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Results for MligTC455_51263

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_51263 260 5.42 Mlig455_054142

Neo: -

Age: Down-Up-Down

STRAP Mlig455_054142 {REF} {Length: 1865} {Pfam: WD domain, G-beta repeat [PF00400.34, score=75.5]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.5]} {Human: ENSG00000023734, STRAP, serine/threonine kinase receptor associated protein, [Score=253, Expect=7e-82]} {Mouse: ENSMUSG00000030224, Strap, serine/threonine kinase receptor associated protein, [Score=253, Expect=4e-82]} {Dmel: FBgn0034876, wmd, wing morphogenesis defect, [Score=292, Expect=4e-98]} {Celegans: WBGene00001232, eif-3.I, Eukaryotic translation initiation factor 3 subunit I, [Score=74.3, Expect=7e-15]} {Smed: dd_Smed_v6_4502_0_1, dd_Smed_v6_4502_0_1, [Score=249, Expect=3e-81]} {RNA1509_35607} {RNA1310_16941.1} {RNA815_9660.1}

Cumulative graph for MligTC455_51263

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.201 2.708 0.86849 1.00000
RegionR2 0.04 2.708 0.95102 1.00000
RegionR3 0.088 2.708 0.87626 1.00000
RegionR4 -0.915 2.708 0.15630 0.41071
RegionR5 -0.315 2.708 0.52406 0.88710
RegionR6 0.584 2.708 0.29519 0.88658
RegionR7 0.543 2.708 0.44207 1.00000
RegionR8 0.178 2.708 0.84249 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.354 2.708 0.88443 1.00000
RegenerationR2 0.361 2.708 0.59503 0.91325
RegenerationR3 0.148 2.708 0.82993 0.99084
RegenerationR4 -0.108 2.708 0.87911 1.00000
RegenerationR5 0.002 2.708 0.99383 1.00000
RegenerationR6 -0.359 2.708 0.60328 0.87012
RegenerationBL -0.229 2.708 0.80176 1.00000
RegenerationTP -1.469 2.708 0.18022 0.61574


Genes with expression patterns similar to MligTC455_51263

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_51263 260 5.42 Mlig455_054142

Neo: -

Age: Down-Up-Down

STRAP 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_054142 {REF} {Length: 1865} {Pfam: WD domain, G-beta repeat [PF00400.34, score=75.5]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.5]} {Human: ENSG00000023734, STRAP, serine/threonine kinase receptor associated protein, [Score=253, Expect=7e-82]} {Mouse: ENSMUSG00000030224, Strap, serine/threonine kinase receptor associated protein, [Score=253, Expect=4e-82]} {Dmel: FBgn0034876, wmd, wing morphogenesis defect, [Score=292, Expect=4e-98]} {Celegans: WBGene00001232, eif-3.I, Eukaryotic translation initiation factor 3 subunit I, [Score=74.3, Expect=7e-15]} {Smed: dd_Smed_v6_4502_0_1, dd_Smed_v6_4502_0_1, [Score=249, Expect=3e-81]} {RNA1509_35607} {RNA1310_16941.1} {RNA815_9660.1}
2. MligTC455_15895 226 4.71 Mlig455_064442

Neo: -

Age: Down-Up-Up

RABGGTB 2.583 - - - 0.957 0.701 0.925 Mlig455_064442 {REF} {Length: 1470} {TRANSSPLICED} {Pfam: Prenyltransferase and squalene oxidase repeat [PF00432.23, score=184.4]; Squalene-hopene cyclase N-terminal domain [PF13249.8, score=19.3]} {Human: ENSG00000137955, RABGGTB, Rab geranylgeranyltransferase subunit beta, [RH, Score=384, Expect=2e-133]} {Mouse: ENSMUSG00000038975, Rabggtb, Rab geranylgeranyl transferase, b subunit, [RH, Score=374, Expect=9e-130]} {Dmel: FBgn0028970, betaggt-II, beta subunit of type II geranylgeranyl transferase, [RH, Score=362, Expect=5e-125]} {Celegans: WBGene00015099, ggtb-1, Probable geranylgeranyl transferase type-2 subunit beta, [RH, Score=364, Expect=7e-126]} {Smed: dd_Smed_v6_3769_0_1, dd_Smed_v6_3769_0_1, [RH, Score=343, Expect=1e-117]} {RNA1509_27970} {RNA1310_22063, RNA1509_27970} {RNA1509_27970, RNA815_29569}
3. MligTC455_50724 402 8.37 Mlig455_007823

Neo: -

Age: -

Region-enriched R5: 1.057/0.03844

NRBP1 2.578 0.776 - - 0.958 0.844 - Mlig455_007823 {REF} {Length: 5624} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=66.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=37.5]} {Human: ENSG00000115216, NRBP1, nuclear receptor binding protein 1, [RH, Score=188, Expect=4e-50]} {Mouse: ENSMUSG00000029148, Nrbp1, nuclear receptor binding protein 1, [RH, Score=184, Expect=6e-49]} {Dmel: FBgn0027497, Madm, MLF1-adaptor molecule, [RH, Score=153, Expect=4e-38]} {Celegans: WBGene00010427, hpo-11, [RH, Score=169, Expect=1e-43]} {Smed: dd_Smed_v6_5859_0_1, dd_Smed_v6_5859_0_1, [RH, Score=199, Expect=3e-52]} {RNA1509_18578, RNA1509_19619, RNA1509_33489} {RNA1310_6856, RNA1509_18578, RNA1509_19619, RNA1509_33489} {RNA1509_18578, RNA1509_19619, RNA1509_33489, RNA815_11040}
4. MligTC455_26797 367 7.65 Mlig455_012283

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.991/0.01221

2.554 - - - 0.971 0.717 0.866 Mlig455_012283 {REF} {Length: 2040} {TRANSSPLICED} {Pfam: SET domain [PF00856.30, score=33.8]} {Smed: dd_Smed_v6_13830_0_1, dd_Smed_v6_13830_0_1, [RH, Score=75.1, Expect=1e-14]} {RNA1509_35088} {RNA1310_24589.2} {RNA815_9608}
5. MligTC455_41901 858 17.87 Mlig455_016724

Neo: -

Age: Up-Down-Up

UFL1 2.494 0.795 - - 0.967 0.732 - Mlig455_016724 {REF} {Length: 2775} {TRANSSPLICED} {Pfam: E3 UFM1-protein ligase 1 [PF09743.11, score=290.7]; Winged helix-turn-helix DNA-binding [PF13412.8, score=21.7]} {Human: ENSG00000014123, UFL1, UFM1 specific ligase 1, [RH, Score=322, Expect=9e-98]} {Mouse: ENSMUSG00000040359, Ufl1, UFM1 specific ligase 1, [RH, Score=316, Expect=9e-96]} {Dmel: FBgn0037467, Ufl1, UFM1 specific ligase 1, [RH, Score=270, Expect=1e-78]} {Celegans: WBGene00015555, ufl-1, E3 UFM1-protein ligase 1 homolog, [RH, Score=162, Expect=2e-41]} {Smed: dd_Smed_v6_5571_1_1, dd_Smed_v6_5571_1_1, [RH, Score=338, Expect=3e-104]} {RNA1509_6918} {RNA1310_6721.1, RNA1509_6918} {RNA1509_6918, RNA815_2135}
6. MligTC455_48055 271 5.65 Mlig455_059256

Neo: -

Age: -

2.427 0.727 - - 0.969 0.731 - Mlig455_059256 {REF} {Length: 4894} {Pfam: PX domain [PF00787.26, score=33.5]} {RNA1509_29567, RNA1509_47008} {RNA1310_1542.1, RNA1509_47008} {RNA1509_47008, RNA815_21449}
7. MligTC455_45410 457 9.52 Mlig455_021310

Neo: Int S/G2/M

Age: Up-Down-Down

ADSS 1.923 - - - 0.948 - 0.975 Mlig455_021310 {REF} {Length: 5161} {TRANSSPLICED} {Pfam: Adenylosuccinate synthetase [PF00709.23, score=566.8]} {Human: ENSG00000035687, ADSS, adenylosuccinate synthase, [RH, Score=503, Expect=2e-176]; ENSG00000185100, ADSSL1, adenylosuccinate synthase like 1, [RH, Score=494, Expect=4e-173]} {Mouse: ENSMUSG00000015961, Adss, adenylosuccinate synthetase, non muscle, [RH, Score=504, Expect=2e-177]; ENSMUSG00000011148, Adssl1, adenylosuccinate synthetase like 1, [RH, Score=498, Expect=1e-174]} {Dmel: FBgn0027493, AdSS, Adenylosuccinate Synthetase, [RH, Score=470, Expect=5e-164]} {Celegans: WBGene00016509, adss-1, Adenylosuccinate synthetase, [RH, Score=431, Expect=8e-149]} {Smed: dd_Smed_v6_2154_0_1, dd_Smed_v6_2154_0_1, [RH, Score=504, Expect=9e-178]} {RNA1509_22607, RNA1509_31750, RNA1509_8269} {RNA1310_16344, RNA1509_22607, RNA1509_31750, RNA1509_8269} {RNA1509_22607, RNA1509_31750, RNA1509_8269, RNA815_7491}
8. MligTC455_18882 322 6.71 Mlig455_067755

Neo: -

Age: -

1.915 - - - 0.969 - 0.946 Mlig455_067755 {REF} {Length: 2949} {Pfam: TIR domain [PF13676.8, score=89.7]; TIR domain [PF01582.22, score=43.6]} {Smed: dd_Smed_v6_9201_0_1, dd_Smed_v6_9201_0_1, [RH, Score=303, Expect=2e-90]} {RNA1509_17089} {RNA1310_6087.1} {RNA815_12761}
9. MligTC455_16678 261 5.44 Mlig455_044612

Neo: -

Age: -

CLEC16A 1.896 - - - 0.970 - 0.926 Mlig455_044612 {REF} {Length: 4709} {TRANSSPLICED} {Pfam: CLEC16A C-terminal [PF19439.1, score=339.5]; Uncharacterised conserved protein [PF09758.11, score=193.7]} {Human: ENSG00000038532, CLEC16A, C-type lectin domain containing 16A, [Score=641, Expect=0.0]} {Mouse: ENSMUSG00000068663, Clec16a, C-type lectin domain family 16, member A, [Score=647, Expect=0.0]} {Dmel: FBgn0038427, ema, endosomal maturation defective, [Score=620, Expect=0.0]} {Celegans: WBGene00001660, gop-1, Protein CLEC16A homolog, [RH, Score=303, Expect=5e-89]} {Smed: dd_Smed_v6_3621_0_1, dd_Smed_v6_3621_0_1, [Score=375, Expect=2e-115]} {RNA1509_38257, RNA1509_59719} {RNA1310_6097.1, RNA1509_38257, RNA1509_59719} {RNA1509_38257, RNA1509_59719, RNA815_1666}
10. MligTC455_28814 310 6.45 Mlig455_010429

Neo: -

Age: Up-Down-Down

Regeneration-upregulated BL: 5.256

Regeneration-enriched BL: 5.256

SETMAR 1.877 - - - 0.961 - 0.916 Mlig455_010429 {REF} {Length: 4918} {Pfam: Transposase (partial DDE domain) [PF01359.20, score=69.5]; DDE superfamily endonuclease [PF13358.8, score=43.8]; Homeodomain-like domain [PF13565.8, score=38.9]; Homeodomain-like domain [PF13384.8, score=34.8]; HTH domain in Mos1 transposase [PF17906.3, score=32.5]; Winged helix-turn-helix DNA-binding [PF13412.8, score=31.7]; Winged helix-turn helix [PF13551.8, score=25.4]; AsnC-type helix-turn-helix domain [PF13404.8, score=25.1]; Helix-turn-helix domain [PF13518.8, score=23.7]; IclR helix-turn-helix domain [PF09339.12, score=23.2]} {Human: ENSG00000170364, SETMAR, SET domain and mariner transposase fusion gene, [Score=172, Expect=6e-48]} {Smed: dd_Smed_v6_13618_0_23, dd_Smed_v6_13618_0_23, [Score=70.9, Expect=5e-15]} {RNA1509_44661} {RNA1310_12769.1} {RNA815_30119}
11. MligTC455_39622 339 7.06 Mlig455_006332

Neo: -

Age: -

FAM91A1 1.859 - - - 0.953 - 0.906 Mlig455_006332 {REF} {Length: 4161} {TRANSSPLICED} {Pfam: FAM91 C-terminus [PF14648.8, score=404.1]; FAM91 N-terminus [PF14647.8, score=395.5]} {Human: ENSG00000176853, FAM91A1, family with sequence similarity 91 member A1, [RH, Score=667, Expect=0.0]} {Mouse: ENSMUSG00000037119, Fam91a1, family with sequence similarity 91, member A1, [RH, Score=674, Expect=0.0]; ENSMUSG00000116351, Fam91a1, family with sequence similarity 91, member A1, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0064766, CG7600, [RH, Score=432, Expect=7e-138]} {Celegans: WBGene00009366, F33H2.2, [RH, Score=479, Expect=1e-157]} {Smed: dd_Smed_v6_2471_0_1, dd_Smed_v6_2471_0_1, [RH, Score=310, Expect=2e-92]} {RNA1509_26276} {RNA1310_3146} {RNA815_1984}
12. MligTC455_52010 453 9.44 Mlig455_027970

Neo: Irradiation

Age: Up-Down-Down

Region-enriched R4: 1.597/0.00358

ADAM9 1.859 - - - 0.961 - 0.898 Mlig455_027970 {REF} {Length: 4574} {Pfam: Disintegrin [PF00200.25, score=114.6]; Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=92.6]; Metallo-peptidase family M12 [PF13688.8, score=36.4]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=30.8]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=30.2]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=19.2]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=123, Expect=2e-28]} {Mouse: ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [Score=130, Expect=2e-30]} {Dmel: FBgn0265140, Meltrin, [Score=138, Expect=6e-33]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=126, Expect=2e-29]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=132, Expect=3e-31]} {RNA1509_21270} {RNA1310_13413} {RNA815_11284.1}
13. MligTC455_19451 122 2.54 Mlig455_041592

Neo: -

Age: -

Regeneration-upregulated R2: 5.256

Regeneration-enriched R2: 5.256

1.834 - - - 0.960 - 0.874 Mlig455_041592 {REF} {Length: 1456} {NoTransDecoderORF} {RNA1509_46649} {RNA1310_50665} {RNA815_51140}
14. MligTC455_17505 844 17.58 Mlig455_015141

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=1.515

Region-enriched R4: 1.911/0.01373

1.833 - - - 0.967 - 0.866 Mlig455_015141 {REF} {Length: 2900} {TRANSSPLICED} {RNA1509_40438, RNA1509_53510} {RNA1310_5427, RNA1509_40438} {RNA1509_40438, RNA815_2140.1}
15. MligTC455_30835 337 7.02 Mlig455_058095

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.267

HDAC11 1.831 - - - 0.967 0.864 - Mlig455_058095 {REF} {Length: 2115} {TRANSSPLICED} {Pfam: Histone deacetylase domain [PF00850.21, score=164.2]} {Human: ENSG00000163517, HDAC11, histone deacetylase 11, [RH, Score=412, Expect=5e-144]} {Mouse: ENSMUSG00000034245, Hdac11, histone deacetylase 11, [RH, Score=411, Expect=1e-143]} {Dmel: FBgn0051119, HDAC11, Histone deacetylase 11, [RH, Score=325, Expect=6e-110]} {Celegans: WBGene00007953, hda-11, Histone DeAcetylase, [RH, Score=291, Expect=4e-97]} {Smed: dd_Smed_v6_3401_0_4, dd_Smed_v6_3401_0_4, [RH, Score=320, Expect=1e-108]} {RNA1509_25531} {RNA1310_11718} {RNA815_3768.1}
16. MligTC455_31980 220 4.59 Mlig455_007685, Mlig455_020875

Neo: -

Age: Up-Down-Up

DIS3L2 1.829 - - - 0.962 - 0.867

Mlig455_007685 {REF} {Length: 2832} {TRANSSPLICED} {Pfam: RNB domain [PF00773.21, score=281.5]; DIS3-like exonuclease 2 C terminal [PF17877.3, score=37.2]; Dis3-like cold-shock domain 2 (CSD2) [PF17849.3, score=37.1]; Rrp44-like cold shock domain [PF17216.5, score=27.4]} {Human: ENSG00000144535, DIS3L2, DIS3 like 3'-5' exoribonuclease 2, [Score=375, Expect=3e-116]} {Mouse: ENSMUSG00000053333, Dis3l2, DIS3 like 3'-5' exoribonuclease 2, [Score=380, Expect=1e-118]} {Dmel: FBgn0035111, Dis3l2, Dis3 like 3'-5' exoribonuclease 2, [Score=264, Expect=9e-75]} {Celegans: WBGene00018612, disl-2, DIS3-like exonuclease 2, [Score=335, Expect=3e-102]} {Smed: dd_Smed_v6_7044_0_1, dd_Smed_v6_7044_0_1, [Score=349, Expect=2e-107]} {RNA1509_57497} {RNA1310_4374.2} {RNA815_1234.1}

Mlig455_020875 {REF} {Length: 1339} {Pfam: DIS3-like exonuclease 2 C terminal [PF17877.3, score=38.1]} {Human: ENSG00000144535, DIS3L2, DIS3 like 3'-5' exoribonuclease 2, [Score=53.9, Expect=7e-08]} {Mouse: ENSMUSG00000053333, Dis3l2, DIS3 like 3'-5' exoribonuclease 2, [Score=53.1, Expect=9e-08]} {Celegans: WBGene00018612, disl-2, DIS3-like exonuclease 2, [Score=49.7, Expect=6e-07]} {Smed: dd_Smed_v6_7044_0_1, dd_Smed_v6_7044_0_1, [Score=69.3, Expect=1e-13]} {RNA1509_57497} {RNA1310_47825} {RNA815_1234.1}
17. MligTC455_29507 477 9.93 Mlig455_061492

Neo: -

Age: -

SZT2 1.822 0.853 - - 0.969 - - Mlig455_061492 {REF} {Length: 14726} {TRANSSPLICED} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=111.5]} {Human: ENSG00000198198, SZT2, SZT2, KICSTOR complex subunit, [RH, Score=318, Expect=1e-85]} {Mouse: ENSMUSG00000033253, Szt2, seizure threshold 2, [RH, Score=330, Expect=1e-89]} {Dmel: FBgn0003326, sca, scabrous, [Score=98.2, Expect=1e-19]} {Celegans: WBGene00010013, F54B3.1, [RH, Score=117, Expect=2e-25]} {Smed: dd_Smed_v6_8946_0_1, dd_Smed_v6_8946_0_1, [Score=111, Expect=1e-23]} {RNA1509_25909} {RNA1310_92.1} {RNA815_13061}
18. MligTC455_17489 357 7.44 Mlig455_057590

Neo: -

Age: Up-Down-Down

ARHGEF7 1.817 - - - 0.967 0.850 - Mlig455_057590 {REF} {Length: 5348} {TRANSSPLICED} {Pfam: Variant SH3 domain [PF14604.8, score=57.8]; SH3 domain [PF00018.30, score=53.0]; Variant SH3 domain [PF07653.19, score=49.3]; RhoGEF domain [PF00621.22, score=34.9]; Unstructured region two on RhoGEF 6 and 7 [PF16614.7, score=27.8]} {Human: ENSG00000102606, ARHGEF7, Rho guanine nucleotide exchange factor 7, [RH, Score=169, Expect=7e-44]} {Mouse: ENSMUSG00000031511, Arhgef7, Rho guanine nucleotide exchange factor (GEF7), [RH, Score=164, Expect=2e-42]} {Dmel: FBgn0015803, RtGEF, Rho-type guanine nucleotide exchange factor, [RH, Score=140, Expect=5e-34]} {Celegans: WBGene00010776, pix-1, PIX (PAK (p21-activated kinase) Interacting eXchange factor) homolog, [Score=103, Expect=4e-23]} {Smed: dd_Smed_v6_4423_0_1, dd_Smed_v6_4423_0_1, [RH, Score=157, Expect=2e-40]} {RNA1509_19459} {RNA1310_3287, RNA1509_19459} {RNA1509_19459, RNA815_13921}
19. MligTC455_18590 632 13.16 Mlig455_006915, Mlig455_017931

Neo: -

Age: -

Region-enriched R3: 3.002/0.00887
Region-enriched R5: 2.798/0.00397

SLC25A37 1.812 - - - 0.965 0.847 -

Mlig455_006915 {REF} {Length: 3466} {TRANSSPLICED} {Pfam: Mitochondrial carrier protein [PF00153.29, score=192.6]} {Human: ENSG00000147454, SLC25A37, solute carrier family 25 member 37, [RH, Score=321, Expect=1e-108]} {Mouse: ENSMUSG00000034248, Slc25a37, solute carrier family 25, member 37, [RH, Score=315, Expect=1e-106]; ENSMUSG00000040414, Slc25a28, solute carrier family 25, member 28, [RH, Score=305, Expect=3e-102]} {Dmel: FBgn0039561, mfrn, mitoferrin, [RH, Score=263, Expect=6e-86]} {Celegans: WBGene00012204, mfn-1, Mitoferrin, [RH, Score=257, Expect=3e-84]} {Smed: dd_Smed_v6_11061_0_1, dd_Smed_v6_11061_0_1, [RH, Score=317, Expect=5e-108]} {RNA1509_40499} {RNA1310_19207} {RNA815_13306}

Mlig455_017931 {REF} {Length: 3454} {TRANSSPLICED} {Pfam: Mitochondrial carrier protein [PF00153.29, score=192.6]} {Human: ENSG00000147454, SLC25A37, solute carrier family 25 member 37, [RH, Score=321, Expect=1e-108]} {Mouse: ENSMUSG00000034248, Slc25a37, solute carrier family 25, member 37, [RH, Score=315, Expect=1e-106]; ENSMUSG00000040414, Slc25a28, solute carrier family 25, member 28, [RH, Score=305, Expect=3e-102]} {Dmel: FBgn0039561, mfrn, mitoferrin, [RH, Score=263, Expect=6e-86]} {Celegans: WBGene00012204, mfn-1, Mitoferrin, [RH, Score=257, Expect=3e-84]} {Smed: dd_Smed_v6_11061_0_1, dd_Smed_v6_11061_0_1, [RH, Score=317, Expect=5e-108]} {RNA1509_21388, RNA1509_36168, RNA1509_40499, RNA1509_48571, RNA1509_57782} {RNA1310_19207, RNA1509_21388, RNA1509_36168, RNA1509_40499, RNA1509_48571, RNA1509_57782} {RNA1509_21388, RNA1509_36168, RNA1509_40499, RNA1509_48571, RNA1509_57782, RNA815_13306}
20. MligTC455_09141 234 4.87 Mlig455_012120

Neo: -

Age: -

1.808 - - - 0.957 - 0.851 Mlig455_012120 {REF} {Length: 1545} {RNA1310_55515} {RNA815_30023}
21. MligTC455_43440 428 8.91 Mlig455_055282

Neo: -

Age: Down-Up-Down

RNF170 1.806 - 0.828 - 0.978 - - Mlig455_055282 {REF} {Length: 1338} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF1232) [PF06803.14, score=37.1]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=31.4]; Ring finger domain [PF13639.8, score=30.6]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=29.9]; zinc-RING finger domain [PF14634.8, score=26.7]; RING-type zinc-finger [PF13445.8, score=24.3]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=23.7]; zinc finger of C3HC4-type, RING [PF15227.8, score=21.6]} {Human: ENSG00000120925, RNF170, ring finger protein 170, [RH, Score=139, Expect=1e-39]} {Mouse: ENSMUSG00000013878, Rnf170, ring finger protein 170, [RH, Score=135, Expect=2e-38]} {Smed: dd_Smed_v6_7918_0_1, dd_Smed_v6_7918_0_1, [RH, Score=126, Expect=2e-35]} {RNA1509_22235} {RNA1310_9312.1} {RNA815_10897}
22. MligTC455_39241 166 3.45 Mlig455_041934

Neo: Irradiation

Age: -

NEK2 1.803 - - - 0.959 - 0.844 Mlig455_041934 {REF} {Length: 2141} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=171.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=113.2]; Kinase-like [PF14531.8, score=26.0]; ABC1 atypical kinase-like domain [PF03109.18, score=21.0]} {Human: ENSG00000117650, NEK2, NIMA related kinase 2, [Score=287, Expect=5e-92]} {Mouse: ENSMUSG00000110797, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=278, Expect=1e-88]; ENSMUSG00000026622, Nek2, NIMA (never in mitosis gene a)-related expressed kinase 2, [Score=278, Expect=1e-88]} {Dmel: FBgn0029970, Nek2, [Score=227, Expect=2e-66]} {Celegans: WBGene00008956, nekl-3, Serine/threonine-protein kinase nekl-3, [Score=161, Expect=9e-46]} {Smed: dd_Smed_v6_8347_0_2, dd_Smed_v6_8347_0_2, [Score=162, Expect=3e-46]} {RNA1509_56527} {RNA1310_29373} {RNA815_3391.1}
23. MligTC455_22531 642 13.38 Mlig455_003820, Mlig455_019969, Mlig455_033265, Mlig455_048427, Mlig455_048495, Mlig455_048570, Mlig455_049044

Neo: -

Age: -

RAD54L 1.798 0.830 - - 0.968 - -

Mlig455_003820 {REF} {Length: 560} {Pfam: DDE superfamily endonuclease [PF13358.8, score=40.0]} {Smed: dd_Smed_v6_66824_0_1, dd_Smed_v6_66824_0_1, [Score=79.7, Expect=7e-20]} {RNA1509_20978} {RNA1310_8640} {RNA815_3193.1}

Mlig455_019969 {REF} {Length: 1046} {Pfam: Homeodomain-like domain [PF13384.8, score=50.0]; DDE superfamily endonuclease [PF13358.8, score=39.2]; Helix-turn-helix domain [PF13518.8, score=38.4]; Winged helix-turn helix [PF13551.8, score=34.3]; Homeodomain-like domain [PF13565.8, score=30.0]; Transposase [PF01498.20, score=28.3]; Winged helix-turn-helix DNA-binding [PF13412.8, score=24.9]; Helix-turn-helix [PF01381.24, score=20.4]; Helix-turn-helix domain of resolvase [PF02796.17, score=20.0]; CENP-B N-terminal DNA-binding domain [PF04218.15, score=18.1]} {Smed: dd_Smed_v6_66824_0_1, dd_Smed_v6_66824_0_1, [Score=82.4, Expect=9e-20]} {RNA1509_20978} {RNA1310_12978} {RNA815_3193.1}

Mlig455_033265 {REF} {Length: 560} {Pfam: DDE superfamily endonuclease [PF13358.8, score=39.9]} {Smed: dd_Smed_v6_66824_0_1, dd_Smed_v6_66824_0_1, [Score=82.4, Expect=5e-21]} {RNA1509_20978} {RNA1310_8640} {RNA815_3193.1}

Mlig455_048427 {REF} {Length: 872} {Pfam: DDE superfamily endonuclease [PF13358.8, score=39.6]; Homeodomain-like domain [PF13384.8, score=21.9]; Transposase [PF01498.20, score=21.2]; Helix-turn-helix [PF01381.24, score=20.9]} {Smed: dd_Smed_v6_66824_0_1, dd_Smed_v6_66824_0_1, [Score=82.4, Expect=5e-20]} {RNA1509_20978} {RNA1310_12978} {RNA815_3193.1}

Mlig455_048495 {REF} {Length: 3787} {Pfam: SNF2-related domain [PF00176.25, score=206.4]; Helicase conserved C-terminal domain [PF00271.33, score=52.6]; Homeodomain-like domain [PF13384.8, score=44.4]; Helix-turn-helix domain [PF13518.8, score=38.4]; DDE superfamily endonuclease [PF13358.8, score=36.4]; Winged helix-turn helix [PF13551.8, score=31.5]; Type III restriction enzyme, res subunit [PF04851.17, score=29.5]; Rad54 N terminal [PF08658.12, score=27.1]; Homeodomain-like domain [PF13565.8, score=25.8]; Helix-turn-helix [PF01381.24, score=23.9]; Class II histone deacetylase complex subunits 2 and 3 [PF11496.10, score=22.0]; Transposase [PF01498.20, score=20.2]} {Human: ENSG00000085999, RAD54L, RAD54 like, [RH, Score=930, Expect=0.0]} {Mouse: ENSMUSG00000028702, Rad54l, RAD54 like (S. cerevisiae), [RH, Score=931, Expect=0.0]} {Dmel: FBgn0002989, okr, okra, [RH, Score=795, Expect=0.0]} {Celegans: WBGene00004298, rad-54, [RH, Score=804, Expect=0.0]} {Smed: dd_Smed_v6_15532_0_1, dd_Smed_v6_15532_0_1, [RH, Score=947, Expect=0.0]} {RNA1509_38919} {RNA1310_7218} {RNA815_1852.1}

Mlig455_048570 {REF} {Length: 872} {Pfam: DDE superfamily endonuclease [PF13358.8, score=39.6]; Homeodomain-like domain [PF13384.8, score=21.9]; Transposase [PF01498.20, score=21.2]; Helix-turn-helix [PF01381.24, score=20.9]} {Smed: dd_Smed_v6_66824_0_1, dd_Smed_v6_66824_0_1, [Score=82.4, Expect=5e-20]} {RNA1509_20978} {RNA1310_12978} {RNA815_3193.1}

Mlig455_049044 {REF} {Length: 965} {Pfam: DDE superfamily endonuclease [PF13358.8, score=37.0]; Homeodomain-like domain [PF13384.8, score=21.1]} {Smed: dd_Smed_v6_66824_0_1, dd_Smed_v6_66824_0_1, [Score=82.8, Expect=6e-20]} {RNA1509_20978} {RNA1310_12978} {RNA815_3193.1}
24. MligTC455_50791 850 17.7 Mlig455_049295

Neo: -

Age: -

1.796 - - - 0.974 - 0.822 Mlig455_049295 {REF} {Length: 1117} {TRANSSPLICED} {RNA1509_20394, RNA1509_34054} {RNA1310_29625, RNA1509_20394} {RNA1509_20394, RNA815_17224}
25. MligTC455_39605 496 10.34 Mlig455_062588

Neo: -

Age: -

CASP3 1.794 - - - 0.952 - 0.842 Mlig455_062588 {REF} {Length: 2819} {TRANSSPLICED} {Pfam: Caspase domain [PF00656.24, score=128.5]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=207, Expect=1e-65]; ENSG00000165806, CASP7, caspase 7, [Score=205, Expect=9e-65]} {Mouse: ENSMUSG00000025076, Casp7, caspase 7, [Score=210, Expect=1e-66]; ENSMUSG00000031628, Casp3, caspase 3, [Score=206, Expect=4e-65]} {Dmel: FBgn0010501, Dcp-1, Death caspase-1, [Score=184, Expect=2e-56]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=108, Expect=5e-28]} {Smed: dd_Smed_v6_3121_1_1, dd_Smed_v6_3121_1_1, [Score=160, Expect=7e-48]} {RNA1509_15108, RNA1509_45726} {RNA1310_29553, RNA1509_15108, RNA1509_45726} {RNA1509_15108, RNA1509_45726, RNA815_13205.1}
26. MligTC455_47301 209 4.35 Mlig455_049133

Neo: -

Age: -

ASXL2 1.79 - - - 0.963 - 0.827 Mlig455_049133 {REF} {Length: 3735} {TRANSSPLICED} {Pfam: Asx homology domain [PF13919.8, score=57.7]} {Human: ENSG00000143970, ASXL2, ASXL transcriptional regulator 2, [RH, Score=82.8, Expect=1e-15]} {Mouse: ENSMUSG00000037486, Asxl2, additional sex combs like 2, transcriptional regulator, [RH, Score=78.6, Expect=6e-15]} {Smed: dd_Smed_v6_8139_0_1, dd_Smed_v6_8139_0_1, [Score=52.4, Expect=1e-06]} {RNA1509_12997} {RNA1310_6363, RNA1509_12997} {RNA1509_12997, RNA815_24627.1}
27. MligTC455_44425 460 9.58 Mlig455_041704

Neo: -

Age: -

IPO11 1.784 - - - 0.969 - 0.815 Mlig455_041704 {REF} {Length: 4130} {TRANSSPLICED} {Pfam: Importin-beta N-terminal domain [PF03810.21, score=40.5]} {Human: ENSG00000086200, IPO11, importin 11, [RH, Score=132, Expect=1e-30]} {Mouse: ENSMUSG00000042590, Ipo11, importin 11, [RH, Score=132, Expect=5e-31]} {Dmel: FBgn0284254, Impbeta11, Importin beta11, [RH, Score=96.7, Expect=5e-20]} {RNA1509_12338} {RNA1310_4949.1} {RNA815_1982}
28. MligTC455_29503 492 10.25 Mlig455_059808

Neo: -

Age: -

SZT2 1.779 0.810 - - 0.969 - - Mlig455_059808 {REF} {Length: 13680} {TRANSSPLICED} {Human: ENSG00000198198, SZT2, SZT2, KICSTOR complex subunit, [RH, Score=325, Expect=9e-88]} {Mouse: ENSMUSG00000033253, Szt2, seizure threshold 2, [RH, Score=330, Expect=1e-89]} {Celegans: WBGene00010013, F54B3.1, [RH, Score=112, Expect=7e-24]} {Smed: dd_Smed_v6_8946_0_1, dd_Smed_v6_8946_0_1, [Score=111, Expect=1e-23]} {RNA1509_25909, RNA1509_3648} {RNA1310_92.1, RNA1509_25909, RNA1509_3648} {RNA1509_25909, RNA1509_3648, RNA815_12089}
29. MligTC455_53266 513 10.68 Mlig455_012374

Neo: Irradiation

Age: -

Region-enriched R5: 1.494/0.00168

CDC5L 1.779 - - - 0.970 - 0.809 Mlig455_012374 {REF} {Length: 3840} {Pfam: pre-mRNA splicing factor component [PF11831.10, score=115.1]; Myb-like DNA-binding domain [PF00249.33, score=75.5]; Myb-like DNA-binding domain [PF13921.8, score=66.3]} {Human: ENSG00000096401, CDC5L, cell division cycle 5 like, [RH, Score=426, Expect=5e-138]} {Mouse: ENSMUSG00000023932, Cdc5l, cell division cycle 5-like (S. pombe), [RH, Score=425, Expect=7e-138]; ENSMUSG00000112027, Gm9045, predicted gene 9045, [RH, Score=422, Expect=8e-137]; ENSMUSG00000112814, Gm9040, predicted gene 9040, [RH, Score=422, Expect=7e-137]; ENSMUSG00000112919, Gm9049, predicted gene 9049, [RH, Score=422, Expect=8e-137]; ENSMUSG00000112216, Gm32717, predicted gene, 32717, [RH, Score=422, Expect=6e-137]; ENSMUSG00000112252, Gm32802, predicted gene, 32802, [RH, Score=422, Expect=6e-137]; ENSMUSG00000112419, Gm9044, predicted gene 9044, [RH, Score=422, Expect=7e-137]; ENSMUSG00000112495, Gm9048, predicted gene 9048, [RH, Score=418, Expect=3e-135]; ENSMUSG00000112781, Gm9046, predicted gene 9046, [RH, Score=418, Expect=3e-135]} {Dmel: FBgn0265574, Cdc5, Cell division cycle 5, [RH, Score=415, Expect=4e-134]} {Celegans: WBGene00008386, cdc-5L, Cell Division Cycle related, [RH, Score=484, Expect=6e-162]} {Smed: dd_Smed_v6_4163_0_1, dd_Smed_v6_4163_0_1, [RH, Score=308, Expect=8e-94]} {RNA1509_27632, RNA1509_41420, RNA1509_48943, RNA1509_52253, RNA1509_6311} {RNA1310_5017, RNA1509_27632, RNA1509_41420, RNA1509_48943, RNA1509_52253, RNA1509_6311} {RNA1509_27632, RNA1509_41420, RNA1509_48943, RNA1509_52253, RNA1509_6311, RNA815_11513}
30. MligTC455_33586 377 7.86 Mlig455_049738

Neo: -

Age: -

1.778 - - - 0.961 - 0.817 Mlig455_049738 {REF} {Length: 1287} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_36664} {RNA1310_55820} {RNA815_13552}
31. MligTC455_47937 1817 37.85 Mlig455_007819

Neo: -

Age: -

LYPLA2 1.778 0.808 - - 0.970 - - Mlig455_007819 {REF} {Length: 1709} {Pfam: Phospholipase/Carboxylesterase [PF02230.18, score=237.8]; Alpha/beta hydrolase family [PF12697.9, score=25.2]; Serine aminopeptidase, S33 [PF12146.10, score=23.4]; alpha/beta hydrolase fold [PF07859.15, score=21.7]; Prolyl oligopeptidase family [PF00326.23, score=21.6]; Dienelactone hydrolase family [PF01738.20, score=21.3]} {Human: ENSG00000011009, LYPLA2, lysophospholipase II, [RH, Score=214, Expect=1e-69]; ENSG00000120992, LYPLA1, lysophospholipase I, [RH, Score=211, Expect=2e-68]} {Mouse: ENSMUSG00000025903, Lypla1, lysophospholipase 1, [RH, Score=216, Expect=2e-70]; ENSMUSG00000028670, Lypla2, lysophospholipase 2, [RH, Score=214, Expect=6e-70]} {Dmel: FBgn0042138, CG18815, [RH, Score=216, Expect=5e-71]} {Celegans: WBGene00010564, ath-1, Acyl protein THioesterase family, [RH, Score=194, Expect=4e-62]} {Smed: dd_Smed_v6_638_0_1, dd_Smed_v6_638_0_1, [RH, Score=218, Expect=2e-71]} {RNA1509_20687, RNA1509_23013} {RNA1310_28247, RNA1509_20687, RNA1509_23013} {RNA1509_20687, RNA1509_23013, RNA815_12780}
32. MligTC455_33587 801 16.69 Mlig455_005023, Mlig455_005476, Mlig455_050755

Neo: -

Age: -

1.775 - - - 0.960 - 0.815

Mlig455_005023 {REF} {Length: 1011} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_36664} {RNA1310_27466.1} {RNA815_13552}

Mlig455_005476 {REF} {Length: 348} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_36664} {RNA1310_55820} {RNA815_13552}

Mlig455_050755 {REF} {Length: 1599} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_36664} {RNA1310_27466.1} {RNA815_13552}
33. MligTC455_38871 267 5.56 Mlig455_044804

Neo: -

Age: -

LEMD3 1.742 - - - 0.977 0.765 - Mlig455_044804 {REF} {Length: 5081} {Pfam: LEM domain [PF03020.17, score=34.4]} {Human: ENSG00000174106, LEMD3, LEM domain containing 3, [RH, Score=74.7, Expect=4e-13]} {Mouse: ENSMUSG00000048661, Lemd3, LEM domain containing 3, [RH, Score=76.3, Expect=7e-14]} {Dmel: FBgn0034962, MAN1, [RH, Score=60.8, Expect=3e-09]} {Smed: dd_Smed_v6_3626_0_1, dd_Smed_v6_3626_0_1, [RH, Score=77.4, Expect=1e-14]} {RNA1509_37408, RNA1509_55130} {RNA1310_3531, RNA1509_37408, RNA1509_55130} {RNA1509_37408, RNA1509_55130, RNA815_1027.1}
34. MligTC455_41900 1108 23.08 Mlig455_016657

Neo: -

Age: -

UFL1 1.735 0.753 - - 0.982 - - Mlig455_016657 {REF} {Length: 2725} {TRANSSPLICED} {Pfam: E3 UFM1-protein ligase 1 [PF09743.11, score=290.7]; Winged helix-turn-helix DNA-binding [PF13412.8, score=21.7]} {Human: ENSG00000014123, UFL1, UFM1 specific ligase 1, [RH, Score=322, Expect=9e-98]} {Mouse: ENSMUSG00000040359, Ufl1, UFM1 specific ligase 1, [RH, Score=316, Expect=9e-96]} {Dmel: FBgn0037467, Ufl1, UFM1 specific ligase 1, [RH, Score=270, Expect=1e-78]} {Celegans: WBGene00015555, ufl-1, E3 UFM1-protein ligase 1 homolog, [RH, Score=162, Expect=2e-41]} {Smed: dd_Smed_v6_5571_1_1, dd_Smed_v6_5571_1_1, [RH, Score=338, Expect=3e-104]} {RNA1509_6918} {RNA1310_6721.1} {RNA815_2135}
35. MligTC455_22694 319 6.65 Mlig455_065144

Neo: -

Age: -

Region-enriched R5: 2.124/0.00776

ABI1 1.721 - - - 0.961 0.760 - Mlig455_065144 {REF} {Length: 5109} {TRANSSPLICED} {Pfam: Variant SH3 domain [PF14604.8, score=61.1]; SH3 domain [PF00018.30, score=56.4]; Abl-interactor HHR [PF07815.16, score=52.1]; Variant SH3 domain [PF07653.19, score=45.3]} {Human: ENSG00000136754, ABI1, abl interactor 1, [RH, Score=129, Expect=5e-32]; ENSG00000138443, ABI2, abl interactor 2, [RH, Score=127, Expect=2e-31]} {Mouse: ENSMUSG00000026782, Abi2, abl-interactor 2, [RH, Score=130, Expect=7e-33]; ENSMUSG00000058835, Abi1, abl-interactor 1, [RH, Score=128, Expect=4e-32]} {Dmel: FBgn0020510, Abi, Abelson interacting protein, [RH, Score=115, Expect=1e-27]} {Celegans: WBGene00015146, abi-1, ABl Interactor homolog, [RH, Score=116, Expect=4e-28]} {Smed: dd_Smed_v6_690_0_1, dd_Smed_v6_690_0_1, [RH, Score=104, Expect=7e-26]} {RNA1509_22931} {RNA1310_20258, RNA1509_22931} {RNA1509_22931, RNA815_20423}
36. MligTC455_38664 290 6.05 Mlig455_052362

Neo: Irradiation

Age: -

Region-enriched R5: 1.345/0.01260

SLC4A1AP 1.717 0.755 - - 0.962 - - Mlig455_052362 {REF} {Length: 3656} {Pfam: FHA domain [PF00498.28, score=67.1]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=24.7]; Dicer dimerisation domain [PF03368.16, score=21.2]} {Human: ENSG00000163798, SLC4A1AP, solute carrier family 4 member 1 adaptor protein, [RH, Score=262, Expect=6e-76]} {Mouse: ENSMUSG00000029141, Slc4a1ap, solute carrier family 4 (anion exchanger), member 1, adaptor protein, [RH, Score=252, Expect=2e-72]} {Dmel: FBgn0038640, CG7706, [RH, Score=224, Expect=8e-63]} {Celegans: WBGene00014011, ZK632.2, [RH, Score=169, Expect=8e-44]} {Smed: dd_Smed_v6_8435_0_1, dd_Smed_v6_8435_0_1, [Score=273, Expect=5e-82]} {RNA1509_15385, RNA1509_36632, RNA1509_37617, RNA1509_58889} {RNA1310_8436, RNA1509_15385, RNA1509_36632, RNA1509_37617, RNA1509_58889} {RNA1509_15385, RNA1509_36632, RNA1509_37617, RNA1509_58889, RNA815_10628}
37. MligTC455_46205 443 9.23 Mlig455_059041

Neo: -

Age: -

THOC2 1.717 0.757 - - 0.960 - - Mlig455_059041 {REF} {Length: 5604} {TRANSSPLICED} {Pfam: Transcription factor/nuclear export subunit protein 2 [PF11262.10, score=291.6]; THO complex subunit 2 N-terminus [PF16134.7, score=251.2]; Transcription- and export-related complex subunit [PF11732.10, score=78.2]} {Human: ENSG00000125676, THOC2, THO complex 2, [RH, Score=776, Expect=0.0]} {Mouse: ENSMUSG00000079065, BC005561, cDNA sequence BC005561, [RH, Score=788, Expect=0.0]; ENSMUSG00000037475, Thoc2, THO complex 2, [RH, Score=774, Expect=0.0]} {Dmel: FBgn0031390, tho2, [RH, Score=704, Expect=0.0]} {Celegans: WBGene00015813, thoc-2, THO Complex (Transcription factor/nuclear export) subunit, [RH, Score=549, Expect=1e-170]} {Smed: dd_Smed_v6_3159_0_2, dd_Smed_v6_3159_0_2, [RH, Score=768, Expect=0.0]} {RNA1509_3180, RNA1509_45099} {RNA1310_1726, RNA1509_3180, RNA1509_45099} {RNA1509_3180, RNA1509_45099, RNA815_1568}
38. MligTC455_44719 880 18.34 Mlig455_058369

Neo: -

Age: -

Region-enriched R5: 1.007/0.00562

CASP9 1.712 - - - 0.960 0.752 - Mlig455_058369 {REF} {Length: 2561} {TRANSSPLICED} {Pfam: Caspase domain [PF00656.24, score=119.2]; Caspase recruitment domain [PF00619.23, score=44.3]} {Human: ENSG00000132906, CASP9, caspase 9, [RH, Score=155, Expect=4e-42]} {Mouse: ENSMUSG00000028914, Casp9, caspase 9, [Score=153, Expect=4e-41]; ENSMUSG00000029863, Casp2, caspase 2, [Score=149, Expect=1e-39]} {Dmel: FBgn0019972, Drice, Death related ICE-like caspase, [Score=121, Expect=2e-30]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [RH, Score=169, Expect=1e-46]} {Smed: dd_Smed_v6_1167_0_1, dd_Smed_v6_1167_0_1, [Score=116, Expect=9e-30]} {RNA1509_6944} {RNA1310_8124, RNA1509_6944} {RNA1509_6944, RNA815_4074}
39. MligTC455_43388 242 5.03 Mlig455_043911

Neo: -

Age: -

TRIM67 1.71 - - - 0.955 0.755 - Mlig455_043911 {REF} {Length: 4112} {Pfam: SPRY domain [PF00622.30, score=58.2]; zinc finger of C3HC4-type, RING [PF15227.8, score=29.4]; RING-type zinc-finger [PF13445.8, score=28.6]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=26.0]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=23.2]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=21.1]} {Human: ENSG00000119283, TRIM67, tripartite motif containing 67, [Score=379, Expect=7e-121]; ENSG00000100505, TRIM9, tripartite motif containing 9, [Score=375, Expect=4e-120]} {Mouse: ENSMUSG00000036913, Trim67, tripartite motif-containing 67, [Score=381, Expect=4e-122]; ENSMUSG00000021071, Trim9, tripartite motif-containing 9, [Score=379, Expect=1e-121]} {Dmel: FBgn0051721, Trim9, Tripartite motif containing 9, [Score=366, Expect=8e-117]} {Celegans: WBGene00016539, madd-2, [Score=342, Expect=2e-107]} {Smed: dd_Smed_v6_8386_0_1, dd_Smed_v6_8386_0_1, [Score=421, Expect=5e-138]} {RNA1509_51200} {RNA1310_8407} {RNA815_30780}
40. MligTC455_07087 753 15.69 Mlig455_033003, Mlig455_044987, Mlig455_044989, Mlig455_052687

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.952

1.708 - - - 0.956 0.752 -

Mlig455_033003 {REF} {Length: 253} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944} {RNA815_10907}

Mlig455_044987 {REF} {Length: 249} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944, RNA1509_51459} {RNA1509_51459, RNA815_10907}

Mlig455_044989 {REF} {Length: 239} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944} {RNA815_10907}

Mlig455_052687 {REF} {Length: 243} {NoTransDecoderORF} {RNA1509_51459} {RNA1310_59944} {RNA815_10907}
41. MligTC455_17869 337 7.02 Mlig455_067725

Neo: Int S/G2/M

Age: -

1.705 - - - 0.977 - 0.728 Mlig455_067725 {REF} {Length: 2651} {TRANSSPLICED} {RNA1509_51335} {RNA1310_20317, RNA1509_51335} {RNA1509_51335, RNA815_19485}
42. MligTC455_35377 667 13.89 Mlig455_011402

Neo: -

Age: -

YIPF5 1.701 - - - 0.953 0.748 - Mlig455_011402 {REF} {Length: 1977} {TRANSSPLICED} {Pfam: Yip1 domain [PF04893.19, score=39.3]} {Human: ENSG00000145817, YIPF5, Yip1 domain family member 5, [RH, Score=243, Expect=5e-80]} {Mouse: ENSMUSG00000024487, Yipf5, Yip1 domain family, member 5, [RH, Score=220, Expect=5e-71]; ENSMUSG00000029158, Yipf7, Yip1 domain family, member 7, [RH, Score=220, Expect=3e-71]} {Dmel: FBgn0032465, CG12404, [RH, Score=211, Expect=1e-67]} {Celegans: WBGene00009336, F32D8.14, [RH, Score=241, Expect=1e-79]} {Smed: dd_Smed_v6_4746_0_1, dd_Smed_v6_4746_0_1, [RH, Score=242, Expect=2e-80]} {RNA1509_31414, RNA1509_6683} {RNA1310_15036, RNA1509_31414} {RNA1509_31414, RNA815_6908.1}
43. MligTC455_38264 310 6.46 Mlig455_039091

Neo: Int S/G2/M

Age: Down-Up-Down

Region-enriched R5: 1.273/0.02550

1.696 0.741 - - 0.955 - - Mlig455_039091 {REF} {Length: 3275} {TRANSSPLICED} {RNA1509_45258} {RNA1310_7145} {RNA815_4240}
44. MligTC455_29727 174 3.63 Mlig455_068586

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.327

ANKRD50 1.695 - - - 0.964 - 0.731 Mlig455_068586 {REF} {Length: 5557} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=91.7]; Ankyrin repeats (many copies) [PF13857.8, score=59.5]; Ankyrin repeats (many copies) [PF13637.8, score=59.2]; Ankyrin repeat [PF13606.8, score=43.8]; Ankyrin repeat [PF00023.32, score=39.6]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=92.4, Expect=4e-18]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=93.6, Expect=1e-18]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=78.6, Expect=3e-14]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=68.9, Expect=2e-11]} {Smed: dd_Smed_v6_6779_0_1, dd_Smed_v6_6779_0_1, [Score=89.0, Expect=2e-17]} {RNA1509_30822} {RNA1310_7480} {RNA815_932.1}
45. MligTC455_25310 708 14.75 Mlig455_011461, Mlig455_011546

Neo: -

Age: -

CCNY 1.694 - - - 0.968 0.726 -

Mlig455_011461 {REF} {Length: 3633} {TRANSSPLICED} {Pfam: Cyclin, N-terminal domain [PF00134.25, score=39.2]; Cyclin [PF08613.13, score=32.0]} {Human: ENSG00000108100, CCNY, cyclin Y, [RH, Score=261, Expect=2e-84]; ENSG00000163249, CCNYL1, cyclin Y like 1, [RH, Score=259, Expect=2e-83]} {Mouse: ENSMUSG00000024286, Ccny, cyclin Y, [RH, Score=263, Expect=4e-85]; ENSMUSG00000070871, Ccnyl1, cyclin Y-like 1, [RH, Score=256, Expect=3e-82]} {Dmel: FBgn0032378, CycY, Cyclin Y, [RH, Score=263, Expect=9e-85]} {Celegans: WBGene00022697, cyy-1, Cyclin-Y, [RH, Score=280, Expect=5e-92]} {Smed: dd_Smed_v6_8226_0_1, dd_Smed_v6_8226_0_1, [RH, Score=261, Expect=4e-84]} {RNA1509_38487, RNA1509_40005} {RNA1310_24588, RNA1509_40005} {RNA1509_40005, RNA815_24086}

Mlig455_011546 {REF} {Length: 3858} {TRANSSPLICED} {Pfam: Cyclin, N-terminal domain [PF00134.25, score=39.1]; Cyclin [PF08613.13, score=31.9]} {Human: ENSG00000108100, CCNY, cyclin Y, [Score=263, Expect=3e-85]; ENSG00000163249, CCNYL1, cyclin Y like 1, [Score=259, Expect=3e-83]} {Mouse: ENSMUSG00000024286, Ccny, cyclin Y, [Score=265, Expect=3e-86]; ENSMUSG00000070871, Ccnyl1, cyclin Y-like 1, [Score=256, Expect=5e-82]} {Dmel: FBgn0032378, CycY, Cyclin Y, [RH, Score=266, Expect=8e-86]} {Celegans: WBGene00022697, cyy-1, Cyclin-Y, [RH, Score=282, Expect=7e-93]} {Smed: dd_Smed_v6_8226_0_1, dd_Smed_v6_8226_0_1, [RH, Score=264, Expect=4e-85]} {RNA1509_38487} {RNA1310_24588, RNA1509_38487} {RNA1509_38487, RNA815_24086}
46. MligTC455_19577 522 10.88 Mlig455_052861

Neo: -

Age: -

ZNF845 1.685 0.721 - - 0.964 - - Mlig455_052861 {REF} {Length: 3297} {TRANSSPLICED} {Pfam: Zinc-finger double domain [PF13465.8, score=84.3]; Zinc finger, C2H2 type [PF00096.28, score=64.5]; C2H2-type zinc finger [PF13894.8, score=55.2]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=23.7]; Zinc finger C2H2-type, 3 repeats [PF18868.3, score=23.3]; zinc-finger C2H2-type [PF16622.7, score=21.7]} {Human: ENSG00000213799, ZNF845, zinc finger protein 845, [Score=170, Expect=2e-42]; ENSG00000159917, ZNF235, zinc finger protein 235, [Score=170, Expect=5e-43]; ENSG00000106261, ZKSCAN1, zinc finger with KRAB and SCAN domains 1, [Score=169, Expect=7e-44]; ENSG00000167380, ZNF226, zinc finger protein 226, [Score=169, Expect=1e-42]; ENSG00000198131, ZNF544, zinc finger protein 544, [Score=169, Expect=5e-43]; ENSG00000159915, ZNF233, zinc finger protein 233, [Score=168, Expect=8e-43]; ENSG00000281894, ZKSCAN7, zinc finger with KRAB and SCAN domains 7, [Score=167, Expect=4e-42]; ENSG00000196345, ZKSCAN7, zinc finger with KRAB and SCAN domains 7, [Score=167, Expect=4e-42]; ENSG00000144026, ZNF514, zinc finger protein 514, [Score=167, Expect=3e-44]; ENSG00000167766, ZNF83, zinc finger protein 83, [Score=167, Expect=2e-43]; ENSG00000062370, ZNF112, zinc finger protein 112, [Score=166, Expect=2e-41]; ENSG00000198464, ZNF480, zinc finger protein 480, [Score=166, Expect=9e-43]; ENSG00000184635, ZNF93, zinc finger protein 93, [Score=166, Expect=2e-42]; ENSG00000176371, ZSCAN2, zinc finger and SCAN domain containing 2, [Score=166, Expect=2e-42]; ENSG00000167384, ZNF180, zinc finger protein 180, [Score=164, Expect=2e-41]; ENSG00000121903, ZSCAN20, zinc finger and SCAN domain containing 20, [Score=164, Expect=1e-40]; ENSG00000141040, ZNF287, zinc finger protein 287, [Score=164, Expect=4e-41]; ENSG00000276219, ZNF676, zinc finger protein 676, [Score=164, Expect=7e-42]; ENSG00000170949, ZNF160, zinc finger protein 160, [Score=163, Expect=1e-40]; ENSG00000249459, ZNF286B, zinc finger protein 286B, [Score=163, Expect=7e-42]; ENSG00000186017, ZNF566, zinc finger protein 566, [Score=163, Expect=7e-43]; ENSG00000197497, ZNF665, zinc finger protein 665, [Score=163, Expect=5e-41]; ENSG00000136866, ZFP37, ZFP37 zinc finger protein, [Score=162, Expect=6e-41]; ENSG00000182318, ZSCAN22, zinc finger and SCAN domain containing 22, [Score=162, Expect=4e-42]; ENSG00000198315, ZKSCAN8, zinc finger with KRAB and SCAN domains 8, [Score=162, Expect=2e-41]; ENSG00000198346, ZNF813, zinc finger protein 813, [Score=162, Expect=3e-41]; ENSG00000184939, ZFP90, ZFP90 zinc finger protein, [Score=162, Expect=6e-41]; ENSG00000198816, ZNF358, zinc finger protein 358, [Score=162, Expect=3e-41]; ENSG00000269067, ZNF728, zinc finger protein 728, [Score=162, Expect=6e-41]} {Mouse: ENSMUSG00000060630, Zfp735, zinc finger protein 735, [Score=181, Expect=5e-47]; ENSMUSG00000078868, Gm14412, predicted gene 14412, [Score=176, Expect=2e-46]; ENSMUSG00000094429, Gm19965, predicted gene, 19965, [Score=174, Expect=1e-44]; ENSMUSG00000092416, Zfp141, zinc finger protein 141, [Score=173, Expect=1e-44]} {Dmel: FBgn0032979, Clamp, Chromatin-linked adaptor for MSL proteins, [Score=151, Expect=4e-38]} {Celegans: WBGene00012639, fezf-1, FEZ Family zinc finger protein, [Score=123, Expect=2e-31]} {Smed: dd_Smed_v6_75162_0_1, dd_Smed_v6_75162_0_1, [Score=121, Expect=2e-31]} {RNA1509_38192, RNA1509_55873} {RNA1310_31280, RNA1509_55873} {RNA1509_55873, RNA815_10368}
47. MligTC455_44975 612 12.76 Mlig455_029692, Mlig455_034837

Neo: -

Age: -

1.685 - - - 0.951 0.734 -

Mlig455_029692 {REF} {Length: 2167} {TRANSSPLICED} {RNA1509_49332} {RNA1310_7362.1, RNA1509_49332} {RNA1509_49332, RNA815_14078}

Mlig455_034837 {REF} {Length: 2191} {TRANSSPLICED} {RNA1509_49332} {RNA1310_7362.1} {RNA815_14078}
48. MligTC455_04540 408 8.49 Mlig455_053630

Neo: Irradiation

Age: -

Region-specific R4: 3.892

Region-enriched R4: 2.125/0.00354

1.683 - 0.722 - 0.961 - - Mlig455_053630 {REF} {Length: 2503} {RNA1509_25806} {RNA1310_27297, RNA1509_25806} {RNA1509_25806, RNA815_14462}
49. MligTC455_13785 163 3.39 Mlig455_031328

Neo: -

Age: -

MAP3K19 1.681 - - - 0.961 0.720 - Mlig455_031328 {REF} {Length: 3663} {Pfam: Protein kinase domain [PF00069.27, score=168.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=145.5]; Ankyrin repeats (3 copies) [PF12796.9, score=108.7]; Ankyrin repeats (many copies) [PF13637.8, score=103.2]; Ankyrin repeat [PF13606.8, score=54.1]; Ankyrin repeats (many copies) [PF13857.8, score=51.4]; Ankyrin repeat [PF00023.32, score=47.3]; ABC1 atypical kinase-like domain [PF03109.18, score=30.1]; Fungal protein kinase [PF17667.3, score=24.1]; Kinase-like [PF14531.8, score=21.5]; Penicillin-Binding Protein C-terminus Family [PF06832.14, score=19.9]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=167, Expect=7e-42]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=158, Expect=1e-40]} {Dmel: FBgn0014006, Ask1, Apoptotic signal-regulating kinase 1, [Score=133, Expect=1e-31]} {Celegans: WBGene00016038, cst-2, Caenorhabditis STE20-like kinase, [Score=113, Expect=1e-26]} {Smed: dd_Smed_v6_10339_0_1, dd_Smed_v6_10339_0_1, [Score=136, Expect=7e-33]} {RNA1509_41875} {RNA1310_5347} {RNA815_6635.1}
50. MligTC455_45474 281 5.86 Mlig455_045349

Neo: Int S/G2/M

Age: -

1.68 - - - 0.964 0.716 - Mlig455_045349 {REF} {Length: 3749} {TRANSSPLICED} {Pfam: Ring finger domain [PF13639.8, score=37.4]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=24.6]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=23.3]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=21.5]} {Mouse: ENSMUSG00000038611, Phrf1, PHD and ring finger domains 1, [Score=50.1, Expect=2e-06]} {RNA1509_44163} {RNA1310_8209.1, RNA1509_44163} {RNA1509_44163, RNA815_13026.1}
51. MligTC455_31339 445 9.27 Mlig455_006071, Mlig455_053223

Neo: -

Age: -

NYNRIN, POLM 1.675 0.722 - - 0.953 - -

Mlig455_006071 {REF} {Length: 7416} {Pfam: DNA polymerase beta thumb [PF14791.8, score=75.5]; Integrase zinc binding domain [PF17921.3, score=59.0]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=54.0]; Integrase core domain [PF00665.28, score=45.1]; Fingers domain of DNA polymerase lambda [PF10391.11, score=24.2]; DNA polymerase beta palm [PF14792.8, score=20.8]} {Human: ENSG00000122678, POLM, DNA polymerase mu, [Score=214, Expect=3e-59]} {Mouse: ENSMUSG00000020474, Polm, polymerase (DNA directed), mu, [RH, Score=229, Expect=2e-64]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=127, Expect=2e-29]} {RNA1509_18343} {RNA1310_8091.1} {RNA815_3041}

Mlig455_053223 {REF} {Length: 2426} {Pfam: Integrase zinc binding domain [PF17921.3, score=61.1]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=55.1]; Integrase core domain [PF00665.28, score=46.3]; Integrase core domain [PF13683.8, score=18.4]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=90.9, Expect=6e-18]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=94.0, Expect=4e-19]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=118, Expect=4e-27]} {RNA1509_18367} {RNA1310_1117.1} {RNA815_895.1}
52. MligTC455_50895 674 14.05 Mlig455_008440, Mlig455_018231

Neo: Irradiation

Age: Up-Down-Down

1.674 0.706 - - 0.968 - -

Mlig455_008440 {REF} {Length: 3695} {TRANSSPLICED} {RNA1509_32831, RNA1509_53550, RNA1509_59445} {RNA1310_40800, RNA1509_32831, RNA1509_53550, RNA1509_59445} {RNA1509_32831, RNA1509_53550, RNA1509_59445, RNA815_25255}

Mlig455_018231 {REF} {Length: 4261} {TRANSSPLICED} {RNA1509_32831} {RNA1310_40800} {RNA815_25255}
53. MligTC455_26788 823 17.15 Mlig455_009191

Neo: Irradiation

Age: Up-Down-Down

Region-enriched R4: 1.115/0.02113

1.672 - - - 0.960 0.712 - Mlig455_009191 {REF} {Length: 11487} {TRANSSPLICED} {Dmel: FBgn0086690, Plp, Pericentrin-like protein, [Score=52.0, Expect=5e-06]} {RNA1509_5275} {RNA1310_379.1} {RNA815_407.1}
54. MligTC455_32970 882 18.38 Mlig455_036420

Neo: -

Age: logFC(26M/2M)=0.322

ESRRA 1.671 - - - 0.958 - 0.713 Mlig455_036420 {REF} {Length: 3551} {TRANSSPLICED} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=97.6]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=20.3]} {Human: ENSG00000173153, ESRRA, estrogen related receptor alpha, [RH, Score=156, Expect=1e-41]} {Mouse: ENSMUSG00000024955, Esrra, estrogen related receptor, alpha, [RH, Score=155, Expect=2e-41]} {Dmel: FBgn0035849, ERR, estrogen-related receptor, [RH, Score=150, Expect=2e-39]} {Celegans: WBGene00003630, nhr-40, Nuclear hormone receptor family member nhr-40, [RH, Score=120, Expect=2e-29]} {Smed: dd_Smed_v6_7551_0_1, dd_Smed_v6_7551_0_1, [Score=110, Expect=3e-25]} {RNA1509_13075, RNA1509_49940, RNA1509_7347} {RNA1310_9409, RNA1509_13075, RNA1509_49940, RNA1509_7347} {RNA1509_13075, RNA1509_49940, RNA1509_7347, RNA815_7739}
55. MligTC455_50037 209 4.34 Mlig455_004260

Neo: Germline

Age: -

Region-specific R4: 5.598

Region-enriched R4: 2.452/0.00729

1.659 - 0.702 - 0.957 - - Mlig455_004260 {REF} {Length: 1742} {Pfam: Innexin [PF00876.20, score=258.9]} {Dmel: FBgn0085387, shakB, shaking B, [Score=85.1, Expect=6e-18]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=173, Expect=1e-49]} {Smed: dd_Smed_v6_8019_0_1, dd_Smed_v6_8019_0_1, [Score=251, Expect=5e-79]} {RNA1509_11630} {RNA1310_21997} {RNA815_9078}
56. MligTC455_50228 1128 23.5 Mlig455_016788, Mlig455_016809

Neo: -

Age: -

RAB5B 1.658 - - - 0.952 0.706 -

Mlig455_016788 {REF} {Length: 1792} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=200.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=122.1]; ADP-ribosylation factor family [PF00025.23, score=50.5]; 50S ribosome-binding GTPase [PF01926.25, score=25.7]; Gtr1/RagA G protein conserved region [PF04670.14, score=22.8]; RsgA GTPase [PF03193.18, score=19.5]} {Human: ENSG00000111540, RAB5B, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=1e-96]; ENSG00000108774, RAB5C, RAB5C, member RAS oncogene family, [RH, Score=278, Expect=6e-95]; ENSG00000144566, RAB5A, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=4e-94]} {Mouse: ENSMUSG00000000711, Rab5b, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=7e-97]; ENSMUSG00000019173, Rab5c, RAB5C, member RAS oncogene family, [RH, Score=277, Expect=2e-95]; ENSMUSG00000017831, Rab5a, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=2e-94]} {Dmel: FBgn0014010, Rab5, [RH, Score=275, Expect=2e-94]} {Celegans: WBGene00004268, rab-5, RAB family, [RH, Score=275, Expect=8e-95]} {Smed: dd_Smed_v6_796_0_1, dd_Smed_v6_796_0_1, [RH, Score=278, Expect=2e-96]} {RNA1509_2296, RNA1509_42263} {RNA1310_25305, RNA1509_42263} {RNA1509_42263, RNA815_10567}

Mlig455_016809 {REF} {Length: 1784} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=200.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=122.1]; ADP-ribosylation factor family [PF00025.23, score=50.5]; 50S ribosome-binding GTPase [PF01926.25, score=25.7]; Gtr1/RagA G protein conserved region [PF04670.14, score=22.8]; RsgA GTPase [PF03193.18, score=19.5]} {Human: ENSG00000111540, RAB5B, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=1e-96]; ENSG00000108774, RAB5C, RAB5C, member RAS oncogene family, [RH, Score=278, Expect=6e-95]; ENSG00000144566, RAB5A, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=4e-94]} {Mouse: ENSMUSG00000000711, Rab5b, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=7e-97]; ENSMUSG00000019173, Rab5c, RAB5C, member RAS oncogene family, [RH, Score=277, Expect=2e-95]; ENSMUSG00000017831, Rab5a, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=2e-94]} {Dmel: FBgn0014010, Rab5, [RH, Score=275, Expect=2e-94]} {Celegans: WBGene00004268, rab-5, RAB family, [RH, Score=275, Expect=8e-95]} {Smed: dd_Smed_v6_796_0_1, dd_Smed_v6_796_0_1, [RH, Score=278, Expect=2e-96]} {RNA1509_2296} {RNA1310_25305, RNA1509_2296} {RNA1509_2296, RNA815_10567}
57. MligTC455_09142 706 14.71 Mlig455_029007

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.314

1.652 - - 0.702 0.950 - - Mlig455_029007 {REF} {Length: 806} {RNA1310_55515} {RNA815_30023}
58. MligTC455_26510 185 3.85 Mlig455_043061

Neo: Germline

Age: Up-Down-Down

Region-specific R4: 5.246

ABCA8 1.652 - 0.700 - 0.952 - - Mlig455_043061 {REF} {Length: 5479} {Pfam: ABC transporter [PF00005.29, score=117.5]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=51.6]; ABC-2 family transporter protein [PF12698.9, score=28.9]; AAA domain [PF13476.8, score=24.1]; RecF/RecN/SMC N terminal domain [PF02463.21, score=20.9]; P-loop containing region of AAA domain [PF13555.8, score=20.4]} {Human: ENSG00000141338, ABCA8, ATP binding cassette subfamily A member 8, [Score=206, Expect=1e-52]} {Mouse: ENSMUSG00000041828, Abca8a, ATP-binding cassette, sub-family A (ABC1), member 8a, [Score=195, Expect=1e-49]} {Dmel: FBgn0031170, CG1718, [Score=155, Expect=2e-37]} {Celegans: WBGene00000020, abt-2, ABC Transporter family, [Score=127, Expect=8e-29]} {Smed: dd_Smed_v6_2300_0_5, dd_Smed_v6_2300_0_5, [Score=152, Expect=8e-37]} {RNA1509_15115, RNA1509_15846} {RNA1310_1051.1, RNA1509_15115, RNA1509_15846} {RNA1509_15115, RNA1509_15846, RNA815_2076}
59. MligTC455_18817 467 9.73 Mlig455_044086

Neo: -

Age: -

Region-enriched R5: 1.818/0.01168

SPHK1 0.993 - - - 0.993 - - Mlig455_044086 {REF} {Length: 3239} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=81.2]; YegS C-terminal NAD kinase beta sandwich-like domain [PF19279.1, score=30.1]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [RH, Score=196, Expect=9e-58]} {Mouse: ENSMUSG00000061878, Sphk1, sphingosine kinase 1, [RH, Score=196, Expect=4e-58]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [RH, Score=150, Expect=4e-39]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [Score=127, Expect=3e-32]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [Score=146, Expect=3e-39]} {RNA1509_40292, RNA1509_50975} {RNA1310_16793, RNA1509_40292} {RNA1509_40292, RNA815_6929}
60. MligTC455_22967 511 10.65 Mlig455_025359

Neo: -

Age: Up-Down-Down

Region-enriched R4: 1.418/0.03872

NCK2 0.988 - - - 0.988 - - Mlig455_025359 {REF} {Length: 4945} {TRANSSPLICED} {Pfam: SH3 domain [PF00018.30, score=149.7]; Variant SH3 domain [PF14604.8, score=137.1]; Variant SH3 domain [PF07653.19, score=83.1]; SH2 domain [PF00017.26, score=58.0]; Bacterial SH3 domain [PF08239.13, score=33.5]; SH3 domain [PF17902.3, score=28.6]; Bacterial dipeptidyl-peptidase Sh3 domain [PF18348.3, score=18.3]} {Human: ENSG00000071051, NCK2, NCK adaptor protein 2, [Score=226, Expect=1e-68]} {Mouse: ENSMUSG00000032475, Nck1, non-catalytic region of tyrosine kinase adaptor protein 1, [Score=163, Expect=2e-45]} {Dmel: FBgn0010583, dock, dreadlocks, [Score=129, Expect=2e-32]} {Celegans: WBGene00006410, nck-1, NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family, [Score=219, Expect=5e-66]} {Smed: dd_Smed_v6_4816_0_2, dd_Smed_v6_4816_0_2, [Score=215, Expect=2e-62]} {RNA1509_17077, RNA1509_34254, RNA1509_52928} {RNA1310_9858, RNA1509_17077, RNA1509_34254, RNA1509_52928} {RNA1509_17077, RNA1509_34254, RNA1509_52928, RNA815_11879}
61. MligTC455_32876 668 13.92 Mlig455_039686

Neo: -

Age: Down-Down-Up

RAC1 0.988 - - - 0.988 - - Mlig455_039686 {REF} {Length: 3690} {Pfam: Ras family [PF00071.24, score=163.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=71.2]; ADP-ribosylation factor family [PF00025.23, score=30.5]} {Human: ENSG00000136238, RAC1, Rac family small GTPase 1, [Score=225, Expect=1e-74]; ENSG00000169750, RAC3, Rac family small GTPase 3, [Score=219, Expect=1e-72]; ENSG00000128340, RAC2, Rac family small GTPase 2, [Score=216, Expect=2e-71]} {Mouse: ENSMUSG00000001847, Rac1, Rac family small GTPase 1, [Score=225, Expect=7e-75]; ENSMUSG00000018012, Rac3, Rac family small GTPase 3, [Score=219, Expect=9e-73]; ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [Score=214, Expect=7e-71]} {Dmel: FBgn0010333, Rac1, [Score=224, Expect=2e-74]} {Celegans: WBGene00003239, mig-2, Rac-like GTPase, [Score=221, Expect=2e-73]} {Smed: dd_Smed_v6_698_0_1, dd_Smed_v6_698_0_1, [Score=210, Expect=2e-69]} {RNA1509_28989} {RNA1310_27953} {RNA815_13447}
62. MligTC455_33785 1166 24.28 Mlig455_046906

Neo: -

Age: -

LETM1 0.987 - - - 0.987 - - Mlig455_046906 {REF} {Length: 4438} {Pfam: LETM1-like protein [PF07766.15, score=292.9]} {Human: ENSG00000168924, LETM1, leucine zipper and EF-hand containing transmembrane protein 1, [RH, Score=333, Expect=2e-101]} {Mouse: ENSMUSG00000005299, Letm1, leucine zipper-EF-hand containing transmembrane protein 1, [RH, Score=331, Expect=7e-101]} {Dmel: FBgn0284252, Letm1, Leucine zipper and EF-hand containing transmembrane protein 1, [RH, Score=310, Expect=7e-91]} {Celegans: WBGene00010279, letm-1, LETM1 (Leucine zipper, EF-hand, TransMembrane mitochondrial protein) homolog, [RH, Score=330, Expect=2e-100]} {Smed: dd_Smed_v6_4348_0_1, dd_Smed_v6_4348_0_1, [RH, Score=378, Expect=4e-119]} {RNA1509_19480, RNA1509_28848, RNA1509_3368, RNA1509_52640} {RNA1310_3687.1, RNA1509_19480, RNA1509_28848, RNA1509_52640} {RNA1509_19480, RNA1509_28848, RNA1509_52640, RNA815_1948}
63. MligTC455_26487 338 7.05 Mlig455_063885

Neo: -

Age: -

Region-enriched R5: 2.302/0.02522

CCDC88C 0.986 - - - 0.986 - - Mlig455_063885 {REF} {Length: 5084} {TRANSSPLICED} {Human: ENSG00000015133, CCDC88C, coiled-coil domain containing 88C, [Score=102, Expect=3e-21]; ENSG00000115355, CCDC88A, coiled-coil domain containing 88A, [Score=100, Expect=1e-20]} {Mouse: ENSMUSG00000032740, Ccdc88a, coiled coil domain containing 88A, [Score=94.4, Expect=8e-19]; ENSMUSG00000021182, Ccdc88c, coiled-coil domain containing 88C, [Score=94.0, Expect=1e-18]} {Dmel: FBgn0283724, Girdin, [Score=91.3, Expect=5e-18]} {Celegans: WBGene00013082, grdn-1, Girdin homolog, [Score=55.8, Expect=2e-07]} {Smed: dd_Smed_v6_5291_0_2, dd_Smed_v6_5291_0_2, [Score=144, Expect=1e-34]} {RNA1509_18704} {RNA1310_2232.1, RNA1509_18704} {RNA1509_18704, RNA815_6605}
64. MligTC455_17189 979 20.39 Mlig455_060262

Neo: -

Age: Down-Down-Up

MCRS1 0.985 - - - 0.985 - - Mlig455_060262 {REF} {Length: 2447} {TRANSSPLICED} {Pfam: N-terminal region of micro-spherule protein [PF13325.8, score=88.1]} {Human: ENSG00000187778, MCRS1, microspherule protein 1, [Score=90.5, Expect=3e-19]} {Mouse: ENSMUSG00000037570, Mcrs1, microspherule protein 1, [Score=93.2, Expect=2e-20]} {Dmel: FBgn0263832, Rcd5, Reduction in Cnn dots 5, [Score=80.1, Expect=4e-16]} {Celegans: WBGene00018026, F35A5.4, [Score=48.9, Expect=4e-06]} {Smed: dd_Smed_v6_4102_0_1, dd_Smed_v6_4102_0_1, [Score=77.8, Expect=1e-15]} {RNA1509_8483} {RNA1310_19335} {RNA815_6260}
65. MligTC455_33954 280 5.84 Mlig455_058149

Neo: -

Age: -

0.984 - - - 0.984 - - Mlig455_058149 {REF} {Length: 3221} {RNA1310_32323} {RNA815_59403}
66. MligTC455_23519 291 6.06 Mlig455_043085

Neo: -

Age: logFC(26M/2M)=0.337

Region-enriched R5: 1.705/0.02838

DOLPP1 0.983 - - - 0.983 - - Mlig455_043085 {REF} {Length: 1650} {Pfam: PAP2 superfamily [PF01569.23, score=51.2]} {Human: ENSG00000167130, DOLPP1, dolichyldiphosphatase 1, [Score=117, Expect=6e-33]} {Mouse: ENSMUSG00000026856, Dolpp1, dolichyl pyrophosphate phosphatase 1, [RH, Score=113, Expect=1e-32]} {Smed: dd_Smed_v6_6607_0_1, dd_Smed_v6_6607_0_1, [Score=119, Expect=2e-34]} {RNA1509_22706} {RNA1310_2620} {RNA815_4895}
67. MligTC455_41814 525 10.93 Mlig455_067134

Neo: Irradiation

Age: -

PPP1R2 0.983 - - - 0.983 - - Mlig455_067134 {REF} {Length: 2837} {TRANSSPLICED} {Pfam: Protein phosphatase inhibitor 2 (IPP-2) [PF04979.16, score=107.7]} {Human: ENSG00000184203, PPP1R2, protein phosphatase 1 regulatory inhibitor subunit 2, [RH, Score=101, Expect=3e-26]} {Mouse: ENSMUSG00000047714, Ppp1r2, protein phosphatase 1, regulatory inhibitor subunit 2, [RH, Score=91.3, Expect=1e-22]} {Dmel: FBgn0028429, I-2, Inhibitor-2, [RH, Score=73.6, Expect=4e-16]} {Celegans: WBGene00021312, szy-2, Suppressor of ZYg-1, [RH, Score=92.8, Expect=2e-23]} {Smed: dd_Smed_v6_5135_0_1, dd_Smed_v6_5135_0_1, [RH, Score=72.4, Expect=4e-16]} {RNA1509_24723, RNA1509_51446, RNA1509_56353} {RNA1310_40287, RNA1509_24723, RNA1509_51446, RNA1509_56353} {RNA1509_24723, RNA1509_51446, RNA1509_56353, RNA815_26897}
68. MligTC455_07773 773 16.11 Mlig455_031541

Neo: -

Age: -

0.982 - - - 0.982 - - Mlig455_031541 {REF} {Length: 1316} {NoTransDecoderORF} {RNA1509_50184} {RNA1310_22266} {RNA815_9720}
69. MligTC455_43288 538 11.2 Mlig455_045261

Neo: -

Age: -

Region-enriched R5: 1.017/0.02271

LMBRD2 0.982 - - - 0.982 - - Mlig455_045261 {REF} {Length: 2770} {TRANSSPLICED} {Pfam: LMBR1-like membrane protein [PF04791.18, score=445.5]} {Human: ENSG00000164187, LMBRD2, LMBR1 domain containing 2, [RH, Score=455, Expect=1e-150]} {Mouse: ENSMUSG00000039704, Lmbrd2, LMBR1 domain containing 2, [RH, Score=449, Expect=1e-148]; ENSMUSG00000116236, Lmbrd2, LMBR1 domain containing 2, [RH, Score=449, Expect=1e-148]} {Dmel: FBgn0037689, CG8135, [RH, Score=429, Expect=5e-141]} {Celegans: WBGene00008165, C47G2.4, LMBR1 domain-containing protein 2 homolog, [RH, Score=335, Expect=2e-105]} {Smed: dd_Smed_v6_8597_0_1, dd_Smed_v6_8597_0_1, [RH, Score=444, Expect=6e-147]} {RNA1509_11891, RNA1509_44667} {RNA1310_7078.1, RNA1509_11891, RNA1509_44667} {RNA1509_11891, RNA1509_44667, RNA815_12918}
70. MligTC455_50072 536 11.17 Mlig455_043235, Mlig455_043241

Neo: -

Age: -

0.982 - - - 0.982 - -

Mlig455_043235 {REF} {Length: 2717} {RNA1509_46424} {RNA1310_8905} {RNA815_3382.1}

Mlig455_043241 {REF} {Length: 2387} {RNA1509_46424} {RNA1310_12565} {RNA815_3382.1}
71. MligTC455_50225 779 16.23 Mlig455_057107

Neo: Irradiation

Age: Up-Down-Down

0.982 - - - 0.982 - - Mlig455_057107 {REF} {Length: 5818} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=23.5]} {RNA1509_16300, RNA1509_22780, RNA1509_34391, RNA1509_43361, RNA1509_8991} {RNA1310_9850.1, RNA1509_16300, RNA1509_22780, RNA1509_34391, RNA1509_43361, RNA1509_8991} {RNA1509_16300, RNA1509_22780, RNA1509_34391, RNA1509_43361, RNA1509_8991, RNA815_3349}
72. MligTC455_20772 671 13.98 Mlig455_007828

Neo: -

Age: -

0.981 - - - 0.981 - - Mlig455_007828 {REF} {Length: 2327} {TRANSSPLICED} {Pfam: Ezrin/radixin/moesin family [PF00769.21, score=25.0]} {RNA1509_16297, RNA1509_54141} {RNA1310_16574.1, RNA1509_16297, RNA1509_54141} {RNA1509_16297, RNA1509_54141, RNA815_19017}
73. MligTC455_23242 633 13.19 Mlig455_001209

Neo: -

Age: -

Region-enriched R5: 1.808/0.00013

SLC7A14 0.981 - - - 0.981 - - Mlig455_001209 {REF} {Length: 3590} {Pfam: Amino acid permease [PF13520.8, score=127.0]; Amino acid permease [PF00324.23, score=113.5]; C-terminus of AA_permease [PF13906.8, score=74.4]} {Human: ENSG00000013293, SLC7A14, solute carrier family 7 member 14, [RH, Score=480, Expect=1e-157]} {Mouse: ENSMUSG00000069072, Slc7a14, solute carrier family 7 (cationic amino acid transporter, y+ system), member 14, [RH, Score=471, Expect=4e-154]} {Dmel: FBgn0036764, CG5535, [Score=379, Expect=4e-121]} {Celegans: WBGene00016806, C50D2.2, [Score=338, Expect=5e-106]} {Smed: dd_Smed_v6_16390_0_1, dd_Smed_v6_16390_0_1, [Score=332, Expect=3e-106]} {RNA1509_29954} {RNA1310_7437} {RNA815_3407}
74. MligTC455_37959 177 3.69 Mlig455_038764

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.399

SCNN1B 0.981 - - - 0.981 - - Mlig455_038764 {REF} {Length: 3158} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=192.0]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=49.7, Expect=1e-05]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=68.9, Expect=7e-12]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=57.4, Expect=2e-08]} {Smed: dd_Smed_v6_26855_0_1, dd_Smed_v6_26855_0_1, [Score=168, Expect=4e-45]} {RNA1509_35658, RNA1509_58401} {RNA1310_10317.1, RNA1509_35658, RNA1509_58401} {RNA1509_35658, RNA1509_58401, RNA815_3305}
75. MligTC455_47289 1718 35.8 Mlig455_028690, Mlig455_028713

Neo: Neoblast

Age: logFC(26M/2M)=0.203

SRSF1 0.981 - - - 0.981 - -

Mlig455_028690 {REF} {Length: 2107} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=64.6]} {Human: ENSG00000136450, SRSF1, serine and arginine rich splicing factor 1, [Score=121, Expect=3e-33]} {Mouse: ENSMUSG00000098301, Srsf1, serine/arginine-rich splicing factor 1, [Score=121, Expect=2e-33]; ENSMUSG00000018379, Srsf1, serine/arginine-rich splicing factor 1, [Score=121, Expect=2e-33]} {Dmel: FBgn0283477, SF2, Splicing factor 2, [Score=128, Expect=4e-36]} {Celegans: WBGene00004700, rsp-3, Probable splicing factor, arginine/serine-rich 3, [Score=114, Expect=9e-31]} {Smed: dd_Smed_v6_3866_0_10, dd_Smed_v6_3866_0_10, [Score=130, Expect=1e-37]} {RNA1509_15981} {RNA1310_13088.1} {RNA815_4976.1}

Mlig455_028713 {REF} {Length: 2334} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=105.6]; RNA binding motif [PF08777.13, score=24.5]; Nup53/35/40-type RNA recognition motif [PF14605.8, score=19.8]} {Human: ENSG00000136450, SRSF1, serine and arginine rich splicing factor 1, [RH, Score=206, Expect=6e-66]} {Mouse: ENSMUSG00000018379, Srsf1, serine/arginine-rich splicing factor 1, [RH, Score=206, Expect=4e-66]; ENSMUSG00000098301, Srsf1, serine/arginine-rich splicing factor 1, [RH, Score=206, Expect=4e-66]} {Dmel: FBgn0283477, SF2, Splicing factor 2, [RH, Score=213, Expect=7e-69]} {Celegans: WBGene00004700, rsp-3, Probable splicing factor, arginine/serine-rich 3, [RH, Score=180, Expect=4e-56]} {Smed: dd_Smed_v6_3866_0_10, dd_Smed_v6_3866_0_10, [RH, Score=223, Expect=2e-73]} {RNA1509_15981, RNA1509_25451, RNA1509_29334, RNA1509_42978} {RNA1310_13088.1, RNA1509_25451, RNA1509_29334, RNA1509_42978} {RNA1509_25451, RNA1509_29334, RNA1509_42978, RNA815_4976.1}
76. MligTC455_52703 503 10.48 Mlig455_067967

Neo: -

Age: Up-Down-Up

DSCAM 0.981 - - - 0.981 - - Mlig455_067967 {REF} {Length: 7940} {Pfam: Fibronectin type III domain [PF00041.23, score=181.2]; Immunoglobulin domain [PF13927.8, score=132.1]; Immunoglobulin I-set domain [PF07679.18, score=91.0]; Immunoglobulin domain [PF13895.8, score=77.5]; Immunoglobulin domain [PF00047.27, score=62.1]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=49.3]; Immunoglobulin V-set domain [PF07686.19, score=46.5]} {Human: ENSG00000171587, DSCAM, DS cell adhesion molecule, [RH, Score=242, Expect=2e-63]; ENSG00000177103, DSCAML1, DS cell adhesion molecule like 1, [RH, Score=239, Expect=3e-62]} {Mouse: ENSMUSG00000050272, Dscam, DS cell adhesion molecule, [RH, Score=238, Expect=3e-62]; ENSMUSG00000032087, Dscaml1, DS cell adhesion molecule like 1, [RH, Score=238, Expect=2e-62]} {Dmel: FBgn0263219, Dscam4, Down syndrome cell adhesion molecule 4, [Score=221, Expect=4e-57]} {Celegans: WBGene00004215, ptp-3, Tyrosine-protein phosphatase Lar-like, [Score=79.7, Expect=2e-14]} {Smed: dd_Smed_v6_3024_0_1, dd_Smed_v6_3024_0_1, [RH, Score=330, Expect=1e-90]} {RNA1509_2497} {RNA1310_1699.1} {RNA815_16029}
77. MligTC455_21585 922 19.22 Mlig455_006776

Neo: -

Age: Up-Down-Down

PAFAH1B1 0.98 - - - 0.980 - - Mlig455_006776 {REF} {Length: 4438} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=214.0]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=61.9]; Nucleoporin Nup120/160 [PF11715.10, score=26.6]; LisH [PF08513.13, score=25.6]; WD40 region of Ge1, enhancer of mRNA-decapping protein [PF16529.7, score=23.8]; Nup133 N terminal like [PF08801.13, score=21.7]} {Human: ENSG00000007168, PAFAH1B1, platelet activating factor acetylhydrolase 1b regulatory subunit 1, [RH, Score=592, Expect=0.0]} {Mouse: ENSMUSG00000020745, Pafah1b1, platelet-activating factor acetylhydrolase, isoform 1b, subunit 1, [RH, Score=592, Expect=0.0]} {Dmel: FBgn0015754, Lis-1, Lissencephaly-1, [RH, Score=560, Expect=0.0]} {Celegans: WBGene00003047, lis-1, Lissencephaly-1 homolog, [RH, Score=481, Expect=1e-169]} {Smed: dd_Smed_v6_3359_0_1, dd_Smed_v6_3359_0_1, [RH, Score=528, Expect=0.0]} {RNA1509_19057, RNA1509_26707} {RNA1310_18546, RNA1509_19057, RNA1509_26707} {RNA1509_19057, RNA1509_26707, RNA815_9438}
78. MligTC455_34286 641 13.35 Mlig455_057009

Neo: -

Age: -

0.98 - - - 0.980 - - Mlig455_057009 {REF} {Length: 1242} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_35262} {RNA1310_20897, RNA1509_35262} {RNA1509_35262, RNA815_22915.1}
79. MligTC455_41300 1166 24.29 Mlig455_028175, Mlig455_028246

Neo: -

Age: Up-Down-Down

0.98 - - - 0.980 - -

Mlig455_028175 {REF} {Length: 1858} {RNA1509_29769, RNA1509_38014, RNA1509_45692, RNA1509_55801} {RNA1310_15559, RNA1509_29769, RNA1509_38014, RNA1509_45692} {RNA1509_29769, RNA1509_38014, RNA1509_45692, RNA815_13376}

Mlig455_028246 {REF} {Length: 1854} {RNA1509_55801} {RNA1310_15559, RNA1509_55801} {RNA1509_55801, RNA815_13376}
80. MligTC455_46914 423 8.82 Mlig455_060252

Neo: Irradiation

Age: -

NOTCH3 0.98 - - - 0.980 - - Mlig455_060252 {REF} {Length: 3099} {Pfam: EGF-like domain [PF00008.29, score=49.3]; Calcium-binding EGF domain [PF07645.17, score=39.7]; Human growth factor-like EGF [PF12661.9, score=29.8]; EGF domain [PF12947.9, score=25.8]; EGF-like domain [PF07974.15, score=23.7]} {Human: ENSG00000074181, NOTCH3, notch 3, [Score=86.3, Expect=7e-17]} {Mouse: ENSMUSG00000038146, Notch3, notch 3, [Score=82.4, Expect=7e-16]} {Dmel: FBgn0051665, wry, weary, [Score=95.5, Expect=3e-20]} {Celegans: WBGene00001609, glp-1, [Score=74.7, Expect=9e-14]} {Smed: dd_Smed_v6_6929_0_1, dd_Smed_v6_6929_0_1, [Score=115, Expect=1e-27]} {RNA1509_21381} {RNA1310_11756, RNA1509_21381} {RNA1509_21381, RNA815_17372.1}
81. MligTC455_50668 1116 23.26 Mlig455_053388

Neo: Int S/G2/M

Age: Up-Down-Down

Region-enriched R4: 1.010/0.04692

APPL1 0.98 - - - 0.980 - - Mlig455_053388 {REF} {Length: 3309} {Pfam: BAR domain of APPL family [PF16746.7, score=121.5]} {Human: ENSG00000157500, APPL1, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1, [Score=189, Expect=7e-51]} {Mouse: ENSMUSG00000040760, Appl1, adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1, [Score=189, Expect=3e-51]} {RNA1509_9001} {RNA1310_5359, RNA1509_9001} {RNA1509_9001, RNA815_4473.1}
82. MligTC455_26232 237 4.94 Mlig455_044561

Neo: Irradiation

Age: Down-Up-Down

PHF8 0.979 - - - 0.979 - - Mlig455_044561 {REF} {Length: 3787} {TRANSSPLICED} {Pfam: Jumonji helical domain [PF17811.3, score=64.9]; JmjC domain, hydroxylase [PF02373.24, score=26.0]; Cupin-like domain [PF13621.8, score=25.6]} {Human: ENSG00000172943, PHF8, PHD finger protein 8, [RH, Score=291, Expect=2e-86]; ENSG00000006459, KDM7A, lysine demethylase 7A, [RH, Score=289, Expect=3e-86]} {Mouse: ENSMUSG00000041229, Phf8, PHD finger protein 8, [RH, Score=291, Expect=2e-86]; ENSMUSG00000042599, Kdm7a, lysine (K)-specific demethylase 7A, [RH, Score=287, Expect=9e-86]} {Dmel: FBgn0037659, Kdm2, Lysine (K)-specific demethylase 2, [Score=234, Expect=8e-66]} {Celegans: WBGene00017920, jmjd-1.2, Lysine-specific demethylase 7 homolog, [RH, Score=238, Expect=4e-68]} {Smed: dd_Smed_v6_10417_0_1, dd_Smed_v6_10417_0_1, [RH, Score=282, Expect=4e-89]} {RNA1509_14419} {RNA1310_7326, RNA1509_14419} {RNA1509_14419, RNA815_2278.1}
83. MligTC455_43274 2146 44.71 Mlig455_021861, Mlig455_021937

Neo: -

Age: -

0.978 - - - 0.978 - -

Mlig455_021861 {REF} {Length: 3255} {TRANSSPLICED} {Pfam: PAS fold [PF08447.14, score=26.4]; PAS domain [PF14598.8, score=25.5]} {RNA1509_28562, RNA1509_32390} {RNA1310_24520.1, RNA1509_28562} {RNA1509_28562, RNA815_15256}

Mlig455_021937 {REF} {Length: 3201} {Pfam: PAS domain [PF14598.8, score=25.9]} {RNA1509_32390} {RNA1310_24520.1, RNA1509_32390} {RNA1509_32390, RNA815_15256}
84. MligTC455_50884 2332 48.58 Mlig455_058834

Neo: Neoblast, stringent

Age: logFC(26M/2M)=-0.163

HDAC2 0.978 - - - 0.978 - - Mlig455_058834 {REF} {Length: 2353} {TRANSSPLICED} {Pfam: Histone deacetylase domain [PF00850.21, score=294.3]} {Human: ENSG00000196591, HDAC2, histone deacetylase 2, [RH, Score=753, Expect=0.0]; ENSG00000116478, HDAC1, histone deacetylase 1, [RH, Score=741, Expect=0.0]} {Mouse: ENSMUSG00000019777, Hdac2, histone deacetylase 2, [RH, Score=752, Expect=0.0]; ENSMUSG00000028800, Hdac1, histone deacetylase 1, [RH, Score=742, Expect=0.0]} {Dmel: FBgn0015805, HDAC1, Histone deacetylase 1, [RH, Score=749, Expect=0.0]} {Celegans: WBGene00001834, hda-1, Histone deacetylase 1, [RH, Score=625, Expect=0.0]} {Smed: dd_Smed_v6_695_0_1, dd_Smed_v6_695_0_1, [RH, Score=727, Expect=0.0]} {RNA1509_37679} {RNA1310_14875.1} {RNA815_6702}
85. MligTC455_17506 450 9.38 Mlig455_015262

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.648

Region-enriched R4: 1.874/0.03652

0.977 - - - 0.977 - - Mlig455_015262 {REF} {Length: 2975} {TRANSSPLICED} {RNA1509_4515} {RNA1310_5427} {RNA815_2140.1}
86. MligTC455_19164 643 13.39 Mlig455_066812

Neo: -

Age: -

TBL2 0.977 - - - 0.977 - - Mlig455_066812 {REF} {Length: 2791} {Pfam: WD domain, G-beta repeat [PF00400.34, score=72.6]} {Human: ENSG00000106638, TBL2, transducin beta like 2, [RH, Score=296, Expect=4e-96]} {Mouse: ENSMUSG00000005374, Tbl2, transducin (beta)-like 2, [RH, Score=283, Expect=2e-90]} {Dmel: FBgn0032030, Wdr82, WD repeat domain 82, [Score=51.2, Expect=9e-07]} {Celegans: WBGene00009784, F46C5.9, [RH, Score=174, Expect=5e-49]} {Smed: dd_Smed_v6_4372_0_1, dd_Smed_v6_4372_0_1, [RH, Score=249, Expect=1e-77]} {RNA1509_12484, RNA1509_27098, RNA1509_8303} {RNA1310_11971, RNA1509_12484, RNA1509_27098, RNA1509_8303} {RNA1509_12484, RNA1509_27098, RNA1509_8303, RNA815_4594}
87. MligTC455_36102 672 13.99 Mlig455_043535

Neo: -

Age: -

CUX1 0.977 - - - 0.977 - - Mlig455_043535 {REF} {Length: 4531} {Pfam: CUT domain [PF02376.17, score=229.5]; Homeodomain [PF00046.31, score=53.4]; Homeobox KN domain [PF05920.13, score=27.9]} {Human: ENSG00000257923, CUX1, cut like homeobox 1, [Score=191, Expect=6e-49]; ENSG00000111249, CUX2, cut like homeobox 2, [Score=187, Expect=1e-47]} {Mouse: ENSMUSG00000042589, Cux2, cut-like homeobox 2, [RH, Score=192, Expect=2e-49]} {Dmel: FBgn0004198, ct, cut, [RH, Score=145, Expect=1e-34]} {Celegans: WBGene00000464, ceh-44, Homeobox protein cut-like ceh-44, [RH, Score=147, Expect=1e-35]} {Smed: dd_Smed_v6_13843_0_1, dd_Smed_v6_13843_0_1, [RH, Score=131, Expect=7e-31]} {RNA1509_6534} {RNA1310_2215.2} {RNA815_1260}
88. MligTC455_46747 352 7.32 Mlig455_040380

Neo: -

Age: Up-Down-Up

ANKRD11 0.977 - - - 0.977 - - Mlig455_040380 {REF} {Length: 5078} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=63.8]; Ankyrin repeats (many copies) [PF13637.8, score=63.7]; Ankyrin repeats (many copies) [PF13857.8, score=62.2]; Ankyrin repeat [PF00023.32, score=53.6]; Ankyrin repeat [PF13606.8, score=43.7]} {Human: ENSG00000167522, ANKRD11, ankyrin repeat domain 11, [RH, Score=134, Expect=1e-30]; ENSG00000101745, ANKRD12, ankyrin repeat domain 12, [RH, Score=128, Expect=5e-29]} {Mouse: ENSMUSG00000035569, Ankrd11, ankyrin repeat domain 11, [RH, Score=134, Expect=4e-31]; ENSMUSG00000034647, Ankrd12, ankyrin repeat domain 12, [RH, Score=129, Expect=2e-29]} {Dmel: FBgn0036305, CG10984, [Score=104, Expect=1e-22]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=91.3, Expect=5e-18]} {Smed: dd_Smed_v6_9297_0_1, dd_Smed_v6_9297_0_1, [Score=152, Expect=2e-37]} {RNA1509_17750} {RNA1310_3406} {RNA815_33283}
89. MligTC455_48952 192 3.99 Mlig455_025241

Neo: -

Age: -

0.977 - - - 0.977 - - Mlig455_025241 {REF} {Length: 1573} {RNA1509_50956} {RNA1310_66253.1} {RNA815_9458.1}
90. MligTC455_19324 1062 22.13 Mlig455_045112

Neo: Int S/G2/M

Age: -

KCTD21 0.976 - - - 0.976 - - Mlig455_045112 {REF} {Length: 1839} {TRANSSPLICED} {Pfam: BTB/POZ domain [PF02214.24, score=57.7]; N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) [PF07221.13, score=18.0]} {Human: ENSG00000188997, KCTD21, potassium channel tetramerization domain containing 21, [RH, Score=102, Expect=7e-27]} {Mouse: ENSMUSG00000044952, Kctd21, potassium channel tetramerisation domain containing 21, [RH, Score=103, Expect=4e-26]} {Dmel: FBgn0038839, Ktl, Kctd12-like, [Score=86.7, Expect=4e-20]} {Celegans: WBGene00014848, VM106R.1, [Score=82.4, Expect=4e-18]} {Smed: dd_Smed_v6_8654_0_1, dd_Smed_v6_8654_0_1, [RH, Score=192, Expect=5e-61]} {RNA1509_8015} {RNA1310_35464.2} {RNA815_25284}
91. MligTC455_29193 967 20.15 Mlig455_018315, Mlig455_061014, Mlig455_067207

Neo: -

Age: Down-Down-Up

0.976 - - - 0.976 - -

Mlig455_018315 {REF} {Length: 2676} {TRANSSPLICED} {RNA1509_52931} {RNA1310_28021} {RNA815_28552}

Mlig455_061014 {REF} {Length: 2001} {RNA1310_29654.1} {RNA815_17301.1}

Mlig455_067207 {REF} {Length: 584} {TRANSSPLICED} {RNA1310_29654.1} {RNA815_17301.1}
92. MligTC455_23551 537 11.19 Mlig455_007655

Neo: -

Age: -

CSNK1G1 0.975 - - - 0.975 - - Mlig455_007655 {REF} {Length: 4258} {Pfam: Protein kinase domain [PF00069.27, score=100.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=55.0]; Fungal protein kinase [PF17667.3, score=29.3]} {Human: ENSG00000169118, CSNK1G1, casein kinase 1 gamma 1, [RH, Score=527, Expect=0.0]; ENSG00000151292, CSNK1G3, casein kinase 1 gamma 3, [RH, Score=521, Expect=0.0]} {Mouse: ENSMUSG00000032384, Csnk1g1, casein kinase 1, gamma 1, [RH, Score=535, Expect=0.0]; ENSMUSG00000073563, Csnk1g3, casein kinase 1, gamma 3, [RH, Score=518, Expect=0.0]} {Dmel: FBgn0250823, gish, gilgamesh, [RH, Score=508, Expect=4e-178]} {Celegans: WBGene00013709, csnk-1, Casein kinase I gamma, [RH, Score=512, Expect=0.0]} {Smed: dd_Smed_v6_8508_0_2, dd_Smed_v6_8508_0_2, [RH, Score=462, Expect=2e-161]} {RNA1509_16024, RNA1509_20026} {RNA1310_20582.1, RNA1509_16024} {RNA1509_16024, RNA815_13120.1}
93. MligTC455_23552 539 11.23 Mlig455_020886

Neo: Irradiation

Age: -

CSNK1G1 0.975 - - - 0.975 - - Mlig455_020886 {REF} {Length: 4055} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=100.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=55.0]; Fungal protein kinase [PF17667.3, score=29.4]} {Human: ENSG00000169118, CSNK1G1, casein kinase 1 gamma 1, [RH, Score=527, Expect=0.0]; ENSG00000151292, CSNK1G3, casein kinase 1 gamma 3, [RH, Score=524, Expect=0.0]} {Mouse: ENSMUSG00000032384, Csnk1g1, casein kinase 1, gamma 1, [RH, Score=535, Expect=0.0]; ENSMUSG00000073563, Csnk1g3, casein kinase 1, gamma 3, [RH, Score=520, Expect=0.0]} {Dmel: FBgn0250823, gish, gilgamesh, [RH, Score=515, Expect=0.0]} {Celegans: WBGene00013709, csnk-1, Casein kinase I gamma, [RH, Score=513, Expect=0.0]} {Smed: dd_Smed_v6_8508_0_2, dd_Smed_v6_8508_0_2, [RH, Score=462, Expect=1e-161]} {RNA1509_20026, RNA1509_31077} {RNA1310_19544.3, RNA1509_31077} {RNA1509_31077, RNA815_13120.1}
94. MligTC455_29376 74 1.54 Mlig455_005795

Neo: -

Age: Down-Down-Down

0.975 - - - 0.975 - - Mlig455_005795 {REF} {Length: 8723} {RNA1509_34218} {RNA1310_18727} {RNA815_16176.1}
95. MligTC455_32497 774 16.13 Mlig455_070904

Neo: -

Age: -

SNF8 0.975 - - - 0.975 - - Mlig455_070904 {REF} {Length: 2221} {TRANSSPLICED} {Pfam: EAP30/Vps36 family [PF04157.18, score=212.8]; CDK5 regulatory subunit-associated protein 3 [PF05600.14, score=20.2]} {Human: ENSG00000159210, SNF8, SNF8, ESCRT-II complex subunit, [RH, Score=244, Expect=5e-81]} {Mouse: ENSMUSG00000006058, Snf8, SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae), [RH, Score=247, Expect=4e-82]} {Dmel: FBgn0260940, lsn, larsen, [RH, Score=222, Expect=2e-72]} {Celegans: WBGene00016167, vps-22, Vacuolar-sorting protein SNF8, [RH, Score=222, Expect=3e-72]} {Smed: dd_Smed_v6_1701_0_1, dd_Smed_v6_1701_0_1, [RH, Score=244, Expect=2e-81]} {RNA1509_14773, RNA1509_20246, RNA1509_33344} {RNA1310_18729, RNA1509_14773, RNA1509_20246, RNA1509_33344} {RNA1509_14773, RNA1509_20246, RNA1509_33344, RNA815_18040}
96. MligTC455_41904 1261 26.28 Mlig455_033790, Mlig455_033840

Neo: -

Age: -

Regeneration-upregulated BL: 1.850

Regeneration-enriched BL: 1.850

TBL1XR1 0.975 - - - 0.975 - -

Mlig455_033790 {REF} {Length: 3142} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=165.9]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=99.7]; Eukaryotic translation initiation factor eIF2A [PF08662.13, score=38.0]; LisH [PF08513.13, score=36.0]} {Human: ENSG00000177565, TBL1XR1, transducin beta like 1 X-linked receptor 1, [RH, Score=718, Expect=0.0]; ENSG00000101849, TBL1X, transducin beta like 1 X-linked, [RH, Score=702, Expect=0.0]; ENSG00000092377, TBL1Y, transducin beta like 1 Y-linked, [RH, Score=693, Expect=0.0]} {Mouse: ENSMUSG00000027630, Tbl1xr1, transducin (beta)-like 1X-linked receptor 1, [RH, Score=723, Expect=0.0]; ENSMUSG00000025246, Tbl1x, transducin (beta)-like 1 X-linked, [RH, Score=709, Expect=0.0]} {Dmel: FBgn0263933, ebi, [RH, Score=584, Expect=0.0]} {Celegans: WBGene00021074, W07E6.2, [Score=118, Expect=2e-28]} {Smed: dd_Smed_v6_3247_0_1, dd_Smed_v6_3247_0_1, [RH, Score=510, Expect=1e-176]} {RNA1509_6947} {RNA1310_1131} {RNA815_1434.1}

Mlig455_033840 {REF} {Length: 3152} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=164.5]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=99.4]; Eukaryotic translation initiation factor eIF2A [PF08662.13, score=37.8]; LisH [PF08513.13, score=36.0]} {Human: ENSG00000177565, TBL1XR1, transducin beta like 1 X-linked receptor 1, [RH, Score=716, Expect=0.0]; ENSG00000101849, TBL1X, transducin beta like 1 X-linked, [RH, Score=700, Expect=0.0]; ENSG00000092377, TBL1Y, transducin beta like 1 Y-linked, [RH, Score=691, Expect=0.0]} {Mouse: ENSMUSG00000027630, Tbl1xr1, transducin (beta)-like 1X-linked receptor 1, [RH, Score=721, Expect=0.0]; ENSMUSG00000025246, Tbl1x, transducin (beta)-like 1 X-linked, [RH, Score=706, Expect=0.0]} {Dmel: FBgn0263933, ebi, [RH, Score=583, Expect=0.0]} {Celegans: WBGene00021074, W07E6.2, [Score=118, Expect=2e-28]} {Smed: dd_Smed_v6_3247_0_1, dd_Smed_v6_3247_0_1, [RH, Score=509, Expect=3e-176]} {RNA1509_49396, RNA1509_6947} {RNA1310_1131, RNA1509_49396, RNA1509_6947} {RNA1509_49396, RNA1509_6947, RNA815_1434.1}
97. MligTC455_42300 310 6.45 Mlig455_003329

Neo: -

Age: -

Region-enriched R5: 1.364/0.02236

GCNA 0.975 - - - 0.975 - - Mlig455_003329 {REF} {Length: 2569} {TRANSSPLICED} {Pfam: SprT-like family [PF10263.11, score=86.7]; SprT-like zinc ribbon domain [PF17283.4, score=21.7]} {Human: ENSG00000147174, GCNA, germ cell nuclear acidic peptidase, [RH, Score=140, Expect=2e-34]} {Dmel: FBgn0023515, CG14814, [RH, Score=163, Expect=1e-41]} {Celegans: WBGene00022694, gcna-1, Germ Cell Nuclear Antigen, [RH, Score=126, Expect=2e-30]} {Smed: dd_Smed_v6_19176_0_2, dd_Smed_v6_19176_0_2, [RH, Score=167, Expect=2e-44]} {RNA1509_15952} {RNA1310_6594} {RNA815_2049}
98. MligTC455_46918 892 18.57 Mlig455_045620

Neo: -

Age: Down-Up-Down

PCTP 0.975 - - - 0.975 - - Mlig455_045620 {REF} {Length: 1430} {TRANSSPLICED} {Pfam: START domain [PF01852.21, score=80.8]} {Human: ENSG00000141179, PCTP, phosphatidylcholine transfer protein, [RH, Score=176, Expect=5e-55]} {Mouse: ENSMUSG00000020553, Pctp, phosphatidylcholine transfer protein, [RH, Score=188, Expect=5e-60]} {Dmel: FBgn0032513, CG6565, [Score=80.9, Expect=1e-17]} {Smed: dd_Smed_v6_3734_0_1, dd_Smed_v6_3734_0_1, [Score=72.8, Expect=2e-15]} {RNA1509_19693, RNA1509_31215} {RNA1310_20753.2, RNA1509_19693, RNA1509_31215} {RNA1509_19693, RNA1509_31215, RNA815_11008}
99. MligTC455_48904 418 8.7 Mlig455_017114

Neo: -

Age: -

ANKRD54 0.975 - - - 0.975 - - Mlig455_017114 {REF} {Length: 1532} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=37.3]; Ankyrin repeat [PF13606.8, score=34.0]; Ankyrin repeats (many copies) [PF13637.8, score=33.4]; Ankyrin repeat [PF00023.32, score=28.5]; Ankyrin repeats (many copies) [PF13857.8, score=28.4]} {Human: ENSG00000100124, ANKRD54, ankyrin repeat domain 54, [RH, Score=75.9, Expect=2e-15]} {Mouse: ENSMUSG00000033055, Ankrd54, ankyrin repeat domain 54, [RH, Score=75.1, Expect=3e-15]} {Dmel: FBgn0036052, CG10809, [RH, Score=70.1, Expect=2e-13]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=53.1, Expect=1e-07]} {Smed: dd_Smed_v6_8330_0_1, dd_Smed_v6_8330_0_1, [Score=56.6, Expect=5e-09]} {RNA1509_30044, RNA1509_49195} {RNA1310_19754.1, RNA1509_30044, RNA1509_49195} {RNA1509_30044, RNA1509_49195, RNA815_39875}
100. MligTC455_26755 93 1.93 Mlig455_022157

Neo: -

Age: Down-Down-Up

NELFB 0.974 - - - - - 0.974 Mlig455_022157 {REF} {Length: 2931} {TRANSSPLICED} {Pfam: Cofactor of BRCA1 (COBRA1) [PF06209.15, score=174.9]} {Human: ENSG00000188986, NELFB, negative elongation factor complex member B, [RH, Score=204, Expect=1e-56]} {Mouse: ENSMUSG00000013465, Nelfb, negative elongation factor complex member B, [RH, Score=209, Expect=4e-58]} {Dmel: FBgn0027553, NELF-B, [RH, Score=199, Expect=4e-55]} {Smed: dd_Smed_v6_9755_0_1, dd_Smed_v6_9755_0_1, [RH, Score=87.0, Expect=1e-17]} {RNA1509_30045} {RNA1310_13572, RNA1509_30045} {RNA1509_30045, RNA815_13418}

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