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Results for MligTC455_22200

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_22200 764 15.92 Mlig455_018539

Neo: Germline

Age: Up-Down-Up, logFC(26M/2M)=0.330

Region-enriched R4: 2.959/0.00000
Region-enriched R3: 2.286/0.00001

 Mlig455_018539 {REF} {Length: 876} {Pfam: HD domain [PF01966.24, score=24.2]} {RNA1509_10650} {RNA1310_34853.2, RNA1509_10650} {RNA1509_10650, RNA815_15543}

Cumulative graph for MligTC455_22200

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.881 4.317 0.03052 0.44703
RegionR2 -2.023 4.317 0.00424 0.05787
RegionR3 2.286 4.317 0.00000 0.00001
RegionR4 2.959 4.317 0.00000 0.00000
RegionR5 -0.596 4.317 0.25834 0.57815
RegionR6 -1.142 4.317 0.05995 0.45981
RegionR7 -0.651 4.317 0.36186 0.99764
RegionR8 -2.715 4.317 0.01565 0.24366

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.791 4.317 0.12899 0.86144
RegenerationR2 -0.155 4.317 0.82844 0.99705
RegenerationR3 -0.037 4.317 0.94282 1.00000
RegenerationR4 -1.143 4.317 0.03225 0.29040
RegenerationR5 -0.376 4.317 0.51755 0.86820
RegenerationR6 -0.451 4.317 0.52632 0.82450
RegenerationBL -1.154 4.317 0.31397 0.68009
RegenerationTP 0.006 4.317 0.99264 1.00000


Genes with expression patterns similar to MligTC455_22200

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_22200 764 15.92 Mlig455_018539

Neo: Germline

Age: Up-Down-Up, logFC(26M/2M)=0.330

Region-enriched R4: 2.959/0.00000
Region-enriched R3: 2.286/0.00001

 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_018539 {REF} {Length: 876} {Pfam: HD domain [PF01966.24, score=24.2]} {RNA1509_10650} {RNA1310_34853.2, RNA1509_10650} {RNA1509_10650, RNA815_15543}
2. MligTC455_40545 1143 23.82 Mlig455_055297

Neo: -

Age: Down-Down-Up

Region-enriched R3: 3.033/0.00012

 4.219 0.953 - 0.724 0.910 0.714 0.918 Mlig455_055297 {REF} {Length: 1850} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=40.2]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=38.9]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=22.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=21.3]; FAD binding domain [PF01494.21, score=19.7]} {RNA1509_13298, RNA1509_15869} {RNA1310_17901, RNA1509_15869} {RNA1509_15869, RNA815_2201}
3. MligTC455_33611 478 9.95 Mlig455_034367

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=1.080

Region-enriched R4: 2.761/0.00774
Region-enriched R3: 2.079/0.04141

 ASAH2 4.197 0.879 0.789 - 0.961 0.744 0.824 Mlig455_034367 {REF} {Length: 2561} {Pfam: Neutral/alkaline non-lysosomal ceramidase, N-terminal [PF04734.15, score=706.1]; Neutral/alkaline non-lysosomal ceramidase, C-terminal [PF17048.7, score=154.5]} {Human: ENSG00000188611, ASAH2, N-acylsphingosine amidohydrolase 2, [RH, Score=627, Expect=0.0]} {Mouse: ENSMUSG00000024887, Asah2, N-acylsphingosine amidohydrolase 2, [RH, Score=614, Expect=0.0]} {Dmel: FBgn0039774, CDase, Ceramidase, [RH, Score=597, Expect=0.0]} {Smed: dd_Smed_v6_1726_0_1, dd_Smed_v6_1726_0_1, [RH, Score=662, Expect=0.0]} {RNA1509_4146} {RNA1310_8395.1} {RNA815_2759}
4. MligTC455_33610 363 7.57 Mlig455_017447

Neo: Germline

Age: Up-Down-Up, logFC(26M/2M)=2.665

Region-enriched R4: 3.381/0.00901

 ASAH2 3.63 0.942 0.952 - 0.932 - 0.804 Mlig455_017447 {REF} {Length: 2857} {Pfam: Neutral/alkaline non-lysosomal ceramidase, N-terminal [PF04734.15, score=705.2]; Neutral/alkaline non-lysosomal ceramidase, C-terminal [PF17048.7, score=155.5]} {Human: ENSG00000188611, ASAH2, N-acylsphingosine amidohydrolase 2, [RH, Score=628, Expect=0.0]} {Mouse: ENSMUSG00000024887, Asah2, N-acylsphingosine amidohydrolase 2, [RH, Score=613, Expect=0.0]} {Dmel: FBgn0039774, CDase, Ceramidase, [RH, Score=594, Expect=0.0]} {Smed: dd_Smed_v6_1726_0_1, dd_Smed_v6_1726_0_1, [RH, Score=664, Expect=0.0]} {RNA1509_17200} {RNA1310_8395.1} {RNA815_2759}
5. MligTC455_20084 569 11.85 Mlig455_034786

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.575

Region-enriched R3: 2.972/0.00007
Region-enriched R4: 2.323/0.01179

 DNASE1L2 3.553 0.830 - - 0.960 0.834 0.929 Mlig455_034786 {REF} {Length: 1822} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=38.1]} {Human: ENSG00000167968, DNASE1L2, deoxyribonuclease 1 like 2, [RH, Score=185, Expect=8e-55]; ENSG00000163687, DNASE1L3, deoxyribonuclease 1 like 3, [RH, Score=185, Expect=2e-54]; ENSG00000213918, DNASE1, deoxyribonuclease 1, [RH, Score=181, Expect=2e-53]} {Mouse: ENSMUSG00000025279, Dnase1l3, deoxyribonuclease 1-like 3, [RH, Score=184, Expect=3e-54]; ENSMUSG00000024136, Dnase1l2, deoxyribonuclease 1-like 2, [RH, Score=180, Expect=4e-53]; ENSMUSG00000005980, Dnase1, deoxyribonuclease I, [RH, Score=178, Expect=3e-52]} {RNA1509_8194} {RNA1310_18116, RNA1509_8194} {RNA1509_8194, RNA815_13867}
6. MligTC455_53287 6775 141.16 Mlig455_026427, Mlig455_026458, Mlig455_044750

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=2.125

Region-enriched R3: 3.677/0.00000

 3.552 - - 0.792 0.965 0.863 0.932

Mlig455_026427 {REF} {Length: 1166} {RNA1509_15587} {RNA1310_35864} {RNA815_17135}

Mlig455_026458 {REF} {Length: 978} {RNA1509_1133, RNA1509_15587} {RNA1310_35864, RNA1509_1133, RNA1509_15587} {RNA1509_1133, RNA1509_15587, RNA815_17135}

Mlig455_044750 {REF} {Length: 1007} {RNA1509_1133} {RNA1310_35864} {RNA815_17135}
7. MligTC455_07171 232 4.83 Mlig455_025656

Neo: -

Age: Up-Down-Down

Region-specific R4: 4.734

Region-enriched R3: 2.507/0.01222

 ASAH2 2.812 0.959 0.910 - - - 0.943 Mlig455_025656 {REF} {Length: 4314} {TRANSSPLICED} {Pfam: Neutral/alkaline non-lysosomal ceramidase, N-terminal [PF04734.15, score=714.2]; Neutral/alkaline non-lysosomal ceramidase, C-terminal [PF17048.7, score=154.8]} {Human: ENSG00000188611, ASAH2, N-acylsphingosine amidohydrolase 2, [RH, Score=602, Expect=0.0]} {Mouse: ENSMUSG00000024887, Asah2, N-acylsphingosine amidohydrolase 2, [RH, Score=615, Expect=0.0]} {Dmel: FBgn0039774, CDase, Ceramidase, [RH, Score=602, Expect=0.0]} {Smed: dd_Smed_v6_1726_0_1, dd_Smed_v6_1726_0_1, [RH, Score=676, Expect=0.0]} {RNA1509_10573, RNA1509_11988, RNA1509_19979, RNA1509_3145} {RNA1310_6552, RNA1509_10573, RNA1509_11988, RNA1509_19979, RNA1509_3145} {RNA1509_10573, RNA1509_11988, RNA1509_19979, RNA1509_3145, RNA815_1566.1}
8. MligTC455_15093 112 2.34 Mlig455_041676

Neo: -

Age: -

Region-enriched R3: 3.670/0.00011
Region-enriched R4: 3.458/0.00518

 2.802 - - - 0.966 0.949 0.887 Mlig455_041676 {REF} {Length: 286} {NoTransDecoderORF} {RNA1509_45649} {RNA1310_103992} {RNA815_10967.1}
9. MligTC455_26184 7464 155.49 Mlig455_021322

Neo: Germline

Age: -

Region-enriched R3: 2.553/0.00001
Region-enriched R4: 1.898/0.00795

 2.765 0.831 - - - 0.977 0.957 Mlig455_021322 {REF} {Length: 496} {TRANSSPLICED} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=31.0]} {RNA1509_2946, RNA1509_56087, RNA1509_7601} {RNA1310_20339, RNA1509_2946, RNA1509_56087, RNA1509_7601} {RNA1509_2946, RNA1509_56087, RNA1509_7601, RNA815_31444.2}
10. MligTC455_15094 117 2.45 Mlig455_041675

Neo: -

Age: -

Region-enriched R4: 3.891/0.00174
Region-enriched R3: 3.545/0.00033

 2.747 - - - 0.886 0.951 0.910 Mlig455_041675 {REF} {Length: 214} {NoTransDecoderORF} {RNA1509_34671} {RNA1310_22958} {RNA815_52664}
11. MligTC455_46997 1302 27.12 Mlig455_018324

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.900

Region-enriched R4: 3.072/0.00026
Region-enriched R3: 2.531/0.00058
Region-enriched R5: 1.786/0.01855

 CPA2 2.734 - - - 0.893 0.878 0.963 Mlig455_018324 {REF} {Length: 1747} {Pfam: Zinc carboxypeptidase [PF00246.26, score=269.1]; Carboxypeptidase activation peptide [PF02244.18, score=54.2]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2, [RH, Score=287, Expect=3e-93]} {Mouse: ENSMUSG00000071553, Cpa2, carboxypeptidase A2, pancreatic, [RH, Score=288, Expect=2e-93]} {Dmel: FBgn0029807, CG3108, [RH, Score=266, Expect=8e-80]} {Celegans: WBGene00008521, F02D8.4, [RH, Score=251, Expect=3e-79]} {Smed: dd_Smed_v6_5999_0_1, dd_Smed_v6_5999_0_1, [RH, Score=254, Expect=1e-80]} {RNA1509_11873, RNA1509_20365} {RNA1310_21434, RNA1509_11873, RNA1509_20365} {RNA1509_11873, RNA1509_20365, RNA815_8679}
12. MligTC455_36181 465 9.68 Mlig455_066565

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=1.101

Region-enriched R3: 2.467/0.01877

 PLB1 2.716 0.803 - - 0.960 - 0.953 Mlig455_066565 {REF} {Length: 2233} {Pfam: GDSL-like Lipase/Acylhydrolase [PF00657.24, score=77.7]; GDSL-like Lipase/Acylhydrolase family [PF13472.8, score=39.7]} {Human: ENSG00000163803, PLB1, phospholipase B1, [RH, Score=291, Expect=1e-87]} {Mouse: ENSMUSG00000029134, Plb1, phospholipase B1, [RH, Score=308, Expect=1e-93]} {Dmel: FBgn0036939, CG7365, [Score=236, Expect=2e-73]} {Celegans: WBGene00022256, Y73B6BL.37, [RH, Score=244, Expect=4e-77]} {Smed: dd_Smed_v6_2690_0_1, dd_Smed_v6_2690_0_1, [Score=230, Expect=2e-71]} {RNA1509_30374} {RNA1310_16463} {RNA815_8760}
13. MligTC455_20836 544 11.33 Mlig455_001995, Mlig455_002089

Neo: -

Age: logFC(26M/2M)=0.511

Region-enriched R3: 2.686/0.00093
Region-enriched R4: 2.680/0.00402

 HSD17B14 2.712 - - - 0.964 0.859 0.889

Mlig455_001995 {REF} {Length: 929} {Pfam: Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=156.4]; short chain dehydrogenase [PF00106.27, score=155.7]; KR domain [PF08659.12, score=30.6]; Fungal family of unknown function (DUF1776) [PF08643.12, score=19.3]} {Human: ENSG00000087076, HSD17B14, hydroxysteroid 17-beta dehydrogenase 14, [RH, Score=167, Expect=2e-50]} {Mouse: ENSMUSG00000030825, Hsd17b14, hydroxysteroid (17-beta) dehydrogenase 14, [RH, Score=190, Expect=2e-59]} {Dmel: FBgn0051549, CG31549, [Score=109, Expect=2e-28]} {Celegans: WBGene00021647, Y47G6A.22, [Score=100, Expect=4e-25]} {Smed: dd_Smed_v6_2290_0_1, dd_Smed_v6_2290_0_1, [RH, Score=172, Expect=1e-52]} {RNA1509_37621} {RNA1310_34277} {RNA815_18656}

Mlig455_002089 {REF} {Length: 1925} {Pfam: short chain dehydrogenase [PF00106.27, score=157.6]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=157.0]; KR domain [PF08659.12, score=32.3]; Fungal family of unknown function (DUF1776) [PF08643.12, score=18.3]} {Human: ENSG00000087076, HSD17B14, hydroxysteroid 17-beta dehydrogenase 14, [RH, Score=166, Expect=9e-50]} {Mouse: ENSMUSG00000030825, Hsd17b14, hydroxysteroid (17-beta) dehydrogenase 14, [RH, Score=190, Expect=2e-59]} {Dmel: FBgn0037354, CG12171, [Score=112, Expect=1e-29]} {Celegans: WBGene00021647, Y47G6A.22, [Score=97.4, Expect=6e-24]} {Smed: dd_Smed_v6_2290_0_1, dd_Smed_v6_2290_0_1, [RH, Score=173, Expect=5e-53]} {RNA1509_37621, RNA1509_52030} {RNA1310_34277, RNA1509_37621, RNA1509_52030} {RNA1509_37621, RNA1509_52030, RNA815_18656}
14. MligTC455_42921 2549 53.1 Mlig455_026303, Mlig455_026319

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.315

Region-enriched R3: 3.759/0.00000
Region-enriched R4: 1.949/0.01034

 2.679 - - - 0.975 0.775 0.929

Mlig455_026303 {REF} {Length: 811} {Pfam: Group 7 allergen [PF16984.7, score=52.6]} {RNA1509_4404} {RNA1310_17894} {RNA815_9024}

Mlig455_026319 {REF} {Length: 1051} {Pfam: Group 7 allergen [PF16984.7, score=52.6]} {RNA1509_4404} {RNA1310_17894} {RNA815_9024}
15. MligTC455_31631 977 20.36 Mlig455_038575

Neo: -

Age: -

Region-enriched R3: 3.163/0.00000
Region-enriched R4: 1.482/0.02038

 2.66 - - - 0.984 0.749 0.927 Mlig455_038575 {REF} {Length: 1498} {Smed: dd_Smed_v6_279_0_1, dd_Smed_v6_279_0_1, [RH, Score=178, Expect=6e-51]} {RNA1509_14693, RNA1509_21145} {RNA1310_23343, RNA1509_14693} {RNA1509_14693, RNA815_10091}
16. MligTC455_31630 2484 51.74 Mlig455_037320, Mlig455_038438

Neo: -

Age: -

Region-enriched R3: 3.308/0.00000
Region-enriched R4: 1.531/0.00804

 2.631 - - - 0.990 0.782 0.859

Mlig455_037320 {REF} {Length: 1821} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=24.2]} {RNA1509_36985} {RNA1310_21834.1} {RNA815_12605}

Mlig455_038438 {REF} {Length: 2747} {Smed: dd_Smed_v6_279_0_1, dd_Smed_v6_279_0_1, [RH, Score=177, Expect=3e-49]} {RNA1509_21145} {RNA1310_23343} {RNA815_10091}
17. MligTC455_28305 151 3.15 Mlig455_068805

Neo: Irradiation

Age: Up-Down-Down

 2.592 0.788 0.820 - 0.984 - - Mlig455_068805 {REF} {Length: 3071} {RNA1509_36682, RNA1509_51681} {RNA1310_928.1, RNA1509_36682} {RNA1509_36682, RNA815_529.1}
18. MligTC455_27242 14489 301.86 Mlig455_056957

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.849

Region-enriched R3: 2.848/0.00000
Region-enriched R5: 1.349/0.04924

 GM2A 2.57 - - - 0.779 0.841 0.950 Mlig455_056957 {REF} {Length: 877} {Pfam: ML domain [PF02221.17, score=41.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=51.6, Expect=7e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=50.8, Expect=1e-07]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=56.2, Expect=3e-10]} {RNA1509_960} {RNA1310_28835.1} {RNA815_6681.1}
19. MligTC455_11766 201 4.18 Mlig455_048732

Neo: -

Age: -

Region-enriched R3: 3.689/0.00006

 2.559 - - - 0.990 0.801 0.768 Mlig455_048732 {REF} {Length: 376} {NoTransDecoderORF} {RNA1310_75754} {RNA815_50709.2}
20. MligTC455_18469 533 11.11 Mlig455_070391

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.656

 2.552 0.726 - - - 0.872 0.954 Mlig455_070391 {REF} {Length: 1452} {Pfam: Lipase (class 3) [PF01764.27, score=96.6]} {Celegans: WBGene00022457, Y110A7A.7, [Score=157, Expect=1e-44]} {RNA1509_36256, RNA1509_36380} {RNA1310_22408, RNA1509_36380} {RNA1509_36380, RNA815_9975}
21. MligTC455_15008 345 7.19 Mlig455_069659

Neo: -

Age: -

Region-enriched R3: 6.285/0.00000
Region-enriched R4: 2.829/0.04013

 2.549 - - - 0.991 0.827 0.731 Mlig455_069659 {REF} {Length: 394} {NoTransDecoderORF} {RNA1310_75754} {RNA815_50709.2}
22. MligTC455_27244 10289 214.35 Mlig455_067857

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.836

Region-enriched R3: 3.075/0.00000
Region-enriched R4: 2.397/0.00006
Region-enriched R5: 1.397/0.01351

 GM2A 2.546 - - - 0.805 0.788 0.953 Mlig455_067857 {REF} {Length: 878} {Pfam: ML domain [PF02221.17, score=40.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=51.6, Expect=8e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=50.8, Expect=1e-07]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=56.2, Expect=4e-10]} {RNA1509_23026, RNA1509_960} {RNA1310_28835.1, RNA1509_23026} {RNA1509_23026, RNA815_6681.1}
23. MligTC455_34409 4786 99.71 Mlig455_051480

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.974

Region-specific R3: 4.094

Region-enriched R3: 3.637/0.00000
Region-enriched R4: 1.849/0.00051
Region-enriched R5: 1.030/0.03456

Regeneration-enriched R2: 2.672
Regeneration-enriched TP: 2.301

 2.544 - - - 0.963 0.735 0.846 Mlig455_051480 {REF} {Length: 1610} {Pfam: Ependymin [PF00811.20, score=69.8]} {RNA1509_1990} {RNA1310_23428.1, RNA1509_1990} {RNA1509_1990, RNA815_9917}
24. MligTC455_22527 180 3.75 Mlig455_016486

Neo: -

Age: logFC(26M/2M)=3.591

Region-enriched R3: 4.421/0.00282

 2.473 - - - 0.963 0.774 0.736 Mlig455_016486 {REF} {Length: 1533} {TRANSSPLICED} {Pfam: Haemolymph juvenile hormone binding protein (JHBP) [PF06585.13, score=150.8]} {Dmel: FBgn0038395, CG10407, [RH, Score=86.7, Expect=5e-19]} {Smed: dd_Smed_v6_888_0_1, dd_Smed_v6_888_0_1, [Score=90.1, Expect=2e-20]} {RNA1509_13349} {RNA1310_21535.1} {RNA815_6279.1}
25. MligTC455_52857 637 13.26 Mlig455_043603

Neo: -

Age: Down-Down-Up

Region-enriched R3: 3.322/0.00004
Region-enriched R4: 2.417/0.01029
Region-enriched R5: 1.980/0.01997

 MCFD2 2.441 - - - 0.768 0.707 0.966 Mlig455_043603 {REF} {Length: 763} {Pfam: EF-hand domain pair [PF13499.8, score=40.4]; EF-hand domain [PF13405.8, score=36.0]; EF hand [PF00036.34, score=35.7]; EF-hand domain pair [PF13833.8, score=25.8]} {Human: ENSG00000180398, MCFD2, multiple coagulation factor deficiency 2, [Score=61.6, Expect=6e-12]} {Mouse: ENSMUSG00000024150, Mcfd2, multiple coagulation factor deficiency 2, [Score=59.7, Expect=2e-11]} {Dmel: FBgn0037798, CG12817, [RH, Score=53.5, Expect=5e-09]} {Celegans: WBGene00010075, F55A11.1, [RH, Score=70.1, Expect=4e-15]} {RNA1509_17013} {RNA1310_37099} {RNA815_18915}
26. MligTC455_41071 595 12.4 Mlig455_050924

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.124

Region-specific R3: 6.335

Region-enriched R3: 6.230/0.00000
Region-enriched R4: 3.678/0.00128

 1.887 - - - 0.985 - 0.902 Mlig455_050924 {REF} {Length: 782} {RNA1509_24397, RNA1509_40835} {RNA1310_44283.1, RNA1509_24397, RNA1509_40835} {RNA1509_24397, RNA1509_40835, RNA815_21735}
27. MligTC455_07170 666 13.88 Mlig455_025202

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.753/0.00051

 ASAH2 1.872 0.950 0.922 - - - - Mlig455_025202 {REF} {Length: 2383} {Pfam: Neutral/alkaline non-lysosomal ceramidase, N-terminal [PF04734.15, score=251.6]; Neutral/alkaline non-lysosomal ceramidase, C-terminal [PF17048.7, score=156.6]} {Human: ENSG00000188611, ASAH2, N-acylsphingosine amidohydrolase 2, [Score=304, Expect=3e-96]} {Mouse: ENSMUSG00000024887, Asah2, N-acylsphingosine amidohydrolase 2, [Score=308, Expect=2e-98]} {Dmel: FBgn0039774, CDase, Ceramidase, [Score=315, Expect=1e-101]} {Smed: dd_Smed_v6_1726_0_1, dd_Smed_v6_1726_0_1, [Score=316, Expect=5e-102]} {RNA1509_11988, RNA1509_57863} {RNA1310_19808, RNA1509_57863} {RNA1509_57863, RNA815_1566.1}
28. MligTC455_52855 748 15.59 Mlig455_029551, Mlig455_040460

Neo: -

Age: -

Region-enriched R3: 5.112/0.00000
Region-enriched R4: 3.658/0.00041
Region-enriched R5: 3.118/0.00161

 MCFD2 1.867 - - - 0.917 - 0.950

Mlig455_029551 {REF} {Length: 937} {Pfam: EF-hand domain pair [PF13499.8, score=45.6]; EF-hand domain [PF13405.8, score=36.2]; EF hand [PF00036.34, score=36.1]; EF-hand domain pair [PF13833.8, score=25.7]} {Human: ENSG00000180398, MCFD2, multiple coagulation factor deficiency 2, [Score=62.0, Expect=5e-12]} {Mouse: ENSMUSG00000024150, Mcfd2, multiple coagulation factor deficiency 2, [Score=60.1, Expect=2e-11]} {Dmel: FBgn0037798, CG12817, [RH, Score=53.5, Expect=6e-09]} {Celegans: WBGene00010075, F55A11.1, [RH, Score=70.1, Expect=3e-15]} {RNA1509_28625} {RNA1310_37099} {RNA815_18915}

Mlig455_040460 {REF} {Length: 1066} {Pfam: EF-hand domain pair [PF13499.8, score=41.5]; EF hand [PF00036.34, score=36.3]; EF-hand domain [PF13405.8, score=36.3]; EF-hand domain pair [PF13833.8, score=25.9]} {Human: ENSG00000180398, MCFD2, multiple coagulation factor deficiency 2, [Score=61.6, Expect=6e-12]} {Mouse: ENSMUSG00000024150, Mcfd2, multiple coagulation factor deficiency 2, [Score=60.1, Expect=1e-11]} {Dmel: FBgn0037798, CG12817, [RH, Score=53.5, Expect=4e-09]} {Celegans: WBGene00010075, F55A11.1, [RH, Score=70.1, Expect=2e-15]} {RNA1509_11624, RNA1509_17013, RNA1509_28625} {RNA1310_37099, RNA1509_11624, RNA1509_17013, RNA1509_28625} {RNA1509_11624, RNA1509_17013, RNA1509_28625, RNA815_18915}
29. MligTC455_43194 11396 237.42 Mlig455_009763, Mlig455_070122

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.399/0.00716

 CST3 1.832 - - - - 0.879 0.953

Mlig455_009763 {REF} {Length: 720} {Pfam: Cystatin domain [PF00031.23, score=28.8]} {Human: ENSG00000101439, CST3, cystatin C, [RH, Score=44.7, Expect=6e-06]} {RNA1509_26463, RNA1509_2883, RNA1509_6502} {RNA1310_51190, RNA1509_2883, RNA1509_6502} {RNA1509_2883, RNA1509_6502, RNA815_25269}

Mlig455_070122 {REF} {Length: 736} {Pfam: Cystatin domain [PF00031.23, score=28.8]} {Human: ENSG00000101439, CST3, cystatin C, [RH, Score=44.7, Expect=6e-06]} {RNA1509_26463, RNA1509_4516, RNA1509_5046, RNA1509_7022} {RNA1310_51190, RNA1509_26463, RNA1509_4516, RNA1509_5046, RNA1509_7022} {RNA1509_26463, RNA1509_4516, RNA1509_5046, RNA1509_7022, RNA815_25269}
30. MligTC455_51131 5808 120.99 Mlig455_031629

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.484

Region-enriched R3: 3.757/0.00000
Region-enriched R4: 2.189/0.01454

 1.815 - - - - 0.850 0.965 Mlig455_031629 {REF} {Length: 1657} {Pfam: Glycosyl hydrolases family 16 [PF00722.23, score=60.4]} {Dmel: FBgn0040323, GNBP1, Gram-negative bacteria binding protein 1, [RH, Score=160, Expect=4e-44]} {RNA1509_304} {RNA1310_18175.2} {RNA815_10892.1}
31. MligTC455_18468 49 1.02 Mlig455_014453

Neo: -

Age: -

Region-enriched R4: 3.552/0.03158

 1.813 - - - - 0.856 0.957 Mlig455_014453 {REF} {Length: 1446} {Pfam: Lipase (class 3) [PF01764.27, score=96.6]} {Celegans: WBGene00022457, Y110A7A.7, [Score=158, Expect=6e-45]} {RNA1509_36256} {RNA1310_22408} {RNA815_9975}
32. MligTC455_12956 260 5.41 Mlig455_013752

Neo: -

Age: logFC(26M/2M)=3.929

Region-enriched R3: 5.406/0.00000
Region-enriched R4: 3.999/0.00332

 TLL1 1.805 - - - 0.965 - 0.840 Mlig455_013752 {REF} {Length: 1191} {Pfam: Astacin (Peptidase family M12A) [PF01400.26, score=173.5]} {Human: ENSG00000038295, TLL1, tolloid like 1, [Score=127, Expect=5e-34]; ENSG00000095587, TLL2, tolloid like 2, [Score=121, Expect=8e-31]} {Mouse: ENSMUSG00000053626, Tll1, tolloid-like, [Score=126, Expect=9e-33]; ENSMUSG00000025013, Tll2, tolloid-like 2, [Score=123, Expect=2e-31]} {Dmel: FBgn0028949, CG15254, [RH, Score=162, Expect=4e-49]} {Celegans: WBGene00003533, nas-14, Zinc metalloproteinase nas-14, [RH, Score=126, Expect=2e-33]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=106, Expect=3e-26]} {RNA1509_11696, RNA1509_13473, RNA1509_31566} {RNA1310_38053, RNA1509_11696, RNA1509_13473, RNA1509_31566} {RNA1509_11696, RNA1509_13473, RNA1509_31566, RNA815_18366.1}
33. MligTC455_41072 794 16.55 Mlig455_050940

Neo: -

Age: logFC(26M/2M)=1.072

Region-specific R3: 4.616

Region-enriched R3: 4.925/0.00000

 1.805 - - - 0.959 - 0.846 Mlig455_050940 {REF} {Length: 769} {RNA1509_10741, RNA1509_26937} {RNA1310_44283.1, RNA1509_10741, RNA1509_26937} {RNA1509_10741, RNA1509_26937, RNA815_21735}
34. MligTC455_15448 1109 23.1 Mlig455_051485

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=2.807

Region-enriched R3: 5.610/0.00000
Region-enriched R4: 4.154/0.00029

 MEP1B 1.78 - - - 0.961 - 0.819 Mlig455_051485 {REF} {Length: 966} {Pfam: Astacin (Peptidase family M12A) [PF01400.26, score=152.5]} {Human: ENSG00000141434, MEP1B, meprin A subunit beta, [Score=105, Expect=3e-25]; ENSG00000188886, ASTL, astacin like metalloendopeptidase, [Score=100, Expect=7e-24]} {Mouse: ENSMUSG00000024313, Mep1b, meprin 1 beta, [Score=104, Expect=4e-25]; ENSMUSG00000023914, Mep1a, meprin 1 alpha, [Score=102, Expect=2e-24]; ENSMUSG00000053626, Tll1, tolloid-like, [Score=99.4, Expect=2e-23]} {Dmel: FBgn0028949, CG15254, [Score=119, Expect=3e-32]} {Celegans: WBGene00003523, nas-4, Zinc metalloproteinase nas-4, [Score=119, Expect=4e-32]} {Smed: dd_Smed_v6_51_1_2, dd_Smed_v6_51_1_2, [RH, Score=148, Expect=7e-44]} {RNA1509_16597, RNA1509_2724} {RNA1310_37686, RNA1509_16597, RNA1509_2724} {RNA1509_16597, RNA1509_2724, RNA815_17836}
35. MligTC455_44707 2674 55.7 Mlig455_060882

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=3.903

Region-enriched R3: 5.097/0.00000

 TLL1 1.743 - - - 0.967 - 0.776 Mlig455_060882 {REF} {Length: 934} {Pfam: Astacin (Peptidase family M12A) [PF01400.26, score=170.1]} {Human: ENSG00000038295, TLL1, tolloid like 1, [Score=118, Expect=9e-31]; ENSG00000188886, ASTL, astacin like metalloendopeptidase, [Score=117, Expect=5e-30]; ENSG00000141434, MEP1B, meprin A subunit beta, [Score=115, Expect=1e-28]; ENSG00000168487, BMP1, bone morphogenetic protein 1, [Score=114, Expect=1e-28]} {Mouse: ENSMUSG00000053626, Tll1, tolloid-like, [Score=119, Expect=3e-30]; ENSMUSG00000024313, Mep1b, meprin 1 beta, [Score=117, Expect=1e-29]; ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [Score=114, Expect=1e-28]} {Dmel: FBgn0028948, CG15253, [RH, Score=152, Expect=2e-45]} {Celegans: WBGene00003523, nas-4, Zinc metalloproteinase nas-4, [Score=129, Expect=5e-36]} {Smed: dd_Smed_v6_961_0_1, dd_Smed_v6_961_0_1, [Score=109, Expect=4e-29]} {RNA1509_58597} {RNA1310_40274} {RNA815_19279.1}
36. MligTC455_34148 247 5.14 Mlig455_021858

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.517

Region-enriched R3: 3.529/0.00963

 1.735 0.765 - - - - 0.970 Mlig455_021858 {REF} {Length: 16541} {Pfam: FKBP26_C-terminal [PF18046.3, score=39.1]; Galactoside-binding lectin [PF00337.24, score=27.5]} {RNA1509_23521} {RNA1310_3139} {RNA815_6819}
37. MligTC455_44576 827 17.23 Mlig455_035737

Neo: -

Age: Down-Down-Down

Region-enriched R3: 3.810/0.00000
Region-enriched R4: 2.716/0.00215

 NPC2 1.712 0.748 - - - - 0.964 Mlig455_035737 {REF} {Length: 750} {Pfam: ML domain [PF02221.17, score=97.3]} {Human: ENSG00000119655, NPC2, NPC intracellular cholesterol transporter 2, [RH, Score=136, Expect=2e-40]} {Mouse: ENSMUSG00000021242, Npc2, NPC intracellular cholesterol transporter 2, [RH, Score=132, Expect=5e-40]} {Dmel: FBgn0031381, Npc2a, Niemann-Pick type C-2a, [RH, Score=144, Expect=1e-44]} {Smed: dd_Smed_v6_602_0_1, dd_Smed_v6_602_0_1, [RH, Score=139, Expect=6e-43]} {RNA1509_4097, RNA1509_41414} {RNA1310_51205, RNA1509_4097, RNA1509_41414} {RNA1509_4097, RNA1509_41414, RNA815_27598}
38. MligTC455_12757 29 0.61 Mlig455_036078

Neo: -

Age: Down-Down-Up

 0.98 - - - - - 0.980 Mlig455_036078 {REF} {Length: 1242} {RNA1509_5640} {RNA1310_31330} {RNA815_4830.1}
39. MligTC455_48414 91 1.89 Mlig455_066457

Neo: -

Age: Down-Up-Up

 0.979 - - - 0.979 - - Mlig455_066457 {REF} {Length: 551} {TRANSSPLICED} {RNA1509_30785} {RNA1310_66748, RNA1509_30785} {RNA1509_30785, RNA815_26458}
40. MligTC455_24187 34 0.7 Mlig455_009347

Neo: -

Age: -

 GCKR 0.974 - - - - - 0.974 Mlig455_009347 {REF} {Length: 2451} {Human: ENSG00000084734, GCKR, glucokinase regulator, [Score=53.5, Expect=3e-07]} {Mouse: ENSMUSG00000059434, Gckr, glucokinase regulatory protein, [Score=52.0, Expect=7e-07]} {RNA1509_51386} {RNA1310_15402} {RNA815_64810}
41. MligTC455_12335 11 0.23 Mlig455_029701

Neo: -

Age: -

 0.972 - - - 0.972 - - Mlig455_029701 {REF} {Length: 270} {NoTransDecoderORF} {RNA1509_48611} {RNA1310_56143}
42. MligTC455_02917 13 0.26 Mlig455_071074

Neo: -

Age: -

 0.971 - - - 0.971 - - Mlig455_071074 {REF} {Length: 208} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_14869} {RNA1310_70688}
43. MligTC455_48263 55 1.15 Mlig455_069902

Neo: -

Age: -

 0.969 - - - 0.969 - - Mlig455_069902 {REF} {Length: 3330} {TRANSSPLICED} {RNA1509_49883} {RNA1310_18334.3} {RNA815_7372}
44. MligTC455_06672 4 0.09 Mlig455_064788

Neo: -

Age: -

 0.965 - - - 0.965 - - Mlig455_064788 {REF} {Length: 608} {NoTransDecoderORF} {RNA1509_5902} {RNA1310_60443} {RNA815_3484.1}
45. MligTC455_46106 17 0.35 Mlig455_005750

Neo: -

Age: -

 NEUROD1 0.965 - - - 0.965 - - Mlig455_005750 {REF} {Length: 2658} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=57.3]} {Human: ENSG00000162992, NEUROD1, neuronal differentiation 1, [Score=63.9, Expect=1e-10]; ENSG00000123307, NEUROD4, neuronal differentiation 4, [Score=63.2, Expect=2e-10]; ENSG00000181965, NEUROG1, neurogenin 1, [Score=62.8, Expect=1e-10]; ENSG00000146618, FERD3L, Fer3 like bHLH transcription factor, [Score=62.8, Expect=3e-11]; ENSG00000168267, PTF1A, pancreas associated transcription factor 1a, [Score=61.6, Expect=5e-10]; ENSG00000171532, NEUROD2, neuronal differentiation 2, [Score=61.2, Expect=9e-10]; ENSG00000260428, SCX, scleraxis bHLH transcription factor, [Score=60.8, Expect=3e-10]; ENSG00000125878, TCF15, transcription factor 15, [Score=60.8, Expect=3e-10]} {Mouse: ENSMUSG00000048015, Neurod4, neurogenic differentiation 4, [Score=65.1, Expect=3e-11]; ENSMUSG00000068079, Tcf15, transcription factor 15, [Score=64.7, Expect=1e-11]; ENSMUSG00000034701, Neurod1, neurogenic differentiation 1, [Score=63.9, Expect=8e-11]; ENSMUSG00000046518, Ferd3l, Fer3 like bHLH transcription factor, [Score=63.5, Expect=1e-11]; ENSMUSG00000048904, Neurog1, neurogenin 1, [Score=62.8, Expect=8e-11]} {Dmel: FBgn0037475, Fer1, 48 related 1, [Score=70.9, Expect=1e-13]} {Celegans: WBGene00001954, hlh-10, Helix Loop Helix, [RH, Score=57.0, Expect=2e-09]} {Smed: dd_Smed_v6_6869_0_1, dd_Smed_v6_6869_0_1, [RH, Score=68.2, Expect=2e-13]} {RNA1310_27559} {RNA815_55155}
46. MligTC455_30398 332 6.92 Mlig455_029585, Mlig455_029606, Mlig455_061517

Neo: -

Age: -

Region-enriched R4: 5.143/0.00000

 0.963 - - - - - 0.963

Mlig455_029585 {REF} {Length: 1248} {RNA1310_21610.1} {RNA815_16631}

Mlig455_029606 {REF} {Length: 1243} {RNA1310_21610.1} {RNA815_16631}

Mlig455_061517 {REF} {Length: 1435} {RNA1310_21610.1} {RNA815_16631}
47. MligTC455_51488 705 14.69 Mlig455_012553

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.664

Region-enriched R3: 2.668/0.00000
Region-enriched R6: 2.438/0.00009

 0.957 - - - 0.957 - - Mlig455_012553 {REF} {Length: 1481} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=34.4]} {RNA1509_12735, RNA1509_14804, RNA1509_20818} {RNA1310_19974, RNA1509_12735, RNA1509_20818} {RNA1509_12735, RNA1509_20818, RNA815_8492}
48. MligTC455_41954 117 2.44 Mlig455_030295

Neo: -

Age: Up-Down-Up

 0.954 - - - - - 0.954 Mlig455_030295 {REF} {Length: 548} {NoTransDecoderORF} {RNA1509_38678} {RNA1310_19204} {RNA815_26429}
49. MligTC455_14007 86 1.79 Mlig455_025913

Neo: -

Age: -

 0.953 - - - 0.953 - - Mlig455_025913 {REF} {Length: 1361} {RNA1509_45083} {RNA1310_6827.1} {RNA815_12324}
50. MligTC455_30059 146 3.03 Mlig455_037493

Neo: -

Age: Down-Up-Down

 0.953 - - - - - 0.953 Mlig455_037493 {REF} {Length: 1507} {Pfam: EGF-like domain [PF07974.15, score=26.0]} {RNA1509_9418} {RNA1310_2624} {RNA815_768.1}
51. MligTC455_16870 298 6.2 Mlig455_048085

Neo: -

Age: -

 SLCO3A1 0.952 - - - - - 0.952 Mlig455_048085 {REF} {Length: 2716} {Pfam: Organic Anion Transporter Polypeptide (OATP) family [PF03137.22, score=287.0]; Major Facilitator Superfamily [PF07690.18, score=39.0]} {Human: ENSG00000176463, SLCO3A1, solute carrier organic anion transporter family member 3A1, [Score=160, Expect=6e-41]; ENSG00000137571, SLCO5A1, solute carrier organic anion transporter family member 5A1, [Score=156, Expect=3e-39]; ENSG00000084453, SLCO1A2, solute carrier organic anion transporter family member 1A2, [Score=156, Expect=1e-39]; ENSG00000139155, SLCO1C1, solute carrier organic anion transporter family member 1C1, [Score=153, Expect=2e-38]} {Mouse: ENSMUSG00000030237, Slco1a4, solute carrier organic anion transporter family, member 1a4, [Score=163, Expect=4e-42]; ENSMUSG00000063975, Slco1a5, solute carrier organic anion transporter family, member 1a5, [Score=162, Expect=1e-41]; ENSMUSG00000025790, Slco3a1, solute carrier organic anion transporter family, member 3a1, [Score=159, Expect=1e-40]; ENSMUSG00000079262, Slco1a6, solute carrier organic anion transporter family, member 1a6, [Score=159, Expect=6e-41]; ENSMUSG00000030737, Slco2b1, solute carrier organic anion transporter family, member 2b1, [Score=155, Expect=2e-39]} {Dmel: FBgn0036732, Oatp74D, Organic anion transporting polypeptide 74D, [Score=153, Expect=1e-38]} {Celegans: WBGene00009023, F21G4.1, Solute carrier organic anion transporter family member, [Score=160, Expect=1e-41]} {Smed: dd_Smed_v6_3499_0_1, dd_Smed_v6_3499_0_1, [RH, Score=406, Expect=2e-133]} {RNA1509_25721} {RNA1310_8958} {RNA815_2912}
52. MligTC455_16632 28 0.59 Mlig455_046527, Mlig455_046632

Neo: -

Age: -

 0.951 - - - - - 0.951

Mlig455_046527 {REF} {Length: 1506} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=35.7]} {RNA1310_21597.1} {RNA815_9247}

Mlig455_046632 {REF} {Length: 1520} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=35.7]} {RNA1310_21597.1} {RNA815_9247}
53. MligTC455_16869 268 5.59 Mlig455_019667

Neo: -

Age: -

 SLCO3A1 0.95 - - - - - 0.950 Mlig455_019667 {REF} {Length: 2659} {Pfam: Organic Anion Transporter Polypeptide (OATP) family [PF03137.22, score=281.1]; Major Facilitator Superfamily [PF07690.18, score=40.0]} {Human: ENSG00000176463, SLCO3A1, solute carrier organic anion transporter family member 3A1, [Score=164, Expect=3e-42]; ENSG00000137571, SLCO5A1, solute carrier organic anion transporter family member 5A1, [Score=164, Expect=8e-42]; ENSG00000084453, SLCO1A2, solute carrier organic anion transporter family member 1A2, [Score=159, Expect=8e-41]} {Mouse: ENSMUSG00000063975, Slco1a5, solute carrier organic anion transporter family, member 1a5, [Score=166, Expect=3e-43]; ENSMUSG00000030237, Slco1a4, solute carrier organic anion transporter family, member 1a4, [Score=166, Expect=5e-43]; ENSMUSG00000025790, Slco3a1, solute carrier organic anion transporter family, member 3a1, [Score=163, Expect=3e-42]; ENSMUSG00000079262, Slco1a6, solute carrier organic anion transporter family, member 1a6, [Score=161, Expect=1e-41]; ENSMUSG00000025938, Slco5a1, solute carrier organic anion transporter family, member 5A1, [Score=159, Expect=2e-40]} {Dmel: FBgn0036732, Oatp74D, Organic anion transporting polypeptide 74D, [Score=156, Expect=1e-39]} {Celegans: WBGene00009023, F21G4.1, Solute carrier organic anion transporter family member, [Score=164, Expect=6e-43]} {Smed: dd_Smed_v6_3499_0_1, dd_Smed_v6_3499_0_1, [RH, Score=411, Expect=2e-135]} {RNA1509_19760, RNA1509_25721} {RNA1310_8958, RNA1509_19760, RNA1509_25721} {RNA1509_19760, RNA1509_25721, RNA815_2912}
54. MligTC455_23221 236 4.91 Mlig455_003590, Mlig455_015401

Neo: -

Age: -

 0.95 - - - - - 0.950

Mlig455_003590 {REF} {Length: 1425} {Pfam: Siphovirus Gp157 [PF05565.13, score=18.7]} {RNA1509_49661, RNA1509_56563} {RNA1310_25909, RNA1509_49661, RNA1509_56563} {RNA1509_49661, RNA1509_56563, RNA815_10495.2}

Mlig455_015401 {REF} {Length: 2622} {Pfam: Siphovirus Gp157 [PF05565.13, score=18.7]} {RNA1509_49661} {RNA1310_25909} {RNA815_10495.2}

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