Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_21782 | 3524 | 73.42 | Mlig455_009440 | Neo: - Age: - Region-enriched R8: 1.988/0.00000 Regeneration-downregulated BL: -1.563 Regeneration-depleted BL: -1.563 |
Mlig455_009440 {REF} {Length: 4558} {Celegans: WBGene00015646, mlt-10, [Score=140, Expect=4e-39]} {RNA1509_14456} {RNA1310_39726.2} {RNA815_19228.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.55 | 6.23 | 0.30564 | 0.95476 | |
RegionR2 | 0.146 | 6.23 | 0.60812 | 0.95645 | |
RegionR3 | -0.718 | 6.23 | 0.00763 | 0.12689 | |
RegionR4 | -0.408 | 6.23 | 0.18692 | 0.46032 | |
RegionR5 | -1.134 | 6.23 | 0.00004 | 0.00074 | |
RegionR6 | -0.493 | 6.23 | 0.06687 | 0.48340 | |
RegionR7 | 1.168 | 6.23 | 0.00001 | 0.00043 | |
RegionR8 | 1.988 | 6.23 | 0.00000 | 0.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.961 | 6.23 | 0.22318 | 0.95604 | |
RegenerationR2 | -0.942 | 6.23 | 0.00244 | 0.07447 | |
RegenerationR3 | -0.608 | 6.23 | 0.06403 | 0.42660 | |
RegenerationR4 | -0.714 | 6.23 | 0.03206 | 0.28930 | |
RegenerationR5 | -0.558 | 6.23 | 0.09275 | 0.46670 | |
RegenerationR6 | -0.802 | 6.23 | 0.01905 | 0.17040 | |
RegenerationBL | -1.563 | 6.23 | 0.00000 | 0.00013 | Specific for BL: -1.563 |
RegenerationTP | -0.725 | 6.23 | 0.01675 | 0.22236 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_21782 | 3524 | 73.42 | Mlig455_009440 | Neo: - Age: - Region-enriched R8: 1.988/0.00000 Regeneration-downregulated BL: -1.563 Regeneration-depleted BL: -1.563 |
6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_009440 {REF} {Length: 4558} {Celegans: WBGene00015646, mlt-10, [Score=140, Expect=4e-39]} {RNA1509_14456} {RNA1310_39726.2} {RNA815_19228.1} | |
2. | MligTC455_44219 | 289 | 6.02 | Mlig455_053855 | Neo: - Age: Up-Down-Down, logFC(26M/2M)=-0.323 Region-enriched R8: 2.811/0.00017 |
CDH23 | 2.812 | 0.950 | - | - | 0.938 | - | 0.924 | Mlig455_053855 {REF} {Length: 9181} {Pfam: Cadherin domain [PF00028.19, score=457.3]; Cadherin-like [PF08266.14, score=40.7]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=538, Expect=6e-156]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=536, Expect=9e-156]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [RH, Score=635, Expect=0.0]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=240, Expect=3e-63]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [RH, Score=749, Expect=0.0]} {RNA1509_10347} {RNA1310_449.1} {RNA815_181} |
3. | MligTC455_41856 | 833 | 17.36 | Mlig455_021126, Mlig455_021127 | Neo: - Age: - Region-enriched R8: 1.453/0.03195 |
2.718 | 0.834 | - | - | 0.963 | - | 0.921 | Mlig455_021126 {REF} {Length: 1683} {Pfam: Profilin [PF00235.21, score=48.7]; Histone H1-like nucleoprotein HC2 [PF07382.13, score=29.2]} {RNA1509_36755} {RNA1310_41040} {RNA815_12700.1} Mlig455_021127 {REF} {Length: 2189} {Pfam: Profilin [PF00235.21, score=49.0]} {RNA1509_11634, RNA1509_36755} {RNA1310_26877, RNA1509_11634, RNA1509_36755} {RNA1509_11634, RNA1509_36755, RNA815_12700.1} |
|
4. | MligTC455_41855 | 700 | 14.59 | Mlig455_007846 | Neo: - Age: Down-Up-Down |
2.649 | 0.791 | - | - | 0.962 | - | 0.896 | Mlig455_007846 {REF} {Length: 2805} {Pfam: Profilin [PF00235.21, score=46.7]} {RNA1509_36755} {RNA1310_26877} {RNA815_12700.1} | |
5. | MligTC455_16034 | 544 | 11.33 | Mlig455_061559 | Neo: - Age: - Region-enriched R8: 4.432/0.00000 |
CASP7 | 2.648 | 0.957 | - | 0.841 | - | - | 0.850 | Mlig455_061559 {REF} {Length: 5521} {Pfam: Caspase domain [PF00656.24, score=76.9]} {Human: ENSG00000165806, CASP7, caspase 7, [Score=85.1, Expect=5e-17]; ENSG00000003400, CASP10, caspase 10, [Score=81.3, Expect=3e-15]; ENSG00000164305, CASP3, caspase 3, [Score=80.9, Expect=5e-16]} {Mouse: ENSMUSG00000025076, Casp7, caspase 7, [Score=82.8, Expect=1e-16]; ENSMUSG00000031628, Casp3, caspase 3, [Score=80.1, Expect=6e-16]} {Dmel: FBgn0019972, Drice, Death related ICE-like caspase, [Score=75.1, Expect=4e-14]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=82.8, Expect=4e-17]} {Smed: dd_Smed_v6_1167_0_1, dd_Smed_v6_1167_0_1, [Score=89.4, Expect=1e-19]} {RNA1509_47042} {RNA1310_6014.2, RNA1509_47042} {RNA1509_47042, RNA815_17780} |
6. | MligTC455_42170 | 342 | 7.12 | Mlig455_038315 | Neo: - Age: Down-Up-Up |
2.612 | 0.730 | 0.920 | - | 0.962 | - | - | Mlig455_038315 {REF} {Length: 2851} {Pfam: Innexin [PF00876.20, score=296.2]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=95.5, Expect=5e-21]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=208, Expect=6e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=276, Expect=2e-87]} {RNA1509_10527, RNA1509_45409} {RNA1310_14408, RNA1509_10527, RNA1509_45409} {RNA1509_10527, RNA1509_45409, RNA815_844.2} | |
7. | MligTC455_51381 | 347 | 7.23 | Mlig455_024564 | Neo: - Age: Down-Up-Down |
2.532 | 0.864 | - | 0.702 | 0.966 | - | - | Mlig455_024564 {REF} {Length: 1946} {Smed: dd_Smed_v6_14508_0_1, dd_Smed_v6_14508_0_1, [RH, Score=73.2, Expect=7e-15]} {RNA1509_27432} {RNA1310_25177} {RNA815_20912} | |
8. | MligTC455_53510 | 405 | 8.43 | Mlig455_039941 | Neo: - Age: Up-Down-Down Region-enriched R8: 3.005/0.01946 |
KREMEN1 | 1.852 | - | - | - | 0.974 | - | 0.878 | Mlig455_039941 {REF} {Length: 4661} {Pfam: WSC domain [PF01822.21, score=619.2]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=66.6, Expect=2e-10]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=63.9, Expect=9e-10]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=71.2, Expect=6e-12]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=52.0, Expect=3e-06]} {RNA1509_15008} {RNA1310_5799, RNA1509_15008} {RNA1509_15008, RNA815_22574} |
9. | MligTC455_46913 | 1375 | 28.65 | Mlig455_030674 | Neo: - Age: Down-Down-Up, logFC(26M/2M)=-0.488 Region-enriched R7: 2.119/0.00056 |
VIT | 1.83 | - | - | - | 0.863 | - | 0.967 | Mlig455_030674 {REF} {Length: 2036} {Pfam: LCCL domain [PF03815.21, score=200.0]; Histone deacetylation protein Rxt3 [PF08642.12, score=96.1]; Bacterial PH domain [PF10756.11, score=26.4]; Pgp3 C-terminal domain [PF05475.13, score=20.9]} {Human: ENSG00000205221, VIT, vitrin, [RH, Score=50.8, Expect=1e-06]} {Mouse: ENSMUSG00000031825, Crispld2, cysteine-rich secretory protein LCCL domain containing 2, [Score=49.7, Expect=8e-06]} {RNA1509_10169} {RNA1310_29404} {RNA815_26218} |
10. | MligTC455_15685 | 62 | 1.3 | Mlig455_011329 | Neo: - Age: - |
NOTCH4 | 1.796 | - | - | - | 0.962 | - | 0.834 | Mlig455_011329 {REF} {Length: 1536} {Pfam: EGF-like domain [PF00008.29, score=24.1]} {Human: ENSG00000232339, NOTCH4, notch 4, [Score=54.3, Expect=5e-08]; ENSG00000206312, NOTCH4, notch 4, [Score=54.3, Expect=5e-08]; ENSG00000223355, NOTCH4, notch 4, [Score=54.3, Expect=5e-08]; ENSG00000234876, NOTCH4, notch 4, [Score=53.9, Expect=5e-08]; ENSG00000204301, NOTCH4, notch 4, [Score=53.9, Expect=5e-08]; ENSG00000235396, NOTCH4, notch 4, [Score=52.4, Expect=2e-07]; ENSG00000148400, NOTCH1, notch 1, [Score=52.0, Expect=2e-07]} {Mouse: ENSMUSG00000038146, Notch3, notch 3, [Score=53.5, Expect=5e-08]; ENSMUSG00000026923, Notch1, notch 1, [Score=52.0, Expect=2e-07]} {RNA1509_48141} {RNA1310_40191} {RNA815_46710} |
11. | MligTC455_44098 | 944 | 19.67 | Mlig455_012843 | Neo: - Age: Down-Down-Up |
GCH1 | 1.762 | - | - | - | 0.960 | 0.802 | - | Mlig455_012843 {REF} {Length: 1400} {Pfam: GTP cyclohydrolase I [PF01227.24, score=246.6]; QueF-like protein [PF14489.8, score=18.8]} {Human: ENSG00000131979, GCH1, GTP cyclohydrolase 1, [RH, Score=307, Expect=2e-106]} {Mouse: ENSMUSG00000037580, Gch1, GTP cyclohydrolase 1, [RH, Score=302, Expect=2e-104]} {Dmel: FBgn0003162, Pu, Punch, [RH, Score=291, Expect=5e-100]} {Celegans: WBGene00000298, cat-4, GTP cyclohydrolase 1, [RH, Score=300, Expect=5e-104]} {Smed: dd_Smed_v6_11172_0_1, dd_Smed_v6_11172_0_1, [RH, Score=296, Expect=8e-103]} {RNA1509_50079} {RNA1310_26106.1} {RNA815_21206} |
12. | MligTC455_40424 | 474 | 9.88 | Mlig455_029322 | Neo: - |
CALM2 | 1.761 | - | 0.810 | - | 0.951 | - | - | Mlig455_029322 {REF} {Length: 1020} {Pfam: EF-hand domain pair [PF13833.8, score=26.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=69.7, Expect=2e-14]; ENSG00000160014, CALM3, calmodulin 3, [Score=68.9, Expect=2e-14]; ENSG00000198668, CALM1, calmodulin 1, [Score=68.9, Expect=2e-14]; ENSG00000178363, CALML3, calmodulin like 3, [Score=68.2, Expect=3e-14]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=70.5, Expect=1e-14]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=68.9, Expect=1e-14]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=68.9, Expect=1e-14]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=67.4, Expect=3e-14]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=67.8, Expect=2e-14]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=67.8, Expect=2e-14]} {RNA1509_16604} {RNA1310_33121} {RNA815_17390} |
13. | MligTC455_39861 | 264 | 5.5 | Mlig455_059014 | Neo: - Age: - |
1.698 | - | - | - | 0.963 | - | 0.735 | Mlig455_059014 {REF} {Length: 2813} {TRANSSPLICED} {RNA1509_22951} {RNA1310_7946} {RNA815_4282} | |
14. | MligTC455_46419 | 3450 | 71.87 | Mlig455_001787 | Neo: - |
ABCB1 | 0.964 | - | - | - | - | - | 0.964 | Mlig455_001787 {REF} {Length: 5707} {TRANSSPLICED} {Pfam: ABC transporter transmembrane region [PF00664.25, score=438.9]; ABC transporter [PF00005.29, score=256.7]; RecF/RecN/SMC N terminal domain [PF02463.21, score=62.1]; AAA ATPase domain [PF13191.8, score=39.3]; AAA domain [PF13401.8, score=33.4]; Predicted ATPase of the ABC class [PF09818.11, score=30.8]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=30.2]; Zeta toxin [PF06414.14, score=27.1]; P-loop containing region of AAA domain [PF13555.8, score=26.2]; AAA domain [PF13604.8, score=24.8]; RsgA GTPase [PF03193.18, score=24.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=24.4]; Rad17 P-loop domain [PF03215.17, score=23.1]; Adenylylsulphate kinase [PF01583.22, score=22.7]; AAA domain [PF13238.8, score=20.8]; Protein of unknown function (DUF815) [PF05673.15, score=19.9]; Putative exonuclease SbcCD, C subunit [PF13558.8, score=19.2]; Phosphoribulokinase / Uridine kinase family [PF00485.20, score=18.8]; ATP synthase alpha/beta family, nucleotide-binding domain [PF00006.27, score=18.7]} {Human: ENSG00000085563, ABCB1, ATP binding cassette subfamily B member 1, [RH, Score=1188, Expect=0.0]; ENSG00000005471, ABCB4, ATP binding cassette subfamily B member 4, [RH, Score=1144, Expect=0.0]} {Mouse: ENSMUSG00000028970, Abcb1b, ATP-binding cassette, sub-family B (MDR/TAP), member 1B, [RH, Score=1180, Expect=0.0]; ENSMUSG00000040584, Abcb1a, ATP-binding cassette, sub-family B (MDR/TAP), member 1A, [RH, Score=1176, Expect=0.0]; ENSMUSG00000042476, Abcb4, ATP-binding cassette, sub-family B (MDR/TAP), member 4, [RH, Score=1139, Expect=0.0]} {Dmel: FBgn0010241, Mdr50, Multi drug resistance 50, [RH, Score=894, Expect=0.0]} {Celegans: WBGene00004003, pgp-9, P-GlycoProtein related, [RH, Score=1137, Expect=0.0]} {Smed: dd_Smed_v6_4124_0_1, dd_Smed_v6_4124_0_1, [RH, Score=1009, Expect=0.0]} {RNA1509_1034, RNA1509_43495, RNA1509_48254} {RNA1310_1064, RNA1509_43495, RNA1509_48254} {RNA1509_43495, RNA1509_48254, RNA815_387.1} |
15. | MligTC455_18050 | 570 | 11.88 | Mlig455_055052 | Neo: - Age: - |
0.958 | - | - | - | - | - | 0.958 | Mlig455_055052 {REF} {Length: 950} {Pfam: PLAC8 family [PF04749.19, score=73.5]; Uncharacterized protein conserved in archaea (DUF2180) [PF09947.11, score=18.7]} {Smed: dd_Smed_v6_743_0_1, dd_Smed_v6_743_0_1, [Score=111, Expect=4e-33]} {RNA1509_44969} {RNA1310_55602} {RNA815_30798} | |
16. | MligTC455_38967 | 71 | 1.48 | Mlig455_060741 | Neo: - Age: Up-Down-Down, logFC(26M/2M)=-0.569 Region-enriched R2: 3.815/0.00926 |
UTRN | 0.953 | - | - | - | 0.953 | - | - | Mlig455_060741 {REF} {Length: 4727} {Pfam: EF-hand [PF09069.13, score=127.4]; EF hand [PF09068.13, score=102.4]; Zinc finger, ZZ type [PF00569.19, score=37.7]; WW domain [PF00397.28, score=18.6]} {Human: ENSG00000152818, UTRN, utrophin, [RH, Score=493, Expect=5e-147]; ENSG00000198947, DMD, dystrophin, [RH, Score=489, Expect=1e-150]} {Mouse: ENSMUSG00000019820, Utrn, utrophin, [RH, Score=493, Expect=2e-156]; ENSMUSG00000045103, Dmd, dystrophin, muscular dystrophy, [RH, Score=487, Expect=3e-145]} {Dmel: FBgn0260003, Dys, Dystrophin, [RH, Score=516, Expect=4e-155]} {Celegans: WBGene00001131, dys-1, Dystrophin-1, [RH, Score=337, Expect=1e-95]} {Smed: dd_Smed_v6_5325_0_6, dd_Smed_v6_5325_0_6, [RH, Score=295, Expect=4e-82]} {RNA1509_38827} {RNA1310_24533} {RNA815_12379} |