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Results for MligTC455_11545

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_11545 575 11.98 Mlig455_028030

Neo: -

Age: -

 Mlig455_028030 {REF} {Length: 5018} {TRANSSPLICED} {Smed: dd_Smed_v6_12364_0_1, dd_Smed_v6_12364_0_1, [RH, Score=485, Expect=7e-150]} {RNA1509_11986} {RNA1310_1255.1} {RNA815_6764}

Cumulative graph for MligTC455_11545

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.162 3.854 0.29927 0.94883
RegionR2 -0.303 3.854 0.48507 0.86819
RegionR3 -0.77 3.854 0.04423 0.36738
RegionR4 0.504 3.854 0.29027 0.60088
RegionR5 -0.45 3.854 0.20885 0.50407
RegionR6 -0.722 3.854 0.06829 0.48770
RegionR7 0.26 3.854 0.58581 1.00000
RegionR8 0.32 3.854 0.60518 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.952 3.854 0.03341 0.64253
RegenerationR2 0.276 3.854 0.41755 0.82574
RegenerationR3 0.204 3.854 0.63377 0.92200
RegenerationR4 -0.494 3.854 0.26024 0.70831
RegenerationR5 0.033 3.854 0.93357 1.00000
RegenerationR6 -0.489 3.854 0.29787 0.64833
RegenerationBL -0.263 3.854 0.60673 0.95302
RegenerationTP -0.359 3.854 0.50312 0.90248


Genes with expression patterns similar to MligTC455_11545

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_11545 575 11.98 Mlig455_028030

Neo: -

Age: -

 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_028030 {REF} {Length: 5018} {TRANSSPLICED} {Smed: dd_Smed_v6_12364_0_1, dd_Smed_v6_12364_0_1, [RH, Score=485, Expect=7e-150]} {RNA1509_11986} {RNA1310_1255.1} {RNA815_6764}
2. MligTC455_41536 1373 28.6 Mlig455_025144, Mlig455_063906

Neo: -

Age: -

 ARHGAP18 3.495 0.784 - - 0.845 0.906 0.960

Mlig455_025144 {REF} {Length: 2359} {TRANSSPLICED} {Pfam: RhoGAP domain [PF00620.29, score=119.3]} {Human: ENSG00000146376, ARHGAP18, Rho GTPase activating protein 18, [Score=135, Expect=4e-34]} {Mouse: ENSMUSG00000039031, Arhgap18, Rho GTPase activating protein 18, [Score=137, Expect=5e-35]} {Dmel: FBgn0259216, RhoGAP102A, Rho GTPase activating protein at 102A, [RH, Score=74.3, Expect=5e-14]} {Celegans: WBGene00015303, rga-6, Rho GTPase Activating protein, [RH, Score=89.4, Expect=6e-19]} {Smed: dd_Smed_v6_4507_0_1, dd_Smed_v6_4507_0_1, [Score=79.3, Expect=7e-16]} {RNA1509_33491} {RNA1310_7194.1} {RNA815_2432}

Mlig455_063906 {REF} {Length: 2571} {TRANSSPLICED} {Pfam: RhoGAP domain [PF00620.29, score=118.8]} {Human: ENSG00000146376, ARHGAP18, Rho GTPase activating protein 18, [RH, Score=159, Expect=5e-42]} {Mouse: ENSMUSG00000039031, Arhgap18, Rho GTPase activating protein 18, [RH, Score=161, Expect=8e-43]} {Dmel: FBgn0259216, RhoGAP102A, Rho GTPase activating protein at 102A, [RH, Score=74.7, Expect=7e-14]} {Celegans: WBGene00015303, rga-6, Rho GTPase Activating protein, [RH, Score=89.0, Expect=2e-18]} {Smed: dd_Smed_v6_4507_0_2, dd_Smed_v6_4507_0_2, [Score=78.2, Expect=3e-15]} {RNA1509_33491} {RNA1310_7194.1} {RNA815_2432}
3. MligTC455_04273 1905 39.69 Mlig455_014980, Mlig455_027959, Mlig455_027986, Mlig455_042890, Mlig455_056217

Neo: -

Age: logFC(26M/2M)=0.365

Region-enriched R4: 1.233/0.00679

 2.632 0.960 - 0.848 - - 0.824

Mlig455_014980 {REF} {Length: 2410} {TRANSSPLICED} {Pfam: Plasmid protein of unknown function (Plasmid_RAQPRD) [PF09686.12, score=24.0]} {RNA1509_7158} {RNA1310_4079} {RNA815_282.1}

Mlig455_027959 {REF} {Length: 3263} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=33.3]} {RNA1509_33750} {RNA1310_4079} {RNA815_20382}

Mlig455_027986 {REF} {Length: 3151} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=33.3]} {RNA1509_33750} {RNA1310_4079} {RNA815_20382}

Mlig455_042890 {REF} {Length: 2273} {RNA1509_7158} {RNA1310_4079} {RNA815_282.1}

Mlig455_056217 {REF} {Length: 3151} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=33.3]} {RNA1509_33750} {RNA1310_4079} {RNA815_20382}
4. MligTC455_33416 2350 48.96 Mlig455_013289, Mlig455_035934

Neo: -

Age: logFC(26M/2M)=-0.185

 KIF15 2.628 0.926 - - - 0.747 0.955

Mlig455_013289 {REF} {Length: 3175} {TRANSSPLICED} {Pfam: Kinesin motor domain [PF00225.25, score=179.5]; Domain of unknown function (DUF4472) [PF14739.8, score=82.3]; Microtubule binding [PF16796.7, score=46.4]} {Human: ENSG00000163808, KIF15, kinesin family member 15, [Score=137, Expect=2e-32]; ENSG00000280610, KIF15, kinesin family member 15, [Score=137, Expect=2e-32]} {Mouse: ENSMUSG00000036768, Kif15, kinesin family member 15, [Score=134, Expect=2e-31]} {Dmel: FBgn0032243, Klp31E, Kinesin-like protein at 31E, [Score=136, Expect=2e-32]} {Celegans: WBGene00002224, klp-13, Kinesin like protein KLP-13; Kinesin-like protein, [Score=116, Expect=1e-26]} {Smed: dd_Smed_v6_10482_0_1, dd_Smed_v6_10482_0_1, [RH, Score=179, Expect=1e-46]} {RNA1509_9022, RNA1509_9301} {RNA1310_2377, RNA1509_9022, RNA1509_9301} {RNA1509_9022, RNA1509_9301, RNA815_1853}

Mlig455_035934 {REF} {Length: 3174} {TRANSSPLICED} {Pfam: Kinesin motor domain [PF00225.25, score=179.5]; Domain of unknown function (DUF4472) [PF14739.8, score=82.3]; Microtubule binding [PF16796.7, score=46.4]} {Human: ENSG00000163808, KIF15, kinesin family member 15, [Score=137, Expect=2e-32]; ENSG00000280610, KIF15, kinesin family member 15, [Score=137, Expect=2e-32]} {Mouse: ENSMUSG00000036768, Kif15, kinesin family member 15, [Score=134, Expect=2e-31]} {Dmel: FBgn0032243, Klp31E, Kinesin-like protein at 31E, [Score=136, Expect=2e-32]} {Celegans: WBGene00002224, klp-13, Kinesin like protein KLP-13; Kinesin-like protein, [Score=116, Expect=1e-26]} {Smed: dd_Smed_v6_10482_0_1, dd_Smed_v6_10482_0_1, [RH, Score=179, Expect=1e-46]} {RNA1509_9301} {RNA1310_2377} {RNA815_1853}
5. MligTC455_38803 3547 73.9 Mlig455_064495, Mlig455_064514, Mlig455_066056

Neo: -

Age: -

 PFKP 2.577 - - 0.751 0.867 - 0.959

Mlig455_064495 {REF} {Length: 4264} {TRANSSPLICED} {Pfam: Phosphofructokinase [PF00365.22, score=623.4]} {Human: ENSG00000067057, PFKP, phosphofructokinase, platelet, [RH, Score=851, Expect=0.0]; ENSG00000141959, PFKL, phosphofructokinase, liver type, [RH, Score=849, Expect=0.0]; ENSG00000152556, PFKM, phosphofructokinase, muscle, [RH, Score=833, Expect=0.0]} {Mouse: ENSMUSG00000020277, Pfkl, phosphofructokinase, liver, B-type, [RH, Score=852, Expect=0.0]; ENSMUSG00000033065, Pfkm, phosphofructokinase, muscle, [RH, Score=836, Expect=0.0]; ENSMUSG00000021196, Pfkp, phosphofructokinase, platelet, [RH, Score=835, Expect=0.0]} {Dmel: FBgn0003071, Pfk, Phosphofructokinase, [RH, Score=860, Expect=0.0]} {Celegans: WBGene00022199, pfk-1.1, ATP-dependent 6-phosphofructokinase 1, [RH, Score=827, Expect=0.0]} {Smed: dd_Smed_v6_1604_0_1, dd_Smed_v6_1604_0_1, [RH, Score=909, Expect=0.0]} {RNA1509_2362} {RNA1310_6048.2} {RNA815_2567}

Mlig455_064514 {REF} {Length: 4193} {TRANSSPLICED} {Pfam: Phosphofructokinase [PF00365.22, score=623.4]} {Human: ENSG00000067057, PFKP, phosphofructokinase, platelet, [RH, Score=852, Expect=0.0]; ENSG00000141959, PFKL, phosphofructokinase, liver type, [RH, Score=849, Expect=0.0]; ENSG00000152556, PFKM, phosphofructokinase, muscle, [RH, Score=833, Expect=0.0]} {Mouse: ENSMUSG00000020277, Pfkl, phosphofructokinase, liver, B-type, [RH, Score=853, Expect=0.0]; ENSMUSG00000033065, Pfkm, phosphofructokinase, muscle, [RH, Score=837, Expect=0.0]; ENSMUSG00000021196, Pfkp, phosphofructokinase, platelet, [RH, Score=835, Expect=0.0]} {Dmel: FBgn0003071, Pfk, Phosphofructokinase, [RH, Score=860, Expect=0.0]} {Celegans: WBGene00022199, pfk-1.1, ATP-dependent 6-phosphofructokinase 1, [RH, Score=827, Expect=0.0]} {Smed: dd_Smed_v6_1604_0_1, dd_Smed_v6_1604_0_1, [RH, Score=910, Expect=0.0]} {RNA1509_2362} {RNA1310_6048.2} {RNA815_2567}

Mlig455_066056 {REF} {Length: 4089} {TRANSSPLICED} {Pfam: Phosphofructokinase [PF00365.22, score=623.5]} {Human: ENSG00000067057, PFKP, phosphofructokinase, platelet, [RH, Score=852, Expect=0.0]; ENSG00000141959, PFKL, phosphofructokinase, liver type, [RH, Score=849, Expect=0.0]; ENSG00000152556, PFKM, phosphofructokinase, muscle, [RH, Score=833, Expect=0.0]} {Mouse: ENSMUSG00000020277, Pfkl, phosphofructokinase, liver, B-type, [RH, Score=852, Expect=0.0]; ENSMUSG00000033065, Pfkm, phosphofructokinase, muscle, [RH, Score=837, Expect=0.0]; ENSMUSG00000021196, Pfkp, phosphofructokinase, platelet, [RH, Score=834, Expect=0.0]} {Dmel: FBgn0003071, Pfk, Phosphofructokinase, [RH, Score=860, Expect=0.0]} {Celegans: WBGene00022199, pfk-1.1, ATP-dependent 6-phosphofructokinase 1, [RH, Score=827, Expect=0.0]} {Smed: dd_Smed_v6_1604_0_1, dd_Smed_v6_1604_0_1, [RH, Score=910, Expect=0.0]} {RNA1509_2362} {RNA1310_6048.2} {RNA815_2567}
6. MligTC455_31469 1076 22.43 Mlig455_002483

Neo: -

Age: Down-Up-Down

 CCDC189 2.576 - - - 0.725 0.957 0.894 Mlig455_002483 {REF} {Length: 6604} {Pfam: Flagellar C1a complex subunit C1a-32 [PF14769.8, score=83.5]; PDZ domain [PF00595.26, score=76.3]; PDZ domain [PF17820.3, score=70.7]; PDZ domain [PF13180.8, score=43.3]; Tricorn protease PDZ domain [PF14685.8, score=23.4]} {Human: ENSG00000196118, CCDC189, coiled-coil domain containing 189, [Score=100, Expect=2e-22]} {Mouse: ENSMUSG00000057176, Ccdc189, coiled-coil domain containing 189, [Score=107, Expect=9e-25]} {Dmel: FBgn0024728, Slip1, [Score=61.6, Expect=3e-09]} {Celegans: WBGene00016846, C50F7.6, [Score=69.3, Expect=2e-12]} {Smed: dd_Smed_v6_12703_0_1, dd_Smed_v6_12703_0_1, [Score=117, Expect=6e-29]} {RNA1509_34490, RNA1509_53384} {RNA1310_23890, RNA1509_53384} {RNA1509_53384, RNA815_12270.1}
7. MligTC455_40202 595 12.39 Mlig455_057253

Neo: -

Age: logFC(26M/2M)=-0.440

 DCLK3 2.544 - - 0.952 0.835 0.757 - Mlig455_057253 {REF} {Length: 4012} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.9]; Fungal protein kinase [PF17667.3, score=25.3]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=18.9]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=371, Expect=1e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=2e-113]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=370, Expect=1e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=296, Expect=6e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=352, Expect=1e-105]} {RNA1509_13597, RNA1509_49808} {RNA1310_2158.1, RNA1509_13597, RNA1509_49808} {RNA1509_13597, RNA1509_49808, RNA815_2598}
8. MligTC455_40201 607 12.65 Mlig455_052028

Neo: -

Age: logFC(26M/2M)=-0.526

 DCLK3 2.542 - - 0.952 0.828 0.762 - Mlig455_052028 {REF} {Length: 3990} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.8]; Fungal protein kinase [PF17667.3, score=26.5]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=19.0]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=370, Expect=2e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=8e-110]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=369, Expect=3e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=295, Expect=7e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=351, Expect=2e-105]} {RNA1509_13597} {RNA1310_2158.1} {RNA815_2598}
9. MligTC455_37319 757 15.77 Mlig455_065923

Neo: -

Age: logFC(26M/2M)=-0.337

 2.539 0.956 - - 0.807 0.776 - Mlig455_065923 {REF} {Length: 6168} {RNA1509_7080} {RNA1310_599.1} {RNA815_956.1}
10. MligTC455_41197 316 6.58 Mlig455_017826

Neo: -

Age: -

 CAMK4 2.5 - - 0.956 0.732 - 0.812 Mlig455_017826 {REF} {Length: 1398} {Pfam: Protein kinase domain [PF00069.27, score=243.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=104.3]; ABC1 atypical kinase-like domain [PF03109.18, score=19.6]} {Human: ENSG00000152495, CAMK4, calcium/calmodulin dependent protein kinase IV, [Score=358, Expect=6e-121]} {Mouse: ENSMUSG00000038128, Camk4, calcium/calmodulin-dependent protein kinase IV, [Score=363, Expect=5e-123]} {Dmel: FBgn0016126, CaMKI, Calcium/calmodulin-dependent protein kinase I, [Score=256, Expect=2e-82]} {Celegans: WBGene00000553, cmk-1, Calcium/calmodulin-dependent protein kinase type 1, [Score=261, Expect=3e-85]} {Smed: dd_Smed_v6_10731_0_1, dd_Smed_v6_10731_0_1, [Score=363, Expect=5e-125]} {RNA1509_46951} {RNA1310_29212.1, RNA1509_46951} {RNA1509_46951, RNA815_16533}
11. MligTC455_37317 716 14.92 Mlig455_016836

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=-0.348

 2.494 0.953 - - 0.773 0.768 - Mlig455_016836 {REF} {Length: 5169} {RNA1509_5945} {RNA1310_599.1} {RNA815_1437}
12. MligTC455_52199 1032 21.49 Mlig455_031255, Mlig455_031301

Neo: -

Age: Down-Down-Up

 2.473 0.950 - - 0.744 - 0.779

Mlig455_031255 {REF} {Length: 1896} {Pfam: Innexin [PF00876.20, score=210.3]} {Celegans: WBGene00002127, inx-5, Innexin-5, [Score=134, Expect=1e-34]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=139, Expect=1e-36]} {RNA1509_2324} {RNA1310_13247} {RNA815_6165.1}

Mlig455_031301 {REF} {Length: 2187} {Pfam: Innexin [PF00876.20, score=210.3]} {Celegans: WBGene00002127, inx-5, Innexin-5, [Score=134, Expect=1e-34]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=139, Expect=2e-36]} {RNA1509_2324} {RNA1310_13247} {RNA815_6165.1}
13. MligTC455_15349 404 8.41 Mlig455_026642

Neo: -

Age: logFC(26M/2M)=-0.377

 2.456 - - 0.760 0.736 - 0.960 Mlig455_026642 {REF} {Length: 3114} {Pfam: EF-hand domain [PF13405.8, score=70.7]; EF-hand domain pair [PF13499.8, score=54.9]; EF hand [PF00036.34, score=48.7]; EF-hand domain pair [PF13833.8, score=33.4]; EF-hand domain [PF08976.13, score=22.0]} {Dmel: FBgn0038163, CG10841, [RH, Score=209, Expect=1e-56]} {Smed: dd_Smed_v6_8441_0_1, dd_Smed_v6_8441_0_1, [RH, Score=828, Expect=0.0]} {RNA1509_4624} {RNA1310_4455} {RNA815_1290}
14. MligTC455_53544 626 13.04 Mlig455_025841

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.481

 HEYL 1.887 0.932 - - - - 0.955 Mlig455_025841 {REF} {Length: 2716} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=42.7]} {Human: ENSG00000163909, HEYL, hes related family bHLH transcription factor with YRPW motif-like, [Score=57.4, Expect=3e-08]; ENSG00000135547, HEY2, hes related family bHLH transcription factor with YRPW motif 2, [Score=55.1, Expect=1e-07]; ENSG00000187821, HELT, helt bHLH transcription factor, [Score=55.1, Expect=1e-07]} {Mouse: ENSMUSG00000032744, Heyl, hairy/enhancer-of-split related with YRPW motif-like, [Score=56.6, Expect=4e-08]; ENSMUSG00000047171, Helt, helt bHLH transcription factor, [Score=55.1, Expect=7e-08]; ENSMUSG00000019789, Hey2, hairy/enhancer-of-split related with YRPW motif 2, [Score=54.7, Expect=2e-07]} {Dmel: FBgn0259938, cwo, clockwork orange, [Score=63.5, Expect=4e-10]} {Celegans: WBGene00015646, mlt-10, [RH, Score=176, Expect=2e-46]} {Smed: dd_Smed_v6_22479_0_1, dd_Smed_v6_22479_0_1, [Score=51.2, Expect=9e-07]} {RNA1509_49122} {RNA1310_18992.1} {RNA815_16883}
15. MligTC455_27892 1176 24.51 Mlig455_059337

Neo: -

Age: logFC(26M/2M)=-0.371

Regeneration-upregulated BL: 1.618

Regeneration-enriched BL: 1.618

 1.87 0.919 - - - - 0.951 Mlig455_059337 {REF} {Length: 1631} {RNA1509_9554} {RNA1310_29242} {RNA815_13125}
16. MligTC455_21143 296 6.18 Mlig455_016004

Neo: -

Age: logFC(26M/2M)=-0.497

Regeneration-downregulated R6: -2.391

Regeneration-depleted R6: -2.391

 WNT5A 1.868 0.892 - - - - 0.976 Mlig455_016004 {REF} {Length: 3460} {Pfam: wnt family [PF00110.21, score=323.9]} {Human: ENSG00000114251, WNT5A, Wnt family member 5A, [RH, Score=282, Expect=7e-92]; ENSG00000111186, WNT5B, Wnt family member 5B, [RH, Score=280, Expect=4e-91]} {Mouse: ENSMUSG00000021994, Wnt5a, wingless-type MMTV integration site family, member 5A, [RH, Score=283, Expect=1e-92]; ENSMUSG00000030170, Wnt5b, wingless-type MMTV integration site family, member 5B, [RH, Score=277, Expect=4e-90]} {Dmel: FBgn0004360, Wnt2, Wnt oncogene analog 2, [RH, Score=201, Expect=7e-61]} {Celegans: WBGene00000858, cwn-2, [RH, Score=249, Expect=9e-80]} {Smed: dd_Smed_v6_15469_0_1, dd_Smed_v6_15469_0_1, [RH, Score=283, Expect=1e-92]} {RNA1509_15617, RNA1509_43347} {RNA1310_6635.1, RNA1509_15617, RNA1509_43347} {RNA1509_15617, RNA1509_43347, RNA815_13704}
17. MligTC455_24026 610 12.71 Mlig455_006439

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.479

 DMBT1 1.815 - - - - 0.855 0.960 Mlig455_006439 {REF} {Length: 2543} {Pfam: Zona pellucida-like domain [PF00100.25, score=88.4]; Scavenger receptor cysteine-rich domain [PF00530.20, score=66.6]} {Human: ENSG00000187908, DMBT1, deleted in malignant brain tumors 1, [Score=62.0, Expect=3e-09]} {Smed: dd_Smed_v6_8185_0_1, dd_Smed_v6_8185_0_1, [RH, Score=78.6, Expect=3e-15]} {RNA1509_6352} {RNA1310_8273} {RNA815_2734}
18. MligTC455_45672 743 15.49 Mlig455_034867

Neo: -

Age: -

Region-enriched R4: 1.237/0.02291

 TMEM80 1.788 - - - 0.827 - 0.961 Mlig455_034867 {REF} {Length: 1153} {TRANSSPLICED} {Pfam: Predicted membrane protein [PF09799.11, score=79.4]} {Human: ENSG00000177042, TMEM80, transmembrane protein 80, [RH, Score=53.9, Expect=1e-08]} {Celegans: WBGene00194710, mks-2, MecKel-Gruber Syndrome (MKS) homolog, [RH, Score=49.7, Expect=6e-08]} {Smed: dd_Smed_v6_14636_0_1, dd_Smed_v6_14636_0_1, [Score=73.6, Expect=5e-17]} {RNA1509_35137, RNA1509_36429, RNA1509_39419} {RNA1310_30722.1, RNA1509_36429, RNA1509_39419} {RNA1509_36429, RNA1509_39419, RNA815_13266}
19. MligTC455_14655 504 10.51 Mlig455_032155, Mlig455_032161

Neo: -

Age: Down-Down-Up

 1.776 - - - 0.824 - 0.952

Mlig455_032155 {REF} {Length: 977} {Pfam: Ectodermal ciliogenesis protein [PF15795.7, score=76.8]} {RNA1310_42665.1} {RNA815_17724}

Mlig455_032161 {REF} {Length: 351} {NoTransDecoderORF} {RNA1310_42665.2} {RNA815_17724}
20. MligTC455_15267 527 10.97 Mlig455_038934

Neo: -

Age: -

 1.768 0.800 - - - - 0.968 Mlig455_038934 {REF} {Length: 4442} {TRANSSPLICED} {Pfam: ALMS motif [PF15309.8, score=45.3]} {Smed: dd_Smed_v6_5064_0_1, dd_Smed_v6_5064_0_1, [Score=85.9, Expect=6e-17]} {RNA1509_20372, RNA1509_29169, RNA1509_51896, RNA1509_52383} {RNA1310_3943.1, RNA1509_20372, RNA1509_29169, RNA1509_51896, RNA1509_52383} {RNA1509_20372, RNA1509_29169, RNA1509_51896, RNA1509_52383, RNA815_11083}
21. MligTC455_11607 191 3.98 Mlig455_001162

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.741

 1.757 0.954 - - 0.803 - - Mlig455_001162 {REF} {Length: 844} {TRANSSPLICED} {RNA1509_27526} {RNA1310_21583} {RNA815_12355}
22. MligTC455_22897 1057 22.03 Mlig455_064864

Neo: -

Age: Up-Down-Down

 LCA5 1.737 - - - 0.782 - 0.955 Mlig455_064864 {REF} {Length: 4344} {TRANSSPLICED} {Pfam: Ciliary protein causing Leber congenital amaurosis disease [PF15619.8, score=143.2]} {Human: ENSG00000135338, LCA5, LCA5, lebercilin, [RH, Score=107, Expect=2e-23]} {Mouse: ENSMUSG00000032258, Lca5, Leber congenital amaurosis 5 (human), [RH, Score=104, Expect=1e-22]} {Dmel: FBgn0036687, CG6652, [RH, Score=53.1, Expect=8e-07]} {Smed: dd_Smed_v6_14572_0_1, dd_Smed_v6_14572_0_1, [RH, Score=101, Expect=5e-22]} {RNA1509_3039} {RNA1310_7273} {RNA815_3712}
23. MligTC455_43906 878 18.29 Mlig455_044333, Mlig455_044345

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.277

 RAI14 1.732 - - - - 0.774 0.958

Mlig455_044333 {REF} {Length: 5825} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=81.1]; Ankyrin repeat [PF00023.32, score=72.8]; Ankyrin repeats (many copies) [PF13637.8, score=63.6]; Ankyrin repeat [PF13606.8, score=48.5]; Ankyrin repeats (many copies) [PF13857.8, score=44.2]} {Human: ENSG00000039560, RAI14, retinoic acid induced 14, [Score=90.1, Expect=3e-17]} {Mouse: ENSMUSG00000022246, Rai14, retinoic acid induced 14, [Score=94.4, Expect=9e-19]; ENSMUSG00000007827, Ankrd26, ankyrin repeat domain 26, [Score=89.7, Expect=3e-17]} {Dmel: FBgn0039590, CG10011, [Score=82.4, Expect=4e-15]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=85.9, Expect=3e-16]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [Score=73.9, Expect=7e-13]} {RNA1509_7603} {RNA1310_960.3} {RNA815_5173}

Mlig455_044345 {REF} {Length: 6035} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=87.7]; Ankyrin repeat [PF00023.32, score=72.9]; Ankyrin repeats (many copies) [PF13637.8, score=66.8]; Ankyrin repeats (many copies) [PF13857.8, score=50.5]; Ankyrin repeat [PF13606.8, score=50.0]} {Human: ENSG00000039560, RAI14, retinoic acid induced 14, [Score=94.7, Expect=9e-19]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=92.0, Expect=6e-19]} {Mouse: ENSMUSG00000022246, Rai14, retinoic acid induced 14, [Score=99.4, Expect=3e-20]} {Dmel: FBgn0039590, CG10011, [Score=87.4, Expect=1e-16]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=86.3, Expect=2e-16]} {Smed: dd_Smed_v6_7952_0_2, dd_Smed_v6_7952_0_2, [Score=80.5, Expect=8e-15]} {RNA1509_7603} {RNA1310_960.3} {RNA815_5173}
24. MligTC455_51933 583 12.15 Mlig455_024511

Neo: -

Age: logFC(26M/2M)=-0.429

Region-enriched R2: 2.089/0.00081

 CBSL 1.723 0.961 - - - 0.762 - Mlig455_024511 {REF} {Length: 1959} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=138.0]; CBS domain [PF00571.30, score=48.9]} {Human: ENSG00000274276, CBSL, cystathionine-beta-synthase like, [Score=463, Expect=3e-160]; ENSG00000160200, CBS, cystathionine-beta-synthase, [Score=463, Expect=3e-160]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [Score=467, Expect=6e-162]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [Score=327, Expect=2e-107]} {Celegans: WBGene00013866, cbs-1, Cystathionine Beta-Synthase, [Score=264, Expect=2e-81]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [Score=511, Expect=6e-180]} {RNA1509_36721} {RNA1310_10809} {RNA815_3797.1}
25. MligTC455_24891 845 17.6 Mlig455_016464

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.290

 1.703 0.958 - - - 0.745 - Mlig455_016464 {REF} {Length: 2447} {RNA1509_20271, RNA1509_46463} {RNA1310_10597.1, RNA1509_20271, RNA1509_46463} {RNA1509_20271, RNA1509_46463, RNA815_3690.1}
26. MligTC455_39651 1287 26.82 Mlig455_005542

Neo: -

Age: Up-Down-Up

Regeneration-downregulated BL: -1.833

Regeneration-depleted BL: -1.833

 RNF217 1.702 0.951 - 0.751 - - - Mlig455_005542 {REF} {Length: 2597} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=51.0]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=166, Expect=4e-45]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=163, Expect=3e-44]} {Dmel: FBgn0025186, ari-2, ariadne 2, [Score=68.9, Expect=3e-12]} {Celegans: WBGene00016156, C27A12.6, [Score=72.4, Expect=2e-13]} {Smed: dd_Smed_v6_7110_0_1, dd_Smed_v6_7110_0_1, [Score=128, Expect=7e-32]} {RNA1509_57487} {RNA1310_11553.2} {RNA815_5548}
27. MligTC455_43962 120 2.5 Mlig455_020783

Neo: -

Age: -

 TRAF5 1.702 - - 0.953 - - 0.749 Mlig455_020783 {REF} {Length: 3242} {Human: ENSG00000082512, TRAF5, TNF receptor associated factor 5, [Score=90.5, Expect=3e-20]} {Mouse: ENSMUSG00000026637, Traf5, TNF receptor-associated factor 5, [Score=88.6, Expect=1e-20]; ENSMUSG00000111385, Traf5, TNF receptor-associated factor 5, [Score=88.6, Expect=1e-20]} {Dmel: FBgn0026319, Traf4, TNF-receptor-associated factor 4, [Score=70.9, Expect=6e-14]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [Score=99.0, Expect=8e-24]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [Score=132, Expect=8e-36]} {RNA1310_36792.1} {RNA815_40908}
28. MligTC455_11609 284 5.92 Mlig455_070575

Neo: -

Age: -

 1.698 0.953 - - 0.745 - - Mlig455_070575 {REF} {Length: 3293} {TRANSSPLICED} {Pfam: Cysteine and tyrosine-rich protein 1 [PF10873.10, score=23.2]} {RNA1509_18810, RNA1509_40814} {RNA1310_7682.1, RNA1509_18810, RNA1509_40814} {RNA1509_18810, RNA1509_40814, RNA815_11219}
29. MligTC455_11608 280 5.84 Mlig455_001322

Neo: -

Age: -

 1.694 0.951 - - 0.743 - - Mlig455_001322 {REF} {Length: 652} {Pfam: RRM-like domain [PF11835.10, score=21.4]} {RNA1509_36309} {RNA1310_7682.1} {RNA815_30014}
30. MligTC455_19996 1327 27.64 Mlig455_040679, Mlig455_064542

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.357

Region-enriched R4: 1.353/0.00087

 1.694 0.957 - - - 0.737 -

Mlig455_040679 {REF} {Length: 1076} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=33.8]} {RNA1509_18707} {RNA1310_25620, RNA1509_18707} {RNA1509_18707, RNA815_17844}

Mlig455_064542 {REF} {Length: 1060} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=33.5]} {RNA1509_18707} {RNA1310_25620} {RNA815_17844}
31. MligTC455_29201 1280 26.67 Mlig455_049817

Neo: -

Age: -

Regeneration-downregulated BL: -1.729

Regeneration-depleted BL: -1.729

 OTOF 1.691 - - - 0.739 - 0.952 Mlig455_049817 {REF} {Length: 7973} {Pfam: C2 domain [PF00168.32, score=225.3]; FerB (NUC096) domain [PF08150.14, score=99.1]; Ferlin C-terminus [PF16165.7, score=97.7]; FerI (NUC094) domain [PF08151.14, score=61.5]} {Human: ENSG00000115155, OTOF, otoferlin, [RH, Score=910, Expect=0.0]} {Mouse: ENSMUSG00000062372, Otof, otoferlin, [RH, Score=915, Expect=0.0]} {Dmel: FBgn0266757, mfr, misfire, [RH, Score=301, Expect=4e-84]} {Celegans: WBGene00001414, fer-1, Sperm vesicle fusion protein fer-1, [Score=150, Expect=9e-36]} {Smed: dd_Smed_v6_5915_0_1, dd_Smed_v6_5915_0_1, [Score=1476, Expect=0.0]} {RNA1509_5256} {RNA1310_1416.2} {RNA815_411.1}
32. MligTC455_44366 1536 32 Mlig455_002673

Neo: -

Age: logFC(26M/2M)=-0.411

 MYCBPAP 1.683 - - - - 0.722 0.961 Mlig455_002673 {REF} {Length: 3090} {Pfam: MYCBP-associated protein family [PF14646.8, score=366.5]} {Human: ENSG00000136449, MYCBPAP, MYCBP associated protein, [RH, Score=280, Expect=3e-80]} {Mouse: ENSMUSG00000039110, Mycbpap, MYCBP associated protein, [RH, Score=270, Expect=4e-77]} {Smed: dd_Smed_v6_11993_0_1, dd_Smed_v6_11993_0_1, [RH, Score=326, Expect=4e-98]} {RNA1509_4206} {RNA1310_3498.3} {RNA815_1306}
33. MligTC455_37422 424 8.84 Mlig455_046336, Mlig455_068232

Neo: -

Age: -

 1.675 0.966 - - - - 0.709

Mlig455_046336 {REF} {Length: 2188} {RNA1509_23270, RNA1509_23548} {RNA1310_21891, RNA1509_23270, RNA1509_23548} {RNA1509_23270, RNA1509_23548, RNA815_2813.1}

Mlig455_068232 {REF} {Length: 2388} {RNA1509_23548} {RNA1310_21891} {RNA815_2813.1}
34. MligTC455_44365 1412 29.41 Mlig455_002492

Neo: -

Age: logFC(26M/2M)=0.553

 MYCBPAP 1.675 - - - - 0.707 0.968 Mlig455_002492 {REF} {Length: 3081} {Pfam: MYCBP-associated protein family [PF14646.8, score=368.3]} {Human: ENSG00000136449, MYCBPAP, MYCBP associated protein, [RH, Score=280, Expect=2e-80]} {Mouse: ENSMUSG00000039110, Mycbpap, MYCBP associated protein, [RH, Score=276, Expect=5e-79]} {Smed: dd_Smed_v6_11993_0_1, dd_Smed_v6_11993_0_1, [RH, Score=323, Expect=3e-97]} {RNA1509_4206} {RNA1310_3498.3} {RNA815_1306}
35. MligTC455_30440 418 8.71 Mlig455_064738

Neo: -

Age: logFC(26M/2M)=-0.725

 1.661 - - 0.951 0.710 - - Mlig455_064738 {REF} {Length: 1764} {RNA1509_50227} {RNA1310_7897.2} {RNA815_2064.1}
36. MligTC455_24468 393 8.19 Mlig455_022743

Neo: -

Age: -

 0.976 0.976 - - - - - Mlig455_022743 {REF} {Length: 3079} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=97.7]} {Dmel: FBgn0033028, CG11665, [Score=53.1, Expect=4e-07]} {Celegans: WBGene00013353, Y59A8B.21, [RH, Score=202, Expect=2e-59]} {Smed: dd_Smed_v6_3455_0_1, dd_Smed_v6_3455_0_1, [RH, Score=377, Expect=4e-127]} {RNA1509_55196} {RNA1310_9041, RNA1509_55196} {RNA1509_55196, RNA815_9031}
37. MligTC455_30738 222 4.62 Mlig455_056793

Neo: -

Age: -

 0.974 0.974 - - - - - Mlig455_056793 {REF} {Length: 936} {NoTransDecoderORF} {RNA1509_50997} {RNA1310_6937.2} {RNA815_61058}
38. MligTC455_27606 737 15.35 Mlig455_021387

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.410

Region-enriched R2: 2.253/0.00085

 DNAH2 0.97 - - - - - 0.970 Mlig455_021387 {REF} {Length: 14312} {TRANSSPLICED} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=496.3]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=494.1]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=430.7]; P-loop containing dynein motor region D4 [PF12780.9, score=351.0]; Dynein heavy chain C-terminal domain [PF18199.3, score=339.4]; ATP-binding dynein motor region [PF12781.9, score=291.7]; P-loop containing dynein motor region [PF12775.9, score=252.9]; Microtubule-binding stalk of dynein motor [PF12777.9, score=192.7]; Dynein heavy chain AAA lid domain [PF18198.3, score=179.6]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=162.6]; Dynein heavy chain AAA lid domain [PF17852.3, score=97.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=96.3]; AAA+ lid domain [PF17857.3, score=76.8]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=42.2]; AAA domain [PF13401.8, score=29.8]; AAA domain [PF13238.8, score=26.3]} {Human: ENSG00000183914, DNAH2, dynein axonemal heavy chain 2, [RH, Score=5278, Expect=0.0]} {Mouse: ENSMUSG00000005237, Dnah2, dynein, axonemal, heavy chain 2, [RH, Score=5325, Expect=0.0]} {Dmel: FBgn0001313, kl-2, male fertility factor kl2, [RH, Score=4028, Expect=0.0]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=1132, Expect=0.0]} {Smed: dd_Smed_v6_6941_0_2, dd_Smed_v6_6941_0_2, [RH, Score=5163, Expect=0.0]} {RNA1509_24980, RNA1509_251} {RNA1310_43.1, RNA1509_24980, RNA1509_251} {RNA1509_24980, RNA1509_251, RNA815_22.1}
39. MligTC455_30739 246 5.13 Mlig455_056815

Neo: -

Age: Up-Down-Down

 SLC9A9 0.967 0.967 - - - - - Mlig455_056815 {REF} {Length: 2629} {Pfam: Sodium/hydrogen exchanger family [PF00999.23, score=37.5]} {Human: ENSG00000181804, SLC9A9, solute carrier family 9 member A9, [Score=95.9, Expect=2e-23]} {Mouse: ENSMUSG00000031129, Slc9a9, solute carrier family 9 (sodium/hydrogen exchanger), member 9, [Score=95.5, Expect=2e-23]} {Dmel: FBgn0028703, Nhe3, Na[+]/H[+] hydrogen exchanger 3, [Score=92.0, Expect=3e-22]} {Celegans: WBGene00003733, nhx-5, Sodium/hydrogen exchanger, [Score=77.0, Expect=3e-17]} {Smed: dd_Smed_v6_5461_0_1, dd_Smed_v6_5461_0_1, [Score=100, Expect=2e-25]} {RNA1509_50997} {RNA1310_6937.1} {RNA815_21083}
40. MligTC455_51482 1212 25.25 Mlig455_044675, Mlig455_061488

Neo: -

Age: -

Region-enriched R4: 1.150/0.03018

 CEP41 0.965 - - - - - 0.965

Mlig455_044675 {REF} {Length: 2695} {Pfam: Receptor family ligand binding region [PF01094.30, score=48.6]} {Human: ENSG00000106477, CEP41, centrosomal protein 41, [Score=89.0, Expect=1e-20]} {Mouse: ENSMUSG00000029790, Cep41, centrosomal protein 41, [Score=87.0, Expect=4e-19]} {Smed: dd_Smed_v6_9621_0_1, dd_Smed_v6_9621_0_1, [Score=108, Expect=1e-26]} {RNA1509_29029, RNA1509_35704, RNA1509_58814} {RNA1310_25102.2, RNA1509_29029, RNA1509_58814} {RNA1509_29029, RNA1509_58814, RNA815_9742}

Mlig455_061488 {REF} {Length: 2151} {Pfam: Rhodanese-like domain [PF00581.22, score=38.5]} {Human: ENSG00000106477, CEP41, centrosomal protein 41, [RH, Score=226, Expect=1e-70]} {Mouse: ENSMUSG00000029790, Cep41, centrosomal protein 41, [RH, Score=225, Expect=2e-70]} {Smed: dd_Smed_v6_9621_0_1, dd_Smed_v6_9621_0_1, [RH, Score=286, Expect=9e-95]} {RNA1509_35704} {RNA1310_25102.2} {RNA815_9742}
41. MligTC455_20617 496 10.34 Mlig455_042815

Neo: -

Age: -

Region-enriched R4: 2.359/0.00937

 0.963 - - - - - 0.963 Mlig455_042815 {REF} {Length: 2561} {Smed: dd_Smed_v6_17729_0_1, dd_Smed_v6_17729_0_1, [RH, Score=58.9, Expect=2e-09]} {RNA1509_51521} {RNA1310_20020} {RNA815_8964}
42. MligTC455_40579 537 11.2 Mlig455_003404

Neo: -

Age: -

 0.963 0.963 - - - - - Mlig455_003404 {REF} {Length: 4497} {RNA1509_13496, RNA1509_35589} {RNA1310_2557, RNA1509_13496, RNA1509_35589} {RNA1509_13496, RNA1509_35589, RNA815_4433}
43. MligTC455_29200 404 8.42 Mlig455_016456

Neo: -

Age: -

 OTOF 0.961 - - - - - 0.961 Mlig455_016456 {REF} {Length: 7086} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=232.5]; Ferlin C-terminus [PF16165.7, score=97.7]; FerB (NUC096) domain [PF08150.14, score=96.8]; FerI (NUC094) domain [PF08151.14, score=61.5]} {Human: ENSG00000115155, OTOF, otoferlin, [RH, Score=921, Expect=0.0]} {Mouse: ENSMUSG00000062372, Otof, otoferlin, [RH, Score=925, Expect=0.0]} {Dmel: FBgn0266757, mfr, misfire, [Score=308, Expect=5e-90]} {Celegans: WBGene00001414, fer-1, Sperm vesicle fusion protein fer-1, [Score=151, Expect=5e-36]} {Smed: dd_Smed_v6_5915_0_1, dd_Smed_v6_5915_0_1, [Score=1470, Expect=0.0]} {RNA1509_51560} {RNA1310_1416.6} {RNA815_411.1}
44. MligTC455_30551 1025 21.35 Mlig455_023090, Mlig455_027761, Mlig455_039963

Neo: -

Age: -

 MAP3K19, MAP3K4, TNKS2 0.961 0.961 - - - - -

Mlig455_023090 {REF} {Length: 1558} {Pfam: Protein kinase domain [PF00069.27, score=168.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=125.5]; Fungal protein kinase [PF17667.3, score=29.9]; Phosphotransferase enzyme family [PF01636.25, score=23.8]; ABC1 atypical kinase-like domain [PF03109.18, score=20.6]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=134, Expect=3e-34]} {Mouse: ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=129, Expect=7e-33]; ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=125, Expect=2e-31]} {Dmel: FBgn0024329, Mekk1, [Score=129, Expect=7e-33]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_5198_0_1, dd_Smed_v6_5198_0_1, [Score=108, Expect=3e-26]} {RNA1509_25366, RNA1509_28291, RNA1509_39879} {RNA1310_39116, RNA1509_25366, RNA1509_39879} {RNA1509_25366, RNA1509_39879, RNA815_9030.1}

Mlig455_027761 {REF} {Length: 3012} {Pfam: Protein kinase domain [PF00069.27, score=167.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=125.0]; Ankyrin repeats (3 copies) [PF12796.9, score=85.2]; Ankyrin repeats (many copies) [PF13637.8, score=60.2]; Ankyrin repeat [PF00023.32, score=56.0]; Ankyrin repeat [PF13606.8, score=54.2]; Ankyrin repeats (many copies) [PF13857.8, score=53.2]; Fungal protein kinase [PF17667.3, score=27.7]; ABC1 atypical kinase-like domain [PF03109.18, score=23.8]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=132, Expect=3e-32]; ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=130, Expect=2e-30]; ENSG00000142733, MAP3K6, mitogen-activated protein kinase kinase kinase 6, [Score=127, Expect=1e-29]} {Mouse: ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=130, Expect=9e-31]; ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=125, Expect=6e-29]} {Dmel: FBgn0024329, Mekk1, [Score=128, Expect=4e-30]} {Celegans: WBGene00006443, pak-2, Serine/threonine-protein kinase pak-2, [Score=105, Expect=8e-24]} {Smed: dd_Smed_v6_4849_0_1, dd_Smed_v6_4849_0_1, [Score=109, Expect=1e-24]} {RNA1509_27731} {RNA1310_10050} {RNA815_9030.1}

Mlig455_039963 {REF} {Length: 912} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=78.3]; Ankyrin repeat [PF13606.8, score=60.2]; Ankyrin repeats (many copies) [PF13637.8, score=56.1]; Ankyrin repeats (many copies) [PF13857.8, score=50.9]; Ankyrin repeat [PF00023.32, score=46.6]; Protein kinase domain [PF00069.27, score=37.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=30.6]} {Human: ENSG00000107854, TNKS2, tankyrase 2, [Score=68.2, Expect=2e-11]} {Mouse: ENSMUSG00000024811, Tnks2, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, [Score=66.2, Expect=6e-11]} {Dmel: FBgn0027508, Tnks, tankyrase, [Score=52.4, Expect=9e-07]} {Celegans: WBGene00006941, wnk-1, Serine/threonine-protein kinase WNK, [Score=49.3, Expect=7e-06]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [Score=57.0, Expect=2e-08]} {RNA1509_39395} {RNA1310_28166} {RNA815_10088.2}
45. MligTC455_17761 306 6.38 Mlig455_016874

Neo: -

Age: -

 GDF6 0.96 0.960 - - - - - Mlig455_016874 {REF} {Length: 2735} {Pfam: Transforming growth factor beta like domain [PF00019.22, score=93.2]} {Human: ENSG00000156466, GDF6, growth differentiation factor 6, [RH, Score=120, Expect=2e-29]; ENSG00000143869, GDF7, growth differentiation factor 7, [RH, Score=118, Expect=8e-29]; ENSG00000125965, GDF5, growth differentiation factor 5, [RH, Score=118, Expect=8e-29]} {Mouse: ENSMUSG00000051279, Gdf6, growth differentiation factor 6, [RH, Score=121, Expect=4e-30]; ENSMUSG00000038259, Gdf5, growth differentiation factor 5, [RH, Score=117, Expect=1e-28]} {Dmel: FBgn0000490, dpp, decapentaplegic, [Score=127, Expect=7e-32]} {Celegans: WBGene00000936, dbl-1, DPP/BMP-Like; Decapentaplegic protein homolog, [RH, Score=125, Expect=1e-32]} {Smed: dd_Smed_v6_17402_0_1, dd_Smed_v6_17402_0_1, [RH, Score=124, Expect=8e-32]} {RNA1509_28282} {RNA1310_6507.2} {RNA815_6556}
46. MligTC455_27509 515 10.73 Mlig455_023080

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.476

 0.96 0.960 - - - - - Mlig455_023080 {REF} {Length: 2939} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=39.0]; Ankyrin repeats (many copies) [PF13637.8, score=31.8]; Ankyrin repeat [PF00023.32, score=30.0]; Ankyrin repeat [PF13606.8, score=29.3]; Ankyrin repeats (many copies) [PF13857.8, score=24.6]} {Smed: dd_Smed_v6_16174_0_1, dd_Smed_v6_16174_0_1, [Score=48.5, Expect=2e-06]} {RNA1509_26758} {RNA1310_10050} {RNA815_9030.1}
47. MligTC455_15942 908 18.92 Mlig455_035020, Mlig455_053446

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.273

 NR1I2 0.958 0.958 - - - - -

Mlig455_035020 {REF} {Length: 4424} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.8]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=87.4, Expect=1e-17]} {Mouse: ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=84.3, Expect=6e-17]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=81.3, Expect=6e-16]} {Dmel: FBgn0003720, tll, tailless, [Score=82.0, Expect=3e-16]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=99.4, Expect=2e-21]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=91.3, Expect=3e-19]} {RNA1509_8358} {RNA1310_9876} {RNA815_22592}

Mlig455_053446 {REF} {Length: 4372} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.7]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=87.0, Expect=2e-17]} {Mouse: ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=84.0, Expect=9e-17]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=80.9, Expect=8e-16]; ENSMUSG00000002393, Nr2f6, nuclear receptor subfamily 2, group F, member 6, [Score=80.1, Expect=1e-15]} {Dmel: FBgn0003720, tll, tailless, [Score=82.4, Expect=3e-16]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=99.8, Expect=1e-21]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=91.3, Expect=2e-19]} {RNA1509_8358} {RNA1310_9876} {RNA815_22592}
48. MligTC455_37160 1139 23.73 Mlig455_015317, Mlig455_032998, Mlig455_068744

Neo: -

Age: logFC(26M/2M)=-0.355

Region-enriched R2: 1.560/0.01222

 TTC28 0.958 0.958 - - - - -

Mlig455_015317 {REF} {Length: 5958} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=63.4]; Tetratricopeptide repeat [PF07719.19, score=51.3]; Tetratricopeptide repeat [PF00515.30, score=40.4]; Tetratricopeptide repeat [PF13181.8, score=39.5]; CHAT domain [PF12770.9, score=37.9]; Tetratricopeptide repeat [PF14559.8, score=23.5]; Tetratricopeptide repeat [PF13431.8, score=22.4]; Tetratricopeptide repeat [PF13176.8, score=20.4]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=69.3, Expect=7e-11]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=70.9, Expect=2e-11]} {RNA1509_5411} {RNA1310_761.1} {RNA815_600}

Mlig455_032998 {REF} {Length: 5728} {Pfam: CHAT domain [PF12770.9, score=39.2]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=67.8, Expect=1e-10]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=69.3, Expect=3e-11]} {RNA1509_5411} {RNA1310_761.1} {RNA815_600}

Mlig455_068744 {REF} {Length: 5980} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=62.6]; Tetratricopeptide repeat [PF07719.19, score=49.0]; Tetratricopeptide repeat [PF13181.8, score=39.3]; Tetratricopeptide repeat [PF00515.30, score=38.4]; CHAT domain [PF12770.9, score=37.8]; Tetratricopeptide repeat [PF14559.8, score=22.1]; Tetratricopeptide repeat [PF13431.8, score=20.8]; Tetratricopeptide repeat [PF13176.8, score=19.2]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=66.2, Expect=6e-10]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=67.8, Expect=1e-10]} {RNA1509_5411} {RNA1310_761.2} {RNA815_600}
49. MligTC455_44935 165 3.43 Mlig455_055881

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.487

 IFT81 0.958 - - - - - 0.958 Mlig455_055881 {REF} {Length: 2856} {TRANSSPLICED} {Pfam: Intraflagellar transport 81 calponin homology domain [PF18383.3, score=163.9]; Crescentin protein [PF19220.2, score=18.5]} {Human: ENSG00000122970, IFT81, intraflagellar transport 81, [RH, Score=630, Expect=0.0]} {Mouse: ENSMUSG00000029469, Ift81, intraflagellar transport 81, [RH, Score=644, Expect=0.0]} {Celegans: WBGene00017973, ift-81, IFT (Chlamydomonas IntraFlagellar Transport) homolog, [RH, Score=241, Expect=2e-70]} {Smed: dd_Smed_v6_8803_0_1, dd_Smed_v6_8803_0_1, [RH, Score=620, Expect=0.0]} {RNA1509_5623} {RNA1310_8965} {RNA815_2949}
50. MligTC455_16743 4336 90.32 Mlig455_014160, Mlig455_014169

Neo: -

Age: logFC(26M/2M)=-0.380

 C2orf50 0.957 - - - - - 0.957

Mlig455_014160 {REF} {Length: 868} {Pfam: Normal lung function maintenance, Low in Lung Cancer 1 protein [PF14945.8, score=30.4]} {Human: ENSG00000150873, C2orf50, chromosome 2 open reading frame 50, [RH, Score=73.2, Expect=1e-16]} {Mouse: ENSMUSG00000071398, 2410004P03Rik, RIKEN cDNA 2410004P03 gene, [RH, Score=79.0, Expect=4e-19]} {Smed: dd_Smed_v6_6024_0_1, dd_Smed_v6_6024_0_1, [RH, Score=115, Expect=6e-34]} {RNA1509_4568} {RNA1310_56366} {RNA815_28077}

Mlig455_014169 {REF} {Length: 879} {Pfam: Normal lung function maintenance, Low in Lung Cancer 1 protein [PF14945.8, score=31.6]} {Human: ENSG00000150873, C2orf50, chromosome 2 open reading frame 50, [Score=53.9, Expect=1e-09]} {Mouse: ENSMUSG00000071398, 2410004P03Rik, RIKEN cDNA 2410004P03 gene, [Score=54.7, Expect=2e-10]} {Smed: dd_Smed_v6_6024_0_1, dd_Smed_v6_6024_0_1, [Score=81.3, Expect=9e-21]} {RNA1509_4568} {RNA1310_56366, RNA1509_4568} {RNA1509_4568, RNA815_28077}
51. MligTC455_42951 2071 43.15 Mlig455_052754

Neo: -

Age: logFC(26M/2M)=-0.385

 0.957 - - - - - 0.957 Mlig455_052754 {REF} {Length: 3346} {TRANSSPLICED} {Smed: dd_Smed_v6_4966_0_1, dd_Smed_v6_4966_0_1, [Score=55.5, Expect=4e-08]} {RNA1509_24062, RNA1509_28933, RNA1509_29774, RNA1509_36845, RNA1509_5687} {RNA1310_19105, RNA1509_24062, RNA1509_28933, RNA1509_29774, RNA1509_36845, RNA1509_5687} {RNA1509_24062, RNA1509_28933, RNA1509_29774, RNA1509_36845, RNA1509_5687, RNA815_8910.1}
52. MligTC455_32685 505 10.53 Mlig455_057075

Neo: -

Age: Up-Down-Up

 0.956 - - - - - 0.956 Mlig455_057075 {REF} {Length: 7466} {Pfam: REJ domain [PF02010.17, score=62.8]} {RNA1509_14190, RNA1509_21224, RNA1509_37446, RNA1509_40150} {RNA1310_402.1, RNA1509_14190, RNA1509_21224, RNA1509_37446, RNA1509_40150} {RNA1509_14190, RNA1509_21224, RNA1509_37446, RNA1509_40150, RNA815_93.1}
53. MligTC455_48388 631 13.15 Mlig455_050431

Neo: -

Age: -

 DPYSL2 0.955 0.955 - - - - - Mlig455_050431 {REF} {Length: 2733} {TRANSSPLICED} {Pfam: Amidohydrolase family [PF01979.22, score=92.6]; Amidohydrolase family [PF07969.13, score=43.6]; Amidohydrolase [PF04909.16, score=27.3]} {Human: ENSG00000092964, DPYSL2, dihydropyrimidinase like 2, [Score=520, Expect=2e-179]; ENSG00000072832, CRMP1, collapsin response mediator protein 1, [Score=518, Expect=1e-178]; ENSG00000113657, DPYSL3, dihydropyrimidinase like 3, [Score=511, Expect=9e-176]; ENSG00000151640, DPYSL4, dihydropyrimidinase like 4, [Score=499, Expect=3e-171]} {Mouse: ENSMUSG00000022048, Dpysl2, dihydropyrimidinase-like 2, [Score=523, Expect=1e-180]; ENSMUSG00000029121, Crmp1, collapsin response mediator protein 1, [Score=522, Expect=3e-180]; ENSMUSG00000024501, Dpysl3, dihydropyrimidinase-like 3, [Score=509, Expect=2e-175]; ENSMUSG00000025478, Dpysl4, dihydropyrimidinase-like 4, [Score=501, Expect=4e-172]; ENSMUSG00000111393, Dpysl4, dihydropyrimidinase-like 4, [Score=501, Expect=4e-172]} {Dmel: FBgn0023023, CRMP, Collapsin Response Mediator Protein, [Score=509, Expect=3e-175]} {Celegans: WBGene00000964, dhp-2, Dihydropyrimidinase 2, [Score=448, Expect=2e-152]} {Smed: dd_Smed_v6_1478_0_1, dd_Smed_v6_1478_0_1, [Score=661, Expect=0.0]} {RNA1509_26733} {RNA1310_11824, RNA1509_26733} {RNA1509_26733, RNA815_4512}
54. MligTC455_21158 748 15.59 Mlig455_009127, Mlig455_058069

Neo: -

Age: Down-Down-Up

 0.953 0.953 - - - - -

Mlig455_009127 {REF} {Length: 2585} {Smed: dd_Smed_v6_9937_0_1, dd_Smed_v6_9937_0_1, [RH, Score=234, Expect=4e-72]} {RNA1509_12143} {RNA1310_1205.1} {RNA815_1842.1}

Mlig455_058069 {REF} {Length: 3231} {Smed: dd_Smed_v6_9937_0_1, dd_Smed_v6_9937_0_1, [RH, Score=236, Expect=1e-72]} {RNA1509_12143, RNA1509_45170} {RNA1310_1205.1, RNA1509_12143, RNA1509_45170} {RNA1509_12143, RNA1509_45170, RNA815_1842.1}
55. MligTC455_34927 451 9.4 Mlig455_049016

Neo: -

Age: logFC(26M/2M)=-0.304

 0.953 0.953 - - - - - Mlig455_049016 {REF} {Length: 1741} {RNA1509_22221} {RNA1310_17396.1, RNA1509_22221} {RNA1509_22221, RNA815_24978}
56. MligTC455_32561 507 10.57 Mlig455_005261

Neo: -

Age: logFC(26M/2M)=-0.281

 NWD2 0.952 - - - - - 0.952 Mlig455_005261 {REF} {Length: 6130} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=172, Expect=3e-42]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=159, Expect=2e-38]} {Dmel: FBgn0038397, CG10185, [Score=226, Expect=3e-59]} {Celegans: WBGene00020254, T05C3.2, [Score=233, Expect=3e-61]} {Smed: dd_Smed_v6_9637_0_1, dd_Smed_v6_9637_0_1, [RH, Score=669, Expect=0.0]} {RNA1509_2854, RNA1509_32196, RNA1509_40786} {RNA1310_588, RNA1509_2854, RNA1509_32196, RNA1509_40786} {RNA1509_2854, RNA1509_32196, RNA1509_40786, RNA815_179}
57. MligTC455_34641 301 6.27 Mlig455_027038

Neo: -

Age: -

 ATP2A1 0.951 0.951 - - - - - Mlig455_027038 {REF} {Length: 4352} {TRANSSPLICED} {Pfam: E1-E2 ATPase [PF00122.22, score=191.8]; Cation transporting ATPase, C-terminus [PF00689.23, score=146.4]; Cation transport ATPase (P-type) [PF13246.8, score=76.4]; haloacid dehalogenase-like hydrolase [PF00702.28, score=73.8]; Cation transporter/ATPase, N-terminus [PF00690.28, score=67.0]; haloacid dehalogenase-like hydrolase [PF12710.9, score=30.5]; haloacid dehalogenase-like hydrolase [PF08282.14, score=30.2]} {Human: ENSG00000196296, ATP2A1, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, [RH, Score=1462, Expect=0.0]; ENSG00000174437, ATP2A2, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2, [RH, Score=1446, Expect=0.0]; ENSG00000074370, ATP2A3, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3, [RH, Score=1403, Expect=0.0]} {Mouse: ENSMUSG00000030730, Atp2a1, ATPase, Ca++ transporting, cardiac muscle, fast twitch 1, [RH, Score=1456, Expect=0.0]; ENSMUSG00000029467, Atp2a2, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2, [RH, Score=1450, Expect=0.0]; ENSMUSG00000020788, Atp2a3, ATPase, Ca++ transporting, ubiquitous, [RH, Score=1404, Expect=0.0]} {Dmel: FBgn0263006, SERCA, Sarco/endoplasmic reticulum Ca(2+)-ATPase, [RH, Score=1493, Expect=0.0]} {Celegans: WBGene00004736, sca-1, Calcium-transporting ATPase, [RH, Score=1466, Expect=0.0]} {Smed: dd_Smed_v6_1772_0_1, dd_Smed_v6_1772_0_1, [RH, Score=1613, Expect=0.0]} {RNA1509_20343} {RNA1310_3029.1} {RNA815_2104.2}
58. MligTC455_47441 543 11.32 Mlig455_045866

Neo: -

Age: -

 0.951 0.951 - - - - - Mlig455_045866 {REF} {Length: 2993} {TRANSSPLICED} {Smed: dd_Smed_v6_11834_0_1, dd_Smed_v6_11834_0_1, [RH, Score=173, Expect=4e-47]} {RNA1509_34658, RNA1509_4754} {RNA1310_5693.1, RNA1509_34658, RNA1509_4754} {RNA1509_34658, RNA1509_4754, RNA815_2001}
59. MligTC455_19179 442 9.21 Mlig455_059343

Neo: -

Age: Up-Down-Up

 0.95 0.950 - - - - - Mlig455_059343 {REF} {Length: 1621} {Smed: dd_Smed_v6_5147_0_1, dd_Smed_v6_5147_0_1, [RH, Score=62.8, Expect=2e-11]} {RNA1509_38428} {RNA1310_38164} {RNA815_17603}
60. MligTC455_39652 1049 21.85 Mlig455_036203

Neo: -

Age: Up-Up-Down

Regeneration-downregulated BL: -1.979

Regeneration-depleted BL: -1.979

 RNF217 0.95 0.950 - - - - - Mlig455_036203 {REF} {Length: 5439} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=50.6]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=166, Expect=1e-44]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=163, Expect=5e-44]} {Dmel: FBgn0025186, ari-2, ariadne 2, [Score=68.6, Expect=5e-12]} {Celegans: WBGene00016156, C27A12.6, [Score=72.0, Expect=3e-13]} {Smed: dd_Smed_v6_7110_0_1, dd_Smed_v6_7110_0_1, [Score=128, Expect=8e-32]} {RNA1509_19339, RNA1509_41201, RNA1509_57487} {RNA1310_11553.2, RNA1509_19339, RNA1509_41201, RNA1509_57487} {RNA1509_19339, RNA1509_41201, RNA1509_57487, RNA815_5548}
61. MligTC455_50125 1313 27.35 Mlig455_004438

Neo: -

Age: logFC(26M/2M)=-0.404

Regeneration-upregulated R5: 1.629

Regeneration-enriched R5: 1.629

 DNASE2B 0.95 0.950 - - - - - Mlig455_004438 {REF} {Length: 2450} {Pfam: Deoxyribonuclease II [PF03265.17, score=271.5]} {Human: ENSG00000137976, DNASE2B, deoxyribonuclease 2 beta, [RH, Score=163, Expect=8e-46]; ENSG00000105612, DNASE2, deoxyribonuclease 2, lysosomal, [RH, Score=160, Expect=6e-45]} {Mouse: ENSMUSG00000003812, Dnase2a, deoxyribonuclease II alpha, [RH, Score=170, Expect=8e-49]} {Dmel: FBgn0000477, DNaseII, Deoxyribonuclease II, [RH, Score=132, Expect=9e-35]} {Celegans: WBGene00003828, nuc-1, Deoxyribonuclease-2, [RH, Score=172, Expect=7e-50]} {Smed: dd_Smed_v6_1643_0_1, dd_Smed_v6_1643_0_1, [RH, Score=172, Expect=4e-50]} {RNA1509_8025} {RNA1310_8215.2, RNA1509_8025} {RNA1509_8025, RNA815_4592.1}

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