Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_22632 | 17908 | 373.08 | Mlig455_056621 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.479 Region-enriched R3: 3.047/0.00000 |
TMPRSS9 | Mlig455_056621 {REF} {Length: 1688} {Pfam: Trypsin [PF00089.28, score=252.4]; CUB domain [PF00431.22, score=105.1]; Low-density lipoprotein receptor domain class A [PF00057.20, score=46.9]; Trypsin-like peptidase domain [PF13365.8, score=33.6]; Domain of unknown function (DUF1986) [PF09342.13, score=28.8]} {Human: ENSG00000178297, TMPRSS9, transmembrane serine protease 9, [RH, Score=218, Expect=1e-62]; ENSG00000122194, PLG, plasminogen, [RH, Score=216, Expect=5e-62]; ENSG00000187950, OVCH1, ovochymase 1, [RH, Score=210, Expect=3e-59]; ENSG00000149418, ST14, suppression of tumorigenicity 14, [RH, Score=209, Expect=1e-59]} {Mouse: ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [RH, Score=216, Expect=1e-61]; ENSMUSG00000031995, St14, suppression of tumorigenicity 14 (colon carcinoma), [RH, Score=213, Expect=7e-61]} {Dmel: FBgn0033192, Corin, [RH, Score=182, Expect=5e-50]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=166, Expect=7e-48]} {Smed: dd_Smed_v6_2492_0_1, dd_Smed_v6_2492_0_1, [Score=167, Expect=5e-48]} {RNA1509_254} {RNA1310_22739.1} {RNA815_6357.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 0.716 | 8.625 | 0.29976 | 0.94939 | |
RegionR2 | -2.594 | 8.625 | 0.00097 | 0.02134 | |
RegionR3 | 3.047 | 8.625 | 0.00000 | 0.00000 | |
RegionR4 | 1.888 | 8.625 | 0.00364 | 0.02834 | |
RegionR5 | 1.451 | 8.625 | 0.01050 | 0.05986 | |
RegionR6 | -1.635 | 8.625 | 0.01988 | 0.25391 | |
RegionR7 | -1.496 | 8.625 | 0.03120 | 0.33616 | |
RegionR8 | -1.376 | 8.625 | 0.06464 | 0.49281 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.284 | 8.625 | 0.74097 | 1.00000 | |
RegenerationR2 | 0.781 | 8.625 | 0.33400 | 0.77038 | |
RegenerationR3 | -1.203 | 8.625 | 0.14053 | 0.56667 | |
RegenerationR4 | -1.242 | 8.625 | 0.13968 | 0.56143 | |
RegenerationR5 | -1.734 | 8.625 | 0.03491 | 0.31104 | |
RegenerationR6 | 0.255 | 8.625 | 0.74843 | 0.95155 | |
RegenerationBL | -0.961 | 8.625 | 0.18805 | 0.52046 | |
RegenerationTP | 0.141 | 8.625 | 0.85201 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_22632 | 17908 | 373.08 | Mlig455_056621 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.479 Region-enriched R3: 3.047/0.00000 |
TMPRSS9 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_056621 {REF} {Length: 1688} {Pfam: Trypsin [PF00089.28, score=252.4]; CUB domain [PF00431.22, score=105.1]; Low-density lipoprotein receptor domain class A [PF00057.20, score=46.9]; Trypsin-like peptidase domain [PF13365.8, score=33.6]; Domain of unknown function (DUF1986) [PF09342.13, score=28.8]} {Human: ENSG00000178297, TMPRSS9, transmembrane serine protease 9, [RH, Score=218, Expect=1e-62]; ENSG00000122194, PLG, plasminogen, [RH, Score=216, Expect=5e-62]; ENSG00000187950, OVCH1, ovochymase 1, [RH, Score=210, Expect=3e-59]; ENSG00000149418, ST14, suppression of tumorigenicity 14, [RH, Score=209, Expect=1e-59]} {Mouse: ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [RH, Score=216, Expect=1e-61]; ENSMUSG00000031995, St14, suppression of tumorigenicity 14 (colon carcinoma), [RH, Score=213, Expect=7e-61]} {Dmel: FBgn0033192, Corin, [RH, Score=182, Expect=5e-50]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=166, Expect=7e-48]} {Smed: dd_Smed_v6_2492_0_1, dd_Smed_v6_2492_0_1, [Score=167, Expect=5e-48]} {RNA1509_254} {RNA1310_22739.1} {RNA815_6357.1} |
2. | MligTC455_22631 | 17842 | 371.71 | Mlig455_007773 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=0.952 Region-enriched R3: 3.041/0.00000 |
TMPRSS9 | 5.998 | 1.000 | 1.000 | 1.000 | 0.998 | 1.000 | 1.000 | Mlig455_007773 {REF} {Length: 1686} {Pfam: Trypsin [PF00089.28, score=249.9]; CUB domain [PF00431.22, score=105.1]; Low-density lipoprotein receptor domain class A [PF00057.20, score=46.9]; Trypsin-like peptidase domain [PF13365.8, score=33.1]; Domain of unknown function (DUF1986) [PF09342.13, score=27.4]} {Human: ENSG00000178297, TMPRSS9, transmembrane serine protease 9, [RH, Score=218, Expect=9e-63]; ENSG00000122194, PLG, plasminogen, [RH, Score=211, Expect=1e-60]; ENSG00000149418, ST14, suppression of tumorigenicity 14, [RH, Score=208, Expect=3e-59]} {Mouse: ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [RH, Score=217, Expect=1e-61]; ENSMUSG00000031995, St14, suppression of tumorigenicity 14 (colon carcinoma), [RH, Score=211, Expect=2e-60]; ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [RH, Score=209, Expect=1e-59]} {Dmel: FBgn0033192, Corin, [RH, Score=184, Expect=1e-50]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=165, Expect=9e-48]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=175, Expect=1e-47]} {RNA1509_10189, RNA1509_254, RNA1509_423, RNA1509_8940} {RNA1310_22739.1, RNA1509_10189, RNA1509_254, RNA1509_423, RNA1509_8940} {RNA1509_10189, RNA1509_254, RNA1509_423, RNA1509_8940, RNA815_6357.1} |
3. | MligTC455_40106 | 12022 | 250.46 | Mlig455_062776 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.171 Region-enriched R3: 2.894/0.00000 |
5.503 | 0.954 | 0.934 | 0.959 | 0.983 | 0.714 | 0.959 | Mlig455_062776 {REF} {Length: 2372} {Pfam: D-lyxose isomerase [PF07385.14, score=40.7]; Glutathione-dependent formaldehyde-activating enzyme [PF04828.16, score=22.1]} {RNA1509_347} {RNA1310_44581.1} {RNA815_12017.1} | |
4. | MligTC455_40105 | 3325 | 69.27 | Mlig455_003114 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.346 Region-enriched R3: 3.660/0.00002 |
5.065 | 0.952 | 0.935 | 0.819 | 0.834 | 0.821 | 0.704 | Mlig455_003114 {REF} {Length: 1338} {Pfam: D-lyxose isomerase [PF07385.14, score=33.9]} {RNA1509_20545, RNA1509_54742} {RNA1310_52351, RNA1509_54742} {RNA1509_54742, RNA815_12017.1} | |
5. | MligTC455_30405 | 15479 | 322.49 | Mlig455_010004, Mlig455_010049 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.566 Region-enriched R3: 3.633/0.00000 |
CPA2 | 4.568 | 0.972 | 0.894 | 0.919 | 0.957 | - | 0.826 | Mlig455_010004 {REF} {Length: 1499} {Pfam: Zinc carboxypeptidase [PF00246.26, score=261.4]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2, [Score=221, Expect=5e-67]} {Mouse: ENSMUSG00000071553, Cpa2, carboxypeptidase A2, pancreatic, [Score=228, Expect=6e-70]} {Dmel: FBgn0032144, CG17633, [RH, Score=240, Expect=1e-74]} {Celegans: WBGene00020281, T06A4.1, [Score=214, Expect=3e-63]} {Smed: dd_Smed_v6_2541_0_1, dd_Smed_v6_2541_0_1, [RH, Score=257, Expect=2e-81]} {RNA1509_334, RNA1509_3364} {RNA1310_22015, RNA1509_334, RNA1509_3364} {RNA1509_334, RNA1509_3364, RNA815_8491} Mlig455_010049 {REF} {Length: 1546} {Pfam: Zinc carboxypeptidase [PF00246.26, score=261.1]} {Human: ENSG00000158516, CPA2, carboxypeptidase A2, [Score=220, Expect=2e-66]} {Mouse: ENSMUSG00000071553, Cpa2, carboxypeptidase A2, pancreatic, [Score=227, Expect=3e-69]} {Dmel: FBgn0032144, CG17633, [RH, Score=242, Expect=3e-75]} {Celegans: WBGene00020281, T06A4.1, [Score=215, Expect=2e-63]} {Smed: dd_Smed_v6_2541_0_1, dd_Smed_v6_2541_0_1, [RH, Score=257, Expect=3e-81]} {RNA1509_334} {RNA1310_22015} {RNA815_8491} |
6. | MligTC455_50368 | 16261 | 338.78 | Mlig455_009542 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.173 Region-enriched R3: 3.112/0.00000 |
4.517 | 0.932 | 0.883 | 0.817 | 0.927 | - | 0.958 | Mlig455_009542 {REF} {Length: 524} {RNA1509_1137, RNA1509_491, RNA1509_924} {RNA1310_65230.2, RNA1509_1137, RNA1509_491, RNA1509_924} {RNA1509_1137, RNA1509_491, RNA1509_924, RNA815_32028.1} | |
7. | MligTC455_22525 | 12941 | 269.61 | Mlig455_012844 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=1.410 Region-enriched R3: 3.654/0.00000 |
4.398 | 0.859 | 0.895 | 0.794 | 0.976 | - | 0.874 | Mlig455_012844 {REF} {Length: 1508} {TRANSSPLICED} {Pfam: Group 7 allergen [PF16984.7, score=99.1]; Haemolymph juvenile hormone binding protein (JHBP) [PF06585.13, score=27.2]} {RNA1509_13349, RNA1509_2078} {RNA1310_21535.1, RNA1509_2078} {RNA1509_2078, RNA815_6279.1} | |
8. | MligTC455_26184 | 7464 | 155.49 | Mlig455_021322 | Neo: Germline Age: - Region-enriched R3: 2.553/0.00001 |
4.175 | 0.951 | 0.859 | 0.818 | 0.750 | - | 0.797 | Mlig455_021322 {REF} {Length: 496} {TRANSSPLICED} {Pfam: Pacifastin inhibitor (LCMII) [PF05375.15, score=31.0]} {RNA1509_2946, RNA1509_56087, RNA1509_7601} {RNA1310_20339, RNA1509_2946, RNA1509_56087, RNA1509_7601} {RNA1509_2946, RNA1509_56087, RNA1509_7601, RNA815_31444.2} | |
9. | MligTC455_51489 | 2466 | 51.38 | Mlig455_070231 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=1.381 Region-enriched R3: 4.130/0.00000 |
4.154 | 0.786 | 0.779 | 0.831 | 0.955 | - | 0.803 | Mlig455_070231 {REF} {Length: 1931} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=34.7]} {RNA1509_10905, RNA1509_14804, RNA1509_15784, RNA1509_16980} {RNA1310_19974, RNA1509_10905, RNA1509_14804, RNA1509_15784, RNA1509_16980} {RNA1509_10905, RNA1509_14804, RNA1509_15784, RNA1509_16980, RNA815_8492} | |
10. | MligTC455_36393 | 17515 | 364.89 | Mlig455_045161 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.767 Region-enriched R3: 2.754/0.00001 |
PROC | 4.078 | 0.820 | 0.818 | 0.764 | 0.724 | - | 0.952 | Mlig455_045161 {REF} {Length: 1434} {Pfam: Trypsin [PF00089.28, score=98.2]; Trypsin-like peptidase domain [PF13365.8, score=38.3]} {Human: ENSG00000115718, PROC, protein C, inactivator of coagulation factors Va and VIIIa, [Score=67.0, Expect=3e-12]} {Mouse: ENSMUSG00000024386, Proc, protein C, [Score=75.9, Expect=2e-15]; ENSMUSG00000034039, Prss29, protease, serine 29, [Score=73.6, Expect=4e-15]} {Dmel: FBgn0036738, CG7542, [Score=77.0, Expect=1e-16]} {Celegans: WBGene00006621, try-3, TRYpsin-like protease, [Score=48.1, Expect=1e-06]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [RH, Score=111, Expect=4e-30]} {RNA1509_18309, RNA1509_2871, RNA1509_29, RNA1509_44950, RNA1509_5544} {RNA1310_47138.1, RNA1509_18309, RNA1509_2871, RNA1509_44950, RNA1509_5544} {RNA1509_18309, RNA1509_2871, RNA1509_44950, RNA1509_5544, RNA815_8541.1} |
11. | MligTC455_36181 | 465 | 9.68 | Mlig455_066565 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.101 Region-enriched R3: 2.467/0.01877 |
PLB1 | 3.492 | 0.972 | 0.789 | - | 0.926 | - | 0.805 | Mlig455_066565 {REF} {Length: 2233} {Pfam: GDSL-like Lipase/Acylhydrolase [PF00657.24, score=77.7]; GDSL-like Lipase/Acylhydrolase family [PF13472.8, score=39.7]} {Human: ENSG00000163803, PLB1, phospholipase B1, [RH, Score=291, Expect=1e-87]} {Mouse: ENSMUSG00000029134, Plb1, phospholipase B1, [RH, Score=308, Expect=1e-93]} {Dmel: FBgn0036939, CG7365, [Score=236, Expect=2e-73]} {Celegans: WBGene00022256, Y73B6BL.37, [RH, Score=244, Expect=4e-77]} {Smed: dd_Smed_v6_2690_0_1, dd_Smed_v6_2690_0_1, [Score=230, Expect=2e-71]} {RNA1509_30374} {RNA1310_16463} {RNA815_8760} |
12. | MligTC455_31554 | 12688 | 264.32 | Mlig455_003094 | Neo: - Age: Down-Up-Down Region-enriched R4: 2.454/0.01927 |
2.536 | - | 0.762 | 0.815 | - | - | 0.959 | Mlig455_003094 {REF} {Length: 2681} {Pfam: Wolframin Sel1-like repeat [PF20023.1, score=52.7]; Crp-like helix-turn-helix domain [PF13545.8, score=50.3]; 4'-phosphopantetheinyl transferase superfamily [PF01648.22, score=47.0]; Family of unknown function (DUF6307) [PF19826.1, score=42.0]; MarR family [PF01047.24, score=38.3]; Ribosomal protein L10 [PF00466.22, score=38.1]; Skp1 family, tetramerisation domain [PF03931.17, score=35.7]; PASTA domain [PF03793.21, score=32.0]; Family of unknown function (DUF6470) [PF20074.1, score=32.0]; D-lactate dehydrogenase, membrane binding [PF09330.13, score=30.1]; SprT-like family [PF10263.11, score=26.5]; winged helix-turn-helix [PF16221.7, score=26.3]; CUT domain [PF02376.17, score=24.1]; Helicase HerA, central domain [PF01935.19, score=22.5]; Bpu10I restriction endonuclease [PF09549.12, score=22.1]; von Willebrand factor type A domain [PF13768.8, score=21.6]; Protein of unknown function (DUF1340) [PF07067.13, score=21.0]; Mobile element transfer protein [PF05122.15, score=18.8]} {RNA1509_27680} {RNA1310_14862.1} {RNA815_5816} | |
13. | MligTC455_21679 | 909 | 18.93 | Mlig455_030321 | Neo: - Age: logFC(26M/2M)=0.449 Region-enriched R4: 2.289/0.00034 |
ENDOU | 2.404 | 0.747 | - | - | - | 0.705 | 0.952 | Mlig455_030321 {REF} {Length: 1399} {Pfam: Endoribonuclease XendoU [PF09412.12, score=171.6]} {Human: ENSG00000111405, ENDOU, endonuclease, poly(U) specific, [Score=124, Expect=3e-32]} {Mouse: ENSMUSG00000022468, Endou, endonuclease, polyU-specific, [Score=125, Expect=2e-32]} {Dmel: FBgn0030251, CG2145, [Score=102, Expect=7e-24]} {Celegans: WBGene00010488, endu-1, Poly(U)-specific endoribonuclease homolog, [Score=104, Expect=9e-26]} {Smed: dd_Smed_v6_9109_0_1, dd_Smed_v6_9109_0_1, [Score=98.6, Expect=6e-24]} {RNA1509_53582, RNA1509_5848} {RNA1310_25491.1, RNA1509_53582, RNA1509_5848} {RNA1509_53582, RNA1509_5848, RNA815_11062.1} |
14. | MligTC455_25456 | 316 | 6.58 | Mlig455_012134 | Neo: - Age: Up-Up-Down Region-enriched R4: 3.520/0.00139 |
ABCB1 | 0.959 | - | - | - | - | 0.959 | - | Mlig455_012134 {REF} {Length: 4685} {Pfam: ABC transporter transmembrane region [PF00664.25, score=428.2]; ABC transporter [PF00005.29, score=234.8]; RecF/RecN/SMC N terminal domain [PF02463.21, score=62.6]; AAA ATPase domain [PF13191.8, score=46.3]; Predicted ATPase of the ABC class [PF09818.11, score=32.1]; P-loop containing region of AAA domain [PF13555.8, score=30.3]; AAA domain [PF13401.8, score=29.3]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=29.0]; RsgA GTPase [PF03193.18, score=27.7]; AAA domain [PF13238.8, score=24.7]; AAA domain (dynein-related subfamily) [PF07728.16, score=24.1]; Rad17 P-loop domain [PF03215.17, score=22.6]; AAA domain [PF13481.8, score=20.7]; AAA domain [PF13521.8, score=20.7]; P-loop containing dynein motor region [PF12775.9, score=20.6]; Zeta toxin [PF06414.14, score=20.5]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=20.1]; Protein of unknown function (DUF815) [PF05673.15, score=19.7]; AAA domain [PF13604.8, score=19.2]; Cytidylate kinase [PF02224.20, score=18.5]} {Human: ENSG00000085563, ABCB1, ATP binding cassette subfamily B member 1, [Score=1137, Expect=0.0]; ENSG00000005471, ABCB4, ATP binding cassette subfamily B member 4, [Score=1100, Expect=0.0]} {Mouse: ENSMUSG00000040584, Abcb1a, ATP-binding cassette, sub-family B (MDR/TAP), member 1A, [Score=1137, Expect=0.0]; ENSMUSG00000028970, Abcb1b, ATP-binding cassette, sub-family B (MDR/TAP), member 1B, [Score=1123, Expect=0.0]; ENSMUSG00000042476, Abcb4, ATP-binding cassette, sub-family B (MDR/TAP), member 4, [Score=1093, Expect=0.0]} {Dmel: FBgn0004512, Mdr49, Multi drug resistance 49, [Score=822, Expect=0.0]} {Celegans: WBGene00004003, pgp-9, P-GlycoProtein related, [Score=1078, Expect=0.0]} {Smed: dd_Smed_v6_4124_0_1, dd_Smed_v6_4124_0_1, [Score=936, Expect=0.0]} {RNA1509_22046, RNA1509_2606} {RNA1310_1852.1, RNA1509_22046} {RNA1509_22046, RNA815_526.1} |