Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_36393 | 17515 | 364.89 | Mlig455_045161 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.767 Region-enriched R3: 2.754/0.00001 |
PROC | Mlig455_045161 {REF} {Length: 1434} {Pfam: Trypsin [PF00089.28, score=98.2]; Trypsin-like peptidase domain [PF13365.8, score=38.3]} {Human: ENSG00000115718, PROC, protein C, inactivator of coagulation factors Va and VIIIa, [Score=67.0, Expect=3e-12]} {Mouse: ENSMUSG00000024386, Proc, protein C, [Score=75.9, Expect=2e-15]; ENSMUSG00000034039, Prss29, protease, serine 29, [Score=73.6, Expect=4e-15]} {Dmel: FBgn0036738, CG7542, [Score=77.0, Expect=1e-16]} {Celegans: WBGene00006621, try-3, TRYpsin-like protease, [Score=48.1, Expect=1e-06]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [RH, Score=111, Expect=4e-30]} {RNA1509_18309, RNA1509_2871, RNA1509_29, RNA1509_44950, RNA1509_5544} {RNA1310_47138.1, RNA1509_18309, RNA1509_2871, RNA1509_44950, RNA1509_5544} {RNA1509_18309, RNA1509_2871, RNA1509_44950, RNA1509_5544, RNA815_8541.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.32 | 8.527 | 0.64683 | 1.00000 | |
RegionR2 | -2.641 | 8.527 | 0.00057 | 0.01478 | |
RegionR3 | 2.754 | 8.527 | 0.00000 | 0.00001 | |
RegionR4 | 2.294 | 8.527 | 0.00019 | 0.00269 | |
RegionR5 | 1.841 | 8.527 | 0.00038 | 0.00477 | |
RegionR6 | -0.108 | 8.527 | 0.86020 | 1.00000 | |
RegionR7 | -2.326 | 8.527 | 0.00130 | 0.04212 | |
RegionR8 | -1.494 | 8.527 | 0.03463 | 0.36518 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 0.901 | 8.527 | 0.26230 | 0.96879 | |
RegenerationR2 | 0.059 | 8.527 | 0.93665 | 1.00000 | |
RegenerationR3 | -0.991 | 8.527 | 0.20577 | 0.64092 | |
RegenerationR4 | -0.922 | 8.527 | 0.24821 | 0.69630 | |
RegenerationR5 | -0.784 | 8.527 | 0.31204 | 0.73749 | |
RegenerationR6 | -0.833 | 8.527 | 0.29875 | 0.64904 | |
RegenerationBL | -0.558 | 8.527 | 0.41860 | 0.78708 | |
RegenerationTP | 0.114 | 8.527 | 0.87229 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_36393 | 17515 | 364.89 | Mlig455_045161 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.767 Region-enriched R3: 2.754/0.00001 |
PROC | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_045161 {REF} {Length: 1434} {Pfam: Trypsin [PF00089.28, score=98.2]; Trypsin-like peptidase domain [PF13365.8, score=38.3]} {Human: ENSG00000115718, PROC, protein C, inactivator of coagulation factors Va and VIIIa, [Score=67.0, Expect=3e-12]} {Mouse: ENSMUSG00000024386, Proc, protein C, [Score=75.9, Expect=2e-15]; ENSMUSG00000034039, Prss29, protease, serine 29, [Score=73.6, Expect=4e-15]} {Dmel: FBgn0036738, CG7542, [Score=77.0, Expect=1e-16]} {Celegans: WBGene00006621, try-3, TRYpsin-like protease, [Score=48.1, Expect=1e-06]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [RH, Score=111, Expect=4e-30]} {RNA1509_18309, RNA1509_2871, RNA1509_29, RNA1509_44950, RNA1509_5544} {RNA1310_47138.1, RNA1509_18309, RNA1509_2871, RNA1509_44950, RNA1509_5544} {RNA1509_18309, RNA1509_2871, RNA1509_44950, RNA1509_5544, RNA815_8541.1} |
2. | MligTC455_27242 | 14489 | 301.86 | Mlig455_056957 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.849 Region-enriched R3: 2.848/0.00000 |
GM2A | 5.494 | 0.958 | 0.897 | 0.896 | 0.890 | 0.906 | 0.947 | Mlig455_056957 {REF} {Length: 877} {Pfam: ML domain [PF02221.17, score=41.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=51.6, Expect=7e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=50.8, Expect=1e-07]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=56.2, Expect=3e-10]} {RNA1509_960} {RNA1310_28835.1} {RNA815_6681.1} |
3. | MligTC455_51132 | 25223 | 525.48 | Mlig455_048208 | Neo: - Age: Down-Up-Up Region-enriched R3: 2.772/0.00000 |
5.29 | 0.966 | 0.925 | 0.831 | 0.968 | 0.872 | 0.728 | Mlig455_048208 {REF} {Length: 1734} {Pfam: Glycosyl hydrolases family 16 [PF00722.23, score=60.7]; Carbohydrate binding domain (family 32) [PF15886.7, score=40.4]} {Dmel: FBgn0040323, GNBP1, Gram-negative bacteria binding protein 1, [RH, Score=163, Expect=3e-44]} {RNA1509_1713, RNA1509_36676} {RNA1310_18175.1, RNA1509_1713, RNA1509_36676} {RNA1509_1713, RNA1509_36676, RNA815_10892.1} | |
4. | MligTC455_38477 | 31831 | 663.15 | Mlig455_025486, Mlig455_025508 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.748 Region-enriched R3: 3.522/0.00000 |
TMPRSS15 | 5.242 | 0.976 | 0.828 | 0.776 | 0.869 | 0.849 | 0.944 | Mlig455_025486 {REF} {Length: 1201} {Pfam: Trypsin [PF00089.28, score=254.3]; Trypsin-like peptidase domain [PF13365.8, score=38.5]; Domain of unknown function (DUF1986) [PF09342.13, score=34.2]} {Human: ENSG00000154646, TMPRSS15, transmembrane serine protease 15, [RH, Score=198, Expect=3e-57]; ENSG00000274058, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=194, Expect=4e-59]; ENSG00000087128, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=193, Expect=1e-58]; ENSG00000105707, HPN, hepsin, [RH, Score=191, Expect=9e-58]} {Mouse: ENSMUSG00000001249, Hpn, hepsin, [RH, Score=195, Expect=1e-59]; ENSMUSG00000030800, Prss8, protease, serine 8 (prostasin), [RH, Score=191, Expect=8e-59]} {Dmel: FBgn0051954, CG31954, [RH, Score=159, Expect=2e-47]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=164, Expect=4e-49]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=172, Expect=1e-48]} {RNA1509_237, RNA1509_4457} {RNA1310_26444, RNA1509_237, RNA1509_4457} {RNA1509_237, RNA1509_4457, RNA815_9945} Mlig455_025508 {REF} {Length: 1613} {Pfam: Trypsin [PF00089.28, score=254.3]; Trypsin-like peptidase domain [PF13365.8, score=38.5]; Domain of unknown function (DUF1986) [PF09342.13, score=34.2]} {Human: ENSG00000154646, TMPRSS15, transmembrane serine protease 15, [RH, Score=198, Expect=3e-57]; ENSG00000274058, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=194, Expect=4e-59]; ENSG00000087128, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=193, Expect=1e-58]; ENSG00000105707, HPN, hepsin, [RH, Score=191, Expect=9e-58]} {Mouse: ENSMUSG00000001249, Hpn, hepsin, [RH, Score=195, Expect=1e-59]; ENSMUSG00000030800, Prss8, protease, serine 8 (prostasin), [RH, Score=191, Expect=8e-59]} {Dmel: FBgn0051954, CG31954, [RH, Score=159, Expect=2e-47]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=164, Expect=4e-49]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=172, Expect=1e-48]} {RNA1509_237} {RNA1310_26444} {RNA815_9945} |
5. | MligTC455_36390 | 48194 | 1004.03 | Mlig455_045124, Mlig455_045158 | Neo: - Age: - Region-enriched R3: 1.884/0.01256 |
PRSS48 | 5.24 | 0.866 | 0.780 | 0.925 | 0.783 | 0.990 | 0.896 | Mlig455_045124 {REF} {Length: 909} {Pfam: Trypsin [PF00089.28, score=92.3]; Trypsin-like peptidase domain [PF13365.8, score=36.7]} {Human: ENSG00000189099, PRSS48, serine protease 48, [Score=57.8, Expect=2e-09]; ENSG00000141086, CTRL, chymotrypsin like, [Score=56.6, Expect=4e-09]; ENSG00000285141, PRSS55, serine protease 55, [Score=56.2, Expect=9e-09]; ENSG00000184647, PRSS55, serine protease 55, [Score=56.2, Expect=8e-09]} {Mouse: ENSMUSG00000024386, Proc, protein C, [Score=63.9, Expect=2e-11]; ENSMUSG00000034039, Prss29, protease, serine 29, [Score=62.8, Expect=2e-11]; ENSMUSG00000024171, Prss28, protease, serine 28, [Score=62.0, Expect=4e-11]} {Dmel: FBgn0036738, CG7542, [Score=81.3, Expect=4e-18]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [Score=107, Expect=2e-28]} {RNA1509_844} {RNA1310_53099} {RNA815_10800.1} Mlig455_045158 {REF} {Length: 908} {Pfam: Trypsin [PF00089.28, score=92.3]; Trypsin-like peptidase domain [PF13365.8, score=36.7]} {Human: ENSG00000189099, PRSS48, serine protease 48, [Score=57.8, Expect=2e-09]; ENSG00000141086, CTRL, chymotrypsin like, [Score=56.6, Expect=4e-09]; ENSG00000285141, PRSS55, serine protease 55, [Score=56.2, Expect=9e-09]; ENSG00000184647, PRSS55, serine protease 55, [Score=56.2, Expect=8e-09]} {Mouse: ENSMUSG00000024386, Proc, protein C, [Score=63.9, Expect=2e-11]; ENSMUSG00000034039, Prss29, protease, serine 29, [Score=62.8, Expect=2e-11]; ENSMUSG00000024171, Prss28, protease, serine 28, [Score=62.0, Expect=4e-11]} {Dmel: FBgn0036738, CG7542, [Score=81.3, Expect=4e-18]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [Score=107, Expect=2e-28]} {RNA1509_25483, RNA1509_30636, RNA1509_31656, RNA1509_38028, RNA1509_38124, RNA1509_5136, RNA1509_52862, RNA1509_535, RNA1509_633, RNA1509_8123, RNA1509_844} {RNA1310_53099, RNA1509_25483, RNA1509_30636, RNA1509_31656, RNA1509_38028, RNA1509_38124, RNA1509_5136, RNA1509_52862, RNA1509_535, RNA1509_633, RNA1509_8123, RNA1509_844} {RNA1509_25483, RNA1509_30636, RNA1509_31656, RNA1509_38028, RNA1509_38124, RNA1509_5136, RNA1509_52862, RNA1509_535, RNA1509_633, RNA1509_8123, RNA1509_844, RNA815_10800.1} |
6. | MligTC455_38482 | 16675 | 347.39 | Mlig455_035458, Mlig455_070530 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.639 Region-enriched R3: 3.465/0.00000 |
TMPRSS15 | 5.23 | 0.974 | 0.837 | 0.775 | 0.848 | 0.872 | 0.924 | Mlig455_035458 {REF} {Length: 302} {Pfam: Motilin/ghrelin-associated peptide [PF04643.14, score=20.2]} Mlig455_070530 {REF} {Length: 1350} {Pfam: Trypsin [PF00089.28, score=253.0]; Trypsin-like peptidase domain [PF13365.8, score=38.5]; Domain of unknown function (DUF1986) [PF09342.13, score=34.6]} {Human: ENSG00000154646, TMPRSS15, transmembrane serine protease 15, [RH, Score=195, Expect=3e-56]; ENSG00000087128, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=194, Expect=7e-59]; ENSG00000274058, TMPRSS11E, transmembrane serine protease 11E, [RH, Score=194, Expect=7e-59]; ENSG00000105707, HPN, hepsin, [RH, Score=189, Expect=5e-57]} {Mouse: ENSMUSG00000001249, Hpn, hepsin, [RH, Score=197, Expect=3e-60]; ENSMUSG00000030800, Prss8, protease, serine 8 (prostasin), [RH, Score=192, Expect=2e-59]} {Dmel: FBgn0051954, CG31954, [RH, Score=160, Expect=1e-47]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=164, Expect=3e-49]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=173, Expect=5e-49]} {RNA1509_237, RNA1509_33683} {RNA1310_26444, RNA1509_33683} {RNA1509_33683, RNA815_9945} |
7. | MligTC455_25767 | 22728 | 473.49 | Mlig455_011820 | Neo: - Age: - Region-enriched R3: 2.193/0.00049 |
5.201 | 0.921 | 0.859 | 0.945 | 0.776 | 0.982 | 0.718 | Mlig455_011820 {REF} {Length: 1886} {Pfam: Domain of unknown function (DUF758) [PF05527.13, score=45.6]; Family of unknown function (DUF6415) [PF19979.1, score=44.3]; Baculovirus polyhedron envelope protein, PEP, C terminus [PF04513.14, score=41.3]; Nucleopolyhedrovirus P10 protein [PF05531.14, score=39.8]; YtxH-like protein [PF12732.9, score=36.0]; Family of unknown function (DUF5856) [PF19174.2, score=28.6]; Protein of unknown function, DUF573 [PF04504.16, score=26.6]; Domain of unknown function (DUF4123) [PF13503.8, score=26.1]; Four helix bundle sensory module for signal transduction [PF12729.9, score=25.6]; Neuropeptide-like [PF15161.8, score=25.5]; Gypsy protein [PF07253.13, score=25.4]; Domain of unknown function (DUF4456) [PF14644.8, score=23.3]; Lambda phage tail tape-measure protein (Tape_meas_lam_C) [PF09718.12, score=22.7]; Domain of unknown function (DUF4142) [PF13628.8, score=22.3]; Type VI secretion system, TssO [PF17561.4, score=22.1]; Tsi6 [PF18660.3, score=21.8]; Domain of unknown function (DUF4795) [PF16043.7, score=21.5]; Protein of unknown function (DUF668) [PF05003.14, score=20.9]; Helix-turn-helix domain [PF13518.8, score=20.1]; MobL relaxases [PF18555.3, score=20.1]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.8]; Exonuclease VII, large subunit [PF02601.17, score=19.8]; Ku C terminal domain like [PF08785.13, score=19.8]; Tetratricopeptide repeat [PF14559.8, score=19.5]; UpxZ family of transcription anti-terminator antagonists [PF06603.13, score=19.2]; Protein of unknown function (DUF1722) [PF08349.13, score=19.2]; MnmE helical domain [PF12631.9, score=18.8]; Ubinuclein conserved middle domain [PF14075.8, score=18.6]} {Celegans: WBGene00000140, anc-1, Nuclear anchorage protein 1, [Score=51.6, Expect=1e-06]} {RNA1509_141, RNA1509_20385, RNA1509_21094, RNA1509_2517} {RNA1310_32826, RNA1509_20385, RNA1509_21094, RNA1509_2517} {RNA1509_20385, RNA1509_21094, RNA1509_2517, RNA815_5983.1} | |
8. | MligTC455_31554 | 12688 | 264.32 | Mlig455_003094 | Neo: - Age: Down-Up-Down Region-enriched R4: 2.454/0.01927 |
5.163 | 0.709 | 0.863 | 0.958 | 0.881 | 0.841 | 0.911 | Mlig455_003094 {REF} {Length: 2681} {Pfam: Wolframin Sel1-like repeat [PF20023.1, score=52.7]; Crp-like helix-turn-helix domain [PF13545.8, score=50.3]; 4'-phosphopantetheinyl transferase superfamily [PF01648.22, score=47.0]; Family of unknown function (DUF6307) [PF19826.1, score=42.0]; MarR family [PF01047.24, score=38.3]; Ribosomal protein L10 [PF00466.22, score=38.1]; Skp1 family, tetramerisation domain [PF03931.17, score=35.7]; PASTA domain [PF03793.21, score=32.0]; Family of unknown function (DUF6470) [PF20074.1, score=32.0]; D-lactate dehydrogenase, membrane binding [PF09330.13, score=30.1]; SprT-like family [PF10263.11, score=26.5]; winged helix-turn-helix [PF16221.7, score=26.3]; CUT domain [PF02376.17, score=24.1]; Helicase HerA, central domain [PF01935.19, score=22.5]; Bpu10I restriction endonuclease [PF09549.12, score=22.1]; von Willebrand factor type A domain [PF13768.8, score=21.6]; Protein of unknown function (DUF1340) [PF07067.13, score=21.0]; Mobile element transfer protein [PF05122.15, score=18.8]} {RNA1509_27680} {RNA1310_14862.1} {RNA815_5816} | |
9. | MligTC455_37228 | 6330 | 131.87 | Mlig455_000997, Mlig455_000998 | Neo: - Age: - Region-enriched R3: 3.678/0.00000 |
5.015 | 0.969 | 0.767 | 0.903 | 0.746 | 0.703 | 0.927 | Mlig455_000997 {REF} {Length: 1791} {NoTransDecoderORF} {RNA1509_48140} {RNA1310_37194} {RNA815_10967.1} Mlig455_000998 {REF} {Length: 1436} {NoTransDecoderORF} {RNA1509_55514} {RNA1310_37194} {RNA815_10967.1} |
|
10. | MligTC455_24831 | 29261 | 609.59 | Mlig455_026425 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=1.176 Region-enriched R3: 2.548/0.00001 |
GM2A | 4.629 | 0.937 | 0.907 | 0.890 | 0.953 | 0.942 | - | Mlig455_026425 {REF} {Length: 1161} {Pfam: ML domain [PF02221.17, score=45.7]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=62.0, Expect=3e-11]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=64.3, Expect=3e-12]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [RH, Score=89.4, Expect=4e-22]} {RNA1509_43, RNA1509_8277} {RNA1310_42438, RNA1509_43, RNA1509_8277} {RNA1509_43, RNA1509_8277, RNA815_22343} |
11. | MligTC455_24832 | 29294 | 610.29 | Mlig455_026454 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=1.350 Region-enriched R3: 2.547/0.00001 |
GM2A | 4.626 | 0.937 | 0.907 | 0.890 | 0.953 | 0.939 | - | Mlig455_026454 {REF} {Length: 1032} {Pfam: ML domain [PF02221.17, score=45.6]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=62.0, Expect=3e-11]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=64.3, Expect=3e-12]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [RH, Score=89.4, Expect=4e-22]} {RNA1509_8277} {RNA1310_42438} {RNA815_22343} |
12. | MligTC455_24833 | 29338 | 611.2 | Mlig455_044748 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.373 Region-enriched R3: 2.539/0.00001 |
GM2A | 4.624 | 0.937 | 0.907 | 0.887 | 0.952 | 0.941 | - | Mlig455_044748 {REF} {Length: 1032} {Pfam: ML domain [PF02221.17, score=45.6]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=62.0, Expect=3e-11]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=64.3, Expect=3e-12]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [RH, Score=89.4, Expect=4e-22]} {RNA1509_1066, RNA1509_8277} {RNA1310_42438, RNA1509_1066} {RNA1509_1066, RNA815_22343} |
13. | MligTC455_36391 | 24307 | 506.39 | Mlig455_045125, Mlig455_045159 | Neo: - Age: logFC(26M/2M)=-0.927 Region-enriched R3: 3.255/0.00000 |
PROC | 4.62 | 0.983 | 0.979 | 0.911 | - | 0.760 | 0.987 | Mlig455_045125 {REF} {Length: 929} {Pfam: Trypsin [PF00089.28, score=94.8]; Trypsin-like peptidase domain [PF13365.8, score=36.8]} {Human: ENSG00000115718, PROC, protein C, inactivator of coagulation factors Va and VIIIa, [Score=62.4, Expect=8e-11]; ENSG00000172236, TPSAB1, tryptase alpha/beta 1, [Score=59.3, Expect=4e-10]} {Mouse: ENSMUSG00000024386, Proc, protein C, [Score=70.9, Expect=8e-14]; ENSMUSG00000050063, Klk6, kallikrein related-peptidase 6, [Score=68.6, Expect=1e-13]} {Dmel: FBgn0036738, CG7542, [Score=80.1, Expect=1e-17]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [RH, Score=115, Expect=7e-32]} {RNA1509_15040, RNA1509_19320, RNA1509_2113, RNA1509_39015, RNA1509_39167, RNA1509_4268, RNA1509_49096, RNA1509_9437} {RNA1310_47138.1, RNA1509_15040, RNA1509_19320, RNA1509_2113, RNA1509_39015, RNA1509_39167, RNA1509_4268, RNA1509_49096, RNA1509_9437} {RNA1509_15040, RNA1509_19320, RNA1509_2113, RNA1509_39015, RNA1509_39167, RNA1509_4268, RNA1509_49096, RNA1509_9437, RNA815_8541.2} Mlig455_045159 {REF} {Length: 929} {Pfam: Trypsin [PF00089.28, score=94.8]; Trypsin-like peptidase domain [PF13365.8, score=36.8]} {Human: ENSG00000115718, PROC, protein C, inactivator of coagulation factors Va and VIIIa, [Score=62.4, Expect=8e-11]; ENSG00000172236, TPSAB1, tryptase alpha/beta 1, [Score=59.3, Expect=4e-10]} {Mouse: ENSMUSG00000024386, Proc, protein C, [Score=70.9, Expect=8e-14]; ENSMUSG00000050063, Klk6, kallikrein related-peptidase 6, [Score=68.6, Expect=1e-13]} {Dmel: FBgn0036738, CG7542, [Score=80.1, Expect=1e-17]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [RH, Score=115, Expect=7e-32]} {RNA1509_19320} {RNA1310_47138.1} {RNA815_8541.2} |
14. | MligTC455_51131 | 5808 | 120.99 | Mlig455_031629 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-0.484 Region-enriched R3: 3.757/0.00000 |
4.544 | 0.960 | 0.825 | 0.914 | 0.880 | - | 0.965 | Mlig455_031629 {REF} {Length: 1657} {Pfam: Glycosyl hydrolases family 16 [PF00722.23, score=60.4]} {Dmel: FBgn0040323, GNBP1, Gram-negative bacteria binding protein 1, [RH, Score=160, Expect=4e-44]} {RNA1509_304} {RNA1310_18175.2} {RNA815_10892.1} | |
15. | MligTC455_37186 | 4329 | 90.18 | Mlig455_049358 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.615 Region-enriched R3: 2.564/0.00000 |
4.543 | 0.970 | 0.962 | 0.938 | - | 0.733 | 0.940 | Mlig455_049358 {REF} {Length: 1834} {Pfam: QacR-like protein, C-terminal region [PF08360.13, score=18.9]} {RNA1509_252} {RNA1310_4046.2} {RNA815_6338.1} | |
16. | MligTC455_17786 | 5712 | 118.99 | Mlig455_018639 | Neo: - Age: logFC(26M/2M)=0.505 Region-enriched R3: 2.605/0.00046 |
4.525 | 0.964 | 0.974 | 0.876 | - | 0.808 | 0.903 | Mlig455_018639 {REF} {Length: 577} {RNA1509_4836} {RNA1310_1935.1} {RNA815_12746} | |
17. | MligTC455_39422 | 15237 | 317.44 | Mlig455_038446, Mlig455_038587 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=-0.458 Region-enriched R3: 3.133/0.00000 |
MRC1 | 4.501 | 0.970 | 0.969 | 0.894 | 0.713 | - | 0.955 | Mlig455_038446 {REF} {Length: 1218} {Pfam: Lectin C-type domain [PF00059.23, score=95.6]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=37.9]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [Score=77.8, Expect=5e-15]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=58.5, Expect=7e-09]; ENSMUSG00000020695, Mrc2, mannose receptor, C type 2, [Score=58.2, Expect=7e-09]; ENSMUSG00000020884, Asgr1, asialoglycoprotein receptor 1, [Score=57.4, Expect=4e-09]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [Score=58.2, Expect=2e-09]} {Smed: dd_Smed_v6_1489_0_1, dd_Smed_v6_1489_0_1, [Score=51.6, Expect=2e-07]} {RNA1509_980} {RNA1310_5522.1} {RNA815_4429} Mlig455_038587 {REF} {Length: 1225} {Pfam: Lectin C-type domain [PF00059.23, score=93.7]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=39.2]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [Score=74.3, Expect=7e-14]} {Mouse: ENSMUSG00000020695, Mrc2, mannose receptor, C type 2, [Score=60.1, Expect=2e-09]; ENSMUSG00000020884, Asgr1, asialoglycoprotein receptor 1, [Score=58.2, Expect=3e-09]; ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=57.4, Expect=1e-08]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [Score=54.3, Expect=4e-08]} {Smed: dd_Smed_v6_1489_0_1, dd_Smed_v6_1489_0_1, [Score=51.2, Expect=4e-07]} {RNA1509_13839, RNA1509_25500, RNA1509_980} {RNA1310_5522.1, RNA1509_13839, RNA1509_25500} {RNA1509_13839, RNA1509_25500, RNA815_4429} |
18. | MligTC455_28661 | 1197 | 24.95 | Mlig455_003667 | Neo: - Age: logFC(26M/2M)=0.386 Region-enriched R3: 3.225/0.00000 |
4.314 | 0.953 | 0.795 | 0.755 | 0.908 | - | 0.903 | Mlig455_003667 {REF} {Length: 2846} {RNA1509_11217, RNA1509_19513, RNA1509_20197} {RNA1310_24401, RNA1509_11217, RNA1509_19513, RNA1509_20197} {RNA1509_11217, RNA1509_19513, RNA1509_20197, RNA815_10016} | |
19. | MligTC455_36081 | 1387 | 28.89 | Mlig455_040332 | Neo: - Age: Down-Down-Down, logFC(26M/2M)=-0.740 Region-enriched R3: 3.050/0.00000 |
4.211 | 0.840 | 0.760 | 0.787 | 0.970 | - | 0.854 | Mlig455_040332 {REF} {Length: 2953} {Pfam: Transforming growth factor beta like domain [PF00019.22, score=44.8]} {RNA1509_5434} {RNA1310_5336} {RNA815_1739.1} | |
20. | MligTC455_22632 | 17908 | 373.08 | Mlig455_056621 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=1.479 Region-enriched R3: 3.047/0.00000 |
TMPRSS9 | 4.078 | 0.820 | 0.818 | 0.764 | 0.724 | - | 0.952 | Mlig455_056621 {REF} {Length: 1688} {Pfam: Trypsin [PF00089.28, score=252.4]; CUB domain [PF00431.22, score=105.1]; Low-density lipoprotein receptor domain class A [PF00057.20, score=46.9]; Trypsin-like peptidase domain [PF13365.8, score=33.6]; Domain of unknown function (DUF1986) [PF09342.13, score=28.8]} {Human: ENSG00000178297, TMPRSS9, transmembrane serine protease 9, [RH, Score=218, Expect=1e-62]; ENSG00000122194, PLG, plasminogen, [RH, Score=216, Expect=5e-62]; ENSG00000187950, OVCH1, ovochymase 1, [RH, Score=210, Expect=3e-59]; ENSG00000149418, ST14, suppression of tumorigenicity 14, [RH, Score=209, Expect=1e-59]} {Mouse: ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [RH, Score=216, Expect=1e-61]; ENSMUSG00000031995, St14, suppression of tumorigenicity 14 (colon carcinoma), [RH, Score=213, Expect=7e-61]} {Dmel: FBgn0033192, Corin, [RH, Score=182, Expect=5e-50]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=166, Expect=7e-48]} {Smed: dd_Smed_v6_2492_0_1, dd_Smed_v6_2492_0_1, [Score=167, Expect=5e-48]} {RNA1509_254} {RNA1310_22739.1} {RNA815_6357.1} |
21. | MligTC455_37187 | 7422 | 154.63 | Mlig455_062308 | Neo: - Age: Up-Down-Up, logFC(26M/2M)=0.525 Region-enriched R3: 2.316/0.00013 |
3.814 | 0.967 | 0.958 | 0.957 | - | - | 0.932 | Mlig455_062308 {REF} {Length: 1837} {Pfam: QacR-like protein, C-terminal region [PF08360.13, score=18.9]} {RNA1509_252, RNA1509_46852} {RNA1310_4046.2, RNA1509_252, RNA1509_46852} {RNA1509_252, RNA1509_46852, RNA815_6338.1} | |
22. | MligTC455_43194 | 11396 | 237.42 | Mlig455_009763, Mlig455_070122 | Neo: - Age: Down-Down-Up Region-enriched R3: 2.399/0.00716 |
CST3 | 3.678 | 0.984 | 0.848 | 0.935 | - | - | 0.911 | Mlig455_009763 {REF} {Length: 720} {Pfam: Cystatin domain [PF00031.23, score=28.8]} {Human: ENSG00000101439, CST3, cystatin C, [RH, Score=44.7, Expect=6e-06]} {RNA1509_26463, RNA1509_2883, RNA1509_6502} {RNA1310_51190, RNA1509_2883, RNA1509_6502} {RNA1509_2883, RNA1509_6502, RNA815_25269} Mlig455_070122 {REF} {Length: 736} {Pfam: Cystatin domain [PF00031.23, score=28.8]} {Human: ENSG00000101439, CST3, cystatin C, [RH, Score=44.7, Expect=6e-06]} {RNA1509_26463, RNA1509_4516, RNA1509_5046, RNA1509_7022} {RNA1310_51190, RNA1509_26463, RNA1509_4516, RNA1509_5046, RNA1509_7022} {RNA1509_26463, RNA1509_4516, RNA1509_5046, RNA1509_7022, RNA815_25269} |
23. | MligTC455_33965 | 17062 | 355.46 | Mlig455_057693 | Neo: - Age: logFC(26M/2M)=-0.368 Region-enriched R3: 3.675/0.00000 |
3.575 | 0.953 | 0.819 | - | 0.851 | - | 0.952 | Mlig455_057693 {REF} {Length: 618} {Pfam: Destabilase [PF05497.14, score=88.9]} {Dmel: FBgn0025827, CG6421, [Score=46.2, Expect=1e-06]} {Celegans: WBGene00016670, ilys-3, Invertebrate-type lysozyme 3, [Score=80.5, Expect=7e-20]} {RNA1509_25524} {RNA1310_5040} {RNA815_13101.2} | |
24. | MligTC455_33964 | 17054 | 355.3 | Mlig455_057690 | Neo: - Age: - Region-enriched R3: 3.681/0.00000 |
3.573 | 0.953 | 0.817 | - | 0.851 | - | 0.952 | Mlig455_057690 {REF} {Length: 582} {Pfam: Destabilase [PF05497.14, score=88.9]} {Dmel: FBgn0025827, CG6421, [Score=46.2, Expect=1e-06]} {Celegans: WBGene00016670, ilys-3, Invertebrate-type lysozyme 3, [Score=80.5, Expect=7e-20]} {RNA1509_25524} {RNA1310_5040} {RNA815_13101.1} | |
25. | MligTC455_56966 | 130 | 2.71 | Mlig455_033002 | Neo: - Age: - Region-enriched R3: 3.605/0.00022 |
3.544 | 0.969 | 0.867 | - | - | 0.871 | 0.837 | Mlig455_033002 {REF} {Length: 78} {NoTransDecoderORF} {RNA1509_7667} {RNA1310_50600} {RNA815_52664} | |
26. | MligTC455_36082 | 1063 | 22.14 | Mlig455_040337 | Neo: - Age: logFC(26M/2M)=-0.499 Region-enriched R4: 3.060/0.00000 |
3.504 | 0.806 | - | 0.871 | 0.964 | - | 0.863 | Mlig455_040337 {REF} {Length: 3101} {Pfam: Transforming growth factor beta like domain [PF00019.22, score=47.9]} {RNA1509_22478, RNA1509_5434} {RNA1310_5336, RNA1509_22478} {RNA1509_22478, RNA815_1739.1} | |
27. | MligTC455_47182 | 14582 | 303.8 | Mlig455_058015, Mlig455_058180, Mlig455_058206 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.558 Region-enriched R3: 3.886/0.00000 |
GM2A | 3.48 | 0.953 | 0.849 | 0.794 | - | - | 0.884 | Mlig455_058015 {REF} {Length: 1913} {Pfam: ML domain [PF02221.17, score=41.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=52.0, Expect=4e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=53.9, Expect=6e-09]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=73.9, Expect=6e-17]} {RNA1509_4247} {RNA1310_43150} {RNA815_23642.1} Mlig455_058180 {REF} {Length: 1416} {Pfam: ML domain [PF02221.17, score=41.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=52.0, Expect=4e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=53.9, Expect=6e-09]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=73.9, Expect=6e-17]} {RNA1509_4247} {RNA1310_43150} {RNA815_23642.1} Mlig455_058206 {REF} {Length: 1589} {Pfam: ML domain [PF02221.17, score=41.0]} {Human: ENSG00000196743, GM2A, GM2 ganglioside activator, [Score=52.0, Expect=4e-08]} {Mouse: ENSMUSG00000000594, Gm2a, GM2 ganglioside activator protein, [Score=53.9, Expect=6e-09]} {Smed: dd_Smed_v6_214_1_1, dd_Smed_v6_214_1_1, [Score=73.9, Expect=6e-17]} {RNA1509_3837, RNA1509_4247, RNA1509_4841, RNA1509_5347} {RNA1310_43150, RNA1509_3837, RNA1509_4247, RNA1509_4841, RNA1509_5347} {RNA1509_3837, RNA1509_4247, RNA1509_4841, RNA1509_5347, RNA815_23642.1} |
28. | MligTC455_52855 | 748 | 15.59 | Mlig455_029551, Mlig455_040460 | Neo: - Age: - Region-enriched R3: 5.112/0.00000 |
MCFD2 | 3.454 | 0.959 | 0.844 | 0.740 | - | - | 0.911 | Mlig455_029551 {REF} {Length: 937} {Pfam: EF-hand domain pair [PF13499.8, score=45.6]; EF-hand domain [PF13405.8, score=36.2]; EF hand [PF00036.34, score=36.1]; EF-hand domain pair [PF13833.8, score=25.7]} {Human: ENSG00000180398, MCFD2, multiple coagulation factor deficiency 2, [Score=62.0, Expect=5e-12]} {Mouse: ENSMUSG00000024150, Mcfd2, multiple coagulation factor deficiency 2, [Score=60.1, Expect=2e-11]} {Dmel: FBgn0037798, CG12817, [RH, Score=53.5, Expect=6e-09]} {Celegans: WBGene00010075, F55A11.1, [RH, Score=70.1, Expect=3e-15]} {RNA1509_28625} {RNA1310_37099} {RNA815_18915} Mlig455_040460 {REF} {Length: 1066} {Pfam: EF-hand domain pair [PF13499.8, score=41.5]; EF hand [PF00036.34, score=36.3]; EF-hand domain [PF13405.8, score=36.3]; EF-hand domain pair [PF13833.8, score=25.9]} {Human: ENSG00000180398, MCFD2, multiple coagulation factor deficiency 2, [Score=61.6, Expect=6e-12]} {Mouse: ENSMUSG00000024150, Mcfd2, multiple coagulation factor deficiency 2, [Score=60.1, Expect=1e-11]} {Dmel: FBgn0037798, CG12817, [RH, Score=53.5, Expect=4e-09]} {Celegans: WBGene00010075, F55A11.1, [RH, Score=70.1, Expect=2e-15]} {RNA1509_11624, RNA1509_17013, RNA1509_28625} {RNA1310_37099, RNA1509_11624, RNA1509_17013, RNA1509_28625} {RNA1509_11624, RNA1509_17013, RNA1509_28625, RNA815_18915} |
29. | MligTC455_15093 | 112 | 2.34 | Mlig455_041676 | Neo: - Age: - Region-enriched R3: 3.670/0.00011 |
3.417 | 0.957 | 0.847 | - | - | 0.755 | 0.858 | Mlig455_041676 {REF} {Length: 286} {NoTransDecoderORF} {RNA1509_45649} {RNA1310_103992} {RNA815_10967.1} | |
30. | MligTC455_22631 | 17842 | 371.71 | Mlig455_007773 | Neo: - Age: Up-Up-Up, logFC(26M/2M)=0.952 Region-enriched R3: 3.041/0.00000 |
TMPRSS9 | 3.353 | 0.820 | 0.818 | 0.764 | - | - | 0.951 | Mlig455_007773 {REF} {Length: 1686} {Pfam: Trypsin [PF00089.28, score=249.9]; CUB domain [PF00431.22, score=105.1]; Low-density lipoprotein receptor domain class A [PF00057.20, score=46.9]; Trypsin-like peptidase domain [PF13365.8, score=33.1]; Domain of unknown function (DUF1986) [PF09342.13, score=27.4]} {Human: ENSG00000178297, TMPRSS9, transmembrane serine protease 9, [RH, Score=218, Expect=9e-63]; ENSG00000122194, PLG, plasminogen, [RH, Score=211, Expect=1e-60]; ENSG00000149418, ST14, suppression of tumorigenicity 14, [RH, Score=208, Expect=3e-59]} {Mouse: ENSMUSG00000059406, Tmprss9, transmembrane protease, serine 9, [RH, Score=217, Expect=1e-61]; ENSMUSG00000031995, St14, suppression of tumorigenicity 14 (colon carcinoma), [RH, Score=211, Expect=2e-60]; ENSMUSG00000016942, Tmprss6, transmembrane serine protease 6, [RH, Score=209, Expect=1e-59]} {Dmel: FBgn0033192, Corin, [RH, Score=184, Expect=1e-50]} {Celegans: WBGene00006619, try-1, TRYpsin-like protease, [RH, Score=165, Expect=9e-48]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=175, Expect=1e-47]} {RNA1509_10189, RNA1509_254, RNA1509_423, RNA1509_8940} {RNA1310_22739.1, RNA1509_10189, RNA1509_254, RNA1509_423, RNA1509_8940} {RNA1509_10189, RNA1509_254, RNA1509_423, RNA1509_8940, RNA815_6357.1} |
31. | MligTC455_36392 | 39001 | 812.51 | Mlig455_045127 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.250 Region-enriched R3: 1.703/0.00504 |
PROC | 2.788 | - | - | 0.948 | 0.996 | 0.844 | - | Mlig455_045127 {REF} {Length: 860} {Pfam: Trypsin [PF00089.28, score=97.2]; Trypsin-like peptidase domain [PF13365.8, score=38.2]} {Human: ENSG00000115718, PROC, protein C, inactivator of coagulation factors Va and VIIIa, [Score=66.2, Expect=4e-12]} {Mouse: ENSMUSG00000024386, Proc, protein C, [Score=75.5, Expect=2e-15]; ENSMUSG00000034039, Prss29, protease, serine 29, [Score=73.6, Expect=4e-15]} {Dmel: FBgn0036738, CG7542, [Score=77.0, Expect=1e-16]} {Celegans: WBGene00006621, try-3, TRYpsin-like protease, [Score=48.9, Expect=6e-07]} {Smed: dd_Smed_v6_10973_0_2, dd_Smed_v6_10973_0_2, [RH, Score=112, Expect=2e-30]} {RNA1509_29, RNA1509_30952, RNA1509_45912} {RNA1310_47138.1, RNA1509_29, RNA1509_30952, RNA1509_45912} {RNA1509_29, RNA1509_30952, RNA1509_45912, RNA815_8541.1} |
32. | MligTC455_44096 | 32 | 0.67 | Mlig455_018761, Mlig455_018927 | Neo: - Age: - Region-enriched R4: 5.939/0.00142 |
2.454 | - | 0.760 | - | - | 0.954 | 0.740 | Mlig455_018761 {REF} {Length: 1605} {RNA1509_36146} {RNA1310_50474} {RNA815_9284} Mlig455_018927 {REF} {Length: 238} {NoTransDecoderORF} |