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Results for MligTC455_18541

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_18541 1108 23.09 Mlig455_003326

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.290

Region-enriched R2: 4.433/0.00000
Region-enriched R3: 3.875/0.00000

SFRP2 Mlig455_003326 {REF} {Length: 2658} {TRANSSPLICED} {Pfam: Fz domain [PF01392.24, score=86.0]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [RH, Score=167, Expect=4e-46]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [RH, Score=165, Expect=2e-45]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=101, Expect=8e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=1e-44]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [RH, Score=157, Expect=1e-42]} {RNA1509_5709} {RNA1310_15264} {RNA815_7067}

Cumulative graph for MligTC455_18541

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.839 4.77 0.12406 0.71803
RegionR2 4.433 4.77 0.00000 0.00000
RegionR3 3.875 4.77 0.00000 0.00000
RegionR4 0.526 4.77 0.44409 0.77284
RegionR5 -0.668 4.77 0.95445 1.00000
RegionR6 -0.88 4.77 0.97282 1.00000
RegionR7 -2.529 4.77 1.00000 1.00000
RegionR8 -6.594 4.77 0.00732 0.15797

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -2.269 4.77 0.14282 0.88236
RegenerationR2 -0.756 4.77 0.05472 0.38557
RegenerationR3 -0.335 4.77 0.41497 0.81189
RegenerationR4 0.163 4.77 0.74150 0.96797
RegenerationR5 0.461 4.77 0.37998 0.78677
RegenerationR6 -0.16 4.77 0.81947 0.98651
RegenerationBL 1.643 4.77 0.27959 0.64031
RegenerationTP 3.529 4.77 0.04552 0.35396


Genes with expression patterns similar to MligTC455_18541

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_18541 1108 23.09 Mlig455_003326

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.290

Region-enriched R2: 4.433/0.00000
Region-enriched R3: 3.875/0.00000

SFRP2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_003326 {REF} {Length: 2658} {TRANSSPLICED} {Pfam: Fz domain [PF01392.24, score=86.0]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [RH, Score=167, Expect=4e-46]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [RH, Score=165, Expect=2e-45]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=101, Expect=8e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=1e-44]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [RH, Score=157, Expect=1e-42]} {RNA1509_5709} {RNA1310_15264} {RNA815_7067}
2. MligTC455_18539 1250 26.03 Mlig455_003030

Neo: -

Age: logFC(26M/2M)=-0.308

Region-specific R2: 5.210

Region-enriched R2: 4.715/0.00000
Region-enriched R3: 3.959/0.00000

SFRP2 4.475 - 0.961 0.731 0.841 0.953 0.989 Mlig455_003030 {REF} {Length: 2108} {Pfam: Fz domain [PF01392.24, score=88.0]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [RH, Score=166, Expect=7e-48]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [RH, Score=165, Expect=2e-47]; ENSMUSG00000031548, Sfrp1, secreted frizzled-related protein 1, [RH, Score=157, Expect=2e-44]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=100, Expect=2e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=6e-47]} {Smed: dd_Smed_v6_8832_0_1, dd_Smed_v6_8832_0_1, [RH, Score=153, Expect=4e-43]} {RNA1509_32854, RNA1509_44148, RNA1509_5709} {RNA1310_15264, RNA1509_32854, RNA1509_44148, RNA1509_5709} {RNA1509_32854, RNA1509_44148, RNA1509_5709, RNA815_7067}
3. MligTC455_18540 1213 25.28 Mlig455_003235

Neo: -

Age: -

Region-specific R2: 5.238

Region-enriched R2: 4.787/0.00000
Region-enriched R3: 3.982/0.00000

SFRP2 4.462 - 0.962 0.724 0.841 0.947 0.988 Mlig455_003235 {REF} {Length: 1691} {TRANSSPLICED} {Pfam: Fz domain [PF01392.24, score=86.0]} {Human: ENSG00000145423, SFRP2, secreted frizzled related protein 2, [RH, Score=167, Expect=4e-46]} {Mouse: ENSMUSG00000027996, Sfrp2, secreted frizzled-related protein 2, [RH, Score=165, Expect=2e-45]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=101, Expect=8e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=1e-44]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [RH, Score=157, Expect=1e-42]} {RNA1509_5709} {RNA1310_15264} {RNA815_7067}
4. MligTC455_39781 4052 84.43 Mlig455_031206

Neo: -

Age: -

Region-specific R2: 2.205

Region-enriched R2: 1.861/0.00000

CLVS2 4.309 0.964 0.949 - 0.768 0.876 0.752 Mlig455_031206 {REF} {Length: 2771} {Pfam: CRAL/TRIO domain [PF00650.22, score=62.0]} {Human: ENSG00000146352, CLVS2, clavesin 2, [Score=112, Expect=5e-28]; ENSG00000177182, CLVS1, clavesin 1, [Score=112, Expect=9e-28]; ENSG00000124120, TTPAL, alpha tocopherol transfer protein like, [Score=110, Expect=3e-27]} {Mouse: ENSMUSG00000019785, Clvs2, clavesin 2, [Score=112, Expect=4e-28]; ENSMUSG00000041216, Clvs1, clavesin 1, [Score=111, Expect=1e-27]; ENSMUSG00000017679, Ttpal, tocopherol (alpha) transfer protein-like, [Score=110, Expect=3e-27]} {Dmel: FBgn0036289, CG10657, [RH, Score=120, Expect=3e-31]} {Smed: dd_Smed_v6_12402_0_3, dd_Smed_v6_12402_0_3, [RH, Score=241, Expect=7e-78]} {RNA1509_17672, RNA1509_26784, RNA1509_33745, RNA1509_3681, RNA1509_37291, RNA1509_38202} {RNA1310_7594.1, RNA1509_17672, RNA1509_26784, RNA1509_33745, RNA1509_3681, RNA1509_37291, RNA1509_38202} {RNA1509_17672, RNA1509_26784, RNA1509_33745, RNA1509_3681, RNA1509_37291, RNA1509_38202, RNA815_4242.1}
5. MligTC455_48523 615 12.81 Mlig455_027573

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.661

Region-enriched R2: 5.785/0.00008
Region-enriched R3: 3.161/0.04686

4.18 - 0.791 0.969 0.786 0.817 0.817 Mlig455_027573 {REF} {Length: 1106} {TRANSSPLICED} {Pfam: N-formylglutamate amidohydrolase [PF05013.14, score=30.2]} {RNA1509_25119, RNA1509_35691, RNA1509_59740} {RNA1310_12591, RNA1509_25119, RNA1509_35691, RNA1509_59740} {RNA1509_25119, RNA1509_35691, RNA1509_59740, RNA815_14574}
6. MligTC455_22214 237 4.94 Mlig455_019333, Mlig455_019447

Neo: -

Age: -

NRG2 3.265 0.879 0.713 - 0.714 0.959 -

Mlig455_019333 {REF} {Length: 4291} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=50.5]; Immunoglobulin domain [PF13927.8, score=44.7]; Immunoglobulin domain [PF00047.27, score=43.9]; Immunoglobulin domain [PF13895.8, score=22.0]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=86.7, Expect=8e-17]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [RH, Score=81.3, Expect=2e-15]} {Dmel: FBgn0005666, bt, bent, [Score=52.0, Expect=2e-06]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=51.2, Expect=3e-06]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [Score=55.1, Expect=9e-08]} {RNA1509_54517} {RNA1310_8322} {RNA815_13786}

Mlig455_019447 {REF} {Length: 4242} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=50.5]; Immunoglobulin domain [PF13927.8, score=44.8]; Immunoglobulin domain [PF00047.27, score=43.9]; Immunoglobulin domain [PF13895.8, score=22.1]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=18.6]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=88.6, Expect=2e-17]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [RH, Score=83.2, Expect=7e-16]} {Dmel: FBgn0005666, bt, bent, [Score=52.4, Expect=2e-06]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=51.2, Expect=3e-06]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [Score=55.1, Expect=9e-08]} {RNA1509_54517} {RNA1310_8322} {RNA815_13786}
7. MligTC455_19938 250 5.2 Mlig455_063706

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.458

Region-enriched R3: 3.513/0.03723

NKX2-2 2.727 - 0.935 - 0.821 - 0.971 Mlig455_063706 {REF} {Length: 2739} {Pfam: Homeodomain [PF00046.31, score=72.6]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [Score=119, Expect=3e-31]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [Score=119, Expect=1e-31]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [Score=112, Expect=2e-27]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=95.9, Expect=8e-23]} {Smed: dd_Smed_v6_2716_0_4, dd_Smed_v6_2716_0_4, [Score=118, Expect=4e-30]} {RNA1509_27298} {RNA1310_16689.1, RNA1509_27298} {RNA1509_27298, RNA815_30453}
8. MligTC455_38228 1245 25.95 Mlig455_062302

Neo: -

Age: -

Region-specific R2: 4.636

Region-enriched R2: 3.645/0.00011
Region-enriched R3: 2.442/0.00111

2.605 0.872 - - 0.780 0.953 - Mlig455_062302 {REF} {Length: 725} {RNA1509_22173, RNA1509_33106} {RNA1310_65747, RNA1509_22173, RNA1509_33106} {RNA1509_22173, RNA1509_33106, RNA815_15489}
9. MligTC455_16692 3051 63.56 Mlig455_019404, Mlig455_059069

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.530

Region-enriched R2: 2.591/0.00008
Region-enriched R3: 1.913/0.00155

2.583 - - 0.972 0.786 0.825 -

Mlig455_019404 {REF} {Length: 549} {RNA1509_7240} {RNA1310_72042} {RNA815_55066}

Mlig455_059069 {REF} {Length: 629} {RNA1509_7240} {RNA1310_72042, RNA1509_7240} {RNA1509_7240, RNA815_55066}
10. MligTC455_19795 50 1.05 Mlig455_015163, Mlig455_015285

Neo: -

Age: Up-Down-Down

2.554 - 0.712 - - 0.882 0.960

Mlig455_015163 {REF} {Length: 4537} {TRANSSPLICED} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=183.2]} {Smed: dd_Smed_v6_23771_0_1, dd_Smed_v6_23771_0_1, [RH, Score=366, Expect=7e-119]} {RNA1509_44797} {RNA1310_13221} {RNA815_45407}

Mlig455_015285 {REF} {Length: 4094} {TRANSSPLICED} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=183.3]} {Smed: dd_Smed_v6_23771_0_1, dd_Smed_v6_23771_0_1, [RH, Score=366, Expect=9e-119]} {RNA1509_57431} {RNA1310_13221} {RNA815_45407}
11. MligTC455_54064 85 1.76 Mlig455_002543, Mlig455_002586

Neo: -

Age: -

Region-enriched R8: 4.573/0.01369

2.53 - 0.820 - 0.752 0.958 -

Mlig455_002543 {REF} {Length: 2311} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=32.4]} {RNA1310_11536} {RNA815_6619.1}

Mlig455_002586 {REF} {Length: 2383} {RNA1310_11536} {RNA815_6619.1}
12. MligTC455_10060 252 5.25 Mlig455_045586, Mlig455_045588, Mlig455_045645

Neo: -

Age: -

Region-enriched R3: 5.577/0.00014
Region-enriched R2: 5.093/0.02849

2.521 - - 0.951 0.776 - 0.794

Mlig455_045586 {REF} {Length: 436} {NoTransDecoderORF} {RNA1310_84637} {RNA815_42836.2}

Mlig455_045588 {REF} {Length: 472} {RNA1310_84637} {RNA815_42836.2}

Mlig455_045645 {REF} {Length: 489} {RNA1310_84637} {RNA815_42836.2}
13. MligTC455_47393 241 5.03 Mlig455_008718, Mlig455_063579

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.683/0.00849

CALM2 2.497 - 0.732 - 0.810 0.955 -

Mlig455_008718 {REF} {Length: 1727} {Pfam: EF hand [PF00036.34, score=99.3]; EF-hand domain pair [PF13499.8, score=95.1]; EF-hand domain [PF13405.8, score=86.1]; EF-hand domain pair [PF13833.8, score=76.8]; EF hand [PF13202.8, score=75.3]; EF-hand domain [PF14658.8, score=46.0]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.9]; EF-hand domain [PF08976.13, score=23.4]; Uncharacterised protein family (UPF0154) [PF03672.15, score=18.7]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=108, Expect=4e-30]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=4e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=4e-30]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-30]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=108, Expect=2e-30]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=1e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-30]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-30]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=114, Expect=8e-33]} {RNA1310_33847.1} {RNA815_17211}

Mlig455_063579 {REF} {Length: 2562} {Pfam: EF hand [PF00036.34, score=95.8]; EF-hand domain pair [PF13499.8, score=92.8]; EF-hand domain [PF13405.8, score=82.9]; EF-hand domain pair [PF13833.8, score=74.4]; EF hand [PF13202.8, score=72.2]; EF-hand domain [PF14658.8, score=43.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.6]; EF-hand domain [PF08976.13, score=21.4]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=111, Expect=7e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=3e-29]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=3e-29]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=111, Expect=7e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-29]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-29]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=9e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-29]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-29]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=111, Expect=9e-31]} {RNA1310_12431.1} {RNA815_17211}
14. MligTC455_22041 600 12.5 Mlig455_004510, Mlig455_064179

Neo: -

Age: -

Region-enriched R4: 3.769/0.03840

PLA2G12A 2.42 - 0.704 0.981 - - 0.735

Mlig455_004510 {REF} {Length: 2035} {Pfam: Group XII secretory phospholipase A2 precursor (PLA2G12) [PF06951.13, score=119.6]} {Human: ENSG00000123739, PLA2G12A, phospholipase A2 group XIIA, [RH, Score=102, Expect=9e-27]} {Mouse: ENSMUSG00000027999, Pla2g12a, phospholipase A2, group XIIA, [RH, Score=103, Expect=4e-27]} {Dmel: FBgn0036545, GXIVsPLA2, [Score=86.3, Expect=2e-20]} {RNA1509_25279} {RNA1310_35538.1} {RNA815_22770.1}

Mlig455_064179 {REF} {Length: 2163} {Pfam: Group XII secretory phospholipase A2 precursor (PLA2G12) [PF06951.13, score=119.6]} {Human: ENSG00000123739, PLA2G12A, phospholipase A2 group XIIA, [RH, Score=102, Expect=9e-27]} {Mouse: ENSMUSG00000027999, Pla2g12a, phospholipase A2, group XIIA, [RH, Score=103, Expect=4e-27]} {Dmel: FBgn0036545, GXIVsPLA2, [Score=86.3, Expect=2e-20]} {RNA1509_25279} {RNA1310_35538.1} {RNA815_22770.1}
15. MligTC455_42777 776 16.16 Mlig455_061330, Mlig455_061351, Mlig455_062681

Neo: -

Age: -

Region-enriched R2: 2.412/0.00354

Regeneration-downregulated BL: -7.472

Regeneration-depleted BL: -7.472

HPCA, KCNIP3 2.394 0.704 - - - 0.955 0.735

Mlig455_061330 {REF} {Length: 3398} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=54.3]; EF hand [PF00036.34, score=44.6]; EF-hand domain [PF13405.8, score=40.1]; EF hand [PF13202.8, score=22.1]} {Human: ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=53.9, Expect=1e-08]; ENSG00000138472, GUCA1C, guanylate cyclase activator 1C, [Score=52.4, Expect=2e-08]} {Mouse: ENSMUSG00000079056, Kcnip3, Kv channel interacting protein 3, calsenilin, [Score=51.6, Expect=4e-08]} {Dmel: FBgn0265595, CG44422, [Score=53.1, Expect=1e-08]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=48.5, Expect=2e-07]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [Score=47.4, Expect=3e-07]} {RNA1509_44520, RNA1509_55897} {RNA1310_41409.1, RNA1509_55897} {RNA1509_55897, RNA815_23006}

Mlig455_061351 {REF} {Length: 2885} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=53.9]; EF hand [PF00036.34, score=44.8]; EF-hand domain [PF13405.8, score=40.1]; EF hand [PF13202.8, score=22.3]} {Human: ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=53.9, Expect=1e-08]; ENSG00000138472, GUCA1C, guanylate cyclase activator 1C, [Score=53.1, Expect=1e-08]} {Mouse: ENSMUSG00000079056, Kcnip3, Kv channel interacting protein 3, calsenilin, [Score=51.6, Expect=5e-08]} {Dmel: FBgn0265595, CG44422, [Score=49.7, Expect=2e-07]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=48.9, Expect=1e-07]} {RNA1509_55897} {RNA1310_41409.2} {RNA815_23006}

Mlig455_062681 {REF} {Length: 1756} {Pfam: EF-hand domain pair [PF13499.8, score=54.6]; EF hand [PF00036.34, score=44.6]; EF-hand domain [PF13405.8, score=40.1]; EF hand [PF13202.8, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.1]} {Human: ENSG00000121905, HPCA, hippocalcin, [Score=57.0, Expect=4e-10]; ENSG00000104490, NCALD, neurocalcin delta, [Score=55.5, Expect=1e-09]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=54.3, Expect=4e-09]} {Mouse: ENSMUSG00000020907, Rcvrn, recoverin, [Score=57.0, Expect=3e-10]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=57.0, Expect=3e-10]; ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=55.5, Expect=9e-10]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=54.7, Expect=2e-09]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=53.9, Expect=2e-09]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=48.5, Expect=2e-07]} {Smed: dd_Smed_v6_2568_0_1, dd_Smed_v6_2568_0_1, [Score=51.2, Expect=1e-08]} {RNA1509_44520} {RNA1310_41409.1, RNA1509_44520} {RNA1509_44520, RNA815_23006}
16. MligTC455_19937 67 1.4 Mlig455_048004

Neo: -

Age: Down-Up-Down

Region-enriched R4: 5.334/0.01237

NKX2-2 1.811 - 0.840 - - - 0.971 Mlig455_048004 {REF} {Length: 2666} {Pfam: Homeodomain [PF00046.31, score=72.6]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [Score=119, Expect=2e-31]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [Score=119, Expect=1e-31]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [Score=112, Expect=1e-27]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=95.5, Expect=9e-23]} {Smed: dd_Smed_v6_2716_0_3, dd_Smed_v6_2716_0_3, [Score=118, Expect=4e-30]} {RNA1509_27298} {RNA1310_16689.1} {RNA815_30453}
17. MligTC455_31695 158 3.3 Mlig455_009775

Neo: -

Age: Down-Up-Up

Region-enriched R2: 3.086/0.01194

1.736 - - - 0.776 0.960 - Mlig455_009775 {REF} {Length: 2186} {RNA1310_24838} {RNA815_18727}
18. MligTC455_35019 168 3.49 Mlig455_046994

Neo: -

Age: -

ASIC4 1.674 - - - 0.720 0.954 - Mlig455_046994 {REF} {Length: 4001} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=101.4]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=76.3, Expect=1e-13]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=76.3, Expect=8e-14]; ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=72.8, Expect=8e-13]} {Smed: dd_Smed_v6_15233_0_1, dd_Smed_v6_15233_0_1, [RH, Score=103, Expect=1e-22]} {RNA1509_33816} {RNA1310_3176, RNA1509_33816} {RNA1509_33816, RNA815_12439}
19. MligTC455_21812 20 0.42 Mlig455_019683

Neo: -

Age: -

NMUR2 1.658 - - - 0.701 - 0.957 Mlig455_019683 {REF} {Length: 2876} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=154.7]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=22.7]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=22.5]; Olfactory receptor [PF13853.8, score=21.0]} {Human: ENSG00000132911, NMUR2, neuromedin U receptor 2, [RH, Score=172, Expect=2e-48]} {Mouse: ENSMUSG00000026237, Nmur1, neuromedin U receptor 1, [RH, Score=173, Expect=4e-49]} {Dmel: FBgn0037100, CapaR, Capability receptor, [RH, Score=210, Expect=1e-62]} {Celegans: WBGene00019616, nmur-2, NMUR (NeuroMedin U Receptor) homolog, [RH, Score=209, Expect=4e-63]} {Smed: dd_Smed_v6_17801_0_1, dd_Smed_v6_17801_0_1, [RH, Score=257, Expect=1e-81]} {RNA1310_96825}
20. MligTC455_03892 8 0.18 Mlig455_009194

Neo: -

Age: -

0.986 - - - - 0.986 - Mlig455_009194 {REF} {Length: 2218} {TRANSSPLICED} {Dmel: FBgn0035248, CG13919, [RH, Score=45.4, Expect=1e-05]} {Smed: dd_Smed_v6_16261_0_1, dd_Smed_v6_16261_0_1, [RH, Score=255, Expect=7e-81]} {RNA1509_28905} {RNA1310_72348.1} {RNA815_44982}
21. MligTC455_11914 37 0.76 Mlig455_044332

Neo: -

Age: -

HSPB8 0.982 - - - - 0.982 - Mlig455_044332 {REF} {Length: 1369} {Pfam: Hsp20/alpha crystallin family [PF00011.23, score=94.7]; HSP20-like domain found in ArsA [PF17886.3, score=28.4]} {Human: ENSG00000152137, HSPB8, heat shock protein family B (small) member 8, [Score=47.4, Expect=5e-06]} {Mouse: ENSMUSG00000041548, Hspb8, heat shock protein 8, [Score=47.8, Expect=3e-06]; ENSMUSG00000006221, Hspb7, heat shock protein family, member 7 (cardiovascular), [Score=45.8, Expect=9e-06]} {Dmel: FBgn0035817, CG7409, [RH, Score=56.6, Expect=8e-10]} {Celegans: WBGene00008592, F08H9.4, [RH, Score=61.2, Expect=1e-11]} {Smed: dd_Smed_v6_5406_0_1, dd_Smed_v6_5406_0_1, [Score=103, Expect=3e-26]} {RNA1310_50408} {RNA815_48338}
22. MligTC455_03895 18 0.37 Mlig455_009197, Mlig455_009619

Neo: -

Age: Down-Up-Down

0.978 - - - - 0.978 -

Mlig455_009197 {REF} {Length: 1774} {Smed: dd_Smed_v6_16261_0_1, dd_Smed_v6_16261_0_1, [Score=254, Expect=7e-82]} {RNA1310_72348.1} {RNA815_44982}

Mlig455_009619 {REF} {Length: 1794} {Smed: dd_Smed_v6_16261_0_1, dd_Smed_v6_16261_0_1, [Score=254, Expect=7e-82]} {RNA1310_72348.1} {RNA815_44982}
23. MligTC455_24782 16 0.33 Mlig455_071168

Neo: -

Age: logFC(26M/2M)=-0.351

TTLL3 0.97 - - - - 0.970 - Mlig455_071168 {REF} {Length: 3703} {TRANSSPLICED} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=244.7]; YheC/D like ATP-grasp [PF14398.8, score=21.6]} {Human: ENSG00000214021, TTLL3, tubulin tyrosine ligase like 3, [RH, Score=467, Expect=1e-152]; ENSG00000138892, TTLL8, tubulin tyrosine ligase like 8, [RH, Score=453, Expect=2e-144]} {Mouse: ENSMUSG00000030276, Ttll3, tubulin tyrosine ligase-like family, member 3, [RH, Score=507, Expect=3e-164]} {Dmel: FBgn0031854, TTLL3A, Tubulin tyrosine ligase-like 3A, [Score=363, Expect=1e-109]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [Score=114, Expect=8e-27]} {Smed: dd_Smed_v6_10244_0_1, dd_Smed_v6_10244_0_1, [RH, Score=612, Expect=0.0]} {RNA1509_24586, RNA1509_8170} {RNA1310_3446.1, RNA1509_24586} {RNA1509_24586, RNA815_867}
24. MligTC455_25200 17 0.36 Mlig455_054567

Neo: -

Age: -

0.968 - - - - - 0.968 Mlig455_054567 {REF} {Length: 992} {NoTransDecoderORF} {RNA1509_11398} {RNA1310_877.1} {RNA815_745}
25. MligTC455_53895 21 0.43 Mlig455_053958

Neo: -

Age: -

0.968 - - - - 0.968 - Mlig455_053958 {REF} {Length: 208} {NoTransDecoderORF} {RNA1310_28234} {RNA815_49657}
26. MligTC455_13125 9 0.18 Mlig455_054783

Neo: -

Age: -

ASIC1 0.967 - - - - 0.967 - Mlig455_054783 {REF} {Length: 2108} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=41.1]} {Human: ENSG00000110881, ASIC1, acid sensing ion channel subunit 1, [Score=46.6, Expect=1e-05]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=47.8, Expect=3e-06]} {Smed: dd_Smed_v6_16557_0_1, dd_Smed_v6_16557_0_1, [Score=94.0, Expect=4e-22]}
27. MligTC455_12107 15 0.32 Mlig455_053747

Neo: -

Age: -

GABRA4 0.965 - - - - 0.965 - Mlig455_053747 {REF} {Length: 2104} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=155.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=95.4]} {Human: ENSG00000109158, GABRA4, gamma-aminobutyric acid type A receptor alpha4 subunit, [RH, Score=294, Expect=6e-93]; ENSG00000113327, GABRG2, gamma-aminobutyric acid type A receptor gamma2 subunit, [RH, Score=285, Expect=3e-90]} {Mouse: ENSMUSG00000029211, Gabra4, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4, [RH, Score=291, Expect=7e-92]; ENSMUSG00000020436, Gabrg2, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2, [RH, Score=279, Expect=2e-88]} {Dmel: FBgn0030707, CG8916, [Score=345, Expect=2e-113]} {Celegans: WBGene00008551, lgc-36, Ligand-Gated ion Channel, [RH, Score=276, Expect=1e-86]} {Smed: dd_Smed_v6_24908_0_1, dd_Smed_v6_24908_0_1, [Score=399, Expect=3e-136]} {RNA1310_12235.2} {RNA815_15667.1}
28. MligTC455_42104 25 0.52 Mlig455_057718

Neo: -

Age: -

ARID3A 0.965 - - - - 0.965 - Mlig455_057718 {REF} {Length: 2795} {Pfam: ARID/BRIGHT DNA binding domain [PF01388.23, score=72.5]} {Human: ENSG00000116017, ARID3A, AT-rich interaction domain 3A, [RH, Score=244, Expect=2e-71]; ENSG00000205143, ARID3C, AT-rich interaction domain 3C, [RH, Score=242, Expect=1e-72]} {Mouse: ENSMUSG00000019564, Arid3a, AT rich interactive domain 3A (BRIGHT-like), [RH, Score=247, Expect=1e-72]; ENSMUSG00000066224, Arid3c, AT rich interactive domain 3C (BRIGHT-like), [RH, Score=245, Expect=2e-74]} {Dmel: FBgn0004795, retn, retained, [RH, Score=241, Expect=2e-68]} {Celegans: WBGene00000476, cfi-1, AT-rich interactive domain-containing protein cfi-1, [RH, Score=231, Expect=3e-68]} {Smed: dd_Smed_v6_13474_0_1, dd_Smed_v6_13474_0_1, [RH, Score=259, Expect=1e-77]} {RNA1509_54880} {RNA1310_44805} {RNA815_49768}
29. MligTC455_23983 21 0.44 Mlig455_025539, Mlig455_025557

Neo: -

Age: -

0.963 - - - - 0.963 -

Mlig455_025539 {REF} {Length: 532} {NoTransDecoderORF}

Mlig455_025557 {REF} {Length: 3448} {RNA1509_50956} {RNA1310_70245} {RNA815_29876}
30. MligTC455_33623 4 0.09 Mlig455_029437

Neo: -

Age: -

TRHR 0.962 - - - - - 0.962 Mlig455_029437 {REF} {Length: 1495} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=59.8]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=32.8]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=32.5]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=28.4]} {Human: ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=48.9, Expect=1e-05]} {Mouse: ENSMUSG00000038760, Trhr, thyrotropin releasing hormone receptor, [Score=50.1, Expect=4e-06]; ENSMUSG00000052821, Cysltr1, cysteinyl leukotriene receptor 1, [Score=48.5, Expect=9e-06]} {Celegans: WBGene00022004, npr-22, NeuroPeptide Receptor family, [Score=51.6, Expect=6e-07]} {Smed: dd_Smed_v6_15884_0_1, dd_Smed_v6_15884_0_1, [Score=79.3, Expect=5e-16]} {RNA1310_109944}
31. MligTC455_33936 62 1.29 Mlig455_061181

Neo: -

Age: Down-Down-Up

Region-enriched R3: 4.766/0.00000

0.961 - - - - - 0.961 Mlig455_061181 {REF} {Length: 2443} {Pfam: Fibronectin type II domain [PF00040.21, score=54.5]} {Mouse: ENSMUSG00000054580, Pla2r1, phospholipase A2 receptor 1, [Score=50.1, Expect=2e-06]} {RNA1310_23349.1} {RNA815_44226.1}
32. MligTC455_44962 43 0.9 Mlig455_045953

Neo: -

Age: -

0.959 - - - - 0.959 - Mlig455_045953 {REF} {Length: 2329} {RNA1310_33363.2} {RNA815_25152}
33. MligTC455_09473 19 0.39 Mlig455_050329

Neo: -

Age: -

0.956 - - - - 0.956 - Mlig455_050329 {REF} {Length: 660} {NoTransDecoderORF} {RNA1509_9817} {RNA1310_86966} {RNA815_34606}
34. MligTC455_25886 17 0.35 Mlig455_028578, Mlig455_056909

Neo: -

Age: -

IGFALS, VASN 0.956 - - - - - 0.956

Mlig455_028578 {REF} {Length: 2425} {Pfam: Tetraspanin family [PF00335.22, score=98.0]; Leucine rich repeat [PF13855.8, score=91.1]; Leucine Rich repeats (2 copies) [PF12799.9, score=40.8]; Leucine-rich repeat [PF14580.8, score=22.3]} {Human: ENSG00000099769, IGFALS, insulin like growth factor binding protein acid labile subunit, [Score=67.0, Expect=6e-11]} {Mouse: ENSMUSG00000046070, Igfals, insulin-like growth factor binding protein, acid labile subunit, [Score=71.6, Expect=1e-12]} {Dmel: FBgn0029114, Tollo, [Score=69.7, Expect=6e-12]} {Celegans: WBGene00008093, lron-1, ELRR (Extracellular Leucine-Rich Repeat) ONly, [Score=54.7, Expect=1e-07]} {Smed: dd_Smed_v6_1378_0_1, dd_Smed_v6_1378_0_1, [Score=84.0, Expect=1e-17]} {RNA1509_54214} {RNA1310_24542} {RNA815_8809.1}

Mlig455_056909 {REF} {Length: 3265} {Pfam: Tetraspanin family [PF00335.22, score=91.6]; Leucine rich repeat [PF13855.8, score=91.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=39.5]; Leucine-rich repeat [PF14580.8, score=23.9]} {Human: ENSG00000168140, VASN, vasorin, [Score=71.2, Expect=3e-12]; ENSG00000274334, VASN, vasorin, [Score=71.2, Expect=3e-12]} {Mouse: ENSMUSG00000046070, Igfals, insulin-like growth factor binding protein, acid labile subunit, [Score=69.3, Expect=9e-12]; ENSMUSG00000063765, Chadl, chondroadherin-like, [Score=68.9, Expect=1e-11]; ENSMUSG00000039646, Vasn, vasorin, [Score=68.9, Expect=1e-11]; ENSMUSG00000023176, Cpn2, carboxypeptidase N, polypeptide 2, [Score=67.0, Expect=3e-11]} {Dmel: FBgn0029114, Tollo, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00011345, dma-1, [Score=52.4, Expect=8e-07]} {Smed: dd_Smed_v6_6669_0_1, dd_Smed_v6_6669_0_1, [Score=88.2, Expect=6e-18]} {RNA1509_54214} {RNA1310_15547} {RNA815_8809.1}
35. MligTC455_28262 42 0.87 Mlig455_009098

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=2.413

0.956 - - - - - 0.956 Mlig455_009098 {REF} {Length: 2205} {RNA1310_39210} {RNA815_22102}
36. MligTC455_52255 215 4.48 Mlig455_020595

Neo: -

Age: -

0.955 - - - - 0.955 - Mlig455_020595 {REF} {Length: 2601} {Pfam: TIR domain [PF13676.8, score=69.5]; BTK motif [PF00779.21, score=29.8]; TIR domain [PF01582.22, score=24.8]} {Smed: dd_Smed_v6_4452_0_1, dd_Smed_v6_4452_0_1, [Score=70.9, Expect=1e-12]} {RNA1509_54137} {RNA1310_8917.1} {RNA815_7724}
37. MligTC455_20724 290 6.05 Mlig455_026646

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.281

CCDC62 0.953 - - - - 0.953 - Mlig455_026646 {REF} {Length: 2624} {Human: ENSG00000130783, CCDC62, coiled-coil domain containing 62, [RH, Score=117, Expect=9e-27]} {Mouse: ENSMUSG00000061882, Ccdc62, coiled-coil domain containing 62, [RH, Score=122, Expect=2e-28]} {RNA1509_10483, RNA1509_39993} {RNA1310_6237.1, RNA1509_10483, RNA1509_39993} {RNA1509_10483, RNA1509_39993, RNA815_13573}
38. MligTC455_43117 761 15.85 Mlig455_020048

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.232

Region-enriched R4: 2.195/0.00074

SYT2 0.953 - - - - 0.953 - Mlig455_020048 {REF} {Length: 2219} {Pfam: C2 domain [PF00168.32, score=73.7]} {Human: ENSG00000143858, SYT2, synaptotagmin 2, [Score=66.2, Expect=4e-11]} {Mouse: ENSMUSG00000026452, Syt2, synaptotagmin II, [Score=66.2, Expect=3e-11]} {Dmel: FBgn0004242, Syt1, Synaptotagmin 1, [Score=53.5, Expect=2e-07]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=70.9, Expect=6e-13]} {Smed: dd_Smed_v6_4222_0_1, dd_Smed_v6_4222_0_1, [Score=64.7, Expect=4e-11]} {RNA1509_15684} {RNA1310_6450.1} {RNA815_4385}
39. MligTC455_35893 13 0.27 Mlig455_000160

Neo: -

Age: logFC(26M/2M)=-0.311

LDB3 0.952 - - - - 0.952 - Mlig455_000160 {REF} {Length: 1707} {Pfam: PDZ domain [PF00595.26, score=50.4]; Domain of unknown function (DUF4749) [PF15936.7, score=28.1]} {Human: ENSG00000122367, LDB3, LIM domain binding 3, [RH, Score=77.8, Expect=4e-15]} {Mouse: ENSMUSG00000021798, Ldb3, LIM domain binding 3, [RH, Score=78.2, Expect=8e-16]} {Dmel: FBgn0035917, Zasp66, Z band alternatively spliced PDZ-motif protein 66, [Score=77.0, Expect=1e-15]} {Celegans: WBGene00010444, magi-1, MAGI (Membrane Associated Guanylate kinase Inverted) homolog, [Score=48.1, Expect=9e-06]} {Smed: dd_Smed_v6_1210_0_1, dd_Smed_v6_1210_0_1, [RH, Score=117, Expect=1e-28]} {RNA1509_22686} {RNA1310_5136, RNA1509_22686} {RNA1509_22686, RNA815_1546.1}

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