Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_20073 | 1050 | 21.88 | Mlig455_021812 | Neo: - Age: - |
CWC22 | Mlig455_021812 {REF} {Length: 2402} {TRANSSPLICED} {Pfam: MA3 domain [PF02847.19, score=86.0]; MIF4G domain [PF02854.21, score=48.8]} {Human: ENSG00000163510, CWC22, CWC22 spliceosome associated protein homolog, [RH, Score=568, Expect=0.0]} {Mouse: ENSMUSG00000027014, Cwc22, CWC22 spliceosome-associated protein, [RH, Score=564, Expect=0.0]; ENSMUSG00000096729, Gm13695, predicted gene 13695, [RH, Score=561, Expect=0.0]; ENSMUSG00000094336, Gm13693, predicted gene 13693, [RH, Score=561, Expect=0.0]; ENSMUSG00000094125, Gm13698, predicted gene 13698, [RH, Score=561, Expect=0.0]; ENSMUSG00000096484, Gm13696, predicted gene 13696, [RH, Score=561, Expect=0.0]; ENSMUSG00000096337, Gm13694, predicted gene 13694, [RH, Score=561, Expect=0.0]; ENSMUSG00000095824, Gm13697, predicted gene 13697, [RH, Score=561, Expect=0.0]; ENSMUSG00000079247, Gm13691, predicted gene 13691, [RH, Score=561, Expect=0.0]} {Dmel: FBgn0086707, ncm, nucampholin, [RH, Score=566, Expect=0.0]} {Celegans: WBGene00002957, let-858, Pre-mRNA-splicing factor CWC22 homolog, [RH, Score=503, Expect=7e-168]} {Smed: dd_Smed_v6_5597_0_1, dd_Smed_v6_5597_0_1, [RH, Score=471, Expect=4e-159]} {RNA1509_42093, RNA1509_7437} {RNA1310_7876, RNA1509_42093, RNA1509_7437} {RNA1509_42093, RNA1509_7437, RNA815_2944} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.272 | 4.741 | 0.76919 | 1.00000 | |
RegionR2 | 0.053 | 4.741 | 0.89384 | 1.00000 | |
RegionR3 | -0.036 | 4.741 | 0.91444 | 1.00000 | |
RegionR4 | 0.124 | 4.741 | 0.73259 | 1.00000 | |
RegionR5 | 0.622 | 4.741 | 0.02754 | 0.12184 | |
RegionR6 | -0.117 | 4.741 | 0.73231 | 1.00000 | |
RegionR7 | 0.022 | 4.741 | 0.96047 | 1.00000 | |
RegionR8 | -0.396 | 4.741 | 0.52232 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -1.885 | 4.741 | 0.23795 | 0.96582 | |
RegenerationR2 | 0.148 | 4.741 | 0.65423 | 0.93808 | |
RegenerationR3 | 0.084 | 4.741 | 0.81498 | 0.98623 | |
RegenerationR4 | 0.124 | 4.741 | 0.72773 | 0.96401 | |
RegenerationR5 | 0.029 | 4.741 | 0.92836 | 1.00000 | |
RegenerationR6 | 0.64 | 4.741 | 0.07487 | 0.34210 | |
RegenerationBL | 0.641 | 4.741 | 0.13020 | 0.42989 | |
RegenerationTP | 0.277 | 4.741 | 0.57373 | 0.94648 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_20073 | 1050 | 21.88 | Mlig455_021812 | Neo: - Age: - |
CWC22 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_021812 {REF} {Length: 2402} {TRANSSPLICED} {Pfam: MA3 domain [PF02847.19, score=86.0]; MIF4G domain [PF02854.21, score=48.8]} {Human: ENSG00000163510, CWC22, CWC22 spliceosome associated protein homolog, [RH, Score=568, Expect=0.0]} {Mouse: ENSMUSG00000027014, Cwc22, CWC22 spliceosome-associated protein, [RH, Score=564, Expect=0.0]; ENSMUSG00000096729, Gm13695, predicted gene 13695, [RH, Score=561, Expect=0.0]; ENSMUSG00000094336, Gm13693, predicted gene 13693, [RH, Score=561, Expect=0.0]; ENSMUSG00000094125, Gm13698, predicted gene 13698, [RH, Score=561, Expect=0.0]; ENSMUSG00000096484, Gm13696, predicted gene 13696, [RH, Score=561, Expect=0.0]; ENSMUSG00000096337, Gm13694, predicted gene 13694, [RH, Score=561, Expect=0.0]; ENSMUSG00000095824, Gm13697, predicted gene 13697, [RH, Score=561, Expect=0.0]; ENSMUSG00000079247, Gm13691, predicted gene 13691, [RH, Score=561, Expect=0.0]} {Dmel: FBgn0086707, ncm, nucampholin, [RH, Score=566, Expect=0.0]} {Celegans: WBGene00002957, let-858, Pre-mRNA-splicing factor CWC22 homolog, [RH, Score=503, Expect=7e-168]} {Smed: dd_Smed_v6_5597_0_1, dd_Smed_v6_5597_0_1, [RH, Score=471, Expect=4e-159]} {RNA1509_42093, RNA1509_7437} {RNA1310_7876, RNA1509_42093, RNA1509_7437} {RNA1509_42093, RNA1509_7437, RNA815_2944} |
2. | MligTC455_32550 | 924 | 19.24 | Mlig455_019608 | Neo: - Age: Down-Down-Up |
KAT8 | 2.541 | - | - | - | 0.973 | 0.726 | 0.842 | Mlig455_019608 {REF} {Length: 2694} {TRANSSPLICED} {Pfam: MOZ/SAS family [PF01853.20, score=270.3]} {Human: ENSG00000103510, KAT8, lysine acetyltransferase 8, [Score=299, Expect=2e-99]} {Mouse: ENSMUSG00000030801, Kat8, K(lysine) acetyltransferase 8, [Score=298, Expect=2e-99]} {Dmel: FBgn0014340, mof, males absent on the first, [Score=281, Expect=5e-89]} {Celegans: WBGene00010537, mys-2, Histone acetyltransferase, [Score=236, Expect=7e-75]} {Smed: dd_Smed_v6_10027_0_1, dd_Smed_v6_10027_0_1, [Score=288, Expect=3e-96]} {RNA1509_14301} {RNA1310_7249.1} {RNA815_4204.1} |
3. | MligTC455_32551 | 1629 | 33.95 | Mlig455_019384, Mlig455_059089 | Neo: - Age: - |
KAT8 | 2.521 | - | - | - | 0.973 | 0.720 | 0.828 | Mlig455_019384 {REF} {Length: 1850} {TRANSSPLICED} {Pfam: MOZ/SAS family [PF01853.20, score=268.6]; MYST family zinc finger domain [PF17772.3, score=83.4]; RNA binding activity-knot of a chromodomain [PF11717.10, score=62.5]} {Human: ENSG00000103510, KAT8, lysine acetyltransferase 8, [RH, Score=464, Expect=1e-161]} {Mouse: ENSMUSG00000030801, Kat8, K(lysine) acetyltransferase 8, [RH, Score=464, Expect=7e-162]} {Dmel: FBgn0014340, mof, males absent on the first, [RH, Score=416, Expect=2e-138]} {Celegans: WBGene00010537, mys-2, Histone acetyltransferase, [RH, Score=324, Expect=3e-106]} {Smed: dd_Smed_v6_10027_0_1, dd_Smed_v6_10027_0_1, [RH, Score=427, Expect=4e-148]} {RNA1509_14301, RNA1509_33671, RNA1509_52466} {RNA1310_7249.1, RNA1509_33671, RNA1509_52466} {RNA1509_33671, RNA1509_52466, RNA815_4204.1} Mlig455_059089 {REF} {Length: 1822} {TRANSSPLICED} {Pfam: MOZ/SAS family [PF01853.20, score=268.6]; MYST family zinc finger domain [PF17772.3, score=83.4]; RNA binding activity-knot of a chromodomain [PF11717.10, score=62.5]} {Human: ENSG00000103510, KAT8, lysine acetyltransferase 8, [RH, Score=464, Expect=1e-161]} {Mouse: ENSMUSG00000030801, Kat8, K(lysine) acetyltransferase 8, [RH, Score=464, Expect=7e-162]} {Dmel: FBgn0014340, mof, males absent on the first, [RH, Score=416, Expect=2e-138]} {Celegans: WBGene00010537, mys-2, Histone acetyltransferase, [RH, Score=324, Expect=3e-106]} {Smed: dd_Smed_v6_10027_0_1, dd_Smed_v6_10027_0_1, [RH, Score=427, Expect=4e-148]} {RNA1509_33671} {RNA1310_7249.1} {RNA815_4204.1} |
4. | MligTC455_52125 | 467 | 9.73 | Mlig455_019381 | Neo: Int S/G2/M Age: Up-Down-Up |
TTC37 | 1.789 | - | - | - | - | 0.811 | 0.978 | Mlig455_019381 {REF} {Length: 4479} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=72.5]; Tetratricopeptide repeat [PF00515.30, score=65.3]; Tetratricopeptide repeat [PF13431.8, score=59.0]; TPR repeat [PF13414.8, score=50.1]; Tetratricopeptide repeat [PF13181.8, score=50.0]; Tetratricopeptide repeat [PF13371.8, score=43.7]; Tetratricopeptide repeat [PF14559.8, score=36.3]; Tetratricopeptide repeat [PF13432.8, score=30.4]; Tetratricopeptide repeat [PF13428.8, score=28.4]; Tetratricopeptide repeat [PF13174.8, score=25.9]; Tetratricopeptide repeat [PF13176.8, score=24.9]} {Human: ENSG00000198677, TTC37, tetratricopeptide repeat domain 37, [RH, Score=111, Expect=7e-24]} {Mouse: ENSMUSG00000033991, Ttc37, tetratricopeptide repeat domain 37, [RH, Score=112, Expect=2e-24]} {Dmel: FBgn0033376, CG8777, [RH, Score=108, Expect=2e-23]} {RNA1509_6117} {RNA1310_1556.1} {RNA815_497.1} |
5. | MligTC455_41609 | 1411 | 29.4 | Mlig455_005643, Mlig455_008677, Mlig455_008681 | Neo: - Age: Down-Up-Down Region-enriched R5: 2.013/0.00317 |
1.702 | - | - | - | - | 0.957 | 0.745 | Mlig455_005643 {REF} {Length: 2329} {TRANSSPLICED} {RNA1509_20030} {RNA1310_15398} {RNA815_6047} Mlig455_008677 {REF} {Length: 1876} {TRANSSPLICED} {RNA1509_20030} {RNA1310_15398, RNA1509_20030} {RNA1509_20030, RNA815_6047} Mlig455_008681 {REF} {Length: 2131} {TRANSSPLICED} {RNA1509_20030} {RNA1310_15398} {RNA815_6047} |
|
6. | MligTC455_35658 | 668 | 13.91 | Mlig455_043971 | Neo: Int S/G2/M Age: Up-Down-Down |
MDN1 | 1.685 | - | - | - | 0.965 | 0.720 | - | Mlig455_043971 {REF} {Length: 15304} {Pfam: AAA domain (dynein-related subfamily) [PF07728.16, score=397.0]; Midasin AAA lid domain [PF17867.3, score=130.9]; ATPase family associated with various cellular activities (AAA) [PF07726.13, score=108.6]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=103.6]; AAA ATPase domain [PF13191.8, score=87.8]; P-loop containing dynein motor region [PF12775.9, score=72.0]; AAA domain [PF13401.8, score=71.4]; Midasin AAA lid domain [PF17865.3, score=70.7]; AAA domain [PF13238.8, score=60.1]; ABC transporter [PF00005.29, score=53.1]; Sigma-54 interaction domain [PF14532.8, score=52.9]; Threonylcarbamoyl adenosine biosynthesis protein TsaE [PF02367.19, score=52.6]; MoxR domain in the MoxR-vWA-beta-propeller ternary systems [PF20030.1, score=44.8]; AAA domain [PF13173.8, score=42.7]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=40.3]; RNA helicase [PF00910.24, score=39.9]; NACHT domain [PF05729.14, score=38.5]; AAA domain [PF13521.8, score=37.9]; Sigma-54 interaction domain [PF00158.28, score=36.7]; Protein of unknown function (DUF815) [PF05673.15, score=36.4]; RsgA GTPase [PF03193.18, score=35.0]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=35.0]; Rad17 P-loop domain [PF03215.17, score=33.9]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=30.0]; AAA domain [PF13671.8, score=29.7]; P-loop containing region of AAA domain [PF13555.8, score=27.5]; 50S ribosome-binding GTPase [PF01926.25, score=26.1]; Ethanolamine utilisation - propanediol utilisation [PF10662.11, score=25.5]; ATPase domain predominantly from Archaea [PF01637.20, score=25.2]; Magnesium chelatase, subunit ChlI [PF01078.23, score=25.0]; AAA domain [PF13481.8, score=24.5]; Deoxynucleoside kinase [PF01712.21, score=23.7]; AAA domain (Cdc48 subfamily) [PF07724.16, score=21.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=21.8]; Chloramphenicol phosphotransferase-like protein [PF07931.14, score=21.0]; von Willebrand factor type A domain [PF13519.8, score=19.5]; Conserved hypothetical ATP binding protein [PF03029.19, score=18.8]; IstB-like ATP binding protein [PF01695.19, score=18.5]} {Human: ENSG00000112159, MDN1, midasin AAA ATPase 1, [RH, Score=1631, Expect=0.0]} {Mouse: ENSMUSG00000058006, Mdn1, midasin AAA ATPase 1, [RH, Score=1636, Expect=0.0]} {Dmel: FBgn0033661, CG13185, [RH, Score=1326, Expect=0.0]} {Celegans: WBGene00018898, F55F10.1, Midasin, [RH, Score=1130, Expect=0.0]} {Smed: dd_Smed_v6_12419_0_1, dd_Smed_v6_12419_0_1, [RH, Score=899, Expect=0.0]} {RNA1509_16330, RNA1509_3216, RNA1509_44013, RNA1509_48308} {RNA1310_154, RNA1509_16330, RNA1509_44013, RNA1509_48308} {RNA1509_16330, RNA1509_44013, RNA1509_48308, RNA815_8665} |
7. | MligTC455_23766 | 256 | 5.33 | Mlig455_008056 | Neo: - Age: Down-Down-Down |
SLC25A46 | 0.974 | - | - | - | - | 0.974 | - | Mlig455_008056 {REF} {Length: 2118} {Pfam: Mitochondrial carrier protein [PF00153.29, score=50.8]} {Human: ENSG00000164209, SLC25A46, solute carrier family 25 member 46, [RH, Score=277, Expect=1e-89]} {Mouse: ENSMUSG00000024259, Slc25a46, solute carrier family 25, member 46, [RH, Score=281, Expect=2e-91]} {Dmel: FBgn0030717, CG8931, [RH, Score=275, Expect=2e-89]} {Celegans: WBGene00012740, slc-25A46, SLC (SoLute Carrier) homolog, [RH, Score=199, Expect=4e-59]} {Smed: dd_Smed_v6_11392_0_1, dd_Smed_v6_11392_0_1, [RH, Score=251, Expect=1e-80]} {RNA1509_49737} {RNA1310_670.1} {RNA815_2290.1} |
8. | MligTC455_38249 | 462 | 9.63 | Mlig455_019833 | Neo: Int S/G2/M Age: - |
PSME4 | 0.962 | - | - | - | - | 0.962 | - | Mlig455_019833 {REF} {Length: 6694} {TRANSSPLICED} {Pfam: Proteasome-substrate-size regulator, mid region [PF16507.7, score=97.1]; Domain of unknown function (DUF3437) [PF11919.10, score=96.8]; HEAT repeats [PF13646.8, score=20.3]} {Human: ENSG00000068878, PSME4, proteasome activator subunit 4, [Score=193, Expect=1e-48]} {Mouse: ENSMUSG00000040850, Psme4, proteasome (prosome, macropain) activator subunit 4, [Score=196, Expect=6e-50]} {Celegans: WBGene00007588, C14C10.5, [Score=126, Expect=1e-28]} {Smed: dd_Smed_v6_4721_0_1, dd_Smed_v6_4721_0_1, [Score=112, Expect=2e-24]} {RNA1509_2571, RNA1509_48486, RNA1509_59947} {RNA1310_953, RNA1509_2571, RNA1509_48486, RNA1509_59947} {RNA1509_2571, RNA1509_48486, RNA1509_59947, RNA815_281} |
9. | MligTC455_42402 | 164 | 3.41 | Mlig455_035889 | Neo: Int S/G2/M Age: Up-Down-Up |
TFIP11 | 0.952 | - | - | - | - | - | 0.952 | Mlig455_035889 {REF} {Length: 3513} {TRANSSPLICED} {Pfam: GC-rich sequence DNA-binding factor-like protein [PF07842.14, score=91.1]; G-patch domain [PF01585.25, score=50.8]; Tuftelin interacting protein N terminal [PF12457.10, score=43.7]} {Human: ENSG00000100109, TFIP11, tuftelin interacting protein 11, [Score=268, Expect=2e-77]} {Mouse: ENSMUSG00000029345, Tfip11, tuftelin interacting protein 11, [Score=270, Expect=1e-78]} {Dmel: FBgn0024191, sip1, septin interacting protein 1, [Score=250, Expect=2e-71]} {Celegans: WBGene00007412, stip-1, Septin and tuftelin-interacting protein 1 homolog, [Score=237, Expect=5e-67]} {Smed: dd_Smed_v6_5157_0_1, dd_Smed_v6_5157_0_1, [RH, Score=154, Expect=2e-40]} {RNA1509_47556} {RNA1310_5027} {RNA815_24336} |
10. | MligTC455_18148 | 1499 | 31.23 | Mlig455_048309, Mlig455_048353 | Neo: Int S/G2/M Age: - |
U2AF1L5 | 0.951 | - | - | - | - | - | 0.951 | Mlig455_048309 {REF} {Length: 2547} {Pfam: Zinc finger C-x8-C-x5-C-x3-H type (and similar) [PF00642.26, score=51.0]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=28.7]; Torus domain [PF16131.7, score=25.9]; Zinc finger domain [PF18345.3, score=24.1]} {Human: ENSG00000275895, U2AF1L5, U2 small nuclear RNA auxiliary factor 1 like 5, [RH, Score=337, Expect=3e-118]; ENSG00000160201, U2AF1, U2 small nuclear RNA auxiliary factor 1, [RH, Score=337, Expect=3e-118]} {Mouse: ENSMUSG00000061613, U2af1, U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1, [RH, Score=337, Expect=2e-118]; ENSMUSG00000078765, U2af1l4, U2 small nuclear RNA auxiliary factor 1-like 4, [RH, Score=332, Expect=1e-116]; ENSMUSG00000109378, Gm49396, predicted gene, 49396, [RH, Score=332, Expect=1e-116]} {Dmel: FBgn0017457, U2af38, U2 small nuclear riboprotein auxiliary factor 38, [RH, Score=329, Expect=6e-115]} {Celegans: WBGene00006698, uaf-2, U2AF splicing factor, [RH, Score=265, Expect=3e-89]} {Smed: dd_Smed_v6_4061_0_2, dd_Smed_v6_4061_0_2, [RH, Score=361, Expect=3e-128]} {RNA1509_16766, RNA1509_16935} {RNA1310_24807, RNA1509_16766, RNA1509_16935} {RNA1509_16766, RNA1509_16935, RNA815_15940.1} Mlig455_048353 {REF} {Length: 1999} {Pfam: Zinc finger C-x8-C-x5-C-x3-H type (and similar) [PF00642.26, score=51.0]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=28.7]; Torus domain [PF16131.7, score=25.9]; Zinc finger domain [PF18345.3, score=24.1]} {Human: ENSG00000275895, U2AF1L5, U2 small nuclear RNA auxiliary factor 1 like 5, [RH, Score=337, Expect=3e-118]; ENSG00000160201, U2AF1, U2 small nuclear RNA auxiliary factor 1, [RH, Score=337, Expect=3e-118]} {Mouse: ENSMUSG00000061613, U2af1, U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1, [RH, Score=337, Expect=2e-118]; ENSMUSG00000078765, U2af1l4, U2 small nuclear RNA auxiliary factor 1-like 4, [RH, Score=332, Expect=1e-116]; ENSMUSG00000109378, Gm49396, predicted gene, 49396, [RH, Score=332, Expect=1e-116]} {Dmel: FBgn0017457, U2af38, U2 small nuclear riboprotein auxiliary factor 38, [RH, Score=329, Expect=6e-115]} {Celegans: WBGene00006698, uaf-2, U2AF splicing factor, [RH, Score=265, Expect=3e-89]} {Smed: dd_Smed_v6_4061_0_2, dd_Smed_v6_4061_0_2, [RH, Score=361, Expect=3e-128]} {RNA1509_16935} {RNA1310_24807} {RNA815_15940.1} |
11. | MligTC455_18638 | 952 | 19.84 | Mlig455_056168 | Neo: - Age: Down-Down-Up Region-enriched R4: 1.255/0.01107 |
STAMBPL1 | 0.951 | - | - | - | - | - | 0.951 | Mlig455_056168 {REF} {Length: 3070} {TRANSSPLICED} {Pfam: JAB1/Mov34/MPN/PAD-1 ubiquitin protease [PF01398.23, score=57.3]; USP8 dimerisation domain [PF08969.13, score=53.4]; Prokaryotic homologs of the JAB domain [PF14464.8, score=27.9]} {Human: ENSG00000138134, STAMBPL1, STAM binding protein like 1, [RH, Score=245, Expect=3e-77]} {Mouse: ENSMUSG00000024776, Stambpl1, STAM binding protein like 1, [RH, Score=236, Expect=7e-74]} {Dmel: FBgn0039773, CG2224, [RH, Score=253, Expect=7e-81]} {Celegans: WBGene00018135, F37A4.5, [Score=55.8, Expect=1e-08]} {Smed: dd_Smed_v6_6627_0_1, dd_Smed_v6_6627_0_1, [RH, Score=263, Expect=2e-85]} {RNA1509_15062, RNA1509_15651, RNA1509_31802, RNA1509_49002, RNA1509_50118, RNA1509_51230} {RNA1310_20043, RNA1509_15062, RNA1509_15651, RNA1509_31802, RNA1509_49002, RNA1509_50118, RNA1509_51230} {RNA1509_15062, RNA1509_15651, RNA1509_31802, RNA1509_49002, RNA1509_50118, RNA1509_51230, RNA815_10808} |