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Results for MligTC455_19937

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_19937 67 1.40 Mlig455_048004

Neo: -

Age: Down-Up-Down

Region-enriched R4: 5.334/0.01237

NKX2-2 Mlig455_048004 {REF} {Length: 2666} {Pfam: Homeodomain [PF00046.31, score=72.6]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [Score=119, Expect=2e-31]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [Score=119, Expect=1e-31]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [Score=112, Expect=1e-27]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=95.5, Expect=9e-23]} {Smed: dd_Smed_v6_2716_0_3, dd_Smed_v6_2716_0_3, [Score=118, Expect=4e-30]} {RNA1509_27298} {RNA1310_16689.1} {RNA815_30453}

Cumulative graph for MligTC455_19937

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.861 1.731 1.00000 1.00000
RegionR2 2.586 1.731 0.09476 0.37758
RegionR3 2.744 1.731 0.01616 0.20657
RegionR4 5.334 1.731 0.00125 0.01237
RegionR5 -0.211 1.731 0.59458 0.95259
RegionR6 -4.125 1.731 1.00000 1.00000
RegionR7 -4.065 1.731 1.00000 1.00000
RegionR8 -4.125 1.731 1.00000 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -2.01 1.731 0.99992 1.00000
RegenerationR2 -1.42 1.731 0.06275 0.41119
RegenerationR3 -0.369 1.731 0.61837 0.91584
RegenerationR4 -2.705 1.731 0.02397 0.24803
RegenerationR5 -2.151 1.731 0.08143 0.44287
RegenerationR6 0.538 1.731 0.99988 1.00000
RegenerationBL 5.719 1.731 0.00874 0.09261
RegenerationTP 2.359 1.731 0.38987 0.82243


Genes with expression patterns similar to MligTC455_19937

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_19937 67 1.4 Mlig455_048004

Neo: -

Age: Down-Up-Down

Region-enriched R4: 5.334/0.01237

NKX2-2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_048004 {REF} {Length: 2666} {Pfam: Homeodomain [PF00046.31, score=72.6]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [Score=119, Expect=2e-31]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [Score=119, Expect=1e-31]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [Score=112, Expect=1e-27]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=95.5, Expect=9e-23]} {Smed: dd_Smed_v6_2716_0_3, dd_Smed_v6_2716_0_3, [Score=118, Expect=4e-30]} {RNA1509_27298} {RNA1310_16689.1} {RNA815_30453}
2. MligTC455_19938 250 5.2 Mlig455_063706

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.458

Region-enriched R3: 3.513/0.03723

NKX2-2 4.444 0.984 0.961 0.729 0.808 - 0.962 Mlig455_063706 {REF} {Length: 2739} {Pfam: Homeodomain [PF00046.31, score=72.6]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [Score=119, Expect=3e-31]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [Score=119, Expect=1e-31]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [Score=112, Expect=2e-27]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=95.9, Expect=8e-23]} {Smed: dd_Smed_v6_2716_0_4, dd_Smed_v6_2716_0_4, [Score=118, Expect=4e-30]} {RNA1509_27298} {RNA1310_16689.1, RNA1509_27298} {RNA1509_27298, RNA815_30453}
3. MligTC455_25412 199 4.15 Mlig455_008720, Mlig455_063581

Neo: -

Age: -

Region-enriched R2: 7.484/0.00035

CNBD2 3.449 0.969 0.811 - 0.808 - 0.861

Mlig455_008720 {REF} {Length: 2602} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=82.1]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [Score=52.4, Expect=3e-06]} {Smed: dd_Smed_v6_13623_0_1, dd_Smed_v6_13623_0_1, [Score=241, Expect=1e-69]} {RNA1509_50931} {RNA1310_3304} {RNA815_12767}

Mlig455_063581 {REF} {Length: 2668} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=82.3]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [Score=52.4, Expect=3e-06]} {Smed: dd_Smed_v6_13623_0_1, dd_Smed_v6_13623_0_1, [Score=241, Expect=7e-70]} {RNA1509_50931} {RNA1310_3304} {RNA815_12767}
4. MligTC455_43561 47 0.98 Mlig455_019076, Mlig455_064291

Neo: -

Age: -

ASIC3 3.431 0.964 0.774 - 0.945 - 0.748

Mlig455_019076 {REF} {Length: 2496} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=274.8]} {Human: ENSG00000213199, ASIC3, acid sensing ion channel subunit 3, [RH, Score=122, Expect=5e-29]} {Mouse: ENSMUSG00000020704, Asic2, acid-sensing (proton-gated) ion channel 2, [Score=114, Expect=1e-26]} {Dmel: FBgn0030795, ppk28, pickpocket 28, [Score=58.5, Expect=9e-09]} {Celegans: WBGene00012137, asic-2, Degenerin-like protein asic-2, [Score=133, Expect=5e-33]} {Smed: dd_Smed_v6_17021_0_1, dd_Smed_v6_17021_0_1, [Score=127, Expect=4e-31]} {RNA1509_37765} {RNA1310_15854} {RNA815_39159}

Mlig455_064291 {REF} {Length: 2206} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=52.6]} {Celegans: WBGene00012137, asic-2, Degenerin-like protein asic-2, [Score=46.6, Expect=1e-06]} {Smed: dd_Smed_v6_26469_0_1, dd_Smed_v6_26469_0_1, [Score=47.8, Expect=1e-07]} {RNA1509_37765} {RNA1310_15854} {RNA815_28789}
5. MligTC455_18540 1213 25.28 Mlig455_003235

Neo: -

Age: -

Region-specific R2: 5.238

Region-enriched R2: 4.787/0.00000
Region-enriched R3: 3.982/0.00000

SFRP2 3.418 0.861 0.820 - 0.776 - 0.961 Mlig455_003235 {REF} {Length: 1691} {TRANSSPLICED} {Pfam: Fz domain [PF01392.24, score=86.0]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [RH, Score=167, Expect=4e-46]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [RH, Score=165, Expect=2e-45]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=101, Expect=8e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=1e-44]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [RH, Score=157, Expect=1e-42]} {RNA1509_5709} {RNA1310_15264} {RNA815_7067}
6. MligTC455_18539 1250 26.03 Mlig455_003030

Neo: -

Age: logFC(26M/2M)=-0.308

Region-specific R2: 5.210

Region-enriched R2: 4.715/0.00000
Region-enriched R3: 3.959/0.00000

SFRP2 3.417 0.845 0.827 - 0.778 - 0.967 Mlig455_003030 {REF} {Length: 2108} {Pfam: Fz domain [PF01392.24, score=88.0]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [RH, Score=166, Expect=7e-48]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [RH, Score=165, Expect=2e-47]; ENSMUSG00000031548, Sfrp1, secreted frizzled-related protein 1, [RH, Score=157, Expect=2e-44]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=100, Expect=2e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=6e-47]} {Smed: dd_Smed_v6_8832_0_1, dd_Smed_v6_8832_0_1, [RH, Score=153, Expect=4e-43]} {RNA1509_32854, RNA1509_44148, RNA1509_5709} {RNA1310_15264, RNA1509_32854, RNA1509_44148, RNA1509_5709} {RNA1509_32854, RNA1509_44148, RNA1509_5709, RNA815_7067}
7. MligTC455_32563 900 18.74 Mlig455_021721

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.879

Region-enriched R2: 4.965/0.00011
Region-enriched R3: 4.190/0.00008

3.399 0.928 0.769 - 0.957 - 0.745 Mlig455_021721 {REF} {Length: 1079} {RNA1509_570} {RNA1310_40828} {RNA815_5866.1}
8. MligTC455_33442 39 0.81 Mlig455_039767

Neo: -

Age: -

3.298 0.956 0.783 0.762 0.797 - - Mlig455_039767 {REF} {Length: 1975} {RNA1310_42391}
9. MligTC455_18161 771 16.05 Mlig455_031626, Mlig455_048205

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.318/0.00160

3.288 0.960 0.785 - 0.833 - 0.710

Mlig455_031626 {REF} {Length: 835} {TRANSSPLICED} {RNA1509_48514} {RNA1310_56583, RNA1509_48514} {RNA1509_48514, RNA815_34758}

Mlig455_048205 {REF} {Length: 651} {RNA1509_48514} {RNA1310_56583} {RNA815_34758}
10. MligTC455_43676 56 1.16 Mlig455_058053, Mlig455_058096

Neo: -

Age: -

3.276 0.963 0.825 - 0.715 - 0.773

Mlig455_058053 {REF} {Length: 391} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_102705} {RNA815_52459}

Mlig455_058096 {REF} {Length: 1983} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=51.3]} {Smed: dd_Smed_v6_9783_0_1, dd_Smed_v6_9783_0_1, [Score=90.1, Expect=1e-19]} {RNA1509_1472} {RNA1310_25467} {RNA815_39314}
11. MligTC455_28994 66 1.38 Mlig455_030538

Neo: -

Age: Up-Down-Up

SIX1 2.724 - 0.870 - 0.967 - 0.887 Mlig455_030538 {REF} {Length: 3445} {TRANSSPLICED} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=146.9]; Homeodomain [PF00046.31, score=55.9]; Homeobox KN domain [PF05920.13, score=48.0]} {Human: ENSG00000126778, SIX1, SIX homeobox 1, [Score=313, Expect=1e-103]; ENSG00000170577, SIX2, SIX homeobox 2, [Score=307, Expect=4e-101]} {Mouse: ENSMUSG00000051367, Six1, sine oculis-related homeobox 1, [Score=313, Expect=9e-104]; ENSMUSG00000024134, Six2, sine oculis-related homeobox 2, [Score=307, Expect=2e-101]} {Dmel: FBgn0003460, so, sine oculis, [Score=303, Expect=3e-98]} {Celegans: WBGene00000454, ceh-33, Homeobox protein ceh-33, [RH, Score=246, Expect=3e-78]} {Smed: dd_Smed_v6_15436_0_1, dd_Smed_v6_15436_0_1, [RH, Score=328, Expect=2e-107]} {RNA1509_55511} {RNA1310_27700} {RNA815_16067}
12. MligTC455_04170 65 1.36 Mlig455_000555, Mlig455_030353

Neo: -

Age: -

FGG 2.667 0.973 - - 0.941 - 0.753

Mlig455_000555 {REF} {Length: 1133} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=125.0]} {Human: ENSG00000171557, FGG, fibrinogen gamma chain, [Score=103, Expect=3e-24]; ENSG00000120332, TNN, tenascin N, [Score=98.2, Expect=3e-22]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=102, Expect=6e-25]; ENSMUSG00000026938, Fcna, ficolin A, [Score=99.4, Expect=1e-23]; ENSMUSG00000033860, Fgg, fibrinogen gamma chain, [Score=98.2, Expect=9e-23]; ENSMUSG00000026725, Tnn, tenascin N, [Score=98.2, Expect=2e-22]} {Dmel: FBgn0051832, CG31832, [Score=88.2, Expect=2e-20]} {Celegans: WBGene00020516, T15B7.1, [Score=62.4, Expect=8e-11]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=72.4, Expect=4e-14]} {RNA1310_33683.2} {RNA815_41841}

Mlig455_030353 {REF} {Length: 1214} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=126.3]} {Human: ENSG00000171557, FGG, fibrinogen gamma chain, [Score=103, Expect=3e-24]; ENSG00000120332, TNN, tenascin N, [Score=99.4, Expect=3e-22]; ENSG00000160339, FCN2, ficolin 2, [Score=98.2, Expect=6e-23]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=102, Expect=1e-24]; ENSMUSG00000026938, Fcna, ficolin A, [Score=100, Expect=1e-23]; ENSMUSG00000026725, Tnn, tenascin N, [Score=99.0, Expect=2e-22]; ENSMUSG00000033860, Fgg, fibrinogen gamma chain, [Score=99.0, Expect=9e-23]} {Dmel: FBgn0051832, CG31832, [Score=92.0, Expect=9e-22]} {Celegans: WBGene00020516, T15B7.1, [Score=63.2, Expect=4e-11]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=75.9, Expect=4e-15]} {RNA1310_33683.2} {RNA815_41841}
13. MligTC455_51029 340 7.09 Mlig455_056736

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.541

2.665 0.962 - - 0.965 - 0.738 Mlig455_056736 {REF} {Length: 850} {RNA1509_4527} {RNA1310_27536} {RNA815_19650}
14. MligTC455_36287 99 2.07 Mlig455_049197

Neo: -

Age: Down-Down-Up

Region-enriched R3: 4.053/0.01407

2.663 0.861 - - 0.970 - 0.832 Mlig455_049197 {REF} {Length: 736} {Pfam: CUB domain [PF00431.22, score=28.0]} {RNA1509_1672} {RNA1310_53620} {RNA815_26829}
15. MligTC455_34692 37 0.77 Mlig455_017379

Neo: -

Age: -

2.651 0.973 - - 0.829 - 0.849 Mlig455_017379 {REF} {Length: 579} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_10294} {RNA1310_2672} {RNA815_25099}
16. MligTC455_53937 44 0.92 Mlig455_021975, Mlig455_022028

Neo: -

Age: -

2.622 0.980 0.894 - - - 0.748

Mlig455_021975 {REF} {Length: 631} {NoTransDecoderORF} {RNA1310_130902}

Mlig455_022028 {REF} {Length: 192} {NoTransDecoderORF} {RNA1310_130902}
17. MligTC455_51028 379 7.9 Mlig455_013974, Mlig455_034999

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.689

Region-enriched R2: 4.550/0.00627
Region-enriched R3: 3.132/0.04127

2.609 0.891 - - 0.958 - 0.760

Mlig455_013974 {REF} {Length: 857} {RNA1509_4527} {RNA1310_27536} {RNA815_19650}

Mlig455_034999 {REF} {Length: 847} {RNA1509_4527} {RNA1310_27536} {RNA815_19650}
18. MligTC455_18395 39 0.8 Mlig455_053780

Neo: -

Age: -

MECOM 2.585 - - 0.716 0.968 - 0.901 Mlig455_053780 {REF} {Length: 1146} {Pfam: Zinc-finger double domain [PF13465.8, score=63.0]; Zinc finger, C2H2 type [PF00096.28, score=48.8]; C2H2-type zinc finger [PF13894.8, score=33.6]; C2H2-type zinc-finger domain [PF13909.8, score=26.9]; Drought induced 19 protein (Di19), zinc-binding [PF05605.14, score=23.9]; GAGA factor [PF09237.13, score=18.9]} {Human: ENSG00000085276, MECOM, MDS1 and EVI1 complex locus, [Score=133, Expect=6e-34]; ENSG00000142611, PRDM16, PR/SET domain 16, [Score=132, Expect=8e-34]} {Mouse: ENSMUSG00000039410, Prdm16, PR domain containing 16, [Score=133, Expect=5e-34]; ENSMUSG00000027684, Mecom, MDS1 and EVI1 complex locus, [Score=133, Expect=3e-34]} {Dmel: FBgn0032707, CG10348, [Score=132, Expect=3e-34]} {Celegans: WBGene00001207, egl-43, Egl-43, [RH, Score=97.8, Expect=3e-23]} {Smed: dd_Smed_v6_22685_0_1, dd_Smed_v6_22685_0_1, [Score=134, Expect=1e-36]} {RNA1310_48534} {RNA815_4264.1}
19. MligTC455_24951 220 4.58 Mlig455_052169

Neo: -

Age: -

Region-specific R2: 4.554

Region-enriched R2: 4.264/0.00008

Regeneration-downregulated R2: -1.743

Regeneration-depleted R2: -1.743

CCDC169 2.581 0.973 0.783 - 0.825 - - Mlig455_052169 {REF} {Length: 1369} {Pfam: Domain of unknown function (DUF4600) [PF15372.8, score=97.2]} {Human: ENSG00000242715, CCDC169, coiled-coil domain containing 169, [RH, Score=82.8, Expect=6e-19]} {Mouse: ENSMUSG00000048655, Ccdc169, coiled-coil domain containing 169, [RH, Score=94.0, Expect=3e-23]} {Smed: dd_Smed_v6_12011_0_1, dd_Smed_v6_12011_0_1, [RH, Score=207, Expect=9e-68]} {RNA1509_8270} {RNA1310_23029} {RNA815_11545}
20. MligTC455_03731 113 2.35 Mlig455_066791

Neo: -

Age: -

2.575 0.960 0.800 - 0.815 - - Mlig455_066791 {REF} {Length: 1679} {Smed: dd_Smed_v6_13648_0_1, dd_Smed_v6_13648_0_1, [RH, Score=79.7, Expect=2e-16]} {RNA1509_58026} {RNA1310_23180, RNA1509_58026} {RNA1509_58026, RNA815_34008}
21. MligTC455_31240 329 6.85 Mlig455_010150

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.167

Region-enriched R4: 6.247/0.01251

2.565 0.972 - - 0.828 - 0.765 Mlig455_010150 {REF} {Length: 557} {RNA1509_16524, RNA1509_26056} {RNA1310_74791.1, RNA1509_16524} {RNA1509_16524, RNA815_37646}
22. MligTC455_52122 1435 29.9 Mlig455_035226, Mlig455_035273

Neo: -

Age: -

Region-enriched R3: 3.936/0.00000
Region-enriched R2: 3.858/0.00018

2.563 0.826 - - 0.965 - 0.772

Mlig455_035226 {REF} {Length: 725} {TRANSSPLICED} {RNA1509_39421} {RNA1310_8553.2, RNA1509_39421} {RNA1509_39421, RNA815_2974.1}

Mlig455_035273 {REF} {Length: 1422} {RNA1509_24257, RNA1509_39421} {RNA1310_8553.2, RNA1509_24257} {RNA1509_24257, RNA815_2974.1}
23. MligTC455_47113 8202 170.88 Mlig455_044572

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.259

Region-enriched R2: 5.618/0.00000
Region-enriched R3: 4.390/0.00000

Regeneration-downregulated R2: -4.863

Regeneration-depleted R2: -4.863

2.559 - 0.735 - 0.965 - 0.859 Mlig455_044572 {REF} {Length: 766} {RNA1509_2329, RNA1509_2671} {RNA1310_57955.1, RNA1509_2329, RNA1509_2671} {RNA1509_2329, RNA1509_2671, RNA815_25765}
24. MligTC455_15546 141 2.93 Mlig455_021744

Neo: -

Age: -

2.546 0.968 0.808 - 0.770 - - Mlig455_021744 {REF} {Length: 1839} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=60.5]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=26.5]} {Mouse: ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=51.2, Expect=1e-06]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=72.0, Expect=3e-13]} {Celegans: WBGene00020586, frpr-18, FLP-2 receptor; FMRFamide Peptide Receptor family, [Score=69.3, Expect=2e-12]} {Smed: dd_Smed_v6_25364_0_1, dd_Smed_v6_25364_0_1, [RH, Score=197, Expect=7e-59]} {RNA1310_26850} {RNA815_17444}
25. MligTC455_43557 362 7.55 Mlig455_059172, Mlig455_065527

Neo: -

Age: Down-Down-Up

Region-specific R2: 6.284

Region-enriched R2: 5.832/0.00001

ANKRD63 2.545 0.959 0.782 - 0.804 - -

Mlig455_059172 {REF} {Length: 1739} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.2]; Ankyrin repeats (many copies) [PF13637.8, score=42.6]; Ankyrin repeat [PF13606.8, score=27.6]; Ankyrin repeats (many copies) [PF13857.8, score=27.1]; Ankyrin repeat [PF00023.32, score=25.9]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [Score=68.2, Expect=7e-12]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [Score=67.4, Expect=7e-12]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=49.3, Expect=7e-06]} {Celegans: WBGene00011240, R11A8.7, Ankyrin repeat and KH domain-containing protein R11A8.7, [Score=49.3, Expect=4e-06]} {Smed: dd_Smed_v6_10280_0_1, dd_Smed_v6_10280_0_1, [Score=81.3, Expect=1e-16]} {RNA1310_44826} {RNA815_62096}

Mlig455_065527 {REF} {Length: 2998} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=52.3]; Ankyrin repeats (many copies) [PF13637.8, score=42.0]; Ankyrin repeats (many copies) [PF13857.8, score=26.7]; Ankyrin repeat [PF00023.32, score=26.0]; Ankyrin repeat [PF13606.8, score=22.6]} {Human: ENSG00000230778, ANKRD63, ankyrin repeat domain 63, [Score=68.2, Expect=7e-12]} {Mouse: ENSMUSG00000078137, Ankrd63, ankyrin repeat domain 63, [Score=68.2, Expect=6e-12]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=50.1, Expect=5e-06]} {Celegans: WBGene00011240, R11A8.7, Ankyrin repeat and KH domain-containing protein R11A8.7, [Score=50.4, Expect=2e-06]} {Smed: dd_Smed_v6_10280_0_1, dd_Smed_v6_10280_0_1, [Score=80.9, Expect=2e-16]} {RNA1509_30872} {RNA1310_44826} {RNA815_62096}
26. MligTC455_27785 115 2.39 Mlig455_001141

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.796

HMCN2 2.543 0.963 0.794 - 0.786 - - Mlig455_001141 {REF} {Length: 2156} {Pfam: von Willebrand factor type A domain [PF13519.8, score=54.7]; von Willebrand factor type A domain [PF13768.8, score=30.6]} {Human: ENSG00000148357, HMCN2, hemicentin 2, [Score=81.3, Expect=2e-15]} {Mouse: ENSMUSG00000007030, Vwa7, von Willebrand factor A domain containing 7, [Score=79.0, Expect=6e-15]; ENSMUSG00000055632, Hmcn2, hemicentin 2, [Score=77.8, Expect=2e-14]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=96.3, Expect=1e-20]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=79.7, Expect=2e-15]} {RNA1509_38050} {RNA1310_19586} {RNA815_17693}
27. MligTC455_47112 6177 128.69 Mlig455_029072

Neo: -

Age: -

Region-enriched R2: 5.814/0.00000
Region-enriched R3: 4.390/0.00000

Regeneration-downregulated R2: -4.730

Regeneration-depleted R2: -4.730

2.543 - 0.730 - 0.973 - 0.840 Mlig455_029072 {REF} {Length: 748} {RNA1509_2329} {RNA1310_57955.1} {RNA815_25765}
28. MligTC455_11788 20 0.41 Mlig455_043729, Mlig455_043819, Mlig455_047429

Neo: -

Age: -

ANGPTL1 2.531 0.963 - - 0.781 - 0.787

Mlig455_043729 {REF} {Length: 1137} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=144.4]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=131, Expect=2e-34]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=129, Expect=9e-34]; ENSG00000130812, ANGPTL6, angiopoietin like 6, [Score=127, Expect=5e-33]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=134, Expect=9e-36]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=131, Expect=8e-35]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=129, Expect=8e-34]} {Dmel: FBgn0003326, sca, scabrous, [Score=119, Expect=4e-30]} {Celegans: WBGene00017013, ensh-1, [Score=46.6, Expect=1e-05]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=110, Expect=4e-27]} {RNA1509_26827} {RNA1310_41424} {RNA815_48855}

Mlig455_043819 {REF} {Length: 1111} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=143.1]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=129, Expect=1e-33]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=127, Expect=4e-33]; ENSG00000130812, ANGPTL6, angiopoietin like 6, [Score=125, Expect=2e-32]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=132, Expect=5e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=130, Expect=3e-34]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=127, Expect=4e-33]} {Dmel: FBgn0003326, sca, scabrous, [Score=117, Expect=2e-29]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=108, Expect=2e-26]} {RNA1509_26827} {RNA1310_41424} {RNA815_48855}

Mlig455_047429 {REF} {Length: 1072} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=143.1]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=129, Expect=1e-33]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=127, Expect=4e-33]; ENSG00000130812, ANGPTL6, angiopoietin like 6, [Score=125, Expect=2e-32]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=132, Expect=5e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=130, Expect=3e-34]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=127, Expect=4e-33]} {Dmel: FBgn0003326, sca, scabrous, [Score=117, Expect=2e-29]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=108, Expect=2e-26]} {RNA1509_26827} {RNA1310_41424} {RNA815_48855}
29. MligTC455_15332 44 0.93 Mlig455_062622, Mlig455_067527

Neo: -

Age: -

Region-enriched R2: 7.516/0.00418

ASIC4 2.513 0.968 0.793 - - - 0.752

Mlig455_062622 {REF} {Length: 2228} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=73.0]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=47.4, Expect=7e-06]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=51.6, Expect=2e-07]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=55.8, Expect=3e-09]} {Smed: dd_Smed_v6_19727_0_1, dd_Smed_v6_19727_0_1, [Score=53.1, Expect=2e-08]} {RNA1310_17847} {RNA815_27317}

Mlig455_067527 {REF} {Length: 1916} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=147.3]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=50.1, Expect=1e-05]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=50.8, Expect=3e-06]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=54.7, Expect=1e-07]} {Smed: dd_Smed_v6_19727_0_1, dd_Smed_v6_19727_0_1, [Score=53.5, Expect=2e-07]} {RNA1310_17847} {RNA815_27317}
30. MligTC455_35446 75 1.56 Mlig455_031433

Neo: -

Age: Down-Up-Up

2.512 0.970 0.716 - 0.826 - - Mlig455_031433 {REF} {Length: 1430} {NoTransDecoderORF} {RNA1310_35373} {RNA815_22739}
31. MligTC455_20529 56 1.18 Mlig455_005302

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.700

2.509 0.963 0.767 - 0.779 - - Mlig455_005302 {REF} {Length: 1691} {RNA1509_3030} {RNA1310_35103} {RNA815_26539}
32. MligTC455_24952 637 13.28 Mlig455_054178, Mlig455_060727

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.165

Region-enriched R2: 3.160/0.00003

Regeneration-downregulated BL: -4.774

Regeneration-depleted BL: -4.774

CCDC169 2.506 0.957 0.787 - 0.762 - -

Mlig455_054178 {REF} {Length: 1390} {Pfam: Domain of unknown function (DUF4600) [PF15372.8, score=97.2]} {Human: ENSG00000242715, CCDC169, coiled-coil domain containing 169, [RH, Score=82.8, Expect=6e-19]} {Mouse: ENSMUSG00000048655, Ccdc169, coiled-coil domain containing 169, [RH, Score=94.0, Expect=3e-23]} {Smed: dd_Smed_v6_12011_0_1, dd_Smed_v6_12011_0_1, [RH, Score=207, Expect=9e-68]} {RNA1509_8270} {RNA1310_23029} {RNA815_11545}

Mlig455_060727 {REF} {Length: 1391} {Pfam: Domain of unknown function (DUF4600) [PF15372.8, score=97.2]} {Human: ENSG00000242715, CCDC169, coiled-coil domain containing 169, [RH, Score=82.8, Expect=6e-19]} {Mouse: ENSMUSG00000048655, Ccdc169, coiled-coil domain containing 169, [RH, Score=94.0, Expect=3e-23]} {Smed: dd_Smed_v6_12011_0_1, dd_Smed_v6_12011_0_1, [RH, Score=207, Expect=9e-68]} {RNA1509_8270} {RNA1310_23029, RNA1509_8270} {RNA1509_8270, RNA815_11545}
33. MligTC455_35880 96 2 Mlig455_050765

Neo: -

Age: -

Region-enriched R4: 3.806/0.02203

2.502 0.792 - 0.958 - - 0.752 Mlig455_050765 {REF} {Length: 848} {NoTransDecoderORF} {RNA1509_20101} {RNA1310_53086.1} {RNA815_22311}
34. MligTC455_16199 114 2.37 Mlig455_041013, Mlig455_041178

Neo: Irradiation

Age: -

Region-enriched R2: 9.007/0.00037

2.498 0.962 0.739 - 0.797 - -

Mlig455_041013 {REF} {Length: 3381} {RNA1509_42904} {RNA1310_20434} {RNA815_22064}

Mlig455_041178 {REF} {Length: 2722} {RNA1509_42904} {RNA1310_20004} {RNA815_22064}
35. MligTC455_19795 50 1.05 Mlig455_015163, Mlig455_015285

Neo: -

Age: Up-Down-Down

2.467 - 0.732 - 0.781 - 0.954

Mlig455_015163 {REF} {Length: 4537} {TRANSSPLICED} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=183.2]} {Smed: dd_Smed_v6_23771_0_1, dd_Smed_v6_23771_0_1, [RH, Score=366, Expect=7e-119]} {RNA1509_44797} {RNA1310_13221} {RNA815_45407}

Mlig455_015285 {REF} {Length: 4094} {TRANSSPLICED} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=183.3]} {Smed: dd_Smed_v6_23771_0_1, dd_Smed_v6_23771_0_1, [RH, Score=366, Expect=9e-119]} {RNA1509_57431} {RNA1310_13221} {RNA815_45407}
36. MligTC455_20532 63 1.32 Mlig455_029971

Neo: -

Age: -

2.46 0.963 - - 0.747 - 0.750 Mlig455_029971 {REF} {Length: 1702} {Pfam: UPF0489 domain [PF12640.9, score=20.3]} {RNA1509_3030} {RNA1310_35103} {RNA815_26539}
37. MligTC455_45597 116 2.41 Mlig455_049417

Neo: -

Age: Down-Up-Up

Region-enriched R2: 5.185/0.02405

2.419 0.954 0.747 - 0.718 - - Mlig455_049417 {REF} {Length: 1106} {RNA1310_45744} {RNA815_56662}
38. MligTC455_31463 20 0.42 Mlig455_057169

Neo: -

Age: -

1.909 0.963 - - 0.946 - - Mlig455_057169 {REF} {Length: 1647} {Pfam: Methyltransferase FkbM domain [PF05050.14, score=39.0]} {Smed: dd_Smed_v6_12148_0_2, dd_Smed_v6_12148_0_2, [Score=82.4, Expect=3e-18]} {RNA1509_6604} {RNA1310_43619} {RNA815_6128.2}
39. MligTC455_49470 54 1.13 Mlig455_054252

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.395

Region-enriched R3: 5.217/0.00090

B3GNT5 1.9 - - - 0.970 - 0.930 Mlig455_054252 {REF} {Length: 3081} {Pfam: Galactosyltransferase [PF01762.23, score=90.8]} {Human: ENSG00000176597, B3GNT5, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5, [Score=99.4, Expect=6e-22]} {Mouse: ENSMUSG00000034780, B3galt1, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1, [Score=89.0, Expect=6e-19]} {Dmel: FBgn0000221, brn, brainiac, [Score=77.4, Expect=3e-15]} {Celegans: WBGene00044630, bus-17, Hexosyltransferase, [RH, Score=65.5, Expect=2e-11]} {Smed: dd_Smed_v6_13702_0_1, dd_Smed_v6_13702_0_1, [RH, Score=170, Expect=1e-47]} {RNA1509_54587} {RNA1310_18654} {RNA815_8083}
40. MligTC455_49469 65 1.35 Mlig455_016236

Neo: -

Age: -

Region-enriched R3: 5.774/0.00000

B3GNT5 1.89 - - - 0.955 - 0.935 Mlig455_016236 {REF} {Length: 2696} {Pfam: Galactosyltransferase [PF01762.23, score=91.0]} {Human: ENSG00000176597, B3GNT5, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5, [Score=100, Expect=1e-22]} {Mouse: ENSMUSG00000034780, B3galt1, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1, [Score=86.3, Expect=3e-18]; ENSMUSG00000043300, B3galnt1, UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1, [Score=83.2, Expect=4e-17]} {Dmel: FBgn0000221, brn, brainiac, [Score=77.0, Expect=3e-15]} {Celegans: WBGene00044630, bus-17, Hexosyltransferase, [RH, Score=65.5, Expect=2e-11]} {Smed: dd_Smed_v6_13702_0_1, dd_Smed_v6_13702_0_1, [RH, Score=171, Expect=5e-49]} {RNA1509_54587, RNA1509_56943} {RNA1310_18654, RNA1509_54587, RNA1509_56943} {RNA1509_54587, RNA1509_56943, RNA815_8083}
41. MligTC455_27186 28 0.57 Mlig455_010236

Neo: -

Age: logFC(26M/2M)=-1.855

1.889 0.963 - - 0.926 - - Mlig455_010236 {REF} {Length: 486} {RNA1509_7146} {RNA1310_76234.2} {RNA815_34947.2}
42. MligTC455_32422 37 0.78 Mlig455_031348

Neo: -

Age: -

CHRNA6 1.875 0.956 - - 0.919 - - Mlig455_031348 {REF} {Length: 1659} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=69.7]} {Human: ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=61.6, Expect=5e-10]; ENSG00000160716, CHRNB2, cholinergic receptor nicotinic beta 2 subunit, [Score=61.2, Expect=8e-10]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=61.2, Expect=5e-10]; ENSMUSG00000027950, Chrnb2, cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal), [Score=60.8, Expect=8e-10]; ENSMUSG00000055026, Gabrg3, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3, [Score=58.5, Expect=4e-09]} {Dmel: FBgn0000038, nAChRbeta1, nicotinic Acetylcholine Receptor beta1, [Score=48.5, Expect=4e-06]} {Celegans: WBGene00000057, acr-18, AcetylCholine Receptor; Acetylcholine receptor, one of nine alpha a7-like nicotinic acetylcholine receptor subunits (58.6 kD) (Acr-18), [Score=63.5, Expect=5e-11]} {Smed: dd_Smed_v6_30253_0_1, dd_Smed_v6_30253_0_1, [Score=59.3, Expect=6e-10]} {RNA1310_61084} {RNA815_48984}
43. MligTC455_44998 385 8.02 Mlig455_041387

Neo: -

Age: logFC(26M/2M)=-0.278

Region-enriched R3: 5.457/0.00000
Region-enriched R2: 4.938/0.00139

FZD4 1.839 - - - 0.966 - 0.873 Mlig455_041387 {REF} {Length: 3889} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=311.1]; Fz domain [PF01392.24, score=97.0]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [Score=416, Expect=2e-138]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [Score=414, Expect=4e-138]} {Dmel: FBgn0001085, fz, frizzled, [Score=284, Expect=2e-87]} {Celegans: WBGene00003006, lin-17, Transmembrane receptor LIN-17, [RH, Score=263, Expect=9e-80]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [Score=435, Expect=8e-146]} {RNA1509_26315} {RNA1310_7806, RNA1509_26315} {RNA1509_26315, RNA815_21086}
44. MligTC455_48320 81 1.69 Mlig455_008829

Neo: -

Age: Down-Down-Up

TOB1 1.829 - - - 0.872 - 0.957 Mlig455_008829 {REF} {Length: 832} {Pfam: BTG family [PF07742.14, score=62.3]} {Human: ENSG00000141232, TOB1, transducer of ERBB2, 1, [Score=64.7, Expect=2e-12]} {Mouse: ENSMUSG00000037573, Tob1, transducer of ErbB-2.1, [Score=63.2, Expect=4e-12]} {Dmel: FBgn0028397, Tob, [Score=68.6, Expect=5e-14]} {Smed: dd_Smed_v6_7444_0_1, dd_Smed_v6_7444_0_1, [Score=75.1, Expect=5e-17]} {RNA1509_42403, RNA1509_59615} {RNA1310_49803, RNA1509_42403, RNA1509_59615}
45. MligTC455_18541 1108 23.09 Mlig455_003326

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.290

Region-enriched R2: 4.433/0.00000
Region-enriched R3: 3.875/0.00000

SFRP2 1.811 - 0.840 - - - 0.971 Mlig455_003326 {REF} {Length: 2658} {TRANSSPLICED} {Pfam: Fz domain [PF01392.24, score=86.0]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [RH, Score=167, Expect=4e-46]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [RH, Score=165, Expect=2e-45]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=101, Expect=8e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=1e-44]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [RH, Score=157, Expect=1e-42]} {RNA1509_5709} {RNA1310_15264} {RNA815_7067}
46. MligTC455_32217 159 3.31 Mlig455_028331, Mlig455_066154, Mlig455_066180

Neo: -

Age: -

1.799 0.959 - - 0.840 - -

Mlig455_028331 {REF} {Length: 1503} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=39.8]} {Smed: dd_Smed_v6_31564_0_1, dd_Smed_v6_31564_0_1, [Score=53.5, Expect=1e-08]} {RNA1509_23615} {RNA1310_49081} {RNA815_24982.1}

Mlig455_066154 {REF} {Length: 1501} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=42.3]} {Smed: dd_Smed_v6_31564_0_1, dd_Smed_v6_31564_0_1, [Score=79.3, Expect=2e-16]} {RNA1509_23615} {RNA1310_49081} {RNA815_24982.1}

Mlig455_066180 {REF} {Length: 1298} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=41.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=21.2]} {Smed: dd_Smed_v6_31564_0_1, dd_Smed_v6_31564_0_1, [Score=78.2, Expect=8e-16]} {RNA1509_23615} {RNA1310_49081} {RNA815_12536.1}
47. MligTC455_15134 15 0.31 Mlig455_000804

Neo: -

Age: -

CNGA3 1.792 0.963 - - 0.829 - - Mlig455_000804 {REF} {Length: 2294} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=62.8]; Ion transport protein [PF00520.33, score=39.4]} {Human: ENSG00000144191, CNGA3, cyclic nucleotide gated channel alpha 3, [Score=351, Expect=2e-113]; ENSG00000198515, CNGA1, cyclic nucleotide gated channel alpha 1, [Score=344, Expect=2e-110]; ENSG00000183862, CNGA2, cyclic nucleotide gated channel alpha 2, [Score=340, Expect=2e-109]} {Mouse: ENSMUSG00000026114, Cnga3, cyclic nucleotide gated channel alpha 3, [Score=352, Expect=9e-115]; ENSMUSG00000067220, Cnga1, cyclic nucleotide gated channel alpha 1, [Score=342, Expect=7e-110]; ENSMUSG00000005864, Cnga2, cyclic nucleotide gated channel alpha 2, [Score=338, Expect=9e-109]} {Dmel: FBgn0259145, CG42260, [Score=463, Expect=1e-153]} {Celegans: WBGene00006526, tax-4, Cyclic nucleotide-gated cation channel, [Score=281, Expect=1e-86]} {Smed: dd_Smed_v6_22398_0_1, dd_Smed_v6_22398_0_1, [Score=343, Expect=2e-111]} {RNA1310_120793} {RNA815_25814}
48. MligTC455_36020 1311 27.3 Mlig455_018390

Neo: -

Age: Down-Down-Up

Region-enriched R3: 5.222/0.00000
Region-enriched R2: 4.515/0.00230

1.788 - - - 0.986 - 0.802 Mlig455_018390 {REF} {Length: 1439} {RNA1509_748} {RNA1310_90094, RNA1509_748} {RNA1509_748, RNA815_23687}
49. MligTC455_42647 262 5.45 Mlig455_044411

Neo: -

Age: -

Region-enriched R2: 3.002/0.01555
Region-enriched R3: 2.321/0.04628

MEIS1 1.786 0.957 - - 0.829 - - Mlig455_044411 {REF} {Length: 3872} {Pfam: N-terminal of Homeobox Meis and PKNOX1 [PF16493.7, score=134.9]; Homeobox KN domain [PF05920.13, score=71.0]; Homeodomain [PF00046.31, score=32.6]} {Human: ENSG00000143995, MEIS1, Meis homeobox 1, [RH, Score=190, Expect=5e-53]; ENSG00000134138, MEIS2, Meis homeobox 2, [RH, Score=190, Expect=5e-53]} {Mouse: ENSMUSG00000020160, Meis1, Meis homeobox 1, [RH, Score=190, Expect=3e-53]; ENSMUSG00000027210, Meis2, Meis homeobox 2, [RH, Score=190, Expect=4e-53]} {Dmel: FBgn0001235, hth, homothorax, [Score=176, Expect=2e-50]} {Celegans: WBGene00006796, unc-62, Homeobox protein unc-62, [RH, Score=170, Expect=1e-45]} {Smed: dd_Smed_v6_6114_0_2, dd_Smed_v6_6114_0_2, [RH, Score=226, Expect=8e-66]} {RNA1509_22853} {RNA1310_27014} {RNA815_28484}
50. MligTC455_21467 816 17 Mlig455_058500, Mlig455_058506

Neo: -

Age: Down-Up-Down

Region-enriched R3: 4.231/0.00018
Region-enriched R2: 3.825/0.00867

1.785 - - - 0.831 - 0.954

Mlig455_058500 {REF} {Length: 466} {RNA1509_55725} {RNA1310_68398} {RNA815_42823}

Mlig455_058506 {REF} {Length: 760} {RNA1509_55725} {RNA1310_68398, RNA1509_55725} {RNA1509_55725, RNA815_49141}
51. MligTC455_40051 36 0.76 Mlig455_025990

Neo: -

Age: logFC(26M/2M)=-0.633

PRKCE 1.781 0.971 0.810 - - - - Mlig455_025990 {REF} {Length: 2622} {Pfam: Protein kinase domain [PF00069.27, score=102.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=69.5]; Kinase-like [PF14531.8, score=19.5]} {Human: ENSG00000171132, PRKCE, protein kinase C epsilon, [Score=84.3, Expect=1e-16]} {Mouse: ENSMUSG00000045038, Prkce, protein kinase C, epsilon, [Score=82.0, Expect=5e-16]} {Dmel: FBgn0283472, S6k, Ribosomal protein S6 kinase, [Score=79.0, Expect=2e-15]} {Celegans: WBGene00009793, pkn-1, Protein Kinase N (PKN) homolog, [Score=73.2, Expect=2e-13]} {Smed: dd_Smed_v6_8010_0_1, dd_Smed_v6_8010_0_1, [Score=77.8, Expect=4e-15]} {RNA1509_36146} {RNA1310_24732} {RNA815_64704}
52. MligTC455_50927 254 5.29 Mlig455_070541, Mlig455_070562

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.296

Region-enriched R2: 7.883/0.00008
Region-enriched R3: 4.441/0.03979

FZD4 1.78 0.954 0.826 - - - -

Mlig455_070541 {REF} {Length: 3522} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=471, Expect=6e-159]} {RNA1509_15834} {RNA1310_3800, RNA1509_15834} {RNA1509_15834, RNA815_19571}

Mlig455_070562 {REF} {Length: 3527} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=2e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=470, Expect=8e-159]} {RNA1509_15834} {RNA1310_3800} {RNA815_19571}
53. MligTC455_50822 17 0.35 Mlig455_052415

Neo: -

Age: -

1.776 - - - 0.967 - 0.809 Mlig455_052415 {REF} {Length: 1753} {Pfam: Major Facilitator Superfamily [PF07690.18, score=80.5]} {Celegans: WBGene00017369, F10G7.5, [Score=108, Expect=2e-25]} {Smed: dd_Smed_v6_5351_0_2, dd_Smed_v6_5351_0_2, [Score=183, Expect=5e-52]} {RNA1509_43398} {RNA1310_11789.1} {RNA815_4854}
54. MligTC455_36693 11 0.24 Mlig455_061780

Neo: -

Age: -

CHRNA7 1.775 - - - 0.825 0.950 - Mlig455_061780 {REF} {Length: 2331} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=190.0]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=87.0]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=217, Expect=1e-64]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=217, Expect=5e-64]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=217, Expect=5e-64]; ENSG00000166664, CHRFAM7A, CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion, [Score=216, Expect=7e-66]; ENSG00000275917, CHRFAM7A, CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion, [Score=214, Expect=8e-65]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=194, Expect=9e-56]} {Dmel: FBgn0032151, nAChRalpha6, nicotinic Acetylcholine Receptor alpha6, [Score=286, Expect=2e-90]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=195, Expect=7e-56]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=233, Expect=3e-70]} {RNA1509_7221} {RNA1310_66513} {RNA815_31560}
55. MligTC455_32554 51 1.07 Mlig455_024179

Neo: -

Age: -

1.764 0.972 0.792 - - - - Mlig455_024179 {REF} {Length: 926} {RNA1509_24504} {RNA1310_3168} {RNA815_18309}
56. MligTC455_36021 6487 135.15 Mlig455_069510

Neo: -

Age: Down-Down-Up

Region-enriched R3: 6.241/0.00000
Region-enriched R2: 5.640/0.00000

1.763 - - - 0.960 - 0.803 Mlig455_069510 {REF} {Length: 894} {Smed: dd_Smed_v6_10163_0_1, dd_Smed_v6_10163_0_1, [Score=49.7, Expect=3e-07]} {RNA1509_748} {RNA1310_90094} {RNA815_23687}
57. MligTC455_18470 514 10.71 Mlig455_043915

Neo: -

Age: -

1.759 - 0.809 - 0.950 - - Mlig455_043915 {REF} {Length: 1376} {RNA1509_15794, RNA1509_31295, RNA1509_46879, RNA1509_48240} {RNA1310_29921.1, RNA1509_15794, RNA1509_31295, RNA1509_46879, RNA1509_48240} {RNA1509_15794, RNA1509_31295, RNA1509_46879, RNA1509_48240, RNA815_24315}
58. MligTC455_14519 25 0.51 Mlig455_005304

Neo: -

Age: -

1.753 0.963 - - 0.790 - - Mlig455_005304 {REF} {Length: 1686} {RNA1509_3030} {RNA1310_65512} {RNA815_48423}
59. MligTC455_15726 270 5.63 Mlig455_031204

Neo: -

Age: -

Region-enriched R2: 6.820/0.00015

ADAMTS18 1.748 0.966 0.782 - - - - Mlig455_031204 {REF} {Length: 2405} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=77.6]; Metallo-peptidase family M12 [PF13688.8, score=52.5]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=45.6]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=41.4]; ADAM cysteine-rich domain [PF17771.3, score=40.0]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=30.9]; Astacin (Peptidase family M12A) [PF01400.26, score=19.3]} {Human: ENSG00000140873, ADAMTS18, ADAM metallopeptidase with thrombospondin type 1 motif 18, [Score=90.9, Expect=1e-18]} {Mouse: ENSMUSG00000049538, Adamts16, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16, [Score=90.1, Expect=1e-18]; ENSMUSG00000053399, Adamts18, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18, [Score=89.7, Expect=2e-18]} {Dmel: FBgn0034903, sona, sol narae, [RH, Score=114, Expect=7e-27]} {Celegans: WBGene00003248, mig-17, ADAM family mig-17, [RH, Score=100, Expect=2e-22]} {RNA1509_42775} {RNA1310_19585.1, RNA1509_42775} {RNA1509_42775, RNA815_17997}
60. MligTC455_23202 2035 42.39 Mlig455_049148, Mlig455_049198

Neo: -

Age: Down-Down-Up

Region-enriched R3: 7.168/0.00000
Region-enriched R2: 4.894/0.01000

1.748 - - - 0.999 - 0.749

Mlig455_049148 {REF} {Length: 686} {Pfam: CUB domain [PF00431.22, score=29.6]} {Celegans: WBGene00008596, clec-54, C-type LECtin, [Score=44.3, Expect=1e-05]} {RNA1509_15319, RNA1509_26181} {RNA1310_56206, RNA1509_15319, RNA1509_26181} {RNA1509_15319, RNA1509_26181, RNA815_28296}

Mlig455_049198 {REF} {Length: 687} {Pfam: CUB domain [PF00431.22, score=29.3]} {Celegans: WBGene00008596, clec-54, C-type LECtin, [Score=44.3, Expect=1e-05]} {RNA1509_29109} {RNA1310_56206, RNA1509_29109} {RNA1509_29109, RNA815_28296}
61. MligTC455_01421 9 0.2 Mlig455_020111

Neo: -

Age: -

1.744 0.963 - - 0.781 - - Mlig455_020111 {REF} {Length: 880} {Pfam: WSC domain [PF01822.21, score=53.2]; PAN domain [PF00024.28, score=20.6]} {RNA1509_53783} {RNA1310_34968.1} {RNA815_9084.1}
62. MligTC455_08342 11 0.24 Mlig455_069886

Neo: -

Age: -

1.744 0.963 - - 0.781 - - Mlig455_069886 {REF} {Length: 980} {Pfam: WSC domain [PF01822.21, score=48.3]; PAN domain [PF00024.28, score=22.0]} {RNA1509_53783} {RNA1310_34968.1} {RNA815_24434}
63. MligTC455_20900 185 3.85 Mlig455_016663, Mlig455_056352, Mlig455_056364

Neo: -

Age: logFC(26M/2M)=0.440

Region-enriched R3: 6.081/0.00000
Region-enriched R2: 5.467/0.00097

PTF1A 1.733 - - - 0.765 - 0.968

Mlig455_016663 {REF} {Length: 1779} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=69.4]} {Human: ENSG00000168267, PTF1A, pancreas associated transcription factor 1a, [RH, Score=114, Expect=2e-28]} {Mouse: ENSMUSG00000026735, Ptf1a, pancreas specific transcription factor, 1a, [RH, Score=112, Expect=5e-28]} {Dmel: FBgn0037475, Fer1, 48 related 1, [RH, Score=123, Expect=1e-32]} {Celegans: WBGene00001957, hlh-13, Helix-loop-helix protein 13, [Score=86.7, Expect=2e-20]} {Smed: dd_Smed_v6_13704_0_1, dd_Smed_v6_13704_0_1, [RH, Score=126, Expect=2e-34]} {RNA1310_22164} {RNA815_43429}

Mlig455_056352 {REF} {Length: 1831} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=69.3]} {Human: ENSG00000168267, PTF1A, pancreas associated transcription factor 1a, [RH, Score=114, Expect=3e-28]} {Mouse: ENSMUSG00000026735, Ptf1a, pancreas specific transcription factor, 1a, [RH, Score=112, Expect=6e-28]} {Dmel: FBgn0037475, Fer1, 48 related 1, [RH, Score=123, Expect=1e-32]} {Celegans: WBGene00001957, hlh-13, Helix-loop-helix protein 13, [Score=86.7, Expect=2e-20]} {Smed: dd_Smed_v6_13704_0_1, dd_Smed_v6_13704_0_1, [RH, Score=126, Expect=3e-34]} {RNA1310_22164} {RNA815_43429}

Mlig455_056364 {REF} {Length: 1756} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=69.3]} {Human: ENSG00000168267, PTF1A, pancreas associated transcription factor 1a, [RH, Score=114, Expect=3e-28]} {Mouse: ENSMUSG00000026735, Ptf1a, pancreas specific transcription factor, 1a, [RH, Score=112, Expect=5e-28]} {Dmel: FBgn0037475, Fer1, 48 related 1, [RH, Score=124, Expect=7e-33]} {Celegans: WBGene00001957, hlh-13, Helix-loop-helix protein 13, [Score=86.7, Expect=2e-20]} {Smed: dd_Smed_v6_13704_0_1, dd_Smed_v6_13704_0_1, [RH, Score=126, Expect=3e-34]} {RNA1310_22164} {RNA815_43429}
64. MligTC455_16311 89 1.86 Mlig455_053827, Mlig455_068518

Neo: -

Age: -

Region-enriched R2: 5.249/0.01530

CALML3 1.731 0.955 0.776 - - - -

Mlig455_053827 {REF} {Length: 1659} {Pfam: EF-hand domain pair [PF13499.8, score=64.3]; EF hand [PF00036.34, score=58.1]; EF-hand domain [PF13405.8, score=55.1]; EF hand [PF13202.8, score=37.9]; EF-hand domain pair [PF13833.8, score=32.8]; EF-hand domain [PF14658.8, score=20.4]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=96.7, Expect=3e-25]; ENSG00000143933, CALM2, calmodulin 2, [Score=96.7, Expect=6e-25]; ENSG00000198668, CALM1, calmodulin 1, [Score=96.3, Expect=3e-25]; ENSG00000160014, CALM3, calmodulin 3, [Score=96.3, Expect=3e-25]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=96.3, Expect=2e-25]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=96.3, Expect=2e-25]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=96.3, Expect=2e-25]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=95.9, Expect=2e-25]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=97.1, Expect=7e-26]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=97.4, Expect=5e-26]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=97.4, Expect=4e-26]} {RNA1509_37850} {RNA1310_5623.1} {RNA815_35579}

Mlig455_068518 {REF} {Length: 1007} {Pfam: EF-hand domain pair [PF13499.8, score=64.3]; EF hand [PF00036.34, score=58.1]; EF-hand domain [PF13405.8, score=55.1]; EF hand [PF13202.8, score=38.0]; EF-hand domain pair [PF13833.8, score=33.0]; EF-hand domain [PF14658.8, score=20.4]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=96.7, Expect=2e-25]; ENSG00000143933, CALM2, calmodulin 2, [Score=96.7, Expect=6e-25]; ENSG00000160014, CALM3, calmodulin 3, [Score=96.3, Expect=3e-25]; ENSG00000198668, CALM1, calmodulin 1, [Score=96.3, Expect=3e-25]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=96.3, Expect=2e-25]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=96.3, Expect=2e-25]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=96.3, Expect=2e-25]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=95.9, Expect=3e-25]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=97.1, Expect=7e-26]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=97.1, Expect=5e-26]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=97.1, Expect=4e-26]} {RNA1509_37850} {RNA1310_5623.1} {RNA815_35579}
65. MligTC455_12894 84 1.75 Mlig455_024418, Mlig455_024572

Neo: -

Age: -

Region-enriched R2: 5.211/0.02671

SLC46A2 1.728 0.963 - - 0.765 - -

Mlig455_024418 {REF} {Length: 2094} {Pfam: Major Facilitator Superfamily [PF07690.18, score=30.9]} {Human: ENSG00000119457, SLC46A2, solute carrier family 46 member 2, [Score=72.4, Expect=2e-13]} {Mouse: ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [Score=55.1, Expect=5e-08]} {Dmel: FBgn0030576, CG15890, [Score=68.9, Expect=1e-12]} {Celegans: WBGene00012811, Y43F8A.5, [Score=65.9, Expect=9e-12]} {Smed: dd_Smed_v6_10822_0_1, dd_Smed_v6_10822_0_1, [Score=187, Expect=2e-55]} {RNA1509_40290} {RNA1310_44254} {RNA815_43004}

Mlig455_024572 {REF} {Length: 1344} {Pfam: Major Facilitator Superfamily [PF07690.18, score=30.9]} {Human: ENSG00000119457, SLC46A2, solute carrier family 46 member 2, [Score=72.4, Expect=2e-13]} {Mouse: ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [Score=55.1, Expect=5e-08]} {Dmel: FBgn0030576, CG15890, [Score=68.9, Expect=1e-12]} {Celegans: WBGene00012811, Y43F8A.5, [Score=65.9, Expect=9e-12]} {Smed: dd_Smed_v6_10822_0_1, dd_Smed_v6_10822_0_1, [Score=187, Expect=2e-55]} {RNA1509_40290} {RNA1310_71457} {RNA815_15082}
66. MligTC455_54202 381 7.94 Mlig455_006349

Neo: -

Age: logFC(26M/2M)=0.343

Region-specific R2: 5.916

Region-enriched R2: 5.229/0.00037

MYH6 1.727 0.956 0.771 - - - - Mlig455_006349 {REF} {Length: 6943} {Pfam: Myosin head (motor domain) [PF00063.23, score=929.0]; Myosin tail [PF01576.21, score=591.7]; Myosin N-terminal SH3-like domain [PF02736.21, score=60.7]; Crescentin protein [PF19220.2, score=26.4]; Autophagy protein 16 (ATG16) [PF08614.13, score=20.3]; Macoilin family [PF09726.11, score=18.3]} {Human: ENSG00000197616, MYH6, myosin heavy chain 6, [RH, Score=2075, Expect=0.0]; ENSG00000092054, MYH7, myosin heavy chain 7, [RH, Score=2066, Expect=0.0]; ENSG00000125414, MYH2, myosin heavy chain 2, [RH, Score=2021, Expect=0.0]; ENSG00000109061, MYH1, myosin heavy chain 1, [RH, Score=2013, Expect=0.0]; ENSG00000133020, MYH8, myosin heavy chain 8, [RH, Score=2007, Expect=0.0]; ENSG00000264424, MYH4, myosin heavy chain 4, [RH, Score=1993, Expect=0.0]; ENSG00000109063, MYH3, myosin heavy chain 3, [RH, Score=1974, Expect=0.0]} {Mouse: ENSMUSG00000040752, Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, [RH, Score=2076, Expect=0.0]; ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [RH, Score=2063, Expect=0.0]; ENSMUSG00000057003, Myh4, myosin, heavy polypeptide 4, skeletal muscle, [RH, Score=2041, Expect=0.0]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [RH, Score=2018, Expect=0.0]; ENSMUSG00000055775, Myh8, myosin, heavy polypeptide 8, skeletal muscle, perinatal, [RH, Score=2015, Expect=0.0]; ENSMUSG00000033196, Myh2, myosin, heavy polypeptide 2, skeletal muscle, adult, [RH, Score=2009, Expect=0.0]; ENSMUSG00000020908, Myh3, myosin, heavy polypeptide 3, skeletal muscle, embryonic, [RH, Score=1981, Expect=0.0]; ENSMUSG00000060180, Myh13, myosin, heavy polypeptide 13, skeletal muscle, [RH, Score=1979, Expect=0.0]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [RH, Score=2100, Expect=0.0]} {Celegans: WBGene00019064, myo-5, MYOsin heavy chain structural genes, [RH, Score=1996, Expect=0.0]} {Smed: dd_Smed_v6_579_0_1, dd_Smed_v6_579_0_1, [RH, Score=2705, Expect=0.0]} {RNA1509_16048, RNA1509_54239, RNA1509_55838} {RNA1310_1388, RNA1509_16048, RNA1509_54239, RNA1509_55838} {RNA1509_16048, RNA1509_54239, RNA1509_55838, RNA815_129.1}
67. MligTC455_27187 3569 74.36 Mlig455_010139, Mlig455_010238

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-2.816

Region-enriched R3: 7.270/0.00000
Region-enriched R2: 5.462/0.00180

1.717 - - - 0.968 - 0.749

Mlig455_010139 {REF} {Length: 1000} {RNA1509_37487} {RNA1310_97543.1} {RNA815_20558}

Mlig455_010238 {REF} {Length: 763} {RNA1509_37487} {RNA1310_97543.1} {RNA815_20558}
68. MligTC455_53936 24 0.5 Mlig455_021898

Neo: -

Age: -

1.716 0.955 0.761 - - - - Mlig455_021898 {REF} {Length: 737} {NoTransDecoderORF} {RNA1310_130902}
69. MligTC455_26653 3263 67.97 Mlig455_049144, Mlig455_049196

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.518

Region-specific R3: 7.699

Region-enriched R3: 6.693/0.00000
Region-enriched R2: 4.831/0.00028

1.711 - - - 0.957 - 0.754

Mlig455_049144 {REF} {Length: 862} {Pfam: CUB domain [PF00431.22, score=21.5]} {RNA1509_5316} {RNA1310_45244} {RNA815_23025}

Mlig455_049196 {REF} {Length: 3464} {Pfam: CUB domain [PF00431.22, score=21.5]} {RNA1509_23994, RNA1509_5316} {RNA1310_45244, RNA1509_23994, RNA1509_5316} {RNA1509_23994, RNA1509_5316, RNA815_23025}
70. MligTC455_27144 3959 82.47 Mlig455_010234

Neo: -

Age: logFC(26M/2M)=-2.003

Region-enriched R3: 6.983/0.00000
Region-enriched R2: 5.555/0.00267

1.71 - - - 0.969 - 0.741 Mlig455_010234 {REF} {Length: 439} {RNA1509_34122, RNA1509_54249, RNA1509_5614} {RNA1310_56673, RNA1509_34122, RNA1509_54249, RNA1509_5614} {RNA1509_34122, RNA1509_54249, RNA1509_5614, RNA815_23606.1}
71. MligTC455_19758 53 1.1 Mlig455_002464

Neo: -

Age: -

Region-enriched R2: 6.578/0.02863

1.708 0.964 - - 0.744 - - Mlig455_002464 {REF} {Length: 2549} {RNA1310_38437} {RNA815_40458}
72. MligTC455_27147 3478 72.45 Mlig455_010133

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.490

Region-enriched R3: 5.885/0.00000
Region-enriched R2: 4.733/0.00253

1.704 - - - 0.954 - 0.750 Mlig455_010133 {REF} {Length: 571} {RNA1509_1301, RNA1509_1962, RNA1509_47216, RNA1509_6478} {RNA1310_108580, RNA1509_1301, RNA1509_1962, RNA1509_47216, RNA1509_6478} {RNA1509_1301, RNA1509_1962, RNA1509_47216, RNA1509_6478, RNA815_7257.5}
73. MligTC455_33936 62 1.29 Mlig455_061181

Neo: -

Age: Down-Down-Up

Region-enriched R3: 4.766/0.00000

1.704 - - - - 0.748 0.956 Mlig455_061181 {REF} {Length: 2443} {Pfam: Fibronectin type II domain [PF00040.21, score=54.5]} {Mouse: ENSMUSG00000054580, Pla2r1, phospholipase A2 receptor 1, [Score=50.1, Expect=2e-06]} {RNA1310_23349.1} {RNA815_44226.1}
74. MligTC455_19911 3456 72.01 Mlig455_010146

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.657

Region-enriched R3: 6.134/0.00000
Region-enriched R2: 5.918/0.00015

1.696 - - - 0.959 - 0.737 Mlig455_010146 {REF} {Length: 497} {RNA1509_40525} {RNA1310_91403} {RNA815_34947.3}
75. MligTC455_23101 397 8.28 Mlig455_048080

Neo: -

Age: -

Region-enriched R2: 3.122/0.00807

1.695 0.954 - - 0.741 - - Mlig455_048080 {REF} {Length: 721} {TRANSSPLICED} {RNA1509_16955} {RNA1310_49452, RNA1509_16955} {RNA1509_16955, RNA815_4585}
76. MligTC455_38972 202 4.21 Mlig455_002639, Mlig455_011248, Mlig455_047800

Neo: -

Age: -

1.681 0.969 - 0.712 - - -

Mlig455_002639 {REF} {Length: 229} {NoTransDecoderORF} {RNA1509_32404} {RNA1310_56058} {RNA815_36932.1}

Mlig455_011248 {REF} {Length: 200} {NoTransDecoderORF} {RNA1509_32404} {RNA1310_54013.2} {RNA815_36932.1}

Mlig455_047800 {REF} {Length: 1142} {NoTransDecoderORF} {RNA1509_32404} {RNA1310_57981} {RNA815_36932.1}
77. MligTC455_43193 359 7.49 Mlig455_033211

Neo: -

Age: -

1.676 0.961 - - - - 0.715 Mlig455_033211 {REF} {Length: 280} {NoTransDecoderORF} {RNA1310_121983}
78. MligTC455_09126 12 0.25 Mlig455_051248

Neo: -

Age: Up-Down-Down

TBX2 1.674 - - - 0.962 - 0.712 Mlig455_051248 {REF} {Length: 2894} {Pfam: T-box [PF00907.24, score=269.9]} {Human: ENSG00000121068, TBX2, T-box 2, [RH, Score=364, Expect=3e-116]; ENSG00000135111, TBX3, T-box 3, [RH, Score=356, Expect=6e-113]} {Mouse: ENSMUSG00000018604, Tbx3, T-box 3, [RH, Score=365, Expect=1e-116]; ENSMUSG00000000093, Tbx2, T-box 2, [RH, Score=363, Expect=9e-116]} {Dmel: FBgn0000179, bi, bifid, [RH, Score=357, Expect=5e-111]} {Celegans: WBGene00006543, tbx-2, T-box protein 2, [RH, Score=318, Expect=3e-102]} {Smed: dd_Smed_v6_11693_0_1, dd_Smed_v6_11693_0_1, [RH, Score=395, Expect=2e-129]} {RNA1509_33164} {RNA1310_57171} {RNA815_39333}
79. MligTC455_48269 56 1.17 Mlig455_062018, Mlig455_067367

Neo: -

Age: -

1.671 - - - 0.962 0.709 -

Mlig455_062018 {REF} {Length: 2100} {RNA1310_13886} {RNA815_37155}

Mlig455_067367 {REF} {Length: 2213} {RNA1310_13886} {RNA815_37155}
80. MligTC455_27151 2425 50.53 Mlig455_010141

Neo: Int S/G2/M

Age: logFC(26M/2M)=-1.620

Region-enriched R3: 6.747/0.00000
Region-enriched R2: 6.319/0.00053

1.665 - - - 0.957 - 0.708 Mlig455_010141 {REF} {Length: 873} {RNA1509_6591} {RNA1310_101555} {RNA815_33850}
81. MligTC455_19470 80 1.66 Mlig455_002707

Neo: -

Age: -

1.657 0.706 - 0.951 - - - Mlig455_002707 {REF} {Length: 260} {NoTransDecoderORF} {RNA1509_46200} {RNA1310_613.1} {RNA815_5431}
82. MligTC455_14576 9 0.19 Mlig455_030513

Neo: -

Age: -

KCNH4 0.992 - - - - 0.992 - Mlig455_030513 {REF} {Length: 3573} {Pfam: Ion transport protein [PF00520.33, score=103.8]; PAS domain [PF13426.9, score=64.8]; Ion channel [PF07885.18, score=44.1]; Cyclic nucleotide-binding domain [PF00027.31, score=34.1]; PAS fold [PF08448.12, score=19.3]; PAS fold [PF00989.27, score=19.1]} {Human: ENSG00000089558, KCNH4, potassium voltage-gated channel subfamily H member 4, [Score=683, Expect=0.0]} {Mouse: ENSMUSG00000035580, Kcnh8, potassium voltage-gated channel, subfamily H (eag-related), member 8, [RH, Score=558, Expect=0.0]} {Dmel: FBgn0011589, Elk, Eag-like K[+] channel, [Score=718, Expect=0.0]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=433, Expect=7e-137]} {Smed: dd_Smed_v6_14863_0_2, dd_Smed_v6_14863_0_2, [Score=806, Expect=0.0]} {RNA1509_55158} {RNA1310_6929.2} {RNA815_22299}
83. MligTC455_41054 33 0.7 Mlig455_029071

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.560

SLC24A2 0.978 0.978 - - - - - Mlig455_029071 {REF} {Length: 3162} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=167.5]} {Human: ENSG00000155886, SLC24A2, solute carrier family 24 member 2, [Score=280, Expect=2e-84]} {Mouse: ENSMUSG00000037996, Slc24a2, solute carrier family 24 (sodium/potassium/calcium exchanger), member 2, [Score=278, Expect=8e-84]} {Dmel: FBgn0028704, Nckx30C, [Score=254, Expect=2e-73]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=236, Expect=6e-69]} {Smed: dd_Smed_v6_9736_0_1, dd_Smed_v6_9736_0_1, [RH, Score=532, Expect=0.0]} {RNA1509_23781} {RNA1310_15750.1, RNA1509_23781} {RNA1509_23781, RNA815_4071}
84. MligTC455_48128 18 0.37 Mlig455_052326

Neo: -

Age: -

0.978 0.978 - - - - - Mlig455_052326 {REF} {Length: 3582} {RNA1310_42908} {RNA815_22744}
85. MligTC455_03359 17 0.35 Mlig455_037386

Neo: -

Age: -

0.972 - - - 0.972 - - Mlig455_037386 {REF} {Length: 1323} {Pfam: Lectin C-type domain [PF00059.23, score=22.2]} {RNA1310_22051} {RNA815_28288}
86. MligTC455_34315 256 5.34 Mlig455_061276, Mlig455_061312

Neo: -

Age: -

0.972 - - - - - 0.972

Mlig455_061276 {REF} {Length: 1989} {RNA1509_48329} {RNA1310_18117} {RNA815_28436}

Mlig455_061312 {REF} {Length: 2156} {RNA1509_48329} {RNA1310_18117} {RNA815_28436}
87. MligTC455_34316 68 1.42 Mlig455_062660

Neo: -

Age: -

0.972 - - - - - 0.972 Mlig455_062660 {REF} {Length: 1710} {TRANSSPLICED} {RNA1509_48329} {RNA1310_18117} {RNA815_28436}
88. MligTC455_44868 14 0.3 Mlig455_051869, Mlig455_053148

Neo: -

Age: -

CALM1, CALM2 0.972 0.972 - - - - -

Mlig455_051869 {REF} {Length: 320} {Pfam: EF hand [PF00036.34, score=79.1]; EF-hand domain pair [PF13499.8, score=77.0]; EF-hand domain pair [PF13833.8, score=75.0]; EF hand [PF13202.8, score=66.9]; EF-hand domain [PF13405.8, score=65.8]; EF-hand domain [PF14658.8, score=30.2]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=23.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=21.9]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=103, Expect=1e-28]; ENSG00000198668, CALM1, calmodulin 1, [Score=102, Expect=3e-29]; ENSG00000160014, CALM3, calmodulin 3, [Score=102, Expect=3e-29]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=102, Expect=2e-29]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=102, Expect=6e-29]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=102, Expect=6e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=103, Expect=3e-29]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=102, Expect=9e-30]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=102, Expect=2e-29]} {RNA1509_22382} {RNA1310_25980} {RNA815_41318}

Mlig455_053148 {REF} {Length: 916} {Pfam: EF-hand domain pair [PF13499.8, score=114.2]; EF hand [PF00036.34, score=114.0]; EF-hand domain [PF13405.8, score=97.8]; EF-hand domain pair [PF13833.8, score=92.0]; EF hand [PF13202.8, score=81.7]; EF-hand domain [PF14658.8, score=53.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=32.9]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.7]; Caleosin related protein [PF05042.15, score=27.0]; Tellurite resistance protein TerB [PF05099.15, score=19.6]} {Human: ENSG00000198668, CALM1, calmodulin 1, [Score=172, Expect=2e-55]; ENSG00000160014, CALM3, calmodulin 3, [Score=172, Expect=2e-55]; ENSG00000143933, CALM2, calmodulin 2, [Score=172, Expect=2e-55]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=172, Expect=1e-55]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=172, Expect=1e-55]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=172, Expect=1e-55]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=172, Expect=5e-56]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=172, Expect=4e-56]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=172, Expect=3e-56]} {RNA1509_22382} {RNA1310_25980} {RNA815_41318}
89. MligTC455_28262 42 0.87 Mlig455_009098

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=2.413

0.971 - - - - - 0.971 Mlig455_009098 {REF} {Length: 2205} {RNA1310_39210} {RNA815_22102}
90. MligTC455_32974 14 0.29 Mlig455_062705

Neo: -

Age: -

0.969 0.969 - - - - - Mlig455_062705 {REF} {Length: 3220} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=44.3]} {Smed: dd_Smed_v6_41498_0_1, dd_Smed_v6_41498_0_1, [RH, Score=200, Expect=5e-57]} {RNA1509_58337} {RNA1310_20568.1, RNA1509_58337} {RNA1509_58337, RNA815_54575}
91. MligTC455_45730 87 1.81 Mlig455_020296

Neo: -

Age: Down-Up-Up

Region-enriched R2: 8.589/0.00002

SSUH2 0.969 0.969 - - - - - Mlig455_020296 {REF} {Length: 1680} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=197, Expect=3e-59]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=155, Expect=9e-44]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=127, Expect=5e-33]} {RNA1310_19609.2} {RNA815_22113.1}
92. MligTC455_28598 102 2.13 Mlig455_057552

Neo: -

Age: -

0.968 - - 0.968 - - - Mlig455_057552 {REF} {Length: 3851} {TRANSSPLICED} {RNA1509_60109} {RNA1310_21727} {RNA815_11299}
93. MligTC455_47735 70 1.45 Mlig455_054644

Neo: -

Age: -

Region-enriched R3: 5.950/0.00023

0.968 - - - 0.968 - - Mlig455_054644 {REF} {Length: 804} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=37.7]} {RNA1509_39145} {RNA1310_42379.1} {RNA815_34286.1}
94. MligTC455_52493 6 0.13 Mlig455_058213

Neo: -

Age: -

0.968 0.968 - - - - - Mlig455_058213 {REF} {Length: 1454} {Smed: dd_Smed_v6_25969_0_1, dd_Smed_v6_25969_0_1, [Score=79.0, Expect=3e-16]} {RNA1310_119010}
95. MligTC455_03958 11 0.23 Mlig455_013433

Neo: -

Age: -

ADRA2A 0.967 - - - 0.967 - - Mlig455_013433 {REF} {Length: 2048} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=99.7]} {Human: ENSG00000150594, ADRA2A, adrenoceptor alpha 2A, [Score=76.6, Expect=2e-14]} {Mouse: ENSMUSG00000033717, Adra2a, adrenergic receptor, alpha 2a, [Score=70.1, Expect=2e-12]} {Dmel: FBgn0036934, sNPF-R, short neuropeptide F receptor, [Score=64.7, Expect=8e-11]} {Celegans: WBGene00003808, npr-2, NeuroPeptide Receptor family, [Score=61.2, Expect=6e-10]} {Smed: dd_Smed_v6_16129_0_1, dd_Smed_v6_16129_0_1, [RH, Score=208, Expect=5e-63]} {RNA1310_76491} {RNA815_33424}
96. MligTC455_09127 11 0.24 Mlig455_051263

Neo: -

Age: -

TBX2 0.967 - - - 0.967 - - Mlig455_051263 {REF} {Length: 2970} {Pfam: T-box [PF00907.24, score=269.9]} {Human: ENSG00000121068, TBX2, T-box 2, [RH, Score=364, Expect=3e-116]; ENSG00000135111, TBX3, T-box 3, [RH, Score=356, Expect=6e-113]} {Mouse: ENSMUSG00000018604, Tbx3, T-box 3, [RH, Score=365, Expect=1e-116]; ENSMUSG00000000093, Tbx2, T-box 2, [RH, Score=363, Expect=1e-115]} {Dmel: FBgn0000179, bi, bifid, [RH, Score=357, Expect=6e-111]} {Celegans: WBGene00006543, tbx-2, T-box protein 2, [RH, Score=318, Expect=3e-102]} {Smed: dd_Smed_v6_11693_0_1, dd_Smed_v6_11693_0_1, [RH, Score=395, Expect=2e-129]} {RNA1509_33164} {RNA1310_57171} {RNA815_39333}
97. MligTC455_12811 22 0.46 Mlig455_011326

Neo: -

Age: -

0.967 - - - 0.967 - - Mlig455_011326 {REF} {Length: 917} {NoTransDecoderORF} {RNA1509_21597} {RNA1310_28238} {RNA815_48996}
98. MligTC455_41882 38 0.79 Mlig455_068617

Neo: -

Age: Down-Up-Down

FGFR1OP 0.967 - - - 0.967 - - Mlig455_068617 {REF} {Length: 3810} {Pfam: FOP N terminal dimerisation domain [PF09398.12, score=38.7]; LisH [PF16045.7, score=17.7]} {Human: ENSG00000213066, FGFR1OP, FGFR1 oncogene partner, [RH, Score=100, Expect=1e-22]} {Mouse: ENSMUSG00000069135, Fgfr1op, Fgfr1 oncogene partner, [RH, Score=97.4, Expect=1e-21]} {Smed: dd_Smed_v6_5371_0_1, dd_Smed_v6_5371_0_1, [Score=57.4, Expect=5e-09]} {RNA1509_14615} {RNA1310_14786} {RNA815_10750}
99. MligTC455_11698 105 2.19 Mlig455_024131, Mlig455_054470

Neo: -

Age: -

Region-enriched R2: 12.016/0.00001

0.966 0.966 - - - - -

Mlig455_024131 {REF} {Length: 399} {RNA1509_2588} {RNA1310_120080} {RNA815_53081}

Mlig455_054470 {REF} {Length: 369} {RNA1509_2588} {RNA1310_120080} {RNA815_53081}
100. MligTC455_16050 56 1.17 Mlig455_005538, Mlig455_015621, Mlig455_064144

Neo: -

Age: Down-Up-Down

0.966 0.966 - - - - -

Mlig455_005538 {REF} {Length: 2036} {RNA1509_38546} {RNA1310_1911.1} {RNA815_61177}

Mlig455_015621 {REF} {Length: 2076} {RNA1509_38546} {RNA1310_1911.1} {RNA815_61177}

Mlig455_064144 {REF} {Length: 2045} {RNA1509_38546} {RNA1310_1911.1} {RNA815_61177}

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