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Results for MligTC455_35633

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_35633 4966 103.45 Mlig455_048471

Neo: -

Age: -

Region-enriched R4: 1.579/0.00682
Region-enriched R3: 1.493/0.00762

DHDH Mlig455_048471 {REF} {Length: 1491} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=87.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]; Homoserine dehydrogenase, NAD binding domain [PF03447.18, score=19.9]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=246, Expect=3e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=248, Expect=4e-80]} {Dmel: FBgn0031418, CG3609, [RH, Score=231, Expect=1e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=213, Expect=9e-67]} {RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1310_24236, RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1509_1049, RNA1509_4889, RNA1509_8979, RNA815_11111.1}

Cumulative graph for MligTC455_35633

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.297 6.836 0.03841 0.47951
RegionR2 -2.201 6.836 0.00007 0.00306
RegionR3 1.493 6.836 0.00018 0.00762
RegionR4 1.579 6.836 0.00059 0.00682
RegionR5 1.043 6.836 0.00943 0.05531
RegionR6 0.579 6.836 0.17639 0.73816
RegionR7 -2.389 6.836 0.00004 0.00258
RegionR8 -1.399 6.836 0.02184 0.28848

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.413 6.836 0.08726 0.79173
RegenerationR2 0.078 6.836 0.89152 1.00000
RegenerationR3 -0.586 6.836 0.28488 0.71663
RegenerationR4 -0.251 6.836 0.65881 0.93782
RegenerationR5 -0.164 6.836 0.76384 0.97662
RegenerationR6 -0.029 6.836 0.95836 1.00000
RegenerationBL 0.268 6.836 0.60954 0.95515
RegenerationTP 0.375 6.836 0.52443 0.91658


Genes with expression patterns similar to MligTC455_35633

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_35633 4966 103.45 Mlig455_048471

Neo: -

Age: -

Region-enriched R4: 1.579/0.00682
Region-enriched R3: 1.493/0.00762

DHDH 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_048471 {REF} {Length: 1491} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=87.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]; Homoserine dehydrogenase, NAD binding domain [PF03447.18, score=19.9]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=246, Expect=3e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=248, Expect=4e-80]} {Dmel: FBgn0031418, CG3609, [RH, Score=231, Expect=1e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=213, Expect=9e-67]} {RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1310_24236, RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1509_1049, RNA1509_4889, RNA1509_8979, RNA815_11111.1}
2. MligTC455_22594 11907 248.06 Mlig455_000659

Neo: -

Age: -

Region-enriched R3: 1.649/0.00345
Region-enriched R6: 1.411/0.04025
Region-enriched R5: 1.370/0.00986

FTH1 5.393 0.893 0.865 0.806 0.890 0.996 0.943 Mlig455_000659 {REF} {Length: 4971} {Pfam: Ferritin-like domain [PF00210.26, score=121.4]; Rubrerythrin [PF02915.19, score=26.2]} {Human: ENSG00000167996, FTH1, ferritin heavy chain 1, [Score=131, Expect=3e-38]} {Mouse: ENSMUSG00000024661, Fth1, ferritin heavy polypeptide 1, [Score=127, Expect=4e-37]; ENSMUSG00000024510, Ftmt, ferritin mitochondrial, [Score=123, Expect=7e-35]} {Dmel: FBgn0030449, Fer3HCH, Ferritin 3 heavy chain homologue, [Score=127, Expect=4e-37]} {Celegans: WBGene00001501, ftn-2, Ferritin, [Score=134, Expect=5e-40]} {Smed: dd_Smed_v6_3974_0_1, dd_Smed_v6_3974_0_1, [Score=143, Expect=1e-43]} {RNA1509_1543, RNA1509_3403, RNA1509_3412, RNA1509_36561, RNA1509_39647, RNA1509_51397, RNA1509_5479} {RNA1310_294, RNA1509_1543, RNA1509_3403, RNA1509_3412, RNA1509_36561, RNA1509_39647, RNA1509_51397} {RNA1509_1543, RNA1509_3403, RNA1509_3412, RNA1509_36561, RNA1509_39647, RNA1509_51397, RNA815_755}
3. MligTC455_21475 15839 329.98 Mlig455_064237

Neo: -

Age: logFC(26M/2M)=0.290

Region-enriched R3: 2.133/0.00005

CTSV 5.345 0.900 0.822 0.848 0.982 0.889 0.904 Mlig455_064237 {REF} {Length: 2670} {Pfam: Papain family cysteine protease [PF00112.25, score=291.7]; Cathepsin propeptide inhibitor domain (I29) [PF08246.14, score=54.9]; Peptidase C1-like family [PF03051.17, score=27.5]} {Human: ENSG00000136943, CTSV, cathepsin V, [RH, Score=358, Expect=3e-123]; ENSG00000135047, CTSL, cathepsin L, [RH, Score=356, Expect=2e-122]} {Mouse: ENSMUSG00000021477, Ctsl, cathepsin L, [RH, Score=348, Expect=9e-120]; ENSMUSG00000042243, BC051665, cDNA sequence BC051665, [RH, Score=335, Expect=1e-114]; ENSMUSG00000056728, Ctsll3, cathepsin L-like 3, [RH, Score=333, Expect=2e-113]} {Dmel: FBgn0013770, Cp1, Cysteine proteinase-1, [Score=359, Expect=6e-124]} {Celegans: WBGene00000776, cpl-1, CathePsin L family, [RH, Score=336, Expect=6e-115]} {Smed: dd_Smed_v6_48_0_1, dd_Smed_v6_48_0_1, [RH, Score=428, Expect=2e-151]} {RNA1509_124, RNA1509_29064, RNA1509_51476, RNA1509_81} {RNA1310_16613, RNA1509_29064, RNA1509_51476, RNA1509_81} {RNA1509_29064, RNA1509_51476, RNA1509_81, RNA815_7527}
4. MligTC455_46304 5253 109.45 Mlig455_047938

Neo: -

Age: -

Region-enriched R4: 1.799/0.00000
Region-enriched R3: 1.541/0.00001
Region-enriched R5: 1.139/0.00155

MGST1 5.333 0.878 0.864 0.930 0.785 0.915 0.961 Mlig455_047938 {REF} {Length: 721} {TRANSSPLICED} {Pfam: MAPEG family [PF01124.20, score=74.9]} {Human: ENSG00000008394, MGST1, microsomal glutathione S-transferase 1, [RH, Score=146, Expect=2e-45]} {Mouse: ENSMUSG00000008540, Mgst1, microsomal glutathione S-transferase 1, [RH, Score=150, Expect=3e-47]} {Dmel: FBgn0025814, Mgstl, Microsomal glutathione S-transferase-like, [RH, Score=127, Expect=5e-38]} {RNA1509_13231, RNA1509_3817, RNA1509_42261, RNA1509_45247, RNA1509_47449, RNA1509_7161, RNA1509_9208} {RNA1310_49001.1, RNA1509_13231, RNA1509_3817, RNA1509_42261, RNA1509_45247, RNA1509_47449, RNA1509_7161, RNA1509_9208} {RNA1509_13231, RNA1509_3817, RNA1509_42261, RNA1509_45247, RNA1509_47449, RNA1509_7161, RNA1509_9208, RNA815_18438}
5. MligTC455_49488 5075 105.73 Mlig455_055474

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.341

Region-enriched R3: 1.609/0.02116

5.331 0.801 0.813 0.845 0.967 0.963 0.942 Mlig455_055474 {REF} {Length: 988} {Pfam: Universal stress protein family [PF00582.28, score=100.4]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=126, Expect=2e-37]} {RNA1509_12747, RNA1509_15238} {RNA1310_22621, RNA1509_15238} {RNA1509_15238, RNA815_17247}
6. MligTC455_49487 5068 105.57 Mlig455_036283

Neo: -

Age: logFC(26M/2M)=-0.424

Region-enriched R3: 1.606/0.02613

5.328 0.801 0.813 0.846 0.966 0.959 0.943 Mlig455_036283 {REF} {Length: 978} {Pfam: Universal stress protein family [PF00582.28, score=89.7]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=109, Expect=3e-31]} {RNA1509_12747} {RNA1310_22621} {RNA815_17247}
7. MligTC455_53810 10368 216.01 Mlig455_015254

Neo: -

Age: logFC(26M/2M)=-0.519

Region-enriched R3: 1.584/0.00569
Region-enriched R5: 1.232/0.02515

SULT1C4 5.325 0.804 0.906 0.855 0.976 0.927 0.857 Mlig455_015254 {REF} {Length: 3712} {Pfam: Sulfotransferase domain [PF00685.29, score=172.2]; Sulfotransferase family [PF13469.8, score=31.5]} {Human: ENSG00000198075, SULT1C4, sulfotransferase family 1C member 4, [Score=168, Expect=6e-50]; ENSG00000198203, SULT1C2, sulfotransferase family 1C member 2, [Score=167, Expect=7e-50]} {Mouse: ENSMUSG00000023122, Sult1c2, sulfotransferase family, cytosolic, 1C, member 2, [Score=163, Expect=3e-48]} {Dmel: FBgn0034887, St1, Sulfotransferase 1, [Score=111, Expect=2e-28]} {Celegans: WBGene00013748, ssu-1, Suppressor of Stomatin mutant Uncoordination, [Score=99.0, Expect=2e-23]} {Smed: dd_Smed_v6_4622_0_1, dd_Smed_v6_4622_0_1, [Score=152, Expect=1e-44]} {RNA1509_178, RNA1509_182} {RNA1310_14124, RNA1509_178, RNA1509_182} {RNA1509_178, RNA1509_182, RNA815_6793}
8. MligTC455_24086 11442 238.37 Mlig455_068330

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.329/0.00000
Region-enriched R6: 1.493/0.00384
Region-enriched R5: 1.266/0.00365

ACHE 5.26 0.914 0.845 0.768 0.962 0.940 0.831 Mlig455_068330 {REF} {Length: 2275} {Pfam: Carboxylesterase family [PF00135.30, score=340.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=228, Expect=5e-66]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=226, Expect=1e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=191, Expect=1e-52]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=226, Expect=1e-65]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=202, Expect=4e-57]} {RNA1509_2293, RNA1509_46106} {RNA1310_10437.1, RNA1509_2293} {RNA1509_2293, RNA815_3976}
9. MligTC455_22665 6992 145.67 Mlig455_034131

Neo: -

Age: -

Region-enriched R3: 2.453/0.00000
Region-enriched R5: 1.399/0.00383
Region-enriched R4: 1.286/0.03665

ACE 5.222 0.855 0.769 0.898 0.958 0.874 0.868 Mlig455_034131 {REF} {Length: 2725} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=702.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=523, Expect=3e-171]; ENSG00000264813, AC113554.1, novel transcript, [RH, Score=518, Expect=2e-175]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=526, Expect=6e-172]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [RH, Score=456, Expect=7e-153]} {Smed: dd_Smed_v6_6160_0_1, dd_Smed_v6_6160_0_1, [Score=399, Expect=7e-131]} {RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1310_5722, RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1509_2364, RNA1509_2955, RNA1509_47766, RNA815_3600}
10. MligTC455_49519 17930 373.55 Mlig455_030984

Neo: -

Age: logFC(26M/2M)=0.549

Region-enriched R3: 2.084/0.00003

HPGDS 5.193 0.860 0.812 0.896 0.976 0.928 0.721 Mlig455_030984 {REF} {Length: 859} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=61.6]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=46.9]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=28.2]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [RH, Score=106, Expect=9e-28]} {Mouse: ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [RH, Score=93.6, Expect=4e-23]} {Dmel: FBgn0010226, GstS1, Glutathione S transferase S1, [Score=90.1, Expect=2e-21]} {Celegans: WBGene00001753, gst-5, Probable glutathione S-transferase 5, [RH, Score=112, Expect=3e-30]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [RH, Score=187, Expect=8e-60]} {RNA1509_12904, RNA1509_271, RNA1509_888} {RNA1310_36360, RNA1509_12904, RNA1509_888} {RNA1509_12904, RNA1509_888, RNA815_14903.1}
11. MligTC455_37114 9548 198.91 Mlig455_020763

Neo: -

Age: -

Region-enriched R3: 1.051/0.01206

LGMN 5.145 0.864 0.859 0.749 0.970 0.787 0.916 Mlig455_020763 {REF} {Length: 1971} {Pfam: Peptidase C13 family [PF01650.20, score=360.1]} {Human: ENSG00000100600, LGMN, legumain, [RH, Score=386, Expect=4e-131]} {Mouse: ENSMUSG00000021190, Lgmn, legumain, [RH, Score=391, Expect=4e-133]} {Dmel: FBgn0023545, PIG-K, Phosphatidylinositol glycan anchor biosynthesis class K, [Score=126, Expect=2e-32]} {Celegans: WBGene00012144, T28H10.3, [RH, Score=323, Expect=2e-106]} {Smed: dd_Smed_v6_6456_0_1, dd_Smed_v6_6456_0_1, [Score=104, Expect=5e-25]} {RNA1509_4583} {RNA1310_13933, RNA1509_4583} {RNA1509_4583, RNA815_6243.1}
12. MligTC455_42352 5331 111.06 Mlig455_014325

Neo: -

Age: -

Region-enriched R3: 1.607/0.00131
Region-enriched R5: 1.102/0.02723

ACE 5.145 0.799 0.791 0.801 0.960 0.869 0.925 Mlig455_014325 {REF} {Length: 2705} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441, RNA1509_9027} {RNA1310_8949, RNA1509_441, RNA1509_9027} {RNA1509_441, RNA1509_9027, RNA815_4061}
13. MligTC455_31825 3098 64.55 Mlig455_047151

Neo: -

Age: -

Region-enriched R3: 1.610/0.00965
Region-enriched R4: 1.361/0.04740
Region-enriched R5: 1.152/0.04924

5.132 0.872 0.763 0.821 0.952 0.888 0.836 Mlig455_047151 {REF} {Length: 1650} {Pfam: VDE lipocalin domain [PF07137.13, score=61.0]} {RNA1509_31696, RNA1509_3758, RNA1509_5185} {RNA1310_14334.2, RNA1509_31696, RNA1509_3758, RNA1509_5185} {RNA1509_31696, RNA1509_3758, RNA1509_5185, RNA815_7820}
14. MligTC455_15686 5588 116.41 Mlig455_011058

Neo: -

Age: -

Region-enriched R3: 1.651/0.01200
Region-enriched R5: 1.436/0.01547

CRABP2 5.108 0.915 0.742 0.853 0.750 0.898 0.950 Mlig455_011058 {REF} {Length: 857} {Pfam: Lipocalin / cytosolic fatty-acid binding protein family [PF00061.25, score=54.9]; Lipocalin / cytosolic fatty-acid binding protein family [PF14651.8, score=29.1]} {Human: ENSG00000143320, CRABP2, cellular retinoic acid binding protein 2, [Score=95.5, Expect=1e-25]; ENSG00000170323, FABP4, fatty acid binding protein 4, [Score=91.7, Expect=3e-24]; ENSG00000121769, FABP3, fatty acid binding protein 3, [Score=91.3, Expect=4e-24]} {Mouse: ENSMUSG00000004885, Crabp2, cellular retinoic acid binding protein II, [Score=95.9, Expect=5e-26]; ENSMUSG00000027533, Fabp5, fatty acid binding protein 5, epidermal, [Score=93.2, Expect=5e-25]; ENSMUSG00000028773, Fabp3, fatty acid binding protein 3, muscle and heart, [Score=92.4, Expect=1e-24]} {Dmel: FBgn0037913, fabp, fatty acid binding protein, [Score=76.6, Expect=1e-18]} {Celegans: WBGene00002257, lbp-5, Fatty acid-binding protein homolog 5, [Score=100, Expect=6e-28]} {Smed: dd_Smed_v6_271_0_1, dd_Smed_v6_271_0_1, [RH, Score=102, Expect=6e-29]} {RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404} {RNA1310_38135.2, RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404} {RNA1509_23333, RNA1509_23783, RNA1509_29966, RNA1509_3321, RNA1509_6404, RNA815_30164}
15. MligTC455_38469 2237 46.61 Mlig455_028190, Mlig455_063554

Neo: -

Age: logFC(26M/2M)=0.551

Region-enriched R4: 2.765/0.00002
Region-enriched R3: 2.517/0.00000
Region-enriched R5: 1.859/0.00156

MFSD2A 5.103 0.846 0.738 0.737 0.948 0.883 0.951

Mlig455_028190 {REF} {Length: 1877} {Pfam: MFS/sugar transport protein [PF13347.8, score=314.5]; Major Facilitator Superfamily [PF07690.18, score=35.3]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=317, Expect=2e-101]} {Mouse: ENSMUSG00000028655, Mfsd2a, major facilitator superfamily domain containing 2A, [RH, Score=312, Expect=2e-99]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [RH, Score=380, Expect=3e-126]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}

Mlig455_063554 {REF} {Length: 2339} {Pfam: MFS/sugar transport protein [PF13347.8, score=217.9]; Major Facilitator Superfamily [PF07690.18, score=39.9]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=223, Expect=1e-68]} {Mouse: ENSMUSG00000037336, Mfsd2b, major facilitator superfamily domain containing 2B, [RH, Score=212, Expect=2e-64]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [Score=274, Expect=8e-87]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}
16. MligTC455_24083 6997 145.77 Mlig455_007319

Neo: -

Age: -

Region-enriched R3: 2.037/0.00010
Region-enriched R5: 1.165/0.04106

ACHE 5.053 0.767 0.760 0.916 0.750 0.901 0.959 Mlig455_007319 {REF} {Length: 2399} {Pfam: Carboxylesterase family [PF00135.30, score=344.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=233, Expect=9e-68]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=225, Expect=3e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=183, Expect=6e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=228, Expect=1e-66]} {Smed: dd_Smed_v6_4800_0_1, dd_Smed_v6_4800_0_1, [Score=184, Expect=4e-50]} {RNA1509_195, RNA1509_4270, RNA1509_51012} {RNA1310_9229, RNA1509_4270, RNA1509_51012} {RNA1509_4270, RNA1509_51012, RNA815_3141.1}
17. MligTC455_34295 1251 26.06 Mlig455_039417

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-1.176

Region-enriched R3: 2.357/0.00048
Region-enriched R4: 1.872/0.01857

5.029 0.751 0.906 0.779 0.929 0.714 0.950 Mlig455_039417 {REF} {Length: 666} {RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827} {RNA1310_54443, RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827} {RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827, RNA815_29054}
18. MligTC455_36664 2276 47.42 Mlig455_005884

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.400

Region-enriched R3: 1.625/0.01190

PSAP 4.988 0.760 0.719 0.712 0.936 0.966 0.895 Mlig455_005884 {REF} {Length: 3972} {Pfam: Saposin-like type B, region 1 [PF05184.17, score=380.3]; Saposin-like type B, region 2 [PF03489.19, score=358.9]; Homeodomain-like domain [PF13384.8, score=54.4]; Helix-turn-helix domain [PF13518.8, score=42.8]; Saposin A-type domain [PF02199.17, score=33.9]; Protein of unknown function (DUF2753) [PF10952.10, score=33.0]; Replication factor RFC1 C terminal domain [PF08519.14, score=29.4]; Winged helix-turn helix [PF13551.8, score=25.9]; HD domain [PF13023.8, score=24.1]; Putative transmembrane protein [PF10271.11, score=24.0]; Delta endotoxin [PF18449.3, score=20.2]; DNA replication factor Cdt1 C-terminal domain [PF16679.7, score=19.5]} {Human: ENSG00000197746, PSAP, prosaposin, [RH, Score=184, Expect=6e-49]} {Mouse: ENSMUSG00000004207, Psap, prosaposin, [RH, Score=162, Expect=1e-41]} {Dmel: FBgn0000416, Sap-r, Saposin-related, [RH, Score=237, Expect=2e-64]} {Smed: dd_Smed_v6_266_0_1, dd_Smed_v6_266_0_1, [Score=97.8, Expect=2e-22]} {RNA1509_1917} {RNA1310_3003.1} {RNA815_5033.1}
19. MligTC455_25457 2491 51.89 Mlig455_028995

Neo: -

Age: logFC(26M/2M)=-0.222

Region-enriched R3: 1.404/0.00023

ABCB1 4.91 0.812 0.780 0.746 0.784 0.951 0.837 Mlig455_028995 {REF} {Length: 8120} {Pfam: ABC transporter transmembrane region [PF00664.25, score=423.8]; ABC transporter [PF00005.29, score=235.2]; RecF/RecN/SMC N terminal domain [PF02463.21, score=64.3]; AAA ATPase domain [PF13191.8, score=45.9]; Predicted ATPase of the ABC class [PF09818.11, score=32.2]; P-loop containing region of AAA domain [PF13555.8, score=30.3]; AAA domain [PF13401.8, score=29.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=29.3]; RsgA GTPase [PF03193.18, score=27.5]; AAA domain [PF13238.8, score=24.6]; AAA domain (dynein-related subfamily) [PF07728.16, score=23.8]; Rad17 P-loop domain [PF03215.17, score=22.6]; AAA domain [PF13521.8, score=21.1]; P-loop containing dynein motor region [PF12775.9, score=20.6]; Zeta toxin [PF06414.14, score=20.5]; AAA domain [PF13481.8, score=20.5]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=20.1]; Protein of unknown function (DUF815) [PF05673.15, score=19.9]; AAA domain [PF13604.8, score=19.6]; Cytidylate kinase [PF02224.20, score=18.7]} {Human: ENSG00000085563, ABCB1, ATP binding cassette subfamily B member 1, [Score=1139, Expect=0.0]; ENSG00000005471, ABCB4, ATP binding cassette subfamily B member 4, [Score=1095, Expect=0.0]} {Mouse: ENSMUSG00000040584, Abcb1a, ATP-binding cassette, sub-family B (MDR/TAP), member 1A, [Score=1136, Expect=0.0]; ENSMUSG00000028970, Abcb1b, ATP-binding cassette, sub-family B (MDR/TAP), member 1B, [Score=1123, Expect=0.0]; ENSMUSG00000042476, Abcb4, ATP-binding cassette, sub-family B (MDR/TAP), member 4, [Score=1090, Expect=0.0]} {Dmel: FBgn0010241, Mdr50, Multi drug resistance 50, [RH, Score=865, Expect=0.0]} {Celegans: WBGene00004003, pgp-9, P-GlycoProtein related, [Score=1080, Expect=0.0]} {Smed: dd_Smed_v6_4124_0_1, dd_Smed_v6_4124_0_1, [Score=932, Expect=0.0]} {RNA1509_2606, RNA1509_35960} {RNA1310_1852.1, RNA1509_2606, RNA1509_35960} {RNA1509_2606, RNA1509_35960, RNA815_526.1}
20. MligTC455_46181 2902 60.45 Mlig455_054291

Neo: -

Age: logFC(26M/2M)=-0.282

Region-enriched R4: 1.689/0.00164
Region-enriched R3: 1.207/0.03875
Region-enriched R5: 1.162/0.01606

4.598 - 0.850 0.886 0.961 0.964 0.937 Mlig455_054291 {REF} {Length: 934} {Pfam: Universal stress protein family [PF00582.28, score=107.5]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=119, Expect=8e-35]} {RNA1509_5080} {RNA1310_45709, RNA1509_5080} {RNA1509_5080, RNA815_23470}
21. MligTC455_37113 9210 191.88 Mlig455_020693

Neo: -

Age: -

Region-enriched R3: 1.525/0.00009

LGMN 4.581 0.938 0.894 - 0.966 0.873 0.910 Mlig455_020693 {REF} {Length: 3890} {Pfam: Peptidase C13 family [PF01650.20, score=361.0]} {Human: ENSG00000100600, LGMN, legumain, [RH, Score=382, Expect=2e-129]} {Mouse: ENSMUSG00000021190, Lgmn, legumain, [RH, Score=388, Expect=4e-132]} {Dmel: FBgn0023545, PIG-K, Phosphatidylinositol glycan anchor biosynthesis class K, [Score=127, Expect=1e-32]} {Celegans: WBGene00012144, T28H10.3, [RH, Score=327, Expect=7e-108]} {Smed: dd_Smed_v6_6456_0_1, dd_Smed_v6_6456_0_1, [Score=105, Expect=3e-25]} {RNA1509_312} {RNA1310_13933, RNA1509_312} {RNA1509_312, RNA815_6243.1}
22. MligTC455_40312 3856 80.34 Mlig455_008661, Mlig455_008672

Neo: -

Age: Down-Up-Up

Region-enriched R3: 2.080/0.00320

CYP2J2 4.564 0.898 0.755 - 0.977 0.973 0.961

Mlig455_008661 {REF} {Length: 2369} {Pfam: Cytochrome P450 [PF00067.24, score=340.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=298, Expect=3e-95]} {Mouse: ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=2e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=276, Expect=1e-86]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=3e-86]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=274, Expect=6e-86]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=4e-85]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=2e-84]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=270, Expect=2e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=269, Expect=6e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=2e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=5e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=219, Expect=9e-65]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=262, Expect=1e-81]} {RNA1509_32472, RNA1509_3430} {RNA1310_10280, RNA1509_32472, RNA1509_3430} {RNA1509_32472, RNA1509_3430, RNA815_4805}

Mlig455_008672 {REF} {Length: 2348} {Pfam: Cytochrome P450 [PF00067.24, score=341.0]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=298, Expect=3e-95]} {Mouse: ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=2e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=276, Expect=1e-86]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=2e-86]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=274, Expect=5e-86]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=4e-85]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=2e-84]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=269, Expect=6e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=269, Expect=7e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=3e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=6e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=219, Expect=7e-65]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=248, Expect=3e-76]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=261, Expect=3e-81]} {RNA1509_32472} {RNA1310_10280} {RNA815_4805}
23. MligTC455_18651 2559 53.32 Mlig455_067661

Neo: -

Age: -

Region-enriched R3: 1.583/0.04334

4.537 0.821 0.871 - 0.968 0.915 0.962 Mlig455_067661 {REF} {Length: 616} {RNA1509_2812} {RNA1310_3353.1, RNA1509_2812} {RNA1509_2812, RNA815_7653}
24. MligTC455_44102 5169 107.69 Mlig455_011991

Neo: -

Age: logFC(26M/2M)=0.278

Region-enriched R3: 1.948/0.00360
Region-enriched R4: 1.688/0.02863

HPGDS 4.533 0.917 - 0.865 0.941 0.846 0.964 Mlig455_011991 {REF} {Length: 1746} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=43.5]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=42.8]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=22.6]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=20.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=19.1]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [Score=67.8, Expect=2e-13]} {Mouse: ENSMUSG00000025934, Gsta3, glutathione S-transferase, alpha 3, [Score=62.4, Expect=1e-11]; ENSMUSG00000032348, Gsta4, glutathione S-transferase, alpha 4, [Score=60.5, Expect=6e-11]; ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [Score=60.5, Expect=5e-11]} {Celegans: WBGene00001756, gst-8, Probable glutathione S-transferase 8, [Score=84.0, Expect=5e-20]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=115, Expect=4e-32]} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1310_14959.1, RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359, RNA815_7403}
25. MligTC455_19081 4663 97.14 Mlig455_033359

Neo: -

Age: logFC(26M/2M)=0.367

Region-enriched R3: 1.666/0.00494
Region-enriched R5: 1.231/0.02896

4.518 0.762 0.911 - 0.953 0.946 0.946 Mlig455_033359 {REF} {Length: 508} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_1334} {RNA1310_80532} {RNA815_20560.2}
26. MligTC455_35217 5138 107.05 Mlig455_014282, Mlig455_014335

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.399

Region-enriched R3: 1.348/0.01129

4.508 0.875 0.891 - 0.923 0.862 0.957

Mlig455_014282 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=158.0]} {RNA1509_22501, RNA1509_4768} {RNA1310_7742.1, RNA1509_22501} {RNA1509_22501, RNA815_6411}

Mlig455_014335 {REF} {Length: 1769} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=159.5]} {RNA1509_4768} {RNA1310_7742.1} {RNA815_6411}
27. MligTC455_37239 1846 38.46 Mlig455_060082

Neo: -

Age: -

Region-enriched R3: 1.562/0.04763
Region-enriched R5: 1.292/0.04648

PANK4 4.494 0.829 0.857 - 0.958 0.883 0.967 Mlig455_060082 {REF} {Length: 1532} {Pfam: Fumble [PF03630.16, score=120.5]} {Human: ENSG00000273494, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]; ENSG00000157881, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=97.4, Expect=1e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=66.2, Expect=7e-12]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=170, Expect=1e-49]} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1310_20224, RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233, RNA815_7673}
28. MligTC455_52436 4103 85.47 Mlig455_036594, Mlig455_057758

Neo: -

Age: -

Region-enriched R3: 2.299/0.00029

FMO4 4.489 0.805 0.857 - 0.939 0.921 0.967

Mlig455_036594 {REF} {Length: 1772} {TRANSSPLICED} {Pfam: Flavin-binding monooxygenase-like [PF00743.21, score=121.5]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=43.8]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=21.1]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=18.3]} {Human: ENSG00000076258, FMO4, flavin containing monooxygenase 4, [Score=104, Expect=1e-23]} {Mouse: ENSMUSG00000026560, Fmo9, flavin containing monooxygenase 9, [Score=102, Expect=5e-23]; ENSMUSG00000028088, Fmo5, flavin containing monooxygenase 5, [Score=102, Expect=3e-23]} {Dmel: FBgn0033079, Fmo-2, Flavin-containing monooxygenase 2, [Score=132, Expect=3e-34]} {Celegans: WBGene00016728, C46H11.2, Flavin-containing monooxygenase, [Score=108, Expect=1e-25]} {Smed: dd_Smed_v6_9449_0_1, dd_Smed_v6_9449_0_1, [Score=93.2, Expect=1e-20]} {RNA1509_13926} {RNA1310_13123.1} {RNA815_5157.1}

Mlig455_057758 {REF} {Length: 1759} {TRANSSPLICED} {Pfam: Flavin-binding monooxygenase-like [PF00743.21, score=125.0]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=49.5]; FAD-NAD(P)-binding [PF13454.8, score=29.2]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=28.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=27.1]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=19.0]; FAD dependent oxidoreductase [PF01266.26, score=18.3]} {Human: ENSG00000076258, FMO4, flavin containing monooxygenase 4, [Score=111, Expect=1e-25]} {Mouse: ENSMUSG00000028088, Fmo5, flavin containing monooxygenase 5, [Score=113, Expect=2e-26]; ENSMUSG00000026560, Fmo9, flavin containing monooxygenase 9, [Score=108, Expect=6e-25]} {Dmel: FBgn0033079, Fmo-2, Flavin-containing monooxygenase 2, [Score=148, Expect=1e-39]} {Celegans: WBGene00016728, C46H11.2, Flavin-containing monooxygenase, [Score=108, Expect=9e-26]} {Smed: dd_Smed_v6_9449_0_1, dd_Smed_v6_9449_0_1, [Score=106, Expect=6e-25]} {RNA1509_13926} {RNA1310_13123.1} {RNA815_5157.1}
29. MligTC455_18723 1597 33.27 Mlig455_004384

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.781

Region-enriched R3: 2.164/0.00079
Region-enriched R4: 1.576/0.04930
Region-enriched R5: 1.329/0.03977

SLC3A1 4.477 0.787 0.884 - 0.927 0.911 0.968 Mlig455_004384 {REF} {Length: 2040} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=310.6]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=371, Expect=2e-119]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=372, Expect=4e-120]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=384, Expect=2e-126]} {Celegans: WBGene00000224, atgp-1, Amino acid Transporter GlycoProtein subunit, [RH, Score=146, Expect=3e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=8e-12]} {RNA1509_19345} {RNA1310_12682.1} {RNA815_15968}
30. MligTC455_18724 1612 33.59 Mlig455_037198

Neo: -

Age: -

Region-enriched R3: 2.022/0.00141

SLC3A1 4.471 0.786 0.883 - 0.924 0.909 0.969 Mlig455_037198 {REF} {Length: 2052} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=311.9]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=373, Expect=2e-120]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=374, Expect=5e-121]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=385, Expect=1e-126]} {Celegans: WBGene00000225, atgp-2, Amino acid Transporter GlycoProtein subunit, [RH, Score=147, Expect=2e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=9e-12]} {RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1310_12682.1, RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1509_14094, RNA1509_15182, RNA1509_19345, RNA815_15968}
31. MligTC455_16062 635 13.22 Mlig455_026314

Neo: -

Age: logFC(26M/2M)=-0.923

Region-enriched R3: 2.095/0.00000
Region-enriched R4: 1.472/0.00808

SLC39A14 4.446 0.773 0.879 - 0.943 0.883 0.968 Mlig455_026314 {REF} {Length: 5567} {Pfam: ZIP Zinc transporter [PF02535.24, score=127.9]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=138, Expect=1e-36]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=135, Expect=5e-36]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=95.5, Expect=1e-21]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=114, Expect=8e-29]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=162, Expect=2e-46]} {RNA1509_16476} {RNA1310_12919} {RNA815_5274}
32. MligTC455_20725 2475 51.57 Mlig455_035227

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.822

Region-enriched R3: 2.240/0.00003

SLC1A6 4.437 0.907 0.872 0.863 0.959 0.836 - Mlig455_035227 {REF} {Length: 2154} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=422.3]} {Human: ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [RH, Score=462, Expect=2e-157]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=456, Expect=3e-156]; ENSMUSG00000005357, Slc1a6, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, [RH, Score=452, Expect=1e-153]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=373, Expect=3e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=422, Expect=3e-143]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=422, Expect=8e-144]} {RNA1509_7401} {RNA1310_8553.1, RNA1509_7401} {RNA1509_7401, RNA815_2974.1}
33. MligTC455_49659 4741 98.77 Mlig455_011512, Mlig455_050003

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.314

Region-enriched R3: 1.923/0.00380

4.429 0.865 0.800 - 0.951 0.850 0.963

Mlig455_011512 {REF} {Length: 2299} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}

Mlig455_050003 {REF} {Length: 1812} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}
34. MligTC455_18868 1328 27.67 Mlig455_067483

Neo: -

Age: -

Region-enriched R3: 1.928/0.00492
Region-enriched R4: 1.837/0.01691
Region-enriched R5: 1.462/0.02245

4.426 0.830 - 0.864 0.950 0.817 0.965 Mlig455_067483 {REF} {Length: 405} {RNA1509_5037} {RNA1310_19379} {RNA815_6182.1}
35. MligTC455_35632 6861 142.93 Mlig455_047206

Neo: -

Age: -

Region-enriched R3: 1.984/0.00032
Region-enriched R4: 1.605/0.01274
Region-enriched R5: 1.441/0.00908

DHDH 4.42 - 0.783 0.909 0.836 0.954 0.938 Mlig455_047206 {REF} {Length: 1483} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=86.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=245, Expect=8e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=247, Expect=1e-79]} {Dmel: FBgn0031418, CG3609, [Score=229, Expect=5e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=211, Expect=2e-66]} {RNA1509_4889} {RNA1310_24236} {RNA815_11111.1}
36. MligTC455_18869 1346 28.04 Mlig455_067491

Neo: -

Age: -

Region-enriched R3: 1.933/0.00397
Region-enriched R4: 1.775/0.01938
Region-enriched R5: 1.440/0.02287

4.408 0.828 - 0.862 0.952 0.797 0.969 Mlig455_067491 {REF} {Length: 2320} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=72.5]; GDP-mannose 4,6 dehydratase [PF16363.7, score=51.3]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=46.4]; Male sterility protein [PF07993.14, score=42.2]; NAD(P)H-binding [PF13460.8, score=39.3]; Polysaccharide biosynthesis protein [PF02719.17, score=30.0]; KR domain [PF08659.12, score=29.5]; NmrA-like family [PF05368.15, score=28.0]; short chain dehydrogenase [PF00106.27, score=19.3]} {Celegans: WBGene00017429, F13D11.4, [RH, Score=213, Expect=4e-66]} {RNA1509_20033, RNA1509_5037} {RNA1310_19379, RNA1509_20033, RNA1509_5037} {RNA1509_20033, RNA1509_5037, RNA815_6182.1}
37. MligTC455_52041 2170 45.21 Mlig455_029621

Neo: -

Age: logFC(26M/2M)=0.515

Region-enriched R3: 1.780/0.00221
Region-enriched R5: 1.483/0.00437

SCIN 4.401 0.741 0.833 - 0.962 0.904 0.961 Mlig455_029621 {REF} {Length: 1419} {Pfam: Gelsolin repeat [PF00626.24, score=61.4]} {Human: ENSG00000006747, SCIN, scinderin, [Score=78.6, Expect=3e-15]} {Mouse: ENSMUSG00000002565, Scin, scinderin, [Score=82.8, Expect=7e-17]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=76.6, Expect=7e-15]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [Score=214, Expect=8e-67]} {RNA1509_17911} {RNA1310_15610} {RNA815_7841}
38. MligTC455_52040 2198 45.8 Mlig455_029597

Neo: Germline

Age: logFC(26M/2M)=0.256

Region-enriched R3: 1.723/0.00072
Region-enriched R5: 1.481/0.00114

VIL1 4.398 0.741 0.831 - 0.962 0.907 0.957 Mlig455_029597 {REF} {Length: 2577} {Pfam: Gelsolin repeat [PF00626.24, score=113.7]} {Human: ENSG00000127831, VIL1, villin 1, [Score=182, Expect=5e-53]; ENSG00000148180, GSN, gelsolin, [Score=179, Expect=1e-49]; ENSG00000135407, AVIL, advillin, [Score=174, Expect=1e-47]} {Mouse: ENSMUSG00000026879, Gsn, gelsolin, [Score=185, Expect=7e-52]; ENSMUSG00000026175, Vil1, villin 1, [Score=182, Expect=1e-50]} {Dmel: FBgn0010225, Gel, Gelsolin, [Score=194, Expect=3e-55]} {Celegans: WBGene00010593, gsnl-1, Gelsolin-like protein 1, [Score=164, Expect=4e-46]} {Smed: dd_Smed_v6_1215_0_1, dd_Smed_v6_1215_0_1, [RH, Score=403, Expect=3e-140]} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1310_15610, RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633} {RNA1509_12411, RNA1509_17911, RNA1509_2858, RNA1509_30271, RNA1509_44412, RNA1509_44633, RNA815_7841}
39. MligTC455_19080 969 20.19 Mlig455_033341

Neo: -

Age: Up-Down-Down

Region-enriched R5: 1.378/0.02877

4.397 0.781 0.860 - 0.958 0.851 0.947 Mlig455_033341 {REF} {Length: 1009} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_41133} {RNA1310_2059.1} {RNA815_20560.2}
40. MligTC455_18925 1222 25.47 Mlig455_034430

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.749/0.00485

RGS12 4.366 0.872 0.849 - 0.958 0.717 0.970 Mlig455_034430 {REF} {Length: 1569} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=98.3]} {Human: ENSG00000159788, RGS12, regulator of G protein signaling 12, [Score=112, Expect=3e-26]; ENSG00000169220, RGS14, regulator of G protein signaling 14, [Score=110, Expect=6e-26]} {Mouse: ENSMUSG00000052087, Rgs14, regulator of G-protein signaling 14, [RH, Score=114, Expect=2e-27]} {Dmel: FBgn0020278, loco, locomotion defects, [Score=99.4, Expect=3e-22]} {Celegans: WBGene00004347, rgs-4, Regulator of G protein Signaling, [Score=82.8, Expect=3e-18]} {Smed: dd_Smed_v6_3873_0_1, dd_Smed_v6_3873_0_1, [Score=95.5, Expect=3e-23]} {RNA1509_7258} {RNA1310_21231} {RNA815_8874}
41. MligTC455_53879 3408 71 Mlig455_056363

Neo: -

Age: logFC(26M/2M)=0.278

Region-enriched R3: 1.852/0.00001

CLCA1 4.365 0.894 0.803 0.791 - 0.919 0.958 Mlig455_056363 {REF} {Length: 3111} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=167.5]; von Willebrand factor type A domain [PF00092.30, score=46.2]; von Willebrand factor type A domain [PF13519.8, score=42.1]; von Willebrand factor type A domain [PF13768.8, score=37.2]; VWA domain containing CoxE-like protein [PF05762.16, score=23.6]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [RH, Score=265, Expect=9e-75]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [RH, Score=273, Expect=6e-78]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [RH, Score=178, Expect=5e-46]} {RNA1509_656} {RNA1310_5461.1} {RNA815_1665}
42. MligTC455_36240 5999 124.98 Mlig455_043113

Neo: -

Age: logFC(26M/2M)=0.402

EPHX4 4.343 0.842 0.738 - 0.839 0.970 0.954 Mlig455_043113 {REF} {Length: 2152} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=86.1]; Alpha/beta hydrolase family [PF12697.9, score=72.2]; Serine aminopeptidase, S33 [PF12146.10, score=55.9]; Ndr family [PF03096.16, score=20.5]} {Human: ENSG00000172031, EPHX4, epoxide hydrolase 4, [RH, Score=248, Expect=1e-78]} {Mouse: ENSMUSG00000033805, Ephx4, epoxide hydrolase 4, [RH, Score=237, Expect=1e-74]} {Dmel: FBgn0035951, CG5068, [Score=49.7, Expect=3e-06]} {Celegans: WBGene00019329, ceeh-1, Epoxide hydrolase 1, [RH, Score=228, Expect=1e-70]} {Smed: dd_Smed_v6_2011_0_1, dd_Smed_v6_2011_0_1, [RH, Score=252, Expect=8e-81]} {RNA1509_19687, RNA1509_20879, RNA1509_7823} {RNA1310_15717.1, RNA1509_19687, RNA1509_20879} {RNA1509_19687, RNA1509_20879, RNA815_5437.1}
43. MligTC455_43406 1382 28.79 Mlig455_063546

Neo: -

Age: logFC(26M/2M)=-0.363

Region-enriched R4: 1.356/0.01589
Region-enriched R3: 1.139/0.04629

TRPA1 4.338 - 0.844 0.758 0.956 0.917 0.863 Mlig455_063546 {REF} {Length: 5889} {Pfam: Ion transport protein [PF00520.33, score=52.1]; Ankyrin repeat [PF00023.32, score=19.5]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=130, Expect=7e-30]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=127, Expect=5e-29]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=139, Expect=6e-33]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=153, Expect=2e-37]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [Score=132, Expect=7e-31]} {RNA1509_21433, RNA1509_40381, RNA1509_43070, RNA1509_46763} {RNA1310_1768.1, RNA1509_21433, RNA1509_40381, RNA1509_43070} {RNA1509_21433, RNA1509_40381, RNA1509_43070, RNA815_3153}
44. MligTC455_16063 772 16.08 Mlig455_026358, Mlig455_052707

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.372

Region-enriched R3: 2.027/0.00000
Region-enriched R4: 1.354/0.01177

SLC39A14 4.337 0.763 0.794 - 0.946 0.871 0.963

Mlig455_026358 {REF} {Length: 2562} {Pfam: ZIP Zinc transporter [PF02535.24, score=177.7]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=187, Expect=4e-53]; ENSG00000196950, SLC39A10, solute carrier family 39 member 10, [Score=179, Expect=3e-48]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=185, Expect=3e-52]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=144, Expect=5e-37]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=161, Expect=3e-44]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=213, Expect=2e-63]} {RNA1509_35963, RNA1509_39667} {RNA1310_11294, RNA1509_39667} {RNA1509_39667, RNA815_5274}

Mlig455_052707 {REF} {Length: 2641} {Pfam: ZIP Zinc transporter [PF02535.24, score=177.7]} {Human: ENSG00000104635, SLC39A14, solute carrier family 39 member 14, [Score=187, Expect=4e-53]; ENSG00000196950, SLC39A10, solute carrier family 39 member 10, [Score=179, Expect=3e-48]} {Mouse: ENSMUSG00000022094, Slc39a14, solute carrier family 39 (zinc transporter), member 14, [Score=185, Expect=3e-52]} {Dmel: FBgn0036461, Zip71B, Zinc/iron regulated transporter-related protein 71B, [Score=144, Expect=5e-37]} {Celegans: WBGene00021936, zipt-20, Zrt (ZRT), Irt-(IRT-) like Protein Transporter, [Score=161, Expect=3e-44]} {Smed: dd_Smed_v6_8605_0_1, dd_Smed_v6_8605_0_1, [Score=213, Expect=2e-63]} {RNA1509_35963, RNA1509_50293} {RNA1310_11294, RNA1509_35963, RNA1509_50293} {RNA1509_35963, RNA1509_50293, RNA815_5274}
45. MligTC455_36239 5931 123.57 Mlig455_043102

Neo: -

Age: logFC(26M/2M)=0.673

EPHX4 4.324 0.840 0.736 - 0.838 0.967 0.943 Mlig455_043102 {REF} {Length: 1398} {Human: ENSG00000172031, EPHX4, epoxide hydrolase 4, [Score=120, Expect=5e-32]} {Mouse: ENSMUSG00000033805, Ephx4, epoxide hydrolase 4, [Score=107, Expect=2e-27]} {Celegans: WBGene00019329, ceeh-1, Epoxide hydrolase 1, [Score=103, Expect=5e-26]} {Smed: dd_Smed_v6_2011_0_1, dd_Smed_v6_2011_0_1, [Score=131, Expect=8e-37]} {RNA1509_7823} {RNA1310_15717.2} {RNA815_5437.1}
46. MligTC455_48071 1712 35.67 Mlig455_048082

Neo: -

Age: logFC(26M/2M)=-0.321

Region-enriched R4: 1.489/0.04451

HSD11B1 4.31 0.804 0.762 - 0.921 0.858 0.965 Mlig455_048082 {REF} {Length: 1293} {Pfam: short chain dehydrogenase [PF00106.27, score=123.3]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=75.2]; KR domain [PF08659.12, score=26.1]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=155, Expect=4e-45]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=150, Expect=1e-43]} {Dmel: FBgn0027583, CG7601, [Score=82.4, Expect=9e-18]} {Celegans: WBGene00000982, dhs-19, DeHydrogenases, Short chain, [Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_4976_0_1, dd_Smed_v6_4976_0_1, [Score=62.8, Expect=3e-11]} {RNA1509_14549, RNA1509_28912} {RNA1310_26648, RNA1509_14549, RNA1509_28912} {RNA1509_14549, RNA1509_28912, RNA815_11342}
47. MligTC455_36347 2542 52.97 Mlig455_027675

Neo: -

Age: -

ACP7 4.294 0.816 - 0.762 0.893 0.869 0.954 Mlig455_027675 {REF} {Length: 2194} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=89.6]; Iron/zinc purple acid phosphatase-like protein C [PF14008.8, score=79.5]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=75.2]; PhoD-like phosphatase [PF09423.12, score=19.2]} {Human: ENSG00000183760, ACP7, acid phosphatase 7, tartrate resistant (putative), [RH, Score=431, Expect=2e-148]} {Mouse: ENSMUSG00000037469, Acp7, acid phosphatase 7, tartrate resistant, [RH, Score=448, Expect=1e-154]} {Dmel: FBgn0030245, CG1637, [RH, Score=434, Expect=9e-150]} {Celegans: WBGene00219316, F21A3.11, Purple acid phosphatase, [RH, Score=406, Expect=2e-138]} {Smed: dd_Smed_v6_1053_0_1, dd_Smed_v6_1053_0_1, [RH, Score=537, Expect=0.0]} {RNA1509_2158} {RNA1310_12511.1, RNA1509_2158} {RNA1509_2158, RNA815_6230.1}
48. MligTC455_29886 979 20.4 Mlig455_029016

Neo: -

Age: logFC(26M/2M)=-0.339

Region-enriched R3: 1.707/0.00111

4.281 0.826 0.880 - 0.736 0.878 0.961 Mlig455_029016 {REF} {Length: 2165} {TRANSSPLICED} {Pfam: Innexin [PF00876.20, score=364.0]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=121, Expect=1e-30]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=304, Expect=3e-100]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=305, Expect=3e-100]} {RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541} {RNA1310_23805, RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541} {RNA1509_19970, RNA1509_32682, RNA1509_39326, RNA1509_47177, RNA1509_50541, RNA815_9290}
49. MligTC455_24859 5590 116.45 Mlig455_054066, Mlig455_063284

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.306

Region-enriched R3: 2.202/0.00434

4.26 0.879 0.798 - 0.790 0.841 0.952

Mlig455_054066 {REF} {Length: 1406} {RNA1509_33411, RNA1509_7753} {RNA1310_22791, RNA1509_33411} {RNA1509_33411, RNA815_10514.1}

Mlig455_063284 {REF} {Length: 1414} {Pfam: Multi-glycosylated core protein 24 (MGC-24), sialomucin [PF05283.13, score=46.5]} {Mouse: ENSMUSG00000050912, Tmem123, transmembrane protein 123, [Score=46.6, Expect=2e-06]} {Dmel: FBgn0045823, vsg, visgun, [Score=53.1, Expect=8e-09]} {Smed: dd_Smed_v6_828_0_1, dd_Smed_v6_828_0_1, [RH, Score=53.5, Expect=2e-10]} {RNA1509_7753} {RNA1310_22791} {RNA815_10514.1}
50. MligTC455_18679 3022 62.97 Mlig455_060923, Mlig455_060989

Neo: -

Age: logFC(26M/2M)=0.845

Region-enriched R3: 2.119/0.00016

LITAF 4.256 0.776 0.762 0.797 0.976 - 0.945

Mlig455_060923 {REF} {Length: 783} {Pfam: LITAF-like zinc ribbon domain [PF10601.11, score=82.6]} {Human: ENSG00000189067, LITAF, lipopolysaccharide induced TNF factor, [RH, Score=95.9, Expect=1e-25]} {Mouse: ENSMUSG00000022500, Litaf, LPS-induced TN factor, [Score=95.9, Expect=6e-26]} {Dmel: FBgn0052280, CG32280, [Score=77.4, Expect=5e-19]} {Celegans: WBGene00009484, F36G3.3, [Score=82.4, Expect=5e-21]} {Smed: dd_Smed_v6_353_0_1, dd_Smed_v6_353_0_1, [Score=85.9, Expect=1e-22]} {RNA1509_6172} {RNA1310_40991.2} {RNA815_19869}

Mlig455_060989 {REF} {Length: 1766} {Pfam: LITAF-like zinc ribbon domain [PF10601.11, score=83.0]} {Human: ENSG00000189067, LITAF, lipopolysaccharide induced TNF factor, [RH, Score=98.2, Expect=1e-26]} {Mouse: ENSMUSG00000022500, Litaf, LPS-induced TN factor, [Score=96.3, Expect=4e-26]} {Dmel: FBgn0052280, CG32280, [Score=77.0, Expect=3e-19]} {Celegans: WBGene00009484, F36G3.3, [Score=75.9, Expect=1e-18]} {Smed: dd_Smed_v6_353_0_1, dd_Smed_v6_353_0_1, [Score=84.0, Expect=5e-22]} {RNA1509_6172} {RNA1310_92258} {RNA815_19869}
51. MligTC455_47633 2997 62.43 Mlig455_021264, Mlig455_021535

Neo: -

Age: -

Region-enriched R4: 1.984/0.00494
Region-enriched R3: 1.676/0.01623

4.241 0.858 0.739 0.757 0.960 - 0.927

Mlig455_021264 {REF} {Length: 1079} {Pfam: Universal stress protein family [PF00582.28, score=103.9]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=130, Expect=1e-39]} {RNA1509_6559} {RNA1310_39993} {RNA815_18311}

Mlig455_021535 {REF} {Length: 938} {Pfam: Universal stress protein family [PF00582.28, score=103.9]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=130, Expect=1e-39]} {RNA1509_6559} {RNA1310_39993} {RNA815_18311}
52. MligTC455_20726 1772 36.91 Mlig455_035274

Neo: -

Age: -

Region-enriched R3: 2.119/0.00009

SLC1A6 4.233 0.889 0.747 0.796 0.953 0.848 - Mlig455_035274 {REF} {Length: 2086} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=422.3]} {Human: ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [RH, Score=462, Expect=9e-158]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=457, Expect=3e-156]; ENSMUSG00000005357, Slc1a6, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6, [RH, Score=452, Expect=6e-154]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=373, Expect=4e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=421, Expect=6e-143]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=427, Expect=2e-145]} {RNA1509_5272, RNA1509_57758, RNA1509_7401} {RNA1310_8553.1, RNA1509_5272, RNA1509_57758} {RNA1509_5272, RNA1509_57758, RNA815_2974.1}
53. MligTC455_45315 4773 99.43 Mlig455_037736

Neo: -

Age: -

4.21 - 0.730 0.791 0.808 0.925 0.956 Mlig455_037736 {REF} {Length: 2269} {RNA1509_18494, RNA1509_5801} {RNA1310_12524.1, RNA1509_5801} {RNA1509_5801, RNA815_3944.1}
54. MligTC455_42353 5099 106.23 Mlig455_014274, Mlig455_014309, Mlig455_018673

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.786

Region-enriched R3: 2.226/0.00003

AC113554.1, ACE 4.209 0.809 0.712 - 0.930 0.795 0.963

Mlig455_014274 {REF} {Length: 2949} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_37062, RNA1509_441} {RNA1310_8949, RNA1509_37062} {RNA1509_37062, RNA815_4061}

Mlig455_014309 {REF} {Length: 2926} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441} {RNA1310_8949} {RNA815_4061}

Mlig455_018673 {REF} {Length: 833} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=122.4]} {Human: ENSG00000264813, AC113554.1, novel transcript, [Score=103, Expect=3e-24]; ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=103, Expect=2e-24]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=97.8, Expect=2e-22]; ENSMUSG00000101605, Ace3, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, [Score=93.2, Expect=6e-21]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [Score=74.7, Expect=7e-15]} {Smed: dd_Smed_v6_13804_0_1, dd_Smed_v6_13804_0_1, [Score=51.2, Expect=2e-07]} {RNA1509_16360} {RNA1310_8949} {RNA815_4061}
55. MligTC455_41283 1026 21.38 Mlig455_056291

Neo: -

Age: Down-Up-Up

Region-enriched R3: 2.480/0.00000
Region-enriched R4: 1.642/0.01172
Region-enriched R5: 1.330/0.01324

4.207 0.786 0.766 0.874 0.830 - 0.951 Mlig455_056291 {REF} {Length: 1075} {RNA1509_3034} {RNA1310_55537, RNA1509_3034} {RNA1509_3034, RNA815_28451}
56. MligTC455_20464 3164 65.93 Mlig455_036496, Mlig455_056384

Neo: -

Age: -

Region-enriched R3: 1.967/0.00269
Region-enriched R4: 1.871/0.00861

RAB35 4.174 0.795 0.778 - 0.972 0.750 0.879

Mlig455_036496 {REF} {Length: 1520} {Pfam: Ras family [PF00071.24, score=127.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=89.3]; ADP-ribosylation factor family [PF00025.23, score=49.9]; RsgA GTPase [PF03193.18, score=37.9]; 50S ribosome-binding GTPase [PF01926.25, score=24.4]; Signal recognition particle receptor beta subunit [PF09439.12, score=20.9]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.1]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [Score=110, Expect=2e-29]; ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=105, Expect=9e-28]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [Score=110, Expect=1e-29]; ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=106, Expect=5e-28]} {Dmel: FBgn0031090, Rab35, [Score=118, Expect=8e-33]} {Celegans: WBGene00004277, rab-18, Ras-related protein Rab-18, [Score=125, Expect=8e-36]} {Smed: dd_Smed_v6_2603_0_1, dd_Smed_v6_2603_0_1, [RH, Score=146, Expect=4e-44]} {RNA1509_21258} {RNA1310_21310.1} {RNA815_8782.1}

Mlig455_056384 {REF} {Length: 1510} {Pfam: Ras family [PF00071.24, score=127.4]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=89.3]; ADP-ribosylation factor family [PF00025.23, score=51.7]; RsgA GTPase [PF03193.18, score=37.8]; 50S ribosome-binding GTPase [PF01926.25, score=24.4]; Signal recognition particle receptor beta subunit [PF09439.12, score=21.0]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.6]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [Score=110, Expect=2e-29]; ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=105, Expect=9e-28]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [Score=110, Expect=1e-29]; ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=106, Expect=4e-28]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=105, Expect=2e-27]} {Dmel: FBgn0031090, Rab35, [Score=118, Expect=6e-33]} {Celegans: WBGene00004277, rab-18, Ras-related protein Rab-18, [Score=125, Expect=7e-36]} {Smed: dd_Smed_v6_2603_0_1, dd_Smed_v6_2603_0_1, [RH, Score=147, Expect=4e-44]} {RNA1509_12602, RNA1509_21258} {RNA1310_21310.1, RNA1509_12602, RNA1509_21258} {RNA1509_12602, RNA1509_21258, RNA815_8782.1}
57. MligTC455_33577 18072 376.49 Mlig455_043957, Mlig455_043969, Mlig455_044039

Neo: -

Age: logFC(26M/2M)=0.423

Region-enriched R5: 1.425/0.00134
Region-enriched R4: 1.282/0.02044

IDH1 4.144 0.806 0.769 - 0.739 0.967 0.863

Mlig455_043957 {REF} {Length: 2414} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=266.7]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=664, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=660, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=636, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=651, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=652, Expect=0.0]} {RNA1509_16912} {RNA1310_10691.1, RNA1509_16912} {RNA1509_16912, RNA815_3934}

Mlig455_043969 {REF} {Length: 2413} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=267.0]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=667, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=639, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=654, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=655, Expect=0.0]} {RNA1509_16912, RNA1509_26642, RNA1509_847} {RNA1310_10691.1, RNA1509_26642, RNA1509_847} {RNA1509_26642, RNA1509_847, RNA815_3934}

Mlig455_044039 {REF} {Length: 2905} {Pfam: Isocitrate/isopropylmalate dehydrogenase [PF00180.22, score=267.0]} {Human: ENSG00000138413, IDH1, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, [RH, Score=667, Expect=0.0]} {Mouse: ENSMUSG00000025950, Idh1, isocitrate dehydrogenase 1 (NADP+), soluble, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0001248, Idh, Isocitrate dehydrogenase, [RH, Score=639, Expect=0.0]} {Celegans: WBGene00010317, idh-1, Isocitrate dehydrogenase [NADP], [RH, Score=654, Expect=0.0]} {Smed: dd_Smed_v6_3770_0_1, dd_Smed_v6_3770_0_1, [RH, Score=655, Expect=0.0]} {RNA1509_16912, RNA1509_38467} {RNA1310_10691.1, RNA1509_38467} {RNA1509_38467, RNA815_3934}
58. MligTC455_22151 1286 26.78 Mlig455_054961

Neo: -

Age: Down-Up-Down

Region-enriched R4: 2.174/0.00000
Region-enriched R3: 1.898/0.00000
Region-enriched R5: 1.123/0.00549

XDH 4.132 0.721 - 0.745 0.921 0.792 0.953 Mlig455_054961 {REF} {Length: 8931} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=746.5]; [2Fe-2S] binding domain [PF01799.22, score=187.9]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=151.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=115.0]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=110.3]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=28.4]} {Human: ENSG00000158125, XDH, xanthine dehydrogenase, [Score=490, Expect=1e-144]; ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=472, Expect=2e-138]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=496, Expect=5e-147]; ENSMUSG00000038242, Aox4, aldehyde oxidase 4, [Score=472, Expect=7e-139]} {Dmel: FBgn0038349, AOX3, Aldehyde oxidase 3, [RH, Score=658, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=501, Expect=1e-148]} {RNA1509_48253} {RNA1310_3150.1} {RNA815_224.3}
59. MligTC455_34688 756 15.75 Mlig455_049905

Neo: -

Age: logFC(26M/2M)=0.524

Region-enriched R3: 2.234/0.00031
Region-enriched R4: 1.743/0.02090
Region-enriched R5: 1.276/0.04216

MGAM2 4.13 - 0.756 0.739 0.923 0.750 0.962 Mlig455_049905 {REF} {Length: 4307} {Pfam: Glycosyl hydrolases family 31 [PF01055.28, score=486.1]; N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase [PF16863.7, score=39.1]; Galactose mutarotase-like [PF13802.8, score=25.5]} {Human: ENSG00000257743, MGAM2, maltase-glucoamylase 2 (putative), [Score=632, Expect=0.0]; ENSG00000278563, MGAM2, maltase-glucoamylase 2 (putative), [Score=632, Expect=0.0]; ENSG00000257335, MGAM, maltase-glucoamylase, [Score=626, Expect=0.0]; ENSG00000282607, MGAM, maltase-glucoamylase, [Score=617, Expect=0.0]; ENSG00000090402, SI, sucrase-isomaltase, [Score=605, Expect=0.0]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [Score=644, Expect=0.0]; ENSMUSG00000027790, Sis, sucrase isomaltase (alpha-glucosidase), [Score=631, Expect=0.0]} {Dmel: FBgn0027588, GCS2alpha, Glucosidase 2 alpha subunit, [Score=226, Expect=1e-61]} {Celegans: WBGene00017071, aagr-1, Acid Alpha Glucosidase Relate, [RH, Score=476, Expect=5e-153]} {Smed: dd_Smed_v6_1062_0_1, dd_Smed_v6_1062_0_1, [Score=530, Expect=2e-174]} {RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412} {RNA1310_4558.1, RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412} {RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412, RNA815_1348}
60. MligTC455_30314 17741 369.6 Mlig455_014122, Mlig455_014131

Neo: -

Age: -

Region-enriched R3: 1.904/0.00059

TUBB4B 4.127 0.876 - 0.750 0.971 0.815 0.715

Mlig455_014122 {REF} {Length: 2342} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=235.9]; Tubulin C-terminal domain [PF03953.19, score=141.7]; Misato Segment II tubulin-like domain [PF10644.11, score=24.4]} {Human: ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [RH, Score=913, Expect=0.0]} {Mouse: ENSMUSG00000036752, Tubb4b, tubulin, beta 4B class IVB, [RH, Score=913, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [RH, Score=854, Expect=0.0]} {Celegans: WBGene00006538, tbb-4, Tubulin beta-4 chain, [RH, Score=856, Expect=0.0]} {Smed: dd_Smed_v6_83_0_3, dd_Smed_v6_83_0_3, [RH, Score=910, Expect=0.0]} {RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269} {RNA1310_15130.1, RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269} {RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269, RNA815_1610.1}

Mlig455_014131 {REF} {Length: 2057} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=235.8]; Tubulin C-terminal domain [PF03953.19, score=143.3]; Misato Segment II tubulin-like domain [PF10644.11, score=24.4]} {Human: ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [RH, Score=913, Expect=0.0]} {Mouse: ENSMUSG00000036752, Tubb4b, tubulin, beta 4B class IVB, [RH, Score=913, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [RH, Score=854, Expect=0.0]} {Celegans: WBGene00006538, tbb-4, Tubulin beta-4 chain, [RH, Score=856, Expect=0.0]} {Smed: dd_Smed_v6_83_0_1, dd_Smed_v6_83_0_1, [RH, Score=910, Expect=0.0]} {RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735} {RNA1310_15130.1, RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735} {RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735, RNA815_1610.1}
61. MligTC455_50091 3389 70.6 Mlig455_041940

Neo: -

Age: logFC(26M/2M)=0.438

CAT 4.117 0.781 0.724 - 0.970 0.713 0.929 Mlig455_041940 {REF} {Length: 2013} {TRANSSPLICED} {Pfam: Catalase [PF00199.21, score=645.7]; Catalase-related immune-responsive [PF06628.14, score=80.3]} {Human: ENSG00000121691, CAT, catalase, [RH, Score=744, Expect=0.0]} {Mouse: ENSMUSG00000027187, Cat, catalase, [RH, Score=744, Expect=0.0]} {Dmel: FBgn0000261, Cat, Catalase, [RH, Score=704, Expect=0.0]} {Celegans: WBGene00000831, ctl-2, Peroxisomal catalase 1, [RH, Score=635, Expect=0.0]} {Smed: dd_Smed_v6_859_0_1, dd_Smed_v6_859_0_1, [RH, Score=640, Expect=0.0]} {RNA1509_2448, RNA1509_24848} {RNA1310_13356.1, RNA1509_2448, RNA1509_24848} {RNA1509_2448, RNA1509_24848, RNA815_4899.1}
62. MligTC455_46060 5515 114.89 Mlig455_020392, Mlig455_028391, Mlig455_028425, Mlig455_058436

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.963/0.00990
Region-enriched R4: 1.696/0.04858
Region-enriched R5: 1.424/0.04296

4.036 0.752 0.777 - 0.755 0.791 0.961

Mlig455_020392 {REF} {Length: 1388} {Pfam: Sleepless protein [PF17064.7, score=21.0]} {Smed: dd_Smed_v6_3595_0_1, dd_Smed_v6_3595_0_1, [RH, Score=44.7, Expect=2e-06]} {RNA1509_9885} {RNA1310_5794.1} {RNA815_1706}

Mlig455_028391 {REF} {Length: 1388} {Pfam: Sleepless protein [PF17064.7, score=21.0]} {Smed: dd_Smed_v6_3595_0_1, dd_Smed_v6_3595_0_1, [RH, Score=44.7, Expect=2e-06]} {RNA1509_9885} {RNA1310_5794.1} {RNA815_1706}

Mlig455_028425 {REF} {Length: 1390} {Pfam: Sleepless protein [PF17064.7, score=21.0]} {Smed: dd_Smed_v6_3595_0_1, dd_Smed_v6_3595_0_1, [RH, Score=44.7, Expect=2e-06]} {RNA1509_9885} {RNA1310_5794.1} {RNA815_1706}

Mlig455_058436 {REF} {Length: 1395} {Pfam: Sleepless protein [PF17064.7, score=21.0]} {Smed: dd_Smed_v6_3595_0_1, dd_Smed_v6_3595_0_1, [RH, Score=44.7, Expect=3e-06]} {RNA1509_8861, RNA1509_9885} {RNA1310_5794.1, RNA1509_8861, RNA1509_9885} {RNA1509_8861, RNA1509_9885, RNA815_1706}
63. MligTC455_38075 513 10.69 Mlig455_037147

Neo: -

Age: Down-Down-Up

4.003 0.732 0.710 - 0.822 0.787 0.952 Mlig455_037147 {REF} {Length: 3140} {Pfam: Zona pellucida-like domain [PF00100.25, score=46.9]; Scavenger receptor cysteine-rich domain [PF00530.20, score=43.8]} {RNA1509_39101} {RNA1310_14098} {RNA815_2224.1}
64. MligTC455_45090 767 15.97 Mlig455_050942

Neo: -

Age: Down-Up-Down

Region-enriched R3: 1.666/0.00039
Region-enriched R4: 1.435/0.01328

NAAA 3.981 0.722 - 0.716 0.970 0.780 0.793 Mlig455_050942 {REF} {Length: 1563} {Pfam: beta subunit of N-acylethanolamine-hydrolyzing acid amidase [PF15508.8, score=40.2]; Linear amide C-N hydrolases, choloylglycine hydrolase family [PF02275.20, score=40.0]} {Human: ENSG00000138744, NAAA, N-acylethanolamine acid amidase, [RH, Score=243, Expect=5e-77]} {Mouse: ENSMUSG00000029413, Naaa, N-acylethanolamine acid amidase, [RH, Score=248, Expect=7e-79]} {Celegans: WBGene00021917, Y55D5A.3, [RH, Score=198, Expect=5e-60]} {RNA1509_56673} {RNA1310_22544, RNA1509_56673} {RNA1509_56673, RNA815_9551.1}
65. MligTC455_24112 7326 152.63 Mlig455_006637, Mlig455_070643

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

CYP2D6, CYP2U1 3.715 0.875 - - 0.974 0.884 0.982

Mlig455_006637 {REF} {Length: 1777} {Pfam: Cytochrome P450 [PF00067.24, score=343.6]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=263, Expect=7e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=263, Expect=2e-81]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=260, Expect=2e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=259, Expect=4e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=2e-79]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=1e-79]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=3e-79]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=257, Expect=4e-79]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=285, Expect=3e-90]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=283, Expect=1e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=278, Expect=2e-87]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=273, Expect=2e-85]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=271, Expect=8e-85]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=271, Expect=1e-84]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=207, Expect=1e-60]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=292, Expect=3e-93]} {RNA1509_10420} {RNA1310_15091.1} {RNA815_4606.2}

Mlig455_070643 {REF} {Length: 2371} {Pfam: Cytochrome P450 [PF00067.24, score=337.1]} {Human: ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=261, Expect=1e-80]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=260, Expect=7e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=259, Expect=3e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=254, Expect=3e-78]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=280, Expect=2e-88]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=279, Expect=7e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=275, Expect=3e-86]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=268, Expect=1e-83]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=268, Expect=1e-83]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=266, Expect=7e-83]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=201, Expect=4e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=288, Expect=2e-91]} {RNA1509_10420, RNA1509_36519} {RNA1310_15091.1, RNA1509_10420, RNA1509_36519} {RNA1509_10420, RNA1509_36519, RNA815_4606.2}
66. MligTC455_43587 981 20.44 Mlig455_064849

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.445

Region-enriched R4: 1.141/0.04839

3.666 - 0.808 - 0.965 0.943 0.950 Mlig455_064849 {REF} {Length: 1597} {RNA1509_13829} {RNA1310_22619, RNA1509_13829} {RNA1509_13829, RNA815_12635}
67. MligTC455_46189 3465 72.19 Mlig455_064483

Neo: -

Age: -

Region-enriched R3: 2.108/0.00000
Region-enriched R4: 1.352/0.02878
Region-enriched R5: 1.186/0.01606

ENPEP 3.656 - 0.846 - 0.932 0.926 0.952 Mlig455_064483 {REF} {Length: 3574} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=253.3]; Peptidase family M1 domain [PF01433.22, score=243.6]; Peptidase M1 N-terminal domain [PF17900.3, score=149.2]} {Human: ENSG00000138792, ENPEP, glutamyl aminopeptidase, [RH, Score=590, Expect=0.0]} {Mouse: ENSMUSG00000028024, Enpep, glutamyl aminopeptidase, [RH, Score=590, Expect=0.0]} {Dmel: FBgn0038135, CG8773, [RH, Score=610, Expect=0.0]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=369, Expect=3e-112]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=479, Expect=2e-153]} {RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985} {RNA1310_3977.1, RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985} {RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985, RNA815_1584}
68. MligTC455_20618 1076 22.42 Mlig455_044808

Neo: -

Age: logFC(26M/2M)=-0.260

Region-enriched R4: 2.047/0.01278

SLC24A5 3.647 0.871 - - 0.953 0.874 0.949 Mlig455_044808 {REF} {Length: 2975} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=180.5]} {Human: ENSG00000188467, SLC24A5, solute carrier family 24 member 5, [RH, Score=378, Expect=2e-125]} {Mouse: ENSMUSG00000035183, Slc24a5, solute carrier family 24, member 5, [RH, Score=378, Expect=1e-125]} {Dmel: FBgn0265767, zyd, zydeco, [Score=359, Expect=2e-118]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=304, Expect=4e-96]} {Smed: dd_Smed_v6_7121_0_1, dd_Smed_v6_7121_0_1, [RH, Score=469, Expect=1e-161]} {RNA1509_11724, RNA1509_31011, RNA1509_4708} {RNA1310_7971.1, RNA1509_11724, RNA1509_31011, RNA1509_4708} {RNA1509_11724, RNA1509_31011, RNA1509_4708, RNA815_7327}
69. MligTC455_44136 8031 167.32 Mlig455_024689, Mlig455_024714

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.859

Region-enriched R4: 1.310/0.01340
Region-enriched R3: 1.215/0.02536

FADS2 3.635 - 0.890 - 0.894 0.894 0.957

Mlig455_024689 {REF} {Length: 3861} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=116.9]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=429, Expect=6e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=426, Expect=8e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=446, Expect=7e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=3e-109]} {RNA1509_1792, RNA1509_9754} {RNA1310_4526, RNA1509_1792, RNA1509_9754} {RNA1509_1792, RNA1509_9754, RNA815_4497}

Mlig455_024714 {REF} {Length: 5232} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=117.3]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=430, Expect=3e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=427, Expect=2e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=447, Expect=3e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=6e-109]} {RNA1509_9754} {RNA1310_4526} {RNA815_4497}
70. MligTC455_39015 2149 44.77 Mlig455_039687, Mlig455_039743

Neo: -

Age: logFC(26M/2M)=1.265

Region-enriched R4: 1.730/0.03079

3.613 0.829 - - 0.955 0.890 0.939

Mlig455_039687 {REF} {Length: 939} {RNA1509_18179} {RNA1310_34151} {RNA815_37566}

Mlig455_039743 {REF} {Length: 939} {RNA1509_18179} {RNA1310_34151} {RNA815_37566}
71. MligTC455_50036 1353 28.19 Mlig455_063714

Neo: -

Age: logFC(26M/2M)=-0.294

Region-enriched R4: 1.826/0.00071
Region-enriched R3: 1.745/0.00078
Region-enriched R5: 1.202/0.01353

SPHK1 3.606 - 0.800 - 0.944 0.887 0.975 Mlig455_063714 {REF} {Length: 3647} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=81.8]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [Score=152, Expect=4e-43]} {Mouse: ENSMUSG00000061878, Sphk1, sphingosine kinase 1, [RH, Score=150, Expect=5e-44]; ENSMUSG00000057342, Sphk2, sphingosine kinase 2, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [RH, Score=145, Expect=1e-39]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [Score=120, Expect=2e-31]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [Score=127, Expect=3e-34]} {RNA1509_19326} {RNA1310_4471} {RNA815_1161}
72. MligTC455_49468 3574 74.46 Mlig455_015846, Mlig455_016064

Neo: -

Age: logFC(26M/2M)=0.226

Region-enriched R3: 1.620/0.01404

SRR 3.593 0.861 - - 0.894 0.883 0.955

Mlig455_015846 {REF} {Length: 2263} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=269.4]; ACT domain [PF01842.27, score=26.5]} {Human: ENSG00000167720, SRR, serine racemase, [Score=169, Expect=3e-47]} {Mouse: ENSMUSG00000001323, Srr, serine racemase, [Score=139, Expect=9e-37]} {Dmel: FBgn0037684, CG8129, [RH, Score=469, Expect=3e-162]} {Celegans: WBGene00010456, K01C8.1, [RH, Score=484, Expect=8e-168]} {Smed: dd_Smed_v6_6737_0_1, dd_Smed_v6_6737_0_1, [Score=555, Expect=0.0]} {RNA1509_3329} {RNA1310_12273.1} {RNA815_4112.1}

Mlig455_016064 {REF} {Length: 2342} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=269.6]; ACT domain [PF01842.27, score=26.5]} {Human: ENSG00000167720, SRR, serine racemase, [Score=167, Expect=6e-47]} {Mouse: ENSMUSG00000001323, Srr, serine racemase, [Score=139, Expect=2e-36]} {Dmel: FBgn0037684, CG8129, [RH, Score=468, Expect=7e-162]} {Celegans: WBGene00010456, K01C8.1, [RH, Score=486, Expect=1e-168]} {Smed: dd_Smed_v6_6737_0_1, dd_Smed_v6_6737_0_1, [Score=558, Expect=0.0]} {RNA1509_3329} {RNA1310_12273.1, RNA1509_3329} {RNA1509_3329, RNA815_4112.1}
73. MligTC455_38613 969 20.2 Mlig455_048005, Mlig455_063705

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.394

Region-enriched R3: 1.570/0.01256

POSTN 3.584 - 0.863 - 0.915 0.847 0.959

Mlig455_048005 {REF} {Length: 629} {Pfam: Fasciclin domain [PF02469.24, score=22.3]} {Smed: dd_Smed_v6_1088_0_1, dd_Smed_v6_1088_0_1, [Score=52.0, Expect=7e-08]} {RNA1509_6801} {RNA1310_9258} {RNA815_5083}

Mlig455_063705 {REF} {Length: 2741} {Pfam: Fasciclin domain [PF02469.24, score=65.6]} {Human: ENSG00000133110, POSTN, periostin, [Score=67.0, Expect=9e-11]} {Mouse: ENSMUSG00000027750, Postn, periostin, osteoblast specific factor, [Score=63.5, Expect=7e-10]} {Smed: dd_Smed_v6_1088_0_1, dd_Smed_v6_1088_0_1, [Score=141, Expect=9e-35]} {RNA1509_45570, RNA1509_6801} {RNA1310_9258, RNA1509_45570, RNA1509_6801} {RNA1509_45570, RNA1509_6801, RNA815_5083}
74. MligTC455_44700 2825 58.85 Mlig455_049079

Neo: -

Age: -

Region-enriched R3: 1.667/0.02565

SLC10A1 3.563 - 0.755 - 0.959 0.894 0.955 Mlig455_049079 {REF} {Length: 2131} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=117.8]; SBF-like CPA transporter family (DUF4137) [PF13593.8, score=36.6]} {Human: ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=124, Expect=4e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=131, Expect=1e-33]} {Dmel: FBgn0030638, CG11655, [Score=154, Expect=2e-41]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=202, Expect=9e-59]} {Smed: dd_Smed_v6_11330_0_1, dd_Smed_v6_11330_0_1, [RH, Score=297, Expect=9e-96]} {RNA1509_41454} {RNA1310_15046, RNA1509_41454} {RNA1509_41454, RNA815_3102}
75. MligTC455_34416 682 14.21 Mlig455_037230

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.502

Region-enriched R3: 1.742/0.02242
Region-enriched R5: 1.658/0.00736

3.551 0.818 0.882 - 0.899 - 0.952 Mlig455_037230 {REF} {Length: 1866} {RNA1509_21160, RNA1509_48851} {RNA1310_6052, RNA1509_21160, RNA1509_48851} {RNA1509_21160, RNA1509_48851, RNA815_3316}
76. MligTC455_52971 2407 50.15 Mlig455_050623

Neo: -

Age: logFC(26M/2M)=-0.616

Region-enriched R4: 1.402/0.00014
Region-enriched R3: 1.372/0.00001

3.549 0.783 0.853 - - 0.959 0.954 Mlig455_050623 {REF} {Length: 1302} {RNA1509_18850, RNA1509_3980, RNA1509_4657} {RNA1310_29014, RNA1509_18850, RNA1509_3980, RNA1509_4657} {RNA1509_18850, RNA1509_3980, RNA1509_4657, RNA815_8071.2}
77. MligTC455_20843 4495 93.65 Mlig455_019749

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.255

ATP1B1 3.547 0.869 - - 0.891 0.836 0.951 Mlig455_019749 {REF} {Length: 1424} {TRANSSPLICED} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=213.7]} {Human: ENSG00000143153, ATP1B1, ATPase Na+/K+ transporting subunit beta 1, [Score=115, Expect=2e-29]} {Mouse: ENSMUSG00000026576, Atp1b1, ATPase, Na+/K+ transporting, beta 1 polypeptide, [Score=115, Expect=5e-30]} {Dmel: FBgn0032946, nrv3, nervana 3, [RH, Score=159, Expect=2e-46]} {Celegans: WBGene00010117, nkb-3, Probable sodium/potassium-transporting ATPase subunit beta-3, [RH, Score=174, Expect=3e-52]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [Score=198, Expect=4e-62]} {RNA1509_10586} {RNA1310_23188.1} {RNA815_9461}
78. MligTC455_53877 1399 29.15 Mlig455_016664

Neo: -

Age: logFC(26M/2M)=0.488

Region-enriched R3: 1.947/0.00083
Region-enriched R4: 1.666/0.01644

CLCA1 3.541 0.820 - - 0.810 0.948 0.963 Mlig455_016664 {REF} {Length: 4164} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=169.0]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=4e-43]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=163, Expect=2e-42]} {RNA1509_1021} {RNA1310_5461.1} {RNA815_1665}
79. MligTC455_43756 3225 67.19 Mlig455_010402

Neo: -

Age: -

Region-enriched R3: 1.722/0.00762

3.534 0.768 - - 0.950 0.872 0.944 Mlig455_010402 {REF} {Length: 2001} {Pfam: Innexin [PF00876.20, score=339.7]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=100, Expect=3e-23]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=291, Expect=2e-95]} {Smed: dd_Smed_v6_734_0_2, dd_Smed_v6_734_0_2, [Score=292, Expect=3e-95]} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1310_16777, RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855, RNA815_7295}
80. MligTC455_38362 1015 21.16 Mlig455_045508

Neo: -

Age: -

Region-enriched R4: 1.693/0.01745
Region-enriched R5: 1.163/0.02906

AADAC 3.511 0.750 - - 0.960 0.879 0.922 Mlig455_045508 {REF} {Length: 2224} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=113.1]; Carboxylesterase family [PF00135.30, score=19.9]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=96.3, Expect=2e-21]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=93.6, Expect=2e-20]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=102, Expect=1e-23]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=98.2, Expect=3e-22]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=65.5, Expect=4e-11]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=98.2, Expect=2e-22]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=82.0, Expect=5e-17]} {RNA1509_14307} {RNA1310_15560.2} {RNA815_8354}
81. MligTC455_50448 759 15.81 Mlig455_064452

Neo: -

Age: logFC(26M/2M)=-0.850

KREMEN1 3.495 0.773 - - 0.927 0.828 0.967 Mlig455_064452 {REF} {Length: 819} {Pfam: WSC domain [PF01822.21, score=61.7]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=52.4, Expect=9e-08]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=50.8, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.9, Expect=1e-08]} {RNA1509_12393} {RNA1310_56240.1} {RNA815_26405}
82. MligTC455_16257 1877 39.1 Mlig455_026808, Mlig455_030881

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.209/0.00209
Region-enriched R3: 1.663/0.01717
Region-enriched R5: 1.364/0.02606

STOM 3.491 - 0.715 - 0.927 0.878 0.971

Mlig455_026808 {REF} {Length: 1301} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=20.6]} {Human: ENSG00000148175, STOM, stomatin, [Score=123, Expect=2e-35]; ENSG00000133115, STOML3, stomatin like 3, [Score=118, Expect=1e-33]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=123, Expect=2e-35]; ENSMUSG00000027744, Stoml3, stomatin (Epb7.2)-like 3, [Score=120, Expect=2e-34]; ENSMUSG00000026602, Nphs2, nephrosis 2, podocin, [Score=117, Expect=2e-32]} {Dmel: FBgn0260657, CG42540, [Score=126, Expect=5e-36]} {Celegans: WBGene00006068, sto-6, STOmatin, [Score=140, Expect=1e-42]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=148, Expect=1e-45]} {RNA1509_6816} {RNA1310_26895} {RNA815_11983}

Mlig455_030881 {REF} {Length: 1405} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=110.3]; SPFH domain-Band 7 family [PF13421.8, score=20.7]} {Human: ENSG00000148175, STOM, stomatin, [Score=335, Expect=3e-115]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=323, Expect=5e-111]} {Dmel: FBgn0260657, CG42540, [Score=323, Expect=2e-109]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=335, Expect=4e-114]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=362, Expect=1e-126]} {RNA1509_6816} {RNA1310_26895, RNA1509_6816} {RNA1509_6816, RNA815_11983}
83. MligTC455_48498 1066 22.21 Mlig455_007871

Neo: -

Age: logFC(26M/2M)=0.286

Region-enriched R3: 1.717/0.03337

MICU3 3.461 - 0.814 - 0.855 0.831 0.961 Mlig455_007871 {REF} {Length: 2576} {Pfam: EF-hand domain pair [PF13499.8, score=34.5]; EF-hand domain [PF13405.8, score=34.4]; EF-hand domain pair [PF13833.8, score=32.0]; EF hand [PF00036.34, score=30.6]; EF hand [PF13202.8, score=22.8]} {Human: ENSG00000155970, MICU3, mitochondrial calcium uptake family member 3, [Score=260, Expect=1e-82]} {Mouse: ENSMUSG00000021973, Micu2, mitochondrial calcium uptake 2, [Score=216, Expect=3e-65]; ENSMUSG00000039478, Micu3, mitochondrial calcium uptake family, member 3, [Score=214, Expect=2e-63]} {Dmel: FBgn0038735, CG4662, [Score=282, Expect=3e-90]} {Celegans: WBGene00008345, C56A3.6, [RH, Score=239, Expect=1e-74]} {Smed: dd_Smed_v6_5430_0_1, dd_Smed_v6_5430_0_1, [Score=204, Expect=9e-61]} {RNA1509_14710, RNA1509_26156} {RNA1310_3702, RNA1509_14710, RNA1509_26156} {RNA1509_14710, RNA1509_26156, RNA815_171.2}
84. MligTC455_46449 3887 80.98 Mlig455_019880

Neo: -

Age: -

LTA4H 3.44 0.732 - - 0.822 0.931 0.955 Mlig455_019880 {REF} {Length: 2573} {Pfam: Peptidase family M1 domain [PF01433.22, score=145.8]; Leukotriene A4 hydrolase, C-terminal [PF09127.13, score=108.1]; Peptidase M1 N-terminal domain [PF17900.3, score=93.8]} {Human: ENSG00000111144, LTA4H, leukotriene A4 hydrolase, [RH, Score=564, Expect=0.0]} {Mouse: ENSMUSG00000015889, Lta4h, leukotriene A4 hydrolase, [RH, Score=559, Expect=0.0]} {Dmel: FBgn0032721, CG10602, [RH, Score=450, Expect=4e-149]} {Celegans: WBGene00022610, ZC416.6, [RH, Score=514, Expect=9e-174]} {Smed: dd_Smed_v6_733_0_1, dd_Smed_v6_733_0_1, [RH, Score=492, Expect=1e-165]} {RNA1509_18056} {RNA1310_8038} {RNA815_3569}
85. MligTC455_37238 1196 24.92 Mlig455_049614

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.981

Region-enriched R3: 1.482/0.00582

PANK4 3.43 0.821 - - 0.955 0.738 0.916 Mlig455_049614 {REF} {Length: 1474} {Pfam: Fumble [PF03630.16, score=119.6]} {Human: ENSG00000157881, PANK4, pantothenate kinase 4, [Score=104, Expect=9e-24]; ENSG00000273494, PANK4, pantothenate kinase 4, [Score=104, Expect=9e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=95.9, Expect=4e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=65.1, Expect=3e-11]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=173, Expect=7e-51]} {RNA1509_8444} {RNA1310_20224, RNA1509_8444} {RNA1509_8444, RNA815_7673}
86. MligTC455_33005 823 17.14 Mlig455_042741

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.698

Region-enriched R3: 2.290/0.00003
Region-enriched R4: 1.977/0.00130
Region-enriched R5: 1.201/0.04793

3.427 0.701 0.904 - 0.859 - 0.963 Mlig455_042741 {REF} {Length: 1301} {RNA1509_4524} {RNA1310_31808} {RNA815_13487}
87. MligTC455_19366 2365 49.28 Mlig455_029830

Neo: -

Age: -

Region-enriched R3: 1.992/0.00057
Region-enriched R5: 1.418/0.01296

PANK3 3.403 0.817 - 0.834 0.964 0.788 - Mlig455_029830 {REF} {Length: 1495} {Pfam: Fumble [PF03630.16, score=108.9]} {Human: ENSG00000120137, PANK3, pantothenate kinase 3, [Score=57.0, Expect=2e-08]; ENSG00000152782, PANK1, pantothenate kinase 1, [Score=56.6, Expect=3e-08]; ENSG00000125779, PANK2, pantothenate kinase 2, [Score=55.1, Expect=5e-08]} {Mouse: ENSMUSG00000018846, Pank3, pantothenate kinase 3, [Score=56.6, Expect=2e-08]; ENSMUSG00000033610, Pank1, pantothenate kinase 1, [Score=56.2, Expect=2e-08]; ENSMUSG00000037514, Pank2, pantothenate kinase 2, [Score=55.8, Expect=4e-08]} {Dmel: FBgn0011205, fbl, fumble, [Score=55.1, Expect=5e-08]} {Smed: dd_Smed_v6_994_0_1, dd_Smed_v6_994_0_1, [RH, Score=227, Expect=2e-71]} {RNA1509_1801} {RNA1310_24657, RNA1509_1801} {RNA1509_1801, RNA815_10326}
88. MligTC455_27869 8765 182.6 Mlig455_051857, Mlig455_051868, Mlig455_051893

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.214/0.00040
Region-enriched R5: 1.603/0.01133

ANPEP 3.401 0.893 - 0.781 0.771 0.956 -

Mlig455_051857 {REF} {Length: 3680} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=238.0]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=560, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=546, Expect=6e-179]} {Dmel: FBgn0039640, CG14516, [RH, Score=536, Expect=1e-174]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=599, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051868 {REF} {Length: 4344} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=259.5]; Peptidase family M1 domain [PF01433.22, score=234.1]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=552, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [Score=542, Expect=4e-177]} {Dmel: FBgn0039640, CG14516, [RH, Score=529, Expect=7e-172]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=406, Expect=1e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=595, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}

Mlig455_051893 {REF} {Length: 4373} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=260.1]; Peptidase family M1 domain [PF01433.22, score=236.2]; Peptidase M1 N-terminal domain [PF17900.3, score=137.9]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [Score=558, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=545, Expect=3e-178]} {Dmel: FBgn0039640, CG14516, [RH, Score=533, Expect=2e-173]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=405, Expect=2e-125]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=596, Expect=0.0]} {RNA1509_5196} {RNA1310_2955.1} {RNA815_759.2}
89. MligTC455_39261 2000 41.67 Mlig455_036509, Mlig455_069140

Neo: -

Age: logFC(26M/2M)=-0.812

3.345 0.771 - 0.710 0.891 - 0.973

Mlig455_036509 {REF} {Length: 2142} {RNA1509_28747} {RNA1310_48185.2} {RNA815_28254}

Mlig455_069140 {REF} {Length: 3743} {RNA1509_28747, RNA1509_33325, RNA1509_34343} {RNA1310_46864, RNA1509_28747, RNA1509_33325, RNA1509_34343} {RNA1509_28747, RNA1509_33325, RNA1509_34343, RNA815_28254}
90. MligTC455_20619 2288 47.67 Mlig455_055574

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.591/0.00258
Region-enriched R4: 1.303/0.03358

SLC24A5 3.34 0.750 - 0.751 - 0.889 0.950 Mlig455_055574 {REF} {Length: 3527} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=180.5]} {Human: ENSG00000188467, SLC24A5, solute carrier family 24 member 5, [RH, Score=378, Expect=2e-125]} {Mouse: ENSMUSG00000035183, Slc24a5, solute carrier family 24, member 5, [RH, Score=378, Expect=1e-125]} {Dmel: FBgn0265767, zyd, zydeco, [Score=359, Expect=2e-118]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=304, Expect=4e-96]} {Smed: dd_Smed_v6_7121_0_1, dd_Smed_v6_7121_0_1, [RH, Score=469, Expect=1e-161]} {RNA1509_4708} {RNA1310_7971.1} {RNA815_7327}
91. MligTC455_41866 2789 58.1 Mlig455_053658, Mlig455_053662

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.383

Region-enriched R3: 2.037/0.00117

AC113554.1, ACE 3.333 0.806 0.734 - - 0.961 0.832

Mlig455_053658 {REF} {Length: 2590} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=652.1]} {Human: ENSG00000264813, AC113554.1, novel transcript, [Score=461, Expect=2e-153]; ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=461, Expect=2e-153]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=459, Expect=1e-146]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [RH, Score=441, Expect=2e-147]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [RH, Score=212, Expect=1e-58]} {Smed: dd_Smed_v6_6160_0_1, dd_Smed_v6_6160_0_1, [Score=358, Expect=2e-115]} {RNA1509_21944} {RNA1310_8120.1} {RNA815_2871.1}

Mlig455_053662 {REF} {Length: 2655} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=648.5]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=462, Expect=3e-148]; ENSG00000264813, AC113554.1, novel transcript, [Score=461, Expect=4e-153]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=457, Expect=3e-146]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [RH, Score=437, Expect=1e-145]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [RH, Score=209, Expect=9e-58]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=361, Expect=2e-116]} {RNA1509_21944, RNA1509_37454, RNA1509_37991} {RNA1310_8120.1, RNA1509_37454, RNA1509_37991} {RNA1509_37454, RNA1509_37991, RNA815_2871.1}
92. MligTC455_47835 636 13.24 Mlig455_043525

Neo: -

Age: -

Region-enriched R3: 2.659/0.00001
Region-enriched R6: 2.142/0.00461
Region-enriched R5: 1.917/0.00072

3.315 0.819 0.818 - - 0.725 0.953 Mlig455_043525 {REF} {Length: 1356} {RNA1509_18381, RNA1509_27428, RNA1509_57910} {RNA1310_28727.1, RNA1509_18381, RNA1509_27428, RNA1509_57910} {RNA1509_18381, RNA1509_27428, RNA1509_57910, RNA815_19848}
93. MligTC455_40820 1076 22.41 Mlig455_016774

Neo: -

Age: logFC(26M/2M)=0.366

Region-enriched R4: 1.989/0.00476

DCXR 3.312 - - 0.716 0.840 0.795 0.961 Mlig455_016774 {REF} {Length: 1162} {TRANSSPLICED} {Pfam: Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=186.1]; short chain dehydrogenase [PF00106.27, score=156.4]; KR domain [PF08659.12, score=55.4]; NAD dependent epimerase/dehydratase family [PF01370.23, score=28.6]; RmlD substrate binding domain [PF04321.19, score=23.1]} {Human: ENSG00000169738, DCXR, dicarbonyl and L-xylulose reductase, [RH, Score=182, Expect=9e-57]} {Mouse: ENSMUSG00000039450, Dcxr, dicarbonyl L-xylulose reductase, [RH, Score=188, Expect=2e-59]} {Dmel: FBgn0030968, CG7322, [RH, Score=194, Expect=1e-61]} {Celegans: WBGene00000984, dhs-21, L-xylulose reductase, [RH, Score=204, Expect=9e-66]} {Smed: dd_Smed_v6_2263_0_1, dd_Smed_v6_2263_0_1, [RH, Score=183, Expect=1e-57]} {RNA1509_36359, RNA1509_42063, RNA1509_55127} {RNA1310_24446.2, RNA1509_36359, RNA1509_42063, RNA1509_55127} {RNA1509_36359, RNA1509_42063, RNA1509_55127, RNA815_13838}
94. MligTC455_36727 2161 45.01 Mlig455_013407, Mlig455_013448

Neo: -

Age: logFC(26M/2M)=-0.438

Region-enriched R3: 1.447/0.00030

3.297 0.739 0.760 - 0.958 0.840 -

Mlig455_013407 {REF} {Length: 3635} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1310_1688.1, RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611, RNA815_14547}

Mlig455_013448 {REF} {Length: 3532} {RNA1509_17696} {RNA1310_1688.1} {RNA815_14547}
95. MligTC455_49840 1487 30.98 Mlig455_054770, Mlig455_054797

Neo: -

Age: -

Region-enriched R3: 1.670/0.00009
Region-enriched R5: 1.605/0.00002
Region-enriched R4: 1.351/0.01428

ECE1 3.252 - 0.701 - 0.956 0.770 0.825

Mlig455_054770 {REF} {Length: 3217} {Pfam: Peptidase family M13 [PF05649.15, score=200.5]; Peptidase family M13 [PF01431.23, score=91.3]} {Human: ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=179, Expect=1e-46]; ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=177, Expect=1e-45]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=177, Expect=1e-45]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=174, Expect=7e-45]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=190, Expect=2e-50]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=182, Expect=2e-47]} {Celegans: WBGene00020230, nep-2, Neprilysin-2, [Score=154, Expect=9e-39]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=160, Expect=7e-41]} {RNA1509_3125} {RNA1310_4911.1, RNA1509_3125} {RNA1509_3125, RNA815_2994}

Mlig455_054797 {REF} {Length: 3127} {Pfam: Peptidase family M13 [PF05649.15, score=200.5]; Peptidase family M13 [PF01431.23, score=92.9]} {Human: ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=182, Expect=2e-47]; ENSG00000142606, MMEL1, membrane metalloendopeptidase like 1, [Score=179, Expect=1e-46]; ENSG00000277131, MMEL1, membrane metalloendopeptidase like 1, [Score=179, Expect=1e-46]; ENSG00000171551, ECEL1, endothelin converting enzyme like 1, [Score=177, Expect=1e-45]; ENSG00000196549, MME, membrane metalloendopeptidase, [Score=173, Expect=1e-44]} {Mouse: ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=193, Expect=2e-51]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=184, Expect=3e-48]} {Celegans: WBGene00020230, nep-2, Neprilysin-2, [Score=157, Expect=1e-39]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=163, Expect=8e-42]} {RNA1509_3125} {RNA1310_4911.1} {RNA815_2994}
96. MligTC455_18367 1075 22.4 Mlig455_026355, Mlig455_052709

Neo: -

Age: Down-Up-Down

Region-enriched R3: 1.864/0.00790

IFI30 3.233 0.790 0.762 - - 0.722 0.959

Mlig455_026355 {REF} {Length: 1072} {Pfam: Gamma interferon inducible lysosomal thiol reductase (GILT) [PF03227.18, score=100.5]} {Human: ENSG00000216490, IFI30, IFI30, lysosomal thiol reductase, [RH, Score=142, Expect=3e-41]} {Mouse: ENSMUSG00000110777, Ifi30, interferon gamma inducible protein 30, [RH, Score=122, Expect=9e-34]} {Dmel: FBgn0085638, CG41378, [Score=93.2, Expect=3e-23]} {Celegans: WBGene00009514, F37H8.5, GILT-like protein F37H8.5, [Score=98.2, Expect=2e-24]} {Smed: dd_Smed_v6_2024_0_1, dd_Smed_v6_2024_0_1, [Score=114, Expect=1e-31]} {RNA1509_51694} {RNA1310_32351.1} {RNA815_17592}

Mlig455_052709 {REF} {Length: 1087} {Pfam: Gamma interferon inducible lysosomal thiol reductase (GILT) [PF03227.18, score=100.5]} {Human: ENSG00000216490, IFI30, IFI30, lysosomal thiol reductase, [RH, Score=142, Expect=3e-41]} {Mouse: ENSMUSG00000110777, Ifi30, interferon gamma inducible protein 30, [RH, Score=122, Expect=9e-34]} {Dmel: FBgn0085638, CG41378, [Score=93.2, Expect=3e-23]} {Celegans: WBGene00009514, F37H8.5, GILT-like protein F37H8.5, [Score=98.2, Expect=2e-24]} {Smed: dd_Smed_v6_2024_0_1, dd_Smed_v6_2024_0_1, [Score=114, Expect=1e-31]} {RNA1509_35702, RNA1509_51694} {RNA1310_32351.1, RNA1509_35702} {RNA1509_35702, RNA815_17592}
97. MligTC455_04549 296 6.16 Mlig455_047043

Neo: -

Age: logFC(26M/2M)=0.556

Region-enriched R3: 2.204/0.00044
Region-enriched R4: 1.879/0.02998
Region-enriched R5: 1.340/0.03066

TYMP 3.213 0.736 0.763 - - 0.754 0.960 Mlig455_047043 {REF} {Length: 2149} {TRANSSPLICED} {Pfam: Glycosyl transferase family, a/b domain [PF00591.23, score=114.4]; Glycosyl transferase family, helical bundle domain [PF02885.19, score=55.5]; Pyrimidine nucleoside phosphorylase C-terminal domain [PF07831.15, score=27.3]} {Human: ENSG00000025708, TYMP, thymidine phosphorylase, [RH, Score=324, Expect=7e-106]} {Mouse: ENSMUSG00000022615, Tymp, thymidine phosphorylase, [RH, Score=320, Expect=1e-104]} {Smed: dd_Smed_v6_869_0_1, dd_Smed_v6_869_0_1, [RH, Score=323, Expect=2e-106]} {RNA1509_12879} {RNA1310_13641} {RNA815_1859}
98. MligTC455_48012 225 4.68 Mlig455_021532

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.619/0.00051

3.178 0.754 - - 0.761 0.712 0.951 Mlig455_021532 {REF} {Length: 854} {Celegans: WBGene00044743, crb-3, Drosophila CRumBs homolog, [RH, Score=44.7, Expect=2e-07]} {RNA1509_16097} {RNA1310_12897} {RNA815_7368}
99. MligTC455_35665 550 11.46 Mlig455_000411

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.492

AC099489.1 2.841 - - - 0.963 0.931 0.947 Mlig455_000411 {REF} {Length: 12958} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=89.4]; Domain of unknown function (DUF1943) [PF09172.13, score=66.3]; von Willebrand factor type D domain [PF00094.27, score=25.5]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=122, Expect=1e-26]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=74.3, Expect=3e-12]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=93.6, Expect=3e-18]} {RNA1509_862} {RNA1310_65.2} {RNA815_55}
100. MligTC455_20135 1861 38.76 Mlig455_051349

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.876

Region-enriched R4: 2.367/0.00063
Region-enriched R5: 1.267/0.03902

ATP1B2 2.804 - - - 0.923 0.924 0.957 Mlig455_051349 {REF} {Length: 1394} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=191.3]} {Human: ENSG00000129244, ATP1B2, ATPase Na+/K+ transporting subunit beta 2, [Score=102, Expect=2e-24]} {Mouse: ENSMUSG00000041329, Atp1b2, ATPase, Na+/K+ transporting, beta 2 polypeptide, [Score=102, Expect=2e-24]} {Dmel: FBgn0015777, nrv2, nervana 2, [Score=145, Expect=2e-40]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=151, Expect=7e-43]} {Smed: dd_Smed_v6_2230_0_4, dd_Smed_v6_2230_0_4, [RH, Score=211, Expect=2e-66]} {RNA1509_2976} {RNA1310_26809} {RNA815_11848}

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