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Results for MligTC455_22133

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_22133 5172 107.76 Mlig455_005007, Mlig455_005046, Mlig455_005262

Neo: -

Age: logFC(26M/2M)=-0.260

Region-enriched R7: 1.553/0.00000

Regeneration-downregulated BL: -2.126

Regeneration-depleted BL: -2.126

CPS1

Mlig455_005007 {REF} {Length: 5305} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.5]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.1]; Glutamine amidotransferase class-I [PF00117.30, score=131.3]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.3]; ATP-grasp domain [PF02222.24, score=63.2]; MGS-like domain [PF02142.24, score=48.6]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.5]; Peptidase C26 [PF07722.15, score=18.5]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [RH, Score=1884, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [RH, Score=1883, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1486, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1449, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [RH, Score=2173, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1} {RNA815_289.1}

Mlig455_005046 {REF} {Length: 5312} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.7]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.0]; Glutamine amidotransferase class-I [PF00117.30, score=131.4]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.5]; ATP-grasp domain [PF02222.24, score=63.3]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.7]; Peptidase C26 [PF07722.15, score=18.6]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [Score=1772, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [Score=1772, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1425, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1392, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [Score=2044, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1, RNA1509_878} {RNA1509_878, RNA815_289.1}

Mlig455_005262 {REF} {Length: 5315} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.5]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.1]; Glutamine amidotransferase class-I [PF00117.30, score=131.3]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.3]; ATP-grasp domain [PF02222.24, score=63.2]; MGS-like domain [PF02142.24, score=48.6]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.5]; Peptidase C26 [PF07722.15, score=18.5]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [RH, Score=1884, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [RH, Score=1883, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1486, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1449, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [RH, Score=2173, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1} {RNA815_289.1}

Cumulative graph for MligTC455_22133

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.525 6.927 0.37426 1.00000
RegionR2 0.148 6.927 0.68126 1.00000
RegionR3 0.889 6.927 0.00207 0.05080
RegionR4 -1.041 6.927 0.00805 0.05184
RegionR5 -1.727 6.927 0.00000 0.00002
RegionR6 0.372 6.927 0.21840 0.79797
RegionR7 1.553 6.927 0.00000 0.00000
RegionR8 0.331 6.927 0.36369 0.99790

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -2.647 6.927 0.01681 0.54049
RegenerationR2 -0.769 6.927 0.04546 0.35235
RegenerationR3 -0.086 6.927 0.82607 0.98974
RegenerationR4 -0.045 6.927 0.91491 1.00000
RegenerationR5 0.942 6.927 0.01829 0.23491
RegenerationR6 -0.591 6.927 0.12403 0.43290
RegenerationBL -2.126 6.927 0.00000 0.00003 Specific for BL: -2.126
RegenerationTP -1.08 6.927 0.00617 0.13190


Genes with expression patterns similar to MligTC455_22133

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_22133 5172 107.76 Mlig455_005007, Mlig455_005046, Mlig455_005262

Neo: -

Age: logFC(26M/2M)=-0.260

Region-enriched R7: 1.553/0.00000

Regeneration-downregulated BL: -2.126

Regeneration-depleted BL: -2.126

CPS1 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_005007 {REF} {Length: 5305} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.5]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.1]; Glutamine amidotransferase class-I [PF00117.30, score=131.3]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.3]; ATP-grasp domain [PF02222.24, score=63.2]; MGS-like domain [PF02142.24, score=48.6]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.5]; Peptidase C26 [PF07722.15, score=18.5]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [RH, Score=1884, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [RH, Score=1883, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1486, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1449, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [RH, Score=2173, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1} {RNA815_289.1}

Mlig455_005046 {REF} {Length: 5312} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.7]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.0]; Glutamine amidotransferase class-I [PF00117.30, score=131.4]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.5]; ATP-grasp domain [PF02222.24, score=63.3]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.7]; Peptidase C26 [PF07722.15, score=18.6]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [Score=1772, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [Score=1772, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1425, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1392, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [Score=2044, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1, RNA1509_878} {RNA1509_878, RNA815_289.1}

Mlig455_005262 {REF} {Length: 5315} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.5]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.1]; Glutamine amidotransferase class-I [PF00117.30, score=131.3]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.3]; ATP-grasp domain [PF02222.24, score=63.2]; MGS-like domain [PF02142.24, score=48.6]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.5]; Peptidase C26 [PF07722.15, score=18.5]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [RH, Score=1884, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [RH, Score=1883, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1486, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1449, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [RH, Score=2173, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1} {RNA815_289.1}
2. MligTC455_04509 308 6.42 Mlig455_015097, Mlig455_015215

Neo: -

Age: -

Region-enriched R3: 2.768/0.00001
Region-enriched R7: 2.553/0.00083

Regeneration-downregulated BL: -7.255

Regeneration-depleted BL: -7.255

C1GALT1 3.336 0.767 0.718 - - 0.893 0.958

Mlig455_015097 {REF} {Length: 1363} {Pfam: Galactosyltransferase [PF01762.23, score=33.1]; Fringe-like [PF02434.18, score=32.5]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=162, Expect=2e-46]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=165, Expect=1e-47]} {Dmel: FBgn0032078, C1GalTA, Core 1 Galactosyltransferase A, [Score=183, Expect=3e-54]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=183, Expect=3e-54]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=188, Expect=1e-56]} {RNA1509_52982} {RNA1310_22738.1} {RNA815_21441}

Mlig455_015215 {REF} {Length: 2494} {Pfam: Fringe-like [PF02434.18, score=59.2]; Galactosyltransferase [PF01762.23, score=57.8]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=175, Expect=3e-48]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=172, Expect=1e-47]} {Dmel: FBgn0032078, C1GalTA, Core 1 Galactosyltransferase A, [Score=184, Expect=7e-52]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=183, Expect=2e-51]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=188, Expect=8e-54]} {RNA1509_52982} {RNA1310_22738.1} {RNA815_21441}
3. MligTC455_31059 571 11.9 Mlig455_013389

Neo: -

Age: -

Region-enriched R7: 2.543/0.00000

Regeneration-downregulated BL: -2.866

Regeneration-depleted BL: -2.866

1.855 - - - - 0.900 0.955 Mlig455_013389 {REF} {Length: 3375} {Pfam: Profilin [PF00235.21, score=45.7]} {Smed: dd_Smed_v6_6034_0_1, dd_Smed_v6_6034_0_1, [RH, Score=79.3, Expect=5e-17]} {RNA1509_42370} {RNA1310_22792.1} {RNA815_5445}
4. MligTC455_13800 174 3.62 Mlig455_025213, Mlig455_025646

Neo: -

Age: -

BICDL1 0.971 - - - - 0.971 -

Mlig455_025213 {REF} {Length: 3644} {TRANSSPLICED} {Pfam: Intermediate filament protein [PF00038.23, score=18.6]} {Human: ENSG00000135127, BICDL1, BICD family like cargo adaptor 1, [RH, Score=95.9, Expect=4e-20]} {Mouse: ENSMUSG00000041609, Bicdl1, BICD family like cargo adaptor 1, [RH, Score=95.5, Expect=4e-20]} {Dmel: FBgn0052137, CG32137, [RH, Score=100, Expect=1e-21]} {Smed: dd_Smed_v6_7219_0_1, dd_Smed_v6_7219_0_1, [RH, Score=129, Expect=1e-31]} {RNA1509_34033} {RNA1310_18300.1, RNA1509_34033} {RNA1509_34033, RNA815_35699}

Mlig455_025646 {REF} {Length: 3450} {Pfam: Intermediate filament protein [PF00038.23, score=18.6]} {Human: ENSG00000135127, BICDL1, BICD family like cargo adaptor 1, [RH, Score=95.9, Expect=5e-20]} {Mouse: ENSMUSG00000041609, Bicdl1, BICD family like cargo adaptor 1, [RH, Score=95.5, Expect=5e-20]} {Dmel: FBgn0052137, CG32137, [RH, Score=99.0, Expect=3e-21]} {Smed: dd_Smed_v6_7219_0_1, dd_Smed_v6_7219_0_1, [RH, Score=129, Expect=1e-31]} {RNA1509_34033} {RNA1310_18300.1} {RNA815_35699}
5. MligTC455_39978 270 5.62 Mlig455_052261, Mlig455_052349

Neo: -

Age: Down-Up-Up

Region-enriched R8: 3.650/0.00368
Region-enriched R3: 2.366/0.04725

0.971 - - - - - 0.971

Mlig455_052261 {REF} {Length: 760} {RNA1310_41850} {RNA815_20313}

Mlig455_052349 {REF} {Length: 710} {RNA1310_41850} {RNA815_20313}
6. MligTC455_21050 18 0.37 Mlig455_024510

Neo: -

Age: -

0.97 - - - - - 0.970 Mlig455_024510 {REF} {Length: 2499} {RNA1310_68107} {RNA815_59638}
7. MligTC455_18514 86 1.8 Mlig455_043176

Neo: -

Age: -

CALM2 0.963 - - - - - 0.963 Mlig455_043176 {REF} {Length: 1325} {Pfam: EF hand [PF00036.34, score=110.1]; EF-hand domain pair [PF13499.8, score=108.2]; EF-hand domain [PF13405.8, score=88.2]; EF-hand domain pair [PF13833.8, score=85.7]; EF hand [PF13202.8, score=85.5]; EF-hand domain [PF14658.8, score=46.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=34.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=30.0]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=183, Expect=2e-58]; ENSG00000160014, CALM3, calmodulin 3, [Score=182, Expect=9e-59]; ENSG00000198668, CALM1, calmodulin 1, [Score=182, Expect=9e-59]; ENSG00000178363, CALML3, calmodulin like 3, [Score=177, Expect=6e-57]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=184, Expect=6e-59]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=182, Expect=6e-59]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=182, Expect=6e-59]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=181, Expect=2e-58]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=181, Expect=2e-58]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=180, Expect=3e-58]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=180, Expect=2e-58]} {RNA1509_20574} {RNA1310_23382} {RNA815_12969}
8. MligTC455_48659 72 1.51 Mlig455_038733

Neo: -

Age: -

BMP1 0.955 - - - - - 0.955 Mlig455_038733 {REF} {Length: 2559} {Pfam: CUB domain [PF00431.22, score=55.5]; CD20-like family [PF04103.17, score=19.6]} {Human: ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=73.6, Expect=7e-13]} {Mouse: ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=73.9, Expect=3e-13]} {Dmel: FBgn0004885, tok, tolkin, [Score=59.3, Expect=8e-09]} {Celegans: WBGene00003555, nas-39, Zinc metalloproteinase nas-39, [Score=59.3, Expect=6e-09]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=62.8, Expect=5e-10]} {RNA1509_45794} {RNA1310_15908} {RNA815_14641.1}
9. MligTC455_12359 34 0.71 Mlig455_036860, Mlig455_053000

Neo: -

Age: -

0.953 - - - - 0.953 -

Mlig455_036860 {REF} {Length: 2052} {Pfam: Ammonium Transporter Family [PF00909.23, score=351.9]} {Dmel: FBgn0038309, Amt, Ammonium transporter, [Score=177, Expect=1e-48]} {Celegans: WBGene00000136, amt-4, Ammonium transporter, [Score=361, Expect=7e-119]} {RNA1310_63464} {RNA815_52017}

Mlig455_053000 {REF} {Length: 2052} {Pfam: Ammonium Transporter Family [PF00909.23, score=351.9]} {Dmel: FBgn0038309, Amt, Ammonium transporter, [Score=177, Expect=1e-48]} {Celegans: WBGene00000136, amt-4, Ammonium transporter, [Score=361, Expect=7e-119]} {RNA1310_63464} {RNA815_52017}
10. MligTC455_41126 619 12.9 Mlig455_050185

Neo: -

Age: -

Region-enriched R6: 3.273/0.00035

0.953 - - - - 0.953 - Mlig455_050185 {REF} {Length: 671} {RNA1509_36640} {RNA1310_51392} {RNA815_51264}
11. MligTC455_11780 35 0.73 Mlig455_023335

Neo: -

Age: Down-Up-Down

Regeneration-enriched R4: 10.634
Regeneration-enriched R3: 10.602
Regeneration-enriched R6: 8.985
Regeneration-enriched R5: 6.941

PDE9A 0.951 - - - - 0.951 - Mlig455_023335 {REF} {Length: 3554} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=286.3]} {Human: ENSG00000160191, PDE9A, phosphodiesterase 9A, [Score=544, Expect=0.0]} {Mouse: ENSMUSG00000041119, Pde9a, phosphodiesterase 9A, [Score=549, Expect=0.0]} {Dmel: FBgn0259171, Pde9, Phosphodiesterase 9, [Score=311, Expect=8e-92]} {Celegans: WBGene00020114, pde-4, Probable 3',5'-cyclic phosphodiesterase pde-4, [Score=163, Expect=4e-43]} {Smed: dd_Smed_v6_13304_0_1, dd_Smed_v6_13304_0_1, [Score=298, Expect=3e-93]} {RNA1310_14570} {RNA815_20478}

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