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Results for MligTC455_45702

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_45702 777 16.19 Mlig455_008333

Neo: -

Age: logFC(26M/2M)=-0.568

 ADAM12 Mlig455_008333 {REF} {Length: 3197} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=123.0]; Disintegrin [PF00200.25, score=72.7]; Metallo-peptidase family M12 [PF13688.8, score=51.8]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=42.1]; ADAM cysteine-rich [PF08516.14, score=40.6]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=38.9]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=38.3]} {Human: ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=236, Expect=1e-64]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=231, Expect=3e-64]; ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=229, Expect=4e-63]} {Mouse: ENSMUSG00000054555, Adam12, a disintegrin and metallopeptidase domain 12 (meltrin alpha), [Score=228, Expect=2e-62]; ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=226, Expect=5e-62]; ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [Score=225, Expect=1e-61]} {Dmel: FBgn0265140, Meltrin, [Score=250, Expect=7e-70]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=216, Expect=2e-58]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=231, Expect=6e-63]} {RNA1509_7145} {RNA1310_4464.1, RNA1509_7145} {RNA1509_7145, RNA815_1440.1}

Cumulative graph for MligTC455_45702

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.41 4.146 0.07369 0.60128
RegionR2 -0.132 4.146 0.73532 1.00000
RegionR3 -0.631 4.146 0.06080 0.43441
RegionR4 -0.187 4.146 0.65032 0.95318
RegionR5 -1.311 4.146 0.00011 0.00174
RegionR6 -0.508 4.146 0.13524 0.66065
RegionR7 0.326 4.146 0.41627 1.00000
RegionR8 1.034 4.146 0.02206 0.28975

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -3.041 4.146 0.02583 0.60362
RegenerationR2 0.022 4.146 0.95059 1.00000
RegenerationR3 -0.154 4.146 0.70123 0.94789
RegenerationR4 -1.137 4.146 0.00795 0.13192
RegenerationR5 -0.813 4.146 0.06031 0.39110
RegenerationR6 -1.296 4.146 0.00398 0.07533
RegenerationBL -1.94 4.146 0.00032 0.01045
RegenerationTP -1.541 4.146 0.00194 0.07103


Genes with expression patterns similar to MligTC455_45702

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_45702 777 16.19 Mlig455_008333

Neo: -

Age: logFC(26M/2M)=-0.568

 ADAM12 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_008333 {REF} {Length: 3197} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=123.0]; Disintegrin [PF00200.25, score=72.7]; Metallo-peptidase family M12 [PF13688.8, score=51.8]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=42.1]; ADAM cysteine-rich [PF08516.14, score=40.6]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=38.9]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=38.3]} {Human: ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=236, Expect=1e-64]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=231, Expect=3e-64]; ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=229, Expect=4e-63]} {Mouse: ENSMUSG00000054555, Adam12, a disintegrin and metallopeptidase domain 12 (meltrin alpha), [Score=228, Expect=2e-62]; ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=226, Expect=5e-62]; ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [Score=225, Expect=1e-61]} {Dmel: FBgn0265140, Meltrin, [Score=250, Expect=7e-70]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=216, Expect=2e-58]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=231, Expect=6e-63]} {RNA1509_7145} {RNA1310_4464.1, RNA1509_7145} {RNA1509_7145, RNA815_1440.1}
2. MligTC455_21635 1157 24.11 Mlig455_026396

Neo: -

Age: -

 SLC6A5 3.422 0.763 - - 0.882 0.957 0.820 Mlig455_026396 {REF} {Length: 3636} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=612.2]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=486, Expect=2e-161]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=490, Expect=6e-163]} {Dmel: FBgn0034911, CG5549, [Score=499, Expect=2e-162]} {Celegans: WBGene00004905, snf-6, Sodium-dependent acetylcholine transporter, [RH, Score=374, Expect=2e-119]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=459, Expect=1e-152]} {RNA1509_26562} {RNA1310_4707.2, RNA1509_26562} {RNA1509_26562, RNA815_1349.2}
3. MligTC455_41324 401 8.35 Mlig455_024997

Neo: -

Age: Up-Down-Down

 CCDC151 3.355 - 0.733 - 0.968 0.869 0.785 Mlig455_024997 {REF} {Length: 2376} {TRANSSPLICED} {Human: ENSG00000198003, CCDC151, coiled-coil domain containing 151, [Score=251, Expect=5e-75]} {Mouse: ENSMUSG00000039632, Ccdc151, coiled-coil domain containing 151, [Score=261, Expect=4e-79]} {Dmel: FBgn0036219, CCDC151, Coiled-coil domain containing protein 151, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_4526_0_1, dd_Smed_v6_4526_0_1, [Score=463, Expect=3e-158]} {RNA1509_18758} {RNA1310_9513.1, RNA1509_18758} {RNA1509_18758, RNA815_13766}
4. MligTC455_14904 4225 88.01 Mlig455_037596

Neo: -

Age: logFC(26M/2M)=0.385

Region-enriched R8: 1.541/0.00053

 3.266 0.744 - - 0.955 0.759 0.808 Mlig455_037596 {REF} {Length: 2914} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=59.3, Expect=3e-09]} {RNA1509_17730, RNA1509_4337} {RNA1310_7259, RNA1509_17730} {RNA1509_17730, RNA815_206}
5. MligTC455_18648 470 9.79 Mlig455_063464

Neo: -

Age: logFC(26M/2M)=-0.661

 3.211 - 0.950 - 0.730 0.829 0.702 Mlig455_063464 {REF} {Length: 1671} {Pfam: BTB/POZ domain [PF00651.33, score=33.9]} {RNA1509_21795, RNA1509_45066} {RNA1310_23212, RNA1509_21795} {RNA1509_21795, RNA815_2283.1}
6. MligTC455_39781 4052 84.43 Mlig455_031206

Neo: -

Age: -

Region-specific R2: 2.205

Region-enriched R2: 1.861/0.00000

 CLVS2 2.655 - - - 0.767 0.963 0.925 Mlig455_031206 {REF} {Length: 2771} {Pfam: CRAL/TRIO domain [PF00650.22, score=62.0]} {Human: ENSG00000146352, CLVS2, clavesin 2, [Score=112, Expect=5e-28]; ENSG00000177182, CLVS1, clavesin 1, [Score=112, Expect=9e-28]; ENSG00000124120, TTPAL, alpha tocopherol transfer protein like, [Score=110, Expect=3e-27]} {Mouse: ENSMUSG00000019785, Clvs2, clavesin 2, [Score=112, Expect=4e-28]; ENSMUSG00000041216, Clvs1, clavesin 1, [Score=111, Expect=1e-27]; ENSMUSG00000017679, Ttpal, tocopherol (alpha) transfer protein-like, [Score=110, Expect=3e-27]} {Dmel: FBgn0036289, CG10657, [RH, Score=120, Expect=3e-31]} {Smed: dd_Smed_v6_12402_0_3, dd_Smed_v6_12402_0_3, [RH, Score=241, Expect=7e-78]} {RNA1509_17672, RNA1509_26784, RNA1509_33745, RNA1509_3681, RNA1509_37291, RNA1509_38202} {RNA1310_7594.1, RNA1509_17672, RNA1509_26784, RNA1509_33745, RNA1509_3681, RNA1509_37291, RNA1509_38202} {RNA1509_17672, RNA1509_26784, RNA1509_33745, RNA1509_3681, RNA1509_37291, RNA1509_38202, RNA815_4242.1}
7. MligTC455_29451 819 17.07 Mlig455_026453

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.590

 LMNTD1 2.624 - - - 0.852 0.952 0.820 Mlig455_026453 {REF} {Length: 3415} {Pfam: Intermediate filament protein [PF00038.23, score=53.0]; Lamin Tail Domain [PF00932.21, score=40.2]; Mechanosensitive ion channel porin domain [PF12795.9, score=18.4]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=148, Expect=6e-38]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=2e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=405, Expect=7e-127]} {RNA1509_7063} {RNA1310_3989.1} {RNA815_1147.1}
8. MligTC455_29450 827 17.23 Mlig455_026424

Neo: -

Age: logFC(26M/2M)=-0.523

 LMNTD1 2.617 - - - 0.843 0.954 0.820 Mlig455_026424 {REF} {Length: 3702} {Pfam: Intermediate filament protein [PF00038.23, score=52.8]; Lamin Tail Domain [PF00932.21, score=40.5]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=147, Expect=1e-37]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=142, Expect=7e-36]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.8, Expect=9e-13]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.4, Expect=9e-10]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=228, Expect=1e-62]} {RNA1509_16713, RNA1509_7063} {RNA1310_3989.1, RNA1509_16713, RNA1509_7063} {RNA1509_16713, RNA1509_7063, RNA815_1147.1}
9. MligTC455_23082 1608 33.5 Mlig455_024173

Neo: -

Age: -

 FAT4 2.603 - - - 0.959 0.795 0.849 Mlig455_024173 {REF} {Length: 8284} {Pfam: Cadherin domain [PF00028.19, score=731.9]; Cadherin-like [PF16184.7, score=111.8]; Cadherin-like [PF08266.14, score=26.5]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=544, Expect=2e-155]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=514, Expect=2e-146]} {Dmel: FBgn0284247, ds, dachsous, [Score=463, Expect=8e-131]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=276, Expect=4e-74]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=279, Expect=7e-75]} {RNA1509_848} {RNA1310_296} {RNA815_105}
10. MligTC455_21636 1201 25.01 Mlig455_026397

Neo: -

Age: logFC(26M/2M)=-0.592

 SLC6A5 2.574 - - - 0.884 0.956 0.734 Mlig455_026397 {REF} {Length: 3625} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=571.5]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=463, Expect=4e-154]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=466, Expect=2e-155]} {Dmel: FBgn0034911, CG5549, [Score=456, Expect=1e-147]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=350, Expect=8e-113]} {Smed: dd_Smed_v6_10458_0_2, dd_Smed_v6_10458_0_2, [Score=422, Expect=9e-141]} {RNA1509_11553, RNA1509_16390} {RNA1310_4707.1, RNA1509_11553, RNA1509_16390} {RNA1509_11553, RNA1509_16390, RNA815_1349.1}
11. MligTC455_49394 1184 24.68 Mlig455_041577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.255/0.02823

 2.556 - - 0.775 0.963 0.818 - Mlig455_041577 {REF} {Length: 928} {Pfam: Normal lung function maintenance, Low in Lung Cancer 1 protein [PF14945.8, score=24.7]} {Smed: dd_Smed_v6_6024_0_1, dd_Smed_v6_6024_0_1, [Score=97.8, Expect=1e-26]} {RNA1509_17780, RNA1509_38038} {RNA1310_47454, RNA1509_17780, RNA1509_38038} {RNA1509_17780, RNA1509_38038, RNA815_24792.1}
12. MligTC455_19359 1441 30.02 Mlig455_010318

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.258

 2.551 0.733 - - 0.965 - 0.853 Mlig455_010318 {REF} {Length: 851} {RNA1509_15410, RNA1509_52437} {RNA1310_43315.2, RNA1509_15410, RNA1509_52437} {RNA1509_15410, RNA1509_52437, RNA815_22018.1}
13. MligTC455_51072 1435 29.89 Mlig455_026765, Mlig455_051781

Neo: -

Age: logFC(26M/2M)=-0.451

 2.541 - - - 0.791 0.950 0.800

Mlig455_026765 {REF} {Length: 1860} {Pfam: Cytochrome b-c1 complex subunit 8 [PF10890.10, score=22.8]} {RNA1509_46733} {RNA1310_23599.1} {RNA815_9299.1}

Mlig455_051781 {REF} {Length: 1509} {RNA1509_22054, RNA1509_46733, RNA1509_53980} {RNA1310_23599.1, RNA1509_22054, RNA1509_46733, RNA1509_53980} {RNA1509_22054, RNA1509_46733, RNA1509_53980, RNA815_9299.1}
14. MligTC455_42465 378 7.88 Mlig455_050238

Neo: -

Age: -

 CCDC74B 2.541 - 0.962 - 0.717 - 0.862 Mlig455_050238 {REF} {Length: 2734} {TRANSSPLICED} {Pfam: Coiled-coil domain of unknown function [PF14916.8, score=52.5]; Coiled coil protein 74, C terminal [PF14917.8, score=44.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.9]} {Human: ENSG00000152076, CCDC74B, coiled-coil domain containing 74B, [RH, Score=57.4, Expect=1e-08]; ENSG00000163040, CCDC74A, coiled-coil domain containing 74A, [RH, Score=57.0, Expect=1e-08]} {Mouse: ENSMUSG00000041617, Ccdc74a, coiled-coil domain containing 74A, [RH, Score=54.3, Expect=5e-09]} {RNA1509_28309} {RNA1310_23099.2, RNA1509_28309} {RNA1509_28309, RNA815_11185}
15. MligTC455_31117 933 19.44 Mlig455_017721, Mlig455_057064, Mlig455_057078

Neo: -

Age: logFC(26M/2M)=-0.670

Region-enriched R2: 1.818/0.04375

 ADAM33, ADAM9 2.504 - 0.785 - 0.960 0.759 -

Mlig455_017721 {REF} {Length: 3292} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=127.8]; Metallo-peptidase family M12 [PF13688.8, score=71.8]; Disintegrin [PF00200.25, score=68.3]; ADAM cysteine-rich [PF08516.14, score=60.1]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=40.8]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=37.1]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=30.2]; Matrixin [PF00413.26, score=19.9]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [RH, Score=244, Expect=5e-69]} {Mouse: ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [RH, Score=254, Expect=3e-73]; ENSMUSG00000050190, Gm5346, predicted gene 5346, [RH, Score=251, Expect=7e-72]} {Dmel: FBgn0265140, Meltrin, [Score=272, Expect=3e-78]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [RH, Score=251, Expect=5e-71]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=225, Expect=1e-61]} {RNA1509_21514, RNA1509_7654} {RNA1310_9319.1, RNA1509_21514, RNA1509_7654} {RNA1509_21514, RNA1509_7654, RNA815_4173.1}

Mlig455_057064 {REF} {Length: 3604} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=128.4]; Metallo-peptidase family M12 [PF13688.8, score=69.3]; Disintegrin [PF00200.25, score=68.6]; ADAM cysteine-rich [PF08516.14, score=60.7]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=42.0]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=37.2]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=31.5]; Matrixin [PF00413.26, score=19.9]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [RH, Score=247, Expect=9e-71]} {Mouse: ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=256, Expect=1e-74]} {Dmel: FBgn0265140, Meltrin, [Score=270, Expect=2e-78]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=248, Expect=7e-71]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=226, Expect=7e-63]} {RNA1509_44914} {RNA1310_9319.1, RNA1509_44914} {RNA1509_44914, RNA815_4173.1}

Mlig455_057078 {REF} {Length: 1339} {Pfam: ADAM cysteine-rich [PF08516.14, score=75.6]; Disintegrin [PF00200.25, score=53.3]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=145, Expect=6e-38]; ENSG00000168594, ADAM29, ADAM metallopeptidase domain 29, [Score=145, Expect=1e-37]; ENSG00000139985, ADAM21, ADAM metallopeptidase domain 21, [Score=143, Expect=5e-37]; ENSG00000143537, ADAM15, ADAM metallopeptidase domain 15, [Score=142, Expect=8e-37]} {Mouse: ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=137, Expect=5e-35]; ENSMUSG00000028041, Adam15, a disintegrin and metallopeptidase domain 15 (metargidin), [Score=137, Expect=3e-35]; ENSMUSG00000011256, Adam19, a disintegrin and metallopeptidase domain 19 (meltrin beta), [Score=137, Expect=3e-35]; ENSMUSG00000046258, Adam29, a disintegrin and metallopeptidase domain 29, [Score=137, Expect=3e-35]; ENSMUSG00000008438, Adam21, a disintegrin and metallopeptidase domain 21, [Score=135, Expect=2e-34]; ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [Score=134, Expect=5e-34]; ENSMUSG00000062438, Adam1b, a disintegrin and metallopeptidase domain 1b, [Score=134, Expect=3e-34]; ENSMUSG00000031553, Adam3, a disintegrin and metallopeptidase domain 3 (cyritestin), [Score=133, Expect=1e-33]; ENSMUSG00000063900, Adam26b, a disintegrin and metallopeptidase domain 26B, [Score=131, Expect=3e-33]} {Dmel: FBgn0265140, Meltrin, [Score=153, Expect=1e-40]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=133, Expect=6e-34]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=132, Expect=1e-33]} {RNA1509_44914} {RNA1310_9319.1} {RNA815_4173.1}
16. MligTC455_40424 474 9.88 Mlig455_029322

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.888

 CALM2 2.48 - 0.746 0.963 - - 0.771 Mlig455_029322 {REF} {Length: 1020} {Pfam: EF-hand domain pair [PF13833.8, score=26.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=69.7, Expect=2e-14]; ENSG00000160014, CALM3, calmodulin 3, [Score=68.9, Expect=2e-14]; ENSG00000198668, CALM1, calmodulin 1, [Score=68.9, Expect=2e-14]; ENSG00000178363, CALML3, calmodulin like 3, [Score=68.2, Expect=3e-14]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=70.5, Expect=1e-14]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=68.9, Expect=1e-14]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=68.9, Expect=1e-14]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=67.4, Expect=3e-14]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=67.8, Expect=2e-14]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=67.8, Expect=2e-14]} {RNA1509_16604} {RNA1310_33121} {RNA815_17390}
17. MligTC455_52973 404 8.43 Mlig455_006681

Neo: -

Age: logFC(26M/2M)=-0.512

Region-enriched R4: 1.946/0.02869

 2.477 - - - 0.983 0.790 0.704 Mlig455_006681 {REF} {Length: 2350} {TRANSSPLICED} {Pfam: Gamma-glutamyl cyclotransferase, AIG2-like [PF06094.14, score=41.4]; AIG2-like family [PF13772.8, score=36.0]} {RNA1509_12874} {RNA1310_10210.1} {RNA815_7283}
18. MligTC455_20201 1626 33.88 Mlig455_025333

Neo: -

Age: logFC(26M/2M)=-0.331

 TRPA1 2.47 - 0.722 - 0.794 0.954 - Mlig455_025333 {REF} {Length: 5343} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=283.4]; Ankyrin repeat [PF00023.32, score=234.0]; Ankyrin repeats (many copies) [PF13637.8, score=227.4]; Ankyrin repeat [PF13606.8, score=217.2]; Ankyrin repeats (many copies) [PF13857.8, score=212.6]; Ion transport protein [PF00520.33, score=53.3]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=368, Expect=5e-107]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=363, Expect=2e-105]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=325, Expect=8e-92]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=2e-150]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [RH, Score=754, Expect=0.0]} {RNA1509_20092} {RNA1310_1173, RNA1509_20092} {RNA1509_20092, RNA815_336}
19. MligTC455_22761 288 6.01 Mlig455_005521

Neo: -

Age: -

 ELOVL4 2.452 - - - 0.957 0.775 0.720 Mlig455_005521 {REF} {Length: 1592} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=138.3]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [Score=220, Expect=1e-70]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [Score=216, Expect=1e-69]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [Score=145, Expect=2e-42]} {Celegans: WBGene00001244, elo-6, Elongation of very long chain fatty acids protein 6, [Score=52.8, Expect=4e-08]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [Score=215, Expect=7e-70]} {RNA1509_11261} {RNA1310_42181} {RNA815_6649.1}
20. MligTC455_45495 988 20.58 Mlig455_010003

Neo: -

Age: logFC(26M/2M)=0.384

Region-enriched R2: 2.517/0.00003

 CAV2 2.442 - - - 0.967 0.720 0.755 Mlig455_010003 {REF} {Length: 748} {Pfam: Caveolin [PF01146.19, score=125.0]} {Human: ENSG00000105971, CAV2, caveolin 2, [Score=85.5, Expect=3e-21]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [Score=89.4, Expect=7e-23]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=79.0, Expect=2e-18]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=153, Expect=1e-48]} {RNA1509_20287} {RNA1310_50581.1} {RNA815_31873}
21. MligTC455_46892 510 10.61 Mlig455_024306, Mlig455_024361

Neo: -

Age: -

 RAB8B 2.426 - - - 0.742 0.958 0.726

Mlig455_024306 {REF} {Length: 1532} {Pfam: Ras family [PF00071.24, score=212.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=118.0]; ADP-ribosylation factor family [PF00025.23, score=77.6]; Elongation factor Tu GTP binding domain [PF00009.29, score=27.4]; 50S ribosome-binding GTPase [PF01926.25, score=23.8]; Gtr1/RagA G protein conserved region [PF04670.14, score=23.5]; RsgA GTPase [PF03193.18, score=22.3]; Signal recognition particle receptor beta subunit [PF09439.12, score=18.9]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=257, Expect=4e-87]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=254, Expect=1e-85]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=256, Expect=6e-87]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=254, Expect=4e-86]} {Dmel: FBgn0262518, Rab8, [Score=245, Expect=1e-82]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=248, Expect=8e-84]} {Smed: dd_Smed_v6_3485_0_1, dd_Smed_v6_3485_0_1, [Score=251, Expect=2e-85]} {RNA1509_53476} {RNA1310_24855} {RNA815_9980.1}

Mlig455_024361 {REF} {Length: 1538} {Pfam: Ras family [PF00071.24, score=212.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=118.0]; ADP-ribosylation factor family [PF00025.23, score=77.6]; Elongation factor Tu GTP binding domain [PF00009.29, score=27.4]; 50S ribosome-binding GTPase [PF01926.25, score=23.8]; Gtr1/RagA G protein conserved region [PF04670.14, score=23.5]; RsgA GTPase [PF03193.18, score=22.3]; Signal recognition particle receptor beta subunit [PF09439.12, score=18.9]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=257, Expect=4e-87]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=254, Expect=1e-85]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=256, Expect=6e-87]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=254, Expect=4e-86]} {Dmel: FBgn0262518, Rab8, [Score=245, Expect=1e-82]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=248, Expect=8e-84]} {Smed: dd_Smed_v6_3485_0_1, dd_Smed_v6_3485_0_1, [Score=251, Expect=2e-85]} {RNA1509_53476} {RNA1310_24855, RNA1509_53476} {RNA1509_53476, RNA815_9980.1}
22. MligTC455_45703 433 9.03 Mlig455_018343

Neo: -

Age: -

Region-enriched R2: 1.674/0.02931

 ADAM12 1.878 - - - 0.964 - 0.914 Mlig455_018343 {REF} {Length: 4207} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=123.1]; Disintegrin [PF00200.25, score=73.1]; Metallo-peptidase family M12 [PF13688.8, score=48.1]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=40.5]; ADAM cysteine-rich [PF08516.14, score=39.9]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=39.4]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=37.8]} {Human: ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=231, Expect=4e-64]; ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=230, Expect=2e-63]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=229, Expect=9e-64]; ENSG00000139985, ADAM21, ADAM metallopeptidase domain 21, [Score=224, Expect=1e-61]; ENSG00000069206, ADAM7, ADAM metallopeptidase domain 7, [Score=222, Expect=1e-60]; ENSG00000042980, ADAM28, ADAM metallopeptidase domain 28, [Score=222, Expect=1e-60]} {Mouse: ENSMUSG00000054555, Adam12, a disintegrin and metallopeptidase domain 12 (meltrin alpha), [Score=228, Expect=3e-62]; ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=226, Expect=4e-62]; ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [Score=224, Expect=3e-61]} {Dmel: FBgn0265140, Meltrin, [Score=247, Expect=1e-68]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=219, Expect=3e-59]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=222, Expect=6e-60]} {RNA1509_54780, RNA1509_7145} {RNA1310_4464.2, RNA1509_54780} {RNA1509_54780, RNA815_1440.1}
23. MligTC455_23787 935 19.48 Mlig455_003434, Mlig455_030657

Neo: -

Age: logFC(26M/2M)=-0.252

 LRRC74B 1.857 - 0.904 - 0.953 - -

Mlig455_003434 {REF} {Length: 2540} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=84.8]; EF-hand domain pair [PF13499.8, score=40.1]; EF hand [PF00036.34, score=35.8]; Leucine Rich repeats (2 copies) [PF12799.9, score=31.3]; EF-hand domain [PF13405.8, score=30.8]; EF-hand domain pair [PF13833.8, score=29.5]; Leucine Rich Repeat [PF00560.35, score=25.9]; EF hand [PF13202.8, score=19.7]} {Human: ENSG00000187905, LRRC74B, leucine rich repeat containing 74B, [RH, Score=249, Expect=2e-77]} {Mouse: ENSMUSG00000059114, Lrrc74a, leucine rich repeat containing 74A, [RH, Score=248, Expect=4e-76]} {Dmel: FBgn0051635, CG31635, [Score=50.8, Expect=2e-06]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=63.5, Expect=2e-10]} {Smed: dd_Smed_v6_15909_0_1, dd_Smed_v6_15909_0_1, [RH, Score=389, Expect=9e-131]} {RNA1509_28593} {RNA1310_6555} {RNA815_1932.1}

Mlig455_030657 {REF} {Length: 2784} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=84.8]; EF-hand domain pair [PF13499.8, score=40.1]; EF hand [PF00036.34, score=35.8]; Leucine Rich repeats (2 copies) [PF12799.9, score=31.3]; EF-hand domain [PF13405.8, score=30.8]; EF-hand domain pair [PF13833.8, score=29.5]; Leucine Rich Repeat [PF00560.35, score=25.9]; EF hand [PF13202.8, score=19.7]} {Human: ENSG00000187905, LRRC74B, leucine rich repeat containing 74B, [RH, Score=249, Expect=2e-77]} {Mouse: ENSMUSG00000059114, Lrrc74a, leucine rich repeat containing 74A, [RH, Score=248, Expect=4e-76]} {Dmel: FBgn0051635, CG31635, [Score=50.8, Expect=3e-06]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=63.5, Expect=2e-10]} {Smed: dd_Smed_v6_15909_0_1, dd_Smed_v6_15909_0_1, [RH, Score=389, Expect=7e-131]} {RNA1509_6554} {RNA1310_6555} {RNA815_1932.1}
24. MligTC455_33464 941 19.61 Mlig455_004195

Neo: -

Age: -

Region-enriched R8: 2.004/0.00108
Region-enriched R7: 1.733/0.00048
Region-enriched R2: 1.587/0.00611

Regeneration-downregulated BL: -2.932

Regeneration-depleted BL: -2.932

 1.83 - - - 0.877 0.953 - Mlig455_004195 {REF} {Length: 953} {RNA1509_58242} {RNA1310_25946.1} {RNA815_12422}
25. MligTC455_54147 2046 42.63 Mlig455_062289

Neo: -

Age: Down-Up-Down

 DRC7 1.808 - - - - 0.973 0.835 Mlig455_062289 {REF} {Length: 3093} {Human: ENSG00000159625, DRC7, dynein regulatory complex subunit 7, [Score=642, Expect=0.0]} {Mouse: ENSMUSG00000031786, Drc7, dynein regulatory complex subunit 7, [Score=629, Expect=0.0]} {Dmel: FBgn0083946, lobo, lost boys, [Score=226, Expect=1e-61]} {Smed: dd_Smed_v6_12588_0_1, dd_Smed_v6_12588_0_1, [Score=588, Expect=0.0]} {RNA1509_1230} {RNA1310_4483} {RNA815_1294}
26. MligTC455_19360 1380 28.75 Mlig455_065641

Neo: -

Age: logFC(26M/2M)=-0.869

 1.807 - - - 0.952 - 0.855 Mlig455_065641 {REF} {Length: 843} {RNA1509_52437} {RNA1310_43315.2} {RNA815_22018.1}
27. MligTC455_18481 1416 29.5 Mlig455_061762

Neo: -

Age: Down-Down-Up

Region-enriched R2: 1.816/0.04103

 IFT88 1.792 - - - 0.830 0.962 - Mlig455_061762 {REF} {Length: 3149} {Pfam: Tetratricopeptide repeat [PF07719.19, score=111.4]; Tetratricopeptide repeat [PF00515.30, score=99.7]; Tetratricopeptide repeat [PF13424.8, score=98.0]; Tetratricopeptide repeat [PF13181.8, score=76.4]; Tetratricopeptide repeat [PF14559.8, score=73.3]; Tetratricopeptide repeat [PF13174.8, score=71.7]; Tetratricopeptide repeat [PF13432.8, score=71.0]; Tetratricopeptide repeat [PF13428.8, score=70.9]; Tetratricopeptide repeat [PF13176.8, score=61.5]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=56.3]; TPR repeat [PF13414.8, score=50.2]; Tetratricopeptide repeat [PF13371.8, score=40.4]; Tetratricopeptide repeat [PF13374.8, score=31.9]; Tetratricopeptide repeat-like domain [PF09976.11, score=28.6]; Tetratricopeptide repeat [PF13431.8, score=22.0]; MalT-like TPR region [PF17874.3, score=21.7]} {Human: ENSG00000032742, IFT88, intraflagellar transport 88, [RH, Score=867, Expect=0.0]} {Mouse: ENSMUSG00000040040, Ift88, intraflagellar transport 88, [RH, Score=908, Expect=0.0]} {Dmel: FBgn0016919, nompB, no mechanoreceptor potential B, [RH, Score=349, Expect=1e-107]} {Celegans: WBGene00003885, osm-5, OSM-5, [RH, Score=624, Expect=0.0]} {Smed: dd_Smed_v6_5484_0_1, dd_Smed_v6_5484_0_1, [RH, Score=976, Expect=0.0]} {RNA1509_34996, RNA1509_4056} {RNA1310_1829, RNA1509_34996, RNA1509_4056} {RNA1509_34996, RNA1509_4056, RNA815_705}
28. MligTC455_26817 353 7.36 Mlig455_062943

Neo: -

Age: logFC(26M/2M)=-0.515

 TTLL10 1.789 - - - 0.832 0.957 - Mlig455_062943 {REF} {Length: 3909} {Pfam: Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=21.8]} {Human: ENSG00000162571, TTLL10, tubulin tyrosine ligase like 10, [Score=69.7, Expect=2e-12]} {Mouse: ENSMUSG00000029074, Ttll10, tubulin tyrosine ligase-like family, member 10, [Score=58.2, Expect=8e-09]} {Smed: dd_Smed_v6_9664_0_1, dd_Smed_v6_9664_0_1, [Score=87.4, Expect=9e-19]} {RNA1509_23478} {RNA1310_12709.1} {RNA815_2937}
29. MligTC455_49143 772 16.08 Mlig455_021704

Neo: -

Age: -

Region-enriched R2: 1.427/0.03420

 1.768 - - - 0.818 0.950 - Mlig455_021704 {REF} {Length: 2489} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=48.8]} {Smed: dd_Smed_v6_13233_0_2, dd_Smed_v6_13233_0_2, [Score=60.1, Expect=4e-09]} {RNA1509_11962} {RNA1310_8951.1, RNA1509_11962}
30. MligTC455_52549 150 3.12 Mlig455_002138, Mlig455_002284

Neo: -

Age: -

Regeneration-depleted BL: -6.786
Regeneration-depleted TP: -4.939

 1.756 - - - - 0.962 0.794

Mlig455_002138 {REF} {Length: 4372} {Pfam: Innexin [PF00876.20, score=62.4]} {Smed: dd_Smed_v6_9861_0_1, dd_Smed_v6_9861_0_1, [Score=60.1, Expect=9e-10]} {RNA1509_36214} {RNA1310_17023} {RNA815_33132}

Mlig455_002284 {REF} {Length: 2783} {Pfam: Innexin [PF00876.20, score=63.0]} {Smed: dd_Smed_v6_9861_0_1, dd_Smed_v6_9861_0_1, [Score=61.2, Expect=4e-10]} {RNA1509_36214} {RNA1310_17023} {RNA815_33132}
31. MligTC455_22682 782 16.28 Mlig455_006226

Neo: -

Age: Down-Up-Down

 PDE8B 1.747 0.788 - - 0.959 - - Mlig455_006226 {REF} {Length: 5356} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=282.4]; PAS domain [PF13426.9, score=46.9]; PAS fold [PF08448.12, score=37.2]; PAS fold [PF08447.14, score=35.4]; PAS fold [PF00989.27, score=34.8]} {Human: ENSG00000113231, PDE8B, phosphodiesterase 8B, [RH, Score=655, Expect=0.0]; ENSG00000284762, AC022414.1, phosphodiesterase 8B, [RH, Score=654, Expect=0.0]; ENSG00000073417, PDE8A, phosphodiesterase 8A, [RH, Score=641, Expect=0.0]} {Mouse: ENSMUSG00000021684, Pde8b, phosphodiesterase 8B, [RH, Score=659, Expect=0.0]} {Dmel: FBgn0266377, Pde8, Phosphodiesterase 8, [RH, Score=442, Expect=1e-142]} {Celegans: WBGene00022389, pde-6, Probable 3',5'-cyclic phosphodiesterase pde-6, [RH, Score=307, Expect=2e-92]} {Smed: dd_Smed_v6_10593_0_1, dd_Smed_v6_10593_0_1, [RH, Score=474, Expect=5e-155]} {RNA1509_36096, RNA1509_44408, RNA1509_54068} {RNA1310_2301, RNA1509_44408, RNA1509_54068} {RNA1509_44408, RNA1509_54068, RNA815_483.1}
32. MligTC455_45892 26 0.54 Mlig455_024234

Neo: -

Age: -

 HTR3A 1.734 - - - - 0.982 0.752 Mlig455_024234 {REF} {Length: 1801} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=107.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=73.5]} {Human: ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=139, Expect=6e-36]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=137, Expect=3e-35]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=135, Expect=1e-34]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=137, Expect=1e-35]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=136, Expect=4e-35]; ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=134, Expect=2e-34]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=122, Expect=5e-30]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=140, Expect=2e-36]} {Smed: dd_Smed_v6_12182_0_1, dd_Smed_v6_12182_0_1, [Score=130, Expect=3e-33]} {RNA1509_7752} {RNA1310_10606.2} {RNA815_50031}
33. MligTC455_41199 7523 156.73 Mlig455_001888, Mlig455_048783

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.793

 CFAP45 1.73 - - - - 0.952 0.778

Mlig455_001888 {REF} {Length: 2583} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=192.2]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [Score=301, Expect=2e-95]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [Score=296, Expect=2e-93]} {Dmel: FBgn0037162, CG11449, [Score=100, Expect=4e-22]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [Score=407, Expect=1e-136]} {RNA1509_2741} {RNA1310_7881.1} {RNA815_2376.1}

Mlig455_048783 {REF} {Length: 2929} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=268.3]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [RH, Score=371, Expect=6e-122]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [RH, Score=365, Expect=9e-120]} {Dmel: FBgn0037162, CG11449, [RH, Score=116, Expect=2e-27]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [RH, Score=478, Expect=5e-164]} {RNA1509_11068, RNA1509_22358, RNA1509_2741, RNA1509_455} {RNA1310_7881.1, RNA1509_11068, RNA1509_22358, RNA1509_2741} {RNA1509_11068, RNA1509_22358, RNA1509_2741, RNA815_2376.1}
34. MligTC455_37901 335 6.98 Mlig455_056248

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.829

 1.724 - 0.953 - - 0.771 - Mlig455_056248 {REF} {Length: 2926} {RNA1509_51793, RNA1509_6108} {RNA1310_13444.1, RNA1509_51793, RNA1509_6108} {RNA1509_51793, RNA1509_6108, RNA815_4706.1}
35. MligTC455_05889 28 0.58 Mlig455_027604, Mlig455_047689, Mlig455_047690

Neo: -

Age: -

 TLR4 1.722 - - - - 0.957 0.765

Mlig455_027604 {REF} {Length: 3445} {Pfam: Leucine rich repeat [PF13855.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=38.2]; TIR domain [PF01582.22, score=31.9]; TIR domain [PF13676.8, score=24.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=21.4]} {Human: ENSG00000136869, TLR4, toll like receptor 4, [RH, Score=74.3, Expect=6e-13]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [Score=60.1, Expect=1e-08]; ENSMUSG00000030600, Lrfn1, leucine rich repeat and fibronectin type III domain containing 1, [Score=59.3, Expect=2e-08]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=58.5, Expect=4e-08]} {Dmel: FBgn0036494, Toll-6, [Score=80.5, Expect=4e-15]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=50.4, Expect=6e-06]} {RNA1310_7084} {RNA815_22808}

Mlig455_047689 {REF} {Length: 352} {Pfam: Leucine rich repeat [PF13855.8, score=35.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=20.6]} {RNA1310_7084} {RNA815_47088}

Mlig455_047690 {REF} {Length: 346} {Pfam: Leucine rich repeat [PF13855.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=38.2]; TIR domain [PF01582.22, score=31.9]; TIR domain [PF13676.8, score=24.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=21.4]} {Human: ENSG00000136869, TLR4, toll like receptor 4, [RH, Score=74.3, Expect=6e-13]} {Mouse: ENSMUSG00000031558, Slit2, slit guidance ligand 2, [Score=60.1, Expect=1e-08]; ENSMUSG00000030600, Lrfn1, leucine rich repeat and fibronectin type III domain containing 1, [Score=59.3, Expect=2e-08]; ENSMUSG00000056427, Slit3, slit guidance ligand 3, [Score=58.5, Expect=4e-08]} {Dmel: FBgn0036494, Toll-6, [Score=80.5, Expect=4e-15]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=50.4, Expect=6e-06]} {RNA1310_7084} {RNA815_47699}
36. MligTC455_39941 9459 197.06 Mlig455_063449, Mlig455_063484

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.626

 1.701 - - - 0.955 - 0.746

Mlig455_063449 {REF} {Length: 721} {RNA1509_60047} {RNA1310_34704} {RNA815_21539.1}

Mlig455_063484 {REF} {Length: 862} {RNA1509_60047} {RNA1310_34704} {RNA815_21539.1}
37. MligTC455_22683 1080 22.51 Mlig455_006288

Neo: -

Age: Down-Up-Down

 PDE8A 1.698 - - - 0.968 0.730 - Mlig455_006288 {REF} {Length: 3418} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=283.6]; PAS domain [PF13426.9, score=37.0]; PAS fold [PF08447.14, score=36.0]; PAS fold [PF00989.27, score=28.3]; PAS fold [PF08448.12, score=28.0]} {Human: ENSG00000073417, PDE8A, phosphodiesterase 8A, [Score=561, Expect=0.0]; ENSG00000113231, PDE8B, phosphodiesterase 8B, [Score=554, Expect=0.0]; ENSG00000284762, AC022414.1, phosphodiesterase 8B, [Score=553, Expect=0.0]} {Mouse: ENSMUSG00000021684, Pde8b, phosphodiesterase 8B, [Score=557, Expect=0.0]; ENSMUSG00000025584, Pde8a, phosphodiesterase 8A, [Score=545, Expect=0.0]} {Dmel: FBgn0266377, Pde8, Phosphodiesterase 8, [Score=388, Expect=4e-124]} {Celegans: WBGene00022389, pde-6, Probable 3',5'-cyclic phosphodiesterase pde-6, [RH, Score=306, Expect=1e-93]} {Smed: dd_Smed_v6_10593_0_1, dd_Smed_v6_10593_0_1, [RH, Score=454, Expect=2e-149]} {RNA1509_1517} {RNA1310_2301} {RNA815_483.1}
38. MligTC455_42746 483 10.06 Mlig455_040721

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.368

 ACSF2 1.695 - - - 0.952 0.743 - Mlig455_040721 {REF} {Length: 3197} {Pfam: AMP-binding enzyme [PF00501.30, score=314.2]; AMP-binding enzyme C-terminal domain [PF13193.8, score=37.2]} {Human: ENSG00000167107, ACSF2, acyl-CoA synthetase family member 2, [Score=147, Expect=1e-37]} {Mouse: ENSMUSG00000076435, Acsf2, acyl-CoA synthetase family member 2, [Score=156, Expect=8e-41]} {Dmel: FBgn0027601, pdgy, pudgy, [Score=269, Expect=8e-83]} {Celegans: WBGene00008669, acs-14, Fatty Acid CoA Synthetase family, [Score=259, Expect=1e-79]} {Smed: dd_Smed_v6_10135_0_1, dd_Smed_v6_10135_0_1, [Score=317, Expect=5e-102]} {RNA1509_22715} {RNA1310_10057.2} {RNA815_14069}
39. MligTC455_15189 30 0.63 Mlig455_068662

Neo: -

Age: -

 1.687 - - - - 0.967 0.720 Mlig455_068662 {REF} {Length: 1194} {Pfam: Cupin-like domain [PF13621.8, score=39.8]} {Dmel: FBgn0038510, CG14331, [Score=148, Expect=1e-41]} {Celegans: WBGene00004205, psr-1, Bifunctional arginine demethylase and lysyl-hydroxylase psr-1, [Score=49.7, Expect=1e-06]} {Smed: dd_Smed_v6_8235_0_1, dd_Smed_v6_8235_0_1, [Score=139, Expect=5e-38]} {RNA1509_3781} {RNA1310_5604.1} {RNA815_2493.1}
40. MligTC455_48454 602 12.54 Mlig455_041932

Neo: -

Age: Down-Up-Down

 CCDC154 1.682 - - 0.957 0.725 - - Mlig455_041932 {REF} {Length: 4159} {Pfam: Coiled-coil domain-containing protein 154 [PF15450.8, score=111.7]} {Human: ENSG00000197599, CCDC154, coiled-coil domain containing 154, [Score=94.7, Expect=2e-19]} {Mouse: ENSMUSG00000059562, Ccdc154, coiled-coil domain containing 154, [Score=86.3, Expect=5e-17]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=51.2, Expect=3e-06]} {Smed: dd_Smed_v6_10236_0_1, dd_Smed_v6_10236_0_1, [Score=407, Expect=1e-131]} {RNA1509_37351, RNA1509_5383} {RNA1310_2073.1, RNA1509_37351, RNA1509_5383} {RNA1509_37351, RNA1509_5383, RNA815_2050}
41. MligTC455_34559 580 12.07 Mlig455_066815

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.459

 GSTA2 1.661 - 0.702 - 0.959 - - Mlig455_066815 {REF} {Length: 1741} {Pfam: Glutathione S-transferase, N-terminal domain [PF02798.22, score=40.7]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=27.2]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=27.1]} {Human: ENSG00000244067, GSTA2, glutathione S-transferase alpha 2, [Score=66.6, Expect=8e-13]; ENSG00000243955, GSTA1, glutathione S-transferase alpha 1, [Score=64.7, Expect=3e-12]} {Mouse: ENSMUSG00000032348, Gsta4, glutathione S-transferase, alpha 4, [RH, Score=58.9, Expect=4e-11]} {Dmel: FBgn0010226, GstS1, Glutathione S transferase S1, [Score=66.6, Expect=5e-13]} {Celegans: WBGene00001786, gst-38, Glutathione S-Transferase, [Score=65.1, Expect=8e-13]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=95.1, Expect=3e-24]} {RNA1509_50934} {RNA1310_26310, RNA1509_50934} {RNA1509_50934, RNA815_40328}
42. MligTC455_49723 75 1.56 Mlig455_034028, Mlig455_060405

Neo: -

Age: -

 CALM1 1.65 - - - 0.950 0.700 -

Mlig455_034028 {REF} {Length: 673} {Pfam: EF-hand domain pair [PF13499.8, score=46.6]; EF-hand domain pair [PF13833.8, score=32.1]; EF-hand domain [PF13405.8, score=30.9]; EF hand [PF00036.34, score=29.5]} {Human: ENSG00000198668, CALM1, calmodulin 1, [Score=77.8, Expect=2e-17]; ENSG00000160014, CALM3, calmodulin 3, [Score=77.8, Expect=2e-17]; ENSG00000143933, CALM2, calmodulin 2, [Score=77.8, Expect=2e-17]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=77.8, Expect=1e-17]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=77.8, Expect=1e-17]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=77.8, Expect=1e-17]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=77.0, Expect=1e-17]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=77.0, Expect=1e-17]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=77.0, Expect=8e-18]} {RNA1310_38691} {RNA815_34059}

Mlig455_060405 {REF} {Length: 968} {Pfam: EF-hand domain pair [PF13499.8, score=46.6]; EF-hand domain pair [PF13833.8, score=32.1]; EF-hand domain [PF13405.8, score=30.9]; EF hand [PF00036.34, score=29.5]} {Human: ENSG00000198668, CALM1, calmodulin 1, [Score=77.8, Expect=2e-17]; ENSG00000160014, CALM3, calmodulin 3, [Score=77.8, Expect=2e-17]; ENSG00000143933, CALM2, calmodulin 2, [Score=77.8, Expect=2e-17]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=77.8, Expect=1e-17]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=77.8, Expect=1e-17]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=77.8, Expect=1e-17]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=77.0, Expect=1e-17]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=77.0, Expect=1e-17]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=77.0, Expect=8e-18]} {RNA1310_38691} {RNA815_34059}
43. MligTC455_34791 363 7.55 Mlig455_023393

Neo: -

Age: Down-Up-Up

 0.976 - - - - 0.976 - Mlig455_023393 {REF} {Length: 2051} {Smed: dd_Smed_v6_27312_0_1, dd_Smed_v6_27312_0_1, [Score=95.5, Expect=2e-20]} {RNA1509_6675} {RNA1310_2307} {RNA815_650}
44. MligTC455_29296 451 9.39 Mlig455_033882

Neo: -

Age: -

Region-enriched R2: 2.069/0.00679

 0.972 - - - 0.972 - - Mlig455_033882 {REF} {Length: 400} {NoTransDecoderORF} {RNA1509_17728} {RNA1310_48181} {RNA815_50465}
45. MligTC455_07563 21 0.43 Mlig455_045090

Neo: -

Age: -

 0.965 - - - - 0.965 - Mlig455_045090 {REF} {Length: 953} {NoTransDecoderORF}
46. MligTC455_29297 533 11.1 Mlig455_033889

Neo: -

Age: Up-Down-Up

Region-enriched R2: 2.005/0.00703

 0.965 - - - 0.965 - - Mlig455_033889 {REF} {Length: 4369} {TRANSSPLICED} {Pfam: Phage integrase family [PF00589.24, score=26.0]} {RNA1509_19505, RNA1509_60118} {RNA1310_1707, RNA1509_19505, RNA1509_60118} {RNA1509_19505, RNA1509_60118, RNA815_3378}
47. MligTC455_09325 11 0.23 Mlig455_047047

Neo: -

Age: -

 0.962 - - - - 0.962 - Mlig455_047047 {REF} {Length: 475} {Pfam: Family of unknown function (DUF5358) [PF17311.4, score=20.5]} {RNA1509_14471} {RNA1310_54312} {RNA815_28165.2}
48. MligTC455_29298 448 9.33 Mlig455_054114

Neo: -

Age: -

Region-enriched R2: 1.919/0.01506

 0.961 - - - 0.961 - - Mlig455_054114 {REF} {Length: 1799} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=39.1]} {Smed: dd_Smed_v6_13661_0_2, dd_Smed_v6_13661_0_2, [Score=171, Expect=3e-51]} {RNA1509_30304} {RNA1310_26220.2} {RNA815_9613}
49. MligTC455_29904 179 3.73 Mlig455_047055

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.696

 MAP3K4 0.961 - - - - 0.961 - Mlig455_047055 {REF} {Length: 3991} {Pfam: Protein kinase domain [PF00069.27, score=316.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=241.4]; Fungal protein kinase [PF17667.3, score=53.7]; ABC1 atypical kinase-like domain [PF03109.18, score=35.6]; Phosphotransferase enzyme family [PF01636.25, score=34.3]; Ankyrin repeat [PF13606.8, score=24.2]; Kinase-like [PF14531.8, score=24.2]; Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ternary complex associated domain 9 [PF19974.1, score=22.5]; Seadornavirus VP7 [PF07387.13, score=20.7]; Ankyrin repeat [PF00023.32, score=20.0]; Ankyrin repeats (many copies) [PF13857.8, score=19.9]; Choline/ethanolamine kinase [PF01633.22, score=18.5]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=132, Expect=5e-31]; ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=127, Expect=2e-30]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=132, Expect=5e-32]; ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=128, Expect=7e-30]} {Dmel: FBgn0024329, Mekk1, [Score=124, Expect=2e-28]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=129, Expect=2e-30]} {Smed: dd_Smed_v6_9379_0_2, dd_Smed_v6_9379_0_2, [Score=121, Expect=2e-28]} {RNA1509_39395} {RNA1310_23280} {RNA815_6977.2}
50. MligTC455_39743 344 7.17 Mlig455_034482

Neo: -

Age: -

 AGBL4 0.956 - - - 0.956 - - Mlig455_034482 {REF} {Length: 2111} {Pfam: Zinc carboxypeptidase [PF00246.26, score=93.1]; Cytosolic carboxypeptidase N-terminal domain [PF18027.3, score=51.5]} {Human: ENSG00000186094, AGBL4, ATP/GTP binding protein like 4, [RH, Score=672, Expect=0.0]} {Mouse: ENSMUSG00000061298, Agbl4, ATP/GTP binding protein-like 4, [RH, Score=675, Expect=0.0]} {Dmel: FBgn0051019, CG31019, [RH, Score=462, Expect=1e-157]} {Celegans: WBGene00017136, ccpp-6, Cytosolic carboxypeptidase 6, [RH, Score=407, Expect=1e-138]} {Smed: dd_Smed_v6_12533_0_1, dd_Smed_v6_12533_0_1, [RH, Score=684, Expect=0.0]} {RNA1509_7431} {RNA1310_10629, RNA1509_7431} {RNA1509_7431, RNA815_5302.1}
51. MligTC455_49484 10996 229.08 Mlig455_045342

Neo: -

Age: logFC(26M/2M)=-0.289

Region-enriched R2: 1.032/0.00001

 PCCB 0.956 - - - - 0.956 - Mlig455_045342 {REF} {Length: 2338} {TRANSSPLICED} {Pfam: Carboxyl transferase domain [PF01039.24, score=621.7]; Malonate decarboxylase gamma subunit (MdcE) [PF06833.13, score=25.8]} {Human: ENSG00000114054, PCCB, propionyl-CoA carboxylase subunit beta, [RH, Score=789, Expect=0.0]} {Mouse: ENSMUSG00000032527, Pccb, propionyl Coenzyme A carboxylase, beta polypeptide, [RH, Score=785, Expect=0.0]} {Dmel: FBgn0042083, CG3267, [Score=235, Expect=6e-70]} {Celegans: WBGene00018701, pccb-1, Propionyl Coenzyme A Carboxylase Beta subunit, [RH, Score=785, Expect=0.0]} {Smed: dd_Smed_v6_513_0_1, dd_Smed_v6_513_0_1, [RH, Score=839, Expect=0.0]} {RNA1509_1631, RNA1509_328} {RNA1310_10357.1, RNA1509_1631} {RNA1509_1631, RNA815_3334.1}
52. MligTC455_50014 27 0.56 Mlig455_003397

Neo: -

Age: -

Region-enriched R2: 6.842/0.00677

 0.955 - - - - 0.955 - Mlig455_003397 {REF} {Length: 602} {NoTransDecoderORF} {RNA1310_99134}
53. MligTC455_34894 588 12.26 Mlig455_026735, Mlig455_051722, Mlig455_051745

Neo: -

Age: logFC(26M/2M)=-0.370

 PLA2G4A 0.954 - - - - 0.954 -

Mlig455_026735 {REF} {Length: 3880} {Pfam: Lysophospholipase catalytic domain [PF01735.20, score=217.8]; C2 domain [PF00168.32, score=48.4]} {Human: ENSG00000116711, PLA2G4A, phospholipase A2 group IVA, [RH, Score=383, Expect=5e-118]} {Mouse: ENSMUSG00000056220, Pla2g4a, phospholipase A2, group IVA (cytosolic, calcium-dependent), [RH, Score=385, Expect=5e-119]} {RNA1509_14556} {RNA1310_2849} {RNA815_1078}

Mlig455_051722 {REF} {Length: 3259} {Pfam: Lysophospholipase catalytic domain [PF01735.20, score=188.8]} {Human: ENSG00000116711, PLA2G4A, phospholipase A2 group IVA, [Score=268, Expect=3e-77]} {Mouse: ENSMUSG00000056220, Pla2g4a, phospholipase A2, group IVA (cytosolic, calcium-dependent), [Score=268, Expect=3e-77]} {RNA1509_14556} {RNA1310_2849} {RNA815_1078}

Mlig455_051745 {REF} {Length: 3648} {Pfam: Lysophospholipase catalytic domain [PF01735.20, score=217.8]; C2 domain [PF00168.32, score=35.5]} {Human: ENSG00000116711, PLA2G4A, phospholipase A2 group IVA, [Score=350, Expect=7e-106]} {Mouse: ENSMUSG00000056220, Pla2g4a, phospholipase A2, group IVA (cytosolic, calcium-dependent), [Score=349, Expect=9e-106]} {RNA1509_14556} {RNA1310_2849} {RNA815_1078}
54. MligTC455_49485 10924 227.58 Mlig455_045426

Neo: -

Age: logFC(26M/2M)=-0.286

Region-enriched R2: 1.070/0.00000

 PCCB 0.953 - - - - 0.953 - Mlig455_045426 {REF} {Length: 1500} {Pfam: Carboxyl transferase domain [PF01039.24, score=326.0]; Malonate decarboxylase gamma subunit (MdcE) [PF06833.13, score=24.8]} {Human: ENSG00000114054, PCCB, propionyl-CoA carboxylase subunit beta, [Score=393, Expect=8e-137]} {Mouse: ENSMUSG00000032527, Pccb, propionyl Coenzyme A carboxylase, beta polypeptide, [Score=393, Expect=7e-136]} {Dmel: FBgn0042083, CG3267, [Score=122, Expect=1e-31]} {Celegans: WBGene00018701, pccb-1, Propionyl Coenzyme A Carboxylase Beta subunit, [Score=385, Expect=4e-133]} {Smed: dd_Smed_v6_513_0_1, dd_Smed_v6_513_0_1, [Score=428, Expect=2e-149]} {RNA1509_1810} {RNA1310_10357.1} {RNA815_3334.1}
55. MligTC455_22031 14 0.29 Mlig455_010391

Neo: -

Age: -

 0.951 - - - - 0.951 - Mlig455_010391 {REF} {Length: 1844} {Pfam: Histone H1-like nucleoprotein HC2 [PF07382.13, score=49.0]} {RNA1310_59482} {RNA815_41482}
56. MligTC455_09665 25 0.53 Mlig455_062716

Neo: -

Age: -

 0.95 - - - - 0.950 - Mlig455_062716 {REF} {Length: 350} {NoTransDecoderORF} {RNA1509_9137} {RNA1310_83652} {RNA815_6842}
57. MligTC455_40795 354 7.37 Mlig455_058935

Neo: -

Age: Down-Up-Down

 MARCH8 0.95 - - - 0.950 - - Mlig455_058935 {REF} {Length: 2270} {TRANSSPLICED} {Pfam: RING-variant domain [PF12906.9, score=43.6]} {Human: ENSG00000165406, MARCH8, membrane associated ring-CH-type finger 8, [Score=48.9, Expect=7e-06]; ENSG00000278545, MARCH8, membrane associated ring-CH-type finger 8, [Score=48.5, Expect=7e-06]} {Mouse: ENSMUSG00000025702, March8, membrane-associated ring finger (C3HC4) 8, [Score=48.5, Expect=5e-06]} {Dmel: FBgn0035983, CG4080, [Score=52.0, Expect=7e-07]} {RNA1509_38482, RNA1509_39355} {RNA1310_22099.1, RNA1509_38482, RNA1509_39355} {RNA1509_38482, RNA1509_39355, RNA815_10655}

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