M. lignano Tomo-Seq
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Results for MligTC455_22273

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_22273 1312 27.33 Mlig455_037142

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.517

 PKM Mlig455_037142 {REF} {Length: 2476} {TRANSSPLICED} {Pfam: Pyruvate kinase, barrel domain [PF00224.23, score=532.2]; Pyruvate kinase, alpha/beta domain [PF02887.18, score=107.6]; HpcH/HpaI aldolase/citrate lyase family [PF03328.16, score=22.4]} {Human: ENSG00000067225, PKM, pyruvate kinase M1/2, [RH, Score=702, Expect=0.0]; ENSG00000143627, PKLR, pyruvate kinase L/R, [RH, Score=670, Expect=0.0]; ENSG00000262785, PKLR, pyruvate kinase L/R, [RH, Score=670, Expect=0.0]} {Mouse: ENSMUSG00000032294, Pkm, pyruvate kinase, muscle, [RH, Score=700, Expect=0.0]} {Dmel: FBgn0267385, PyK, Pyruvate kinase, [RH, Score=661, Expect=0.0]} {Celegans: WBGene00009126, pyk-1, Pyruvate kinase, [RH, Score=641, Expect=0.0]} {Smed: dd_Smed_v6_605_0_1, dd_Smed_v6_605_0_1, [RH, Score=770, Expect=0.0]} {RNA1509_25980, RNA1509_32740} {RNA1310_7731.1, RNA1509_25980} {RNA1509_25980, RNA815_3516.1}

Cumulative graph for MligTC455_22273

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.616 5.04 0.16229 0.78472
RegionR2 0.388 5.04 0.51205 0.88947
RegionR3 0.783 5.04 0.09000 0.52985
RegionR4 0.282 5.04 0.61042 0.92168
RegionR5 0.997 5.04 0.02001 0.09712
RegionR6 0.397 5.04 0.41179 0.98088
RegionR7 -0.976 5.04 0.09752 0.59770
RegionR8 -0.256 5.04 0.69298 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.803 5.04 0.21038 0.95020
RegenerationR2 -0.226 5.04 0.69898 0.95602
RegenerationR3 -0.204 5.04 0.74158 0.96144
RegenerationR4 0.077 5.04 0.90267 1.00000
RegenerationR5 0.362 5.04 0.53741 0.87823
RegenerationR6 0.202 5.04 0.73042 0.94117
RegenerationBL 0.863 5.04 0.13254 0.43375
RegenerationTP 0.806 5.04 0.22811 0.67319


Genes with expression patterns similar to MligTC455_22273

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_22273 1312 27.33 Mlig455_037142

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.517

 PKM 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_037142 {REF} {Length: 2476} {TRANSSPLICED} {Pfam: Pyruvate kinase, barrel domain [PF00224.23, score=532.2]; Pyruvate kinase, alpha/beta domain [PF02887.18, score=107.6]; HpcH/HpaI aldolase/citrate lyase family [PF03328.16, score=22.4]} {Human: ENSG00000067225, PKM, pyruvate kinase M1/2, [RH, Score=702, Expect=0.0]; ENSG00000143627, PKLR, pyruvate kinase L/R, [RH, Score=670, Expect=0.0]; ENSG00000262785, PKLR, pyruvate kinase L/R, [RH, Score=670, Expect=0.0]} {Mouse: ENSMUSG00000032294, Pkm, pyruvate kinase, muscle, [RH, Score=700, Expect=0.0]} {Dmel: FBgn0267385, PyK, Pyruvate kinase, [RH, Score=661, Expect=0.0]} {Celegans: WBGene00009126, pyk-1, Pyruvate kinase, [RH, Score=641, Expect=0.0]} {Smed: dd_Smed_v6_605_0_1, dd_Smed_v6_605_0_1, [RH, Score=770, Expect=0.0]} {RNA1509_25980, RNA1509_32740} {RNA1310_7731.1, RNA1509_25980} {RNA1509_25980, RNA815_3516.1}
2. MligTC455_22274 2011 41.9 Mlig455_038507

Neo: -

Age: logFC(26M/2M)=0.411

Region-enriched R5: 1.184/0.00316

 PKM 4.244 0.999 0.863 0.725 0.852 - 0.805 Mlig455_038507 {REF} {Length: 2462} {TRANSSPLICED} {Pfam: Pyruvate kinase, barrel domain [PF00224.23, score=532.2]; Pyruvate kinase, alpha/beta domain [PF02887.18, score=107.6]; HpcH/HpaI aldolase/citrate lyase family [PF03328.16, score=22.4]} {Human: ENSG00000067225, PKM, pyruvate kinase M1/2, [RH, Score=702, Expect=0.0]; ENSG00000143627, PKLR, pyruvate kinase L/R, [RH, Score=670, Expect=0.0]; ENSG00000262785, PKLR, pyruvate kinase L/R, [RH, Score=670, Expect=0.0]} {Mouse: ENSMUSG00000032294, Pkm, pyruvate kinase, muscle, [RH, Score=700, Expect=0.0]} {Dmel: FBgn0267385, PyK, Pyruvate kinase, [RH, Score=661, Expect=0.0]} {Celegans: WBGene00009126, pyk-1, Pyruvate kinase, [RH, Score=641, Expect=0.0]} {Smed: dd_Smed_v6_605_0_1, dd_Smed_v6_605_0_1, [RH, Score=770, Expect=0.0]} {RNA1509_13634, RNA1509_1681, RNA1509_32740} {RNA1310_7731.1, RNA1509_13634, RNA1509_1681, RNA1509_32740} {RNA1509_13634, RNA1509_1681, RNA1509_32740, RNA815_3516.1}
3. MligTC455_29460 1052 21.93 Mlig455_052419

Neo: Int S/G2/M

Age: Down-Up-Down

Region-enriched R4: 2.228/0.01393
Region-enriched R5: 2.088/0.00325

 MSRB2 1.73 - 0.778 - - - 0.952 Mlig455_052419 {REF} {Length: 908} {TRANSSPLICED} {Pfam: SelR domain [PF01641.20, score=159.0]} {Human: ENSG00000148450, MSRB2, methionine sulfoxide reductase B2, [Score=134, Expect=4e-39]} {Mouse: ENSMUSG00000023094, Msrb2, methionine sulfoxide reductase B2, [Score=133, Expect=5e-39]} {Dmel: FBgn0267376, SelR, Selenoprotein R, [Score=119, Expect=6e-34]} {Celegans: WBGene00018419, F44E2.6, [Score=143, Expect=9e-44]} {Smed: dd_Smed_v6_1344_0_1, dd_Smed_v6_1344_0_1, [Score=116, Expect=2e-33]} {RNA1509_56840} {RNA1310_38779} {RNA815_18708}
4. MligTC455_50753 842 17.55 Mlig455_030625, Mlig455_030697, Mlig455_031018

Neo: -

Age: Up-Down-Down

 1.683 - - - 0.723 - 0.960

Mlig455_030625 {REF} {Length: 1981} {TRANSSPLICED} {Pfam: TIR domain [PF13676.8, score=55.3]; TIR domain [PF01582.22, score=20.1]} {RNA1509_23304, RNA1509_39929} {RNA1310_30342, RNA1509_39929} {RNA1509_39929, RNA815_30652}

Mlig455_030697 {REF} {Length: 2059} {TRANSSPLICED} {Pfam: TIR domain [PF13676.8, score=55.3]; TIR domain [PF01582.22, score=20.1]} {RNA1509_23304} {RNA1310_30342, RNA1509_23304} {RNA1509_23304, RNA815_30652}

Mlig455_031018 {REF} {Length: 2064} {TRANSSPLICED} {Pfam: TIR domain [PF13676.8, score=55.4]; TIR domain [PF01582.22, score=20.1]} {RNA1509_23304} {RNA1310_30342} {RNA815_30652}
5. MligTC455_48004 1344 28 Mlig455_066992

Neo: Int S/G2/M

Age: -

Region-enriched R4: 1.172/0.00763

 PSMD2 0.968 - - - - - 0.968 Mlig455_066992 {REF} {Length: 4622} {Pfam: RPN1 N-terminal domain [PF17781.3, score=363.0]; 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal [PF18051.3, score=105.9]; Proteasome/cyclosome repeat [PF01851.24, score=61.4]} {Human: ENSG00000175166, PSMD2, proteasome 26S subunit, non-ATPase 2, [RH, Score=902, Expect=0.0]} {Mouse: ENSMUSG00000006998, Psmd2, proteasome (prosome, macropain) 26S subunit, non-ATPase, 2, [RH, Score=897, Expect=0.0]} {Dmel: FBgn0028695, Rpn1, Regulatory particle non-ATPase 1, [RH, Score=837, Expect=0.0]} {Celegans: WBGene00004458, rpn-1, Proteasome Regulatory Particle, Non-ATPase-like, [RH, Score=809, Expect=0.0]} {Smed: dd_Smed_v6_2481_0_1, dd_Smed_v6_2481_0_1, [RH, Score=950, Expect=0.0]} {RNA1509_1075, RNA1509_29705} {RNA1310_3428, RNA1509_1075, RNA1509_29705} {RNA1509_1075, RNA1509_29705, RNA815_1690}
6. MligTC455_40113 1364 28.42 Mlig455_050174

Neo: -

Age: Down-Up-Up

 DNAJC21 0.957 - - - - - 0.957 Mlig455_050174 {REF} {Length: 3708} {TRANSSPLICED} {Pfam: DnaJ domain [PF00226.33, score=158.2]; C2H2 type zinc-finger (2 copies) [PF12756.9, score=28.0]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=22.6]; Zinc-finger of C2H2 type [PF12874.9, score=21.3]; C2H2-type zinc finger [PF13894.8, score=19.4]; Protein of unknown function (DUF2778) [PF10908.10, score=19.0]} {Human: ENSG00000168724, DNAJC21, DnaJ heat shock protein family (Hsp40) member C21, [Score=320, Expect=2e-98]} {Mouse: ENSMUSG00000044224, Dnajc21, DnaJ heat shock protein family (Hsp40) member C21, [RH, Score=317, Expect=1e-97]} {Dmel: FBgn0027599, CG2790, [RH, Score=292, Expect=2e-88]} {Celegans: WBGene00001035, dnj-17, DNaJ domain (Prokaryotic heat shock protein), [Score=142, Expect=7e-36]} {Smed: dd_Smed_v6_5775_0_1, dd_Smed_v6_5775_0_1, [Score=253, Expect=2e-74]} {RNA1509_5192} {RNA1310_14822} {RNA815_6329}

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