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Results for MligTC455_15094

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_15094 117 2.45 Mlig455_041675

Neo: -

Age: -

Region-enriched R4: 3.891/0.00174
Region-enriched R3: 3.545/0.00033

Mlig455_041675 {REF} {Length: 214} {NoTransDecoderORF} {RNA1509_34671} {RNA1310_22958} {RNA815_52664}

Cumulative graph for MligTC455_15094

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 2.891 2.335 0.22637 0.87074
RegionR2 -4.045 2.335 0.99956 1.00000
RegionR3 3.545 2.335 0.00000 0.00033
RegionR4 3.891 2.335 0.00011 0.00174
RegionR5 1.641 2.335 0.03416 0.14229
RegionR6 -0.639 2.335 0.93043 1.00000
RegionR7 -5.295 2.335 0.04373 0.40207
RegionR8 -1.988 2.335 0.99805 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.292 2.335 0.70619 1.00000
RegenerationR2 1.787 2.335 0.22873 0.67652
RegenerationR3 -1.123 2.335 0.16860 0.60273
RegenerationR4 -0.147 2.335 0.85791 1.00000
RegenerationR5 -2.261 2.335 0.01197 0.19324
RegenerationR6 0.195 2.335 0.88071 1.00000
RegenerationBL -1.33 2.335 0.99952 1.00000
RegenerationTP -1.435 2.335 0.99964 1.00000


Genes with expression patterns similar to MligTC455_15094

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_15094 117 2.45 Mlig455_041675

Neo: -

Age: -

Region-enriched R4: 3.891/0.00174
Region-enriched R3: 3.545/0.00033

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_041675 {REF} {Length: 214} {NoTransDecoderORF} {RNA1509_34671} {RNA1310_22958} {RNA815_52664}
2. MligTC455_15093 112 2.34 Mlig455_041676

Neo: -

Age: -

Region-enriched R3: 3.670/0.00011
Region-enriched R4: 3.458/0.00518

5.917 0.998 1.000 1.000 0.930 1.000 0.989 Mlig455_041676 {REF} {Length: 286} {NoTransDecoderORF} {RNA1509_45649} {RNA1310_103992} {RNA815_10967.1}
3. MligTC455_56966 130 2.71 Mlig455_033002

Neo: -

Age: -

Region-enriched R3: 3.605/0.00022
Region-enriched R4: 3.360/0.01021

5.729 0.983 0.987 0.990 0.978 0.828 0.963 Mlig455_033002 {REF} {Length: 78} {NoTransDecoderORF} {RNA1509_7667} {RNA1310_50600} {RNA815_52664}
4. MligTC455_27241 10110 210.63 Mlig455_053246

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=2.221

Region-enriched R3: 3.010/0.00000
Region-enriched R4: 2.258/0.00047
Region-enriched R5: 1.305/0.03280

GM2A 5.273 0.896 0.953 0.727 0.857 0.892 0.948 Mlig455_053246 {REF} {Length: 888} {Pfam: ML domain [PF02221.17, score=40.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=51.6, Expect=8e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=50.8, Expect=1e-07]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=56.2, Expect=4e-10]} {RNA1509_180, RNA1509_30371, RNA1509_960} {RNA1310_28835.1, RNA1509_180, RNA1509_30371, RNA1509_960} {RNA1509_180, RNA1509_30371, RNA1509_960, RNA815_6681.1}
5. MligTC455_27244 10289 214.35 Mlig455_067857

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.836

Region-enriched R3: 3.075/0.00000
Region-enriched R4: 2.397/0.00006
Region-enriched R5: 1.397/0.01351

GM2A 5.214 0.881 0.957 0.708 0.844 0.872 0.952 Mlig455_067857 {REF} {Length: 878} {Pfam: ML domain [PF02221.17, score=40.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=51.6, Expect=8e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=50.8, Expect=1e-07]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=56.2, Expect=4e-10]} {RNA1509_23026, RNA1509_960} {RNA1310_28835.1, RNA1509_23026} {RNA1509_23026, RNA815_6681.1}
6. MligTC455_37228 6330 131.87 Mlig455_000997, Mlig455_000998

Neo: -

Age: -

Region-enriched R3: 3.678/0.00000
Region-enriched R4: 1.956/0.00354
Region-enriched R5: 1.419/0.02021

4.668 0.963 0.874 - 0.922 0.942 0.967

Mlig455_000997 {REF} {Length: 1791} {NoTransDecoderORF} {RNA1509_48140} {RNA1310_37194} {RNA815_10967.1}

Mlig455_000998 {REF} {Length: 1436} {NoTransDecoderORF} {RNA1509_55514} {RNA1310_37194} {RNA815_10967.1}
7. MligTC455_37233 10129 211.02 Mlig455_068685

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.425

Region-enriched R3: 3.026/0.00000

4.585 0.880 0.955 - 0.885 0.960 0.905 Mlig455_068685 {REF} {Length: 1176} {RNA1509_2138, RNA1509_3393, RNA1509_638} {RNA1310_29763.1, RNA1509_2138, RNA1509_3393, RNA1509_638} {RNA1509_2138, RNA1509_3393, RNA1509_638, RNA815_14819.1}
8. MligTC455_20084 569 11.85 Mlig455_034786

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.575

Region-enriched R3: 2.972/0.00007
Region-enriched R4: 2.323/0.01179

DNASE1L2 4.566 0.887 0.842 - 0.968 0.894 0.975 Mlig455_034786 {REF} {Length: 1822} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=38.1]} {Human: ENSG00000167968, DNASE1L2, deoxyribonuclease 1 like 2, [RH, Score=185, Expect=8e-55]; ENSG00000163687, DNASE1L3, deoxyribonuclease 1 like 3, [RH, Score=185, Expect=2e-54]; ENSG00000213918, DNASE1, deoxyribonuclease 1, [RH, Score=181, Expect=2e-53]} {Mouse: ENSMUSG00000025279, Dnase1l3, deoxyribonuclease 1-like 3, [RH, Score=184, Expect=3e-54]; ENSMUSG00000024136, Dnase1l2, deoxyribonuclease 1-like 2, [RH, Score=180, Expect=4e-53]; ENSMUSG00000005980, Dnase1, deoxyribonuclease I, [RH, Score=178, Expect=3e-52]} {RNA1509_8194} {RNA1310_18116, RNA1509_8194} {RNA1509_8194, RNA815_13867}
9. MligTC455_47182 14582 303.8 Mlig455_058015, Mlig455_058180, Mlig455_058206

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.558

Region-enriched R3: 3.886/0.00000
Region-enriched R4: 2.020/0.01181

GM2A 4.559 0.952 0.878 - 0.898 0.849 0.982

Mlig455_058015 {REF} {Length: 1913} {Pfam: ML domain [PF02221.17, score=41.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=52.0, Expect=4e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=53.9, Expect=6e-09]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=73.9, Expect=6e-17]} {RNA1509_4247} {RNA1310_43150} {RNA815_23642.1}

Mlig455_058180 {REF} {Length: 1416} {Pfam: ML domain [PF02221.17, score=41.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=52.0, Expect=4e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=53.9, Expect=6e-09]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=73.9, Expect=6e-17]} {RNA1509_4247} {RNA1310_43150} {RNA815_23642.1}

Mlig455_058206 {REF} {Length: 1589} {Pfam: ML domain [PF02221.17, score=41.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=52.0, Expect=4e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=53.9, Expect=6e-09]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=73.9, Expect=6e-17]} {RNA1509_3837, RNA1509_4247, RNA1509_4841, RNA1509_5347} {RNA1310_43150, RNA1509_3837, RNA1509_4247, RNA1509_4841, RNA1509_5347} {RNA1509_3837, RNA1509_4247, RNA1509_4841, RNA1509_5347, RNA815_23642.1}
10. MligTC455_42921 2549 53.1 Mlig455_026303, Mlig455_026319

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.315

Region-enriched R3: 3.759/0.00000
Region-enriched R4: 1.949/0.01034

4.557 0.957 0.854 - 0.919 0.848 0.979

Mlig455_026303 {REF} {Length: 811} {Pfam: Group 7 allergen [PF16984.7, score=52.6]} {RNA1509_4404} {RNA1310_17894} {RNA815_9024}

Mlig455_026319 {REF} {Length: 1051} {Pfam: Group 7 allergen [PF16984.7, score=52.6]} {RNA1509_4404} {RNA1310_17894} {RNA815_9024}
11. MligTC455_36391 24307 506.39 Mlig455_045125, Mlig455_045159

Neo: -

Age: logFC(26M/2M)=-0.927

Region-enriched R3: 3.255/0.00000
Region-enriched R4: 1.880/0.01518
Region-enriched R5: 1.642/0.01149

PROC 4.555 0.975 0.901 - 0.933 0.907 0.839

Mlig455_045125 {REF} {Length: 929} {Pfam: Trypsin [PF00089.28, score=94.8]; Trypsin-like peptidase domain [PF13365.8, score=36.8]} {Human: ENSG00000115718, PROC, protein C, inactivator of coagulation factors Va and VIIIa, [Score=62.4, Expect=8e-11]; ENSG00000172236, TPSAB1, tryptase alpha/beta 1, [Score=59.3, Expect=4e-10]} {Mouse: ENSMUSG00000024386, Proc, protein C, [Score=70.9, Expect=8e-14]; ENSMUSG00000050063, Klk6, kallikrein related-peptidase 6, [Score=68.6, Expect=1e-13]} {Dmel: FBgn0036738, CG7542, [Score=80.1, Expect=1e-17]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [RH, Score=115, Expect=7e-32]} {RNA1509_15040, RNA1509_19320, RNA1509_2113, RNA1509_39015, RNA1509_39167, RNA1509_4268, RNA1509_49096, RNA1509_9437} {RNA1310_47138.1, RNA1509_15040, RNA1509_19320, RNA1509_2113, RNA1509_39015, RNA1509_39167, RNA1509_4268, RNA1509_49096, RNA1509_9437} {RNA1509_15040, RNA1509_19320, RNA1509_2113, RNA1509_39015, RNA1509_39167, RNA1509_4268, RNA1509_49096, RNA1509_9437, RNA815_8541.2}

Mlig455_045159 {REF} {Length: 929} {Pfam: Trypsin [PF00089.28, score=94.8]; Trypsin-like peptidase domain [PF13365.8, score=36.8]} {Human: ENSG00000115718, PROC, protein C, inactivator of coagulation factors Va and VIIIa, [Score=62.4, Expect=8e-11]; ENSG00000172236, TPSAB1, tryptase alpha/beta 1, [Score=59.3, Expect=4e-10]} {Mouse: ENSMUSG00000024386, Proc, protein C, [Score=70.9, Expect=8e-14]; ENSMUSG00000050063, Klk6, kallikrein related-peptidase 6, [Score=68.6, Expect=1e-13]} {Dmel: FBgn0036738, CG7542, [Score=80.1, Expect=1e-17]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [RH, Score=115, Expect=7e-32]} {RNA1509_19320} {RNA1310_47138.1} {RNA815_8541.2}
12. MligTC455_28572 795 16.56 Mlig455_003711, Mlig455_003877

Neo: -

Age: logFC(26M/2M)=0.820

Region-enriched R3: 3.765/0.00000

4.549 0.957 0.910 - 0.982 0.862 0.838

Mlig455_003711 {REF} {Length: 988} {RNA1509_11217} {RNA1310_24401} {RNA815_10016}

Mlig455_003877 {REF} {Length: 2523} {RNA1509_11217} {RNA1310_24401} {RNA815_10016}
13. MligTC455_37229 2478 51.62 Mlig455_032508

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.174

Region-enriched R3: 3.182/0.00000
Region-enriched R4: 2.943/0.00000
Region-enriched R5: 1.378/0.01245

4.546 0.969 0.741 - 0.967 0.960 0.909 Mlig455_032508 {REF} {Length: 1706} {RNA1509_3944, RNA1509_7667} {RNA1310_29763.1, RNA1509_3944, RNA1509_7667} {RNA1509_3944, RNA1509_7667, RNA815_14819.1}
14. MligTC455_15448 1109 23.1 Mlig455_051485

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=2.807

Region-enriched R3: 5.610/0.00000
Region-enriched R4: 4.154/0.00029

MEP1B 4.537 0.899 0.869 0.890 0.960 - 0.919 Mlig455_051485 {REF} {Length: 966} {Pfam: Astacin (Peptidase family M12A) [PF01400.26, score=152.5]} {Human: ENSG00000141434, MEP1B, meprin A subunit beta, [Score=105, Expect=3e-25]; ENSG00000188886, ASTL, astacin like metalloendopeptidase, [Score=100, Expect=7e-24]} {Mouse: ENSMUSG00000024313, Mep1b, meprin 1 beta, [Score=104, Expect=4e-25]; ENSMUSG00000023914, Mep1a, meprin 1 alpha, [Score=102, Expect=2e-24]; ENSMUSG00000053626, Tll1, tolloid-like, [Score=99.4, Expect=2e-23]} {Dmel: FBgn0028949, CG15254, [Score=119, Expect=3e-32]} {Celegans: WBGene00003523, nas-4, Zinc metalloproteinase nas-4, [Score=119, Expect=4e-32]} {Smed: dd_Smed_v6_51_1_2, dd_Smed_v6_51_1_2, [RH, Score=148, Expect=7e-44]} {RNA1509_16597, RNA1509_2724} {RNA1310_37686, RNA1509_16597, RNA1509_2724} {RNA1509_16597, RNA1509_2724, RNA815_17836}
15. MligTC455_51131 5808 120.99 Mlig455_031629

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.484

Region-enriched R3: 3.757/0.00000
Region-enriched R4: 2.189/0.01454

4.515 0.954 0.947 - 0.733 0.927 0.954 Mlig455_031629 {REF} {Length: 1657} {Pfam: Glycosyl hydrolases family 16 [PF00722.23, score=60.4]} {Dmel: FBgn0040323, GNBP1, Gram-negative bacteria binding protein 1, [RH, Score=160, Expect=4e-44]} {RNA1509_304} {RNA1310_18175.2} {RNA815_10892.1}
16. MligTC455_27242 14489 301.86 Mlig455_056957

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.849

Region-enriched R3: 2.848/0.00000
Region-enriched R5: 1.349/0.04924

GM2A 4.505 0.891 0.909 - 0.801 0.932 0.972 Mlig455_056957 {REF} {Length: 877} {Pfam: ML domain [PF02221.17, score=41.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=51.6, Expect=7e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=50.8, Expect=1e-07]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=56.2, Expect=3e-10]} {RNA1509_960} {RNA1310_28835.1} {RNA815_6681.1}
17. MligTC455_18469 533 11.11 Mlig455_070391

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.656

4.498 0.926 - 0.825 0.890 0.896 0.961 Mlig455_070391 {REF} {Length: 1452} {Pfam: Lipase (class 3) [PF01764.27, score=96.6]} {Celegans: WBGene00022457, Y110A7A.7, [Score=157, Expect=1e-44]} {RNA1509_36256, RNA1509_36380} {RNA1310_22408, RNA1509_36380} {RNA1509_36380, RNA815_9975}
18. MligTC455_44574 3417 71.2 Mlig455_029253

Neo: -

Age: logFC(26M/2M)=1.203

Region-enriched R3: 3.526/0.00000
Region-enriched R4: 2.436/0.00118

NPC2 4.478 0.917 0.973 - 0.916 0.897 0.775 Mlig455_029253 {REF} {Length: 746} {Pfam: ML domain [PF02221.17, score=97.3]} {Human: ENSG00000119655, NPC2, NPC intracellular cholesterol transporter 2, [RH, Score=136, Expect=2e-40]} {Mouse: ENSMUSG00000021242, Npc2, NPC intracellular cholesterol transporter 2, [RH, Score=132, Expect=5e-40]} {Dmel: FBgn0031381, Npc2a, Niemann-Pick type C-2a, [RH, Score=144, Expect=1e-44]} {Smed: dd_Smed_v6_602_0_1, dd_Smed_v6_602_0_1, [RH, Score=139, Expect=6e-43]} {RNA1509_5159} {RNA1310_51205, RNA1509_5159} {RNA1509_5159, RNA815_27598}
19. MligTC455_39422 15237 317.44 Mlig455_038446, Mlig455_038587

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.458

Region-enriched R3: 3.133/0.00000
Region-enriched R4: 1.698/0.02538
Region-enriched R5: 1.391/0.02987

MRC1 4.443 0.938 0.862 - 0.954 0.752 0.937

Mlig455_038446 {REF} {Length: 1218} {Pfam: Lectin C-type domain [PF00059.23, score=95.6]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=37.9]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [Score=77.8, Expect=5e-15]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=58.5, Expect=7e-09]; ENSMUSG00000020695, Mrc2, mannose receptor, C type 2, [Score=58.2, Expect=7e-09]; ENSMUSG00000020884, Asgr1, asialoglycoprotein receptor 1, [Score=57.4, Expect=4e-09]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [Score=58.2, Expect=2e-09]} {Smed: dd_Smed_v6_1489_0_1, dd_Smed_v6_1489_0_1, [Score=51.6, Expect=2e-07]} {RNA1509_980} {RNA1310_5522.1} {RNA815_4429}

Mlig455_038587 {REF} {Length: 1225} {Pfam: Lectin C-type domain [PF00059.23, score=93.7]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=39.2]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [Score=74.3, Expect=7e-14]} {Mouse: ENSMUSG00000020695, Mrc2, mannose receptor, C type 2, [Score=60.1, Expect=2e-09]; ENSMUSG00000020884, Asgr1, asialoglycoprotein receptor 1, [Score=58.2, Expect=3e-09]; ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=57.4, Expect=1e-08]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [Score=54.3, Expect=4e-08]} {Smed: dd_Smed_v6_1489_0_1, dd_Smed_v6_1489_0_1, [Score=51.2, Expect=4e-07]} {RNA1509_13839, RNA1509_25500, RNA1509_980} {RNA1310_5522.1, RNA1509_13839, RNA1509_25500} {RNA1509_13839, RNA1509_25500, RNA815_4429}
20. MligTC455_38477 31831 663.15 Mlig455_025486, Mlig455_025508

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.748

Region-enriched R3: 3.522/0.00000
Region-enriched R4: 2.336/0.00577

TMPRSS15 4.441 0.957 0.939 - 0.791 0.920 0.834

Mlig455_025486 {REF} {Length: 1201} {Pfam: Trypsin [PF00089.28, score=254.3]; Trypsin-like peptidase domain [PF13365.8, score=38.5]; Domain of unknown function (DUF1986) [PF09342.13, score=34.2]} {Human: ENSG00000154646, TMPRSS15, transmembrane serine protease 15, [RH, Score=198, Expect=3e-57]; ENSG00000274058, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=194, Expect=4e-59]; ENSG00000087128, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=193, Expect=1e-58]; ENSG00000105707, HPN, hepsin, [RH, Score=191, Expect=9e-58]} {Mouse: ENSMUSG00000001249, Hpn, hepsin, [RH, Score=195, Expect=1e-59]; ENSMUSG00000030800, Prss8, protease, serine 8 (prostasin), [RH, Score=191, Expect=8e-59]} {Dmel: FBgn0051954, CG31954, [RH, Score=159, Expect=2e-47]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=164, Expect=4e-49]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=172, Expect=1e-48]} {RNA1509_237, RNA1509_4457} {RNA1310_26444, RNA1509_237, RNA1509_4457} {RNA1509_237, RNA1509_4457, RNA815_9945}

Mlig455_025508 {REF} {Length: 1613} {Pfam: Trypsin [PF00089.28, score=254.3]; Trypsin-like peptidase domain [PF13365.8, score=38.5]; Domain of unknown function (DUF1986) [PF09342.13, score=34.2]} {Human: ENSG00000154646, TMPRSS15, transmembrane serine protease 15, [RH, Score=198, Expect=3e-57]; ENSG00000274058, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=194, Expect=4e-59]; ENSG00000087128, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=193, Expect=1e-58]; ENSG00000105707, HPN, hepsin, [RH, Score=191, Expect=9e-58]} {Mouse: ENSMUSG00000001249, Hpn, hepsin, [RH, Score=195, Expect=1e-59]; ENSMUSG00000030800, Prss8, protease, serine 8 (prostasin), [RH, Score=191, Expect=8e-59]} {Dmel: FBgn0051954, CG31954, [RH, Score=159, Expect=2e-47]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=164, Expect=4e-49]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=172, Expect=1e-48]} {RNA1509_237} {RNA1310_26444} {RNA815_9945}
21. MligTC455_31631 977 20.36 Mlig455_038575

Neo: -

Age: -

Region-enriched R3: 3.163/0.00000
Region-enriched R4: 1.482/0.02038

4.437 0.927 0.819 - 0.913 0.827 0.951 Mlig455_038575 {REF} {Length: 1498} {Smed: dd_Smed_v6_279_0_1, dd_Smed_v6_279_0_1, [RH, Score=178, Expect=6e-51]} {RNA1509_14693, RNA1509_21145} {RNA1310_23343, RNA1509_14693} {RNA1509_14693, RNA815_10091}
22. MligTC455_28661 1197 24.95 Mlig455_003667

Neo: -

Age: logFC(26M/2M)=0.386

Region-enriched R3: 3.225/0.00000
Region-enriched R4: 1.619/0.02931

4.433 0.950 0.877 - 0.756 0.875 0.975 Mlig455_003667 {REF} {Length: 2846} {RNA1509_11217, RNA1509_19513, RNA1509_20197} {RNA1310_24401, RNA1509_11217, RNA1509_19513, RNA1509_20197} {RNA1509_11217, RNA1509_19513, RNA1509_20197, RNA815_10016}
23. MligTC455_37186 4329 90.18 Mlig455_049358

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=1.615

Region-enriched R3: 2.564/0.00000
Region-enriched R5: 1.518/0.00929

4.41 0.939 0.721 - 0.932 0.976 0.842 Mlig455_049358 {REF} {Length: 1834} {Pfam: QacR-like protein, C-terminal region [PF08360.13, score=18.9]} {RNA1509_252} {RNA1310_4046.2} {RNA815_6338.1}
24. MligTC455_46997 1302 27.12 Mlig455_018324

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.900

Region-enriched R4: 3.072/0.00026
Region-enriched R3: 2.531/0.00058
Region-enriched R5: 1.786/0.01855

CPA2 4.403 0.767 0.821 - 0.971 0.922 0.922 Mlig455_018324 {REF} {Length: 1747} {Pfam: Zinc carboxypeptidase [PF00246.26, score=269.1]; Carboxypeptidase activation peptide [PF02244.18, score=54.2]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2, [RH, Score=287, Expect=3e-93]} {Mouse: ENSMUSG00000071553, Cpa2, carboxypeptidase A2, pancreatic, [RH, Score=288, Expect=2e-93]} {Dmel: FBgn0029807, CG3108, [RH, Score=266, Expect=8e-80]} {Celegans: WBGene00008521, F02D8.4, [RH, Score=251, Expect=3e-79]} {Smed: dd_Smed_v6_5999_0_1, dd_Smed_v6_5999_0_1, [RH, Score=254, Expect=1e-80]} {RNA1509_11873, RNA1509_20365} {RNA1310_21434, RNA1509_11873, RNA1509_20365} {RNA1509_11873, RNA1509_20365, RNA815_8679}
25. MligTC455_37187 7422 154.63 Mlig455_062308

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.525

Region-enriched R3: 2.316/0.00013
Region-enriched R4: 1.803/0.01751
Region-enriched R5: 1.643/0.00908

4.395 0.937 0.720 - 0.889 0.950 0.899 Mlig455_062308 {REF} {Length: 1837} {Pfam: QacR-like protein, C-terminal region [PF08360.13, score=18.9]} {RNA1509_252, RNA1509_46852} {RNA1310_4046.2, RNA1509_252, RNA1509_46852} {RNA1509_252, RNA1509_46852, RNA815_6338.1}
26. MligTC455_17786 5712 118.99 Mlig455_018639

Neo: -

Age: logFC(26M/2M)=0.505

Region-enriched R3: 2.605/0.00046

4.383 0.948 0.856 - 0.709 0.895 0.975 Mlig455_018639 {REF} {Length: 577} {RNA1509_4836} {RNA1310_1935.1} {RNA815_12746}
27. MligTC455_53287 6775 141.16 Mlig455_026427, Mlig455_026458, Mlig455_044750

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=2.125

Region-enriched R3: 3.677/0.00000

4.347 0.863 0.917 - 0.782 0.822 0.963

Mlig455_026427 {REF} {Length: 1166} {RNA1509_15587} {RNA1310_35864} {RNA815_17135}

Mlig455_026458 {REF} {Length: 978} {RNA1509_1133, RNA1509_15587} {RNA1310_35864, RNA1509_1133, RNA1509_15587} {RNA1509_1133, RNA1509_15587, RNA815_17135}

Mlig455_044750 {REF} {Length: 1007} {RNA1509_1133} {RNA1310_35864} {RNA815_17135}
28. MligTC455_12850 218 4.54 Mlig455_023234, Mlig455_023300

Neo: -

Age: logFC(26M/2M)=0.710

Region-enriched R3: 4.577/0.00001
Region-enriched R4: 4.285/0.00027

4.321 0.771 0.843 - 0.975 0.755 0.977

Mlig455_023234 {REF} {Length: 1028} {Pfam: Lipase (class 2) [PF01674.20, score=119.2]} {Celegans: WBGene00011725, lips-5, LIPaSe related, [Score=130, Expect=4e-37]} {RNA1509_38856} {RNA1310_33908} {RNA815_16748}

Mlig455_023300 {REF} {Length: 1050} {Pfam: Lipase (class 2) [PF01674.20, score=191.0]} {Celegans: WBGene00011725, lips-5, LIPaSe related, [RH, Score=179, Expect=6e-54]} {RNA1509_38856} {RNA1310_33908, RNA1509_38856} {RNA1509_38856, RNA815_16748}
29. MligTC455_38482 16675 347.39 Mlig455_035458, Mlig455_070530

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.639

Region-enriched R3: 3.465/0.00000
Region-enriched R4: 2.322/0.00388

TMPRSS15 4.321 0.959 0.937 - 0.809 0.915 0.701

Mlig455_035458 {REF} {Length: 302} {Pfam: Motilin/ghrelin-associated peptide [PF04643.14, score=20.2]}

Mlig455_070530 {REF} {Length: 1350} {Pfam: Trypsin [PF00089.28, score=253.0]; Trypsin-like peptidase domain [PF13365.8, score=38.5]; Domain of unknown function (DUF1986) [PF09342.13, score=34.6]} {Human: ENSG00000154646, TMPRSS15, transmembrane serine protease 15, [RH, Score=195, Expect=3e-56]; ENSG00000087128, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=194, Expect=7e-59]; ENSG00000274058, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=194, Expect=7e-59]; ENSG00000105707, HPN, hepsin, [RH, Score=189, Expect=5e-57]} {Mouse: ENSMUSG00000001249, Hpn, hepsin, [RH, Score=197, Expect=3e-60]; ENSMUSG00000030800, Prss8, protease, serine 8 (prostasin), [RH, Score=192, Expect=2e-59]} {Dmel: FBgn0051954, CG31954, [RH, Score=160, Expect=1e-47]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=164, Expect=3e-49]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=173, Expect=5e-49]} {RNA1509_237, RNA1509_33683} {RNA1310_26444, RNA1509_33683} {RNA1509_33683, RNA815_9945}
30. MligTC455_43896 2951 61.47 Mlig455_040892

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.666

Region-enriched R3: 2.882/0.00000
Region-enriched R4: 1.676/0.03092

PLA2G15 4.194 0.837 0.790 - 0.971 0.769 0.827 Mlig455_040892 {REF} {Length: 1791} {Pfam: Lecithin:cholesterol acyltransferase [PF02450.17, score=205.7]; Alpha/beta hydrolase family [PF12697.9, score=27.5]; Serine hydrolase [PF06821.15, score=21.3]; Serine aminopeptidase, S33 [PF12146.10, score=18.9]} {Human: ENSG00000103066, PLA2G15, phospholipase A2 group XV, [Score=256, Expect=2e-81]} {Mouse: ENSMUSG00000031903, Pla2g15, phospholipase A2, group XV, [Score=236, Expect=1e-73]; ENSMUSG00000035237, Lcat, lecithin cholesterol acyltransferase, [Score=230, Expect=6e-71]} {Dmel: FBgn0042175, CG18858, [Score=229, Expect=4e-71]} {Celegans: WBGene00010872, M05B5.4, [RH, Score=277, Expect=1e-89]} {Smed: dd_Smed_v6_8328_0_1, dd_Smed_v6_8328_0_1, [RH, Score=257, Expect=2e-82]} {RNA1509_858, RNA1509_9645} {RNA1310_22091, RNA1509_9645} {RNA1509_9645, RNA815_9147}
31. MligTC455_44575 2452 51.08 Mlig455_035640

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.660

Region-enriched R3: 3.475/0.00000
Region-enriched R4: 2.557/0.00024
Region-enriched R5: 1.438/0.02794

NPC2 3.689 0.920 0.967 - 0.872 0.930 - Mlig455_035640 {REF} {Length: 724} {Pfam: ML domain [PF02221.17, score=97.3]} {Human: ENSG00000119655, NPC2, NPC intracellular cholesterol transporter 2, [RH, Score=136, Expect=2e-40]} {Mouse: ENSMUSG00000021242, Npc2, NPC intracellular cholesterol transporter 2, [RH, Score=132, Expect=5e-40]} {Dmel: FBgn0031381, Npc2a, Niemann-Pick type C-2a, [RH, Score=144, Expect=1e-44]} {Smed: dd_Smed_v6_602_0_1, dd_Smed_v6_602_0_1, [RH, Score=139, Expect=6e-43]} {RNA1509_4097} {RNA1310_51205} {RNA815_27598}
32. MligTC455_46996 4098 85.37 Mlig455_008353

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=2.299

Region-enriched R3: 2.953/0.00000
Region-enriched R4: 2.228/0.00001
Region-enriched R5: 1.438/0.00273

CPA2 3.668 0.857 - - 0.889 0.968 0.954 Mlig455_008353 {REF} {Length: 1388} {Pfam: Zinc carboxypeptidase [PF00246.26, score=268.1]; Carboxypeptidase activation peptide [PF02244.18, score=51.5]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2, [RH, Score=281, Expect=6e-91]} {Mouse: ENSMUSG00000071553, Cpa2, carboxypeptidase A2, pancreatic, [RH, Score=278, Expect=5e-90]; ENSMUSG00000029788, Cpa5, carboxypeptidase A5, [RH, Score=269, Expect=5e-86]} {Dmel: FBgn0029807, CG3108, [RH, Score=268, Expect=1e-80]} {Celegans: WBGene00008521, F02D8.4, [RH, Score=251, Expect=2e-79]} {Smed: dd_Smed_v6_5999_0_1, dd_Smed_v6_5999_0_1, [RH, Score=251, Expect=1e-79]} {RNA1509_861} {RNA1310_21434, RNA1509_861} {RNA1509_861, RNA815_8679}
33. MligTC455_43194 11396 237.42 Mlig455_009763, Mlig455_070122

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.399/0.00716

CST3 3.658 0.947 - - 0.804 0.930 0.977

Mlig455_009763 {REF} {Length: 720} {Pfam: Cystatin domain [PF00031.23, score=28.8]} {Human: ENSG00000101439, CST3, cystatin C, [RH, Score=44.7, Expect=6e-06]} {RNA1509_26463, RNA1509_2883, RNA1509_6502} {RNA1310_51190, RNA1509_2883, RNA1509_6502} {RNA1509_2883, RNA1509_6502, RNA815_25269}

Mlig455_070122 {REF} {Length: 736} {Pfam: Cystatin domain [PF00031.23, score=28.8]} {Human: ENSG00000101439, CST3, cystatin C, [RH, Score=44.7, Expect=6e-06]} {RNA1509_26463, RNA1509_4516, RNA1509_5046, RNA1509_7022} {RNA1310_51190, RNA1509_26463, RNA1509_4516, RNA1509_5046, RNA1509_7022} {RNA1509_26463, RNA1509_4516, RNA1509_5046, RNA1509_7022, RNA815_25269}
34. MligTC455_44576 827 17.23 Mlig455_035737

Neo: -

Age: Down-Down-Down

Region-enriched R3: 3.810/0.00000
Region-enriched R4: 2.716/0.00215

NPC2 3.633 0.913 0.969 - 0.774 - 0.977 Mlig455_035737 {REF} {Length: 750} {Pfam: ML domain [PF02221.17, score=97.3]} {Human: ENSG00000119655, NPC2, NPC intracellular cholesterol transporter 2, [RH, Score=136, Expect=2e-40]} {Mouse: ENSMUSG00000021242, Npc2, NPC intracellular cholesterol transporter 2, [RH, Score=132, Expect=5e-40]} {Dmel: FBgn0031381, Npc2a, Niemann-Pick type C-2a, [RH, Score=144, Expect=1e-44]} {Smed: dd_Smed_v6_602_0_1, dd_Smed_v6_602_0_1, [RH, Score=139, Expect=6e-43]} {RNA1509_4097, RNA1509_41414} {RNA1310_51205, RNA1509_4097, RNA1509_41414} {RNA1509_4097, RNA1509_41414, RNA815_27598}
35. MligTC455_20085 208 4.33 Mlig455_034798

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.706

Region-enriched R4: 3.501/0.01114
Region-enriched R3: 3.474/0.00597

DNASE1L3 3.624 0.827 0.844 - 0.982 - 0.971 Mlig455_034798 {REF} {Length: 1749} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=38.1]} {Human: ENSG00000163687, DNASE1L3, deoxyribonuclease 1 like 3, [RH, Score=184, Expect=2e-54]; ENSG00000167968, DNASE1L2, deoxyribonuclease 1 like 2, [RH, Score=183, Expect=4e-54]; ENSG00000213918, DNASE1, deoxyribonuclease 1, [RH, Score=181, Expect=1e-53]} {Mouse: ENSMUSG00000025279, Dnase1l3, deoxyribonuclease 1-like 3, [RH, Score=184, Expect=4e-54]; ENSMUSG00000024136, Dnase1l2, deoxyribonuclease 1-like 2, [RH, Score=178, Expect=2e-52]; ENSMUSG00000005980, Dnase1, deoxyribonuclease I, [RH, Score=178, Expect=3e-52]} {RNA1509_8194} {RNA1310_18116} {RNA815_13867}
36. MligTC455_52855 748 15.59 Mlig455_029551, Mlig455_040460

Neo: -

Age: -

Region-enriched R3: 5.112/0.00000
Region-enriched R4: 3.658/0.00041
Region-enriched R5: 3.118/0.00161

MCFD2 3.599 0.925 0.856 - 0.852 - 0.966

Mlig455_029551 {REF} {Length: 937} {Pfam: EF-hand domain pair [PF13499.8, score=45.6]; EF-hand domain [PF13405.8, score=36.2]; EF hand [PF00036.34, score=36.1]; EF-hand domain pair [PF13833.8, score=25.7]} {Human: ENSG00000180398, MCFD2, multiple coagulation factor deficiency 2, [Score=62.0, Expect=5e-12]} {Mouse: ENSMUSG00000024150, Mcfd2, multiple coagulation factor deficiency 2, [Score=60.1, Expect=2e-11]} {Dmel: FBgn0037798, CG12817, [RH, Score=53.5, Expect=6e-09]} {Celegans: WBGene00010075, F55A11.1, [RH, Score=70.1, Expect=3e-15]} {RNA1509_28625} {RNA1310_37099} {RNA815_18915}

Mlig455_040460 {REF} {Length: 1066} {Pfam: EF-hand domain pair [PF13499.8, score=41.5]; EF hand [PF00036.34, score=36.3]; EF-hand domain [PF13405.8, score=36.3]; EF-hand domain pair [PF13833.8, score=25.9]} {Human: ENSG00000180398, MCFD2, multiple coagulation factor deficiency 2, [Score=61.6, Expect=6e-12]} {Mouse: ENSMUSG00000024150, Mcfd2, multiple coagulation factor deficiency 2, [Score=60.1, Expect=1e-11]} {Dmel: FBgn0037798, CG12817, [RH, Score=53.5, Expect=4e-09]} {Celegans: WBGene00010075, F55A11.1, [RH, Score=70.1, Expect=2e-15]} {RNA1509_11624, RNA1509_17013, RNA1509_28625} {RNA1310_37099, RNA1509_11624, RNA1509_17013, RNA1509_28625} {RNA1509_11624, RNA1509_17013, RNA1509_28625, RNA815_18915}
37. MligTC455_33964 17054 355.3 Mlig455_057690

Neo: -

Age: -

Region-enriched R3: 3.681/0.00000
Region-enriched R4: 2.185/0.00615

3.593 0.963 0.879 - - 0.970 0.781 Mlig455_057690 {REF} {Length: 582} {Pfam: Destabilase [PF05497.14, score=88.9]} {Dmel: FBgn0025827, CG6421, [Score=46.2, Expect=1e-06]} {Celegans: WBGene00016670, ilys-3, Invertebrate-type lysozyme 3, [Score=80.5, Expect=7e-20]} {RNA1509_25524} {RNA1310_5040} {RNA815_13101.1}
38. MligTC455_33965 17062 355.46 Mlig455_057693

Neo: -

Age: logFC(26M/2M)=-0.368

Region-enriched R3: 3.675/0.00000
Region-enriched R4: 2.192/0.00569

3.593 0.963 0.879 - - 0.970 0.781 Mlig455_057693 {REF} {Length: 618} {Pfam: Destabilase [PF05497.14, score=88.9]} {Dmel: FBgn0025827, CG6421, [Score=46.2, Expect=1e-06]} {Celegans: WBGene00016670, ilys-3, Invertebrate-type lysozyme 3, [Score=80.5, Expect=7e-20]} {RNA1509_25524} {RNA1310_5040} {RNA815_13101.2}
39. MligTC455_40545 1143 23.82 Mlig455_055297

Neo: -

Age: Down-Down-Up

Region-enriched R3: 3.033/0.00012

3.538 - 0.843 - 0.963 0.756 0.976 Mlig455_055297 {REF} {Length: 1850} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=40.2]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=38.9]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=22.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=21.3]; FAD binding domain [PF01494.21, score=19.7]} {RNA1509_13298, RNA1509_15869} {RNA1310_17901, RNA1509_15869} {RNA1509_15869, RNA815_2201}
40. MligTC455_18468 49 1.02 Mlig455_014453

Neo: -

Age: -

Region-enriched R4: 3.552/0.03158

3.528 0.966 - - 0.863 0.897 0.802 Mlig455_014453 {REF} {Length: 1446} {Pfam: Lipase (class 3) [PF01764.27, score=96.6]} {Celegans: WBGene00022457, Y110A7A.7, [Score=158, Expect=6e-45]} {RNA1509_36256} {RNA1310_22408} {RNA815_9975}
41. MligTC455_21680 724 15.08 Mlig455_000605, Mlig455_034134

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.732

Region-enriched R3: 2.466/0.00387
Region-enriched R4: 2.148/0.02841
Region-enriched R5: 1.792/0.02276

ENDOU 3.356 0.827 0.758 - 0.967 0.804 -

Mlig455_000605 {REF} {Length: 1158} {Pfam: Endoribonuclease XendoU [PF09412.12, score=131.5]} {Human: ENSG00000111405, ENDOU, endonuclease, poly(U) specific, [Score=104, Expect=1e-25]} {Mouse: ENSMUSG00000022468, Endou, endonuclease, polyU-specific, [Score=112, Expect=2e-28]} {Dmel: FBgn0030251, CG2145, [Score=91.7, Expect=1e-20]} {Celegans: WBGene00010488, endu-1, Poly(U)-specific endoribonuclease homolog, [Score=95.5, Expect=5e-23]} {Smed: dd_Smed_v6_9109_0_1, dd_Smed_v6_9109_0_1, [Score=88.6, Expect=9e-21]} {RNA1509_53582} {RNA1310_25491.1} {RNA815_11062.1}

Mlig455_034134 {REF} {Length: 1307} {Pfam: Endoribonuclease XendoU [PF09412.12, score=171.0]} {Human: ENSG00000111405, ENDOU, endonuclease, poly(U) specific, [Score=124, Expect=3e-32]} {Mouse: ENSMUSG00000022468, Endou, endonuclease, polyU-specific, [Score=125, Expect=2e-32]} {Dmel: FBgn0030251, CG2145, [Score=102, Expect=6e-24]} {Celegans: WBGene00010488, endu-1, Poly(U)-specific endoribonuclease homolog, [Score=104, Expect=1e-25]} {Smed: dd_Smed_v6_9109_0_1, dd_Smed_v6_9109_0_1, [Score=99.0, Expect=5e-24]} {RNA1509_35253, RNA1509_53582} {RNA1310_25491.1, RNA1509_35253} {RNA1509_35253, RNA815_11062.1}
42. MligTC455_47626 80 1.66 Mlig455_006025

Neo: -

Age: logFC(26M/2M)=1.286

Region-enriched R4: 3.271/0.02922

3.259 - 0.726 - 0.963 0.734 0.836 Mlig455_006025 {REF} {Length: 2278} {Smed: dd_Smed_v6_71482_0_1, dd_Smed_v6_71482_0_1, [Score=55.8, Expect=1e-10]} {RNA1509_11049} {RNA1310_42264.2} {RNA815_29319}
43. MligTC455_18466 2786 58.04 Mlig455_005607

Neo: -

Age: logFC(26M/2M)=0.391

Region-enriched R3: 1.999/0.00016
Region-enriched R4: 1.673/0.00718
Region-enriched R5: 1.508/0.00283

2.802 0.911 - - - 0.953 0.938 Mlig455_005607 {REF} {Length: 1941} {Pfam: Lipase (class 3) [PF01764.27, score=94.6]} {Celegans: WBGene00022457, Y110A7A.7, [Score=154, Expect=9e-44]} {RNA1509_36256, RNA1509_4777, RNA1509_8532} {RNA1310_22408, RNA1509_36256, RNA1509_4777, RNA1509_8532} {RNA1509_36256, RNA1509_4777, RNA1509_8532, RNA815_9975}
44. MligTC455_26184 7464 155.49 Mlig455_021322

Neo: Germline

Age: -

Region-enriched R3: 2.553/0.00001
Region-enriched R4: 1.898/0.00795

2.761 0.832 - - - 0.959 0.970 Mlig455_021322 {REF} {Length: 496} {TRANSSPLICED} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=31.0]} {RNA1509_2946, RNA1509_56087, RNA1509_7601} {RNA1310_20339, RNA1509_2946, RNA1509_56087, RNA1509_7601} {RNA1509_2946, RNA1509_56087, RNA1509_7601, RNA815_31444.2}
45. MligTC455_25067 1268 26.41 Mlig455_010546, Mlig455_061790, Mlig455_061830

Neo: -

Age: Down-Down-Up

Region-enriched R3: 3.775/0.00039
Region-enriched R4: 2.755/0.02795
Region-enriched R5: 2.464/0.02341

2.76 0.983 - - - 0.829 0.948

Mlig455_010546 {REF} {Length: 1067} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=23.7]} {RNA1509_10254, RNA1509_23808} {RNA1310_73349, RNA1509_10254, RNA1509_23808} {RNA1509_10254, RNA1509_23808, RNA815_41780}

Mlig455_061790 {REF} {Length: 642} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=23.7]} {RNA1509_23808} {RNA1310_73349} {RNA815_41780}

Mlig455_061830 {REF} {Length: 681} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=23.7]} {RNA1509_23808} {RNA1310_73349} {RNA815_41780}
46. MligTC455_22200 764 15.92 Mlig455_018539

Neo: Germline

Age: Up-Down-Up, logFC(26M/2M)=0.330

Region-enriched R4: 2.959/0.00000
Region-enriched R3: 2.286/0.00001

2.747 - - - 0.886 0.951 0.910 Mlig455_018539 {REF} {Length: 876} {Pfam: HD domain [PF01966.24, score=24.2]} {RNA1509_10650} {RNA1310_34853.2, RNA1509_10650} {RNA1509_10650, RNA815_15543}
47. MligTC455_48965 1168 24.33 Mlig455_019177

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.985

Region-enriched R3: 2.779/0.00000
Region-enriched R4: 1.466/0.04740

AGRN 2.744 0.980 - - 0.842 - 0.922 Mlig455_019177 {REF} {Length: 1281} {Pfam: Kazal-type serine protease inhibitor domain [PF00050.23, score=71.9]; Kazal-type serine protease inhibitor domain [PF07648.17, score=68.0]; Cyclin [PF08613.13, score=19.4]} {Human: ENSG00000188157, AGRN, agrin, [Score=46.2, Expect=5e-06]} {Mouse: ENSMUSG00000028476, Reck, reversion-inducing-cysteine-rich protein with kazal motifs, [Score=44.7, Expect=1e-05]} {Dmel: FBgn0052354, CG32354, [Score=48.5, Expect=4e-07]} {Celegans: WBGene00018304, agr-1, AGRin (Synaptic protein) homolog; AGRin (Synaptic protein) homolog family member, [Score=48.9, Expect=2e-07]} {RNA1509_14482, RNA1509_22745} {RNA1310_50630, RNA1509_14482, RNA1509_22745} {RNA1509_14482, RNA1509_22745, RNA815_28906}
48. MligTC455_37984 116 2.41 Mlig455_067499

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.021

2.663 - 0.836 - 0.975 - 0.852 Mlig455_067499 {REF} {Length: 1399} {Pfam: N-formylglutamate amidohydrolase [PF05013.14, score=41.7]} {RNA1509_54585} {RNA1310_30092.1} {RNA815_15032}
49. MligTC455_12956 260 5.41 Mlig455_013752

Neo: -

Age: logFC(26M/2M)=3.929

Region-enriched R3: 5.406/0.00000
Region-enriched R4: 3.999/0.00332

TLL1 2.647 0.819 - - 0.951 - 0.877 Mlig455_013752 {REF} {Length: 1191} {Pfam: Astacin (Peptidase family M12A) [PF01400.26, score=173.5]} {Human: ENSG00000038295, TLL1, tolloid like 1, [Score=127, Expect=5e-34]; ENSG00000095587, TLL2, tolloid like 2, [Score=121, Expect=8e-31]} {Mouse: ENSMUSG00000053626, Tll1, tolloid-like, [Score=126, Expect=9e-33]; ENSMUSG00000025013, Tll2, tolloid-like 2, [Score=123, Expect=2e-31]} {Dmel: FBgn0028949, CG15254, [RH, Score=162, Expect=4e-49]} {Celegans: WBGene00003533, nas-14, Zinc metalloproteinase nas-14, [RH, Score=126, Expect=2e-33]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=106, Expect=3e-26]} {RNA1509_11696, RNA1509_13473, RNA1509_31566} {RNA1310_38053, RNA1509_11696, RNA1509_13473, RNA1509_31566} {RNA1509_11696, RNA1509_13473, RNA1509_31566, RNA815_18366.1}
50. MligTC455_43894 928 19.34 Mlig455_020079

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.895

Region-enriched R3: 2.909/0.00942

PLA2G15 2.535 0.868 - - 0.953 0.714 - Mlig455_020079 {REF} {Length: 1519} {Pfam: Lecithin:cholesterol acyltransferase [PF02450.17, score=205.7]; Alpha/beta hydrolase family [PF12697.9, score=27.5]; Serine hydrolase [PF06821.15, score=21.3]; Serine aminopeptidase, S33 [PF12146.10, score=18.9]} {Human: ENSG00000103066, PLA2G15, phospholipase A2 group XV, [Score=256, Expect=2e-81]} {Mouse: ENSMUSG00000031903, Pla2g15, phospholipase A2, group XV, [Score=236, Expect=1e-73]; ENSMUSG00000035237, Lcat, lecithin cholesterol acyltransferase, [Score=230, Expect=6e-71]} {Dmel: FBgn0042175, CG18858, [Score=229, Expect=4e-71]} {Celegans: WBGene00010872, M05B5.4, [RH, Score=277, Expect=1e-89]} {Smed: dd_Smed_v6_8328_0_1, dd_Smed_v6_8328_0_1, [RH, Score=257, Expect=2e-82]} {RNA1509_858} {RNA1310_22091, RNA1509_858} {RNA1509_858, RNA815_9147}
51. MligTC455_26524 420 8.74 Mlig455_036886

Neo: -

Age: Down-Down-Up

Region-enriched R3: 3.267/0.00000

CLCA4 2.47 0.775 - - 0.970 - 0.725 Mlig455_036886 {REF} {Length: 4324} {Pfam: von Willebrand factor type A domain [PF13519.8, score=51.6]; von Willebrand factor type A domain [PF00092.30, score=37.9]; von Willebrand factor type A domain [PF13768.8, score=32.9]; Calcium-activated chloride channel N terminal [PF08434.13, score=30.8]; VWA domain containing CoxE-like protein [PF05762.16, score=21.4]} {Human: ENSG00000016602, CLCA4, chloride channel accessory 4, [Score=153, Expect=2e-37]} {Mouse: ENSMUSG00000068547, Clca4a, chloride channel accessory 4A, [Score=148, Expect=4e-36]; ENSMUSG00000037033, Clca3b, chloride channel accessory 3B, [Score=142, Expect=5e-34]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [Score=114, Expect=1e-25]} {RNA1509_19436, RNA1509_49943} {RNA1310_3057, RNA1509_19436, RNA1509_49943} {RNA1509_19436, RNA1509_49943, RNA815_1871}
52. MligTC455_40546 1852 38.59 Mlig455_008147, Mlig455_055342

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.367/0.00122

2.453 0.714 - - 0.957 0.782 -

Mlig455_008147 {REF} {Length: 1732} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=40.2]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=38.9]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=22.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=21.3]; FAD binding domain [PF01494.21, score=19.7]} {RNA1509_13298, RNA1509_14537} {RNA1310_17901, RNA1509_14537} {RNA1509_14537, RNA815_2201}

Mlig455_055342 {REF} {Length: 1851} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=40.4]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=38.9]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=22.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=22.4]; FAD binding domain [PF01494.21, score=19.7]} {RNA1509_13298} {RNA1310_17901, RNA1509_13298} {RNA1509_13298, RNA815_2201}
53. MligTC455_20603 86 1.79 Mlig455_056482

Neo: -

Age: -

Region-enriched R4: 3.639/0.00787

2.439 - 0.714 - 0.972 0.753 - Mlig455_056482 {REF} {Length: 3315} {RNA1509_39269} {RNA1310_26481} {RNA815_10967.1}
54. MligTC455_51132 25223 525.48 Mlig455_048208

Neo: -

Age: Down-Up-Up

Region-enriched R3: 2.772/0.00000
Region-enriched R4: 1.680/0.03827

1.837 0.960 0.877 - - - - Mlig455_048208 {REF} {Length: 1734} {Pfam: Glycosyl hydrolases family 16 [PF00722.23, score=60.7]; Carbohydrate binding domain (family 32) [PF15886.7, score=40.4]} {Dmel: FBgn0040323, GNBP1, Gram-negative bacteria binding protein 1, [RH, Score=163, Expect=3e-44]} {RNA1509_1713, RNA1509_36676} {RNA1310_18175.1, RNA1509_1713, RNA1509_36676} {RNA1509_1713, RNA1509_36676, RNA815_10892.1}
55. MligTC455_40064 79 1.64 Mlig455_002594

Neo: Neoblast

Age: logFC(26M/2M)=-0.725

Region-enriched R4: 2.735/0.03778

ZFP36L2 1.828 - - - 0.874 - 0.954 Mlig455_002594 {REF} {Length: 1570} {Pfam: Zinc finger C-x8-C-x5-C-x3-H type (and similar) [PF00642.26, score=45.2]; Zinc finger domain [PF18345.3, score=34.4]; RNA-binding, Nab2-type zinc finger [PF14608.8, score=19.8]; CCCH-type zinc finger [PF18044.3, score=18.5]} {Human: ENSG00000152518, ZFP36L2, ZFP36 ring finger protein like 2, [RH, Score=76.6, Expect=4e-17]} {Mouse: ENSMUSG00000045817, Zfp36l2, zinc finger protein 36, C3H type-like 2, [Score=77.0, Expect=2e-17]; ENSMUSG00000021127, Zfp36l1, zinc finger protein 36, C3H type-like 1, [Score=77.0, Expect=1e-17]; ENSMUSG00000059334, Zfp36l3, zinc finger protein 36, C3H type-like 3, [Score=75.5, Expect=9e-17]} {Dmel: FBgn0011837, Tis11, Tis11 zinc finger protein, [Score=73.6, Expect=2e-16]} {Celegans: WBGene00009532, ccch-1, CCCH-type zinc finger putative transcription factor, [Score=70.1, Expect=3e-15]} {RNA1310_36065} {RNA815_47496}
56. MligTC455_55344 1399 29.15 Mlig455_011394

Neo: -

Age: -

1.774 - - - 0.989 0.785 - Mlig455_011394 {REF} {Length: 12} {NoTransDecoderORF}
57. MligTC455_33611 478 9.95 Mlig455_034367

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=1.080

Region-enriched R4: 2.761/0.00774
Region-enriched R3: 2.079/0.04141

ASAH2 1.686 - - - 0.961 - 0.725 Mlig455_034367 {REF} {Length: 2561} {Pfam: Neutral/alkaline non-lysosomal ceramidase, N-terminal [PF04734.15, score=706.1]; Neutral/alkaline non-lysosomal ceramidase, C-terminal [PF17048.7, score=154.5]} {Human: ENSG00000188611, ASAH2, N-acylsphingosine amidohydrolase 2, [RH, Score=627, Expect=0.0]} {Mouse: ENSMUSG00000024887, Asah2, N-acylsphingosine amidohydrolase 2, [RH, Score=614, Expect=0.0]} {Dmel: FBgn0039774, CDase, Ceramidase, [RH, Score=597, Expect=0.0]} {Smed: dd_Smed_v6_1726_0_1, dd_Smed_v6_1726_0_1, [RH, Score=662, Expect=0.0]} {RNA1509_4146} {RNA1310_8395.1} {RNA815_2759}
58. MligTC455_15196 47 0.97 Mlig455_005312

Neo: -

Age: -

0.973 - - - 0.973 - - Mlig455_005312 {REF} {Length: 5287} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=23.8]} {RNA1509_52065} {RNA1310_20362} {RNA815_22721}
59. MligTC455_22148 59 1.24 Mlig455_054943

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.887

XDH 0.971 - - - - - 0.971 Mlig455_054943 {REF} {Length: 5663} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=363.8]; EF-hand domain pair [PF13499.8, score=113.4]; EF hand [PF00036.34, score=108.8]; [2Fe-2S] binding domain [PF01799.22, score=95.7]; EF-hand domain [PF13405.8, score=88.2]; EF-hand domain pair [PF13833.8, score=75.8]; EF hand [PF13202.8, score=73.1]; EF-hand domain [PF14658.8, score=47.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=23.1]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=21.0]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=260, Expect=2e-70]; ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=249, Expect=7e-67]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=273, Expect=9e-75]} {Dmel: FBgn0038349, AOX3, Aldehyde oxidase 3, [Score=284, Expect=1e-78]} {Celegans: WBGene00010083, xhd-1, [Score=268, Expect=3e-73]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=155, Expect=1e-43]} {RNA1509_5953} {RNA1310_14932} {RNA815_18862}
60. MligTC455_10172 8 0.16 Mlig455_045782

Neo: -

Age: Up-Down-Down

0.97 - - - 0.970 - - Mlig455_045782 {REF} {Length: 4266} {Pfam: Aspartyl protease [PF13650.8, score=21.5]} {Smed: dd_Smed_v6_15720_0_1, dd_Smed_v6_15720_0_1, [Score=81.3, Expect=7e-18]} {RNA1509_44742} {RNA1310_15072} {RNA815_39341}
61. MligTC455_29781 66 1.38 Mlig455_061018

Neo: -

Age: -

TLR9 0.968 - - - 0.968 - - Mlig455_061018 {REF} {Length: 8473} {Pfam: Leucine rich repeat [PF13855.8, score=86.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=35.9]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=28.4]} {Human: ENSG00000239732, TLR9, toll like receptor 9, [Score=52.8, Expect=9e-06]; ENSG00000173366, AC097637.1, novel twinfilin, actin-binding protein, homolog 2 (Drosophila) (TWF2) and toll-like receptor 9 (TLR9) protein, [Score=52.8, Expect=9e-06]} {Mouse: ENSMUSG00000020105, Lrig3, leucine-rich repeats and immunoglobulin-like domains 3, [Score=52.4, Expect=1e-05]} {Dmel: FBgn0035575, CG7509, [Score=60.1, Expect=2e-08]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=72.4, Expect=4e-12]} {RNA1509_13450} {RNA1310_4749.1} {RNA815_668}
62. MligTC455_18814 44 0.91 Mlig455_001664

Neo: -

Age: Up-Down-Up

0.962 - - - 0.962 - - Mlig455_001664 {REF} {Length: 1673} {Smed: dd_Smed_v6_18585_0_1, dd_Smed_v6_18585_0_1, [Score=100, Expect=1e-23]} {RNA1310_49005} {RNA815_48672}
63. MligTC455_10165 180 3.75 Mlig455_010194, Mlig455_058694

Neo: Germline

Age: Up-Down-Down

Region-specific R4: 6.661

Region-enriched R4: 3.345/0.03003

0.961 - - - 0.961 - -

Mlig455_010194 {REF} {Length: 1334} {RNA1509_33844} {RNA1310_50327} {RNA815_17489}

Mlig455_058694 {REF} {Length: 1370} {RNA1509_33844, RNA1509_41444} {RNA1310_50327, RNA1509_33844, RNA1509_41444} {RNA1509_33844, RNA1509_41444, RNA815_17489}
64. MligTC455_17905 18 0.38 Mlig455_041409

Neo: -

Age: -

0.957 - - - 0.957 - - Mlig455_041409 {REF} {Length: 1032} {RNA1310_47367}
65. MligTC455_03852 16 0.33 Mlig455_003370

Neo: -

Age: Up-Down-Up

SLC26A6 0.956 - - - - - 0.956 Mlig455_003370 {REF} {Length: 2229} {Pfam: Sulfate permease family [PF00916.22, score=288.5]} {Human: ENSG00000225697, SLC26A6, solute carrier family 26 member 6, [Score=242, Expect=4e-70]; ENSG00000091137, SLC26A4, solute carrier family 26 member 4, [Score=241, Expect=2e-69]; ENSG00000170615, SLC26A5, solute carrier family 26 member 5, [Score=239, Expect=6e-71]; ENSG00000147606, SLC26A7, solute carrier family 26 member 7, [Score=233, Expect=2e-67]} {Mouse: ENSMUSG00000034320, Slc26a2, solute carrier family 26 (sulfate transporter), member 2, [Score=253, Expect=2e-74]; ENSMUSG00000023259, Slc26a6, solute carrier family 26, member 6, [Score=251, Expect=8e-75]; ENSMUSG00000107138, Slc26a6, solute carrier family 26, member 6, [Score=251, Expect=8e-75]} {Dmel: FBgn0036770, Prestin, [Score=221, Expect=1e-62]} {Celegans: WBGene00013963, sulp-8, Anion transporter SULP-8a; Anion transporter SULP-8b; SULfate Permease family, [Score=248, Expect=8e-74]} {Smed: dd_Smed_v6_16869_0_1, dd_Smed_v6_16869_0_1, [Score=348, Expect=2e-113]} {RNA1509_42083} {RNA1310_15401} {RNA815_12837}
66. MligTC455_45468 69 1.45 Mlig455_060264

Neo: -

Age: -

SLC16A14 0.954 - - - 0.954 - - Mlig455_060264 {REF} {Length: 2794} {Pfam: Major Facilitator Superfamily [PF07690.18, score=127.9]; Uncharacterised MFS-type transporter YbfB [PF06779.16, score=28.6]} {Human: ENSG00000163053, SLC16A14, solute carrier family 16 member 14, [Score=141, Expect=2e-35]} {Mouse: ENSMUSG00000026220, Slc16a14, solute carrier family 16 (monocarboxylic acid transporters), member 14, [Score=138, Expect=2e-34]} {Dmel: FBgn0035173, CG13907, [Score=287, Expect=8e-86]} {Celegans: WBGene00003986, mct-4, MonoCarboxylate Transporter family, [RH, Score=290, Expect=1e-87]} {Smed: dd_Smed_v6_10683_0_1, dd_Smed_v6_10683_0_1, [Score=206, Expect=2e-57]} {RNA1509_28783} {RNA1310_11981} {RNA815_32543}
67. MligTC455_45469 69 1.44 Mlig455_060274

Neo: -

Age: logFC(26M/2M)=0.506

SLC16A14 0.954 - - - 0.954 - - Mlig455_060274 {REF} {Length: 2378} {Pfam: Major Facilitator Superfamily [PF07690.18, score=82.2]} {Human: ENSG00000163053, SLC16A14, solute carrier family 16 member 14, [Score=139, Expect=7e-35]} {Mouse: ENSMUSG00000026220, Slc16a14, solute carrier family 16 (monocarboxylic acid transporters), member 14, [Score=136, Expect=8e-34]} {Dmel: FBgn0035173, CG13907, [Score=201, Expect=3e-55]} {Celegans: WBGene00003986, mct-4, MonoCarboxylate Transporter family, [Score=173, Expect=1e-45]} {Smed: dd_Smed_v6_9402_0_1, dd_Smed_v6_9402_0_1, [Score=145, Expect=7e-37]} {RNA1509_28783} {RNA1310_11981} {RNA815_32543}
68. MligTC455_52518 11 0.24 Mlig455_018171

Neo: -

Age: -

0.954 - - - 0.954 - - Mlig455_018171 {REF} {Length: 2652} {Smed: dd_Smed_v6_18585_0_1, dd_Smed_v6_18585_0_1, [Score=108, Expect=1e-26]} {RNA1310_62434} {RNA815_37083}
69. MligTC455_30398 332 6.92 Mlig455_029585, Mlig455_029606, Mlig455_061517

Neo: -

Age: -

Region-enriched R4: 5.143/0.00000

0.951 - - - - - 0.951

Mlig455_029585 {REF} {Length: 1248} {RNA1310_21610.1} {RNA815_16631}

Mlig455_029606 {REF} {Length: 1243} {RNA1310_21610.1} {RNA815_16631}

Mlig455_061517 {REF} {Length: 1435} {RNA1310_21610.1} {RNA815_16631}
70. MligTC455_16611 60 1.24 Mlig455_056028

Neo: Irradiation

Age: Up-Down-Down

Region-enriched R4: 5.455/0.00196

0.95 - - - 0.950 - - Mlig455_056028 {REF} {Length: 2245} {RNA1509_30958, RNA1509_4419, RNA1509_44911, RNA1509_45307, RNA1509_8207} {RNA1310_17568, RNA1509_30958, RNA1509_4419, RNA1509_44911, RNA1509_45307, RNA1509_8207} {RNA1509_30958, RNA1509_4419, RNA1509_44911, RNA1509_45307, RNA1509_8207, RNA815_7637}

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