Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_22897 | 1057 | 22.03 | Mlig455_064864 | Neo: - Age: Up-Down-Down |
LCA5 | Mlig455_064864 {REF} {Length: 4344} {TRANSSPLICED} {Pfam: Ciliary protein causing Leber congenital amaurosis disease [PF15619.8, score=143.2]} {Human: ENSG00000135338, LCA5, LCA5, lebercilin, [RH, Score=107, Expect=2e-23]} {Mouse: ENSMUSG00000032258, Lca5, Leber congenital amaurosis 5 (human), [RH, Score=104, Expect=1e-22]} {Dmel: FBgn0036687, CG6652, [RH, Score=53.1, Expect=8e-07]} {Smed: dd_Smed_v6_14572_0_1, dd_Smed_v6_14572_0_1, [RH, Score=101, Expect=5e-22]} {RNA1509_3039} {RNA1310_7273} {RNA815_3712} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 0.294 | 4.771 | 0.71169 | 1.00000 | |
RegionR2 | 0.578 | 4.771 | 0.10133 | 0.39168 | |
RegionR3 | 0.409 | 4.771 | 0.12177 | 0.60319 | |
RegionR4 | -0.104 | 4.771 | 0.76935 | 1.00000 | |
RegionR5 | -0.416 | 4.771 | 0.10579 | 0.31699 | |
RegionR6 | -0.346 | 4.771 | 0.23577 | 0.81945 | |
RegionR7 | -0.336 | 4.771 | 0.38767 | 1.00000 | |
RegionR8 | -0.079 | 4.771 | 0.86254 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -1.559 | 4.771 | 0.29236 | 0.99028 | |
RegenerationR2 | 0.274 | 4.771 | 0.31420 | 0.75344 | |
RegenerationR3 | 0.043 | 4.771 | 0.89185 | 1.00000 | |
RegenerationR4 | -0.005 | 4.771 | 0.98767 | 1.00000 | |
RegenerationR5 | 0.191 | 4.771 | 0.54172 | 0.88114 | |
RegenerationR6 | -0.323 | 4.771 | 0.37148 | 0.71447 | |
RegenerationBL | 0.421 | 4.771 | 0.30269 | 0.66627 | |
RegenerationTP | -0.01 | 4.771 | 0.98129 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_22897 | 1057 | 22.03 | Mlig455_064864 | Neo: - Age: Up-Down-Down |
LCA5 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_064864 {REF} {Length: 4344} {TRANSSPLICED} {Pfam: Ciliary protein causing Leber congenital amaurosis disease [PF15619.8, score=143.2]} {Human: ENSG00000135338, LCA5, LCA5, lebercilin, [RH, Score=107, Expect=2e-23]} {Mouse: ENSMUSG00000032258, Lca5, Leber congenital amaurosis 5 (human), [RH, Score=104, Expect=1e-22]} {Dmel: FBgn0036687, CG6652, [RH, Score=53.1, Expect=8e-07]} {Smed: dd_Smed_v6_14572_0_1, dd_Smed_v6_14572_0_1, [RH, Score=101, Expect=5e-22]} {RNA1509_3039} {RNA1310_7273} {RNA815_3712} |
2. | MligTC455_23545 | 337 | 7.02 | Mlig455_021926 | Neo: - Age: - |
MAP3K19 | 2.575 | - | 0.709 | 0.954 | - | - | 0.912 | Mlig455_021926 {REF} {Length: 5795} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=189.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=145.7]; Ankyrin repeats (3 copies) [PF12796.9, score=111.3]; Ankyrin repeats (many copies) [PF13637.8, score=88.9]; Ankyrin repeats (many copies) [PF13857.8, score=82.7]; Ankyrin repeat [PF00023.32, score=61.1]; Ankyrin repeat [PF13606.8, score=59.7]; ABC1 atypical kinase-like domain [PF03109.18, score=31.6]; Fungal protein kinase [PF17667.3, score=17.8]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=165, Expect=3e-43]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=169, Expect=3e-43]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=145, Expect=4e-36]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=136, Expect=2e-33]} {Smed: dd_Smed_v6_10339_0_1, dd_Smed_v6_10339_0_1, [Score=154, Expect=1e-38]} {RNA1509_9426} {RNA1310_9191} {RNA815_12161} |
3. | MligTC455_41632 | 1020 | 21.26 | Mlig455_031169 | Neo: - Age: - |
IQUB | 2.574 | 0.760 | - | - | 0.854 | - | 0.960 | Mlig455_031169 {REF} {Length: 3147} {TRANSSPLICED} {Pfam: Ubiquitin family [PF00240.25, score=29.5]} {Human: ENSG00000164675, IQUB, IQ motif and ubiquitin domain containing, [RH, Score=582, Expect=0.0]} {Mouse: ENSMUSG00000046192, Iqub, IQ motif and ubiquitin domain containing, [RH, Score=545, Expect=0.0]} {Dmel: FBgn0038960, CG13855, [RH, Score=241, Expect=2e-68]} {Smed: dd_Smed_v6_9227_0_1, dd_Smed_v6_9227_0_1, [RH, Score=585, Expect=0.0]} {RNA1509_27336, RNA1509_6305} {RNA1310_4747.1, RNA1509_27336, RNA1509_6305} {RNA1509_27336, RNA1509_6305, RNA815_1419.1} |
4. | MligTC455_47067 | 973 | 20.27 | Mlig455_008123 | Neo: - |
2.511 | - | 0.726 | - | 0.829 | - | 0.956 | Mlig455_008123 {REF} {Length: 1559} {Pfam: Cilia- and flagella-associated protein HOATZ-like [PF17664.3, score=53.1]} {RNA1509_14506, RNA1509_58252} {RNA1310_1256, RNA1509_14506, RNA1509_58252} {RNA1509_14506, RNA1509_58252, RNA815_9775.1} | |
5. | MligTC455_49005 | 642 | 13.37 | Mlig455_043634 | Neo: - Age: - |
CCDC180 | 2.462 | 0.738 | 0.774 | - | - | - | 0.950 | Mlig455_043634 {REF} {Length: 3450} {Pfam: Domain of unknown function (DUF4456) [PF14644.8, score=137.1]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [Score=160, Expect=2e-41]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [Score=110, Expect=3e-25]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [Score=166, Expect=4e-44]} {RNA1509_8832} {RNA1310_898.2} {RNA815_8511} |
6. | MligTC455_52859 | 1033 | 21.52 | Mlig455_049482 | Neo: - Age: logFC(26M/2M)=-0.394 |
EFCAB10 | 1.824 | - | - | - | 0.856 | - | 0.968 | Mlig455_049482 {REF} {Length: 648} {TRANSSPLICED} {Pfam: Family of unknown function (DUF5582) [PF17819.3, score=26.3]; Family of unknown function (DUF5586) [PF17824.3, score=24.5]} {Human: ENSG00000185055, EFCAB10, EF-hand calcium binding domain 10, [RH, Score=88.6, Expect=4e-23]} {Mouse: ENSMUSG00000020562, Efcab10, EF-hand calcium binding domain 10, [RH, Score=92.8, Expect=7e-25]} {Smed: dd_Smed_v6_6477_0_1, dd_Smed_v6_6477_0_1, [RH, Score=114, Expect=2e-33]} {RNA1509_32720} {RNA1310_54125.2, RNA1509_32720} {RNA1509_32720, RNA815_27872} |
7. | MligTC455_32265 | 915 | 19.06 | Mlig455_041418 | Neo: - Age: logFC(26M/2M)=-0.513 |
DCDC2 | 1.822 | - | - | - | 0.869 | - | 0.953 | Mlig455_041418 {REF} {Length: 2999} {Pfam: Doublecortin [PF03607.19, score=82.8]; IQ calmodulin-binding motif [PF00612.29, score=68.9]} {Human: ENSG00000146038, DCDC2, doublecortin domain containing 2, [RH, Score=105, Expect=2e-23]} {Mouse: ENSMUSG00000035910, Dcdc2a, doublecortin domain containing 2a, [RH, Score=111, Expect=2e-25]} {Dmel: FBgn0013467, igl, igloo, [Score=50.8, Expect=1e-06]} {Smed: dd_Smed_v6_6464_0_1, dd_Smed_v6_6464_0_1, [Score=243, Expect=3e-70]} {RNA1509_53513, RNA1509_5661} {RNA1310_18305, RNA1509_53513} {RNA1509_53513, RNA815_9800.1} |
8. | MligTC455_38137 | 2605 | 54.28 | Mlig455_040033 | Neo: - Age: - |
TCTEX1D1 | 1.784 | - | 0.828 | - | - | - | 0.956 | Mlig455_040033 {REF} {Length: 899} {Pfam: Tctex-1 family [PF03645.15, score=71.6]} {Human: ENSG00000152760, TCTEX1D1, Tctex1 domain containing 1, [Score=75.1, Expect=7e-17]; ENSG00000213123, TCTEX1D2, Tctex1 domain containing 2, [Score=74.7, Expect=3e-17]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [Score=87.0, Expect=9e-22]} {Dmel: FBgn0037773, CG5359, [Score=50.4, Expect=4e-08]} {Smed: dd_Smed_v6_9321_0_2, dd_Smed_v6_9321_0_2, [Score=78.2, Expect=1e-18]} {RNA1509_7075} {RNA1310_45569, RNA1509_7075} {RNA1509_7075, RNA815_23689} |
9. | MligTC455_54146 | 1239 | 25.82 | Mlig455_049378 | Neo: - |
DRC7 | 1.748 | - | - | - | 0.793 | - | 0.955 | Mlig455_049378 {REF} {Length: 3401} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=19.6]} {Human: ENSG00000159625, DRC7, dynein regulatory complex subunit 7, [RH, Score=736, Expect=0.0]} {Mouse: ENSMUSG00000031786, Drc7, dynein regulatory complex subunit 7, [RH, Score=728, Expect=0.0]} {Dmel: FBgn0083946, lobo, lost boys, [RH, Score=280, Expect=4e-80]} {Smed: dd_Smed_v6_12588_0_1, dd_Smed_v6_12588_0_1, [RH, Score=708, Expect=0.0]} {RNA1509_1230} {RNA1310_4483} {RNA815_1294} |
10. | MligTC455_38136 | 2459 | 51.22 | Mlig455_015043 | Neo: - Age: - Region-enriched R4: 1.060/0.04586 |
TCTEX1D1 | 1.743 | - | 0.786 | - | - | - | 0.957 | Mlig455_015043 {REF} {Length: 905} {Pfam: Tctex-1 family [PF03645.15, score=71.9]} {Human: ENSG00000152760, TCTEX1D1, Tctex1 domain containing 1, [Score=76.3, Expect=2e-17]; ENSG00000213123, TCTEX1D2, Tctex1 domain containing 2, [Score=73.9, Expect=8e-17]} {Mouse: ENSMUSG00000028523, Tctex1d1, Tctex1 domain containing 1, [Score=88.6, Expect=2e-22]} {Dmel: FBgn0037773, CG5359, [Score=50.1, Expect=7e-08]} {Smed: dd_Smed_v6_9321_0_2, dd_Smed_v6_9321_0_2, [Score=77.8, Expect=2e-18]} {RNA1509_11271, RNA1509_7075} {RNA1310_45569, RNA1509_11271} {RNA1509_11271, RNA815_23689} |
11. | MligTC455_11545 | 575 | 11.98 | Mlig455_028030 | Neo: - Age: - |
1.737 | - | - | - | 0.782 | - | 0.955 | Mlig455_028030 {REF} {Length: 5018} {TRANSSPLICED} {Smed: dd_Smed_v6_12364_0_1, dd_Smed_v6_12364_0_1, [RH, Score=485, Expect=7e-150]} {RNA1509_11986} {RNA1310_1255.1} {RNA815_6764} | |
12. | MligTC455_17334 | 675 | 14.07 | Mlig455_059525 | Neo: - Age: - Region-enriched R2: 2.261/0.00001 |
CFAP77 | 1.737 | - | - | - | 0.786 | - | 0.951 | Mlig455_059525 {REF} {Length: 3318} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4483) [PF14825.8, score=38.2]} {Human: ENSG00000188523, CFAP77, cilia and flagella associated protein 77, [Score=65.1, Expect=1e-11]} {Smed: dd_Smed_v6_5179_0_1, dd_Smed_v6_5179_0_1, [Score=63.5, Expect=6e-12]} {RNA1509_11420, RNA1509_21534} {RNA1310_11821, RNA1509_11420, RNA1509_21534} {RNA1509_11420, RNA1509_21534, RNA815_16183} |
13. | MligTC455_22551 | 1093 | 22.77 | Mlig455_000648 | Neo: - Age: - |
NR5A2 | 1.71 | - | - | 0.950 | 0.760 | - | - | Mlig455_000648 {REF} {Length: 2948} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=47.6]} {Human: ENSG00000116833, NR5A2, nuclear receptor subfamily 5 group A member 2, [Score=60.8, Expect=2e-09]; ENSG00000151623, NR3C2, nuclear receptor subfamily 3 group C member 2, [Score=59.3, Expect=1e-08]; ENSG00000132170, PPARG, peroxisome proliferator activated receptor gamma, [Score=58.2, Expect=1e-08]; ENSG00000119508, NR4A3, nuclear receptor subfamily 4 group A member 3, [Score=57.8, Expect=2e-08]} {Mouse: ENSMUSG00000031618, Nr3c2, nuclear receptor subfamily 3, group C, member 2, [Score=59.7, Expect=5e-09]; ENSMUSG00000024431, Nr3c1, nuclear receptor subfamily 3, group C, member 1, [Score=59.3, Expect=5e-09]; ENSMUSG00000000440, Pparg, peroxisome proliferator activated receptor gamma, [Score=58.2, Expect=1e-08]; ENSMUSG00000026826, Nr4a2, nuclear receptor subfamily 4, group A, member 2, [Score=57.4, Expect=2e-08]; ENSMUSG00000028341, Nr4a3, nuclear receptor subfamily 4, group A, member 3, [Score=57.4, Expect=2e-08]} {Dmel: FBgn0004865, Eip78C, Ecdysone-induced protein 78C, [Score=60.8, Expect=1e-09]} {Celegans: WBGene00008778, nhr-264, Nuclear Hormone Receptor family, [RH, Score=70.9, Expect=3e-13]} {Smed: dd_Smed_v6_12229_0_1, dd_Smed_v6_12229_0_1, [Score=58.9, Expect=4e-09]} {RNA1509_11892} {RNA1310_16333.2, RNA1509_11892} {RNA1509_11892, RNA815_10785} |
14. | MligTC455_49636 | 558 | 11.63 | Mlig455_050883 | Neo: - Age: logFC(26M/2M)=0.482 |
WDR88 | 1.697 | - | - | - | 0.726 | - | 0.971 | Mlig455_050883 {REF} {Length: 1337} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=99.3]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=24.8]; WD40 region of Ge1, enhancer of mRNA-decapping protein [PF16529.7, score=21.6]} {Human: ENSG00000166359, WDR88, WD repeat domain 88, [RH, Score=246, Expect=2e-76]} {Mouse: ENSMUSG00000106911, Snrnp40, small nuclear ribonucleoprotein 40 (U5), [Score=122, Expect=8e-31]; ENSMUSG00000074088, Snrnp40, small nuclear ribonucleoprotein 40 (U5), [Score=122, Expect=8e-31]} {Dmel: FBgn0015754, Lis-1, Lissencephaly-1, [Score=90.1, Expect=2e-19]} {Celegans: WBGene00003047, lis-1, Lissencephaly-1 homolog, [Score=83.6, Expect=2e-17]} {Smed: dd_Smed_v6_12057_0_2, dd_Smed_v6_12057_0_2, [RH, Score=291, Expect=1e-95]} {RNA1509_14225} {RNA1310_25278} {RNA815_11177} |
15. | MligTC455_52109 | 297 | 6.19 | Mlig455_069072 | Neo: - |
0.973 | - | - | - | 0.973 | - | - | Mlig455_069072 {REF} {Length: 2302} {RNA1509_46495} {RNA1310_32026} {RNA815_11216.2} | |
16. | MligTC455_19229 | 3397 | 70.77 | Mlig455_003179, Mlig455_003381 | Neo: - Age: logFC(26M/2M)=-0.346 |
TCTE1 | 0.97 | - | - | - | - | - | 0.970 | Mlig455_003179 {REF} {Length: 2512} {Pfam: Leucine Rich repeat [PF13516.8, score=60.4]; Leucine Rich Repeat [PF00560.35, score=21.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=20.6]} {Human: ENSG00000146221, TCTE1, t-complex-associated-testis-expressed 1, [RH, Score=414, Expect=5e-140]} {Mouse: ENSMUSG00000023949, Tcte1, t-complex-associated testis expressed 1, [RH, Score=410, Expect=2e-138]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=54.3, Expect=2e-07]} {Smed: dd_Smed_v6_12524_0_1, dd_Smed_v6_12524_0_1, [RH, Score=477, Expect=4e-164]} {RNA1509_3507} {RNA1310_14006, RNA1509_3507} {RNA1509_3507, RNA815_5380} Mlig455_003381 {REF} {Length: 2163} {Pfam: Leucine Rich repeat [PF13516.8, score=60.4]; Leucine Rich Repeat [PF00560.35, score=21.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=20.6]} {Human: ENSG00000146221, TCTE1, t-complex-associated-testis-expressed 1, [RH, Score=415, Expect=4e-140]} {Mouse: ENSMUSG00000023949, Tcte1, t-complex-associated testis expressed 1, [RH, Score=410, Expect=2e-138]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=54.3, Expect=2e-07]} {Smed: dd_Smed_v6_12524_0_1, dd_Smed_v6_12524_0_1, [RH, Score=477, Expect=3e-164]} {RNA1509_3507, RNA1509_37235} {RNA1310_14006, RNA1509_37235} {RNA1509_37235, RNA815_5380} |
17. | MligTC455_32560 | 474 | 9.88 | Mlig455_005052 | Neo: - Age: - |
0.966 | - | - | - | - | - | 0.966 | Mlig455_005052 {REF} {Length: 3173} {Smed: dd_Smed_v6_9637_0_1, dd_Smed_v6_9637_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_2854} {RNA1310_3474} {RNA815_179} | |
18. | MligTC455_32561 | 507 | 10.57 | Mlig455_005261 | Neo: - Age: logFC(26M/2M)=-0.281 |
NWD2 | 0.961 | - | - | - | - | - | 0.961 | Mlig455_005261 {REF} {Length: 6130} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=172, Expect=3e-42]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=159, Expect=2e-38]} {Dmel: FBgn0038397, CG10185, [Score=226, Expect=3e-59]} {Celegans: WBGene00020254, T05C3.2, [Score=233, Expect=3e-61]} {Smed: dd_Smed_v6_9637_0_1, dd_Smed_v6_9637_0_1, [RH, Score=669, Expect=0.0]} {RNA1509_2854, RNA1509_32196, RNA1509_40786} {RNA1310_588, RNA1509_2854, RNA1509_32196, RNA1509_40786} {RNA1509_2854, RNA1509_32196, RNA1509_40786, RNA815_179} |
19. | MligTC455_52409 | 790 | 16.46 | Mlig455_031784 | Neo: - Age: Up-Down-Down Regeneration-upregulated R6: 1.928 Regeneration-enriched R6: 1.928 |
0.961 | - | - | - | - | - | 0.961 | Mlig455_031784 {REF} {Length: 5819} {TRANSSPLICED} {Dmel: FBgn0053196, dpy, dumpy, [Score=58.9, Expect=5e-08]} {RNA1509_1380, RNA1509_21392, RNA1509_45445} {RNA1310_585.1, RNA1509_1380, RNA1509_21392, RNA1509_45445} {RNA1509_1380, RNA1509_21392, RNA1509_45445, RNA815_122.1} | |
20. | MligTC455_30619 | 308 | 6.42 | Mlig455_058929 | Neo: - Age: Up-Down-Down |
0.959 | - | - | - | - | - | 0.959 | Mlig455_058929 {REF} {Length: 4972} {Pfam: Mab-21 protein [PF03281.16, score=38.7]} {RNA1509_47729, RNA1509_51832} {RNA1310_6164, RNA1509_47729} {RNA1509_47729, RNA815_1489.1} | |
21. | MligTC455_14655 | 504 | 10.51 | Mlig455_032155, Mlig455_032161 | Neo: - Age: Down-Down-Up |
0.957 | - | - | - | - | - | 0.957 | Mlig455_032155 {REF} {Length: 977} {Pfam: Ectodermal ciliogenesis protein [PF15795.7, score=76.8]} {RNA1310_42665.1} {RNA815_17724} Mlig455_032161 {REF} {Length: 351} {NoTransDecoderORF} {RNA1310_42665.2} {RNA815_17724} |
|
22. | MligTC455_20138 | 552 | 11.5 | Mlig455_025065 | Neo: - Age: - |
C10orf67 | 0.951 | - | - | - | - | - | 0.951 | Mlig455_025065 {REF} {Length: 2730} {Human: ENSG00000179133, C10orf67, chromosome 10 open reading frame 67, [Score=62.0, Expect=1e-09]} {Mouse: ENSMUSG00000026734, 4921504E06Rik, RIKEN cDNA 4921504E06 gene, [RH, Score=58.9, Expect=6e-09]} {RNA1509_39095} {RNA1310_11849} {RNA815_12876} |
23. | MligTC455_20139 | 549 | 11.45 | Mlig455_025080 | Neo: - Age: logFC(26M/2M)=-0.355 |
C10orf67 | 0.95 | - | - | - | - | - | 0.950 | Mlig455_025080 {REF} {Length: 2190} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4709) [PF15821.7, score=70.4]} {Human: ENSG00000179133, C10orf67, chromosome 10 open reading frame 67, [RH, Score=96.7, Expect=2e-20]} {Mouse: ENSMUSG00000026734, 4921504E06Rik, RIKEN cDNA 4921504E06 gene, [RH, Score=59.7, Expect=7e-09]} {RNA1509_11167, RNA1509_39095} {RNA1310_11849, RNA1509_11167, RNA1509_39095} {RNA1509_11167, RNA1509_39095, RNA815_12876} |