Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_22133 | 5172 | 107.76 | Mlig455_005007, Mlig455_005046, Mlig455_005262 | Neo: - Age: logFC(26M/2M)=-0.260 Region-enriched R7: 1.553/0.00000 Regeneration-downregulated BL: -2.126 Regeneration-depleted BL: -2.126 |
CPS1 | Mlig455_005007 {REF} {Length: 5305} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.5]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.1]; Glutamine amidotransferase class-I [PF00117.30, score=131.3]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.3]; ATP-grasp domain [PF02222.24, score=63.2]; MGS-like domain [PF02142.24, score=48.6]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.5]; Peptidase C26 [PF07722.15, score=18.5]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [RH, Score=1884, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [RH, Score=1883, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1486, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1449, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [RH, Score=2173, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1} {RNA815_289.1} Mlig455_005046 {REF} {Length: 5312} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.7]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.0]; Glutamine amidotransferase class-I [PF00117.30, score=131.4]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.5]; ATP-grasp domain [PF02222.24, score=63.3]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.7]; Peptidase C26 [PF07722.15, score=18.6]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [Score=1772, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [Score=1772, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1425, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1392, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [Score=2044, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1, RNA1509_878} {RNA1509_878, RNA815_289.1} Mlig455_005262 {REF} {Length: 5315} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.5]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.1]; Glutamine amidotransferase class-I [PF00117.30, score=131.3]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.3]; ATP-grasp domain [PF02222.24, score=63.2]; MGS-like domain [PF02142.24, score=48.6]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.5]; Peptidase C26 [PF07722.15, score=18.5]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [RH, Score=1884, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [RH, Score=1883, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1486, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1449, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [RH, Score=2173, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1} {RNA815_289.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.525 | 6.927 | 0.37426 | 1.00000 | |
RegionR2 | 0.148 | 6.927 | 0.68126 | 1.00000 | |
RegionR3 | 0.889 | 6.927 | 0.00207 | 0.05080 | |
RegionR4 | -1.041 | 6.927 | 0.00805 | 0.05184 | |
RegionR5 | -1.727 | 6.927 | 0.00000 | 0.00002 | |
RegionR6 | 0.372 | 6.927 | 0.21840 | 0.79797 | |
RegionR7 | 1.553 | 6.927 | 0.00000 | 0.00000 | |
RegionR8 | 0.331 | 6.927 | 0.36369 | 0.99790 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -2.647 | 6.927 | 0.01681 | 0.54049 | |
RegenerationR2 | -0.769 | 6.927 | 0.04546 | 0.35235 | |
RegenerationR3 | -0.086 | 6.927 | 0.82607 | 0.98974 | |
RegenerationR4 | -0.045 | 6.927 | 0.91491 | 1.00000 | |
RegenerationR5 | 0.942 | 6.927 | 0.01829 | 0.23491 | |
RegenerationR6 | -0.591 | 6.927 | 0.12403 | 0.43290 | |
RegenerationBL | -2.126 | 6.927 | 0.00000 | 0.00003 | Specific for BL: -2.126 |
RegenerationTP | -1.08 | 6.927 | 0.00617 | 0.13190 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_22133 | 5172 | 107.76 | Mlig455_005007, Mlig455_005046, Mlig455_005262 | Neo: - Age: logFC(26M/2M)=-0.260 Region-enriched R7: 1.553/0.00000 Regeneration-downregulated BL: -2.126 Regeneration-depleted BL: -2.126 |
CPS1 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_005007 {REF} {Length: 5305} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.5]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.1]; Glutamine amidotransferase class-I [PF00117.30, score=131.3]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.3]; ATP-grasp domain [PF02222.24, score=63.2]; MGS-like domain [PF02142.24, score=48.6]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.5]; Peptidase C26 [PF07722.15, score=18.5]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [RH, Score=1884, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [RH, Score=1883, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1486, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1449, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [RH, Score=2173, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1} {RNA815_289.1} Mlig455_005046 {REF} {Length: 5312} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.7]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.0]; Glutamine amidotransferase class-I [PF00117.30, score=131.4]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.5]; ATP-grasp domain [PF02222.24, score=63.3]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.7]; Peptidase C26 [PF07722.15, score=18.6]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [Score=1772, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [Score=1772, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1425, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1392, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [Score=2044, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1, RNA1509_878} {RNA1509_878, RNA815_289.1} Mlig455_005262 {REF} {Length: 5315} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=368.5]; Carbamoyl-phosphate synthase small chain, CPSase domain [PF00988.24, score=165.1]; Glutamine amidotransferase class-I [PF00117.30, score=131.3]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain [PF02787.21, score=78.8]; D-ala D-ala ligase C-terminus [PF07478.15, score=63.3]; ATP-grasp domain [PF02222.24, score=63.2]; MGS-like domain [PF02142.24, score=48.6]; ATP-grasp in the biosynthetic pathway with Ter operon [PF15632.8, score=42.5]; Peptidase C26 [PF07722.15, score=18.5]} {Human: ENSG00000021826, CPS1, carbamoyl-phosphate synthase 1, [RH, Score=1884, Expect=0.0]} {Mouse: ENSMUSG00000025991, Cps1, carbamoyl-phosphate synthetase 1, [RH, Score=1883, Expect=0.0]} {Dmel: FBgn0003189, r, rudimentary, [Score=1486, Expect=0.0]} {Celegans: WBGene00004259, pyr-1, CAD protein Glutamine-dependent carbamoyl-phosphate synthase Aspartate carbamoyltransferase Dihydroorotase, [Score=1449, Expect=0.0]} {Smed: dd_Smed_v6_4349_0_1, dd_Smed_v6_4349_0_1, [RH, Score=2173, Expect=0.0]} {RNA1509_878} {RNA1310_1011.1} {RNA815_289.1} |
2. | MligTC455_04509 | 308 | 6.42 | Mlig455_015097, Mlig455_015215 | Neo: - Age: - Region-enriched R3: 2.768/0.00001 Regeneration-downregulated BL: -7.255 Regeneration-depleted BL: -7.255 |
C1GALT1 | 3.336 | 0.767 | 0.718 | - | - | 0.893 | 0.958 | Mlig455_015097 {REF} {Length: 1363} {Pfam: Galactosyltransferase [PF01762.23, score=33.1]; Fringe-like [PF02434.18, score=32.5]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=162, Expect=2e-46]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=165, Expect=1e-47]} {Dmel: FBgn0032078, C1GalTA, Core 1 Galactosyltransferase A, [Score=183, Expect=3e-54]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=183, Expect=3e-54]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=188, Expect=1e-56]} {RNA1509_52982} {RNA1310_22738.1} {RNA815_21441} Mlig455_015215 {REF} {Length: 2494} {Pfam: Fringe-like [PF02434.18, score=59.2]; Galactosyltransferase [PF01762.23, score=57.8]} {Human: ENSG00000106392, C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=175, Expect=3e-48]} {Mouse: ENSMUSG00000042460, C1galt1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, [Score=172, Expect=1e-47]} {Dmel: FBgn0032078, C1GalTA, Core 1 Galactosyltransferase A, [Score=184, Expect=7e-52]} {Celegans: WBGene00008019, C38H2.2, Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, [Score=183, Expect=2e-51]} {Smed: dd_Smed_v6_4310_0_1, dd_Smed_v6_4310_0_1, [Score=188, Expect=8e-54]} {RNA1509_52982} {RNA1310_22738.1} {RNA815_21441} |
3. | MligTC455_31059 | 571 | 11.9 | Mlig455_013389 | Neo: - Age: - Region-enriched R7: 2.543/0.00000 Regeneration-downregulated BL: -2.866 Regeneration-depleted BL: -2.866 |
1.855 | - | - | - | - | 0.900 | 0.955 | Mlig455_013389 {REF} {Length: 3375} {Pfam: Profilin [PF00235.21, score=45.7]} {Smed: dd_Smed_v6_6034_0_1, dd_Smed_v6_6034_0_1, [RH, Score=79.3, Expect=5e-17]} {RNA1509_42370} {RNA1310_22792.1} {RNA815_5445} | |
4. | MligTC455_13800 | 174 | 3.62 | Mlig455_025213, Mlig455_025646 | Neo: - Age: - |
BICDL1 | 0.971 | - | - | - | - | 0.971 | - | Mlig455_025213 {REF} {Length: 3644} {TRANSSPLICED} {Pfam: Intermediate filament protein [PF00038.23, score=18.6]} {Human: ENSG00000135127, BICDL1, BICD family like cargo adaptor 1, [RH, Score=95.9, Expect=4e-20]} {Mouse: ENSMUSG00000041609, Bicdl1, BICD family like cargo adaptor 1, [RH, Score=95.5, Expect=4e-20]} {Dmel: FBgn0052137, CG32137, [RH, Score=100, Expect=1e-21]} {Smed: dd_Smed_v6_7219_0_1, dd_Smed_v6_7219_0_1, [RH, Score=129, Expect=1e-31]} {RNA1509_34033} {RNA1310_18300.1, RNA1509_34033} {RNA1509_34033, RNA815_35699} Mlig455_025646 {REF} {Length: 3450} {Pfam: Intermediate filament protein [PF00038.23, score=18.6]} {Human: ENSG00000135127, BICDL1, BICD family like cargo adaptor 1, [RH, Score=95.9, Expect=5e-20]} {Mouse: ENSMUSG00000041609, Bicdl1, BICD family like cargo adaptor 1, [RH, Score=95.5, Expect=5e-20]} {Dmel: FBgn0052137, CG32137, [RH, Score=99.0, Expect=3e-21]} {Smed: dd_Smed_v6_7219_0_1, dd_Smed_v6_7219_0_1, [RH, Score=129, Expect=1e-31]} {RNA1509_34033} {RNA1310_18300.1} {RNA815_35699} |
5. | MligTC455_39978 | 270 | 5.62 | Mlig455_052261, Mlig455_052349 | Neo: - Age: Down-Up-Up Region-enriched R8: 3.650/0.00368 |
0.971 | - | - | - | - | - | 0.971 | Mlig455_052261 {REF} {Length: 760} {RNA1310_41850} {RNA815_20313} Mlig455_052349 {REF} {Length: 710} {RNA1310_41850} {RNA815_20313} |
|
6. | MligTC455_21050 | 18 | 0.37 | Mlig455_024510 | Neo: - Age: - |
0.97 | - | - | - | - | - | 0.970 | Mlig455_024510 {REF} {Length: 2499} {RNA1310_68107} {RNA815_59638} | |
7. | MligTC455_18514 | 86 | 1.8 | Mlig455_043176 | Neo: - Age: - |
CALM2 | 0.963 | - | - | - | - | - | 0.963 | Mlig455_043176 {REF} {Length: 1325} {Pfam: EF hand [PF00036.34, score=110.1]; EF-hand domain pair [PF13499.8, score=108.2]; EF-hand domain [PF13405.8, score=88.2]; EF-hand domain pair [PF13833.8, score=85.7]; EF hand [PF13202.8, score=85.5]; EF-hand domain [PF14658.8, score=46.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=34.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=30.0]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=183, Expect=2e-58]; ENSG00000160014, CALM3, calmodulin 3, [Score=182, Expect=9e-59]; ENSG00000198668, CALM1, calmodulin 1, [Score=182, Expect=9e-59]; ENSG00000178363, CALML3, calmodulin like 3, [Score=177, Expect=6e-57]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=184, Expect=6e-59]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=182, Expect=6e-59]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=182, Expect=6e-59]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=181, Expect=2e-58]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=181, Expect=2e-58]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=180, Expect=3e-58]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=180, Expect=2e-58]} {RNA1509_20574} {RNA1310_23382} {RNA815_12969} |
8. | MligTC455_48659 | 72 | 1.51 | Mlig455_038733 | Neo: - Age: - |
BMP1 | 0.955 | - | - | - | - | - | 0.955 | Mlig455_038733 {REF} {Length: 2559} {Pfam: CUB domain [PF00431.22, score=55.5]; CD20-like family [PF04103.17, score=19.6]} {Human: ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=73.6, Expect=7e-13]} {Mouse: ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=73.9, Expect=3e-13]} {Dmel: FBgn0004885, tok, tolkin, [Score=59.3, Expect=8e-09]} {Celegans: WBGene00003555, nas-39, Zinc metalloproteinase nas-39, [Score=59.3, Expect=6e-09]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=62.8, Expect=5e-10]} {RNA1509_45794} {RNA1310_15908} {RNA815_14641.1} |
9. | MligTC455_12359 | 34 | 0.71 | Mlig455_036860, Mlig455_053000 | Neo: - Age: - |
0.953 | - | - | - | - | 0.953 | - | Mlig455_036860 {REF} {Length: 2052} {Pfam: Ammonium Transporter Family [PF00909.23, score=351.9]} {Dmel: FBgn0038309, Amt, Ammonium transporter, [Score=177, Expect=1e-48]} {Celegans: WBGene00000136, amt-4, Ammonium transporter, [Score=361, Expect=7e-119]} {RNA1310_63464} {RNA815_52017} Mlig455_053000 {REF} {Length: 2052} {Pfam: Ammonium Transporter Family [PF00909.23, score=351.9]} {Dmel: FBgn0038309, Amt, Ammonium transporter, [Score=177, Expect=1e-48]} {Celegans: WBGene00000136, amt-4, Ammonium transporter, [Score=361, Expect=7e-119]} {RNA1310_63464} {RNA815_52017} |
|
10. | MligTC455_41126 | 619 | 12.9 | Mlig455_050185 | Neo: - Age: - Region-enriched R6: 3.273/0.00035 |
0.953 | - | - | - | - | 0.953 | - | Mlig455_050185 {REF} {Length: 671} {RNA1509_36640} {RNA1310_51392} {RNA815_51264} | |
11. | MligTC455_11780 | 35 | 0.73 | Mlig455_023335 | Neo: - Age: Down-Up-Down Regeneration-enriched R4: 10.634 |
PDE9A | 0.951 | - | - | - | - | 0.951 | - | Mlig455_023335 {REF} {Length: 3554} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=286.3]} {Human: ENSG00000160191, PDE9A, phosphodiesterase 9A, [Score=544, Expect=0.0]} {Mouse: ENSMUSG00000041119, Pde9a, phosphodiesterase 9A, [Score=549, Expect=0.0]} {Dmel: FBgn0259171, Pde9, Phosphodiesterase 9, [Score=311, Expect=8e-92]} {Celegans: WBGene00020114, pde-4, Probable 3',5'-cyclic phosphodiesterase pde-4, [Score=163, Expect=4e-43]} {Smed: dd_Smed_v6_13304_0_1, dd_Smed_v6_13304_0_1, [Score=298, Expect=3e-93]} {RNA1310_14570} {RNA815_20478} |