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Results for MligTC455_22683

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_22683 1080 22.51 Mlig455_006288

Neo: -

Age: Down-Up-Down

PDE8A Mlig455_006288 {REF} {Length: 3418} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=283.6]; PAS domain [PF13426.9, score=37.0]; PAS fold [PF08447.14, score=36.0]; PAS fold [PF00989.27, score=28.3]; PAS fold [PF08448.12, score=28.0]} {Human: ENSG00000073417, PDE8A, phosphodiesterase 8A, [Score=561, Expect=0.0]; ENSG00000113231, PDE8B, phosphodiesterase 8B, [Score=554, Expect=0.0]; ENSG00000284762, AC022414.1, phosphodiesterase 8B, [Score=553, Expect=0.0]} {Mouse: ENSMUSG00000021684, Pde8b, phosphodiesterase 8B, [Score=557, Expect=0.0]; ENSMUSG00000025584, Pde8a, phosphodiesterase 8A, [Score=545, Expect=0.0]} {Dmel: FBgn0266377, Pde8, Phosphodiesterase 8, [Score=388, Expect=4e-124]} {Celegans: WBGene00022389, pde-6, Probable 3',5'-cyclic phosphodiesterase pde-6, [RH, Score=306, Expect=1e-93]} {Smed: dd_Smed_v6_10593_0_1, dd_Smed_v6_10593_0_1, [RH, Score=454, Expect=2e-149]} {RNA1509_1517} {RNA1310_2301} {RNA815_483.1}

Cumulative graph for MligTC455_22683

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.883 4.697 0.30114 0.95096
RegionR2 0.536 4.697 0.09408 0.37611
RegionR3 0.43 4.697 0.09521 0.54236
RegionR4 -0.065 4.697 0.83022 1.00000
RegionR5 0.52 4.697 0.02502 0.11368
RegionR6 0.193 4.697 0.48605 1.00000
RegionR7 -0.214 4.697 0.58596 1.00000
RegionR8 -0.517 4.697 0.32011 0.95407

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.604 4.697 0.58970 1.00000
RegenerationR2 0.463 4.697 0.03565 0.31173
RegenerationR3 -0.115 4.697 0.66046 0.93337
RegenerationR4 -0.25 4.697 0.37084 0.79452
RegenerationR5 -0.309 4.697 0.19544 0.62707
RegenerationR6 -0.519 4.697 0.08065 0.35462
RegenerationBL -0.042 4.697 0.91629 1.00000
RegenerationTP -0.059 4.697 0.89781 1.00000


Genes with expression patterns similar to MligTC455_22683

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_22683 1080 22.51 Mlig455_006288

Neo: -

Age: Down-Up-Down

PDE8A 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_006288 {REF} {Length: 3418} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=283.6]; PAS domain [PF13426.9, score=37.0]; PAS fold [PF08447.14, score=36.0]; PAS fold [PF00989.27, score=28.3]; PAS fold [PF08448.12, score=28.0]} {Human: ENSG00000073417, PDE8A, phosphodiesterase 8A, [Score=561, Expect=0.0]; ENSG00000113231, PDE8B, phosphodiesterase 8B, [Score=554, Expect=0.0]; ENSG00000284762, AC022414.1, phosphodiesterase 8B, [Score=553, Expect=0.0]} {Mouse: ENSMUSG00000021684, Pde8b, phosphodiesterase 8B, [Score=557, Expect=0.0]; ENSMUSG00000025584, Pde8a, phosphodiesterase 8A, [Score=545, Expect=0.0]} {Dmel: FBgn0266377, Pde8, Phosphodiesterase 8, [Score=388, Expect=4e-124]} {Celegans: WBGene00022389, pde-6, Probable 3',5'-cyclic phosphodiesterase pde-6, [RH, Score=306, Expect=1e-93]} {Smed: dd_Smed_v6_10593_0_1, dd_Smed_v6_10593_0_1, [RH, Score=454, Expect=2e-149]} {RNA1509_1517} {RNA1310_2301} {RNA815_483.1}
2. MligTC455_22682 782 16.28 Mlig455_006226

Neo: -

Age: Down-Up-Down

PDE8B 2.771 - - 0.851 0.971 0.949 - Mlig455_006226 {REF} {Length: 5356} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=282.4]; PAS domain [PF13426.9, score=46.9]; PAS fold [PF08448.12, score=37.2]; PAS fold [PF08447.14, score=35.4]; PAS fold [PF00989.27, score=34.8]} {Human: ENSG00000113231, PDE8B, phosphodiesterase 8B, [RH, Score=655, Expect=0.0]; ENSG00000284762, AC022414.1, phosphodiesterase 8B, [RH, Score=654, Expect=0.0]; ENSG00000073417, PDE8A, phosphodiesterase 8A, [RH, Score=641, Expect=0.0]} {Mouse: ENSMUSG00000021684, Pde8b, phosphodiesterase 8B, [RH, Score=659, Expect=0.0]} {Dmel: FBgn0266377, Pde8, Phosphodiesterase 8, [RH, Score=442, Expect=1e-142]} {Celegans: WBGene00022389, pde-6, Probable 3',5'-cyclic phosphodiesterase pde-6, [RH, Score=307, Expect=2e-92]} {Smed: dd_Smed_v6_10593_0_1, dd_Smed_v6_10593_0_1, [RH, Score=474, Expect=5e-155]} {RNA1509_36096, RNA1509_44408, RNA1509_54068} {RNA1310_2301, RNA1509_44408, RNA1509_54068} {RNA1509_44408, RNA1509_54068, RNA815_483.1}
3. MligTC455_43525 62 1.29 Mlig455_041078

Neo: -

Age: -

2.573 - - - 0.868 0.951 0.754 Mlig455_041078 {REF} {Length: 3896} {RNA1509_39963} {RNA1310_38466} {RNA815_23614}
4. MligTC455_47103 969 20.19 Mlig455_026719, Mlig455_051709

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.266

2.528 - - - 0.819 0.950 0.759

Mlig455_026719 {REF} {Length: 2148} {TRANSSPLICED} {Pfam: Testis-specific gene 13 protein [PF14994.8, score=19.3]} {RNA1509_13708, RNA1509_55368} {RNA1310_11676, RNA1509_55368} {RNA1509_55368, RNA815_4230}

Mlig455_051709 {REF} {Length: 2150} {TRANSSPLICED} {Pfam: Testis-specific gene 13 protein [PF14994.8, score=19.1]} {RNA1509_13708} {RNA1310_11676, RNA1509_13708} {RNA1509_13708, RNA815_4230}
5. MligTC455_49394 1184 24.68 Mlig455_041577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.255/0.02823

2.469 - - - 0.966 0.751 0.752 Mlig455_041577 {REF} {Length: 928} {Pfam: Normal lung function maintenance, Low in Lung Cancer 1 protein [PF14945.8, score=24.7]} {Smed: dd_Smed_v6_6024_0_1, dd_Smed_v6_6024_0_1, [Score=97.8, Expect=1e-26]} {RNA1509_17780, RNA1509_38038} {RNA1310_47454, RNA1509_17780, RNA1509_38038} {RNA1509_17780, RNA1509_38038, RNA815_24792.1}
6. MligTC455_44157 2728 56.84 Mlig455_015483

Neo: -

Age: logFC(26M/2M)=-0.621

Region-enriched R4: 1.377/0.00397

SPAG8 2.406 - - 0.725 0.955 0.726 - Mlig455_015483 {REF} {Length: 1025} {Human: ENSG00000137098, SPAG8, sperm associated antigen 8, [RH, Score=83.2, Expect=3e-18]} {Mouse: ENSMUSG00000066196, Spag8, sperm associated antigen 8, [RH, Score=90.9, Expect=4e-21]} {Smed: dd_Smed_v6_6123_0_1, dd_Smed_v6_6123_0_1, [RH, Score=131, Expect=1e-38]} {RNA1509_3548} {RNA1310_4106} {RNA815_16577}
7. MligTC455_42746 483 10.06 Mlig455_040721

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.368

ACSF2 1.89 - - - 0.961 0.929 - Mlig455_040721 {REF} {Length: 3197} {Pfam: AMP-binding enzyme [PF00501.30, score=314.2]; AMP-binding enzyme C-terminal domain [PF13193.8, score=37.2]} {Human: ENSG00000167107, ACSF2, acyl-CoA synthetase family member 2, [Score=147, Expect=1e-37]} {Mouse: ENSMUSG00000076435, Acsf2, acyl-CoA synthetase family member 2, [Score=156, Expect=8e-41]} {Dmel: FBgn0027601, pdgy, pudgy, [Score=269, Expect=8e-83]} {Celegans: WBGene00008669, acs-14, Fatty Acid CoA Synthetase family, [Score=259, Expect=1e-79]} {Smed: dd_Smed_v6_10135_0_1, dd_Smed_v6_10135_0_1, [Score=317, Expect=5e-102]} {RNA1509_22715} {RNA1310_10057.2} {RNA815_14069}
8. MligTC455_33852 833 17.35 Mlig455_009849, Mlig455_029790

Neo: -

Age: Down-Up-Down

Region-enriched R2: 2.367/0.00015
Region-enriched R3: 1.279/0.02717

MGAT1, SLC24A3 1.87 - - - 0.901 0.969 -

Mlig455_009849 {REF} {Length: 3524} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=160.6]} {Human: ENSG00000185052, SLC24A3, solute carrier family 24 member 3, [Score=173, Expect=5e-45]; ENSG00000155886, SLC24A2, solute carrier family 24 member 2, [Score=172, Expect=2e-44]; ENSG00000140090, SLC24A4, solute carrier family 24 member 4, [Score=172, Expect=8e-45]} {Mouse: ENSMUSG00000041771, Slc24a4, solute carrier family 24 (sodium/potassium/calcium exchanger), member 4, [Score=171, Expect=6e-45]; ENSMUSG00000063873, Slc24a3, solute carrier family 24 (sodium/potassium/calcium exchanger), member 3, [Score=171, Expect=1e-44]; ENSMUSG00000037996, Slc24a2, solute carrier family 24 (sodium/potassium/calcium exchanger), member 2, [Score=170, Expect=6e-44]} {Dmel: FBgn0028704, Nckx30C, [Score=163, Expect=4e-41]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=143, Expect=2e-35]} {Smed: dd_Smed_v6_9736_0_1, dd_Smed_v6_9736_0_1, [Score=310, Expect=2e-95]} {RNA1509_4329} {RNA1310_8845} {RNA815_2786.1}

Mlig455_029790 {REF} {Length: 1524} {Pfam: GNT-I family [PF03071.17, score=204.9]} {Human: ENSG00000131446, MGAT1, mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, [Score=152, Expect=5e-41]} {Mouse: ENSMUSG00000020346, Mgat1, mannoside acetylglucosaminyltransferase 1, [Score=166, Expect=3e-46]} {Dmel: FBgn0034521, Mgat1, Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1, [Score=171, Expect=2e-48]} {Celegans: WBGene00001638, gly-13, Putative alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, [Score=145, Expect=1e-38]} {Smed: dd_Smed_v6_13024_0_1, dd_Smed_v6_13024_0_1, [Score=156, Expect=3e-43]} {RNA1310_114996}
9. MligTC455_29040 262 5.46 Mlig455_003133

Neo: -

Age: Down-Up-Down

VWA3B 1.832 - - - 0.876 0.956 - Mlig455_003133 {REF} {Length: 4304} {TRANSSPLICED} {Pfam: von Willebrand factor type A domain [PF13768.8, score=82.5]; von Willebrand factor type A domain [PF00092.30, score=41.8]; von Willebrand factor type A domain [PF13519.8, score=31.6]} {Human: ENSG00000168658, VWA3B, von Willebrand factor A domain containing 3B, [RH, Score=608, Expect=0.0]} {Mouse: ENSMUSG00000050122, Vwa3b, von Willebrand factor A domain containing 3B, [RH, Score=446, Expect=2e-141]} {Smed: dd_Smed_v6_9363_0_2, dd_Smed_v6_9363_0_2, [RH, Score=928, Expect=0.0]} {RNA1509_3581} {RNA1310_1567} {RNA815_329.1}
10. MligTC455_19337 1925 40.11 Mlig455_019013, Mlig455_055690

Neo: -

Age: -

FAT4 1.831 - - - 0.863 0.968 -

Mlig455_019013 {REF} {Length: 5843} {Pfam: Cadherin domain [PF00028.19, score=416.2]; Cadherin-like [PF16184.7, score=51.1]; Cadherin-like [PF08266.14, score=37.4]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=337, Expect=8e-93]; ENSG00000107736, CDH23, cadherin related 23, [Score=323, Expect=3e-88]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=340, Expect=7e-94]} {Dmel: FBgn0037963, Cad87A, Cadherin 87A, [RH, Score=565, Expect=1e-169]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=224, Expect=2e-58]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=285, Expect=1e-77]} {RNA1509_10894, RNA1509_28143} {RNA1310_769, RNA1509_10894, RNA1509_28143} {RNA1509_10894, RNA1509_28143, RNA815_221.1}

Mlig455_055690 {REF} {Length: 5861} {Pfam: Cadherin domain [PF00028.19, score=416.3]; Cadherin-like [PF16184.7, score=51.2]; Cadherin-like [PF08266.14, score=37.1]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=339, Expect=2e-93]; ENSG00000107736, CDH23, cadherin related 23, [Score=328, Expect=8e-90]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=345, Expect=3e-95]} {Dmel: FBgn0037963, Cad87A, Cadherin 87A, [RH, Score=561, Expect=2e-168]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=221, Expect=1e-57]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=278, Expect=3e-75]} {RNA1509_28056, RNA1509_38617, RNA1509_4473} {RNA1310_769, RNA1509_28056, RNA1509_38617, RNA1509_4473} {RNA1509_28056, RNA1509_38617, RNA1509_4473, RNA815_221.1}
11. MligTC455_34559 580 12.07 Mlig455_066815

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.459

GSTA2 1.824 - - - 0.969 - 0.855 Mlig455_066815 {REF} {Length: 1741} {Pfam: Glutathione S-transferase, N-terminal domain [PF02798.22, score=40.7]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=27.2]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=27.1]} {Human: ENSG00000244067, GSTA2, glutathione S-transferase alpha 2, [Score=66.6, Expect=8e-13]; ENSG00000243955, GSTA1, glutathione S-transferase alpha 1, [Score=64.7, Expect=3e-12]} {Mouse: ENSMUSG00000032348, Gsta4, glutathione S-transferase, alpha 4, [RH, Score=58.9, Expect=4e-11]} {Dmel: FBgn0010226, GstS1, Glutathione S transferase S1, [Score=66.6, Expect=5e-13]} {Celegans: WBGene00001786, gst-38, Glutathione S-Transferase, [Score=65.1, Expect=8e-13]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=95.1, Expect=3e-24]} {RNA1509_50934} {RNA1310_26310, RNA1509_50934} {RNA1509_50934, RNA815_40328}
12. MligTC455_23082 1608 33.5 Mlig455_024173

Neo: -

Age: -

FAT4 1.811 - - - 0.959 0.852 - Mlig455_024173 {REF} {Length: 8284} {Pfam: Cadherin domain [PF00028.19, score=731.9]; Cadherin-like [PF16184.7, score=111.8]; Cadherin-like [PF08266.14, score=26.5]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=544, Expect=2e-155]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=514, Expect=2e-146]} {Dmel: FBgn0284247, ds, dachsous, [Score=463, Expect=8e-131]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=276, Expect=4e-74]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=279, Expect=7e-75]} {RNA1509_848} {RNA1310_296} {RNA815_105}
13. MligTC455_24829 258 5.39 Mlig455_001260

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.723

CCDC80 1.811 - - - 0.956 0.855 - Mlig455_001260 {REF} {Length: 10454} {Human: ENSG00000091986, CCDC80, coiled-coil domain containing 80, [Score=52.8, Expect=1e-05]} {Dmel: FBgn0053196, dpy, dumpy, [Score=52.4, Expect=9e-06]} {RNA1509_23601} {RNA1310_241} {RNA815_110.1}
14. MligTC455_15662 187 3.89 Mlig455_030386

Neo: -

Age: -

Region-enriched R2: 3.832/0.01388

Regeneration-upregulated BL: 4.705

Regeneration-enriched BL: 4.705

NR2E1 1.784 - - - 0.830 0.954 - Mlig455_030386 {REF} {Length: 2439} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=98.4]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=73.9]} {Human: ENSG00000112333, NR2E1, nuclear receptor subfamily 2 group E member 1, [RH, Score=190, Expect=8e-54]} {Mouse: ENSMUSG00000019803, Nr2e1, nuclear receptor subfamily 2, group E, member 1, [Score=190, Expect=2e-54]} {Dmel: FBgn0003720, tll, tailless, [RH, Score=205, Expect=3e-59]} {Celegans: WBGene00003657, nhr-67, Nuclear hormone receptor family member nhr-67, [RH, Score=194, Expect=1e-55]} {Smed: dd_Smed_v6_21347_0_1, dd_Smed_v6_21347_0_1, [RH, Score=189, Expect=4e-54]} {RNA1509_39776} {RNA1310_21550} {RNA815_27099.1}
15. MligTC455_40989 801 16.68 Mlig455_016294

Neo: -

Age: logFC(26M/2M)=0.270

PKD2 1.78 - - - 0.826 0.954 - Mlig455_016294 {REF} {Length: 3179} {Pfam: Polycystin cation channel [PF08016.14, score=486.5]; Ion transport protein [PF00520.33, score=90.3]; EF hand [PF00036.34, score=23.7]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=718, Expect=0.0]; ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [RH, Score=712, Expect=0.0]} {Mouse: ENSMUSG00000037578, Pkd2l1, polycystic kidney disease 2-like 1, [RH, Score=704, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [RH, Score=310, Expect=2e-91]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [RH, Score=370, Expect=7e-116]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_14023, RNA1509_24240} {RNA1310_4836.1, RNA1509_14023, RNA1509_24240} {RNA1509_14023, RNA1509_24240, RNA815_4677}
16. MligTC455_48766 985 20.53 Mlig455_020052, Mlig455_022298

Neo: -

Age: logFC(26M/2M)=-0.287

ODF3 1.777 - - - 0.956 0.821 -

Mlig455_020052 {REF} {Length: 1742} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=82.0]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=188, Expect=6e-59]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=187, Expect=1e-58]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=2e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [Score=304, Expect=4e-105]} {RNA1509_28289, RNA1509_56680} {RNA1310_15149, RNA1509_56680} {RNA1509_56680, RNA815_9422}

Mlig455_022298 {REF} {Length: 2031} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=82.0]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=188, Expect=6e-59]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=187, Expect=1e-58]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=2e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [Score=304, Expect=4e-105]} {RNA1509_28289, RNA1509_54276} {RNA1310_15149, RNA1509_28289, RNA1509_54276} {RNA1509_28289, RNA1509_54276, RNA815_9422}
17. MligTC455_27520 1983 41.32 Mlig455_050045, Mlig455_054023

Neo: -

Age: logFC(26M/2M)=-0.596

ABCG2 1.761 - - - 0.964 0.797 -

Mlig455_050045 {REF} {Length: 2545} {Pfam: ABC-2 type transporter [PF01061.26, score=101.6]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=89.7, Expect=9e-19]} {Mouse: ENSMUSG00000032131, Abcg4, ATP binding cassette subfamily G member 4, [Score=87.4, Expect=4e-18]} {Dmel: FBgn0020445, E23, Early gene at 23, [Score=157, Expect=9e-42]} {Celegans: WBGene00015479, wht-1, ABC transporter ATP-binding protein/permease wht-1, [Score=78.2, Expect=2e-15]} {Smed: dd_Smed_v6_4142_0_1, dd_Smed_v6_4142_0_1, [Score=76.3, Expect=2e-15]} {RNA1509_2777} {RNA1310_8975.1} {RNA815_1994.2}

Mlig455_054023 {REF} {Length: 3295} {Pfam: ABC transporter [PF00005.29, score=96.5]; ABC-2 type transporter [PF01061.26, score=79.8]; ABC-2 type transporter [PF19055.2, score=50.3]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=25.7]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=212, Expect=1e-60]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=212, Expect=5e-61]; ENSMUSG00000024254, Abcg8, ATP binding cassette subfamily G member 8, [Score=202, Expect=7e-57]} {Dmel: FBgn0020445, E23, Early gene at 23, [Score=333, Expect=4e-103]} {Celegans: WBGene00015479, wht-1, ABC transporter ATP-binding protein/permease wht-1, [Score=204, Expect=3e-58]} {Smed: dd_Smed_v6_8560_0_1, dd_Smed_v6_8560_0_1, [Score=196, Expect=7e-55]} {RNA1509_2777} {RNA1310_8975.1, RNA1509_2777} {RNA1509_2777, RNA815_1994.2}
18. MligTC455_45495 988 20.58 Mlig455_010003

Neo: -

Age: logFC(26M/2M)=0.384

Region-enriched R2: 2.517/0.00003

CAV2 1.756 - - - 0.952 0.804 - Mlig455_010003 {REF} {Length: 748} {Pfam: Caveolin [PF01146.19, score=125.0]} {Human: ENSG00000105971, CAV2, caveolin 2, [Score=85.5, Expect=3e-21]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [Score=89.4, Expect=7e-23]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=79.0, Expect=2e-18]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=153, Expect=1e-48]} {RNA1509_20287} {RNA1310_50581.1} {RNA815_31873}
19. MligTC455_51575 571 11.89 Mlig455_022958

Neo: -

Age: Up-Down-Down

CCDC57 1.715 - - 0.764 - 0.951 - Mlig455_022958 {REF} {Length: 3808} {Human: ENSG00000176155, CCDC57, coiled-coil domain containing 57, [RH, Score=111, Expect=2e-24]} {Smed: dd_Smed_v6_10967_0_1, dd_Smed_v6_10967_0_1, [RH, Score=201, Expect=1e-53]} {RNA1509_12720, RNA1509_57308, RNA1509_57386, RNA1509_9404} {RNA1310_3169, RNA1509_12720, RNA1509_57308, RNA1509_57386, RNA1509_9404} {RNA1509_12720, RNA1509_57308, RNA1509_57386, RNA1509_9404, RNA815_2625}
20. MligTC455_32429 686 14.29 Mlig455_039345

Neo: -

Age: Down-Up-Down

NWD2 1.712 - - - 0.755 0.957 - Mlig455_039345 {REF} {Length: 7113} {TRANSSPLICED} {Pfam: NACHT domain [PF05729.14, score=42.9]; Domain of unknown function (DUF4062) [PF13271.8, score=39.4]; AAA ATPase domain [PF13191.8, score=39.2]; AAA domain [PF13401.8, score=21.0]; ATPase domain predominantly from Archaea [PF01637.20, score=18.6]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=459, Expect=1e-134]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [RH, Score=452, Expect=2e-132]} {Dmel: FBgn0038397, CG10185, [Score=558, Expect=3e-170]} {Celegans: WBGene00020254, T05C3.2, [Score=565, Expect=2e-172]} {Smed: dd_Smed_v6_11085_0_2, dd_Smed_v6_11085_0_2, [Score=322, Expect=3e-89]} {RNA1509_3054, RNA1509_44221} {RNA1310_322, RNA1509_44221} {RNA1509_44221, RNA815_139.1}
21. MligTC455_53037 13249 276.01 Mlig455_032646

Neo: -

Age: -

1.704 - - - 0.956 0.748 - Mlig455_032646 {REF} {Length: 968} {RNA1509_30269, RNA1509_4133, RNA1509_8761} {RNA1310_40499.1, RNA1509_30269, RNA1509_4133, RNA1509_8761} {RNA1509_30269, RNA1509_4133, RNA1509_8761, RNA815_19419.1}
22. MligTC455_45702 777 16.19 Mlig455_008333

Neo: -

Age: logFC(26M/2M)=-0.568

ADAM12 1.698 - - - 0.968 0.730 - Mlig455_008333 {REF} {Length: 3197} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=123.0]; Disintegrin [PF00200.25, score=72.7]; Metallo-peptidase family M12 [PF13688.8, score=51.8]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=42.1]; ADAM cysteine-rich [PF08516.14, score=40.6]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=38.9]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=38.3]} {Human: ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=236, Expect=1e-64]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=231, Expect=3e-64]; ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=229, Expect=4e-63]} {Mouse: ENSMUSG00000054555, Adam12, a disintegrin and metallopeptidase domain 12 (meltrin alpha), [Score=228, Expect=2e-62]; ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=226, Expect=5e-62]; ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [Score=225, Expect=1e-61]} {Dmel: FBgn0265140, Meltrin, [Score=250, Expect=7e-70]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=216, Expect=2e-58]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=231, Expect=6e-63]} {RNA1509_7145} {RNA1310_4464.1, RNA1509_7145} {RNA1509_7145, RNA815_1440.1}
23. MligTC455_29297 533 11.1 Mlig455_033889

Neo: -

Age: Up-Down-Up

Region-enriched R2: 2.005/0.00703

1.69 - - - 0.960 0.730 - Mlig455_033889 {REF} {Length: 4369} {TRANSSPLICED} {Pfam: Phage integrase family [PF00589.24, score=26.0]} {RNA1509_19505, RNA1509_60118} {RNA1310_1707, RNA1509_19505, RNA1509_60118} {RNA1509_19505, RNA1509_60118, RNA815_3378}
24. MligTC455_45977 2671 55.65 Mlig455_023593, Mlig455_068112

Neo: -

Age: logFC(26M/2M)=-0.892

Region-enriched R2: 2.870/0.00031

MUC4 1.665 - - - 0.715 0.950 -

Mlig455_023593 {REF} {Length: 6716} {TRANSSPLICED} {Pfam: Calcium-binding EGF domain [PF07645.17, score=81.4]; EGF-like domain [PF00008.29, score=74.6]; EGF domain [PF12947.9, score=64.6]; Complement Clr-like EGF-like [PF12662.9, score=58.7]; von Willebrand factor type D domain [PF00094.27, score=54.6]; Coagulation Factor Xa inhibitory site [PF14670.8, score=40.9]; Human growth factor-like EGF [PF12661.9, score=38.7]; Nidogen-like [PF06119.16, score=25.5]} {Human: ENSG00000278303, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000145113, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000277585, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000273822, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000273984, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000276613, MUC4, mucin 4, cell surface associated, [RH, Score=137, Expect=2e-31]; ENSG00000278468, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=6e-31]} {Mouse: ENSMUSG00000079620, Muc4, mucin 4, [RH, Score=112, Expect=6e-24]} {Dmel: FBgn0004647, N, Notch, [Score=103, Expect=2e-21]} {Celegans: WBGene00000792, crb-1, Drosophila CRumBs homolog, [Score=94.0, Expect=1e-18]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=92.0, Expect=3e-18]} {RNA1509_5446} {RNA1310_1366} {RNA815_327.2}

Mlig455_068112 {REF} {Length: 6638} {TRANSSPLICED} {Pfam: Calcium-binding EGF domain [PF07645.17, score=82.1]; EGF-like domain [PF00008.29, score=75.3]; EGF domain [PF12947.9, score=65.2]; Complement Clr-like EGF-like [PF12662.9, score=59.4]; von Willebrand factor type D domain [PF00094.27, score=54.7]; Coagulation Factor Xa inhibitory site [PF14670.8, score=41.6]; Human growth factor-like EGF [PF12661.9, score=39.4]; Nidogen-like [PF06119.16, score=25.6]} {Human: ENSG00000273822, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000277585, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000276613, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000273984, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000278303, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=1e-30]; ENSG00000145113, MUC4, mucin 4, cell surface associated, [RH, Score=135, Expect=7e-31]; ENSG00000278468, MUC4, mucin 4, cell surface associated, [RH, Score=133, Expect=3e-30]} {Mouse: ENSMUSG00000079620, Muc4, mucin 4, [RH, Score=110, Expect=2e-23]} {Dmel: FBgn0004647, N, Notch, [Score=103, Expect=2e-21]} {Celegans: WBGene00000792, crb-1, Drosophila CRumBs homolog, [Score=93.6, Expect=1e-18]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=92.4, Expect=3e-18]} {RNA1509_20713, RNA1509_53794, RNA1509_5446} {RNA1310_1366, RNA1509_20713, RNA1509_53794} {RNA1509_20713, RNA1509_53794, RNA815_327.2}
25. MligTC455_53843 1448 30.17 Mlig455_048664

Neo: -

Age: logFC(26M/2M)=0.488

1.664 - - - 0.954 0.710 - Mlig455_048664 {REF} {Length: 1660} {RNA1509_15580} {RNA1310_24090, RNA1509_15580} {RNA1509_15580, RNA815_10676.2}
26. MligTC455_14447 1552 32.32 Mlig455_044090

Neo: -

Age: Down-Up-Down

1.663 - - - 0.960 - 0.703 Mlig455_044090 {REF} {Length: 628} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4513) [PF14983.8, score=47.2]} {Smed: dd_Smed_v6_9820_0_1, dd_Smed_v6_9820_0_1, [RH, Score=92.8, Expect=2e-25]} {RNA1509_15130, RNA1509_30396} {RNA1310_35608, RNA1509_15130} {RNA1509_15130, RNA815_26600}
27. MligTC455_46654 2137 44.52 Mlig455_051380

Neo: -

Age: Down-Up-Down

EPS8L2 1.655 - - - 0.705 0.950 - Mlig455_051380 {REF} {Length: 3696} {TRANSSPLICED} {Pfam: Phosphotyrosine-binding domain [PF08416.15, score=42.1]; SH3 domain [PF00018.30, score=23.9]} {Human: ENSG00000177106, EPS8L2, EPS8 like 2, [RH, Score=158, Expect=5e-40]; ENSG00000151491, EPS8, epidermal growth factor receptor pathway substrate 8, [RH, Score=153, Expect=5e-38]} {Mouse: ENSMUSG00000015766, Eps8, epidermal growth factor receptor pathway substrate 8, [RH, Score=159, Expect=6e-40]; ENSMUSG00000025504, Eps8l2, EPS8-like 2, [RH, Score=154, Expect=8e-39]} {Dmel: FBgn0029095, aru, arouser, [RH, Score=161, Expect=4e-41]} {Celegans: WBGene00001330, eps-8, EPS (Human endocytosis) related; Epidermal growth factor receptor pathway substrate 8 splice variant A, [RH, Score=215, Expect=7e-60]} {Smed: dd_Smed_v6_4256_0_1, dd_Smed_v6_4256_0_1, [RH, Score=79.0, Expect=4e-15]} {RNA1509_4398} {RNA1310_3514} {RNA815_6294}
28. MligTC455_53844 1403 29.24 Mlig455_051626

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.540

0.969 - - - 0.969 - - Mlig455_051626 {REF} {Length: 1671} {RNA1509_15580} {RNA1310_24090} {RNA815_10676.2}
29. MligTC455_19359 1441 30.02 Mlig455_010318

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.258

0.966 - - - 0.966 - - Mlig455_010318 {REF} {Length: 851} {RNA1509_15410, RNA1509_52437} {RNA1310_43315.2, RNA1509_15410, RNA1509_52437} {RNA1509_15410, RNA1509_52437, RNA815_22018.1}
30. MligTC455_26438 766 15.96 Mlig455_013540

Neo: -

Age: Up-Up-Down

Region-enriched R5: 1.411/0.00004

0.964 - - - 0.964 - - Mlig455_013540 {REF} {Length: 7185} {Pfam: Zinc knuckle [PF00098.25, score=24.1]} {RNA1509_10005} {RNA1310_13005} {RNA815_1257.1}
31. MligTC455_42114 188 3.92 Mlig455_034293

Neo: -

Age: Down-Up-Up

0.963 - - - - 0.963 - Mlig455_034293 {REF} {Length: 1926} {Pfam: Glycosyltransferase family 92 [PF01697.29, score=89.5]} {Dmel: FBgn0032506, CG9395, [Score=87.4, Expect=7e-18]} {Celegans: WBGene00008763, F13G3.3, Glycosyltransferase family 92 protein F13G3.3, [RH, Score=49.7, Expect=4e-06]} {Smed: dd_Smed_v6_5401_0_1, dd_Smed_v6_5401_0_1, [Score=198, Expect=4e-58]} {RNA1310_14481.1} {RNA815_5740.1}
32. MligTC455_41324 401 8.35 Mlig455_024997

Neo: -

Age: Up-Down-Down

CCDC151 0.961 - - - 0.961 - - Mlig455_024997 {REF} {Length: 2376} {TRANSSPLICED} {Human: ENSG00000198003, CCDC151, coiled-coil domain containing 151, [Score=251, Expect=5e-75]} {Mouse: ENSMUSG00000039632, Ccdc151, coiled-coil domain containing 151, [Score=261, Expect=4e-79]} {Dmel: FBgn0036219, CCDC151, Coiled-coil domain containing protein 151, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_4526_0_1, dd_Smed_v6_4526_0_1, [Score=463, Expect=3e-158]} {RNA1509_18758} {RNA1310_9513.1, RNA1509_18758} {RNA1509_18758, RNA815_13766}
33. MligTC455_21926 225 4.69 Mlig455_003629

Neo: -

Age: -

0.956 - - - - 0.956 - Mlig455_003629 {REF} {Length: 2548} {RNA1509_15605} {RNA1310_4409.1} {RNA815_14135}
34. MligTC455_29296 451 9.39 Mlig455_033882

Neo: -

Age: -

Region-enriched R2: 2.069/0.00679

0.955 - - - 0.955 - - Mlig455_033882 {REF} {Length: 400} {NoTransDecoderORF} {RNA1509_17728} {RNA1310_48181} {RNA815_50465}
35. MligTC455_41588 489 10.19 Mlig455_012995

Neo: -

Age: -

ZDHHC2 0.954 - - 0.954 - - - Mlig455_012995 {REF} {Length: 1362} {TRANSSPLICED} {Pfam: DHHC palmitoyltransferase [PF01529.22, score=116.2]} {Human: ENSG00000104219, ZDHHC2, zinc finger DHHC-type containing 2, [RH, Score=286, Expect=6e-95]} {Mouse: ENSMUSG00000021969, Zdhhc20, zinc finger, DHHC domain containing 20, [RH, Score=286, Expect=1e-94]; ENSMUSG00000039470, Zdhhc2, zinc finger, DHHC domain containing 2, [RH, Score=283, Expect=1e-93]} {Dmel: FBgn0033474, CG1407, [RH, Score=296, Expect=6e-99]} {Celegans: WBGene00014075, dhhc-4, Zinc finger DHHC domain-containing protein 4, [RH, Score=213, Expect=1e-66]} {Smed: dd_Smed_v6_7776_0_2, dd_Smed_v6_7776_0_2, [RH, Score=245, Expect=6e-80]} {RNA1509_23962, RNA1509_59427} {RNA1310_14192, RNA1509_59427} {RNA1509_59427, RNA815_5095.2}
36. MligTC455_41589 473 9.85 Mlig455_013031

Neo: -

Age: -

Region-enriched R5: 1.584/0.04106

0.954 - - 0.954 - - - Mlig455_013031 {REF} {Length: 627} {NoTransDecoderORF} {RNA1509_23962} {RNA1310_14192} {RNA815_5095.2}
37. MligTC455_42115 167 3.49 Mlig455_034257

Neo: -

Age: -

0.952 - - - - 0.952 - Mlig455_034257 {REF} {Length: 1854} {Pfam: Glycosyltransferase family 92 [PF01697.29, score=88.5]} {Dmel: FBgn0032506, CG9395, [Score=84.0, Expect=8e-17]} {Smed: dd_Smed_v6_5401_0_1, dd_Smed_v6_5401_0_1, [Score=204, Expect=1e-60]} {RNA1310_14481.1} {RNA815_5740.1}
38. MligTC455_52973 404 8.43 Mlig455_006681

Neo: -

Age: logFC(26M/2M)=-0.512

Region-enriched R4: 1.946/0.02869

0.952 - - - 0.952 - - Mlig455_006681 {REF} {Length: 2350} {TRANSSPLICED} {Pfam: Gamma-glutamyl cyclotransferase, AIG2-like [PF06094.14, score=41.4]; AIG2-like family [PF13772.8, score=36.0]} {RNA1509_12874} {RNA1310_10210.1} {RNA815_7283}
39. MligTC455_22763 1893 39.44 Mlig455_026105

Neo: -

Age: logFC(26M/2M)=-0.375

Region-enriched R2: 1.072/0.04204

ELOVL4 0.951 - - - 0.951 - - Mlig455_026105 {REF} {Length: 3163} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=218.7]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [RH, Score=322, Expect=4e-110]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [RH, Score=318, Expect=2e-108]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [RH, Score=218, Expect=6e-70]} {Celegans: WBGene00001245, elo-7, Elongation of very long chain fatty acids protein, [Score=80.5, Expect=3e-17]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [RH, Score=358, Expect=3e-125]} {RNA1509_16116, RNA1509_31650, RNA1509_5216} {RNA1310_6579.2, RNA1509_16116, RNA1509_31650, RNA1509_5216} {RNA1509_16116, RNA1509_31650, RNA1509_5216, RNA815_7910}
40. MligTC455_20828 43 0.91 Mlig455_039990

Neo: -

Age: -

0.95 - - - - 0.950 - Mlig455_039990 {REF} {Length: 3053} {NoTransDecoderORF} {RNA1310_18595} {RNA815_11725}
41. MligTC455_24509 558 11.64 Mlig455_008130, Mlig455_008131

Neo: -

Age: Down-Up-Down

Region-enriched R2: 2.163/0.00814
Region-enriched R7: 2.094/0.00103

0.95 - - - 0.950 - -

Mlig455_008130 {REF} {Length: 1564} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_32433} {RNA1310_19716} {RNA815_13109}

Mlig455_008131 {REF} {Length: 1564} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_32433} {RNA1310_19716} {RNA815_13109}
42. MligTC455_42089 2017 42.02 Mlig455_039671

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.579

Region-enriched R4: 1.250/0.00077
Region-enriched R3: 1.030/0.00188

CALM2 0.95 - - - - 0.950 - Mlig455_039671 {REF} {Length: 1183} {Pfam: EF hand [PF00036.34, score=95.7]; EF-hand domain [PF13405.8, score=88.1]; EF-hand domain pair [PF13499.8, score=88.0]; EF hand [PF13202.8, score=67.8]; EF-hand domain pair [PF13833.8, score=67.7]; Caleosin related protein [PF05042.15, score=30.7]; EF-hand domain [PF14658.8, score=29.4]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=22.6]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=19.7]; Dockerin type I domain [PF00404.20, score=19.6]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=146, Expect=6e-45]; ENSG00000160014, CALM3, calmodulin 3, [Score=146, Expect=6e-45]; ENSG00000198668, CALM1, calmodulin 1, [Score=146, Expect=5e-45]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=146, Expect=4e-45]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=146, Expect=4e-45]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=146, Expect=4e-45]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=139, Expect=2e-42]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=145, Expect=7e-45]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=145, Expect=7e-45]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=145, Expect=5e-45]} {RNA1509_16438, RNA1509_36384, RNA1509_8935} {RNA1310_33320, RNA1509_16438, RNA1509_36384, RNA1509_8935} {RNA1509_16438, RNA1509_36384, RNA1509_8935, RNA815_16618}

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