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Results for MligTC455_19319

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_19319 119 2.49 Mlig455_020560

Neo: -

Age: -

Region-enriched R2: 3.039/0.00928

Mlig455_020560 {REF} {Length: 2838} {TRANSSPLICED} {RNA1509_47202, RNA1509_50453} {RNA1310_16726, RNA1509_47202} {RNA1509_47202, RNA815_9108.1}

Cumulative graph for MligTC455_19319

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -2.007 2.152 0.37777 1.00000
RegionR2 3.039 2.152 0.00031 0.00928
RegionR3 -1.105 2.152 0.21900 0.76069
RegionR4 -1.578 2.152 0.08141 0.26793
RegionR5 -0.172 2.152 0.80390 1.00000
RegionR6 0.161 2.152 0.84038 1.00000
RegionR7 0.936 2.152 0.40317 1.00000
RegionR8 0.727 2.152 0.64811 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -2.678 2.152 0.68558 1.00000
RegenerationR2 -0.19 2.152 0.73700 0.96879
RegenerationR3 1.996 2.152 0.02436 0.28133
RegenerationR4 1.146 2.152 0.13910 0.56073
RegenerationR5 0.346 2.152 0.61109 0.91471
RegenerationR6 0.7 2.152 0.39577 0.73437
RegenerationBL -1.522 2.152 0.28869 0.65073
RegenerationTP 1.318 2.152 0.21550 0.65849


Genes with expression patterns similar to MligTC455_19319

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_19319 119 2.49 Mlig455_020560

Neo: -

Age: -

Region-enriched R2: 3.039/0.00928

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_020560 {REF} {Length: 2838} {TRANSSPLICED} {RNA1509_47202, RNA1509_50453} {RNA1310_16726, RNA1509_47202} {RNA1509_47202, RNA815_9108.1}
2. MligTC455_13044 77 1.6 Mlig455_007417

Neo: -

Age: -

2.663 0.953 - - - 0.851 0.859 Mlig455_007417 {REF} {Length: 3624} {Pfam: Immunoglobulin domain [PF13895.8, score=38.8]; Immunoglobulin V-set domain [PF07686.19, score=26.1]; Immunoglobulin domain [PF13927.8, score=24.9]; Immunoglobulin domain [PF00047.27, score=21.1]} {RNA1509_58583} {RNA1310_59321} {RNA815_25761}
3. MligTC455_35428 140 2.91 Mlig455_056819

Neo: -

Age: -

2.581 0.902 - 0.951 - 0.728 - Mlig455_056819 {REF} {Length: 1592} {NoTransDecoderORF} {RNA1509_35668} {RNA1310_23997.1} {RNA815_18824.1}
4. MligTC455_19450 194 4.05 Mlig455_065775, Mlig455_065798

Neo: -

Age: -

1.787 - - 0.959 - 0.828 -

Mlig455_065775 {REF} {Length: 1864} {Pfam: Innexin [PF00876.20, score=26.9]} {RNA1509_47060} {RNA1310_19756.1} {RNA815_16217}

Mlig455_065798 {REF} {Length: 1809} {Pfam: Innexin [PF00876.20, score=26.9]} {RNA1509_47060} {RNA1310_19756.1} {RNA815_16217}
5. MligTC455_17485 238 4.96 Mlig455_013047

Neo: -

Age: Down-Up-Down

ARNT 1.719 0.954 - 0.765 - - - Mlig455_013047 {REF} {Length: 3020} {TRANSSPLICED} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=49.1]; PAS fold [PF08447.14, score=47.7]; PAS fold [PF00989.27, score=42.6]; PAS fold [PF08448.12, score=29.5]; PAS domain [PF14598.8, score=27.2]} {Human: ENSG00000143437, ARNT, aryl hydrocarbon receptor nuclear translocator, [Score=312, Expect=6e-96]; ENSG00000172379, ARNT2, aryl hydrocarbon receptor nuclear translocator 2, [Score=305, Expect=6e-94]} {Mouse: ENSMUSG00000015522, Arnt, aryl hydrocarbon receptor nuclear translocator, [Score=309, Expect=4e-95]; ENSMUSG00000015709, Arnt2, aryl hydrocarbon receptor nuclear translocator 2, [Score=303, Expect=3e-93]} {Dmel: FBgn0264075, tgo, tango, [Score=325, Expect=2e-102]} {Celegans: WBGene00000095, aha-1, Aryl hydrocarbon receptor nuclear translocator homolog, [Score=256, Expect=1e-78]} {Smed: dd_Smed_v6_9171_0_1, dd_Smed_v6_9171_0_1, [Score=344, Expect=2e-109]} {RNA1509_20140} {RNA1310_12680} {RNA815_8463}
6. MligTC455_13865 71 1.47 Mlig455_054348

Neo: -

Age: logFC(26M/2M)=-0.415

Region-enriched R2: 5.191/0.04459

1.712 0.969 - - - 0.743 - Mlig455_054348 {REF} {Length: 2296} {RNA1509_33524} {RNA1310_15271} {RNA815_24673}
7. MligTC455_47976 51 1.06 Mlig455_043576

Neo: -

Age: Down-Up-Down

ISL1 1.698 0.967 0.731 - - - - Mlig455_043576 {REF} {Length: 3996} {Pfam: LIM domain [PF00412.24, score=99.4]; Homeodomain [PF00046.31, score=55.3]; Homeobox KN domain [PF05920.13, score=23.7]} {Human: ENSG00000016082, ISL1, ISL LIM homeobox 1, [Score=205, Expect=4e-61]} {Mouse: ENSMUSG00000042258, Isl1, ISL1 transcription factor, LIM/homeodomain, [Score=205, Expect=3e-61]} {Dmel: FBgn0003896, tup, tailup, [Score=182, Expect=3e-51]} {Celegans: WBGene00002989, lim-7, CeLIM-7; LIM domain family, [RH, Score=228, Expect=5e-69]} {Smed: dd_Smed_v6_8820_0_1, dd_Smed_v6_8820_0_1, [Score=327, Expect=3e-106]} {RNA1310_20628} {RNA815_37694}
8. MligTC455_27254 34 0.71 Mlig455_045040

Neo: -

Age: -

1.69 0.955 - - - - 0.735 Mlig455_045040 {REF} {Length: 1092} {RNA1509_17721} {RNA1310_36348} {RNA815_19211}
9. MligTC455_17609 87 1.82 Mlig455_059630, Mlig455_059644

Neo: -

Age: Up-Down-Down

GALR2 1.685 - - 0.962 - 0.723 -

Mlig455_059630 {REF} {Length: 3780} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=154.3]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=38.7]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=27.6]; Serpentine type 7TM GPCR chemoreceptor Sru [PF10322.11, score=19.7]} {Human: ENSG00000182687, GALR2, galanin receptor 2, [Score=145, Expect=5e-39]} {Mouse: ENSMUSG00000020793, Galr2, galanin receptor 2, [Score=134, Expect=6e-35]} {Dmel: FBgn0036790, AstC-R1, Allatostatin C receptor 1, [Score=111, Expect=2e-26]} {Celegans: WBGene00013974, npr-9, Galanin-like G-protein coupled receptor npr-9, [Score=102, Expect=2e-23]} {Smed: dd_Smed_v6_15151_0_1, dd_Smed_v6_15151_0_1, [RH, Score=241, Expect=4e-75]} {RNA1310_55640} {RNA815_36728}

Mlig455_059644 {REF} {Length: 3887} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=154.3]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=38.7]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=27.6]; Serpentine type 7TM GPCR chemoreceptor Sru [PF10322.11, score=19.7]} {Human: ENSG00000182687, GALR2, galanin receptor 2, [Score=145, Expect=5e-39]} {Mouse: ENSMUSG00000020793, Galr2, galanin receptor 2, [Score=134, Expect=6e-35]} {Dmel: FBgn0036790, AstC-R1, Allatostatin C receptor 1, [Score=111, Expect=2e-26]} {Celegans: WBGene00013974, npr-9, Galanin-like G-protein coupled receptor npr-9, [Score=102, Expect=2e-23]} {Smed: dd_Smed_v6_15151_0_1, dd_Smed_v6_15151_0_1, [RH, Score=241, Expect=4e-75]} {RNA1310_55640} {RNA815_36728}
10. MligTC455_43500 559 11.65 Mlig455_037594

Neo: -

Age: -

Region-enriched R2: 2.819/0.00033

Regeneration-upregulated R5: 2.517

Regeneration-enriched R5: 2.517

1.676 - 0.717 0.959 - - - Mlig455_037594 {REF} {Length: 1310} {Pfam: Cell-cycle alteration and expression-elevated protein in tumour [PF16566.7, score=19.4]} {RNA1509_30182} {RNA1310_27119, RNA1509_30182} {RNA1509_30182, RNA815_11770}
11. MligTC455_39312 101 2.11 Mlig455_002158

Neo: -

Age: -

CFAP99 1.672 - - - - 0.713 0.959 Mlig455_002158 {REF} {Length: 4740} {Pfam: Thyroglobulin type-1 repeat [PF00086.20, score=82.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=43.8]; Kazal-type serine protease inhibitor domain [PF07648.17, score=35.9]; Kazal-type serine protease inhibitor domain [PF00050.23, score=35.3]; EF-hand domain pair [PF13499.8, score=29.0]; EF-hand domain [PF13405.8, score=27.5]; EF hand [PF00036.34, score=23.2]; EF hand [PF13202.8, score=19.1]} {Human: ENSG00000206113, CFAP99, cilia and flagella associated protein 99, [RH, Score=302, Expect=4e-88]} {Mouse: ENSMUSG00000109572, Cfap99, cilia and flagella associated protein 99, [RH, Score=308, Expect=3e-90]} {Dmel: FBgn0262169, magu, [RH, Score=144, Expect=4e-35]} {Smed: dd_Smed_v6_8538_0_1, dd_Smed_v6_8538_0_1, [RH, Score=342, Expect=5e-103]} {RNA1509_16659} {RNA1310_6756} {RNA815_2531}
12. MligTC455_35103 102 2.12 Mlig455_023928

Neo: -

Age: logFC(26M/2M)=-1.570

Region-enriched R2: 8.161/0.00000

OPN4 1.66 0.955 0.705 - - - - Mlig455_023928 {REF} {Length: 2781} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=179.7]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=34.7]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=28.9]; Olfactory receptor [PF13853.8, score=24.6]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=19.1]} {Human: ENSG00000122375, OPN4, opsin 4, [RH, Score=218, Expect=2e-65]} {Mouse: ENSMUSG00000021799, Opn4, opsin 4 (melanopsin), [RH, Score=225, Expect=1e-68]} {Dmel: FBgn0014019, Rh5, Rhodopsin 5, [RH, Score=222, Expect=2e-68]} {Celegans: WBGene00009619, npr-6, NeuroPeptide Receptor family, [Score=91.3, Expect=4e-20]} {Smed: dd_Smed_v6_15036_0_1, dd_Smed_v6_15036_0_1, [RH, Score=520, Expect=0.0]} {RNA1509_41123} {RNA1310_10673, RNA1509_41123} {RNA1509_41123, RNA815_4962}
13. MligTC455_15684 119 2.47 Mlig455_011251

Neo: -

Age: Up-Down-Up

SNED1 0.98 - - 0.980 - - - Mlig455_011251 {REF} {Length: 1934} {Pfam: EGF-like domain [PF00008.29, score=24.9]} {Human: ENSG00000162804, SNED1, sushi, nidogen and EGF like domains 1, [Score=54.7, Expect=3e-08]; ENSG00000148400, NOTCH1, notch 1, [Score=53.5, Expect=9e-08]; ENSG00000165124, SVEP1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=52.4, Expect=2e-07]} {Mouse: ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=55.1, Expect=1e-08]; ENSMUSG00000038146, Notch3, notch 3, [Score=52.8, Expect=9e-08]} {RNA1509_48141} {RNA1310_40191} {RNA815_46710}
14. MligTC455_19793 281 5.86 Mlig455_066679

Neo: -

Age: -

Region-enriched R2: 2.701/0.03132

PARP3 0.97 - - - - 0.970 - Mlig455_066679 {REF} {Length: 2521} {TRANSSPLICED} {Pfam: Poly(ADP-ribose) polymerase, regulatory domain [PF02877.16, score=139.1]; Poly(ADP-ribose) polymerase catalytic domain [PF00644.22, score=137.9]; WGR domain [PF05406.17, score=94.9]} {Human: ENSG00000041880, PARP3, poly(ADP-ribose) polymerase family member 3, [RH, Score=429, Expect=8e-145]} {Mouse: ENSMUSG00000023249, Parp3, poly (ADP-ribose) polymerase family, member 3, [RH, Score=396, Expect=2e-132]} {Dmel: FBgn0010247, Parp, Poly-(ADP-ribose) polymerase, [Score=256, Expect=9e-75]} {Celegans: WBGene00004049, parp-1, Poly(ADP-ribose) polymerase pme-1, [Score=218, Expect=1e-61]} {Smed: dd_Smed_v6_2611_0_1, dd_Smed_v6_2611_0_1, [RH, Score=265, Expect=8e-85]} {RNA1509_3170} {RNA1310_8330} {RNA815_11984}
15. MligTC455_13599 60 1.26 Mlig455_028520

Neo: -

Age: -

0.968 - - - - - 0.968 Mlig455_028520 {REF} {Length: 1200} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_37463.1} {RNA815_38299}
16. MligTC455_06494 51 1.05 Mlig455_027902

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.607

0.966 - - - - 0.966 - Mlig455_027902 {REF} {Length: 4338} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=45.7]; gag-polyprotein putative aspartyl protease [PF13975.8, score=23.5]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=108, Expect=1e-24]} {RNA1509_40241} {RNA1310_1874.1, RNA1509_40241} {RNA1509_40241, RNA815_16066}
17. MligTC455_51635 152 3.17 Mlig455_042974

Neo: -

Age: Down-Up-Down

DTWD1 0.966 0.966 - - - - - Mlig455_042974 {REF} {Length: 1468} {TRANSSPLICED} {Pfam: DTW domain [PF03942.17, score=92.4]} {Human: ENSG00000104047, DTWD1, DTW domain containing 1, [RH, Score=157, Expect=4e-44]} {Mouse: ENSMUSG00000023330, Dtwd1, DTW domain containing 1, [RH, Score=172, Expect=4e-50]} {Dmel: FBgn0039664, CG2006, [RH, Score=129, Expect=6e-34]} {Celegans: WBGene00175030, Y53C12A.10, [RH, Score=102, Expect=9e-25]} {Smed: dd_Smed_v6_7274_0_1, dd_Smed_v6_7274_0_1, [RH, Score=160, Expect=1e-46]} {RNA1509_34738} {RNA1310_45995.1} {RNA815_42663}
18. MligTC455_39978 270 5.62 Mlig455_052261, Mlig455_052349

Neo: -

Age: Down-Up-Up

Region-enriched R8: 3.650/0.00368
Region-enriched R3: 2.366/0.04725

0.965 - - 0.965 - - -

Mlig455_052261 {REF} {Length: 760} {RNA1310_41850} {RNA815_20313}

Mlig455_052349 {REF} {Length: 710} {RNA1310_41850} {RNA815_20313}
19. MligTC455_26293 89 1.86 Mlig455_041965

Neo: -

Age: Up-Down-Up

Region-enriched R5: 2.793/0.01986

0.962 0.962 - - - - - Mlig455_041965 {REF} {Length: 1464} {NoTransDecoderORF} {RNA1509_2762} {RNA1310_38994} {RNA815_49727}
20. MligTC455_12745 82 1.71 Mlig455_027479

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.603

PRXL2C 0.961 0.961 - - - - - Mlig455_027479 {REF} {Length: 2497} {Pfam: AhpC/TSA antioxidant enzyme [PF13911.8, score=35.1]; AhpC/TSA family [PF00578.23, score=27.1]; Redoxin [PF08534.12, score=25.1]} {Human: ENSG00000158122, PRXL2C, peroxiredoxin like 2C, [RH, Score=137, Expect=1e-39]} {Mouse: ENSMUSG00000021482, Aaed1, AhpC/TSA antioxidant enzyme domain containing 1, [RH, Score=134, Expect=1e-38]} {Smed: dd_Smed_v6_4424_0_1, dd_Smed_v6_4424_0_1, [Score=135, Expect=2e-39]} {RNA1509_42365} {RNA1310_38096, RNA1509_42365} {RNA1509_42365, RNA815_19477}
21. MligTC455_40441 36 0.75 Mlig455_043401

Neo: -

Age: -

0.961 - - 0.961 - - - Mlig455_043401 {REF} {Length: 470} {NoTransDecoderORF} {RNA1509_33654} {RNA1310_22830.1} {RNA815_26998}
22. MligTC455_11124 72 1.5 Mlig455_020487

Neo: -

Age: -

Region-enriched R4: 8.348/0.00117

0.96 0.960 - - - - - Mlig455_020487 {REF} {Length: 1498} {RNA1509_26460} {RNA1310_29093.1, RNA1509_26460} {RNA1509_26460, RNA815_24240}
23. MligTC455_18641 468 9.76 Mlig455_002462

Neo: -

Age: Up-Down-Up

Region-enriched R5: 1.067/0.03966

MFSD13A 0.959 - - - - 0.959 - Mlig455_002462 {REF} {Length: 4524} {Pfam: MFS/sugar transport protein [PF13347.8, score=59.6]} {Human: ENSG00000138111, MFSD13A, major facilitator superfamily domain containing 13A, [RH, Score=324, Expect=3e-104]} {Mouse: ENSMUSG00000025227, Mfsd13a, major facilitator superfamily domain containing 13a, [RH, Score=343, Expect=1e-111]} {Celegans: WBGene00016174, C27H5.4, [Score=100, Expect=2e-22]} {RNA1509_39417, RNA1509_42736, RNA1509_48962} {RNA1310_16644.1, RNA1509_39417, RNA1509_42736, RNA1509_48962} {RNA1509_39417, RNA1509_42736, RNA1509_48962, RNA815_6472.1}
24. MligTC455_23374 134 2.78 Mlig455_016409

Neo: -

Age: -

CDC34 0.959 0.959 - - - - - Mlig455_016409 {REF} {Length: 5157} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=154.3]} {Human: ENSG00000099804, CDC34, cell division cycle 34, [RH, Score=280, Expect=2e-95]; ENSG00000107341, UBE2R2, ubiquitin conjugating enzyme E2 R2, [RH, Score=277, Expect=4e-94]} {Mouse: ENSMUSG00000020307, Cdc34, cell division cycle 34, [RH, Score=279, Expect=6e-95]; ENSMUSG00000036241, Ube2r2, ubiquitin-conjugating enzyme E2R 2, [RH, Score=277, Expect=3e-94]; ENSMUSG00000020870, Cdc34b, cell division cycle 34B, [RH, Score=273, Expect=1e-92]} {Dmel: FBgn0036516, CG7656, [RH, Score=281, Expect=1e-94]} {Celegans: WBGene00006702, ubc-3, UBiquitin Conjugating enzyme, [RH, Score=264, Expect=3e-89]} {Smed: dd_Smed_v6_8367_0_1, dd_Smed_v6_8367_0_1, [RH, Score=259, Expect=3e-87]} {RNA1509_31608} {RNA1310_20391} {RNA815_14254}
25. MligTC455_49026 215 4.48 Mlig455_037206

Neo: -

Age: Down-Up-Down

HSPG2 0.959 - - 0.959 - - - Mlig455_037206 {REF} {Length: 4399} {Pfam: Immunoglobulin domain [PF13927.8, score=184.9]; Immunoglobulin domain [PF13895.8, score=134.5]; Immunoglobulin I-set domain [PF07679.18, score=112.6]; Immunoglobulin domain [PF00047.27, score=95.1]; Immunoglobulin V-set domain [PF07686.19, score=61.1]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=42.0]; Fibronectin type III domain [PF00041.23, score=37.5]; Immunoglobulin domain [PF18452.3, score=35.0]; C17orf99 Ig domain [PF17736.3, score=23.3]} {Human: ENSG00000142798, HSPG2, heparan sulfate proteoglycan 2, [Score=117, Expect=8e-26]} {Mouse: ENSMUSG00000055632, Hmcn2, hemicentin 2, [Score=132, Expect=2e-30]} {Dmel: FBgn0000547, ed, echinoid, [Score=217, Expect=3e-57]} {Celegans: WBGene00018215, igcm-1, ImmunoGlobulin-like Cell adhesion Molecule family, [Score=138, Expect=6e-33]} {Smed: dd_Smed_v6_13903_0_1, dd_Smed_v6_13903_0_1, [Score=162, Expect=2e-40]} {RNA1509_31910} {RNA1310_43699} {RNA815_44505}
26. MligTC455_30266 111 2.32 Mlig455_052913

Neo: -

Age: -

0.958 - - 0.958 - - - Mlig455_052913 {REF} {Length: 741} {RNA1509_12647} {RNA1310_70871} {RNA815_7825}
27. MligTC455_33278 117 2.43 Mlig455_046422

Neo: -

Age: -

0.958 - - 0.958 - - - Mlig455_046422 {REF} {Length: 1043} {RNA1509_50995} {RNA1310_34473, RNA1509_50995} {RNA1509_50995, RNA815_17694}
28. MligTC455_49586 392 8.16 Mlig455_057477

Neo: -

Age: logFC(26M/2M)=0.641

0.958 - - 0.958 - - - Mlig455_057477 {REF} {Length: 1706} {TRANSSPLICED} {Pfam: Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=35.9]; Prokaryotic RING finger family 4 [PF14447.8, score=23.7]} {RNA1509_9323} {RNA1310_4491.3} {RNA815_1092}
29. MligTC455_27001 269 5.6 Mlig455_015615

Neo: -

Age: -

NAV2 0.957 0.957 - - - - - Mlig455_015615 {REF} {Length: 5528} {TRANSSPLICED} {Human: ENSG00000166833, NAV2, neuron navigator 2, [Score=511, Expect=1e-151]} {Mouse: ENSMUSG00000052512, Nav2, neuron navigator 2, [Score=501, Expect=2e-148]; ENSMUSG00000020181, Nav3, neuron navigator 3, [Score=476, Expect=6e-140]} {Dmel: FBgn0263873, sick, sickie, [Score=358, Expect=1e-102]} {Celegans: WBGene00006788, unc-53, Adapter protein unc-53, [Score=140, Expect=3e-33]} {Smed: dd_Smed_v6_7701_0_2, dd_Smed_v6_7701_0_2, [Score=433, Expect=2e-128]} {RNA1509_12417} {RNA1310_596.1} {RNA815_2589}
30. MligTC455_30852 46 0.96 Mlig455_019345, Mlig455_019563, Mlig455_059135

Neo: -

Age: -

GRIA2, GRIK2, GRIK4 0.956 0.956 - - - - -

Mlig455_019345 {REF} {Length: 3399} {Pfam: Ligand-gated ion channel [PF00060.28, score=95.4]; Receptor family ligand binding region [PF01094.30, score=56.8]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=25.8]; Iron-containing alcohol dehydrogenase [PF13685.8, score=21.9]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=159, Expect=1e-39]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=157, Expect=9e-39]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=159, Expect=7e-40]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=155, Expect=2e-38]} {Dmel: FBgn0039927, CG11155, [Score=160, Expect=3e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [RH, Score=281, Expect=4e-87]} {RNA1509_10728} {RNA1310_122.1} {RNA815_8415.1}

Mlig455_019563 {REF} {Length: 2692} {Pfam: Ligand-gated ion channel [PF00060.28, score=91.5]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=98.6, Expect=6e-23]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=95.9, Expect=5e-22]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=94.7, Expect=1e-21]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=96.7, Expect=2e-22]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=95.9, Expect=3e-22]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=94.7, Expect=9e-22]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=92.8, Expect=4e-21]} {Dmel: FBgn0038837, CG3822, [Score=99.4, Expect=2e-23]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=92.8, Expect=2e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=176, Expect=4e-53]} {RNA1310_21734.1} {RNA815_52393}

Mlig455_059135 {REF} {Length: 3434} {Pfam: Receptor family ligand binding region [PF01094.30, score=58.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=45.1]; Iron-containing alcohol dehydrogenase [PF13685.8, score=23.1]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=71.6, Expect=2e-12]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=70.5, Expect=3e-12]} {Dmel: FBgn0038837, CG3822, [Score=62.0, Expect=1e-09]} {Celegans: WBGene00001617, glr-6, GLutamate Receptor family (AMPA), [Score=68.6, Expect=6e-12]} {Smed: dd_Smed_v6_41723_0_2, dd_Smed_v6_41723_0_2, [Score=85.1, Expect=8e-18]} {RNA1509_10728} {RNA1310_122.1} {RNA815_8415.1}
31. MligTC455_46512 2553 53.19 Mlig455_035211

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.719

Region-enriched R3: 4.974/0.00000
Region-enriched R2: 3.362/0.00840

0.956 0.956 - - - - - Mlig455_035211 {REF} {Length: 699} {RNA1509_22822, RNA1509_5889} {RNA1310_52884, RNA1509_22822, RNA1509_5889} {RNA1509_22822, RNA1509_5889, RNA815_23505}
32. MligTC455_20024 159 3.31 Mlig455_069868

Neo: Irradiation

Age: -

NSD2 0.955 0.955 - - - - - Mlig455_069868 {REF} {Length: 3452} {Pfam: PWWP domain [PF00855.19, score=106.0]; PHD-finger [PF00628.31, score=32.7]; AWS domain [PF17907.3, score=22.2]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=18.4]} {Human: ENSG00000109685, NSD2, nuclear receptor binding SET domain protein 2, [Score=209, Expect=2e-54]} {Mouse: ENSMUSG00000057406, Nsd2, nuclear receptor binding SET domain protein 2, [Score=209, Expect=8e-55]; ENSMUSG00000021488, Nsd1, nuclear receptor-binding SET-domain protein 1, [Score=200, Expect=1e-51]} {Dmel: FBgn0039559, NSD, Nuclear receptor binding SET domain protein, [Score=172, Expect=2e-43]} {Smed: dd_Smed_v6_4755_0_2, dd_Smed_v6_4755_0_2, [Score=186, Expect=6e-49]} {RNA1509_22588} {RNA1310_10794.1} {RNA815_16118}
33. MligTC455_39766 175 3.66 Mlig455_047720

Neo: Germline

Age: Up-Down-Down

0.955 - - 0.955 - - - Mlig455_047720 {REF} {Length: 5216} {NoTransDecoderORF} {RNA1509_22260} {RNA1310_4827.1} {RNA815_20146}
34. MligTC455_38720 72 1.5 Mlig455_065562

Neo: -

Age: Up-Down-Down

COL4A6 0.954 - - - 0.954 - - Mlig455_065562 {REF} {Length: 6263} {Pfam: Collagen triple helix repeat (20 copies) [PF01391.20, score=613.8]; C-terminal tandem repeated domain in type 4 procollagen [PF01413.21, score=202.1]} {Human: ENSG00000197565, COL4A6, collagen type IV alpha 6 chain, [Score=502, Expect=6e-149]} {Mouse: ENSMUSG00000031273, Col4a6, collagen, type IV, alpha 6, [Score=514, Expect=3e-153]; ENSMUSG00000116510, Col4a6, collagen, type IV, alpha 6, [Score=514, Expect=3e-153]} {Dmel: FBgn0016075, vkg, viking, [Score=596, Expect=0.0]} {Celegans: WBGene00001263, emb-9, Collagen alpha-1(IV) chain, [Score=583, Expect=1e-177]} {Smed: dd_Smed_v6_2337_0_1, dd_Smed_v6_2337_0_1, [Score=738, Expect=0.0]} {RNA1509_23572, RNA1509_35895, RNA1509_45361, RNA1509_5346} {RNA1310_692.1, RNA1509_23572, RNA1509_35895, RNA1509_45361} {RNA1509_23572, RNA1509_35895, RNA1509_45361, RNA815_573}
35. MligTC455_39111 95 1.98 Mlig455_049851, Mlig455_070371

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.790

NOTCH3 0.953 - - - - - 0.953

Mlig455_049851 {REF} {Length: 1412} {RNA1509_19091} {RNA1310_19560} {RNA815_3356.1}

Mlig455_070371 {REF} {Length: 2329} {Human: ENSG00000074181, NOTCH3, notch 3, [Score=51.2, Expect=4e-06]; ENSG00000165124, SVEP1, sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, [Score=50.4, Expect=6e-06]} {Mouse: ENSMUSG00000038146, Notch3, notch 3, [Score=50.1, Expect=5e-06]} {RNA1509_19091} {RNA1310_14363.1} {RNA815_3356.1}
36. MligTC455_39313 100 2.07 Mlig455_002259

Neo: -

Age: -

SMOC1 0.953 - - - - - 0.953 Mlig455_002259 {REF} {Length: 2954} {Pfam: Thyroglobulin type-1 repeat [PF00086.20, score=83.6]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=49.9]; Kazal-type serine protease inhibitor domain [PF07648.17, score=37.6]; Kazal-type serine protease inhibitor domain [PF00050.23, score=36.6]; EF-hand domain [PF13405.8, score=31.1]; EF-hand domain pair [PF13499.8, score=30.2]; EF hand [PF00036.34, score=26.6]; EF hand [PF13202.8, score=20.9]} {Human: ENSG00000198732, SMOC1, SPARC related modular calcium binding 1, [RH, Score=80.5, Expect=3e-15]} {Mouse: ENSMUSG00000021136, Smoc1, SPARC related modular calcium binding 1, [RH, Score=82.4, Expect=4e-16]} {Dmel: FBgn0262169, magu, [RH, Score=145, Expect=4e-36]} {RNA1509_16659} {RNA1310_6756, RNA1509_16659} {RNA1509_16659, RNA815_13591}
37. MligTC455_53662 2784 58 Mlig455_007977, Mlig455_015600

Neo: -

Age: logFC(26M/2M)=-0.407

0.953 - - - - - 0.953

Mlig455_007977 {REF} {Length: 2162} {Smed: dd_Smed_v6_1161_1_1, dd_Smed_v6_1161_1_1, [RH, Score=68.6, Expect=5e-13]} {RNA1509_2354, RNA1509_33456} {RNA1310_13288.1, RNA1509_33456} {RNA1509_33456, RNA815_8569}

Mlig455_015600 {REF} {Length: 1981} {Smed: dd_Smed_v6_1161_1_1, dd_Smed_v6_1161_1_1, [RH, Score=68.6, Expect=5e-13]} {RNA1509_10769, RNA1509_2354, RNA1509_38909, RNA1509_39678} {RNA1310_13288.1, RNA1509_10769, RNA1509_2354, RNA1509_38909, RNA1509_39678} {RNA1509_10769, RNA1509_2354, RNA1509_38909, RNA1509_39678, RNA815_8569}
38. MligTC455_02244 25 0.53 Mlig455_026007, Mlig455_070432

Neo: -

Age: -

0.952 0.952 - - - - -

Mlig455_026007 {REF} {Length: 604} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=91.3, Expect=3e-24]} {RNA1310_143494}

Mlig455_070432 {REF} {Length: 1561} {Dmel: FBgn0050419, CG30419, [RH, Score=61.6, Expect=1e-11]} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [RH, Score=112, Expect=2e-32]} {RNA1310_143494}
39. MligTC455_39706 142 2.95 Mlig455_025725

Neo: -

Age: -

TCF4 0.952 0.952 - - - - - Mlig455_025725 {REF} {Length: 3387} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=34.9]} {Human: ENSG00000196628, TCF4, transcription factor 4, [RH, Score=159, Expect=7e-41]; ENSG00000071564, TCF3, transcription factor 3, [RH, Score=157, Expect=1e-39]; ENSG00000140262, TCF12, transcription factor 12, [RH, Score=157, Expect=6e-41]} {Mouse: ENSMUSG00000020167, Tcf3, transcription factor 3, [RH, Score=160, Expect=8e-41]; ENSMUSG00000053477, Tcf4, transcription factor 4, [RH, Score=158, Expect=5e-41]; ENSMUSG00000032228, Tcf12, transcription factor 12, [RH, Score=157, Expect=2e-40]} {Dmel: FBgn0267821, da, daughterless, [RH, Score=154, Expect=9e-39]} {Celegans: WBGene00001949, hlh-2, Helix Loop Helix, [RH, Score=108, Expect=6e-25]} {Smed: dd_Smed_v6_5579_0_1, dd_Smed_v6_5579_0_1, [RH, Score=167, Expect=3e-43]} {RNA1509_43202} {RNA1310_31462} {RNA815_24954}
40. MligTC455_25111 26 0.55 Mlig455_010805

Neo: -

Age: Up-Down-Down

FAT4 0.951 0.951 - - - - - Mlig455_010805 {REF} {Length: 5016} {Pfam: Cadherin domain [PF00028.19, score=101.0]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=97.1, Expect=4e-20]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=96.3, Expect=5e-20]} {Dmel: FBgn0284247, ds, dachsous, [Score=90.5, Expect=2e-18]} {Celegans: WBGene00019994, cdh-1, CaDHerin family, [Score=68.2, Expect=1e-11]} {Smed: dd_Smed_v6_19816_0_1, dd_Smed_v6_19816_0_1, [Score=133, Expect=1e-32]} {RNA1509_48512} {RNA1310_12575, RNA1509_48512} {RNA1509_48512, RNA815_36009}
41. MligTC455_46018 256 5.34 Mlig455_004929, Mlig455_019730

Neo: -

Age: -

Region-enriched R2: 3.065/0.00629

OTX1 0.951 - - 0.951 - - -

Mlig455_004929 {REF} {Length: 2609} {Pfam: Homeodomain [PF00046.31, score=71.5]} {Human: ENSG00000115507, OTX1, orthodenticle homeobox 1, [RH, Score=135, Expect=5e-36]} {Mouse: ENSMUSG00000005917, Otx1, orthodenticle homeobox 1, [RH, Score=135, Expect=5e-36]} {Dmel: FBgn0004102, oc, ocelliless, [RH, Score=120, Expect=1e-29]} {Celegans: WBGene00006652, ttx-1, Homeodomain protein TTX-1, [RH, Score=118, Expect=6e-30]} {Smed: dd_Smed_v6_15516_0_1, dd_Smed_v6_15516_0_1, [RH, Score=90.1, Expect=1e-19]} {RNA1509_34770} {RNA1310_12365.2} {RNA815_33468}

Mlig455_019730 {REF} {Length: 2056} {Pfam: Homeodomain [PF00046.31, score=73.3]} {Human: ENSG00000115507, OTX1, orthodenticle homeobox 1, [RH, Score=135, Expect=8e-36]} {Mouse: ENSMUSG00000005917, Otx1, orthodenticle homeobox 1, [RH, Score=135, Expect=6e-36]} {Dmel: FBgn0004102, oc, ocelliless, [RH, Score=121, Expect=8e-30]} {Celegans: WBGene00006652, ttx-1, Homeodomain protein TTX-1, [Score=122, Expect=4e-31]} {Smed: dd_Smed_v6_63359_0_2, dd_Smed_v6_63359_0_2, [Score=93.2, Expect=5e-23]} {RNA1509_34770} {RNA1310_12365.2} {RNA815_33468}
42. MligTC455_49482 141 2.93 Mlig455_025488, Mlig455_025510

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.130

Region-enriched R7: 2.725/0.03700

0.95 - - - - - 0.950

Mlig455_025488 {REF} {Length: 729} {Smed: dd_Smed_v6_12479_0_1, dd_Smed_v6_12479_0_1, [Score=65.1, Expect=8e-15]} {RNA1509_30340} {RNA1310_59879} {RNA815_30690}

Mlig455_025510 {REF} {Length: 553} {Smed: dd_Smed_v6_12479_0_1, dd_Smed_v6_12479_0_1, [Score=65.1, Expect=8e-15]} {RNA1509_30340} {RNA1310_59879} {RNA815_30690}

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