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Results for MligTC455_23371

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_23371 101 2.11 Mlig455_006907

Neo: -

Age: Down-Up-Down

Region-enriched R8: 3.403/0.01276

FSTL1 Mlig455_006907 {REF} {Length: 3700} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=60.0]; Immunoglobulin domain [PF13927.8, score=59.2]; Kazal-type serine protease inhibitor domain [PF07648.17, score=42.0]; Immunoglobulin domain [PF13895.8, score=33.6]; Immunoglobulin domain [PF00047.27, score=32.3]; Kazal-type serine protease inhibitor domain [PF00050.23, score=28.7]; Immunoglobulin V-set domain [PF07686.19, score=27.7]} {Human: ENSG00000163430, FSTL1, follistatin like 1, [RH, Score=68.9, Expect=3e-13]} {Mouse: ENSMUSG00000022816, Fstl1, follistatin-like 1, [RH, Score=68.2, Expect=6e-12]} {Celegans: WBGene00004256, pxn-1, Peroxidasin homolog, [Score=51.2, Expect=3e-06]} {RNA1509_41764} {RNA1310_9313, RNA1509_41764} {RNA1509_41764, RNA815_25649}

Cumulative graph for MligTC455_23371

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.082 1.63 0.96891 1.00000
RegionR2 2.367 1.63 0.00675 0.07823
RegionR3 -0.579 1.63 0.50149 0.99505
RegionR4 -2.777 1.63 0.00747 0.04903
RegionR5 -3.408 1.63 0.00069 0.00757
RegionR6 -0.25 1.63 0.79919 1.00000
RegionR7 1.163 1.63 0.23836 0.86289
RegionR8 3.403 1.63 0.00017 0.01276

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -4.344 1.63 0.50135 1.00000
RegenerationR2 -1.008 1.63 0.12141 0.54112
RegenerationR3 0.464 1.63 0.62116 0.91710
RegenerationR4 -0.093 1.63 0.90488 1.00000
RegenerationR5 1.235 1.63 0.26577 0.69730
RegenerationR6 -1.047 1.63 0.32341 0.66964
RegenerationBL -2.196 1.63 0.09625 0.36382
RegenerationTP -2.117 1.63 0.06235 0.40412


Genes with expression patterns similar to MligTC455_23371

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_23371 101 2.11 Mlig455_006907

Neo: -

Age: Down-Up-Down

Region-enriched R8: 3.403/0.01276

FSTL1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_006907 {REF} {Length: 3700} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=60.0]; Immunoglobulin domain [PF13927.8, score=59.2]; Kazal-type serine protease inhibitor domain [PF07648.17, score=42.0]; Immunoglobulin domain [PF13895.8, score=33.6]; Immunoglobulin domain [PF00047.27, score=32.3]; Kazal-type serine protease inhibitor domain [PF00050.23, score=28.7]; Immunoglobulin V-set domain [PF07686.19, score=27.7]} {Human: ENSG00000163430, FSTL1, follistatin like 1, [RH, Score=68.9, Expect=3e-13]} {Mouse: ENSMUSG00000022816, Fstl1, follistatin-like 1, [RH, Score=68.2, Expect=6e-12]} {Celegans: WBGene00004256, pxn-1, Peroxidasin homolog, [Score=51.2, Expect=3e-06]} {RNA1509_41764} {RNA1310_9313, RNA1509_41764} {RNA1509_41764, RNA815_25649}
2. MligTC455_19583 95 1.97 Mlig455_010583, Mlig455_010602

Neo: -

Age: -

Region-enriched R2: 6.442/0.00383

2.768 - - 0.955 0.838 - 0.975

Mlig455_010583 {REF} {Length: 2325} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=173.5]} {Smed: dd_Smed_v6_23771_0_1, dd_Smed_v6_23771_0_1, [Score=320, Expect=4e-101]} {RNA1310_36131} {RNA815_32135}

Mlig455_010602 {REF} {Length: 2432} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=182.9]} {Smed: dd_Smed_v6_15099_0_1, dd_Smed_v6_15099_0_1, [RH, Score=346, Expect=2e-110]} {RNA1310_36131} {RNA815_32135}
3. MligTC455_54035 84 1.74 Mlig455_017217

Neo: -

Age: Down-Up-Down

CALML5 2.705 0.909 - 0.971 0.825 - - Mlig455_017217 {REF} {Length: 1760} {Pfam: EF hand [PF00036.34, score=48.2]; EF-hand domain pair [PF13499.8, score=45.0]; EF-hand domain [PF13405.8, score=40.7]; EF hand [PF13202.8, score=34.7]; EF-hand domain pair [PF13833.8, score=29.2]} {Human: ENSG00000178372, CALML5, calmodulin like 5, [Score=50.4, Expect=7e-08]} {Mouse: ENSMUSG00000097733, Cabp2, calcium binding protein 2, [Score=45.8, Expect=5e-06]; ENSMUSG00000024857, Cabp2, calcium binding protein 2, [Score=45.8, Expect=5e-06]} {Celegans: WBGene00000287, cal-3, CALmodulin related genes, [Score=50.4, Expect=7e-08]} {Smed: dd_Smed_v6_4512_0_1, dd_Smed_v6_4512_0_1, [Score=45.8, Expect=2e-06]} {RNA1509_44750} {RNA1310_71381} {RNA815_19875}
4. MligTC455_45496 144 2.99 Mlig455_010048

Neo: -

Age: Up-Down-Up

Region-enriched R2: 3.720/0.00332

CAV2 2.633 0.856 - - - 0.811 0.966 Mlig455_010048 {REF} {Length: 2607} {Pfam: Caveolin [PF01146.19, score=125.0]} {Human: ENSG00000105971, CAV2, caveolin 2, [Score=85.5, Expect=3e-21]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [Score=89.4, Expect=7e-23]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=79.0, Expect=2e-18]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=153, Expect=1e-48]} {RNA1509_20287} {RNA1310_50581.1, RNA1509_20287} {RNA1509_20287, RNA815_31873}
5. MligTC455_16000 46 0.97 Mlig455_015523

Neo: -

Age: -

2.579 - - - 0.800 0.827 0.952 Mlig455_015523 {REF} {Length: 2952}
6. MligTC455_33132 332 6.91 Mlig455_030500, Mlig455_030509

Neo: -

Age: Up-Down-Down

ELOVL4 2.571 0.957 - - 0.712 - 0.902

Mlig455_030500 {REF} {Length: 2762} {Pfam: GNS1/SUR4 family [PF01151.20, score=210.2]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [Score=285, Expect=1e-95]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [Score=284, Expect=3e-95]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [RH, Score=220, Expect=7e-71]} {Celegans: WBGene00001245, elo-7, Elongation of very long chain fatty acids protein, [Score=84.7, Expect=9e-19]} {Smed: dd_Smed_v6_15507_0_1, dd_Smed_v6_15507_0_1, [RH, Score=321, Expect=3e-110]} {RNA1310_23275} {RNA815_27528}

Mlig455_030509 {REF} {Length: 2649} {Pfam: Helix-turn-helix domain of transposase family ISL3 [PF13542.8, score=27.8]} {RNA1509_53064} {RNA1310_51836} {RNA815_4493}
7. MligTC455_23621 323 6.72 Mlig455_039694, Mlig455_039749

Neo: -

Age: -

Region-enriched R2: 2.235/0.02499

2.568 0.906 - 0.707 - - 0.955

Mlig455_039694 {REF} {Length: 2054} {RNA1509_29694} {RNA1310_14789} {RNA815_12997}

Mlig455_039749 {REF} {Length: 1751} {RNA1509_29694} {RNA1310_14789, RNA1509_29694} {RNA1509_29694, RNA815_12997}
8. MligTC455_34525 52 1.08 Mlig455_021566

Neo: -

Age: Down-Up-Down

GNAI1 2.568 - 0.790 - 0.827 - 0.951 Mlig455_021566 {REF} {Length: 3532} {Pfam: G-protein alpha subunit [PF00503.22, score=404.9]; ADP-ribosylation factor family [PF00025.23, score=56.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=20.1]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.4]} {Human: ENSG00000127955, GNAI1, G protein subunit alpha i1, [Score=486, Expect=2e-171]; ENSG00000114353, GNAI2, G protein subunit alpha i2, [Score=481, Expect=3e-169]; ENSG00000065135, GNAI3, G protein subunit alpha i3, [Score=474, Expect=1e-166]} {Mouse: ENSMUSG00000057614, Gnai1, guanine nucleotide binding protein (G protein), alpha inhibiting 1, [Score=486, Expect=2e-171]; ENSMUSG00000032562, Gnai2, guanine nucleotide binding protein (G protein), alpha inhibiting 2, [Score=475, Expect=5e-167]; ENSMUSG00000000001, Gnai3, guanine nucleotide binding protein (G protein), alpha inhibiting 3, [Score=474, Expect=1e-166]} {Dmel: FBgn0001104, Galphai, G protein alpha i subunit, [Score=468, Expect=2e-164]} {Celegans: WBGene00001648, goa-1, Guanine nucleotide-binding protein G(o) subunit alpha, [Score=446, Expect=5e-156]} {Smed: dd_Smed_v6_12112_0_1, dd_Smed_v6_12112_0_1, [RH, Score=598, Expect=0.0]} {RNA1509_45426} {RNA1310_26920, RNA1509_45426} {RNA1509_45426, RNA815_11718}
9. MligTC455_52788 41 0.86 Mlig455_016296

Neo: -

Age: -

FCN1 2.546 - - 0.986 0.727 - 0.833 Mlig455_016296 {REF} {Length: 1559} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=167.4]} {Human: ENSG00000085265, FCN1, ficolin 1, [Score=141, Expect=2e-39]; ENSG00000160339, FCN2, ficolin 2, [Score=139, Expect=3e-39]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=134, Expect=2e-35]} {Mouse: ENSMUSG00000026938, Fcna, ficolin A, [RH, Score=135, Expect=4e-37]} {Dmel: FBgn0003326, sca, scabrous, [RH, Score=128, Expect=4e-33]} {Celegans: WBGene00020516, T15B7.1, [Score=59.3, Expect=6e-10]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=110, Expect=4e-27]} {RNA1310_57278} {RNA815_33549}
10. MligTC455_47525 119 2.49 Mlig455_030977

Neo: -

Age: Down-Up-Up

Region-enriched R2: 3.232/0.02097

CALM2 2.523 - - 0.971 - 0.808 0.744 Mlig455_030977 {REF} {Length: 1161} {Pfam: EF hand [PF00036.34, score=76.5]; EF-hand domain pair [PF13499.8, score=73.7]; EF-hand domain [PF13405.8, score=66.7]; EF-hand domain [PF14658.8, score=42.2]; EF hand [PF13202.8, score=35.1]; EF-hand domain pair [PF13833.8, score=33.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=30.9]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=151, Expect=4e-47]; ENSG00000198668, CALM1, calmodulin 1, [Score=151, Expect=4e-47]; ENSG00000160014, CALM3, calmodulin 3, [Score=151, Expect=4e-47]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=151, Expect=3e-47]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=151, Expect=3e-47]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=151, Expect=3e-47]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=152, Expect=8e-48]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=151, Expect=1e-47]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=151, Expect=1e-47]} {RNA1310_31633} {RNA815_34040}
11. MligTC455_52656 121 2.51 Mlig455_062381, Mlig455_062408

Neo: -

Age: Down-Up-Down

2.52 0.740 - - 0.826 - 0.954

Mlig455_062381 {REF} {Length: 2245} {RNA1310_26272} {RNA815_22826}

Mlig455_062408 {REF} {Length: 2277} {RNA1310_26272} {RNA815_37592}
12. MligTC455_24302 149 3.11 Mlig455_035632

Neo: -

Age: Up-Down-Up

KCNQ5 2.516 0.779 - - 0.779 - 0.958 Mlig455_035632 {REF} {Length: 2263} {Pfam: KCNQ voltage-gated potassium channel [PF03520.16, score=124.6]} {Human: ENSG00000185760, KCNQ5, potassium voltage-gated channel subfamily Q member 5, [Score=122, Expect=1e-28]; ENSG00000117013, KCNQ4, potassium voltage-gated channel subfamily Q member 4, [Score=121, Expect=2e-28]} {Mouse: ENSMUSG00000028033, Kcnq5, potassium voltage-gated channel, subfamily Q, member 5, [Score=121, Expect=1e-28]; ENSMUSG00000028631, Kcnq4, potassium voltage-gated channel, subfamily Q, member 4, [Score=119, Expect=4e-28]} {Dmel: FBgn0033494, KCNQ, KCNQ potassium channel, [Score=175, Expect=1e-46]} {Celegans: WBGene00002235, kqt-3, KQT-3 potassium channel; Potassium channel, KvQLT family, [Score=110, Expect=1e-25]} {Smed: dd_Smed_v6_17359_0_2, dd_Smed_v6_17359_0_2, [Score=186, Expect=2e-52]} {RNA1509_34272} {RNA1310_3730.1} {RNA815_2787}
13. MligTC455_43173 392 8.16 Mlig455_037383

Neo: -

Age: Up-Down-Down

Regeneration-downregulated TP: -5.031

Regeneration-depleted TP: -5.031

C2orf16 2.507 - 0.773 - 0.775 - 0.959 Mlig455_037383 {REF} {Length: 2450} {Pfam: Cornifin (SPRR) family [PF02389.17, score=23.4]} {Human: ENSG00000221843, C2orf16, chromosome 2 open reading frame 16, [Score=80.1, Expect=7e-15]} {RNA1509_52401} {RNA1310_14622.1} {RNA815_17994}
14. MligTC455_41036 281 5.86 Mlig455_057198

Neo: -

Age: -

Region-specific R2: 5.284

Region-enriched R2: 4.243/0.00075

2.481 - - - 0.788 0.731 0.962 Mlig455_057198 {REF} {Length: 538} {Pfam: Pancreatic hormone peptide [PF00159.20, score=41.9]} {RNA1509_42071} {RNA1310_74103, RNA1509_42071} {RNA1509_42071, RNA815_38377}
15. MligTC455_41396 187 3.9 Mlig455_012937, Mlig455_031470

Neo: -

Age: -

Region-enriched R2: 4.167/0.01146

2.461 0.746 - - 0.761 - 0.954

Mlig455_012937 {REF} {Length: 1911} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [Score=46.6, Expect=1e-06]} {RNA1509_16138} {RNA1310_24329} {RNA815_11818}

Mlig455_031470 {REF} {Length: 1745} {Dmel: FBgn0083971, CG34135, [RH, Score=60.1, Expect=1e-10]} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [RH, Score=96.3, Expect=3e-23]} {RNA1509_16138} {RNA1310_24329} {RNA815_11818}
16. MligTC455_19456 34 0.7 Mlig455_038677

Neo: -

Age: -

2.444 - - - 0.779 0.714 0.951 Mlig455_038677 {REF} {Length: 1621} {TRANSSPLICED} {Smed: dd_Smed_v6_15258_0_1, dd_Smed_v6_15258_0_1, [Score=49.3, Expect=4e-07]} {RNA1310_112748}
17. MligTC455_25408 35 0.72 Mlig455_026127

Neo: -

Age: Up-Down-Down

1.905 - - - - 0.928 0.977 Mlig455_026127 {REF} {Length: 2873} {Pfam: Variant SH3 domain [PF07653.19, score=21.9]; RIM-binding protein of the cytomatrix active zone [PF10174.11, score=16.9]} {Mouse: ENSMUSG00000034156, Tspoap1, TSPO associated protein 1, [Score=55.1, Expect=4e-07]} {Smed: dd_Smed_v6_14584_0_1, dd_Smed_v6_14584_0_1, [Score=140, Expect=5e-35]} {RNA1509_45271} {RNA1310_5741} {RNA815_46868}
18. MligTC455_40878 355 7.39 Mlig455_014130

Neo: -

Age: -

1.884 0.934 - - - - 0.950 Mlig455_014130 {REF} {Length: 1465} {RNA1509_7458} {RNA1310_36212} {RNA815_1610.1}
19. MligTC455_47712 80 1.66 Mlig455_044833

Neo: -

Age: -

1.858 - - - 0.883 - 0.975 Mlig455_044833 {REF} {Length: 564} {RNA1509_55855} {RNA1310_87612} {RNA815_50831}
20. MligTC455_29169 108 2.25 Mlig455_002330

Neo: -

Age: Up-Down-Down

DNAH5 1.857 0.905 - - - - 0.952 Mlig455_002330 {REF} {Length: 14879} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=576.9]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=466.5]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=429.5]; Dynein heavy chain C-terminal domain [PF18199.3, score=313.2]; P-loop containing dynein motor region D4 [PF12780.9, score=303.1]; ATP-binding dynein motor region [PF12781.9, score=290.8]; P-loop containing dynein motor region [PF12775.9, score=229.8]; Dynein heavy chain AAA lid domain [PF18198.3, score=179.2]; Microtubule-binding stalk of dynein motor [PF12777.9, score=144.8]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=121.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=75.6]; Dynein heavy chain AAA lid domain [PF17852.3, score=70.5]; AAA+ lid domain [PF17857.3, score=60.9]; AAA ATPase domain [PF13191.8, score=21.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=21.3]; P-loop containing region of AAA domain [PF13555.8, score=20.3]} {Human: ENSG00000039139, DNAH5, dynein axonemal heavy chain 5, [RH, Score=6256, Expect=0.0]} {Mouse: ENSMUSG00000022262, Dnah5, dynein, axonemal, heavy chain 5, [RH, Score=6232, Expect=0.0]} {Dmel: FBgn0037726, CG9492, [RH, Score=5094, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=1294, Expect=0.0]} {Smed: dd_Smed_v6_4569_0_1, dd_Smed_v6_4569_0_1, [RH, Score=6936, Expect=0.0]} {RNA1509_39171, RNA1509_51275} {RNA1310_408, RNA1509_39171} {RNA1509_39171, RNA815_44.1}
21. MligTC455_26861 362 7.55 Mlig455_033415, Mlig455_064795

Neo: -

Age: -

1.835 - - - - 0.953 0.882

Mlig455_033415 {REF} {Length: 1405} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4562) [PF15123.8, score=21.1]} {RNA1509_57859} {RNA1310_48970} {RNA815_25953}

Mlig455_064795 {REF} {Length: 590} {NoTransDecoderORF} {RNA1509_53699} {RNA1310_65460, RNA1509_53699} {RNA1509_53699, RNA815_61504}
22. MligTC455_33832 112 2.34 Mlig455_029411

Neo: -

Age: Up-Down-Down

Region-enriched R2: 5.300/0.00016
Region-enriched R8: 4.136/0.03070

GLRA3 1.832 0.868 - - - - 0.964 Mlig455_029411 {REF} {Length: 3686} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=149.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=84.5]} {Human: ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=257, Expect=5e-80]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=253, Expect=3e-78]; ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=250, Expect=4e-77]} {Mouse: ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=251, Expect=2e-77]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=249, Expect=5e-77]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=248, Expect=2e-76]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=243, Expect=1e-74]} {Dmel: FBgn0024963, GluClalpha, [Score=253, Expect=2e-78]} {Celegans: WBGene00000233, avr-15, GluClalpha2B protein, [Score=259, Expect=7e-81]} {Smed: dd_Smed_v6_11342_0_1, dd_Smed_v6_11342_0_1, [RH, Score=480, Expect=1e-167]} {RNA1509_35986} {RNA1310_35528} {RNA815_35433}
23. MligTC455_49876 127 2.65 Mlig455_027453

Neo: -

Age: -

Region-enriched R7: 3.060/0.03738

CHRNA10 1.827 - - 0.876 - - 0.951 Mlig455_027453 {REF} {Length: 1472} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=86.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=24.5]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=70.1, Expect=7e-13]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=69.7, Expect=6e-13]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=74.7, Expect=1e-14]} {Celegans: WBGene00000057, acr-18, AcetylCholine Receptor; Acetylcholine receptor, one of nine alpha a7-like nicotinic acetylcholine receptor subunits (58.6 kD) (Acr-18), [Score=71.6, Expect=9e-14]} {Smed: dd_Smed_v6_11955_0_1, dd_Smed_v6_11955_0_1, [Score=72.0, Expect=6e-14]} {RNA1310_60993} {RNA815_7952}
24. MligTC455_41295 203 4.23 Mlig455_007836

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.543

1.825 - - - 0.960 - 0.865 Mlig455_007836 {REF} {Length: 2189} {RNA1509_59262} {RNA1310_31928, RNA1509_59262} {RNA1509_59262, RNA815_32415}
25. MligTC455_40065 58 1.22 Mlig455_069280

Neo: -

Age: Up-Down-Up

1.822 - - 0.853 - - 0.969 Mlig455_069280 {REF} {Length: 3092} {Pfam: Coiled-coil domain-containing protein 154 [PF15450.8, score=35.7]; Apolipoprotein A1/A4/E domain [PF01442.20, score=19.3]} {Smed: dd_Smed_v6_10236_0_1, dd_Smed_v6_10236_0_1, [Score=236, Expect=1e-67]} {RNA1509_48196} {RNA1310_30411, RNA1509_48196} {RNA1509_48196, RNA815_45200}
26. MligTC455_37315 84 1.76 Mlig455_048842

Neo: -

Age: -

CALM2 1.819 - - - 0.864 - 0.955 Mlig455_048842 {REF} {Length: 1287} {Pfam: EF-hand domain pair [PF13499.8, score=22.7]; EF-hand domain [PF14658.8, score=19.6]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=68.9, Expect=6e-14]; ENSG00000198668, CALM1, calmodulin 1, [Score=68.2, Expect=4e-14]; ENSG00000160014, CALM3, calmodulin 3, [Score=66.6, Expect=2e-13]; ENSG00000178363, CALML3, calmodulin like 3, [Score=65.5, Expect=4e-13]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=67.0, Expect=2e-13]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=66.6, Expect=1e-13]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=66.6, Expect=1e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=68.6, Expect=1e-14]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=68.6, Expect=1e-14]} {Smed: dd_Smed_v6_5491_0_1, dd_Smed_v6_5491_0_1, [Score=110, Expect=3e-30]} {RNA1310_33365} {RNA815_27013}
27. MligTC455_46451 229 4.76 Mlig455_017183

Neo: -

Age: Down-Up-Down

Region-specific R2: 5.510

Region-enriched R2: 5.394/0.00018

Regeneration-downregulated R2: -2.986

Regeneration-depleted R2: -2.986

1.813 - - - 0.855 - 0.958 Mlig455_017183 {REF} {Length: 657} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.6]} {RNA1310_62963} {RNA815_31352}
28. MligTC455_26601 40 0.84 Mlig455_000748

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.661

1.811 - - 0.844 - - 0.967 Mlig455_000748 {REF} {Length: 4122} {Smed: dd_Smed_v6_17076_0_2, dd_Smed_v6_17076_0_2, [Score=84.3, Expect=1e-17]} {RNA1310_16747.1} {RNA815_12493}
29. MligTC455_17363 62 1.28 Mlig455_003936

Neo: -

Age: -

1.808 - - - 0.848 - 0.960 Mlig455_003936 {REF} {Length: 1252} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=45.9]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=26.4]} {RNA1310_47889} {RNA815_24646}
30. MligTC455_51051 233 4.85 Mlig455_046293

Neo: -

Age: -

1.808 0.849 - - - - 0.959 Mlig455_046293 {REF} {Length: 1585} {RNA1310_32253}
31. MligTC455_53333 44 0.91 Mlig455_019019, Mlig455_055684

Neo: -

Age: Up-Down-Up

Region-enriched R4: 4.725/0.03950

CHRNA7 1.803 - - - 0.826 - 0.977

Mlig455_019019 {REF} {Length: 2615} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=154.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=93.9]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=210, Expect=2e-59]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=208, Expect=5e-59]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=207, Expect=8e-59]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=206, Expect=3e-58]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=209, Expect=1e-59]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=205, Expect=3e-58]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=221, Expect=3e-63]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=190, Expect=7e-53]} {Smed: dd_Smed_v6_9503_0_1, dd_Smed_v6_9503_0_1, [Score=426, Expect=5e-142]} {RNA1509_56207} {RNA1310_26355} {RNA815_26644}

Mlig455_055684 {REF} {Length: 2604} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=154.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=94.7]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=211, Expect=9e-60]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=209, Expect=3e-59]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=208, Expect=5e-59]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=207, Expect=7e-59]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=209, Expect=9e-60]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=204, Expect=1e-57]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=222, Expect=1e-63]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=190, Expect=6e-53]} {Smed: dd_Smed_v6_9503_0_1, dd_Smed_v6_9503_0_1, [Score=427, Expect=3e-142]} {RNA1509_56207} {RNA1310_26355} {RNA815_26644}
32. MligTC455_50099 170 3.55 Mlig455_030606, Mlig455_030681

Neo: -

Age: Up-Down-Down

SLC4A11 1.802 - - - 0.833 - 0.969

Mlig455_030606 {REF} {Length: 3525} {Pfam: HCO3- transporter family [PF00955.23, score=528.0]; Band 3 cytoplasmic domain [PF07565.15, score=23.9]; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 [PF00359.24, score=22.2]} {Human: ENSG00000088836, SLC4A11, solute carrier family 4 member 11, [RH, Score=553, Expect=0.0]} {Mouse: ENSMUSG00000074796, Slc4a11, solute carrier family 4, sodium bicarbonate transporter-like, member 11, [RH, Score=540, Expect=2e-179]} {Dmel: FBgn0259111, Ndae1, Na[+]-driven anion exchanger 1, [Score=239, Expect=4e-66]} {Celegans: WBGene00019018, abts-3, Anion transporter ABTS-3; Anion/Bicarbonate TranSporter family, [RH, Score=685, Expect=0.0]} {Smed: dd_Smed_v6_16577_0_1, dd_Smed_v6_16577_0_1, [RH, Score=899, Expect=0.0]} {RNA1509_55902} {RNA1310_18543} {RNA815_14015}

Mlig455_030681 {REF} {Length: 2174} {Pfam: HCO3- transporter family [PF00955.23, score=526.7]; Band 3 cytoplasmic domain [PF07565.15, score=23.8]; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 [PF00359.24, score=22.0]} {Human: ENSG00000088836, SLC4A11, solute carrier family 4 member 11, [RH, Score=547, Expect=3e-180]} {Mouse: ENSMUSG00000074796, Slc4a11, solute carrier family 4, sodium bicarbonate transporter-like, member 11, [RH, Score=533, Expect=2e-175]} {Dmel: FBgn0259111, Ndae1, Na[+]-driven anion exchanger 1, [Score=242, Expect=3e-66]} {Celegans: WBGene00019018, abts-3, Anion transporter ABTS-3; Anion/Bicarbonate TranSporter family, [RH, Score=680, Expect=0.0]} {Smed: dd_Smed_v6_16577_0_1, dd_Smed_v6_16577_0_1, [RH, Score=904, Expect=0.0]} {RNA1509_55902} {RNA1310_18543} {RNA815_14015}
33. MligTC455_17178 54 1.12 Mlig455_067758

Neo: -

Age: -

Region-enriched R2: 7.471/0.00007

1.797 - - - 0.821 - 0.976 Mlig455_067758 {REF} {Length: 2301} {RNA1509_44702} {RNA1310_14743} {RNA815_20669.1}
34. MligTC455_43715 48 0.99 Mlig455_034191

Neo: -

Age: Down-Up-Down

Region-enriched R2: 7.969/0.00817

1.796 - - - 0.836 - 0.960 Mlig455_034191 {REF} {Length: 895} {Pfam: WSC domain [PF01822.21, score=39.9]; PAN domain [PF14295.8, score=21.0]; PAN domain [PF00024.28, score=19.9]} {RNA1310_46313} {RNA815_23250}
35. MligTC455_38949 105 2.19 Mlig455_065209

Neo: -

Age: -

Region-specific R2: 7.633

Region-enriched R2: 10.088/0.00000

1.795 - - - 0.832 - 0.963 Mlig455_065209 {REF} {Length: 591} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=23.2]} {RNA1509_44618} {RNA1310_63839, RNA1509_44618} {RNA1509_44618, RNA815_35329}
36. MligTC455_44966 574 11.95 Mlig455_036578, Mlig455_057773

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.756

Region-specific R2: 7.016

Region-enriched R2: 7.690/0.00000

1.795 - - - 0.831 - 0.964

Mlig455_036578 {REF} {Length: 1101} {RNA1509_34765} {RNA1310_57079} {RNA815_29388}

Mlig455_057773 {REF} {Length: 629} {RNA1509_34765} {RNA1310_57079, RNA1509_34765} {RNA1509_34765, RNA815_29388}
37. MligTC455_17177 103 2.15 Mlig455_048992, Mlig455_049009

Neo: -

Age: Down-Down-Up

1.794 - - - 0.834 - 0.960

Mlig455_048992 {REF} {Length: 1836} {RNA1509_44702} {RNA1310_14743, RNA1509_44702} {RNA1509_44702, RNA815_20669.1}

Mlig455_049009 {REF} {Length: 1823} {RNA1509_44702} {RNA1310_14743} {RNA815_20669.1}
38. MligTC455_18834 33 0.68 Mlig455_000603

Neo: -

Age: -

1.793 - - - 0.833 - 0.960 Mlig455_000603 {REF} {Length: 1888} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=22.2]} {RNA1310_27913} {RNA815_25050}
39. MligTC455_11701 54 1.12 Mlig455_042837, Mlig455_045855, Mlig455_045871

Neo: -

Age: -

1.791 - - - 0.831 - 0.960

Mlig455_042837 {REF} {Length: 487} {RNA1310_85827} {RNA815_46819}

Mlig455_045855 {REF} {Length: 487} {RNA1310_85827} {RNA815_46819}

Mlig455_045871 {REF} {Length: 487} {RNA1310_85827} {RNA815_46819}
40. MligTC455_12669 49 1.03 Mlig455_020384

Neo: -

Age: -

1.791 - - - - 0.836 0.955 Mlig455_020384 {REF} {Length: 240} {RNA1310_94238}
41. MligTC455_20043 187 3.9 Mlig455_041694

Neo: -

Age: Up-Down-Up

AAR2 1.791 - - - 0.953 0.838 - Mlig455_041694 {REF} {Length: 5108} {TRANSSPLICED} {Pfam: AAR2 protein [PF05282.13, score=146.0]} {Human: ENSG00000131043, AAR2, AAR2 splicing factor homolog, [RH, Score=91.3, Expect=5e-19]} {Mouse: ENSMUSG00000027628, Aar2, AAR2 splicing factor homolog, [RH, Score=91.3, Expect=4e-19]} {Dmel: FBgn0038590, CG12320, [RH, Score=60.8, Expect=2e-09]} {Celegans: WBGene00008639, F10B5.2, Protein AAR2 homolog, [RH, Score=57.4, Expect=2e-08]} {RNA1509_25244} {RNA1310_4799.1} {RNA815_2545}
42. MligTC455_42520 221 4.6 Mlig455_051277

Neo: -

Age: Down-Up-Up

Region-specific R2: 7.331

Region-enriched R2: 7.171/0.00000

Regeneration-downregulated R2: -3.384

Regeneration-depleted R2: -3.384

1.791 - - - 0.831 - 0.960 Mlig455_051277 {REF} {Length: 969} {RNA1310_42329} {RNA815_20649}
43. MligTC455_47851 36 0.76 Mlig455_047832

Neo: -

Age: -

PACRGL 1.791 - - 0.963 0.828 - - Mlig455_047832 {REF} {Length: 1939} {Pfam: Parkin co-regulated protein [PF10274.11, score=119.9]} {Human: ENSG00000163138, PACRGL, parkin coregulated like, [RH, Score=167, Expect=1e-51]} {Mouse: ENSMUSG00000029089, 5730480H06Rik, RIKEN cDNA 5730480H06 gene, [RH, Score=152, Expect=1e-45]} {Dmel: FBgn0034454, CG15120, [Score=62.0, Expect=2e-11]} {RNA1310_58381}
44. MligTC455_17051 22 0.46 Mlig455_042552

Neo: -

Age: -

GRIA4 1.79 - - - 0.830 - 0.960 Mlig455_042552 {REF} {Length: 3307} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.3]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=45.2]; Receptor family ligand binding region [PF01094.30, score=25.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.8]} {Human: ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=139, Expect=2e-33]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=139, Expect=3e-33]} {Dmel: FBgn0038837, CG3822, [Score=142, Expect=2e-34]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=109, Expect=2e-24]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=246, Expect=7e-74]} {RNA1310_33224} {RNA815_17044}
45. MligTC455_17578 447 9.32 Mlig455_010738

Neo: -

Age: Down-Up-Up

Region-specific R2: 8.320

Region-enriched R2: 9.793/0.00000

1.789 - - - 0.830 - 0.959 Mlig455_010738 {REF} {Length: 642} {RNA1509_48297, RNA1509_55742} {RNA1310_84623, RNA1509_48297, RNA1509_55742} {RNA1509_48297, RNA1509_55742, RNA815_45356}
46. MligTC455_27865 53 1.11 Mlig455_035921

Neo: -

Age: -

Regeneration-upregulated R2: 5.914

Regeneration-enriched R2: 5.914

SPRR3 1.789 - - - - 0.833 0.956 Mlig455_035921 {REF} {Length: 1730} {Pfam: Cornifin (SPRR) family [PF02389.17, score=56.6]; Fibrinogen binding protein [PF08017.13, score=18.2]} {Human: ENSG00000163209, SPRR3, small proline rich protein 3, [RH, Score=71.2, Expect=2e-14]} {RNA1509_35339} {RNA1310_43126.1}
47. MligTC455_34503 27 0.57 Mlig455_024885

Neo: -

Age: -

1.789 - - - - 0.830 0.959 Mlig455_024885 {REF} {Length: 1211} {RNA1310_48713} {RNA815_64021}
48. MligTC455_49334 86 1.78 Mlig455_037751

Neo: -

Age: -

1.789 - - - 0.825 - 0.964 Mlig455_037751 {REF} {Length: 708} {RNA1509_25826} {RNA1310_47741} {RNA815_23874}
49. MligTC455_19249 90 1.86 Mlig455_054092

Neo: -

Age: Down-Up-Up

Region-enriched R2: 7.298/0.00139

1.788 - - - 0.837 - 0.951 Mlig455_054092 {REF} {Length: 667} {TRANSSPLICED} {RNA1509_57448} {RNA1310_51394, RNA1509_57448} {RNA1509_57448, RNA815_26076}
50. MligTC455_52629 472 9.83 Mlig455_059435

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.775

Region-enriched R2: 6.727/0.00002

1.787 - - - 0.827 - 0.960 Mlig455_059435 {REF} {Length: 726} {RNA1509_48505} {RNA1310_62885} {RNA815_39881}
51. MligTC455_13435 10 0.21 Mlig455_025954

Neo: -

Age: -

1.786 - - - 0.826 - 0.960 Mlig455_025954 {REF} {Length: 1663} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=35.5]} {RNA1310_51631} {RNA815_34338}
52. MligTC455_26322 65 1.35 Mlig455_042546

Neo: -

Age: -

GRID2 1.786 - - - 0.830 - 0.956 Mlig455_042546 {REF} {Length: 3217} {Pfam: Ligand-gated ion channel [PF00060.28, score=79.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=49.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=35.5]; Receptor family ligand binding region [PF01094.30, score=33.7]} {Human: ENSG00000152208, GRID2, glutamate ionotropic receptor delta type subunit 2, [Score=127, Expect=3e-29]} {Mouse: ENSMUSG00000071424, Grid2, glutamate receptor, ionotropic, delta 2, [Score=129, Expect=5e-30]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=133, Expect=1e-31]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=105, Expect=6e-23]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=238, Expect=8e-71]} {RNA1310_27694} {RNA815_34664}
53. MligTC455_14483 140 2.92 Mlig455_028240

Neo: -

Age: -

Region-enriched R2: 6.203/0.04837

1.785 - - - 0.833 - 0.952 Mlig455_028240 {REF} {Length: 728} {RNA1310_111517} {RNA815_9716}
54. MligTC455_18945 41 0.86 Mlig455_031602

Neo: -

Age: -

1.785 - - - 0.825 - 0.960 Mlig455_031602 {REF} {Length: 914} {RNA1310_75361} {RNA815_24378}
55. MligTC455_19552 288 6 Mlig455_055936, Mlig455_068188

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.424

Region-specific R2: 6.302

Region-enriched R2: 4.919/0.00633

Regeneration-depleted R4: -5.607
Regeneration-depleted R2: -3.270

1.785 - - - 0.835 - 0.950

Mlig455_055936 {REF} {Length: 665} {RNA1310_71052} {RNA815_36745}

Mlig455_068188 {REF} {Length: 714} {RNA1310_71052} {RNA815_36745}
56. MligTC455_19908 490 10.21 Mlig455_047266, Mlig455_047318, Mlig455_069346

Neo: -

Age: logFC(26M/2M)=0.566

1.785 0.822 - - - - 0.963

Mlig455_047266 {REF} {Length: 1728} {Pfam: Glycine rich protein [PF12810.9, score=49.4]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}

Mlig455_047318 {REF} {Length: 2268} {Pfam: Glycine rich protein [PF12810.9, score=36.7]} {RNA1509_28009} {RNA1310_17226, RNA1509_28009} {RNA1509_28009, RNA815_32720}

Mlig455_069346 {REF} {Length: 1953} {Pfam: Glycine rich protein [PF12810.9, score=31.6]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}
57. MligTC455_29412 46 0.96 Mlig455_000627, Mlig455_008268, Mlig455_040614

Neo: -

Age: Up-Down-Up

1.785 - - - 0.831 - 0.954

Mlig455_000627 {REF} {Length: 1331} {RNA1310_62571} {RNA815_30942}

Mlig455_008268 {REF} {Length: 1779} {RNA1509_47298} {RNA1310_98344} {RNA815_10804.1}

Mlig455_040614 {REF} {Length: 1016}
58. MligTC455_12261 66 1.38 Mlig455_013614

Neo: -

Age: -

1.784 0.825 - 0.959 - - - Mlig455_013614 {REF} {Length: 2553} {RNA1310_13989} {RNA815_35164}
59. MligTC455_15329 22 0.47 Mlig455_060498

Neo: -

Age: -

1.784 - - - 0.823 - 0.961 Mlig455_060498 {REF} {Length: 1186} {Pfam: PAN domain [PF00024.28, score=18.9]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=63.9, Expect=4e-12]} {RNA1310_37660} {RNA815_17816.1}
60. MligTC455_43714 152 3.18 Mlig455_000684, Mlig455_000736

Neo: -

Age: -

1.784 - - - 0.825 - 0.959

Mlig455_000684 {REF} {Length: 796} {Pfam: WSC domain [PF01822.21, score=42.8]} {RNA1310_46313} {RNA815_23250}

Mlig455_000736 {REF} {Length: 797} {Pfam: WSC domain [PF01822.21, score=42.8]} {RNA1310_46313} {RNA815_23250}
61. MligTC455_49919 745 15.52 Mlig455_017182, Mlig455_048150

Neo: -

Age: -

Region-specific R2: 7.180

Region-enriched R2: 7.978/0.00000

Regeneration-downregulated R2: -4.649

Regeneration-depleted R2: -4.649

1.782 - - - 0.822 - 0.960

Mlig455_017182 {REF} {Length: 576} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1310_60849, RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1509_35830, RNA1509_49816, RNA1509_53987, RNA815_31347}

Mlig455_048150 {REF} {Length: 574} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830} {RNA1310_60849} {RNA815_31347}
62. MligTC455_18748 104 2.17 Mlig455_024985, Mlig455_024999

Neo: -

Age: -

Region-enriched R2: 6.002/0.00016
Region-enriched R4: 3.433/0.02745

GRIK4 1.781 - - - 0.831 - 0.950

Mlig455_024985 {REF} {Length: 1514} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_47299} {RNA815_38321}

Mlig455_024999 {REF} {Length: 3567} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_7578, RNA1509_35538} {RNA1509_35538, RNA815_4987}
63. MligTC455_50694 602 12.54 Mlig455_058794, Mlig455_070066

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.478

Region-enriched R2: 3.805/0.01454

1.781 - - - 0.819 - 0.962

Mlig455_058794 {REF} {Length: 776} {RNA1310_76208} {RNA815_49041}

Mlig455_070066 {REF} {Length: 781} {RNA1310_76208} {RNA815_49041}
64. MligTC455_25072 4443 92.56 Mlig455_015899

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.175

Region-enriched R2: 4.389/0.00000

PI16 1.779 - - - 0.825 - 0.954 Mlig455_015899 {REF} {Length: 2017} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=71.8]} {Human: ENSG00000164530, PI16, peptidase inhibitor 16, [Score=112, Expect=1e-26]} {Mouse: ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [RH, Score=115, Expect=5e-28]} {Dmel: FBgn0038126, CG8483, [Score=95.5, Expect=2e-21]} {Celegans: WBGene00011462, vap-2, Venom-Allergen-like Protein, [RH, Score=85.5, Expect=5e-18]} {Smed: dd_Smed_v6_2512_0_1, dd_Smed_v6_2512_0_1, [Score=140, Expect=2e-39]} {RNA1509_5027} {RNA1310_1356.1} {RNA815_4508}
65. MligTC455_53546 130 2.72 Mlig455_013326, Mlig455_013334

Neo: -

Age: -

Region-enriched R2: 6.753/0.01892

MMP9 1.779 - - - 0.817 - 0.962

Mlig455_013326 {REF} {Length: 1449} {Pfam: Fibronectin type II domain [PF00040.21, score=92.5]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=87.8, Expect=3e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=82.4, Expect=1e-16]; ENSMUSG00000031740, Mmp2, matrix metallopeptidase 2, [RH, Score=78.6, Expect=2e-15]} {Smed: dd_Smed_v6_14558_0_1, dd_Smed_v6_14558_0_1, [RH, Score=138, Expect=3e-38]} {RNA1310_38631} {RNA815_51136}

Mlig455_013334 {REF} {Length: 1398} {Pfam: Fibronectin type II domain [PF00040.21, score=92.1]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=89.4, Expect=1e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=84.0, Expect=4e-17]} {Smed: dd_Smed_v6_12601_0_1, dd_Smed_v6_12601_0_1, [RH, Score=140, Expect=2e-38]} {RNA1310_38631} {RNA815_51136}
66. MligTC455_30463 95 1.98 Mlig455_000250, Mlig455_058521, Mlig455_058532

Neo: -

Age: -

1.778 - - - 0.805 - 0.973

Mlig455_000250 {REF} {Length: 1994} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=19.7]} {RNA1310_59451} {RNA815_40085}

Mlig455_058521 {REF} {Length: 1237} {RNA1310_56656} {RNA815_40085}

Mlig455_058532 {REF} {Length: 1973} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=19.5]} {RNA1310_59451} {RNA815_40085}
67. MligTC455_50348 34 0.7 Mlig455_012803

Neo: -

Age: -

1.773 - - - 0.804 - 0.969 Mlig455_012803 {REF} {Length: 488} {RNA1509_48155} {RNA1310_70969.2} {RNA815_39712}
68. MligTC455_51334 326 6.78 Mlig455_011442, Mlig455_061180

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.828

1.773 - - - 0.817 - 0.956

Mlig455_011442 {REF} {Length: 742} {RNA1310_57576.1} {RNA815_29867}

Mlig455_061180 {REF} {Length: 769} {RNA1310_57576.1} {RNA815_29867}
69. MligTC455_53839 106 2.21 Mlig455_008195, Mlig455_069578

Neo: -

Age: -

1.773 - - 0.951 0.822 - -

Mlig455_008195 {REF} {Length: 2376} {Smed: dd_Smed_v6_4245_0_1, dd_Smed_v6_4245_0_1, [Score=54.7, Expect=8e-08]} {RNA1310_37888} {RNA815_29107}

Mlig455_069578 {REF} {Length: 2376} {Smed: dd_Smed_v6_4245_0_1, dd_Smed_v6_4245_0_1, [Score=54.7, Expect=8e-08]} {RNA1310_37888} {RNA815_29107}
70. MligTC455_13902 400 8.32 Mlig455_011022, Mlig455_011835, Mlig455_013117

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.562

Region-specific R2: 6.064

Region-enriched R2: 5.080/0.00072

1.771 - - - 0.815 - 0.956

Mlig455_011022 {REF} {Length: 631} {RNA1509_28527} {RNA1310_38436.1} {RNA815_28856}

Mlig455_011835 {REF} {Length: 2387} {RNA1509_28527} {RNA1310_38436.1} {RNA815_28856}

Mlig455_013117 {REF} {Length: 1663} {NoTransDecoderORF} {RNA1310_40518} {RNA815_20411.2}
71. MligTC455_47675 2101 43.77 Mlig455_061675, Mlig455_063136

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.812

Region-specific R2: 4.381

Region-enriched R2: 4.099/0.00000

CLEC18C 1.771 - - - 0.815 - 0.956

Mlig455_061675 {REF} {Length: 2392} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=60.3]} {Human: ENSG00000157335, CLEC18C, C-type lectin domain family 18 member C, [RH, Score=75.5, Expect=1e-13]; ENSG00000140839, CLEC18B, C-type lectin domain family 18 member B, [RH, Score=75.1, Expect=1e-13]} {Mouse: ENSMUSG00000020213, Glipr1l1, GLI pathogenesis-related 1 like 1, [Score=77.8, Expect=1e-15]; ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [Score=75.9, Expect=7e-15]} {Celegans: WBGene00003055, lon-1, LONg, [Score=62.8, Expect=2e-10]} {Smed: dd_Smed_v6_2021_0_1, dd_Smed_v6_2021_0_1, [Score=134, Expect=5e-33]} {RNA1509_48080} {RNA1310_16102.1} {RNA815_9265}

Mlig455_063136 {REF} {Length: 2649} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=60.7]} {Human: ENSG00000157335, CLEC18C, C-type lectin domain family 18 member C, [RH, Score=77.8, Expect=1e-14]; ENSG00000140839, CLEC18B, C-type lectin domain family 18 member B, [RH, Score=77.4, Expect=1e-14]; ENSG00000157322, CLEC18A, C-type lectin domain family 18 member A, [RH, Score=77.0, Expect=2e-14]} {Mouse: ENSMUSG00000020213, Glipr1l1, GLI pathogenesis-related 1 like 1, [Score=78.2, Expect=5e-16]; ENSMUSG00000024011, Pi16, peptidase inhibitor 16, [Score=76.3, Expect=3e-14]} {Celegans: WBGene00003055, lon-1, LONg, [Score=63.5, Expect=6e-11]} {Smed: dd_Smed_v6_2021_0_1, dd_Smed_v6_2021_0_1, [RH, Score=136, Expect=3e-34]} {RNA1509_48080} {RNA1310_16102.1} {RNA815_9265}
72. MligTC455_51009 16 0.33 Mlig455_057754

Neo: -

Age: -

1.771 - - - 0.811 - 0.960 Mlig455_057754 {REF} {Length: 198} {NoTransDecoderORF}
73. MligTC455_49825 543 11.31 Mlig455_069114

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.806

Region-enriched R2: 3.936/0.00000

1.769 - - - 0.816 - 0.953 Mlig455_069114 {REF} {Length: 828} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [Score=40.0, Expect=9e-06]} {RNA1509_26665} {RNA1310_48731, RNA1509_26665} {RNA1509_26665, RNA815_24488}
74. MligTC455_38875 37 0.78 Mlig455_029375, Mlig455_029415

Neo: -

Age: logFC(26M/2M)=-0.939

GRIK2 1.768 - - - 0.814 - 0.954

Mlig455_029375 {REF} {Length: 3713} {Pfam: Ligand-gated ion channel [PF00060.28, score=88.9]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=58.3]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=34.5]; Receptor family ligand binding region [PF01094.30, score=20.4]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=136, Expect=2e-32]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=137, Expect=9e-33]} {Dmel: FBgn0038837, CG3822, [Score=150, Expect=4e-37]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=242, Expect=3e-72]} {RNA1310_67049} {RNA815_49856}

Mlig455_029415 {REF} {Length: 2520} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=25.5]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=73.9, Expect=5e-14]} {RNA1310_74947} {RNA815_49856}
75. MligTC455_45811 216 4.5 Mlig455_015628

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.807/0.00004

1.768 - - - 0.814 - 0.954 Mlig455_015628 {REF} {Length: 1061} {RNA1310_43338} {RNA815_24238}
76. MligTC455_17218 37 0.78 Mlig455_053853

Neo: -

Age: -

1.767 - - - 0.807 - 0.960 Mlig455_053853 {REF} {Length: 1743} {RNA1310_61921}
77. MligTC455_35895 102 2.12 Mlig455_063971

Neo: -

Age: -

RYK 1.767 0.805 - - - - 0.962 Mlig455_063971 {REF} {Length: 3496} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=209.4]; WIF domain [PF02019.20, score=109.7]; Protein kinase domain [PF00069.27, score=79.1]} {Human: ENSG00000163785, RYK, receptor-like tyrosine kinase, [Score=202, Expect=1e-55]} {Mouse: ENSMUSG00000032547, Ryk, receptor-like tyrosine kinase, [RH, Score=202, Expect=2e-55]} {Dmel: FBgn0015380, drl, derailed, [RH, Score=239, Expect=4e-69]} {Celegans: WBGene00003007, lin-18, Inactive tyrosine-protein kinase RYK, [Score=179, Expect=6e-48]} {Smed: dd_Smed_v6_12594_0_2, dd_Smed_v6_12594_0_2, [Score=201, Expect=3e-55]} {RNA1509_58811} {RNA1310_6671.2} {RNA815_41921}
78. MligTC455_27216 56 1.18 Mlig455_022418

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.523

TRPM3 1.766 - - - 0.809 - 0.957 Mlig455_022418 {REF} {Length: 4794} {Pfam: SLOG in TRPM [PF18139.3, score=136.8]; Ion transport protein [PF00520.33, score=41.0]; SLOG in TRPM, prokaryote [PF18171.3, score=34.2]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=317, Expect=2e-88]; ENSG00000119121, TRPM6, transient receptor potential cation channel subfamily M member 6, [Score=316, Expect=4e-88]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=319, Expect=4e-90]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=309, Expect=7e-88]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=255, Expect=4e-69]} {Smed: dd_Smed_v6_9288_0_1, dd_Smed_v6_9288_0_1, [Score=418, Expect=3e-126]} {RNA1509_17593} {RNA1310_1651, RNA1509_17593} {RNA1509_17593, RNA815_2281}
79. MligTC455_35738 32 0.66 Mlig455_043312

Neo: -

Age: -

Region-enriched R4: 7.119/0.01931

ADGRL2 1.765 - - - 0.799 - 0.966 Mlig455_043312 {REF} {Length: 3897} {Pfam: 7 transmembrane receptor (Secretin family) [PF00002.26, score=111.8]; Myc amino-terminal region [PF01056.20, score=20.2]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [RH, Score=138, Expect=2e-33]} {Mouse: ENSMUSG00000028184, Adgrl2, adhesion G protein-coupled receptor L2, [RH, Score=139, Expect=4e-34]; ENSMUSG00000013033, Adgrl1, adhesion G protein-coupled receptor L1, [RH, Score=136, Expect=3e-33]} {Celegans: WBGene00002252, lat-2, Latrophilin-like protein LAT-2, [Score=118, Expect=1e-27]} {Smed: dd_Smed_v6_16446_0_2, dd_Smed_v6_16446_0_2, [Score=199, Expect=4e-55]} {RNA1509_25495} {RNA1310_3070} {RNA815_2153}
80. MligTC455_35802 114 2.38 Mlig455_051876, Mlig455_051902, Mlig455_053140

Neo: -

Age: -

CACNA2D1 1.765 - - - 0.803 - 0.962

Mlig455_051876 {REF} {Length: 3144} {Pfam: Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=89.1]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=84.7, Expect=2e-16]} {RNA1509_55590} {RNA1310_60852} {RNA815_15380}

Mlig455_051902 {REF} {Length: 4662} {Pfam: VWA N-terminal [PF08399.13, score=90.4]; Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=87.6]; von Willebrand factor type A domain [PF00092.30, score=38.6]; Cache domain [PF02743.20, score=27.5]; von Willebrand factor type A domain [PF13519.8, score=26.5]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [RH, Score=326, Expect=8e-94]} {Mouse: ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [RH, Score=326, Expect=7e-94]} {Dmel: FBgn0261041, stj, straightjacket, [Score=229, Expect=7e-61]} {Celegans: WBGene00006772, unc-36, Voltage-dependent calcium channel unc-36, [Score=141, Expect=9e-34]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [Score=153, Expect=1e-37]} {RNA1509_55590} {RNA1310_7325.1, RNA1509_55590} {RNA1509_55590, RNA815_14878}

Mlig455_053140 {REF} {Length: 3265} {Pfam: Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=87.9]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=87.0, Expect=8e-17]} {Mouse: ENSMUSG00000021991, Cacna2d3, calcium channel, voltage-dependent, alpha2/delta subunit 3, [Score=50.4, Expect=9e-06]} {RNA1509_55590} {RNA1310_7325.1} {RNA815_14878}
81. MligTC455_46430 62 1.29 Mlig455_057117, Mlig455_069301

Neo: -

Age: -

GUCY2F 1.765 - - - 0.798 - 0.967

Mlig455_057117 {REF} {Length: 2651} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=196.0]; Nitrate and nitrite sensing [PF08376.12, score=82.5]; Heme NO binding associated [PF07701.16, score=28.2]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=247, Expect=9e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=242, Expect=3e-68]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=238, Expect=5e-67]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=246, Expect=7e-70]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=242, Expect=2e-68]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=241, Expect=7e-68]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=239, Expect=3e-67]} {Dmel: FBgn0053958, CG33958, [Score=266, Expect=4e-79]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=235, Expect=3e-66]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=238, Expect=4e-67]} {RNA1509_38781} {RNA1310_35456} {RNA815_22108}

Mlig455_069301 {REF} {Length: 2370} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=178.1]; Nitrate and nitrite sensing [PF08376.12, score=82.3]; Heme NO binding associated [PF07701.16, score=28.0]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=232, Expect=2e-64]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=232, Expect=1e-64]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=225, Expect=5e-62]} {Dmel: FBgn0053958, CG33958, [Score=250, Expect=5e-73]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=223, Expect=1e-61]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=221, Expect=4e-61]} {RNA1509_38781} {RNA1310_35456} {RNA815_24181}
82. MligTC455_17806 20 0.42 Mlig455_044877

Neo: -

Age: -

1.763 - - - 0.802 - 0.961 Mlig455_044877 {REF} {Length: 1723} {Pfam: F5/8 type C domain [PF00754.27, score=29.9]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [RH, Score=67.8, Expect=2e-14]} {RNA1310_72359} {RNA815_40265}
83. MligTC455_18139 70 1.45 Mlig455_010809

Neo: -

Age: logFC(26M/2M)=-0.809

Region-enriched R2: 6.868/0.00081

TRPC5 1.763 - - - 0.784 - 0.979 Mlig455_010809 {REF} {Length: 4442} {Pfam: Ion transport protein [PF00520.33, score=98.6]; Transient receptor ion channel II [PF08344.13, score=94.3]; Polycystin cation channel [PF08016.14, score=49.0]; Ankyrin repeats (many copies) [PF13637.8, score=37.1]; Ankyrin repeats (3 copies) [PF12796.9, score=33.2]; Ankyrin repeat [PF13606.8, score=25.4]; Ankyrin repeats (many copies) [PF13857.8, score=24.1]; Ankyrin repeat [PF00023.32, score=23.2]} {Human: ENSG00000072315, TRPC5, transient receptor potential cation channel subfamily C member 5, [RH, Score=743, Expect=0.0]; ENSG00000133107, TRPC4, transient receptor potential cation channel subfamily C member 4, [RH, Score=740, Expect=0.0]} {Mouse: ENSMUSG00000041710, Trpc5, transient receptor potential cation channel, subfamily C, member 5, [RH, Score=744, Expect=0.0]; ENSMUSG00000027748, Trpc4, transient receptor potential cation channel, subfamily C, member 4, [RH, Score=740, Expect=0.0]} {Dmel: FBgn0032593, Trpgamma, Transient receptor potential cation channel gamma, [RH, Score=848, Expect=0.0]} {Celegans: WBGene00006615, trp-2, TRP (Transient receptor potential) channel family; TRP homlogous cation channel protein, [RH, Score=694, Expect=0.0]} {Smed: dd_Smed_v6_20495_0_1, dd_Smed_v6_20495_0_1, [RH, Score=1017, Expect=0.0]} {RNA1509_34138} {RNA1310_12839, RNA1509_34138} {RNA1509_34138, RNA815_17637}
84. MligTC455_49824 466 9.71 Mlig455_036536

Neo: -

Age: -

Region-specific R2: 4.841

Region-enriched R2: 3.862/0.00010

1.761 - - - 0.808 - 0.953 Mlig455_036536 {REF} {Length: 1139} {Pfam: Nucleoporin FG repeat region [PF13634.8, score=21.2]} {Celegans: WBGene00003748, nlp-10, Neuropeptide-Like Protein, [RH, Score=49.3, Expect=7e-08]} {RNA1509_18714, RNA1509_59524} {RNA1310_41906, RNA1509_18714, RNA1509_59524} {RNA1509_18714, RNA1509_59524, RNA815_24488}
85. MligTC455_43322 67 1.4 Mlig455_032888

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.946

Region-enriched R2: 7.587/0.00001

1.759 - - - - 0.789 0.970 Mlig455_032888 {REF} {Length: 2179} {RNA1509_40507, RNA1509_49821} {RNA1310_22780, RNA1509_40507} {RNA1509_40507, RNA815_9762}
86. MligTC455_30852 46 0.96 Mlig455_019345, Mlig455_019563, Mlig455_059135

Neo: -

Age: -

GRIA2, GRIK2, GRIK4 1.758 - - - 0.784 - 0.974

Mlig455_019345 {REF} {Length: 3399} {Pfam: Ligand-gated ion channel [PF00060.28, score=95.4]; Receptor family ligand binding region [PF01094.30, score=56.8]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=25.8]; Iron-containing alcohol dehydrogenase [PF13685.8, score=21.9]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=159, Expect=1e-39]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=157, Expect=9e-39]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=159, Expect=7e-40]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=155, Expect=2e-38]} {Dmel: FBgn0039927, CG11155, [Score=160, Expect=3e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [RH, Score=281, Expect=4e-87]} {RNA1509_10728} {RNA1310_122.1} {RNA815_8415.1}

Mlig455_019563 {REF} {Length: 2692} {Pfam: Ligand-gated ion channel [PF00060.28, score=91.5]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=98.6, Expect=6e-23]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=95.9, Expect=5e-22]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=94.7, Expect=1e-21]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=96.7, Expect=2e-22]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=95.9, Expect=3e-22]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=94.7, Expect=9e-22]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=92.8, Expect=4e-21]} {Dmel: FBgn0038837, CG3822, [Score=99.4, Expect=2e-23]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=92.8, Expect=2e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=176, Expect=4e-53]} {RNA1310_21734.1} {RNA815_52393}

Mlig455_059135 {REF} {Length: 3434} {Pfam: Receptor family ligand binding region [PF01094.30, score=58.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=45.1]; Iron-containing alcohol dehydrogenase [PF13685.8, score=23.1]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=71.6, Expect=2e-12]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=70.5, Expect=3e-12]} {Dmel: FBgn0038837, CG3822, [Score=62.0, Expect=1e-09]} {Celegans: WBGene00001617, glr-6, GLutamate Receptor family (AMPA), [Score=68.6, Expect=6e-12]} {Smed: dd_Smed_v6_41723_0_2, dd_Smed_v6_41723_0_2, [Score=85.1, Expect=8e-18]} {RNA1509_10728} {RNA1310_122.1} {RNA815_8415.1}
87. MligTC455_02985 22 0.45 Mlig455_057981

Neo: -

Age: -

1.755 - - - - 0.774 0.981 Mlig455_057981 {REF} {Length: 299} {RNA1509_13251} {RNA1310_4626}
88. MligTC455_23029 200 4.16 Mlig455_043356

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.584/0.02978

ABL1 1.755 - - 0.952 0.803 - - Mlig455_043356 {REF} {Length: 5848} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=320.1]; Protein kinase domain [PF00069.27, score=153.7]; SH2 domain [PF00017.26, score=78.5]; F-actin binding [PF08919.12, score=34.5]; Variant SH3 domain [PF14604.8, score=20.6]; SH3 domain [PF00018.30, score=18.8]} {Human: ENSG00000097007, ABL1, ABL proto-oncogene 1, non-receptor tyrosine kinase, [RH, Score=548, Expect=1e-176]; ENSG00000143322, ABL2, ABL proto-oncogene 2, non-receptor tyrosine kinase, [RH, Score=543, Expect=3e-174]} {Mouse: ENSMUSG00000026842, Abl1, c-abl oncogene 1, non-receptor tyrosine kinase, [RH, Score=549, Expect=2e-177]; ENSMUSG00000026596, Abl2, v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene), [RH, Score=538, Expect=9e-174]} {Dmel: FBgn0000017, Abl, Abl tyrosine kinase, [RH, Score=548, Expect=3e-172]} {Celegans: WBGene00000018, abl-1, Tyrosine-protein kinase abl-1, [RH, Score=517, Expect=2e-164]} {Smed: dd_Smed_v6_4352_0_1, dd_Smed_v6_4352_0_1, [RH, Score=555, Expect=0.0]} {RNA1509_21216, RNA1509_50452} {RNA1310_7858, RNA1509_50452} {RNA1509_50452, RNA815_21818}
89. MligTC455_21210 58 1.21 Mlig455_054815, Mlig455_054824

Neo: -

Age: -

1.753 - - - 0.791 - 0.962

Mlig455_054815 {REF} {Length: 1627} {Celegans: WBGene00044176, C30G7.2, [Score=80.9, Expect=2e-19]} {Smed: dd_Smed_v6_8948_0_1, dd_Smed_v6_8948_0_1, [RH, Score=90.9, Expect=9e-24]} {RNA1509_36146} {RNA1310_58910} {RNA815_43112}

Mlig455_054824 {REF} {Length: 2264} {Celegans: WBGene00044176, C30G7.2, [Score=80.9, Expect=2e-19]} {Smed: dd_Smed_v6_8948_0_1, dd_Smed_v6_8948_0_1, [RH, Score=90.9, Expect=9e-24]} {RNA1509_36146} {RNA1310_58910} {RNA815_43112}
90. MligTC455_34524 155 3.22 Mlig455_021291

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.905

Region-enriched R2: 4.200/0.01842

1.753 - - - 0.803 - 0.950 Mlig455_021291 {REF} {Length: 1478} {NoTransDecoderORF} {RNA1509_56543} {RNA1310_26920, RNA1509_56543} {RNA1509_56543, RNA815_11718}
91. MligTC455_51313 10 0.21 Mlig455_042838, Mlig455_045872

Neo: -

Age: -

1.752 - - - 0.792 - 0.960

Mlig455_042838 {REF} {Length: 1317} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=32.4]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=30.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=27.6]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=104, Expect=4e-25]}

Mlig455_045872 {REF} {Length: 1317} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=32.4]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=30.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=27.6]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=104, Expect=4e-25]}
92. MligTC455_13042 15 0.3 Mlig455_019940, Mlig455_020013

Neo: -

Age: -

1.75 - - - 0.790 - 0.960

Mlig455_019940 {REF} {Length: 1248} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=35.1]} {RNA1310_131593} {RNA815_62907}

Mlig455_020013 {REF} {Length: 1183} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=38.2]} {RNA1310_131593} {RNA815_62907}
93. MligTC455_48756 622 12.96 Mlig455_054772, Mlig455_054799, Mlig455_054893

Neo: -

Age: -

Region-specific R2: 7.873

Region-enriched R2: 9.003/0.00000

1.75 - - - 0.792 - 0.958

Mlig455_054772 {REF} {Length: 716} {RNA1509_41507} {RNA1310_49516} {RNA815_28703}

Mlig455_054799 {REF} {Length: 625} {RNA1509_41507} {RNA1310_49516} {RNA815_28703}

Mlig455_054893 {REF} {Length: 947} {RNA1509_41507} {RNA1310_49516, RNA1509_41507} {RNA1509_41507, RNA815_28703}
94. MligTC455_23417 265 5.53 Mlig455_017673, Mlig455_017693, Mlig455_017744, Mlig455_053766

Neo: -

Age: Down-Up-Down

Region-enriched R8: 3.842/0.01617

SCNN1B, SCNN1G 1.749 - - 0.787 0.962 - -

Mlig455_017673 {REF} {Length: 3361} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=173.7]} {Human: ENSG00000166828, SCNN1G, sodium channel epithelial 1 gamma subunit, [Score=63.2, Expect=1e-09]; ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=62.8, Expect=1e-09]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=58.9, Expect=1e-08]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=52.4, Expect=8e-07]} {Smed: dd_Smed_v6_16274_0_1, dd_Smed_v6_16274_0_1, [Score=407, Expect=4e-134]} {RNA1509_47590} {RNA1310_9831.1} {RNA815_24447}

Mlig455_017693 {REF} {Length: 3484} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=173.7]} {Human: ENSG00000166828, SCNN1G, sodium channel epithelial 1 gamma subunit, [Score=63.2, Expect=1e-09]; ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=62.8, Expect=1e-09]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=58.9, Expect=1e-08]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=52.4, Expect=8e-07]} {Smed: dd_Smed_v6_16274_0_1, dd_Smed_v6_16274_0_1, [Score=407, Expect=4e-134]} {RNA1509_47590} {RNA1310_9831.1} {RNA815_24447}

Mlig455_017744 {REF} {Length: 4057} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=172.2]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=61.2, Expect=5e-09]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=57.8, Expect=4e-08]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=51.2, Expect=3e-06]} {Smed: dd_Smed_v6_16274_0_1, dd_Smed_v6_16274_0_1, [Score=411, Expect=2e-133]} {RNA1509_14736} {RNA1310_9831.1} {RNA815_24447}

Mlig455_053766 {REF} {Length: 3434} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=157.7]} {Human: ENSG00000166828, SCNN1G, sodium channel epithelial 1 gamma subunit, [Score=58.5, Expect=3e-08]; ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=57.8, Expect=5e-08]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=58.2, Expect=2e-08]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=52.8, Expect=6e-07]} {Smed: dd_Smed_v6_16274_0_1, dd_Smed_v6_16274_0_1, [Score=352, Expect=4e-113]} {RNA1509_47590} {RNA1310_43224.1} {RNA815_23822}
95. MligTC455_51955 32 0.67 Mlig455_004175

Neo: -

Age: -

1.749 - - - 0.790 - 0.959 Mlig455_004175 {REF} {Length: 1877} {Pfam: PLAC8 family [PF04749.19, score=63.3]} {Mouse: ENSMUSG00000029322, Plac8, placenta-specific 8, [Score=50.8, Expect=1e-08]} {Smed: dd_Smed_v6_865_0_1, dd_Smed_v6_865_0_1, [Score=90.1, Expect=8e-24]} {RNA1310_65065} {RNA815_32734}
96. MligTC455_03382 210 4.37 Mlig455_057035

Neo: -

Age: -

Region-enriched R2: 3.628/0.00113

PDE1C 1.743 0.770 - - - - 0.973 Mlig455_057035 {REF} {Length: 2458} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=275.1]; 3'5'-cyclic nucleotide phosphodiesterase N-terminal [PF08499.14, score=94.2]} {Human: ENSG00000154678, PDE1C, phosphodiesterase 1C, [RH, Score=546, Expect=0.0]} {Mouse: ENSMUSG00000004347, Pde1c, phosphodiesterase 1C, [RH, Score=546, Expect=0.0]} {Dmel: FBgn0264815, Pde1c, Phosphodiesterase 1c, [RH, Score=538, Expect=0.0]} {Celegans: WBGene00011433, pde-1, Probable 3',5'-cyclic phosphodiesterase pde-1, [RH, Score=482, Expect=2e-164]} {Smed: dd_Smed_v6_11039_0_2, dd_Smed_v6_11039_0_2, [RH, Score=613, Expect=0.0]} {RNA1509_46084} {RNA1310_8143.1} {RNA815_6002}
97. MligTC455_41285 139 2.89 Mlig455_069278

Neo: -

Age: logFC(26M/2M)=-0.469

Region-enriched R8: 4.794/0.00005
Region-enriched R2: 3.899/0.00664

TRPM7 1.743 0.787 - - - - 0.956 Mlig455_069278 {REF} {Length: 4453} {tRNA: Val(CAC),pseudo, score=20.3} {Pfam: SLOG in TRPM [PF18139.3, score=112.9]; Ion transport protein [PF00520.33, score=47.3]; SLOG in TRPM, prokaryote [PF18171.3, score=33.2]} {Human: ENSG00000092439, TRPM7, transient receptor potential cation channel subfamily M member 7, [Score=280, Expect=3e-76]} {Mouse: ENSMUSG00000027365, Trpm7, transient receptor potential cation channel, subfamily M, member 7, [Score=281, Expect=9e-77]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=292, Expect=1e-81]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=165, Expect=7e-41]} {Smed: dd_Smed_v6_9288_0_1, dd_Smed_v6_9288_0_1, [Score=411, Expect=1e-123]} {RNA1509_14642} {RNA1310_2379, RNA1509_14642} {RNA1509_14642, RNA815_1069}
98. MligTC455_50253 44 0.92 Mlig455_031495

Neo: -

Age: -

GABRB2 1.741 - - - 0.776 - 0.965 Mlig455_031495 {REF} {Length: 2129} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=58.3]} {Human: ENSG00000145864, GABRB2, gamma-aminobutyric acid type A receptor beta2 subunit, [Score=71.2, Expect=6e-14]} {Mouse: ENSMUSG00000007653, Gabrb2, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2, [Score=67.8, Expect=1e-12]; ENSMUSG00000029212, Gabrb1, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1, [Score=67.4, Expect=1e-12]} {Dmel: FBgn0024963, GluClalpha, [Score=54.3, Expect=3e-08]} {Celegans: WBGene00001594, glc-4, Glutamate-gated ChLoride channel, [Score=66.6, Expect=2e-12]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=70.1, Expect=9e-14]} {RNA1310_46931} {RNA815_25428}
99. MligTC455_15745 27 0.56 Mlig455_040119, Mlig455_067332

Neo: -

Age: -

ANGPTL2 1.74 - - - 0.780 - 0.960

Mlig455_040119 {REF} {Length: 1066} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=123.8]; PAN domain [PF00024.28, score=20.3]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=102, Expect=5e-24]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=100, Expect=2e-23]; ENSG00000116147, TNR, tenascin R, [Score=100, Expect=2e-23]; ENSG00000120332, TNN, tenascin N, [Score=97.8, Expect=3e-22]} {Mouse: ENSMUSG00000026938, Fcna, ficolin A, [Score=102, Expect=8e-25]; ENSMUSG00000015829, Tnr, tenascin R, [Score=101, Expect=1e-23]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=100, Expect=8e-24]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=100, Expect=1e-23]} {Dmel: FBgn0050280, CG30280, [Score=104, Expect=2e-26]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=105, Expect=2e-25]} {RNA1509_58115} {RNA1310_32877} {RNA815_17241}

Mlig455_067332 {REF} {Length: 1104} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=125.5]; PAN domain [PF00024.28, score=19.2]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=104, Expect=1e-24]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=103, Expect=3e-24]; ENSG00000116147, TNR, tenascin R, [Score=101, Expect=2e-23]} {Mouse: ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=103, Expect=2e-24]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=103, Expect=1e-24]; ENSMUSG00000026938, Fcna, ficolin A, [Score=102, Expect=7e-25]; ENSMUSG00000015829, Tnr, tenascin R, [Score=101, Expect=1e-23]} {Dmel: FBgn0050280, CG30280, [Score=107, Expect=2e-27]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=107, Expect=4e-26]} {RNA1509_58115} {RNA1310_32877} {RNA815_17241}
100. MligTC455_25410 47 0.97 Mlig455_026185

Neo: -

Age: Up-Down-Down

Region-enriched R2: 8.036/0.00469
Region-enriched R6: 6.422/0.01487

1.738 - - - - 0.786 0.952 Mlig455_026185 {REF} {Length: 3002} {Pfam: Variant SH3 domain [PF07653.19, score=19.6]; Growth-arrest specific micro-tubule binding [PF13851.8, score=19.3]} {Mouse: ENSMUSG00000034156, Tspoap1, TSPO associated protein 1, [Score=54.7, Expect=6e-07]} {Smed: dd_Smed_v6_14584_0_1, dd_Smed_v6_14584_0_1, [Score=140, Expect=7e-35]} {RNA1509_45271} {RNA1310_5741} {RNA815_46868}

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