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Results for MligTC455_22594

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_22594 11907 248.06 Mlig455_000659

Neo: -

Age: -

Region-enriched R3: 1.649/0.00345
Region-enriched R6: 1.411/0.04025
Region-enriched R5: 1.370/0.00986

FTH1 Mlig455_000659 {REF} {Length: 4971} {Pfam: Ferritin-like domain [PF00210.26, score=121.4]; Rubrerythrin [PF02915.19, score=26.2]} {Human: ENSG00000167996, FTH1, ferritin heavy chain 1, [Score=131, Expect=3e-38]} {Mouse: ENSMUSG00000024661, Fth1, ferritin heavy polypeptide 1, [Score=127, Expect=4e-37]; ENSMUSG00000024510, Ftmt, ferritin mitochondrial, [Score=123, Expect=7e-35]} {Dmel: FBgn0030449, Fer3HCH, Ferritin 3 heavy chain homologue, [Score=127, Expect=4e-37]} {Celegans: WBGene00001501, ftn-2, Ferritin, [Score=134, Expect=5e-40]} {Smed: dd_Smed_v6_3974_0_1, dd_Smed_v6_3974_0_1, [Score=143, Expect=1e-43]} {RNA1509_1543, RNA1509_3403, RNA1509_3412, RNA1509_36561, RNA1509_39647, RNA1509_51397, RNA1509_5479} {RNA1310_294, RNA1509_1543, RNA1509_3403, RNA1509_3412, RNA1509_36561, RNA1509_39647, RNA1509_51397} {RNA1509_1543, RNA1509_3403, RNA1509_3412, RNA1509_36561, RNA1509_39647, RNA1509_51397, RNA815_755}

Cumulative graph for MligTC455_22594

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.018 8.062 0.97597 1.00000
RegionR2 -1.487 8.062 0.00698 0.08018
RegionR3 1.649 8.062 0.00007 0.00345
RegionR4 0.947 8.062 0.04818 0.18809
RegionR5 1.37 8.062 0.00096 0.00986
RegionR6 1.411 8.062 0.00107 0.04025
RegionR7 -2.019 8.062 0.00019 0.00963
RegionR8 -1.889 8.062 0.00134 0.05719

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.296 8.062 0.07461 0.76170
RegenerationR2 -0.343 8.062 0.56987 0.90229
RegenerationR3 -0.587 8.062 0.31926 0.74762
RegenerationR4 -0.178 8.062 0.76912 0.97656
RegenerationR5 -0.057 8.062 0.92320 1.00000
RegenerationR6 -0.694 8.062 0.24373 0.59173
RegenerationBL -0.546 8.062 0.30787 0.67257
RegenerationTP -0.186 8.062 0.74688 1.00000


Genes with expression patterns similar to MligTC455_22594

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_22594 11907 248.06 Mlig455_000659

Neo: -

Age: -

Region-enriched R3: 1.649/0.00345
Region-enriched R6: 1.411/0.04025
Region-enriched R5: 1.370/0.00986

FTH1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_000659 {REF} {Length: 4971} {Pfam: Ferritin-like domain [PF00210.26, score=121.4]; Rubrerythrin [PF02915.19, score=26.2]} {Human: ENSG00000167996, FTH1, ferritin heavy chain 1, [Score=131, Expect=3e-38]} {Mouse: ENSMUSG00000024661, Fth1, ferritin heavy polypeptide 1, [Score=127, Expect=4e-37]; ENSMUSG00000024510, Ftmt, ferritin mitochondrial, [Score=123, Expect=7e-35]} {Dmel: FBgn0030449, Fer3HCH, Ferritin 3 heavy chain homologue, [Score=127, Expect=4e-37]} {Celegans: WBGene00001501, ftn-2, Ferritin, [Score=134, Expect=5e-40]} {Smed: dd_Smed_v6_3974_0_1, dd_Smed_v6_3974_0_1, [Score=143, Expect=1e-43]} {RNA1509_1543, RNA1509_3403, RNA1509_3412, RNA1509_36561, RNA1509_39647, RNA1509_51397, RNA1509_5479} {RNA1310_294, RNA1509_1543, RNA1509_3403, RNA1509_3412, RNA1509_36561, RNA1509_39647, RNA1509_51397} {RNA1509_1543, RNA1509_3403, RNA1509_3412, RNA1509_36561, RNA1509_39647, RNA1509_51397, RNA815_755}
2. MligTC455_49488 5075 105.73 Mlig455_055474

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.341

Region-enriched R3: 1.609/0.02116

5.523 0.912 0.854 0.938 0.927 0.962 0.930 Mlig455_055474 {REF} {Length: 988} {Pfam: Universal stress protein family [PF00582.28, score=100.4]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=126, Expect=2e-37]} {RNA1509_12747, RNA1509_15238} {RNA1310_22621, RNA1509_15238} {RNA1509_15238, RNA815_17247}
3. MligTC455_49487 5068 105.57 Mlig455_036283

Neo: -

Age: logFC(26M/2M)=-0.424

Region-enriched R3: 1.606/0.02613

5.521 0.912 0.854 0.938 0.928 0.958 0.931 Mlig455_036283 {REF} {Length: 978} {Pfam: Universal stress protein family [PF00582.28, score=89.7]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=109, Expect=3e-31]} {RNA1509_12747} {RNA1310_22621} {RNA815_17247}
4. MligTC455_22268 6636 138.25 Mlig455_011760

Neo: -

Age: logFC(26M/2M)=-0.323

Region-enriched R3: 1.908/0.00000
Region-enriched R6: 1.283/0.01830
Region-enriched R5: 1.133/0.00963

5.498 0.911 0.926 0.909 0.911 0.875 0.966 Mlig455_011760 {REF} {Length: 2561} {RNA1509_1433} {RNA1310_8428, RNA1509_1433} {RNA1509_1433, RNA815_2971}
5. MligTC455_24091 3616 75.33 Mlig455_024205

Neo: -

Age: -

Region-enriched R3: 1.943/0.00049

5.435 0.916 0.888 0.819 0.945 0.899 0.968 Mlig455_024205 {REF} {Length: 3598} {Pfam: PAN domain [PF00024.28, score=45.6]} {RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529} {RNA1310_3811, RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529} {RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529, RNA815_1158.1}
6. MligTC455_54299 11737 244.53 Mlig455_002787

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.295

Region-enriched R3: 1.671/0.00015

Regeneration-depleted R3: -2.524
Regeneration-depleted R2: -2.294
Regeneration-depleted BL: -2.060

5.402 0.939 0.875 0.881 0.990 0.818 0.899 Mlig455_002787 {REF} {Length: 1113} {NoTransDecoderORF} {RNA1509_14219, RNA1509_1633, RNA1509_20378, RNA1509_22911, RNA1509_28687, RNA1509_5164, RNA1509_59041, RNA1509_6575} {RNA1310_41623.1, RNA1509_14219, RNA1509_1633, RNA1509_20378, RNA1509_22911, RNA1509_28687, RNA1509_5164, RNA1509_59041, RNA1509_6575} {RNA1509_14219, RNA1509_1633, RNA1509_20378, RNA1509_22911, RNA1509_28687, RNA1509_5164, RNA1509_59041, RNA1509_6575, RNA815_10359}
7. MligTC455_36240 5999 124.98 Mlig455_043113

Neo: -

Age: logFC(26M/2M)=0.402

EPHX4 5.399 0.893 0.790 0.801 0.975 0.976 0.964 Mlig455_043113 {REF} {Length: 2152} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=86.1]; Alpha/beta hydrolase family [PF12697.9, score=72.2]; Serine aminopeptidase, S33 [PF12146.10, score=55.9]; Ndr family [PF03096.16, score=20.5]} {Human: ENSG00000172031, EPHX4, epoxide hydrolase 4, [RH, Score=248, Expect=1e-78]} {Mouse: ENSMUSG00000033805, Ephx4, epoxide hydrolase 4, [RH, Score=237, Expect=1e-74]} {Dmel: FBgn0035951, CG5068, [Score=49.7, Expect=3e-06]} {Celegans: WBGene00019329, ceeh-1, Epoxide hydrolase 1, [RH, Score=228, Expect=1e-70]} {Smed: dd_Smed_v6_2011_0_1, dd_Smed_v6_2011_0_1, [RH, Score=252, Expect=8e-81]} {RNA1509_19687, RNA1509_20879, RNA1509_7823} {RNA1310_15717.1, RNA1509_19687, RNA1509_20879} {RNA1509_19687, RNA1509_20879, RNA815_5437.1}
8. MligTC455_35633 4966 103.45 Mlig455_048471

Neo: -

Age: -

Region-enriched R4: 1.579/0.00682
Region-enriched R3: 1.493/0.00762

DHDH 5.393 0.893 0.865 0.806 0.890 0.996 0.943 Mlig455_048471 {REF} {Length: 1491} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=87.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]; Homoserine dehydrogenase, NAD binding domain [PF03447.18, score=19.9]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=246, Expect=3e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=248, Expect=4e-80]} {Dmel: FBgn0031418, CG3609, [RH, Score=231, Expect=1e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=213, Expect=9e-67]} {RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1310_24236, RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1509_1049, RNA1509_4889, RNA1509_8979, RNA815_11111.1}
9. MligTC455_36239 5931 123.57 Mlig455_043102

Neo: -

Age: logFC(26M/2M)=0.673

EPHX4 5.383 0.886 0.791 0.798 0.975 0.974 0.959 Mlig455_043102 {REF} {Length: 1398} {Human: ENSG00000172031, EPHX4, epoxide hydrolase 4, [Score=120, Expect=5e-32]} {Mouse: ENSMUSG00000033805, Ephx4, epoxide hydrolase 4, [Score=107, Expect=2e-27]} {Celegans: WBGene00019329, ceeh-1, Epoxide hydrolase 1, [Score=103, Expect=5e-26]} {Smed: dd_Smed_v6_2011_0_1, dd_Smed_v6_2011_0_1, [Score=131, Expect=8e-37]} {RNA1509_7823} {RNA1310_15717.2} {RNA815_5437.1}
10. MligTC455_43334 7286 151.78 Mlig455_054088

Neo: -

Age: logFC(26M/2M)=0.327

Region-enriched R3: 1.908/0.00014

CTSB 5.377 0.952 0.864 0.911 0.781 0.950 0.919 Mlig455_054088 {REF} {Length: 2579} {Pfam: Papain family cysteine protease [PF00112.25, score=227.1]; Peptidase family C1 propeptide [PF08127.15, score=44.5]} {Human: ENSG00000164733, CTSB, cathepsin B, [RH, Score=387, Expect=1e-134]} {Mouse: ENSMUSG00000021939, Ctsb, cathepsin B, [RH, Score=387, Expect=1e-134]} {Dmel: FBgn0030521, CtsB1, Cathepsin B1, [RH, Score=369, Expect=2e-127]} {Celegans: WBGene00010204, F57F5.1, [RH, Score=338, Expect=1e-115]} {Smed: dd_Smed_v6_81_0_1, dd_Smed_v6_81_0_1, [RH, Score=424, Expect=2e-149]} {RNA1509_448} {RNA1310_24539, RNA1509_448} {RNA1509_448, RNA815_4531}
11. MligTC455_24859 5590 116.45 Mlig455_054066, Mlig455_063284

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.306

Region-enriched R3: 2.202/0.00434

5.37 0.876 0.877 0.881 0.956 0.841 0.939

Mlig455_054066 {REF} {Length: 1406} {RNA1509_33411, RNA1509_7753} {RNA1310_22791, RNA1509_33411} {RNA1509_33411, RNA815_10514.1}

Mlig455_063284 {REF} {Length: 1414} {Pfam: Multi-glycosylated core protein 24 (MGC-24), sialomucin [PF05283.13, score=46.5]} {Mouse: ENSMUSG00000050912, Tmem123, transmembrane protein 123, [Score=46.6, Expect=2e-06]} {Dmel: FBgn0045823, vsg, visgun, [Score=53.1, Expect=8e-09]} {Smed: dd_Smed_v6_828_0_1, dd_Smed_v6_828_0_1, [RH, Score=53.5, Expect=2e-10]} {RNA1509_7753} {RNA1310_22791} {RNA815_10514.1}
12. MligTC455_16085 3839 79.98 Mlig455_044272

Neo: -

Age: -

Region-enriched R3: 2.086/0.00013
Region-enriched R5: 1.156/0.04710

5.342 0.858 0.835 0.870 0.957 0.928 0.894 Mlig455_044272 {REF} {Length: 2367} {Pfam: Innexin [PF00876.20, score=380.9]} {Dmel: FBgn0265274, Inx3, Innexin 3, [Score=112, Expect=4e-27]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=327, Expect=2e-109]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [RH, Score=326, Expect=1e-108]} {RNA1509_1749, RNA1509_24186} {RNA1310_9598.1, RNA1509_1749, RNA1509_24186} {RNA1509_1749, RNA1509_24186, RNA815_7866}
13. MligTC455_39701 17128 356.84 Mlig455_024199

Neo: -

Age: -

Region-enriched R5: 1.162/0.00285
Region-enriched R6: 1.161/0.01930
Region-enriched R3: 1.136/0.01406

TSPO 5.34 0.957 0.842 0.897 0.964 0.893 0.787 Mlig455_024199 {REF} {Length: 850} {TRANSSPLICED} {Pfam: TspO/MBR family [PF03073.17, score=150.0]} {Human: ENSG00000100300, TSPO, translocator protein, [Score=110, Expect=2e-30]} {Mouse: ENSMUSG00000041736, Tspo, translocator protein, [Score=111, Expect=8e-31]} {Dmel: FBgn0031263, Tspo, Translocator protein, [Score=127, Expect=5e-37]} {Smed: dd_Smed_v6_607_1_1, dd_Smed_v6_607_1_1, [Score=102, Expect=6e-28]} {RNA1509_21755, RNA1509_23760, RNA1509_2493, RNA1509_2803, RNA1509_2847, RNA1509_33685, RNA1509_33719, RNA1509_44951, RNA1509_5242, RNA1509_8186, RNA1509_9255} {RNA1310_41806, RNA1509_21755, RNA1509_23760, RNA1509_2493, RNA1509_2803, RNA1509_2847, RNA1509_33685, RNA1509_33719, RNA1509_44951, RNA1509_5242, RNA1509_8186, RNA1509_9255} {RNA1509_21755, RNA1509_23760, RNA1509_2493, RNA1509_2803, RNA1509_2847, RNA1509_33685, RNA1509_33719, RNA1509_44951, RNA1509_5242, RNA1509_8186, RNA1509_9255, RNA815_4590.1}
14. MligTC455_46304 5253 109.45 Mlig455_047938

Neo: -

Age: -

Region-enriched R4: 1.799/0.00000
Region-enriched R3: 1.541/0.00001
Region-enriched R5: 1.139/0.00155

MGST1 5.314 0.899 0.824 0.785 0.923 0.928 0.955 Mlig455_047938 {REF} {Length: 721} {TRANSSPLICED} {Pfam: MAPEG family [PF01124.20, score=74.9]} {Human: ENSG00000008394, MGST1, microsomal glutathione S-transferase 1, [RH, Score=146, Expect=2e-45]} {Mouse: ENSMUSG00000008540, Mgst1, microsomal glutathione S-transferase 1, [RH, Score=150, Expect=3e-47]} {Dmel: FBgn0025814, Mgstl, Microsomal glutathione S-transferase-like, [RH, Score=127, Expect=5e-38]} {RNA1509_13231, RNA1509_3817, RNA1509_42261, RNA1509_45247, RNA1509_47449, RNA1509_7161, RNA1509_9208} {RNA1310_49001.1, RNA1509_13231, RNA1509_3817, RNA1509_42261, RNA1509_45247, RNA1509_47449, RNA1509_7161, RNA1509_9208} {RNA1509_13231, RNA1509_3817, RNA1509_42261, RNA1509_45247, RNA1509_47449, RNA1509_7161, RNA1509_9208, RNA815_18438}
15. MligTC455_33577 18072 376.49 Mlig455_043957, Mlig455_043969, Mlig455_044039

Neo: -

Age: logFC(26M/2M)=0.423

Region-enriched R5: 1.425/0.00134
Region-enriched R4: 1.282/0.02044

IDH1 5.303 0.869 0.711 0.899 0.958 0.967 0.899

Mlig455_043957 {REF} {Length: 2414} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=266.7]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=664, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=660, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=636, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=651, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=652, Expect=0.0]} {RNA1509_16912} {RNA1310_10691.1, RNA1509_16912} {RNA1509_16912, RNA815_3934}

Mlig455_043969 {REF} {Length: 2413} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=267.0]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=667, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=639, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=654, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=655, Expect=0.0]} {RNA1509_16912, RNA1509_26642, RNA1509_847} {RNA1310_10691.1, RNA1509_26642, RNA1509_847} {RNA1509_26642, RNA1509_847, RNA815_3934}

Mlig455_044039 {REF} {Length: 2905} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=267.0]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=667, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=639, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=654, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=655, Expect=0.0]} {RNA1509_16912, RNA1509_38467} {RNA1310_10691.1, RNA1509_38467} {RNA1509_38467, RNA815_3934}
16. MligTC455_37113 9210 191.88 Mlig455_020693

Neo: -

Age: -

Region-enriched R3: 1.525/0.00009

LGMN 5.288 0.870 0.787 0.842 0.946 0.890 0.953 Mlig455_020693 {REF} {Length: 3890} {Pfam: Peptidase C13 family [PF01650.20, score=361.0]} {Human: ENSG00000100600, LGMN, legumain, [RH, Score=382, Expect=2e-129]} {Mouse: ENSMUSG00000021190, Lgmn, legumain, [RH, Score=388, Expect=4e-132]} {Dmel: FBgn0023545, PIG-K, Phosphatidylinositol glycan anchor biosynthesis class K, [Score=127, Expect=1e-32]} {Celegans: WBGene00012144, T28H10.3, [RH, Score=327, Expect=7e-108]} {Smed: dd_Smed_v6_6456_0_1, dd_Smed_v6_6456_0_1, [Score=105, Expect=3e-25]} {RNA1509_312} {RNA1310_13933, RNA1509_312} {RNA1509_312, RNA815_6243.1}
17. MligTC455_41362 18978 395.37 Mlig455_060085

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.318

Region-enriched R6: 1.464/0.04128
Region-enriched R3: 1.440/0.02890

5.278 0.955 0.863 0.925 0.955 0.796 0.784 Mlig455_060085 {REF} {Length: 947} {Pfam: Type III secretion system lipoprotein chaperone (YscW) [PF09619.12, score=36.5]} {RNA1509_1561, RNA1509_8482} {RNA1310_44094, RNA1509_1561, RNA1509_8482} {RNA1509_1561, RNA1509_8482, RNA815_10777.1}
18. MligTC455_24086 11442 238.37 Mlig455_068330

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.329/0.00000
Region-enriched R6: 1.493/0.00384
Region-enriched R5: 1.266/0.00365

ACHE 5.277 0.921 0.778 0.860 0.891 0.953 0.874 Mlig455_068330 {REF} {Length: 2275} {Pfam: Carboxylesterase family [PF00135.30, score=340.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=228, Expect=5e-66]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=226, Expect=1e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=191, Expect=1e-52]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=226, Expect=1e-65]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=202, Expect=4e-57]} {RNA1509_2293, RNA1509_46106} {RNA1310_10437.1, RNA1509_2293} {RNA1509_2293, RNA815_3976}
19. MligTC455_23470 9172 191.09 Mlig455_028371

Neo: -

Age: logFC(26M/2M)=0.981

MAT1A 5.255 0.832 0.737 0.888 0.984 0.875 0.939 Mlig455_028371 {REF} {Length: 2297} {Pfam: S-adenosylmethionine synthetase, C-terminal domain [PF02773.18, score=222.1]; S-adenosylmethionine synthetase, central domain [PF02772.18, score=166.7]; S-adenosylmethionine synthetase, N-terminal domain [PF00438.22, score=145.8]} {Human: ENSG00000151224, MAT1A, methionine adenosyltransferase 1A, [RH, Score=581, Expect=0.0]; ENSG00000168906, MAT2A, methionine adenosyltransferase 2A, [RH, Score=577, Expect=0.0]} {Mouse: ENSMUSG00000037798, Mat1a, methionine adenosyltransferase I, alpha, [RH, Score=580, Expect=0.0]; ENSMUSG00000053907, Mat2a, methionine adenosyltransferase II, alpha, [RH, Score=577, Expect=0.0]; ENSMUSG00000104463, Mat2a, methionine adenosyltransferase II, alpha, [RH, Score=577, Expect=0.0]} {Dmel: FBgn0005278, Sam-S, S-adenosylmethionine Synthetase, [RH, Score=532, Expect=0.0]} {Celegans: WBGene00015538, sams-3, Probable S-adenosylmethionine synthase 3, [RH, Score=545, Expect=0.0]} {Smed: dd_Smed_v6_1580_0_1, dd_Smed_v6_1580_0_1, [RH, Score=617, Expect=0.0]} {RNA1509_1149, RNA1509_1300, RNA1509_18151} {RNA1310_9572, RNA1509_1149, RNA1509_1300, RNA1509_18151} {RNA1509_1149, RNA1509_1300, RNA1509_18151, RNA815_3897}
20. MligTC455_41984 5794 120.71 Mlig455_070257

Neo: -

Age: logFC(26M/2M)=0.384

Region-enriched R3: 1.830/0.00014
Region-enriched R4: 1.696/0.00265
Region-enriched R6: 1.511/0.01084
Region-enriched R5: 1.493/0.00157

BHMT 5.255 0.953 0.815 0.798 0.970 0.912 0.807 Mlig455_070257 {REF} {Length: 2300} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=161.5]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=543, Expect=0.0]} {Mouse: ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=548, Expect=0.0]; ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=548, Expect=0.0]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=555, Expect=0.0]} {RNA1509_10637, RNA1509_54311, RNA1509_9980} {RNA1310_18981.1, RNA1509_54311, RNA1509_9980} {RNA1509_54311, RNA1509_9980, RNA815_5900.2}
21. MligTC455_51431 4302 89.63 Mlig455_045755

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.984/0.00149
Region-enriched R5: 1.417/0.02239

5.226 0.799 0.751 0.967 0.931 0.874 0.904 Mlig455_045755 {REF} {Length: 312} {NoTransDecoderORF} {RNA1509_51873} {RNA1310_8784.1} {RNA815_3564}
22. MligTC455_46966 3276 68.25 Mlig455_063795

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.710

Region-enriched R4: 1.522/0.00004
Region-enriched R3: 1.339/0.00009
Region-enriched R5: 1.261/0.00005

BPNT1 5.221 0.820 0.835 0.803 0.971 0.891 0.901 Mlig455_063795 {REF} {Length: 2348} {TRANSSPLICED} {Pfam: Inositol monophosphatase family [PF00459.27, score=163.3]} {Human: ENSG00000162813, BPNT1, 3'(2'), 5'-bisphosphate nucleotidase 1, [RH, Score=290, Expect=2e-97]} {Mouse: ENSMUSG00000026617, Bpnt1, bisphosphate 3'-nucleotidase 1, [RH, Score=285, Expect=4e-95]} {Dmel: FBgn0039698, CG7789, [RH, Score=293, Expect=1e-98]} {Celegans: WBGene00044063, bpnt-1, 3'(2'), 5'-BisPhosphate NucleoTidase 1 homolog, [Score=198, Expect=2e-61]} {Smed: dd_Smed_v6_1334_0_1, dd_Smed_v6_1334_0_1, [RH, Score=307, Expect=2e-104]} {RNA1509_10672, RNA1509_12549, RNA1509_12797, RNA1509_28557, RNA1509_41058, RNA1509_46643, RNA1509_6484} {RNA1310_16422.1, RNA1509_10672, RNA1509_12549, RNA1509_12797, RNA1509_28557, RNA1509_41058, RNA1509_46643, RNA1509_6484} {RNA1509_10672, RNA1509_12549, RNA1509_12797, RNA1509_28557, RNA1509_41058, RNA1509_46643, RNA1509_6484, RNA815_6682}
23. MligTC455_37114 9548 198.91 Mlig455_020763

Neo: -

Age: -

Region-enriched R3: 1.051/0.01206

LGMN 5.214 0.869 0.742 0.920 0.936 0.773 0.974 Mlig455_020763 {REF} {Length: 1971} {Pfam: Peptidase C13 family [PF01650.20, score=360.1]} {Human: ENSG00000100600, LGMN, legumain, [RH, Score=386, Expect=4e-131]} {Mouse: ENSMUSG00000021190, Lgmn, legumain, [RH, Score=391, Expect=4e-133]} {Dmel: FBgn0023545, PIG-K, Phosphatidylinositol glycan anchor biosynthesis class K, [Score=126, Expect=2e-32]} {Celegans: WBGene00012144, T28H10.3, [RH, Score=323, Expect=2e-106]} {Smed: dd_Smed_v6_6456_0_1, dd_Smed_v6_6456_0_1, [Score=104, Expect=5e-25]} {RNA1509_4583} {RNA1310_13933, RNA1509_4583} {RNA1509_4583, RNA815_6243.1}
24. MligTC455_35652 9154 190.71 Mlig455_057115

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.261

Region-enriched R3: 1.585/0.00213
Region-enriched R5: 1.102/0.03479

CD82 5.214 0.738 0.782 0.916 0.968 0.893 0.917 Mlig455_057115 {REF} {Length: 1682} {Pfam: Tetraspanin family [PF00335.22, score=118.2]} {Human: ENSG00000085117, CD82, CD82 molecule, [Score=68.9, Expect=5e-13]} {Mouse: ENSMUSG00000030342, Cd9, CD9 antigen, [Score=73.2, Expect=7e-15]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [RH, Score=110, Expect=3e-28]} {Celegans: WBGene00006634, tsp-8, Tetraspanin, [Score=56.2, Expect=5e-09]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [Score=97.1, Expect=1e-23]} {RNA1509_13954, RNA1509_2691, RNA1509_27048, RNA1509_4769, RNA1509_58598, RNA1509_58951, RNA1509_9364, RNA1509_9911} {RNA1310_22327, RNA1509_13954, RNA1509_2691, RNA1509_27048, RNA1509_4769, RNA1509_58598, RNA1509_58951, RNA1509_9364, RNA1509_9911} {RNA1509_13954, RNA1509_2691, RNA1509_27048, RNA1509_4769, RNA1509_58598, RNA1509_58951, RNA1509_9364, RNA1509_9911, RNA815_10761}
25. MligTC455_48070 1559 32.49 Mlig455_019661

Neo: -

Age: logFC(26M/2M)=-0.328

Region-enriched R3: 1.615/0.01457

HSD11B1 5.206 0.876 0.859 0.834 0.832 0.850 0.955 Mlig455_019661 {REF} {Length: 1828} {Pfam: short chain dehydrogenase [PF00106.27, score=125.5]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=75.3]; KR domain [PF08659.12, score=27.1]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=157, Expect=2e-45]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=154, Expect=1e-44]} {Dmel: FBgn0027583, CG7601, [Score=82.0, Expect=1e-17]} {Celegans: WBGene00014093, ZK829.1, [Score=74.3, Expect=4e-15]} {Smed: dd_Smed_v6_3167_0_1, dd_Smed_v6_3167_0_1, [Score=62.8, Expect=2e-11]} {RNA1509_11335, RNA1509_15148} {RNA1310_26648, RNA1509_11335, RNA1509_15148} {RNA1509_11335, RNA1509_15148, RNA815_11342}
26. MligTC455_22269 4351 90.65 Mlig455_047974, Mlig455_066358

Neo: -

Age: logFC(26M/2M)=-0.280

Region-enriched R3: 1.530/0.00596
Region-enriched R5: 1.199/0.02282

5.203 0.825 0.874 0.709 0.957 0.915 0.923

Mlig455_047974 {REF} {Length: 2562} {RNA1509_1433} {RNA1310_8428} {RNA815_2971}

Mlig455_066358 {REF} {Length: 3293} {RNA1509_1433} {RNA1310_8428} {RNA815_2971}
27. MligTC455_20843 4495 93.65 Mlig455_019749

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.255

ATP1B1 5.196 0.924 0.718 0.864 0.966 0.828 0.896 Mlig455_019749 {REF} {Length: 1424} {TRANSSPLICED} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=213.7]} {Human: ENSG00000143153, ATP1B1, ATPase Na+/K+ transporting subunit beta 1, [Score=115, Expect=2e-29]} {Mouse: ENSMUSG00000026576, Atp1b1, ATPase, Na+/K+ transporting, beta 1 polypeptide, [Score=115, Expect=5e-30]} {Dmel: FBgn0032946, nrv3, nervana 3, [RH, Score=159, Expect=2e-46]} {Celegans: WBGene00010117, nkb-3, Probable sodium/potassium-transporting ATPase subunit beta-3, [RH, Score=174, Expect=3e-52]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [Score=198, Expect=4e-62]} {RNA1509_10586} {RNA1310_23188.1} {RNA815_9461}
28. MligTC455_18651 2559 53.32 Mlig455_067661

Neo: -

Age: -

Region-enriched R3: 1.583/0.04334

5.188 0.884 0.767 0.715 0.927 0.928 0.967 Mlig455_067661 {REF} {Length: 616} {RNA1509_2812} {RNA1310_3353.1, RNA1509_2812} {RNA1509_2812, RNA815_7653}
29. MligTC455_20842 4892 101.93 Mlig455_004914

Neo: -

Age: Down-Down-Up

ATP1B1 5.184 0.933 0.715 0.866 0.978 0.833 0.859 Mlig455_004914 {REF} {Length: 1421} {TRANSSPLICED} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=212.8]} {Human: ENSG00000143153, ATP1B1, ATPase Na+/K+ transporting subunit beta 1, [Score=115, Expect=8e-30]} {Mouse: ENSMUSG00000026576, Atp1b1, ATPase, Na+/K+ transporting, beta 1 polypeptide, [Score=117, Expect=2e-30]} {Dmel: FBgn0032946, nrv3, nervana 3, [RH, Score=158, Expect=3e-46]} {Celegans: WBGene00010117, nkb-3, Probable sodium/potassium-transporting ATPase subunit beta-3, [RH, Score=174, Expect=3e-52]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [Score=196, Expect=2e-61]} {RNA1509_1022, RNA1509_10586, RNA1509_48760, RNA1509_56480} {RNA1310_23188.1, RNA1509_1022, RNA1509_10586, RNA1509_48760, RNA1509_56480} {RNA1509_1022, RNA1509_10586, RNA1509_48760, RNA1509_56480, RNA815_9461}
30. MligTC455_44700 2825 58.85 Mlig455_049079

Neo: -

Age: -

Region-enriched R3: 1.667/0.02565

SLC10A1 5.168 0.768 0.837 0.789 0.904 0.908 0.962 Mlig455_049079 {REF} {Length: 2131} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=117.8]; SBF-like CPA transporter family (DUF4137) [PF13593.8, score=36.6]} {Human: ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=124, Expect=4e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=131, Expect=1e-33]} {Dmel: FBgn0030638, CG11655, [Score=154, Expect=2e-41]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=202, Expect=9e-59]} {Smed: dd_Smed_v6_11330_0_1, dd_Smed_v6_11330_0_1, [RH, Score=297, Expect=9e-96]} {RNA1509_41454} {RNA1310_15046, RNA1509_41454} {RNA1509_41454, RNA815_3102}
31. MligTC455_43756 3225 67.19 Mlig455_010402

Neo: -

Age: -

Region-enriched R3: 1.722/0.00762

5.151 0.790 0.836 0.829 0.887 0.853 0.956 Mlig455_010402 {REF} {Length: 2001} {Pfam: Innexin [PF00876.20, score=339.7]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=100, Expect=3e-23]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=291, Expect=2e-95]} {Smed: dd_Smed_v6_734_0_2, dd_Smed_v6_734_0_2, [Score=292, Expect=3e-95]} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1310_16777, RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855, RNA815_7295}
32. MligTC455_17956 4052 84.43 Mlig455_033669, Mlig455_050146

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.218

Region-enriched R3: 1.577/0.00014
Region-enriched R4: 1.297/0.00873
Region-enriched R6: 1.274/0.01524
Region-enriched R5: 1.196/0.00285

AKR1B10 5.147 0.882 0.755 0.777 0.907 0.868 0.958

Mlig455_033669 {REF} {Length: 1299} {TRANSSPLICED} {Pfam: Aldo/keto reductase family [PF00248.23, score=179.4]} {Human: ENSG00000198074, AKR1B10, aldo-keto reductase family 1 member B10, [RH, Score=328, Expect=3e-112]; ENSG00000085662, AKR1B1, aldo-keto reductase family 1 member B, [RH, Score=328, Expect=6e-112]} {Mouse: ENSMUSG00000001642, Akr1b3, aldo-keto reductase family 1, member B3 (aldose reductase), [RH, Score=319, Expect=1e-108]; ENSMUSG00000028692, Akr1a1, aldo-keto reductase family 1, member A1 (aldehyde reductase), [RH, Score=306, Expect=1e-103]; ENSMUSG00000029762, Akr1b8, aldo-keto reductase family 1, member B8, [RH, Score=305, Expect=6e-103]} {Dmel: FBgn0086254, CG6084, [RH, Score=326, Expect=2e-111]} {Celegans: WBGene00012722, Y39G8B.1, [RH, Score=288, Expect=6e-97]} {Smed: dd_Smed_v6_9852_0_1, dd_Smed_v6_9852_0_1, [RH, Score=266, Expect=4e-88]} {RNA1509_6104} {RNA1310_15424} {RNA815_8072}

Mlig455_050146 {REF} {Length: 2314} {Pfam: Aldo/keto reductase family [PF00248.23, score=180.6]} {Human: ENSG00000198074, AKR1B10, aldo-keto reductase family 1 member B10, [RH, Score=329, Expect=2e-112]; ENSG00000085662, AKR1B1, aldo-keto reductase family 1 member B, [RH, Score=328, Expect=4e-112]} {Mouse: ENSMUSG00000001642, Akr1b3, aldo-keto reductase family 1, member B3 (aldose reductase), [RH, Score=319, Expect=1e-108]; ENSMUSG00000028692, Akr1a1, aldo-keto reductase family 1, member A1 (aldehyde reductase), [RH, Score=307, Expect=8e-104]; ENSMUSG00000029762, Akr1b8, aldo-keto reductase family 1, member B8, [RH, Score=305, Expect=3e-103]} {Dmel: FBgn0086254, CG6084, [RH, Score=326, Expect=1e-111]} {Celegans: WBGene00012722, Y39G8B.1, [RH, Score=289, Expect=4e-97]} {Smed: dd_Smed_v6_9852_0_1, dd_Smed_v6_9852_0_1, [RH, Score=266, Expect=3e-88]} {RNA1509_18580, RNA1509_20473, RNA1509_26383, RNA1509_6104} {RNA1310_15424, RNA1509_18580, RNA1509_20473, RNA1509_26383, RNA1509_6104} {RNA1509_18580, RNA1509_20473, RNA1509_26383, RNA1509_6104, RNA815_8072}
33. MligTC455_46181 2902 60.45 Mlig455_054291

Neo: -

Age: logFC(26M/2M)=-0.282

Region-enriched R4: 1.689/0.00164
Region-enriched R3: 1.207/0.03875
Region-enriched R5: 1.162/0.01606

5.142 0.749 0.755 0.888 0.860 0.975 0.915 Mlig455_054291 {REF} {Length: 934} {Pfam: Universal stress protein family [PF00582.28, score=107.5]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=119, Expect=8e-35]} {RNA1509_5080} {RNA1310_45709, RNA1509_5080} {RNA1509_5080, RNA815_23470}
34. MligTC455_15783 5345 111.36 Mlig455_025807, Mlig455_025814

Neo: -

Age: -

Region-enriched R4: 1.633/0.00032
Region-enriched R5: 1.583/0.00001
Region-enriched R6: 1.083/0.03690

GULP1 5.102 0.738 0.741 0.880 0.975 0.917 0.851

Mlig455_025807 {REF} {Length: 1817} {TRANSSPLICED} {Pfam: Phosphotyrosine interaction domain (PTB/PID) [PF00640.25, score=36.5]} {Human: ENSG00000144366, GULP1, GULP, engulfment adaptor PTB domain containing 1, [Score=59.3, Expect=2e-09]} {Mouse: ENSMUSG00000056870, Gulp1, GULP, engulfment adaptor PTB domain containing 1, [Score=56.6, Expect=1e-08]; ENSMUSG00000024219, Anks1, ankyrin repeat and SAM domain containing 1, [Score=53.9, Expect=2e-07]} {Dmel: FBgn0029092, ced-6, [RH, Score=69.7, Expect=1e-12]} {Celegans: WBGene00000420, ced-6, Cell death protein 6, [Score=49.3, Expect=3e-06]} {RNA1509_14211, RNA1509_2504} {RNA1310_16087, RNA1509_14211, RNA1509_2504} {RNA1509_14211, RNA1509_2504, RNA815_6763}

Mlig455_025814 {REF} {Length: 1818} {TRANSSPLICED} {Pfam: Phosphotyrosine interaction domain (PTB/PID) [PF00640.25, score=36.5]} {Human: ENSG00000144366, GULP1, GULP, engulfment adaptor PTB domain containing 1, [Score=59.7, Expect=2e-09]} {Mouse: ENSMUSG00000056870, Gulp1, GULP, engulfment adaptor PTB domain containing 1, [Score=56.6, Expect=1e-08]} {Dmel: FBgn0029092, ced-6, [RH, Score=68.2, Expect=3e-12]} {Celegans: WBGene00000420, ced-6, Cell death protein 6, [Score=47.8, Expect=8e-06]} {RNA1509_2504, RNA1509_44856, RNA1509_48464, RNA1509_9772} {RNA1310_16087, RNA1509_44856, RNA1509_48464, RNA1509_9772} {RNA1509_44856, RNA1509_48464, RNA1509_9772, RNA815_6763}
35. MligTC455_18723 1597 33.27 Mlig455_004384

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.781

Region-enriched R3: 2.164/0.00079
Region-enriched R4: 1.576/0.04930
Region-enriched R5: 1.329/0.03977

SLC3A1 5.1 0.810 0.763 0.768 0.878 0.900 0.981 Mlig455_004384 {REF} {Length: 2040} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=310.6]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=371, Expect=2e-119]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=372, Expect=4e-120]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=384, Expect=2e-126]} {Celegans: WBGene00000224, atgp-1, Amino acid Transporter GlycoProtein subunit, [RH, Score=146, Expect=3e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=8e-12]} {RNA1509_19345} {RNA1310_12682.1} {RNA815_15968}
36. MligTC455_53878 8131 169.39 Mlig455_056351

Neo: -

Age: logFC(26M/2M)=0.398

Region-enriched R3: 1.950/0.00000
Region-enriched R5: 1.089/0.01986

CLCA1 5.092 0.761 0.733 0.916 0.791 0.905 0.986 Mlig455_056351 {REF} {Length: 4429} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=166.8]; von Willebrand factor type A domain [PF00092.30, score=30.4]; von Willebrand factor type A domain [PF13519.8, score=27.0]; von Willebrand factor type A domain [PF13768.8, score=23.5]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=2e-41]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=165, Expect=5e-41]} {Celegans: WBGene00018026, F35A5.4, [Score=58.2, Expect=3e-08]} {RNA1509_656} {RNA1310_5461.1} {RNA815_1665}
37. MligTC455_18724 1612 33.59 Mlig455_037198

Neo: -

Age: -

Region-enriched R3: 2.022/0.00141

SLC3A1 5.091 0.807 0.761 0.768 0.875 0.899 0.981 Mlig455_037198 {REF} {Length: 2052} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=311.9]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=373, Expect=2e-120]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=374, Expect=5e-121]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=385, Expect=1e-126]} {Celegans: WBGene00000225, atgp-2, Amino acid Transporter GlycoProtein subunit, [RH, Score=147, Expect=2e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=9e-12]} {RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1310_12682.1, RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1509_14094, RNA1509_15182, RNA1509_19345, RNA815_15968}
38. MligTC455_46189 3465 72.19 Mlig455_064483

Neo: -

Age: -

Region-enriched R3: 2.108/0.00000
Region-enriched R4: 1.352/0.02878
Region-enriched R5: 1.186/0.01606

ENPEP 5.062 0.777 0.760 0.744 0.897 0.930 0.954 Mlig455_064483 {REF} {Length: 3574} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=253.3]; Peptidase family M1 domain [PF01433.22, score=243.6]; Peptidase M1 N-terminal domain [PF17900.3, score=149.2]} {Human: ENSG00000138792, ENPEP, glutamyl aminopeptidase, [RH, Score=590, Expect=0.0]} {Mouse: ENSMUSG00000028024, Enpep, glutamyl aminopeptidase, [RH, Score=590, Expect=0.0]} {Dmel: FBgn0038135, CG8773, [RH, Score=610, Expect=0.0]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=369, Expect=3e-112]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=479, Expect=2e-153]} {RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985} {RNA1310_3977.1, RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985} {RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985, RNA815_1584}
39. MligTC455_50238 18829 392.26 Mlig455_012786

Neo: -

Age: logFC(26M/2M)=2.865

Region-enriched R3: 1.134/0.04948
Region-enriched R5: 1.029/0.03415

TSPAN7 5.031 0.865 0.739 0.923 0.971 0.739 0.794 Mlig455_012786 {REF} {Length: 1435} {Pfam: Tetraspanin family [PF00335.22, score=141.6]} {Human: ENSG00000156298, TSPAN7, tetraspanin 7, [RH, Score=81.6, Expect=2e-17]} {Mouse: ENSMUSG00000058254, Tspan7, tetraspanin 7, [RH, Score=84.0, Expect=2e-18]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=96.3, Expect=8e-23]} {Celegans: WBGene00006633, tsp-7, Tetraspanin, [Score=67.0, Expect=8e-13]} {Smed: dd_Smed_v6_354_0_1, dd_Smed_v6_354_0_1, [RH, Score=153, Expect=2e-44]} {RNA1509_333} {RNA1310_21956} {RNA815_7133.1}
40. MligTC455_25457 2491 51.89 Mlig455_028995

Neo: -

Age: logFC(26M/2M)=-0.222

Region-enriched R3: 1.404/0.00023

ABCB1 5.026 0.809 0.734 0.885 0.847 0.964 0.787 Mlig455_028995 {REF} {Length: 8120} {Pfam: ABC transporter transmembrane region [PF00664.25, score=423.8]; ABC transporter [PF00005.29, score=235.2]; RecF/RecN/SMC N terminal domain [PF02463.21, score=64.3]; AAA ATPase domain [PF13191.8, score=45.9]; Predicted ATPase of the ABC class [PF09818.11, score=32.2]; P-loop containing region of AAA domain [PF13555.8, score=30.3]; AAA domain [PF13401.8, score=29.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=29.3]; RsgA GTPase [PF03193.18, score=27.5]; AAA domain [PF13238.8, score=24.6]; AAA domain (dynein-related subfamily) [PF07728.16, score=23.8]; Rad17 P-loop domain [PF03215.17, score=22.6]; AAA domain [PF13521.8, score=21.1]; P-loop containing dynein motor region [PF12775.9, score=20.6]; Zeta toxin [PF06414.14, score=20.5]; AAA domain [PF13481.8, score=20.5]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=20.1]; Protein of unknown function (DUF815) [PF05673.15, score=19.9]; AAA domain [PF13604.8, score=19.6]; Cytidylate kinase [PF02224.20, score=18.7]} {Human: ENSG00000085563, ABCB1, ATP binding cassette subfamily B member 1, [Score=1139, Expect=0.0]; ENSG00000005471, ABCB4, ATP binding cassette subfamily B member 4, [Score=1095, Expect=0.0]} {Mouse: ENSMUSG00000040584, Abcb1a, ATP-binding cassette, sub-family B (MDR/TAP), member 1A, [Score=1136, Expect=0.0]; ENSMUSG00000028970, Abcb1b, ATP-binding cassette, sub-family B (MDR/TAP), member 1B, [Score=1123, Expect=0.0]; ENSMUSG00000042476, Abcb4, ATP-binding cassette, sub-family B (MDR/TAP), member 4, [Score=1090, Expect=0.0]} {Dmel: FBgn0010241, Mdr50, Multi drug resistance 50, [RH, Score=865, Expect=0.0]} {Celegans: WBGene00004003, pgp-9, P-GlycoProtein related, [Score=1080, Expect=0.0]} {Smed: dd_Smed_v6_4124_0_1, dd_Smed_v6_4124_0_1, [Score=932, Expect=0.0]} {RNA1509_2606, RNA1509_35960} {RNA1310_1852.1, RNA1509_2606, RNA1509_35960} {RNA1509_2606, RNA1509_35960, RNA815_526.1}
41. MligTC455_42353 5099 106.23 Mlig455_014274, Mlig455_014309, Mlig455_018673

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.786

Region-enriched R3: 2.226/0.00003

AC113554.1, ACE 5.025 0.807 0.795 0.806 0.858 0.805 0.954

Mlig455_014274 {REF} {Length: 2949} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_37062, RNA1509_441} {RNA1310_8949, RNA1509_37062} {RNA1509_37062, RNA815_4061}

Mlig455_014309 {REF} {Length: 2926} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441} {RNA1310_8949} {RNA815_4061}

Mlig455_018673 {REF} {Length: 833} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=122.4]} {Human: ENSG00000264813, AC113554.1, novel transcript, [Score=103, Expect=3e-24]; ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=103, Expect=2e-24]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=97.8, Expect=2e-22]; ENSMUSG00000101605, Ace3, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, [Score=93.2, Expect=6e-21]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [Score=74.7, Expect=7e-15]} {Smed: dd_Smed_v6_13804_0_1, dd_Smed_v6_13804_0_1, [Score=51.2, Expect=2e-07]} {RNA1509_16360} {RNA1310_8949} {RNA815_4061}
42. MligTC455_27409 4850 101.04 Mlig455_040849

Neo: -

Age: -

Region-enriched R3: 1.209/0.03173
Region-enriched R5: 1.057/0.02461

CLTC 5.012 0.795 0.824 0.818 0.820 0.950 0.805 Mlig455_040849 {REF} {Length: 5909} {Pfam: Region in Clathrin and VPS [PF00637.22, score=644.4]; Clathrin propeller repeat [PF01394.22, score=127.7]; Clathrin-H-link [PF13838.8, score=115.4]; Clathrin, heavy-chain linker [PF09268.12, score=39.2]; Coatomer WD associated region [PF04053.16, score=32.1]; Tetratricopeptide repeat [PF13428.8, score=20.6]} {Human: ENSG00000141367, CLTC, clathrin heavy chain, [RH, Score=2641, Expect=0.0]} {Mouse: ENSMUSG00000047126, Cltc, clathrin, heavy polypeptide (Hc), [RH, Score=2639, Expect=0.0]} {Dmel: FBgn0000319, Chc, Clathrin heavy chain, [RH, Score=2532, Expect=0.0]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [RH, Score=2347, Expect=0.0]} {Smed: dd_Smed_v6_59_0_1, dd_Smed_v6_59_0_1, [RH, Score=2676, Expect=0.0]} {RNA1509_21498, RNA1509_4619, RNA1509_592, RNA1509_6857, RNA1509_7483} {RNA1310_523.1, RNA1509_21498, RNA1509_4619, RNA1509_6857, RNA1509_7483} {RNA1509_21498, RNA1509_4619, RNA1509_6857, RNA1509_7483, RNA815_198.1}
43. MligTC455_50239 18215 379.48 Mlig455_047408

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.193

Region-enriched R3: 1.205/0.01671
Region-enriched R5: 1.176/0.00614
Region-enriched R6: 1.135/0.04579

TSPAN7 4.972 0.828 0.746 0.872 0.950 0.777 0.799 Mlig455_047408 {REF} {Length: 1648} {Pfam: Tetraspanin family [PF00335.22, score=140.8]} {Human: ENSG00000156298, TSPAN7, tetraspanin 7, [RH, Score=80.9, Expect=8e-17]} {Mouse: ENSMUSG00000058254, Tspan7, tetraspanin 7, [RH, Score=83.2, Expect=9e-18]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=95.5, Expect=3e-22]} {Celegans: WBGene00006633, tsp-7, Tetraspanin, [Score=66.6, Expect=2e-12]} {Smed: dd_Smed_v6_354_0_1, dd_Smed_v6_354_0_1, [RH, Score=153, Expect=2e-43]} {RNA1509_2526, RNA1509_333, RNA1509_55166, RNA1509_55530} {RNA1310_21956, RNA1509_2526, RNA1509_55166, RNA1509_55530} {RNA1509_2526, RNA1509_55166, RNA1509_55530, RNA815_7133.1}
44. MligTC455_19521 1093 22.77 Mlig455_056856

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.248

Region-enriched R4: 1.796/0.00007

4.865 0.793 0.787 0.701 0.966 0.786 0.832 Mlig455_056856 {REF} {Length: 2007} {Pfam: Phosphatidyl serine synthase [PF03034.17, score=22.0]} {Mouse: ENSMUSG00000025495, Ptdss2, phosphatidylserine synthase 2, [Score=55.8, Expect=3e-10]} {Smed: dd_Smed_v6_7678_0_1, dd_Smed_v6_7678_0_1, [Score=84.3, Expect=1e-20]} {RNA1509_25799} {RNA1310_5581} {RNA815_3642.1}
45. MligTC455_44102 5169 107.69 Mlig455_011991

Neo: -

Age: logFC(26M/2M)=0.278

Region-enriched R3: 1.948/0.00360
Region-enriched R4: 1.688/0.02863

HPGDS 4.528 0.904 - 0.870 0.951 0.858 0.945 Mlig455_011991 {REF} {Length: 1746} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=43.5]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=42.8]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=22.6]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=20.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=19.1]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [Score=67.8, Expect=2e-13]} {Mouse: ENSMUSG00000025934, Gsta3, glutathione S-transferase, alpha 3, [Score=62.4, Expect=1e-11]; ENSMUSG00000032348, Gsta4, glutathione S-transferase, alpha 4, [Score=60.5, Expect=6e-11]; ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [Score=60.5, Expect=5e-11]} {Celegans: WBGene00001756, gst-8, Probable glutathione S-transferase 8, [Score=84.0, Expect=5e-20]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=115, Expect=4e-32]} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1310_14959.1, RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359, RNA815_7403}
46. MligTC455_35217 5138 107.05 Mlig455_014282, Mlig455_014335

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.399

Region-enriched R3: 1.348/0.01129

4.513 0.938 0.901 - 0.848 0.876 0.950

Mlig455_014282 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=158.0]} {RNA1509_22501, RNA1509_4768} {RNA1310_7742.1, RNA1509_22501} {RNA1509_22501, RNA815_6411}

Mlig455_014335 {REF} {Length: 1769} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=159.5]} {RNA1509_4768} {RNA1310_7742.1} {RNA815_6411}
47. MligTC455_40312 3856 80.34 Mlig455_008661, Mlig455_008672

Neo: -

Age: Down-Up-Up

Region-enriched R3: 2.080/0.00320

CYP2J2 4.49 0.900 0.739 - 0.913 0.980 0.958

Mlig455_008661 {REF} {Length: 2369} {Pfam: Cytochrome P450 [PF00067.24, score=340.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=298, Expect=3e-95]} {Mouse: ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=2e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=276, Expect=1e-86]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=3e-86]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=274, Expect=6e-86]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=4e-85]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=2e-84]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=270, Expect=2e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=269, Expect=6e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=2e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=5e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=219, Expect=9e-65]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=262, Expect=1e-81]} {RNA1509_32472, RNA1509_3430} {RNA1310_10280, RNA1509_32472, RNA1509_3430} {RNA1509_32472, RNA1509_3430, RNA815_4805}

Mlig455_008672 {REF} {Length: 2348} {Pfam: Cytochrome P450 [PF00067.24, score=341.0]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=298, Expect=3e-95]} {Mouse: ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=2e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=276, Expect=1e-86]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=2e-86]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=274, Expect=5e-86]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=4e-85]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=2e-84]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=269, Expect=6e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=269, Expect=7e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=3e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=6e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=219, Expect=7e-65]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=248, Expect=3e-76]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=261, Expect=3e-81]} {RNA1509_32472} {RNA1310_10280} {RNA815_4805}
48. MligTC455_45291 2427 50.57 Mlig455_024270

Neo: -

Age: -

Region-enriched R3: 1.846/0.00333

SUSD2 4.473 0.832 - 0.888 0.970 0.955 0.828 Mlig455_024270 {REF} {Length: 4363} {Pfam: AMOP domain [PF03782.19, score=54.3]; von Willebrand factor type D domain [PF00094.27, score=35.6]; Nidogen-like [PF06119.16, score=28.7]} {Human: ENSG00000099994, SUSD2, sushi domain containing 2, [Score=120, Expect=4e-27]} {Mouse: ENSMUSG00000006342, Susd2, sushi domain containing 2, [RH, Score=134, Expect=1e-31]} {Dmel: FBgn0051004, mesh, [RH, Score=159, Expect=4e-39]} {RNA1509_10841, RNA1509_1220, RNA1509_24159, RNA1509_25642, RNA1509_33791, RNA1509_46716} {RNA1310_2718.1, RNA1509_10841, RNA1509_1220, RNA1509_24159, RNA1509_25642, RNA1509_33791, RNA1509_46716} {RNA1509_10841, RNA1509_1220, RNA1509_24159, RNA1509_25642, RNA1509_33791, RNA1509_46716, RNA815_500}
49. MligTC455_44136 8031 167.32 Mlig455_024689, Mlig455_024714

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.859

Region-enriched R4: 1.310/0.01340
Region-enriched R3: 1.215/0.02536

FADS2 4.47 - 0.783 0.816 0.990 0.922 0.959

Mlig455_024689 {REF} {Length: 3861} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=116.9]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=429, Expect=6e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=426, Expect=8e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=446, Expect=7e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=3e-109]} {RNA1509_1792, RNA1509_9754} {RNA1310_4526, RNA1509_1792, RNA1509_9754} {RNA1509_1792, RNA1509_9754, RNA815_4497}

Mlig455_024714 {REF} {Length: 5232} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=117.3]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=430, Expect=3e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=427, Expect=2e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=447, Expect=3e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=6e-109]} {RNA1509_9754} {RNA1310_4526} {RNA815_4497}
50. MligTC455_45290 2414 50.29 Mlig455_024268

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=8.245

Region-enriched R3: 1.852/0.00444

4.467 0.832 - 0.888 0.971 0.955 0.821 Mlig455_024268 {REF} {Length: 1621} {RNA1509_33791} {RNA1310_2718.1} {RNA815_500}
51. MligTC455_49659 4741 98.77 Mlig455_011512, Mlig455_050003

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.314

Region-enriched R3: 1.923/0.00380

4.443 0.887 0.813 - 0.907 0.849 0.987

Mlig455_011512 {REF} {Length: 2299} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}

Mlig455_050003 {REF} {Length: 1812} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}
52. MligTC455_27869 8765 182.6 Mlig455_051857, Mlig455_051868, Mlig455_051893

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.214/0.00040
Region-enriched R5: 1.603/0.01133

ANPEP 4.433 0.810 0.772 0.926 0.960 0.965 -

Mlig455_051857 {REF} {Length: 3680} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=238.0]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=560, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=546, Expect=6e-179]} {Dmel: FBgn0039640, CG14516, [RH, Score=536, Expect=1e-174]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=599, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051868 {REF} {Length: 4344} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=259.5]; Peptidase family M1 domain [PF01433.22, score=234.1]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=552, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [Score=542, Expect=4e-177]} {Dmel: FBgn0039640, CG14516, [RH, Score=529, Expect=7e-172]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=406, Expect=1e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=595, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051893 {REF} {Length: 4373} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=236.2]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=558, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=545, Expect=3e-178]} {Dmel: FBgn0039640, CG14516, [RH, Score=533, Expect=2e-173]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=596, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}
53. MligTC455_42042 5653 117.77 Mlig455_011072

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.324

Region-enriched R3: 1.823/0.00256

4.402 0.885 0.812 0.884 0.974 - 0.847 Mlig455_011072 {REF} {Length: 901} {Pfam: Lipocalin / cytosolic fatty-acid binding protein family [PF00061.25, score=22.3]; PRELI-like family [PF04707.16, score=19.8]} {RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378} {RNA1310_48326.1, RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378} {RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378, RNA815_23354}
54. MligTC455_24083 6997 145.77 Mlig455_007319

Neo: -

Age: -

Region-enriched R3: 2.037/0.00010
Region-enriched R5: 1.165/0.04106

ACHE 4.371 0.811 0.745 0.920 - 0.921 0.974 Mlig455_007319 {REF} {Length: 2399} {Pfam: Carboxylesterase family [PF00135.30, score=344.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=233, Expect=9e-68]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=225, Expect=3e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=183, Expect=6e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=228, Expect=1e-66]} {Smed: dd_Smed_v6_4800_0_1, dd_Smed_v6_4800_0_1, [Score=184, Expect=4e-50]} {RNA1509_195, RNA1509_4270, RNA1509_51012} {RNA1310_9229, RNA1509_4270, RNA1509_51012} {RNA1509_4270, RNA1509_51012, RNA815_3141.1}
55. MligTC455_51880 13248 275.99 Mlig455_059444

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-3.002

Region-enriched R3: 1.727/0.04203

4.369 0.958 0.867 0.900 0.863 0.781 - Mlig455_059444 {REF} {Length: 1115} {RNA1509_16825, RNA1509_20241, RNA1509_31277, RNA1509_40483, RNA1509_410, RNA1509_7504} {RNA1310_33614.1, RNA1509_16825, RNA1509_20241, RNA1509_31277, RNA1509_40483, RNA1509_410, RNA1509_7504} {RNA1509_16825, RNA1509_20241, RNA1509_31277, RNA1509_40483, RNA1509_410, RNA1509_7504, RNA815_18624}
56. MligTC455_18980 2453 51.11 Mlig455_051123

Neo: -

Age: logFC(26M/2M)=-0.250

TSPAN6 4.368 - 0.806 0.951 0.899 0.788 0.924 Mlig455_051123 {REF} {Length: 2220} {Pfam: Tetraspanin family [PF00335.22, score=103.8]} {Human: ENSG00000000003, TSPAN6, tetraspanin 6, [Score=67.8, Expect=1e-12]} {Mouse: ENSMUSG00000028699, Tspan1, tetraspanin 1, [Score=69.3, Expect=2e-13]} {Dmel: FBgn0027865, Tsp96F, Tetraspanin 96F, [Score=60.5, Expect=3e-10]} {Celegans: WBGene00006643, tsp-17, TetraSPanin family, [Score=70.1, Expect=9e-14]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [Score=93.6, Expect=3e-22]} {RNA1509_30747, RNA1509_8575, RNA1509_9121} {RNA1310_961, RNA1509_30747, RNA1509_8575, RNA1509_9121} {RNA1509_30747, RNA1509_8575, RNA1509_9121, RNA815_10076}
57. MligTC455_53879 3408 71 Mlig455_056363

Neo: -

Age: logFC(26M/2M)=0.278

Region-enriched R3: 1.852/0.00001

CLCA1 4.332 0.796 0.782 0.835 - 0.941 0.978 Mlig455_056363 {REF} {Length: 3111} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=167.5]; von Willebrand factor type A domain [PF00092.30, score=46.2]; von Willebrand factor type A domain [PF13519.8, score=42.1]; von Willebrand factor type A domain [PF13768.8, score=37.2]; VWA domain containing CoxE-like protein [PF05762.16, score=23.6]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [RH, Score=265, Expect=9e-75]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [RH, Score=273, Expect=6e-78]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [RH, Score=178, Expect=5e-46]} {RNA1509_656} {RNA1310_5461.1} {RNA815_1665}
58. MligTC455_44455 1551 32.32 Mlig455_047856

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.469/0.00004
Region-enriched R6: 1.024/0.03210

THAP4 4.321 0.889 - 0.714 0.929 0.951 0.838 Mlig455_047856 {REF} {Length: 2506} {Pfam: THAP domain [PF05485.14, score=87.0]} {Human: ENSG00000176946, THAP4, THAP domain containing 4, [RH, Score=63.5, Expect=9e-11]} {Mouse: ENSMUSG00000026279, Thap4, THAP domain containing 4, [RH, Score=64.7, Expect=3e-11]} {Smed: dd_Smed_v6_3208_0_1, dd_Smed_v6_3208_0_1, [Score=75.9, Expect=4e-16]} {RNA1509_8361} {RNA1310_19209.3} {RNA815_34212}
59. MligTC455_38390 5253 109.43 Mlig455_012923

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.677

Region-enriched R3: 1.882/0.01066

KREMEN1 4.312 0.872 0.765 0.827 0.967 - 0.881 Mlig455_012923 {REF} {Length: 983} {Pfam: WSC domain [PF01822.21, score=64.1]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=55.8, Expect=1e-09]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=53.5, Expect=6e-09]} {Dmel: FBgn0046685, Wsck, [Score=57.8, Expect=1e-10]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=44.7, Expect=4e-06]} {RNA1509_11244} {RNA1310_67645} {RNA815_21733.1}
60. MligTC455_35632 6861 142.93 Mlig455_047206

Neo: -

Age: -

Region-enriched R3: 1.984/0.00032
Region-enriched R4: 1.605/0.01274
Region-enriched R5: 1.441/0.00908

DHDH 4.31 - 0.858 0.860 0.724 0.965 0.903 Mlig455_047206 {REF} {Length: 1483} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=86.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=245, Expect=8e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=247, Expect=1e-79]} {Dmel: FBgn0031418, CG3609, [Score=229, Expect=5e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=211, Expect=2e-66]} {RNA1509_4889} {RNA1310_24236} {RNA815_11111.1}
61. MligTC455_24858 1486 30.96 Mlig455_010034

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.400/0.00000
Region-enriched R6: 1.421/0.04359
Region-enriched R5: 1.196/0.02139

4.306 0.872 0.773 0.808 0.960 - 0.893 Mlig455_010034 {REF} {Length: 2774} {Pfam: Multi-glycosylated core protein 24 (MGC-24), sialomucin [PF05283.13, score=48.3]} {Mouse: ENSMUSG00000050912, Tmem123, transmembrane protein 123, [Score=44.3, Expect=1e-05]} {Dmel: FBgn0045823, vsg, visgun, [RH, Score=53.1, Expect=8e-09]} {Smed: dd_Smed_v6_828_0_1, dd_Smed_v6_828_0_1, [RH, Score=50.8, Expect=1e-09]} {RNA1509_3563, RNA1509_4599, RNA1509_7753} {RNA1310_22791, RNA1509_3563, RNA1509_4599, RNA1509_7753} {RNA1509_3563, RNA1509_4599, RNA1509_7753, RNA815_10514.1}
62. MligTC455_42467 4040 84.17 Mlig455_037678

Neo: -

Age: -

Region-enriched R6: 1.657/0.00557

4.295 0.951 0.835 - 0.953 0.842 0.714 Mlig455_037678 {REF} {Length: 1518} {RNA1509_2050} {RNA1310_31076.1, RNA1509_2050} {RNA1509_2050, RNA815_6170.2}
63. MligTC455_18868 1328 27.67 Mlig455_067483

Neo: -

Age: -

Region-enriched R3: 1.928/0.00492
Region-enriched R4: 1.837/0.01691
Region-enriched R5: 1.462/0.02245

4.293 0.766 - 0.897 0.843 0.837 0.950 Mlig455_067483 {REF} {Length: 405} {RNA1509_5037} {RNA1310_19379} {RNA815_6182.1}
64. MligTC455_38362 1015 21.16 Mlig455_045508

Neo: -

Age: -

Region-enriched R4: 1.693/0.01745
Region-enriched R5: 1.163/0.02906

AADAC 4.284 0.830 - 0.764 0.873 0.853 0.964 Mlig455_045508 {REF} {Length: 2224} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=113.1]; Carboxylesterase family [PF00135.30, score=19.9]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=96.3, Expect=2e-21]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=102, Expect=1e-23]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=98.2, Expect=3e-22]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=65.5, Expect=4e-11]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=98.2, Expect=2e-22]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=82.0, Expect=5e-17]} {RNA1509_14307} {RNA1310_15560.2} {RNA815_8354}
65. MligTC455_24112 7326 152.63 Mlig455_006637, Mlig455_070643

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

CYP2D6, CYP2U1 4.283 0.746 - 0.848 0.847 0.877 0.965

Mlig455_006637 {REF} {Length: 1777} {Pfam: Cytochrome P450 [PF00067.24, score=343.6]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=263, Expect=7e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=263, Expect=2e-81]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=260, Expect=2e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=259, Expect=4e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=2e-79]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=1e-79]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=3e-79]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=257, Expect=4e-79]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=285, Expect=3e-90]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=283, Expect=1e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=278, Expect=2e-87]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=273, Expect=2e-85]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=271, Expect=8e-85]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=271, Expect=1e-84]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=207, Expect=1e-60]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=292, Expect=3e-93]} {RNA1509_10420} {RNA1310_15091.1} {RNA815_4606.2}

Mlig455_070643 {REF} {Length: 2371} {Pfam: Cytochrome P450 [PF00067.24, score=337.1]} {Human: ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=261, Expect=1e-80]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=260, Expect=7e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=259, Expect=3e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=254, Expect=3e-78]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=280, Expect=2e-88]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=279, Expect=7e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=275, Expect=3e-86]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=268, Expect=1e-83]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=268, Expect=1e-83]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=266, Expect=7e-83]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=201, Expect=4e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=288, Expect=2e-91]} {RNA1509_10420, RNA1509_36519} {RNA1310_15091.1, RNA1509_10420, RNA1509_36519} {RNA1509_10420, RNA1509_36519, RNA815_4606.2}
66. MligTC455_52971 2407 50.15 Mlig455_050623

Neo: -

Age: logFC(26M/2M)=-0.616

Region-enriched R4: 1.402/0.00014
Region-enriched R3: 1.372/0.00001

4.277 0.871 0.729 0.790 - 0.957 0.930 Mlig455_050623 {REF} {Length: 1302} {RNA1509_18850, RNA1509_3980, RNA1509_4657} {RNA1310_29014, RNA1509_18850, RNA1509_3980, RNA1509_4657} {RNA1509_18850, RNA1509_3980, RNA1509_4657, RNA815_8071.2}
67. MligTC455_18869 1346 28.04 Mlig455_067491

Neo: -

Age: -

Region-enriched R3: 1.933/0.00397
Region-enriched R4: 1.775/0.01938
Region-enriched R5: 1.440/0.02287

4.277 0.763 - 0.900 0.842 0.820 0.952 Mlig455_067491 {REF} {Length: 2320} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=72.5]; GDP-mannose 4,6 dehydratase [PF16363.7, score=51.3]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=46.4]; Male sterility protein [PF07993.14, score=42.2]; NAD(P)H-binding [PF13460.8, score=39.3]; Polysaccharide biosynthesis protein [PF02719.17, score=30.0]; KR domain [PF08659.12, score=29.5]; NmrA-like family [PF05368.15, score=28.0]; short chain dehydrogenase [PF00106.27, score=19.3]} {Celegans: WBGene00017429, F13D11.4, [RH, Score=213, Expect=4e-66]} {RNA1509_20033, RNA1509_5037} {RNA1310_19379, RNA1509_20033, RNA1509_5037} {RNA1509_20033, RNA1509_5037, RNA815_6182.1}
68. MligTC455_42649 1111 23.15 Mlig455_033920

Neo: -

Age: logFC(26M/2M)=0.288

TPTE2 4.195 0.738 - 0.720 0.958 0.846 0.933 Mlig455_033920 {REF} {Length: 2398} {Pfam: C2 domain of PTEN tumour-suppressor protein [PF10409.11, score=66.0]; Ion transport protein [PF00520.33, score=35.9]; Dual specificity phosphatase, catalytic domain [PF00782.22, score=28.9]; Protein-tyrosine phosphatase [PF00102.29, score=24.5]; Inositol hexakisphosphate [PF14566.8, score=22.0]} {Human: ENSG00000132958, TPTE2, transmembrane phosphoinositide 3-phosphatase and tensin homolog 2, [RH, Score=373, Expect=6e-124]} {Mouse: ENSMUSG00000031481, Tpte, transmembrane phosphatase with tensin homology, [RH, Score=384, Expect=1e-126]} {Dmel: FBgn0026379, Pten, Phosphatase and tensin homolog, [Score=171, Expect=9e-48]} {Celegans: WBGene00000913, daf-18, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18, [Score=137, Expect=5e-34]} {Smed: dd_Smed_v6_4925_0_2, dd_Smed_v6_4925_0_2, [RH, Score=424, Expect=7e-145]} {RNA1509_26060, RNA1509_6952} {RNA1310_16625.1, RNA1509_26060, RNA1509_6952} {RNA1509_26060, RNA1509_6952, RNA815_5966}
69. MligTC455_27540 1669 34.76 Mlig455_050550

Neo: -

Age: logFC(26M/2M)=0.741

Region-enriched R3: 2.399/0.00000
Region-enriched R4: 1.902/0.00065
Region-enriched R5: 1.309/0.00668

4.186 0.702 - 0.848 0.768 0.950 0.918 Mlig455_050550 {REF} {Length: 2834} {RNA1509_43749, RNA1509_45402} {RNA1310_6417, RNA1509_45402} {RNA1509_45402, RNA815_8474.1}
70. MligTC455_36347 2542 52.97 Mlig455_027675

Neo: -

Age: -

ACP7 4.095 0.745 - 0.776 0.721 0.883 0.970 Mlig455_027675 {REF} {Length: 2194} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=89.6]; Iron/zinc purple acid phosphatase-like protein C [PF14008.8, score=79.5]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=75.2]; PhoD-like phosphatase [PF09423.12, score=19.2]} {Human: ENSG00000183760, ACP7, acid phosphatase 7, tartrate resistant (putative), [RH, Score=431, Expect=2e-148]} {Mouse: ENSMUSG00000037469, Acp7, acid phosphatase 7, tartrate resistant, [RH, Score=448, Expect=1e-154]} {Dmel: FBgn0030245, CG1637, [RH, Score=434, Expect=9e-150]} {Celegans: WBGene00219316, F21A3.11, Purple acid phosphatase, [RH, Score=406, Expect=2e-138]} {Smed: dd_Smed_v6_1053_0_1, dd_Smed_v6_1053_0_1, [RH, Score=537, Expect=0.0]} {RNA1509_2158} {RNA1310_12511.1, RNA1509_2158} {RNA1509_2158, RNA815_6230.1}
71. MligTC455_22491 3631 75.65 Mlig455_041782

Neo: -

Age: logFC(26M/2M)=0.178

ACADM 4.089 0.754 0.744 - 0.747 0.950 0.894 Mlig455_041782 {REF} {Length: 2312} {TRANSSPLICED} {Pfam: Acyl-CoA dehydrogenase, C-terminal domain [PF00441.26, score=164.4]; Acyl-CoA dehydrogenase, middle domain [PF02770.21, score=98.2]; Acyl-CoA dehydrogenase, N-terminal domain [PF02771.18, score=87.8]; Acyl-CoA dehydrogenase, C-terminal domain [PF08028.13, score=74.7]} {Human: ENSG00000117054, ACADM, acyl-CoA dehydrogenase medium chain, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000062908, Acadm, acyl-Coenzyme A dehydrogenase, medium chain, [RH, Score=538, Expect=0.0]} {Dmel: FBgn0035811, CG12262, [RH, Score=577, Expect=0.0]} {Celegans: WBGene00020812, acdh-7, Acyl CoA DeHydrogenase, [RH, Score=495, Expect=5e-175]} {Smed: dd_Smed_v6_5980_0_1, dd_Smed_v6_5980_0_1, [Score=268, Expect=2e-86]} {RNA1509_2791, RNA1509_39085, RNA1509_51931, RNA1509_55101, RNA1509_6225} {RNA1310_12664.1, RNA1509_39085, RNA1509_51931, RNA1509_55101, RNA1509_6225} {RNA1509_39085, RNA1509_51931, RNA1509_55101, RNA1509_6225, RNA815_4550}
72. MligTC455_41866 2789 58.1 Mlig455_053658, Mlig455_053662

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.383

Region-enriched R3: 2.037/0.00117

AC113554.1, ACE 4.082 0.746 0.713 0.749 - 0.971 0.903

Mlig455_053658 {REF} {Length: 2590} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=652.1]} {Human: ENSG00000264813, AC113554.1, novel transcript, [Score=461, Expect=2e-153]; ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=461, Expect=2e-153]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=459, Expect=1e-146]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [RH, Score=441, Expect=2e-147]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [RH, Score=212, Expect=1e-58]} {Smed: dd_Smed_v6_6160_0_1, dd_Smed_v6_6160_0_1, [Score=358, Expect=2e-115]} {RNA1509_21944} {RNA1310_8120.1} {RNA815_2871.1}

Mlig455_053662 {REF} {Length: 2655} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=648.5]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=462, Expect=3e-148]; ENSG00000264813, AC113554.1, novel transcript, [Score=461, Expect=4e-153]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=457, Expect=3e-146]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [RH, Score=437, Expect=1e-145]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [RH, Score=209, Expect=9e-58]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=361, Expect=2e-116]} {RNA1509_21944, RNA1509_37454, RNA1509_37991} {RNA1310_8120.1, RNA1509_37454, RNA1509_37991} {RNA1509_37454, RNA1509_37991, RNA815_2871.1}
73. MligTC455_36732 603 12.57 Mlig455_047172

Neo: -

Age: -

Region-enriched R4: 2.135/0.00012
Region-enriched R3: 1.740/0.00166
Region-enriched R5: 1.657/0.00064

RAC2 4.07 0.736 - 0.744 0.956 0.752 0.882 Mlig455_047172 {REF} {Length: 1561} {Pfam: Ras family [PF00071.24, score=184.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=79.1]; ADP-ribosylation factor family [PF00025.23, score=31.9]} {Human: ENSG00000128340, RAC2, Rac family small GTPase 2, [RH, Score=344, Expect=2e-122]; ENSG00000169750, RAC3, Rac family small GTPase 3, [RH, Score=328, Expect=5e-116]} {Mouse: ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [RH, Score=342, Expect=2e-121]; ENSMUSG00000018012, Rac3, Rac family small GTPase 3, [RH, Score=328, Expect=3e-116]} {Dmel: FBgn0010333, Rac1, [RH, Score=340, Expect=5e-121]} {Celegans: WBGene00000424, ced-10, Ras-related protein ced-10, [Score=320, Expect=4e-113]} {Smed: dd_Smed_v6_610_0_1, dd_Smed_v6_610_0_1, [RH, Score=315, Expect=2e-111]} {RNA1509_40868} {RNA1310_28906.1} {RNA815_13153}
74. MligTC455_17728 1061 22.09 Mlig455_057691

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-4.029

Region-enriched R6: 1.981/0.02890

4.06 0.789 0.705 0.767 0.957 - 0.842 Mlig455_057691 {REF} {Length: 717} {RNA1509_20501} {RNA1310_48596} {RNA815_26649}
75. MligTC455_17863 8586 178.87 Mlig455_011849, Mlig455_013127

Neo: -

Age: -

PROM1 4.011 - 0.764 0.722 0.954 0.754 0.817

Mlig455_011849 {REF} {Length: 3355} {TRANSSPLICED} {Pfam: Prominin [PF05478.13, score=193.7]} {Human: ENSG00000007062, PROM1, prominin 1, [Score=81.3, Expect=5e-15]} {Mouse: ENSMUSG00000029086, Prom1, prominin 1, [Score=130, Expect=1e-30]} {Smed: dd_Smed_v6_4461_0_1, dd_Smed_v6_4461_0_1, [Score=162, Expect=4e-41]} {RNA1509_11514, RNA1509_15085, RNA1509_21096, RNA1509_43496} {RNA1310_4103.1, RNA1509_11514, RNA1509_15085, RNA1509_21096} {RNA1509_11514, RNA1509_15085, RNA1509_21096, RNA815_1781}

Mlig455_013127 {REF} {Length: 3361} {TRANSSPLICED} {Pfam: Prominin [PF05478.13, score=193.7]} {Human: ENSG00000007062, PROM1, prominin 1, [Score=81.3, Expect=5e-15]} {Mouse: ENSMUSG00000029086, Prom1, prominin 1, [Score=130, Expect=1e-30]} {Smed: dd_Smed_v6_4461_0_1, dd_Smed_v6_4461_0_1, [Score=162, Expect=4e-41]} {RNA1509_43496} {RNA1310_4103.1, RNA1509_43496} {RNA1509_43496, RNA815_1781}
76. MligTC455_45337 3435 71.56 Mlig455_022362

Neo: -

Age: logFC(26M/2M)=-0.291

TXNRD1 3.943 0.762 0.757 - 0.951 0.707 0.766 Mlig455_022362 {REF} {Length: 2783} {TRANSSPLICED} {Pfam: Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=203.8]; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [PF02852.24, score=78.9]; Glutaredoxin [PF00462.26, score=69.1]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=64.8]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=44.5]; Alanine dehydrogenase/PNT, C-terminal domain [PF01262.23, score=26.5]; FAD binding domain [PF00890.26, score=26.4]; Glucose inhibited division protein A [PF01134.24, score=20.9]; FAD dependent oxidoreductase [PF12831.9, score=20.8]; Thi4 family [PF01946.19, score=19.8]} {Human: ENSG00000198431, TXNRD1, thioredoxin reductase 1, [RH, Score=577, Expect=0.0]; ENSG00000197763, TXNRD3, thioredoxin reductase 3, [RH, Score=571, Expect=0.0]} {Mouse: ENSMUSG00000000811, Txnrd3, thioredoxin reductase 3, [RH, Score=563, Expect=0.0]} {Dmel: FBgn0020653, Trxr-1, Thioredoxin reductase-1, [RH, Score=484, Expect=1e-166]} {Celegans: WBGene00015553, trxr-1, Thioredoxin reductase 1, [RH, Score=486, Expect=5e-165]} {Smed: dd_Smed_v6_960_0_1, dd_Smed_v6_960_0_1, [RH, Score=590, Expect=0.0]} {RNA1509_1268, RNA1509_4098, RNA1509_7641} {RNA1310_6460.1, RNA1509_1268, RNA1509_4098, RNA1509_7641} {RNA1509_1268, RNA1509_4098, RNA1509_7641, RNA815_2233}
77. MligTC455_41983 2249 46.86 Mlig455_014572

Neo: -

Age: -

Region-enriched R4: 2.314/0.00000
Region-enriched R3: 1.500/0.00235
Region-enriched R6: 1.362/0.01872
Region-enriched R5: 1.347/0.00318

BHMT 3.643 0.913 - - 0.888 0.884 0.958 Mlig455_014572 {REF} {Length: 2550} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=161.0]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=542, Expect=0.0]} {Mouse: ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=545, Expect=0.0]; ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=545, Expect=0.0]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=555, Expect=0.0]} {RNA1509_18954, RNA1509_57529} {RNA1310_18981.1, RNA1509_18954} {RNA1509_18954, RNA815_5900.2}
78. MligTC455_41617 3461 72.1 Mlig455_042207, Mlig455_059028

Neo: -

Age: logFC(26M/2M)=0.240

CH25H 3.615 0.856 - - 0.961 0.848 0.950

Mlig455_042207 {REF} {Length: 1383} {Pfam: Fatty acid hydroxylase superfamily [PF04116.15, score=73.2]} {Human: ENSG00000138135, CH25H, cholesterol 25-hydroxylase, [RH, Score=170, Expect=8e-51]} {Mouse: ENSMUSG00000050370, Ch25h, cholesterol 25-hydroxylase, [RH, Score=182, Expect=3e-55]} {Celegans: WBGene00018036, F35C8.5, Cholesterol 25-hydroxylase-like protein, [Score=187, Expect=3e-57]} {RNA1509_2368} {RNA1310_977} {RNA815_9011}

Mlig455_059028 {REF} {Length: 1358} {Pfam: Fatty acid hydroxylase superfamily [PF04116.15, score=73.2]} {Human: ENSG00000138135, CH25H, cholesterol 25-hydroxylase, [RH, Score=170, Expect=8e-51]} {Mouse: ENSMUSG00000050370, Ch25h, cholesterol 25-hydroxylase, [RH, Score=182, Expect=3e-55]} {Celegans: WBGene00018036, F35C8.5, Cholesterol 25-hydroxylase-like protein, [Score=187, Expect=3e-57]} {RNA1509_2368} {RNA1310_977} {RNA815_9011}
79. MligTC455_50268 10100 210.41 Mlig455_024148

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-1.068

Region-enriched R6: 1.945/0.02177
Region-enriched R4: 1.750/0.03408
Region-enriched R5: 1.568/0.02282

3.573 0.803 - 0.867 0.920 0.983 - Mlig455_024148 {REF} {Length: 921} {RNA1509_6091} {RNA1310_41540, RNA1509_6091} {RNA1509_6091, RNA815_20414.1}
80. MligTC455_15678 9353 194.86 Mlig455_044843

Neo: -

Age: -

Region-enriched R3: 2.225/0.00001

MOXD1 3.556 0.768 - 0.888 0.962 0.938 - Mlig455_044843 {REF} {Length: 2852} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=86.4]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=60.8]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=111, Expect=4e-25]; ENSG00000123454, DBH, dopamine beta-hydroxylase, [Score=107, Expect=1e-23]} {Mouse: ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=115, Expect=2e-26]; ENSMUSG00000000889, Dbh, dopamine beta hydroxylase, [Score=112, Expect=1e-25]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=122, Expect=7e-29]} {Celegans: WBGene00006541, tbh-1, Tyramine beta-hydroxylase, [Score=105, Expect=1e-23]} {Smed: dd_Smed_v6_42610_0_1, dd_Smed_v6_42610_0_1, [Score=116, Expect=3e-28]} {RNA1509_19571, RNA1509_21722, RNA1509_28470, RNA1509_33241, RNA1509_57451, RNA1509_8119, RNA1509_8271, RNA1509_893} {RNA1310_9962.1, RNA1509_19571, RNA1509_21722, RNA1509_28470, RNA1509_33241, RNA1509_57451, RNA1509_8119, RNA1509_8271, RNA1509_893} {RNA1509_19571, RNA1509_21722, RNA1509_28470, RNA1509_33241, RNA1509_57451, RNA1509_8119, RNA1509_8271, RNA1509_893, RNA815_3379.1}
81. MligTC455_19519 6580 137.09 Mlig455_046878

Neo: -

Age: -

GLUL 3.538 0.877 - 0.824 - 0.952 0.885 Mlig455_046878 {REF} {Length: 1555} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=56.6]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=52.0]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=508, Expect=4e-179]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=509, Expect=0.0]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=525, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=510, Expect=0.0]} {Smed: dd_Smed_v6_646_0_1, dd_Smed_v6_646_0_1, [RH, Score=566, Expect=0.0]} {RNA1509_506} {RNA1310_19328} {RNA815_7220.1}
82. MligTC455_40311 795 16.57 Mlig455_005646

Neo: -

Age: logFC(26M/2M)=-1.077

Region-enriched R4: 2.244/0.00079
Region-enriched R5: 1.789/0.00084

CYP2J2 3.506 0.918 - 0.742 - 0.953 0.893 Mlig455_005646 {REF} {Length: 2326} {Pfam: Cytochrome P450 [PF00067.24, score=345.0]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=303, Expect=4e-97]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=280, Expect=2e-88]; ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=1e-88]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=278, Expect=3e-87]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=276, Expect=8e-87]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=3e-85]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=271, Expect=1e-84]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=1e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=270, Expect=2e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=2e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=6e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=223, Expect=5e-66]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=249, Expect=1e-76]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=260, Expect=8e-81]} {RNA1509_32472} {RNA1310_10280} {RNA815_4805}
83. MligTC455_20359 2045 42.61 Mlig455_051099

Neo: -

Age: -

Region-enriched R3: 1.714/0.00720

SLC15A1 3.495 - 0.755 - 0.954 0.923 0.863 Mlig455_051099 {REF} {Length: 3010} {Pfam: POT family [PF00854.23, score=282.9]; Major Facilitator Superfamily [PF07690.18, score=26.5]; MFS/sugar transport protein [PF13347.8, score=17.7]} {Human: ENSG00000088386, SLC15A1, solute carrier family 15 member 1, [Score=351, Expect=7e-110]} {Mouse: ENSMUSG00000025557, Slc15a1, solute carrier family 15 (oligopeptide transporter), member 1, [Score=347, Expect=1e-108]; ENSMUSG00000022899, Slc15a2, solute carrier family 15 (H+/peptide transporter), member 2, [Score=332, Expect=2e-102]} {Dmel: FBgn0028491, CG2930, [Score=291, Expect=2e-86]} {Celegans: WBGene00003877, pept-1, Peptide transporter family 1, [RH, Score=271, Expect=4e-79]} {Smed: dd_Smed_v6_4941_0_1, dd_Smed_v6_4941_0_1, [RH, Score=449, Expect=1e-148]} {RNA1509_12523, RNA1509_2288, RNA1509_5660, RNA1509_7670, RNA1509_9453} {RNA1310_5104.2, RNA1509_12523, RNA1509_2288, RNA1509_5660, RNA1509_7670, RNA1509_9453} {RNA1509_12523, RNA1509_2288, RNA1509_5660, RNA1509_7670, RNA1509_9453, RNA815_1763.1}
84. MligTC455_12267 1146 23.88 Mlig455_020414

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.464

Region-enriched R4: 2.571/0.00351
Region-enriched R5: 1.608/0.04205

3.489 - - 0.811 0.967 0.821 0.890 Mlig455_020414 {REF} {Length: 1732} {Pfam: TATA element modulatory factor 1 DNA binding [PF12329.10, score=25.4]} {RNA1509_10012} {RNA1310_23404.1} {RNA815_8343.1}
85. MligTC455_19402 2412 50.25 Mlig455_008719

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-3.279

Region-enriched R5: 2.550/0.00012
Region-enriched R4: 2.406/0.00443
Region-enriched R6: 2.168/0.01405

3.477 0.837 - 0.894 0.952 0.794 - Mlig455_008719 {REF} {Length: 2893} {RNA1509_37537} {RNA1310_2374.1} {RNA815_13234}
86. MligTC455_34616 3872 80.67 Mlig455_059218

Neo: -

Age: logFC(26M/2M)=0.164

Region-enriched R5: 1.338/0.00001

3.477 - 0.764 - 0.974 0.928 0.811 Mlig455_059218 {REF} {Length: 4460} {Pfam: Prominin [PF05478.13, score=45.9]} {RNA1509_1005, RNA1509_11837, RNA1509_18876, RNA1509_33587, RNA1509_4880} {RNA1310_2600.2, RNA1509_1005, RNA1509_11837, RNA1509_18876, RNA1509_33587, RNA1509_4880} {RNA1509_1005, RNA1509_11837, RNA1509_18876, RNA1509_33587, RNA1509_4880, RNA815_771}
87. MligTC455_48796 3932 81.93 Mlig455_010032, Mlig455_063287

Neo: -

Age: -

Region-enriched R3: 1.371/0.00023

3.451 0.819 - - 0.962 0.746 0.924

Mlig455_010032 {REF} {Length: 3305} {TRANSSPLICED} {Dmel: FBgn0051195, CG31195, [RH, Score=445, Expect=3e-143]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [RH, Score=727, Expect=0.0]} {RNA1509_1610, RNA1509_26475} {RNA1310_2842, RNA1509_1610, RNA1509_26475} {RNA1509_1610, RNA1509_26475, RNA815_1220.1}

Mlig455_063287 {REF} {Length: 3306} {TRANSSPLICED} {Dmel: FBgn0051195, CG31195, [RH, Score=445, Expect=4e-143]} {Smed: dd_Smed_v6_2407_0_1, dd_Smed_v6_2407_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_1610} {RNA1310_2842} {RNA815_1220.1}
88. MligTC455_45334 2178 45.38 Mlig455_068883

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.795/0.00015
Region-enriched R3: 1.326/0.00189
Region-enriched R5: 1.022/0.01242

LIPA 3.432 0.742 - - 0.954 0.854 0.882 Mlig455_068883 {REF} {Length: 2253} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=88.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=54.0]; Serine aminopeptidase, S33 [PF12146.10, score=47.6]; Alpha/beta hydrolase family [PF12697.9, score=30.4]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=323, Expect=2e-106]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=322, Expect=5e-106]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=312, Expect=3e-102]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=320, Expect=2e-105]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=315, Expect=1e-103]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=308, Expect=1e-100]} {Dmel: FBgn0032264, Lip4, Lipase 4, [RH, Score=265, Expect=1e-83]} {Celegans: WBGene00021963, lipl-6, LIPase Like, [RH, Score=295, Expect=9e-94]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=360, Expect=2e-121]} {RNA1509_16913, RNA1509_19422, RNA1509_39468} {RNA1310_10300.2, RNA1509_16913, RNA1509_19422, RNA1509_39468} {RNA1509_16913, RNA1509_19422, RNA1509_39468, RNA815_4697}
89. MligTC455_45333 5039 104.98 Mlig455_024662, Mlig455_048643, Mlig455_068867

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.566/0.00006
Region-enriched R3: 1.419/0.00002

LIPA 3.431 0.757 - - 0.958 0.822 0.894

Mlig455_024662 {REF} {Length: 2228} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}

Mlig455_048643 {REF} {Length: 2232} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}

Mlig455_068867 {REF} {Length: 4154} {TRANSSPLICED} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}
90. MligTC455_50036 1353 28.19 Mlig455_063714

Neo: -

Age: logFC(26M/2M)=-0.294

Region-enriched R4: 1.826/0.00071
Region-enriched R3: 1.745/0.00078
Region-enriched R5: 1.202/0.01353

SPHK1 3.426 - - 0.704 0.876 0.887 0.959 Mlig455_063714 {REF} {Length: 3647} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=81.8]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [Score=152, Expect=4e-43]} {Mouse: ENSMUSG00000061878, Sphk1, sphingosine kinase 1, [RH, Score=150, Expect=5e-44]; ENSMUSG00000057342, Sphk2, sphingosine kinase 2, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [RH, Score=145, Expect=1e-39]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [Score=120, Expect=2e-31]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [Score=127, Expect=3e-34]} {RNA1509_19326} {RNA1310_4471} {RNA815_1161}
91. MligTC455_50035 432 9 Mlig455_000039

Neo: -

Age: Up-Down-Up

Region-enriched R4: 2.574/0.01215

SPHK1 3.392 - 0.702 - 0.848 0.882 0.960 Mlig455_000039 {REF} {Length: 2459} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=79.4]; YegS C-terminal NAD kinase beta sandwich-like domain [PF19279.1, score=29.9]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [RH, Score=215, Expect=5e-64]} {Mouse: ENSMUSG00000061878, Sphk1, sphingosine kinase 1, [RH, Score=206, Expect=1e-60]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [Score=142, Expect=1e-35]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [RH, Score=149, Expect=5e-39]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [RH, Score=174, Expect=1e-48]} {RNA1509_19326} {RNA1310_4471} {RNA815_1161}
92. MligTC455_35218 678 14.12 Mlig455_014318

Neo: -

Age: Down-Up-Up

3.333 0.958 - - 0.710 0.827 0.838 Mlig455_014318 {REF} {Length: 1896} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=159.5]} {RNA1509_21563, RNA1509_4768} {RNA1310_7742.1, RNA1509_21563, RNA1509_4768} {RNA1509_21563, RNA1509_4768, RNA815_6411}
93. MligTC455_53355 1190 24.78 Mlig455_033338, Mlig455_033357

Neo: -

Age: -

Region-enriched R4: 1.851/0.00149

3.314 0.753 - - 0.951 0.757 0.853

Mlig455_033338 {REF} {Length: 1291} {RNA1509_14712, RNA1509_46611} {RNA1310_36401.2, RNA1509_46611} {RNA1509_46611, RNA815_17710}

Mlig455_033357 {REF} {Length: 973} {TRANSSPLICED} {RNA1509_14712} {RNA1310_36401.2} {RNA815_17710}
94. MligTC455_42846 590 12.29 Mlig455_010478, Mlig455_061899

Neo: -

Age: -

Region-enriched R4: 2.602/0.01388
Region-enriched R3: 2.177/0.04474

AGMO 3.291 0.780 - 0.778 0.957 0.776 -

Mlig455_010478 {REF} {Length: 1782} {Pfam: Fatty acid hydroxylase superfamily [PF04116.15, score=95.8]} {Human: ENSG00000187546, AGMO, alkylglycerol monooxygenase, [RH, Score=370, Expect=1e-124]} {Mouse: ENSMUSG00000050103, Agmo, alkylglycerol monooxygenase, [RH, Score=377, Expect=7e-128]} {Celegans: WBGene00007210, agmo-1, Alkylglycerol monooxygenase, [RH, Score=273, Expect=2e-86]} {Smed: dd_Smed_v6_3673_0_1, dd_Smed_v6_3673_0_1, [RH, Score=368, Expect=5e-125]} {RNA1509_14794} {RNA1310_15779} {RNA815_5967}

Mlig455_061899 {REF} {Length: 1846} {Pfam: Fatty acid hydroxylase superfamily [PF04116.15, score=81.1]} {Human: ENSG00000187546, AGMO, alkylglycerol monooxygenase, [Score=273, Expect=4e-87]} {Mouse: ENSMUSG00000050103, Agmo, alkylglycerol monooxygenase, [Score=279, Expect=7e-90]} {Celegans: WBGene00007210, agmo-1, Alkylglycerol monooxygenase, [Score=181, Expect=1e-51]} {Smed: dd_Smed_v6_3673_0_1, dd_Smed_v6_3673_0_1, [Score=272, Expect=5e-88]} {RNA1509_14794} {RNA1310_15779} {RNA815_5967}
95. MligTC455_33319 4306 89.7 Mlig455_027532

Neo: -

Age: logFC(26M/2M)=1.169

Region-enriched R3: 1.852/0.00003
Region-enriched R5: 1.035/0.02995

STS 3.276 0.771 0.835 0.702 - 0.968 - Mlig455_027532 {REF} {Length: 2207} {TRANSSPLICED} {Pfam: Sulfatase [PF00884.25, score=269.3]; C-terminal region of aryl-sulfatase [PF14707.8, score=89.8]; Type I phosphodiesterase / nucleotide pyrophosphatase [PF01663.24, score=34.8]} {Human: ENSG00000101846, STS, steroid sulfatase, [RH, Score=474, Expect=2e-161]} {Mouse: ENSMUSG00000022620, Arsa, arylsulfatase A, [Score=194, Expect=7e-55]} {Dmel: FBgn0036765, CG7408, [Score=124, Expect=7e-30]} {Celegans: WBGene00006309, sul-2, SULfatase domain protein, [Score=131, Expect=6e-33]} {RNA1509_15815, RNA1509_18792, RNA1509_22490, RNA1509_49410} {RNA1310_7885.2, RNA1509_15815, RNA1509_18792, RNA1509_22490, RNA1509_49410} {RNA1509_15815, RNA1509_18792, RNA1509_22490, RNA1509_49410, RNA815_3164.1}
96. MligTC455_11112 617 12.86 Mlig455_008574

Neo: -

Age: logFC(26M/2M)=0.279

Region-enriched R4: 2.218/0.00591
Region-enriched R5: 1.831/0.00200

3.24 0.740 - - 0.972 0.760 0.768 Mlig455_008574 {REF} {Length: 473} {NoTransDecoderORF} {RNA1509_284} {RNA1310_11148} {RNA815_6153}
97. MligTC455_23343 6086 126.8 Mlig455_000655

Neo: -

Age: -

Region-enriched R5: 1.092/0.00604

3.232 - 0.717 - 0.743 0.813 0.959 Mlig455_000655 {REF} {Length: 1890} {TRANSSPLICED} {Pfam: Dyp-type peroxidase family [PF04261.14, score=113.7]} {Smed: dd_Smed_v6_2999_0_1, dd_Smed_v6_2999_0_1, [RH, Score=350, Expect=5e-119]} {RNA1509_10815, RNA1509_11142, RNA1509_1189, RNA1509_13453, RNA1509_20781, RNA1509_26674, RNA1509_37792, RNA1509_44529, RNA1509_52947, RNA1509_5910} {RNA1310_10944, RNA1509_10815, RNA1509_11142, RNA1509_1189, RNA1509_13453, RNA1509_20781, RNA1509_26674, RNA1509_37792, RNA1509_44529, RNA1509_52947, RNA1509_5910} {RNA1509_10815, RNA1509_11142, RNA1509_1189, RNA1509_13453, RNA1509_20781, RNA1509_26674, RNA1509_37792, RNA1509_44529, RNA1509_52947, RNA1509_5910, RNA815_5709}
98. MligTC455_50629 5381 112.09 Mlig455_059833

Neo: -

Age: -

Region-enriched R3: 1.247/0.03085

3.211 0.715 0.785 0.755 0.956 - - Mlig455_059833 {REF} {Length: 1487} {TRANSSPLICED} {Pfam: Universal stress protein family [PF00582.28, score=83.7]} {Smed: dd_Smed_v6_1092_0_1, dd_Smed_v6_1092_0_1, [Score=134, Expect=1e-40]} {RNA1509_10520, RNA1509_1843, RNA1509_7904} {RNA1310_5062.2, RNA1509_10520, RNA1509_1843, RNA1509_7904} {RNA1509_10520, RNA1509_1843, RNA1509_7904, RNA815_2234.1}
99. MligTC455_16257 1877 39.1 Mlig455_026808, Mlig455_030881

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.209/0.00209
Region-enriched R3: 1.663/0.01717
Region-enriched R5: 1.364/0.02606

STOM 2.762 - - - 0.951 0.885 0.926

Mlig455_026808 {REF} {Length: 1301} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=20.6]} {Human: ENSG00000148175, STOM, stomatin, [Score=123, Expect=2e-35]; ENSG00000133115, STOML3, stomatin like 3, [Score=118, Expect=1e-33]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=123, Expect=2e-35]; ENSMUSG00000027744, Stoml3, stomatin (Epb7.2)-like 3, [Score=120, Expect=2e-34]; ENSMUSG00000026602, Nphs2, nephrosis 2, podocin, [Score=117, Expect=2e-32]} {Dmel: FBgn0260657, CG42540, [Score=126, Expect=5e-36]} {Celegans: WBGene00006068, sto-6, STOmatin, [Score=140, Expect=1e-42]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=148, Expect=1e-45]} {RNA1509_6816} {RNA1310_26895} {RNA815_11983}

Mlig455_030881 {REF} {Length: 1405} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=110.3]; SPFH domain-Band 7 family [PF13421.8, score=20.7]} {Human: ENSG00000148175, STOM, stomatin, [Score=335, Expect=3e-115]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=323, Expect=5e-111]} {Dmel: FBgn0260657, CG42540, [Score=323, Expect=2e-109]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=335, Expect=4e-114]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=362, Expect=1e-126]} {RNA1509_6816} {RNA1310_26895, RNA1509_6816} {RNA1509_6816, RNA815_11983}
100. MligTC455_27756 2766 57.63 Mlig455_036299, Mlig455_036313

Neo: -

Age: logFC(26M/2M)=0.266

Region-enriched R3: 1.773/0.00001
Region-enriched R4: 1.368/0.00784

AF241726.2, TSPAN7 2.762 - - - 0.908 0.904 0.950

Mlig455_036299 {REF} {Length: 1664} {Pfam: Tetraspanin family [PF00335.22, score=86.9]} {Human: ENSG00000250349, AF241726.2, novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein, [Score=63.2, Expect=7e-11]; ENSG00000156298, TSPAN7, tetraspanin 7, [Score=62.8, Expect=8e-11]} {Mouse: ENSMUSG00000058254, Tspan7, tetraspanin 7, [Score=61.6, Expect=1e-10]; ENSMUSG00000067377, Tspan6, tetraspanin 6, [Score=59.3, Expect=7e-10]} {Celegans: WBGene00023491, tsp-21, Tetraspanin, [Score=50.4, Expect=5e-07]} {Smed: dd_Smed_v6_854_1_1, dd_Smed_v6_854_1_1, [Score=109, Expect=3e-28]} {RNA1509_20407} {RNA1310_5241, RNA1509_20407} {RNA1509_20407, RNA815_7978}

Mlig455_036313 {REF} {Length: 3246} {Pfam: Tetraspanin family [PF00335.22, score=139.9]} {Human: ENSG00000156298, TSPAN7, tetraspanin 7, [Score=62.4, Expect=6e-10]; ENSG00000250349, AF241726.2, novel proline rich Gla (G-carboxyglutamic acid) 1 (PRRG1) and tetraspanin 7 (TSPAN7) protein, [Score=60.5, Expect=3e-09]} {Mouse: ENSMUSG00000058254, Tspan7, tetraspanin 7, [Score=61.6, Expect=6e-10]} {Smed: dd_Smed_v6_854_1_1, dd_Smed_v6_854_1_1, [Score=107, Expect=9e-26]} {RNA1509_20407} {RNA1310_5241} {RNA815_7978}

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