RNA1509_5948} {RNA1310_476.1} {RNA815_1117}
91. MligTC455_37959 177 3.69 Mlig455_038764

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.399

 SCNN1B 0.979 - - - 0.979 - - Mlig455_038764 {REF} {Length: 3158} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=192.0]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=49.7, Expect=1e-05]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=68.9, Expect=7e-12]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=57.4, Expect=2e-08]} {Smed: dd_Smed_v6_26855_0_1, dd_Smed_v6_26855_0_1, [Score=168, Expect=4e-45]} {RNA1509_35658, RNA1509_58401} {RNA1310_10317.1, RNA1509_35658, RNA1509_58401} {RNA1509_35658, RNA1509_58401, RNA815_3305}
92. MligTC455_48952 192 3.99 Mlig455_025241

Neo: -

Age: -

 0.979 - - - 0.979 - - Mlig455_025241 {REF} {Length: 1573} {RNA1509_50956} {RNA1310_66253.1} {RNA815_9458.1}
93. MligTC455_18932 1114 23.2 Mlig455_050787

Neo: -

Age: -

 PPP2R1A 0.977 - - - - 0.977 - Mlig455_050787 {REF} {Length: 6735} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=24.0} {Pfam: HEAT repeat [PF02985.24, score=104.0]; HEAT repeats [PF13646.8, score=103.0]; Adaptin N terminal region [PF01602.22, score=56.3]; Vacuolar 14 Fab1-binding region [PF12755.9, score=43.4]; HEAT-like repeat [PF13513.8, score=37.5]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=30.8]; Nuclear condensing complex subunits, C-term domain [PF12719.9, score=27.1]; PBS lyase HEAT-like repeat [PF03130.18, score=24.4]; Cell morphogenesis C-terminal [PF14225.8, score=22.5]} {Human: ENSG00000105568, PPP2R1A, protein phosphatase 2 scaffold subunit Aalpha, [Score=195, Expect=1e-53]; ENSG00000137713, PPP2R1B, protein phosphatase 2 scaffold subunit Abeta, [Score=194, Expect=1e-52]} {Mouse: ENSMUSG00000032058, Ppp2r1b, protein phosphatase 2, regulatory subunit A, beta, [Score=195, Expect=7e-53]; ENSMUSG00000007564, Ppp2r1a, protein phosphatase 2, regulatory subunit A, alpha, [Score=194, Expect=2e-53]} {Dmel: FBgn0260439, Pp2A-29B, Protein phosphatase 2A at 29B, [Score=147, Expect=5e-37]} {Celegans: WBGene00003901, paa-1, Probable serine/threonine-protein phosphatase PP2A regulatory subunit, [Score=165, Expect=3e-43]} {Smed: dd_Smed_v6_3840_0_1, dd_Smed_v6_3840_0_1, [RH, Score=382, Expect=3e-124]} {RNA1509_2837} {RNA1310_5699, RNA1509_2837} {RNA1509_2837, RNA815_2036.1}
94. MligTC455_51263 260 5.42 Mlig455_054142

Neo: -

Age: Down-Up-Down

 STRAP 0.977 - - - 0.977 - - Mlig455_054142 {REF} {Length: 1865} {Pfam: WD domain, G-beta repeat [PF00400.34, score=75.5]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.5]} {Human: ENSG00000023734, STRAP, serine/threonine kinase receptor associated protein, [Score=253, Expect=7e-82]} {Mouse: ENSMUSG00000030224, Strap, serine/threonine kinase receptor associated protein, [Score=253, Expect=4e-82]} {Dmel: FBgn0034876, wmd, wing morphogenesis defect, [Score=292, Expect=4e-98]} {Celegans: WBGene00001232, eif-3.I, Eukaryotic translation initiation factor 3 subunit I, [Score=74.3, Expect=7e-15]} {Smed: dd_Smed_v6_4502_0_1, dd_Smed_v6_4502_0_1, [Score=249, Expect=3e-81]} {RNA1509_35607} {RNA1310_16941.1} {RNA815_9660.1}
95. MligTC455_18882 322 6.71 Mlig455_067755

Neo: -

Age: -

 0.976 - - - 0.976 - - Mlig455_067755 {REF} {Length: 2949} {Pfam: TIR domain [PF13676.8, score=89.7]; TIR domain [PF01582.22, score=43.6]} {Smed: dd_Smed_v6_9201_0_1, dd_Smed_v6_9201_0_1, [RH, Score=303, Expect=2e-90]} {RNA1509_17089} {RNA1310_6087.1} {RNA815_12761}
96. MligTC455_44426 77 1.61 Mlig455_042257

Neo: -

Age: -

 IPO11 0.976 - - - 0.976 - - Mlig455_042257 {REF} {Length: 3743} {TRANSSPLICED} {Pfam: Importin-beta N-terminal domain [PF03810.21, score=40.6]} {Human: ENSG00000086200, IPO11, importin 11, [RH, Score=132, Expect=8e-31]} {Mouse: ENSMUSG00000042590, Ipo11, importin 11, [RH, Score=132, Expect=4e-31]} {Dmel: FBgn0284254, Impbeta11, Importin beta11, [RH, Score=97.1, Expect=4e-20]} {RNA1509_12338} {RNA1310_4949.1, RNA1509_12338} {RNA1509_12338, RNA815_1982}
97. MligTC455_26232 237 4.94 Mlig455_044561

Neo: Irradiation

Age: Down-Up-Down

 PHF8 0.975 - - - 0.975 - - Mlig455_044561 {REF} {Length: 3787} {TRANSSPLICED} {Pfam: Jumonji helical domain [PF17811.3, score=64.9]; JmjC domain, hydroxylase [PF02373.24, score=26.0]; Cupin-like domain [PF13621.8, score=25.6]} {Human: ENSG00000172943, PHF8, PHD finger protein 8, [RH, Score=291, Expect=2e-86]; ENSG00000006459, KDM7A, lysine demethylase 7A, [RH, Score=289, Expect=3e-86]} {Mouse: ENSMUSG00000041229, Phf8, PHD finger protein 8, [RH, Score=291, Expect=2e-86]; ENSMUSG00000042599, Kdm7a, lysine (K)-specific demethylase 7A, [RH, Score=287, Expect=9e-86]} {Dmel: FBgn0037659, Kdm2, Lysine (K)-specific demethylase 2, [Score=234, Expect=8e-66]} {Celegans: WBGene00017920, jmjd-1.2, Lysine-specific demethylase 7 homolog, [RH, Score=238, Expect=4e-68]} {Smed: dd_Smed_v6_10417_0_1, dd_Smed_v6_10417_0_1, [RH, Score=282, Expect=4e-89]} {RNA1509_14419} {RNA1310_7326, RNA1509_14419} {RNA1509_14419, RNA815_2278.1}
98. MligTC455_46914 423 8.82 Mlig455_060252

Neo: Irradiation

Age: -

 NOTCH3 0.975 - - - 0.975 - - Mlig455_060252 {REF} {Length: 3099} {Pfam: EGF-like domain [PF00008.29, score=49.3]; Calcium-binding EGF domain [PF07645.17, score=39.7]; Human growth factor-like EGF [PF12661.9, score=29.8]; EGF domain [PF12947.9, score=25.8]; EGF-like domain [PF07974.15, score=23.7]} {Human: ENSG00000074181, NOTCH3, notch 3, [Score=86.3, Expect=7e-17]} {Mouse: ENSMUSG00000038146, Notch3, notch 3, [Score=82.4, Expect=7e-16]} {Dmel: FBgn0051665, wry, weary, [Score=95.5, Expect=3e-20]} {Celegans: WBGene00001609, glp-1, [Score=74.7, Expect=9e-14]} {Smed: dd_Smed_v6_6929_0_1, dd_Smed_v6_6929_0_1, [Score=115, Expect=1e-27]} {RNA1509_21381} {RNA1310_11756, RNA1509_21381} {RNA1509_21381, RNA815_17372.1}
99. MligTC455_15624 376 7.83 Mlig455_004625

Neo: -

Age: -

 0.974 - - - 0.974 - - Mlig455_004625 {REF} {Length: 1661} {Pfam: Mini-chromosome maintenance protein 2 [PF12619.10, score=26.4]} {RNA1509_6364} {RNA1310_14599} {RNA815_5331}
100. MligTC455_29024 2325 48.43 Mlig455_051078

Neo: Irradiation

Age: Up-Down-Down

 0.974 - - - 0.974 - - Mlig455_051078 {REF} {Length: 906} {RNA1509_5369} {RNA1310_10116.1} {RNA815_54294}

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