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Results for MligTC455_38875

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_38875 37 0.78 Mlig455_029375, Mlig455_029415

Neo: -

Age: logFC(26M/2M)=-0.939

 GRIK2

Mlig455_029375 {REF} {Length: 3713} {Pfam: Ligand-gated ion channel [PF00060.28, score=88.9]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=58.3]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=34.5]; Receptor family ligand binding region [PF01094.30, score=20.4]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=136, Expect=2e-32]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=137, Expect=9e-33]} {Dmel: FBgn0038837, CG3822, [Score=150, Expect=4e-37]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=242, Expect=3e-72]} {RNA1310_67049} {RNA815_49856}

Mlig455_029415 {REF} {Length: 2520} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=25.5]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=73.9, Expect=5e-14]} {RNA1310_74947} {RNA815_49856}

Cumulative graph for MligTC455_38875

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 7.279 1.152 0.99995 1.00000
RegionR2 1.259 1.152 0.97462 1.00000
RegionR3 -2.655 1.152 0.99990 1.00000
RegionR4 3.931 1.152 0.99985 1.00000
RegionR5 -1.607 1.152 0.99988 1.00000
RegionR6 -2.936 1.152 0.99983 1.00000
RegionR7 -2.675 1.152 0.99984 1.00000
RegionR8 -2.596 1.152 0.99984 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -5.984 1.152 0.99996 1.00000
RegenerationR2 1.326 1.152 0.09068 0.48161
RegenerationR3 -1.89 1.152 0.99984 1.00000
RegenerationR4 -2.107 1.152 0.98920 1.00000
RegenerationR5 1.253 1.152 0.87515 1.00000
RegenerationR6 2.026 1.152 0.51141 0.81440
RegenerationBL 4.95 1.152 0.03037 0.19445
RegenerationTP 0.887 1.152 0.95976 1.00000


Genes with expression patterns similar to MligTC455_38875

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_38875 37 0.78 Mlig455_029375, Mlig455_029415

Neo: -

Age: logFC(26M/2M)=-0.939

 GRIK2 5 1.000 - 1.000 1.000 1.000 1.000

Mlig455_029375 {REF} {Length: 3713} {Pfam: Ligand-gated ion channel [PF00060.28, score=88.9]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=58.3]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=34.5]; Receptor family ligand binding region [PF01094.30, score=20.4]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=136, Expect=2e-32]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=137, Expect=9e-33]} {Dmel: FBgn0038837, CG3822, [Score=150, Expect=4e-37]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=242, Expect=3e-72]} {RNA1310_67049} {RNA815_49856}

Mlig455_029415 {REF} {Length: 2520} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=25.5]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=73.9, Expect=5e-14]} {RNA1310_74947} {RNA815_49856}
2. MligTC455_45021 381 7.95 Mlig455_046686

Neo: -

Age: Down-Up-Up

Region-enriched R2: 3.428/0.03156

 AVP 4.568 0.981 - 0.918 0.951 0.747 0.971 Mlig455_046686 {REF} {Length: 1388} {Pfam: Neurohypophysial hormones, C-terminal Domain [PF00184.19, score=36.2]} {Human: ENSG00000101200, AVP, arginine vasopressin, [Score=54.3, Expect=2e-09]} {Mouse: ENSMUSG00000037727, Avp, arginine vasopressin, [Score=53.1, Expect=3e-09]} {RNA1509_50574} {RNA1310_38922} {RNA815_23813}
3. MligTC455_15112 80 1.67 Mlig455_038148

Neo: -

Age: -

Region-enriched R2: 4.134/0.00646
Region-enriched R7: 3.497/0.03308

 4.531 0.986 - 0.814 0.899 0.874 0.958 Mlig455_038148 {REF} {Length: 836}
4. MligTC455_49434 157 3.26 Mlig455_068252, Mlig455_068272

Neo: -

Age: -

 4.28 0.893 - 0.941 0.788 0.702 0.956

Mlig455_068252 {REF} {Length: 718} {Smed: dd_Smed_v6_17523_0_1, dd_Smed_v6_17523_0_1, [Score=63.5, Expect=1e-12]} {RNA1310_75052}

Mlig455_068272 {REF} {Length: 1055} {Smed: dd_Smed_v6_17523_0_1, dd_Smed_v6_17523_0_1, [Score=63.2, Expect=2e-12]} {RNA1310_75052}
5. MligTC455_43072 81 1.68 Mlig455_042521

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.590/0.02161

 3.908 0.994 - 0.935 0.984 - 0.995 Mlig455_042521 {REF} {Length: 1049} {RNA1509_46101} {RNA1310_32444} {RNA815_30668}
6. MligTC455_47712 80 1.66 Mlig455_044833

Neo: -

Age: -

 3.866 0.934 - 0.988 0.965 - 0.979 Mlig455_044833 {REF} {Length: 564} {RNA1509_55855} {RNA1310_87612} {RNA815_50831}
7. MligTC455_16610 98 2.05 Mlig455_069894

Neo: -

Age: -

Region-enriched R2: 5.254/0.03136

 WSCD2 3.864 0.993 - 0.932 0.945 - 0.994 Mlig455_069894 {REF} {Length: 827} {Pfam: WSC domain [PF01822.21, score=59.2]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=55.1, Expect=4e-09]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=47.8, Expect=9e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=52.4, Expect=2e-08]} {RNA1509_46267} {RNA1310_46146} {RNA815_32275.1}
8. MligTC455_19708 304 6.32 Mlig455_009784

Neo: -

Age: -

Region-enriched R2: 6.355/0.00039

 3.855 0.936 - 0.963 0.962 - 0.994 Mlig455_009784 {REF} {Length: 826} {Pfam: Pancreatic hormone peptide [PF00159.20, score=43.3]} {RNA1509_54211} {RNA1310_54505.1, RNA1509_54211} {RNA1509_54211, RNA815_29389}
9. MligTC455_17579 76 1.58 Mlig455_042836, Mlig455_045854, Mlig455_045870

Neo: -

Age: -

 RNF217 3.705 - - 0.945 0.982 0.907 0.871

Mlig455_042836 {REF} {Length: 3004} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=75.3]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=83.6, Expect=5e-16]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=83.2, Expect=4e-16]} {Dmel: FBgn0036082, CG12362, [Score=57.0, Expect=4e-08]} {Celegans: WBGene00020462, T12E12.1, Potential E3 ubiquitin-protein ligase ariadne-2, [Score=57.0, Expect=4e-08]} {Smed: dd_Smed_v6_7986_0_1, dd_Smed_v6_7986_0_1, [Score=61.2, Expect=1e-09]} {RNA1310_42946} {RNA815_24345}

Mlig455_045854 {REF} {Length: 3004} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=74.7]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=83.2, Expect=5e-16]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=83.2, Expect=4e-16]} {Dmel: FBgn0036082, CG12362, [Score=57.4, Expect=3e-08]} {Celegans: WBGene00020462, T12E12.1, Potential E3 ubiquitin-protein ligase ariadne-2, [Score=57.8, Expect=2e-08]} {Smed: dd_Smed_v6_7986_0_1, dd_Smed_v6_7986_0_1, [Score=61.2, Expect=1e-09]} {RNA1310_42946} {RNA815_24345}

Mlig455_045870 {REF} {Length: 3004} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=74.9]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=83.2, Expect=5e-16]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=83.2, Expect=4e-16]} {Dmel: FBgn0036082, CG12362, [Score=57.4, Expect=3e-08]} {Celegans: WBGene00020462, T12E12.1, Potential E3 ubiquitin-protein ligase ariadne-2, [Score=57.0, Expect=4e-08]} {Smed: dd_Smed_v6_7986_0_1, dd_Smed_v6_7986_0_1, [Score=61.2, Expect=1e-09]} {RNA1310_42946} {RNA815_24345}
10. MligTC455_46229 215 4.48 Mlig455_022523, Mlig455_022563

Neo: -

Age: -

Region-enriched R2: 5.024/0.00529

 3.693 - - 0.832 0.978 0.947 0.936

Mlig455_022523 {REF} {Length: 2044} {RNA1310_42787} {RNA815_17352}

Mlig455_022563 {REF} {Length: 1991} {RNA1310_42787} {RNA815_17352}
11. MligTC455_05098 127 2.65 Mlig455_009525, Mlig455_009531

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.095/0.01821

 KCNH7 3.672 0.997 - 0.943 0.870 - 0.862

Mlig455_009525 {REF} {Length: 2109} {Pfam: Ion transport protein [PF00520.33, score=111.8]; Ion channel [PF07885.18, score=46.1]; Cyclic nucleotide-binding domain [PF00027.31, score=36.3]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=29.8]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=528, Expect=4e-176]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=509, Expect=2e-170]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=505, Expect=9e-167]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=527, Expect=4e-175]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=510, Expect=3e-171]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=504, Expect=9e-167]} {Dmel: FBgn0003353, sei, seizure, [Score=507, Expect=2e-171]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=496, Expect=1e-169]} {Smed: dd_Smed_v6_12978_0_1, dd_Smed_v6_12978_0_1, [Score=608, Expect=0.0]} {RNA1509_56964} {RNA1310_41939} {RNA815_5858.1}

Mlig455_009531 {REF} {Length: 3631} {Pfam: Ion transport protein [PF00520.33, score=110.4]; Ion channel [PF07885.18, score=45.2]; Cyclic nucleotide-binding domain [PF00027.31, score=43.3]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=619, Expect=0.0]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=597, Expect=0.0]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=596, Expect=0.0]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=617, Expect=0.0]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=602, Expect=0.0]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=596, Expect=0.0]} {Dmel: FBgn0003353, sei, seizure, [Score=591, Expect=0.0]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=579, Expect=0.0]} {Smed: dd_Smed_v6_12978_0_4, dd_Smed_v6_12978_0_4, [RH, Score=716, Expect=0.0]} {RNA1509_56964} {RNA1310_23186, RNA1509_56964} {RNA1509_56964, RNA815_5858.2}
12. MligTC455_45351 241 5.02 Mlig455_031191

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.622/0.00310

 3.667 - - 0.984 0.989 0.744 0.950 Mlig455_031191 {REF} {Length: 2855} {Pfam: Srg family chemoreceptor [PF02118.23, score=28.1]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=26.4]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=26.4]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=49.3, Expect=2e-06]} {Smed: dd_Smed_v6_7534_0_1, dd_Smed_v6_7534_0_1, [Score=54.7, Expect=4e-08]} {RNA1509_20184} {RNA1310_32455} {RNA815_38062}
13. MligTC455_52629 472 9.83 Mlig455_059435

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.775

Region-enriched R2: 6.727/0.00002

 3.666 - - 0.966 0.995 0.707 0.998 Mlig455_059435 {REF} {Length: 726} {RNA1509_48505} {RNA1310_62885} {RNA815_39881}
14. MligTC455_43173 392 8.16 Mlig455_037383

Neo: -

Age: Up-Down-Down

Regeneration-downregulated TP: -5.031

Regeneration-depleted TP: -5.031

 C2orf16 3.642 0.759 - 0.945 0.957 - 0.981 Mlig455_037383 {REF} {Length: 2450} {Pfam: Cornifin (SPRR) family [PF02389.17, score=23.4]} {Human: ENSG00000221843, C2orf16, chromosome 2 open reading frame 16, [Score=80.1, Expect=7e-15]} {RNA1509_52401} {RNA1310_14622.1} {RNA815_17994}
15. MligTC455_12183 53 1.11 Mlig455_004166, Mlig455_004190

Neo: -

Age: -

Region-enriched R2: 4.930/0.01881

 3.614 - - 0.958 0.985 0.712 0.959

Mlig455_004166 {REF} {Length: 2818} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=57.4]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=29.1]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=55.5, Expect=1e-08]} {Smed: dd_Smed_v6_70862_0_1, dd_Smed_v6_70862_0_1, [Score=60.8, Expect=8e-12]} {RNA1310_64973} {RNA815_58453}

Mlig455_004190 {REF} {Length: 2742} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=56.7]; Serpentine type 7TM GPCR chemoreceptor Srbc [PF10316.11, score=28.6]} {Celegans: WBGene00019019, frpr-10, FMRFamide Peptide Receptor family, [Score=56.2, Expect=1e-08]} {Smed: dd_Smed_v6_70862_0_1, dd_Smed_v6_70862_0_1, [Score=60.8, Expect=1e-11]} {RNA1310_62602} {RNA815_58453}
16. MligTC455_19552 288 6 Mlig455_055936, Mlig455_068188

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.424

Region-specific R2: 6.302

Region-enriched R2: 4.919/0.00633

Regeneration-depleted R4: -5.607
Regeneration-depleted R2: -3.270

 3.608 - - 0.920 0.992 0.701 0.995

Mlig455_055936 {REF} {Length: 665} {RNA1310_71052} {RNA815_36745}

Mlig455_068188 {REF} {Length: 714} {RNA1310_71052} {RNA815_36745}
17. MligTC455_44020 185 3.86 Mlig455_010276

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.370/0.00096

 3.58 0.967 - 0.900 0.800 - 0.913 Mlig455_010276 {REF} {Length: 864} {Pfam: Heat shock factor binding protein 1 [PF06825.14, score=31.1]; Baculovirus polyhedron envelope protein, PEP, C terminus [PF04513.14, score=19.8]; Uncharacterised protein family (UPF0184) [PF03670.15, score=19.0]} {RNA1310_71172} {RNA815_36466}
18. MligTC455_10299 72 1.51 Mlig455_023028, Mlig455_023125, Mlig455_023183

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.617

Region-enriched R2: 4.572/0.04281

 ANGPTL1 3.567 - - 0.981 0.976 0.760 0.850

Mlig455_023028 {REF} {Length: 2538} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=130.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=115, Expect=8e-29]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=112, Expect=1e-27]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=114, Expect=2e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=112, Expect=9e-28]} {Dmel: FBgn0050280, CG30280, [Score=103, Expect=9e-26]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=50.8, Expect=4e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}

Mlig455_023125 {REF} {Length: 2398} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=127.5]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=112, Expect=2e-27]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=107, Expect=1e-25]} {Mouse: ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=107, Expect=7e-26]} {Dmel: FBgn0050280, CG30280, [Score=92.8, Expect=6e-22]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=51.2, Expect=3e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}

Mlig455_023183 {REF} {Length: 2190} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=129.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=115, Expect=2e-28]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=110, Expect=9e-27]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=113, Expect=4e-28]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=110, Expect=6e-27]} {Dmel: FBgn0003326, sca, scabrous, [Score=104, Expect=8e-25]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=50.4, Expect=4e-08]} {RNA1509_41017} {RNA1310_41391} {RNA815_23568}
19. MligTC455_51334 326 6.78 Mlig455_011442, Mlig455_061180

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.828

 3.544 - - 0.844 0.992 0.711 0.997

Mlig455_011442 {REF} {Length: 742} {RNA1310_57576.1} {RNA815_29867}

Mlig455_061180 {REF} {Length: 769} {RNA1310_57576.1} {RNA815_29867}
20. MligTC455_49919 745 15.52 Mlig455_017182, Mlig455_048150

Neo: -

Age: -

Region-specific R2: 7.180

Region-enriched R2: 7.978/0.00000

Regeneration-downregulated R2: -4.649

Regeneration-depleted R2: -4.649

 3.538 - - 0.827 0.990 0.724 0.997

Mlig455_017182 {REF} {Length: 576} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1310_60849, RNA1509_35830, RNA1509_49816, RNA1509_53987} {RNA1509_35830, RNA1509_49816, RNA1509_53987, RNA815_31347}

Mlig455_048150 {REF} {Length: 574} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=24.2]} {RNA1509_35830} {RNA1310_60849} {RNA815_31347}
21. MligTC455_12512 80 1.68 Mlig455_017689

Neo: -

Age: -

 3.534 - - 0.960 0.866 0.714 0.994 Mlig455_017689 {REF} {Length: 934} {RNA1310_37507} {RNA815_32171}
22. MligTC455_47420 218 4.54 Mlig455_017159, Mlig455_048110

Neo: -

Age: -

Region-specific R2: 6.469

Region-enriched R2: 5.851/0.00135

 3.532 - - 0.892 0.988 0.707 0.945

Mlig455_017159 {REF} {Length: 1062} {RNA1509_35349} {RNA1310_81586}

Mlig455_048110 {REF} {Length: 527} {RNA1310_81586}
23. MligTC455_41035 366 7.62 Mlig455_000866

Neo: -

Age: logFC(26M/2M)=-0.773

Region-specific R2: 5.029

Region-enriched R2: 4.768/0.00000

 3.509 0.720 - 0.820 0.977 - 0.992 Mlig455_000866 {REF} {Length: 1126} {Pfam: Pancreatic hormone peptide [PF00159.20, score=41.6]} {RNA1509_27581} {RNA1310_74103, RNA1509_27581} {RNA1509_27581, RNA815_38377}
24. MligTC455_29168 95 1.99 Mlig455_001005

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.838/0.04040

 DNAH5 3.506 0.987 - 0.849 - 0.788 0.882 Mlig455_001005 {REF} {Length: 14882} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=578.4]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=466.5]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=431.3]; Dynein heavy chain C-terminal domain [PF18199.3, score=314.7]; P-loop containing dynein motor region D4 [PF12780.9, score=302.4]; ATP-binding dynein motor region [PF12781.9, score=290.8]; P-loop containing dynein motor region [PF12775.9, score=229.7]; Dynein heavy chain AAA lid domain [PF18198.3, score=179.1]; Microtubule-binding stalk of dynein motor [PF12777.9, score=143.2]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=121.5]; AAA domain (dynein-related subfamily) [PF07728.16, score=75.6]; Dynein heavy chain AAA lid domain [PF17852.3, score=70.7]; AAA+ lid domain [PF17857.3, score=60.9]; AAA ATPase domain [PF13191.8, score=22.0]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=21.4]; P-loop containing region of AAA domain [PF13555.8, score=20.3]} {Human: ENSG00000039139, DNAH5, dynein axonemal heavy chain 5, [RH, Score=6260, Expect=0.0]} {Mouse: ENSMUSG00000022262, Dnah5, dynein, axonemal, heavy chain 5, [RH, Score=6234, Expect=0.0]} {Dmel: FBgn0037726, CG9492, [RH, Score=5093, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=1290, Expect=0.0]} {Smed: dd_Smed_v6_4569_0_1, dd_Smed_v6_4569_0_1, [RH, Score=6941, Expect=0.0]} {RNA1509_51275} {RNA1310_408, RNA1509_51275} {RNA1509_51275, RNA815_44.1}
25. MligTC455_41910 46 0.96 Mlig455_031932, Mlig455_032665, Mlig455_070395

Neo: -

Age: -

 3.502 - - 0.800 0.970 0.918 0.814

Mlig455_031932 {REF} {Length: 811} {Pfam: PAN-like domain [PF08277.14, score=21.2]; Carbohydrate binding domain (family 19) [PF03427.15, score=18.8]} {RNA1310_52317.2} {RNA815_34259}

Mlig455_032665 {REF} {Length: 903} {Pfam: Carbohydrate binding domain (family 19) [PF03427.15, score=21.5]} {RNA1310_52317.1} {RNA815_34259}

Mlig455_070395 {REF} {Length: 636} {Pfam: Carbohydrate binding domain (family 19) [PF03427.15, score=21.5]} {RNA1310_52317.1} {RNA815_34259}
26. MligTC455_38162 710 14.8 Mlig455_045004

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.269

Region-enriched R2: 5.838/0.00000

Regeneration-downregulated R2: -4.412

Regeneration-depleted R2: -4.412

 3.498 - - 0.811 0.964 0.729 0.994 Mlig455_045004 {REF} {Length: 659} {Smed: dd_Smed_v6_4046_0_1, dd_Smed_v6_4046_0_1, [Score=57.8, Expect=2e-12]} {RNA1509_50998, RNA1509_57106} {RNA1310_56015, RNA1509_50998, RNA1509_57106} {RNA1509_50998, RNA1509_57106, RNA815_29915}
27. MligTC455_46452 134 2.79 Mlig455_048151

Neo: -

Age: -

Region-specific R2: 6.389

Region-enriched R2: 7.075/0.00014

Regeneration-downregulated R2: -3.162

Regeneration-depleted R2: -3.162

 3.462 0.811 - 0.712 0.991 - 0.948 Mlig455_048151 {REF} {Length: 618} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=25.7]} {RNA1310_62963} {RNA815_31352}
28. MligTC455_12102 59 1.23 Mlig455_041538, Mlig455_053099

Neo: -

Age: -

Region-enriched R2: 6.626/0.00371

 DEGS2 3.429 - - 0.738 0.858 0.851 0.982

Mlig455_041538 {REF} {Length: 1966} {Pfam: Fatty acid desaturase [PF00487.26, score=87.9]; Sphingolipid Delta4-desaturase (DES) [PF08557.12, score=57.6]} {Human: ENSG00000168350, DEGS2, delta 4-desaturase, sphingolipid 2, [Score=319, Expect=2e-107]; ENSG00000143753, DEGS1, delta 4-desaturase, sphingolipid 1, [Score=315, Expect=5e-106]} {Mouse: ENSMUSG00000038633, Degs1, delta(4)-desaturase, sphingolipid 1, [Score=308, Expect=2e-103]; ENSMUSG00000021263, Degs2, delta(4)-desaturase, sphingolipid 2, [Score=307, Expect=6e-103]} {Dmel: FBgn0001941, ifc, infertile crescent, [Score=345, Expect=5e-118]} {Celegans: WBGene00017996, F33D4.4, Putative sphingolipid delta(4)-desaturase, [Score=318, Expect=4e-107]} {Smed: dd_Smed_v6_7414_0_1, dd_Smed_v6_7414_0_1, [RH, Score=409, Expect=7e-143]} {RNA1310_20672.2} {RNA815_19986}

Mlig455_053099 {REF} {Length: 2009} {Pfam: Fatty acid desaturase [PF00487.26, score=87.9]; Sphingolipid Delta4-desaturase (DES) [PF08557.12, score=57.5]} {Human: ENSG00000168350, DEGS2, delta 4-desaturase, sphingolipid 2, [Score=319, Expect=2e-107]; ENSG00000143753, DEGS1, delta 4-desaturase, sphingolipid 1, [Score=315, Expect=4e-106]} {Mouse: ENSMUSG00000038633, Degs1, delta(4)-desaturase, sphingolipid 1, [Score=309, Expect=7e-104]; ENSMUSG00000021263, Degs2, delta(4)-desaturase, sphingolipid 2, [Score=307, Expect=5e-103]} {Dmel: FBgn0001941, ifc, infertile crescent, [Score=345, Expect=4e-118]} {Celegans: WBGene00017996, F33D4.4, Putative sphingolipid delta(4)-desaturase, [Score=318, Expect=3e-107]} {Smed: dd_Smed_v6_7414_0_1, dd_Smed_v6_7414_0_1, [RH, Score=409, Expect=4e-143]} {RNA1310_20672.1} {RNA815_19986}
29. MligTC455_17299 538 11.21 Mlig455_036559, Mlig455_057787

Neo: -

Age: -

Region-enriched R2: 5.046/0.00000
Region-enriched R3: 3.527/0.00004

 3.382 - - 0.772 0.888 0.732 0.990

Mlig455_036559 {REF} {Length: 718} {RNA1509_57277} {RNA1310_52579, RNA1509_57277} {RNA1509_57277, RNA815_26706}

Mlig455_057787 {REF} {Length: 741} {RNA1509_57277} {RNA1310_52579} {RNA815_26706}
30. MligTC455_48714 132 2.74 Mlig455_037041

Neo: -

Age: -

Region-enriched R2: 4.531/0.00493

 3.363 - - 0.959 0.847 0.770 0.787 Mlig455_037041 {REF} {Length: 1099} {RNA1509_35038} {RNA1310_72135} {RNA815_37404}
31. MligTC455_48490 40 0.84 Mlig455_020090

Neo: -

Age: -

 3.356 - - 0.816 0.830 0.747 0.963 Mlig455_020090 {REF} {Length: 2619} {RNA1310_71062} {RNA815_63441}
32. MligTC455_16358 1175 24.47 Mlig455_039878

Neo: -

Age: -

Region-specific R2: 4.659

Region-enriched R2: 4.310/0.00000

 3.329 - - 0.814 0.985 0.746 0.784 Mlig455_039878 {REF} {Length: 1188} {RNA1509_60020} {RNA1310_35099.1, RNA1509_60020} {RNA1509_60020, RNA815_1356.1}
33. MligTC455_53435 190 3.96 Mlig455_045425, Mlig455_065748

Neo: -

Age: -

Region-enriched R2: 4.111/0.00023

 SYT9 3.156 - - 0.732 0.746 0.712 0.966

Mlig455_045425 {REF} {Length: 2615} {RNA1509_46689} {RNA1310_15031, RNA1509_46689} {RNA1509_46689, RNA815_18779.1}

Mlig455_065748 {REF} {Length: 3143} {Pfam: C2 domain [PF00168.32, score=116.1]} {Human: ENSG00000170743, SYT9, synaptotagmin 9, [Score=162, Expect=4e-42]; ENSG00000213023, SYT3, synaptotagmin 3, [Score=157, Expect=5e-40]} {Mouse: ENSMUSG00000062542, Syt9, synaptotagmin IX, [Score=162, Expect=3e-42]; ENSMUSG00000030731, Syt3, synaptotagmin III, [Score=156, Expect=1e-39]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [RH, Score=197, Expect=1e-54]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=144, Expect=8e-37]} {Smed: dd_Smed_v6_6730_0_1, dd_Smed_v6_6730_0_1, [Score=155, Expect=5e-41]} {RNA1509_46689} {RNA1310_15031} {RNA815_18779.1}
34. MligTC455_43714 152 3.18 Mlig455_000684, Mlig455_000736

Neo: -

Age: -

 2.989 - - 0.996 0.995 - 0.998

Mlig455_000684 {REF} {Length: 796} {Pfam: WSC domain [PF01822.21, score=42.8]} {RNA1310_46313} {RNA815_23250}

Mlig455_000736 {REF} {Length: 797} {Pfam: WSC domain [PF01822.21, score=42.8]} {RNA1310_46313} {RNA815_23250}
35. MligTC455_37793 353 7.36 Mlig455_066109, Mlig455_068663

Neo: -

Age: Up-Down-Down

 HMCN1 2.988 0.996 - 0.997 - - 0.995

Mlig455_066109 {REF} {Length: 7924} {Pfam: Thrombospondin type 1 domain [PF00090.21, score=408.1]; Spondin-like TSP1 domain [PF19028.2, score=285.5]; Polycystin cation channel [PF08016.14, score=239.7]; PLAT/LH2 domain [PF01477.25, score=86.7]; Thrombospondin type 1 domain [PF19030.2, score=78.4]; Ion transport protein [PF00520.33, score=42.7]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=360, Expect=8e-99]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=363, Expect=7e-100]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [Score=199, Expect=5e-51]} {Celegans: WBGene00000082, adt-1, ADAMTS family; ADT-1, [RH, Score=306, Expect=4e-84]} {Smed: dd_Smed_v6_13975_0_1, dd_Smed_v6_13975_0_1, [RH, Score=944, Expect=0.0]} {RNA1509_9601} {RNA1310_488} {RNA815_1711}

Mlig455_068663 {REF} {Length: 7866} {Pfam: Thrombospondin type 1 domain [PF00090.21, score=423.7]; Spondin-like TSP1 domain [PF19028.2, score=299.7]; Thrombospondin type 1 domain [PF19030.2, score=92.3]; PLAT/LH2 domain [PF01477.25, score=23.1]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=338, Expect=1e-94]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=341, Expect=9e-96]} {Dmel: FBgn0284221, Sema5c, Semaphorin 5c, [Score=189, Expect=2e-48]} {Celegans: WBGene00000082, adt-1, ADAMTS family; ADT-1, [RH, Score=303, Expect=2e-84]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=282, Expect=3e-77]} {RNA1509_9601} {RNA1310_488} {RNA815_1711}
36. MligTC455_17578 447 9.32 Mlig455_010738

Neo: -

Age: Down-Up-Up

Region-specific R2: 8.320

Region-enriched R2: 9.793/0.00000

 2.984 - - 0.994 0.997 - 0.993 Mlig455_010738 {REF} {Length: 642} {RNA1509_48297, RNA1509_55742} {RNA1310_84623, RNA1509_48297, RNA1509_55742} {RNA1509_48297, RNA1509_55742, RNA815_45356}
37. MligTC455_19235 18 0.38 Mlig455_013768

Neo: -

Age: -

 2.982 - - 0.999 0.989 - 0.994 Mlig455_013768 {REF} {Length: 2312} {Pfam: Glycine rich protein [PF12810.9, score=36.9]; PAN domain [PF00024.28, score=24.7]} {RNA1310_126710} {RNA815_35307}
38. MligTC455_18945 41 0.86 Mlig455_031602

Neo: -

Age: -

 2.971 - - 0.978 0.995 - 0.998 Mlig455_031602 {REF} {Length: 914} {RNA1310_75361} {RNA815_24378}
39. MligTC455_51313 10 0.21 Mlig455_042838, Mlig455_045872

Neo: -

Age: -

 2.971 - - 0.993 0.980 - 0.998

Mlig455_042838 {REF} {Length: 1317} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=32.4]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=30.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=27.6]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=104, Expect=4e-25]}

Mlig455_045872 {REF} {Length: 1317} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=32.4]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=30.6]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=27.6]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=104, Expect=4e-25]}
40. MligTC455_13435 10 0.21 Mlig455_025954

Neo: -

Age: -

 2.966 - - 0.998 0.970 - 0.998 Mlig455_025954 {REF} {Length: 1663} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=35.5]} {RNA1310_51631} {RNA815_34338}
41. MligTC455_51955 32 0.67 Mlig455_004175

Neo: -

Age: -

 2.961 - - 0.999 0.964 - 0.998 Mlig455_004175 {REF} {Length: 1877} {Pfam: PLAC8 family [PF04749.19, score=63.3]} {Mouse: ENSMUSG00000029322, Plac8, placenta-specific 8, [Score=50.8, Expect=1e-08]} {Smed: dd_Smed_v6_865_0_1, dd_Smed_v6_865_0_1, [Score=90.1, Expect=8e-24]} {RNA1310_65065} {RNA815_32734}
42. MligTC455_10567 11 0.23 Mlig455_012840

Neo: -

Age: -

 TNN 2.954 - - 0.998 0.958 - 0.998 Mlig455_012840 {REF} {Length: 1231} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=140.5]; PAN domain [PF00024.28, score=19.1]} {Human: ENSG00000120332, TNN, tenascin N, [Score=104, Expect=2e-24]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=103, Expect=3e-25]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=103, Expect=3e-24]; ENSG00000116147, TNR, tenascin R, [Score=101, Expect=2e-23]; ENSG00000171564, FGB, fibrinogen beta chain, [Score=100, Expect=3e-23]; ENSG00000160339, FCN2, ficolin 2, [Score=99.0, Expect=1e-23]} {Mouse: ENSMUSG00000026938, Fcna, ficolin A, [Score=107, Expect=7e-27]; ENSMUSG00000026725, Tnn, tenascin N, [Score=102, Expect=5e-24]; ENSMUSG00000015829, Tnr, tenascin R, [Score=102, Expect=7e-24]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=102, Expect=3e-24]} {Dmel: FBgn0050280, CG30280, [Score=110, Expect=1e-28]} {Celegans: WBGene00012782, Y43C5A.2, [RH, Score=53.1, Expect=8e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=98.2, Expect=5e-23]}
43. MligTC455_50253 44 0.92 Mlig455_031495

Neo: -

Age: -

 GABRB2 2.947 - - 0.975 0.977 - 0.995 Mlig455_031495 {REF} {Length: 2129} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=58.3]} {Human: ENSG00000145864, GABRB2, gamma-aminobutyric acid type A receptor beta2 subunit, [Score=71.2, Expect=6e-14]} {Mouse: ENSMUSG00000007653, Gabrb2, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2, [Score=67.8, Expect=1e-12]; ENSMUSG00000029212, Gabrb1, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1, [Score=67.4, Expect=1e-12]} {Dmel: FBgn0024963, GluClalpha, [Score=54.3, Expect=3e-08]} {Celegans: WBGene00001594, glc-4, Glutamate-gated ChLoride channel, [Score=66.6, Expect=2e-12]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=70.1, Expect=9e-14]} {RNA1310_46931} {RNA815_25428}
44. MligTC455_12084 16 0.34 Mlig455_033067

Neo: -

Age: -

 2.944 - - 0.998 0.948 - 0.998 Mlig455_033067 {REF} {Length: 1019} {RNA1310_38733.1} {RNA815_44268}
45. MligTC455_43715 48 0.99 Mlig455_034191

Neo: -

Age: Down-Up-Down

Region-enriched R2: 7.969/0.00817

 2.942 - - 0.955 0.989 - 0.998 Mlig455_034191 {REF} {Length: 895} {Pfam: WSC domain [PF01822.21, score=39.9]; PAN domain [PF14295.8, score=21.0]; PAN domain [PF00024.28, score=19.9]} {RNA1310_46313} {RNA815_23250}
46. MligTC455_50355 38 0.79 Mlig455_057631

Neo: -

Age: -

Region-enriched R2: 7.639/0.01837

 2.938 - - 0.993 0.950 - 0.995 Mlig455_057631 {REF} {Length: 1003} {Pfam: WSC domain [PF01822.21, score=45.2]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=6e-06]} {RNA1310_44307} {RNA815_33128}
47. MligTC455_11078 15 0.31 Mlig455_045628

Neo: -

Age: -

 2.933 - - 0.987 0.968 - 0.978 Mlig455_045628 {REF} {Length: 2373} {Pfam: Polycystin cation channel [PF08016.14, score=25.4]} {RNA1310_39436.1} {RNA815_35444}
48. MligTC455_32028 19 0.39 Mlig455_019343, Mlig455_019346

Neo: -

Age: -

 GRIA2 2.931 - - 0.997 0.947 - 0.987

Mlig455_019343 {REF} {Length: 3241} {Pfam: Ligand-gated ion channel [PF00060.28, score=96.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=57.9]; Receptor family ligand binding region [PF01094.30, score=49.1]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.0]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=150, Expect=1e-36]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=149, Expect=2e-36]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=146, Expect=2e-35]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=144, Expect=9e-35]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=144, Expect=1e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=150, Expect=5e-37]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=150, Expect=8e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=145, Expect=3e-35]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=3e-35]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=144, Expect=5e-35]} {Dmel: FBgn0039927, CG11155, [Score=158, Expect=1e-39]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=125, Expect=3e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=250, Expect=2e-75]} {RNA1509_10728} {RNA1310_4026} {RNA815_8415.1}

Mlig455_019346 {REF} {Length: 519} {Pfam: Receptor family ligand binding region [PF01094.30, score=21.5]} {RNA1509_10728} {RNA1310_4026} {RNA815_8415.2}
49. MligTC455_33440 62 1.29 Mlig455_053806, Mlig455_053807

Neo: -

Age: Up-Down-Down

Region-enriched R2: 5.142/0.02950

 GRID1 2.93 - - 1.000 0.952 - 0.978

Mlig455_053806 {REF} {Length: 3070} {Pfam: Ligand-gated ion channel [PF00060.28, score=72.9]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=46.7]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=39.8]; Receptor family ligand binding region [PF01094.30, score=28.6]} {Human: ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=145, Expect=2e-35]} {Mouse: ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=143, Expect=2e-34]} {Dmel: FBgn0038837, CG3822, [Score=126, Expect=2e-29]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=112, Expect=3e-25]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=257, Expect=1e-77]} {RNA1310_13880.2} {RNA815_12458}

Mlig455_053807 {REF} {Length: 3142} {Pfam: Ligand-gated ion channel [PF00060.28, score=79.5]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=46.3]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=38.3]; Receptor family ligand binding region [PF01094.30, score=36.5]} {Human: ENSG00000182771, GRID1, glutamate ionotropic receptor delta type subunit 1, [Score=139, Expect=2e-33]} {Mouse: ENSMUSG00000041078, Grid1, glutamate receptor, ionotropic, delta 1, [Score=137, Expect=1e-32]} {Dmel: FBgn0038837, CG3822, [Score=125, Expect=5e-29]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=117, Expect=1e-26]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=259, Expect=2e-78]} {RNA1310_13880.2} {RNA815_12458}
50. MligTC455_10160 19 0.39 Mlig455_006145, Mlig455_006156

Neo: -

Age: -

 2.929 - - 1.000 0.946 - 0.983

Mlig455_006145 {REF} {Length: 984} {Pfam: F5/8 type C domain [PF00754.27, score=28.4]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [Score=64.3, Expect=4e-13]} {RNA1310_84805}

Mlig455_006156 {REF} {Length: 982} {Pfam: F5/8 type C domain [PF00754.27, score=27.7]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [Score=62.8, Expect=1e-12]} {RNA1310_84805}
51. MligTC455_30852 46 0.96 Mlig455_019345, Mlig455_019563, Mlig455_059135

Neo: -

Age: -

 GRIA2, GRIK2, GRIK4 2.926 - - 0.999 0.951 - 0.976

Mlig455_019345 {REF} {Length: 3399} {Pfam: Ligand-gated ion channel [PF00060.28, score=95.4]; Receptor family ligand binding region [PF01094.30, score=56.8]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=44.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=25.8]; Iron-containing alcohol dehydrogenase [PF13685.8, score=21.9]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=159, Expect=1e-39]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=157, Expect=9e-39]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=159, Expect=7e-40]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=155, Expect=2e-38]} {Dmel: FBgn0039927, CG11155, [Score=160, Expect=3e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [RH, Score=281, Expect=4e-87]} {RNA1509_10728} {RNA1310_122.1} {RNA815_8415.1}

Mlig455_019563 {REF} {Length: 2692} {Pfam: Ligand-gated ion channel [PF00060.28, score=91.5]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=98.6, Expect=6e-23]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=95.9, Expect=5e-22]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=94.7, Expect=1e-21]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=96.7, Expect=2e-22]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=95.9, Expect=3e-22]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=94.7, Expect=9e-22]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=92.8, Expect=4e-21]} {Dmel: FBgn0038837, CG3822, [Score=99.4, Expect=2e-23]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=92.8, Expect=2e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=176, Expect=4e-53]} {RNA1310_21734.1} {RNA815_52393}

Mlig455_059135 {REF} {Length: 3434} {Pfam: Receptor family ligand binding region [PF01094.30, score=58.7]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=45.1]; Iron-containing alcohol dehydrogenase [PF13685.8, score=23.1]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=71.6, Expect=2e-12]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=70.5, Expect=3e-12]} {Dmel: FBgn0038837, CG3822, [Score=62.0, Expect=1e-09]} {Celegans: WBGene00001617, glr-6, GLutamate Receptor family (AMPA), [Score=68.6, Expect=6e-12]} {Smed: dd_Smed_v6_41723_0_2, dd_Smed_v6_41723_0_2, [Score=85.1, Expect=8e-18]} {RNA1509_10728} {RNA1310_122.1} {RNA815_8415.1}
52. MligTC455_42245 15 0.32 Mlig455_000580

Neo: -

Age: -

 NOX5 2.924 - - 0.992 0.934 - 0.998 Mlig455_000580 {REF} {Length: 884} {Pfam: EF hand [PF00036.34, score=93.4]; EF-hand domain [PF13405.8, score=85.2]; EF hand [PF13202.8, score=73.1]; EF-hand domain pair [PF13499.8, score=71.3]; EF-hand domain pair [PF13833.8, score=47.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=29.8]; EF-hand domain [PF14658.8, score=21.3]; Caleosin related protein [PF05042.15, score=20.9]; EF-hand domain [PF17958.3, score=19.9]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=19.5]} {Human: ENSG00000255346, NOX5, NADPH oxidase 5, [Score=68.6, Expect=9e-14]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=62.0, Expect=1e-12]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=60.5, Expect=5e-12]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=60.5, Expect=5e-12]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=60.5, Expect=5e-12]} {Dmel: FBgn0033238, azot, ahuizotl, [Score=62.4, Expect=7e-13]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=59.3, Expect=8e-12]} {Smed: dd_Smed_v6_15455_0_1, dd_Smed_v6_15455_0_1, [RH, Score=102, Expect=1e-28]} {RNA1310_74457}
53. MligTC455_38284 12 0.25 Mlig455_015813

Neo: -

Age: -

 2.917 - - 0.948 0.997 - 0.972 Mlig455_015813 {REF} {Length: 1163} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=61.6, Expect=2e-11]} {RNA1310_89599} {RNA815_16968}
54. MligTC455_41540 190 3.96 Mlig455_060056

Neo: -

Age: -

Region-enriched R2: 6.605/0.00196

 GLUL 2.915 0.929 - 0.988 - - 0.998 Mlig455_060056 {REF} {Length: 1355} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=57.3]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=47.5]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=511, Expect=1e-180]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=511, Expect=0.0]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=511, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=515, Expect=0.0]} {Smed: dd_Smed_v6_896_0_1, dd_Smed_v6_896_0_1, [RH, Score=545, Expect=0.0]} {RNA1509_47000} {RNA1310_22329.2} {RNA815_4116.6}
55. MligTC455_45032 56 1.16 Mlig455_034186

Neo: -

Age: -

 KREMEN1 2.914 0.979 - 0.937 - - 0.998 Mlig455_034186 {REF} {Length: 1010} {Pfam: WSC domain [PF01822.21, score=53.3]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=51.2, Expect=3e-07]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=53.9, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=47.8, Expect=3e-06]} {RNA1310_39474.1} {RNA815_33128}
56. MligTC455_15329 22 0.47 Mlig455_060498

Neo: -

Age: -

 2.907 - - 0.953 0.963 - 0.991 Mlig455_060498 {REF} {Length: 1186} {Pfam: PAN domain [PF00024.28, score=18.9]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=63.9, Expect=4e-12]} {RNA1310_37660} {RNA815_17816.1}
57. MligTC455_49451 16 0.34 Mlig455_030374

Neo: -

Age: -

 NOX5 2.907 - - 0.960 0.949 - 0.998 Mlig455_030374 {REF} {Length: 890} {Pfam: EF hand [PF00036.34, score=93.4]; EF-hand domain [PF13405.8, score=86.0]; EF hand [PF13202.8, score=73.1]; EF-hand domain pair [PF13499.8, score=70.3]; EF-hand domain pair [PF13833.8, score=49.3]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=29.0]; EF-hand domain [PF14658.8, score=23.2]; Caleosin related protein [PF05042.15, score=20.4]; EF-hand domain [PF17958.3, score=19.8]} {Human: ENSG00000255346, NOX5, NADPH oxidase 5, [Score=67.4, Expect=2e-13]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=63.5, Expect=3e-13]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=63.2, Expect=4e-13]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=63.2, Expect=4e-13]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=63.2, Expect=4e-13]} {Dmel: FBgn0033238, azot, ahuizotl, [Score=64.3, Expect=1e-13]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=62.4, Expect=6e-13]} {Smed: dd_Smed_v6_15455_0_1, dd_Smed_v6_15455_0_1, [RH, Score=101, Expect=2e-28]} {RNA1310_74457}
58. MligTC455_18748 104 2.17 Mlig455_024985, Mlig455_024999

Neo: -

Age: -

Region-enriched R2: 6.002/0.00016
Region-enriched R4: 3.433/0.02745

 GRIK4 2.905 - - 0.917 0.997 - 0.991

Mlig455_024985 {REF} {Length: 1514} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_47299} {RNA815_38321}

Mlig455_024999 {REF} {Length: 3567} {Pfam: Ligand-gated ion channel [PF00060.28, score=76.7]; Receptor family ligand binding region [PF01094.30, score=31.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=20.6]} {Human: ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=124, Expect=1e-28]} {Dmel: FBgn0038837, CG3822, [Score=120, Expect=1e-27]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=196, Expect=2e-55]} {RNA1509_35538} {RNA1310_7578, RNA1509_35538} {RNA1509_35538, RNA815_4987}
59. MligTC455_25858 48 1 Mlig455_005649, Mlig455_005698, Mlig455_008659

Neo: -

Age: -

 2.895 - - 0.978 0.920 - 0.997

Mlig455_005649 {REF} {Length: 1060} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=27.0]} {RNA1509_35414} {RNA1310_2501.1} {RNA815_9496.1}

Mlig455_005698 {REF} {Length: 1505} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=26.8]} {RNA1509_35414} {RNA1310_2501.1} {RNA815_9496.1}

Mlig455_008659 {REF} {Length: 1151} {TRANSSPLICED} {Pfam: haloacid dehalogenase-like hydrolase [PF08282.14, score=19.9]} {RNA1509_25258} {RNA1310_56236} {RNA815_9496.1}
60. MligTC455_38949 105 2.19 Mlig455_065209

Neo: -

Age: -

Region-specific R2: 7.633

Region-enriched R2: 10.088/0.00000

 2.895 - - 0.901 0.997 - 0.997 Mlig455_065209 {REF} {Length: 591} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=23.2]} {RNA1509_44618} {RNA1310_63839, RNA1509_44618} {RNA1509_44618, RNA815_35329}
61. MligTC455_17177 103 2.15 Mlig455_048992, Mlig455_049009

Neo: -

Age: Down-Down-Up

 2.894 - - 0.908 0.988 - 0.998

Mlig455_048992 {REF} {Length: 1836} {RNA1509_44702} {RNA1310_14743, RNA1509_44702} {RNA1509_44702, RNA815_20669.1}

Mlig455_049009 {REF} {Length: 1823} {RNA1509_44702} {RNA1310_14743} {RNA815_20669.1}
62. MligTC455_29412 46 0.96 Mlig455_000627, Mlig455_008268, Mlig455_040614

Neo: -

Age: Up-Down-Up

 2.885 - - 0.893 0.997 - 0.995

Mlig455_000627 {REF} {Length: 1331} {RNA1310_62571} {RNA815_30942}

Mlig455_008268 {REF} {Length: 1779} {RNA1509_47298} {RNA1310_98344} {RNA815_10804.1}

Mlig455_040614 {REF} {Length: 1016}
63. MligTC455_10899 46 0.95 Mlig455_013784, Mlig455_013915

Neo: -

Age: -

 2.881 - - 0.952 0.957 - 0.972

Mlig455_013784 {REF} {Length: 1362} {Pfam: Glycine rich protein [PF12810.9, score=20.8]} {RNA1509_28715} {RNA1310_91773} {RNA815_35307}

Mlig455_013915 {REF} {Length: 1516} {Pfam: Glycine rich protein [PF12810.9, score=20.3]} {RNA1509_28715} {RNA1310_91773} {RNA815_35307}
64. MligTC455_21681 27 0.56 Mlig455_004824, Mlig455_004903

Neo: -

Age: -

 2.877 - - 1.000 0.965 - 0.912

Mlig455_004824 {REF} {Length: 1006} {Pfam: Lectin C-type domain [PF00059.23, score=26.8]} {Mouse: ENSMUSG00000065987, Cd209b, CD209b antigen, [Score=50.1, Expect=7e-07]; ENSMUSG00000079168, Cd209g, CD209g antigen, [Score=48.1, Expect=2e-06]} {Smed: dd_Smed_v6_85740_0_1, dd_Smed_v6_85740_0_1, [Score=52.0, Expect=1e-08]} {RNA1310_61965} {RNA815_21285}

Mlig455_004903 {REF} {Length: 1008} {Pfam: Lectin C-type domain [PF00059.23, score=26.8]} {Mouse: ENSMUSG00000065987, Cd209b, CD209b antigen, [Score=50.1, Expect=7e-07]; ENSMUSG00000079168, Cd209g, CD209g antigen, [Score=48.1, Expect=2e-06]} {Smed: dd_Smed_v6_85740_0_1, dd_Smed_v6_85740_0_1, [Score=52.0, Expect=1e-08]} {RNA1310_61965} {RNA815_21285}
65. MligTC455_44612 24 0.49 Mlig455_006206, Mlig455_059294

Neo: -

Age: -

 2.873 - - 0.994 - 0.881 0.998

Mlig455_006206 {REF} {Length: 506} {NoTransDecoderORF} {RNA1509_43593} {RNA1310_56719} {RNA815_29718}

Mlig455_059294 {REF} {Length: 1181} {Pfam: PAN domain [PF00024.28, score=19.3]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=66.2, Expect=3e-13]} {RNA1509_35604} {RNA1310_34182} {RNA815_29718}
66. MligTC455_19456 34 0.7 Mlig455_038677

Neo: -

Age: -

 2.873 - - 0.990 0.963 - 0.920 Mlig455_038677 {REF} {Length: 1621} {TRANSSPLICED} {Smed: dd_Smed_v6_15258_0_1, dd_Smed_v6_15258_0_1, [Score=49.3, Expect=4e-07]} {RNA1310_112748}
67. MligTC455_40616 20 0.41 Mlig455_043384, Mlig455_043410

Neo: -

Age: -

 WSCD2 2.87 - - 0.999 0.884 - 0.987

Mlig455_043384 {REF} {Length: 805} {Pfam: WSC domain [PF01822.21, score=54.4]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=57.4, Expect=3e-09]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=57.8, Expect=2e-09]}

Mlig455_043410 {REF} {Length: 804}
68. MligTC455_48521 56 1.17 Mlig455_004444

Neo: -

Age: -

 2.869 0.995 - - 0.977 - 0.897 Mlig455_004444 {REF} {Length: 3968} {Pfam: GDNF/GAS1 domain [PF02351.18, score=19.4]} {Smed: dd_Smed_v6_19517_0_1, dd_Smed_v6_19517_0_1, [RH, Score=111, Expect=3e-25]} {RNA1509_50708} {RNA1310_13399} {RNA815_27009}
69. MligTC455_13903 648 13.5 Mlig455_013116

Neo: -

Age: logFC(26M/2M)=-1.026

Region-specific R2: 6.980

Region-enriched R2: 7.338/0.00000

 2.864 0.929 - - 0.940 - 0.995 Mlig455_013116 {REF} {Length: 914} {RNA1509_28527} {RNA1310_38436.2, RNA1509_28527} {RNA1509_28527, RNA815_28856}
70. MligTC455_15745 27 0.56 Mlig455_040119, Mlig455_067332

Neo: -

Age: -

 ANGPTL2 2.863 - - 0.904 0.961 - 0.998

Mlig455_040119 {REF} {Length: 1066} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=123.8]; PAN domain [PF00024.28, score=20.3]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=102, Expect=5e-24]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=100, Expect=2e-23]; ENSG00000116147, TNR, tenascin R, [Score=100, Expect=2e-23]; ENSG00000120332, TNN, tenascin N, [Score=97.8, Expect=3e-22]} {Mouse: ENSMUSG00000026938, Fcna, ficolin A, [Score=102, Expect=8e-25]; ENSMUSG00000015829, Tnr, tenascin R, [Score=101, Expect=1e-23]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=100, Expect=8e-24]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=100, Expect=1e-23]} {Dmel: FBgn0050280, CG30280, [Score=104, Expect=2e-26]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=105, Expect=2e-25]} {RNA1509_58115} {RNA1310_32877} {RNA815_17241}

Mlig455_067332 {REF} {Length: 1104} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=125.5]; PAN domain [PF00024.28, score=19.2]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=104, Expect=1e-24]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=103, Expect=3e-24]; ENSG00000116147, TNR, tenascin R, [Score=101, Expect=2e-23]} {Mouse: ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=103, Expect=2e-24]; ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=103, Expect=1e-24]; ENSMUSG00000026938, Fcna, ficolin A, [Score=102, Expect=7e-25]; ENSMUSG00000015829, Tnr, tenascin R, [Score=101, Expect=1e-23]} {Dmel: FBgn0050280, CG30280, [Score=107, Expect=2e-27]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=107, Expect=4e-26]} {RNA1509_58115} {RNA1310_32877} {RNA815_17241}
71. MligTC455_42510 125 2.6 Mlig455_025998, Mlig455_070424

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.702

 2.859 - - 0.965 0.895 - 0.999

Mlig455_025998 {REF} {Length: 1369} {RNA1310_73875.1}

Mlig455_070424 {REF} {Length: 1082} {RNA1310_73875.1}
72. MligTC455_18834 33 0.68 Mlig455_000603

Neo: -

Age: -

 2.856 - - 0.862 0.996 - 0.998 Mlig455_000603 {REF} {Length: 1888} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=22.2]} {RNA1310_27913} {RNA815_25050}
73. MligTC455_49854 18 0.37 Mlig455_020520

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.687

 2.854 - - 0.987 0.869 - 0.998 Mlig455_020520 {REF} {Length: 1291} {TRANSSPLICED} {RNA1509_44515} {RNA1310_26152} {RNA815_8882}
74. MligTC455_18682 1190 24.79 Mlig455_037756

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.877

Region-enriched R2: 4.609/0.00000

 2.853 0.872 - 0.984 - - 0.997 Mlig455_037756 {REF} {Length: 1188} {RNA1509_25826} {RNA1310_42757} {RNA815_23874}
75. MligTC455_07122 29 0.61 Mlig455_026687

Neo: -

Age: -

 2.85 - - 0.948 0.971 - 0.931 Mlig455_026687 {REF} {Length: 700} {RNA1310_66647} {RNA815_33955}
76. MligTC455_18775 130 2.71 Mlig455_043349

Neo: -

Age: -

 2.849 - - 0.957 0.899 - 0.993 Mlig455_043349 {REF} {Length: 1583} {RNA1310_56123.1} {RNA815_28679}
77. MligTC455_40989 801 16.68 Mlig455_016294

Neo: -

Age: logFC(26M/2M)=0.270

 PKD2 2.849 0.972 - 0.888 - - 0.989 Mlig455_016294 {REF} {Length: 3179} {Pfam: Polycystin cation channel [PF08016.14, score=486.5]; Ion transport protein [PF00520.33, score=90.3]; EF hand [PF00036.34, score=23.7]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=718, Expect=0.0]; ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [RH, Score=712, Expect=0.0]} {Mouse: ENSMUSG00000037578, Pkd2l1, polycystic kidney disease 2-like 1, [RH, Score=704, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [RH, Score=310, Expect=2e-91]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [RH, Score=370, Expect=7e-116]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_14023, RNA1509_24240} {RNA1310_4836.1, RNA1509_14023, RNA1509_24240} {RNA1509_14023, RNA1509_24240, RNA815_4677}
78. MligTC455_17806 20 0.42 Mlig455_044877

Neo: -

Age: -

 2.847 - - 0.926 0.938 - 0.983 Mlig455_044877 {REF} {Length: 1723} {Pfam: F5/8 type C domain [PF00754.27, score=29.9]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [RH, Score=67.8, Expect=2e-14]} {RNA1310_72359} {RNA815_40265}
79. MligTC455_17178 54 1.12 Mlig455_067758

Neo: -

Age: -

Region-enriched R2: 7.471/0.00007

 2.846 - - 0.865 0.992 - 0.989 Mlig455_067758 {REF} {Length: 2301} {RNA1509_44702} {RNA1310_14743} {RNA815_20669.1}
80. MligTC455_17051 22 0.46 Mlig455_042552

Neo: -

Age: -

 GRIA4 2.842 - - 0.859 0.985 - 0.998 Mlig455_042552 {REF} {Length: 3307} {Pfam: Ligand-gated ion channel [PF00060.28, score=83.3]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=45.2]; Receptor family ligand binding region [PF01094.30, score=25.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.8]} {Human: ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=139, Expect=2e-33]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=139, Expect=3e-33]} {Dmel: FBgn0038837, CG3822, [Score=142, Expect=2e-34]} {Celegans: WBGene00001615, glr-4, GLutamate Receptor family (AMPA), [Score=109, Expect=2e-24]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=246, Expect=7e-74]} {RNA1310_33224} {RNA815_17044}
81. MligTC455_14469 10 0.21 Mlig455_023311

Neo: -

Age: -

 2.841 - - 0.969 0.874 - 0.998 Mlig455_023311 {REF} {Length: 863} {NoTransDecoderORF} {RNA1310_48186} {RNA815_36304}
82. MligTC455_44308 40 0.82 Mlig455_006155

Neo: -

Age: -

Region-enriched R2: 5.931/0.03949
Region-enriched R5: 4.482/0.01958

 2.834 - - 0.955 0.919 - 0.960 Mlig455_006155 {REF} {Length: 1184} {Pfam: F5/8 type C domain [PF00754.27, score=25.5]} {Smed: dd_Smed_v6_52492_0_1, dd_Smed_v6_52492_0_1, [Score=47.8, Expect=4e-07]} {RNA1509_2129} {RNA1310_49415} {RNA815_42540}
83. MligTC455_18099 24 0.51 Mlig455_036525

Neo: -

Age: -

 PPA1 2.833 - - 0.950 0.893 - 0.990 Mlig455_036525 {REF} {Length: 1911} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1310_57333.1} {RNA815_22340}
84. MligTC455_49334 86 1.78 Mlig455_037751

Neo: -

Age: -

 2.833 - - 0.841 0.995 - 0.997 Mlig455_037751 {REF} {Length: 708} {RNA1509_25826} {RNA1310_47741} {RNA815_23874}
85. MligTC455_19079 218 4.54 Mlig455_008746, Mlig455_008760

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.705

Region-enriched R2: 6.864/0.00152

 2.832 - - 0.892 0.957 - 0.983

Mlig455_008746 {REF} {Length: 652} {RNA1310_75395.1} {RNA815_42524}

Mlig455_008760 {REF} {Length: 1051} {RNA1310_75395.1} {RNA815_42524}
86. MligTC455_45020 386 8.05 Mlig455_012422

Neo: -

Age: -

Region-enriched R2: 4.067/0.00066
Region-enriched R3: 2.869/0.01291

 AVP 2.831 - - 0.925 0.942 - 0.964 Mlig455_012422 {REF} {Length: 1252} {Pfam: Neurohypophysial hormones, C-terminal Domain [PF00184.19, score=36.0]} {Human: ENSG00000101200, AVP, arginine vasopressin, [Score=50.4, Expect=4e-08]} {Mouse: ENSMUSG00000037727, Avp, arginine vasopressin, [Score=52.0, Expect=7e-09]} {RNA1509_50574} {RNA1310_26737, RNA1509_50574} {RNA1509_50574, RNA815_23813}
87. MligTC455_27313 61 1.27 Mlig455_031814, Mlig455_047613

Neo: -

Age: -

 WSCD2 2.828 - - 0.943 - 0.889 0.996

Mlig455_031814 {REF} {Length: 844} {Pfam: WSC domain [PF01822.21, score=66.1]; PAN domain [PF00024.28, score=19.7]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=62.0, Expect=7e-11]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=60.5, Expect=1e-10]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=56.6, Expect=3e-09]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=48.5, Expect=1e-06]} {RNA1509_43359} {RNA1310_33892} {RNA815_23776.1}

Mlig455_047613 {REF} {Length: 843} {Pfam: WSC domain [PF01822.21, score=52.5]; PAN domain [PF00024.28, score=19.2]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=52.0, Expect=5e-08]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=48.9, Expect=4e-07]} {RNA1509_43359} {RNA1310_33892} {RNA815_23776.1}
88. MligTC455_50171 151 3.14 Mlig455_065462

Neo: -

Age: logFC(26M/2M)=0.548

Region-specific R2: 5.212

Region-enriched R2: 5.063/0.00089

Regeneration-downregulated R2: -2.783

Regeneration-depleted R2: -2.783

 SCNN1A 2.824 0.958 - - 0.932 - 0.934 Mlig455_065462 {REF} {Length: 3905} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=185.3]} {Human: ENSG00000111319, SCNN1A, sodium channel epithelial 1 alpha subunit, [Score=60.1, Expect=9e-09]} {Mouse: ENSMUSG00000030340, Scnn1a, sodium channel, nonvoltage-gated 1 alpha, [Score=67.0, Expect=5e-11]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=92.8, Expect=1e-19]} {Smed: dd_Smed_v6_16959_0_1, dd_Smed_v6_16959_0_1, [Score=275, Expect=3e-83]} {RNA1509_60030} {RNA1310_56761} {RNA815_31877.1}
89. MligTC455_50455 972 20.25 Mlig455_070346

Neo: -

Age: -

Region-specific R2: 4.855

Region-enriched R2: 5.186/0.00000

 2.823 - - 0.861 0.967 - 0.995 Mlig455_070346 {REF} {Length: 932} {Pfam: Insulin/IGF/Relaxin family [PF00049.20, score=34.4]; Nematode insulin-related peptide beta type [PF03488.16, score=21.4]} {RNA1509_18514, RNA1509_58074} {RNA1310_51990, RNA1509_18514, RNA1509_58074} {RNA1509_18514, RNA1509_58074, RNA815_25071}
90. MligTC455_48756 622 12.96 Mlig455_054772, Mlig455_054799, Mlig455_054893

Neo: -

Age: -

Region-specific R2: 7.873

Region-enriched R2: 9.003/0.00000

 2.822 - - 0.850 0.975 - 0.997

Mlig455_054772 {REF} {Length: 716} {RNA1509_41507} {RNA1310_49516} {RNA815_28703}

Mlig455_054799 {REF} {Length: 625} {RNA1509_41507} {RNA1310_49516} {RNA815_28703}

Mlig455_054893 {REF} {Length: 947} {RNA1509_41507} {RNA1310_49516, RNA1509_41507} {RNA1509_41507, RNA815_28703}
91. MligTC455_37109 33 0.68 Mlig455_060876

Neo: -

Age: -

 2.819 1.000 - 0.833 - - 0.986 Mlig455_060876 {REF} {Length: 929} {NoTransDecoderORF} {RNA1310_114871}
92. MligTC455_37200 32 0.67 Mlig455_030215, Mlig455_030221, Mlig455_067995, Mlig455_067998

Neo: -

Age: -

 2.818 - - 1.000 0.968 - 0.850

Mlig455_030215 {REF} {Length: 1088} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=23.5]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=106, Expect=1e-25]} {RNA1310_102374}

Mlig455_030221 {REF} {Length: 1980} {RNA1310_56149} {RNA815_31265}

Mlig455_067995 {REF} {Length: 792} {Pfam: SAP domain [PF02037.29, score=35.7]} {RNA1509_8096} {RNA1310_1771} {RNA815_801}

Mlig455_067998 {REF} {Length: 1295} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=24.0]} {Smed: dd_Smed_v6_26560_0_2, dd_Smed_v6_26560_0_2, [Score=105, Expect=2e-25]} {RNA1310_102374}
93. MligTC455_46430 62 1.29 Mlig455_057117, Mlig455_069301

Neo: -

Age: -

 GUCY2F 2.815 - - 0.837 0.985 - 0.993

Mlig455_057117 {REF} {Length: 2651} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=196.0]; Nitrate and nitrite sensing [PF08376.12, score=82.5]; Heme NO binding associated [PF07701.16, score=28.2]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=247, Expect=9e-70]; ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=242, Expect=3e-68]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=238, Expect=5e-67]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=246, Expect=7e-70]; ENSMUSG00000027931, Npr1, natriuretic peptide receptor 1, [Score=242, Expect=2e-68]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=241, Expect=7e-68]; ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [Score=239, Expect=3e-67]} {Dmel: FBgn0053958, CG33958, [Score=266, Expect=4e-79]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=235, Expect=3e-66]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=238, Expect=4e-67]} {RNA1509_38781} {RNA1310_35456} {RNA815_22108}

Mlig455_069301 {REF} {Length: 2370} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=178.1]; Nitrate and nitrite sensing [PF08376.12, score=82.3]; Heme NO binding associated [PF07701.16, score=28.0]} {Human: ENSG00000101890, GUCY2F, guanylate cyclase 2F, retinal, [Score=232, Expect=2e-64]} {Mouse: ENSMUSG00000042282, Gucy2f, guanylate cyclase 2f, [Score=232, Expect=1e-64]; ENSMUSG00000020890, Gucy2e, guanylate cyclase 2e, [Score=225, Expect=5e-62]} {Dmel: FBgn0053958, CG33958, [Score=250, Expect=5e-73]} {Celegans: WBGene00001547, gcy-22, Receptor-type guanylate cyclase gcy-22, [Score=223, Expect=1e-61]} {Smed: dd_Smed_v6_14331_0_1, dd_Smed_v6_14331_0_1, [Score=221, Expect=4e-61]} {RNA1509_38781} {RNA1310_35456} {RNA815_24181}
94. MligTC455_10966 15 0.31 Mlig455_013154

Neo: -

Age: -

 2.814 - - 0.965 0.864 - 0.985 Mlig455_013154 {REF} {Length: 827} {Pfam: Lectin C-type domain [PF00059.23, score=21.8]} {RNA1509_20946} {RNA1310_65161} {RNA815_4785.1}
95. MligTC455_17218 37 0.78 Mlig455_053853

Neo: -

Age: -

 2.814 - - 0.830 0.986 - 0.998 Mlig455_053853 {REF} {Length: 1743} {RNA1310_61921}
96. MligTC455_14598 52 1.07 Mlig455_058970

Neo: -

Age: -

 2.805 - - 0.914 0.897 - 0.994 Mlig455_058970 {REF} {Length: 1038} {RNA1310_39570} {RNA815_52309}
97. MligTC455_52128 26 0.54 Mlig455_056382

Neo: -

Age: -

 2.802 - - 0.974 0.864 - 0.964 Mlig455_056382 {REF} {Length: 892} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=20.5]; Ankyrin repeat [PF00023.32, score=19.7]} {RNA1310_149618}
98. MligTC455_12847 25 0.51 Mlig455_049599

Neo: -

Age: -

 2.8 - - 0.934 0.969 - 0.897 Mlig455_049599 {REF} {Length: 1963} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=67.4]; Olfactory receptor [PF13853.8, score=24.7]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=22.0]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.1]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [RH, Score=91.7, Expect=1e-19]} {Smed: dd_Smed_v6_35525_0_1, dd_Smed_v6_35525_0_1, [Score=144, Expect=1e-38]} {RNA1310_85894} {RNA815_45174}
99. MligTC455_35583 48 0.99 Mlig455_009953

Neo: -

Age: -

 2.794 - - 0.901 0.903 - 0.990 Mlig455_009953 {REF} {Length: 919} {Pfam: Lectin C-type domain [PF00059.23, score=25.9]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=61.6, Expect=2e-11]} {RNA1509_20946} {RNA1310_71370} {RNA815_4785.4}
100. MligTC455_35738 32 0.66 Mlig455_043312

Neo: -

Age: -

Region-enriched R4: 7.119/0.01931

 ADGRL2 2.792 - - 0.829 0.978 - 0.985 Mlig455_043312 {REF} {Length: 3897} {Pfam: 7 transmembrane receptor (Secretin family) [PF00002.26, score=111.8]; Myc amino-terminal region [PF01056.20, score=20.2]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [RH, Score=138, Expect=2e-33]} {Mouse: ENSMUSG00000028184, Adgrl2, adhesion G protein-coupled receptor L2, [RH, Score=139, Expect=4e-34]; ENSMUSG00000013033, Adgrl1, adhesion G protein-coupled receptor L1, [RH, Score=136, Expect=3e-33]} {Celegans: WBGene00002252, lat-2, Latrophilin-like protein LAT-2, [Score=118, Expect=1e-27]} {Smed: dd_Smed_v6_16446_0_2, dd_Smed_v6_16446_0_2, [Score=199, Expect=4e-55]} {RNA1509_25495} {RNA1310_3070} {RNA815_2153}

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