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Results for MligTC455_25259

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_25259 108 2.26 Mlig455_016987

Neo: -

Age: -

TMEM30B Mlig455_016987 {REF} {Length: 2255} {TRANSSPLICED} {Pfam: LEM3 (ligand-effect modulator 3) family / CDC50 family [PF03381.17, score=285.6]} {Human: ENSG00000182107, TMEM30B, transmembrane protein 30B, [RH, Score=261, Expect=4e-83]} {Mouse: ENSMUSG00000034435, Tmem30b, transmembrane protein 30B, [RH, Score=253, Expect=2e-80]; ENSMUSG00000032328, Tmem30a, transmembrane protein 30A, [RH, Score=242, Expect=7e-76]} {Dmel: FBgn0030752, CG9947, [RH, Score=307, Expect=2e-101]} {Celegans: WBGene00019946, chat-1, CDC50 family protein chat-1, [RH, Score=287, Expect=9e-94]} {Smed: dd_Smed_v6_6430_0_1, dd_Smed_v6_6430_0_1, [Score=293, Expect=2e-96]} {RNA1509_30971} {RNA1310_19947, RNA1509_30971} {RNA1509_30971, RNA815_8261.1}

Cumulative graph for MligTC455_25259

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.59 2.009 1.00000 1.00000
RegionR2 1.532 2.009 0.25760 0.63810
RegionR3 1.003 2.009 0.37385 0.90776
RegionR4 2.533 2.009 0.05585 0.20793
RegionR5 0.522 2.009 0.57301 0.93134
RegionR6 0.562 2.009 0.58218 1.00000
RegionR7 0.235 2.009 0.72649 1.00000
RegionR8 -4.797 2.009 0.99960 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 5.778 2.009 0.25966 0.96822
RegenerationR2 0.055 2.009 0.91643 1.00000
RegenerationR3 -0.751 2.009 0.33369 0.75904
RegenerationR4 -0.925 2.009 0.29914 0.74127
RegenerationR5 0.046 2.009 0.97711 1.00000
RegenerationR6 -0.202 2.009 0.80926 0.98243
RegenerationBL -2.381 2.009 1.00000 1.00000
RegenerationTP 1.402 2.009 0.53466 0.92342


Genes with expression patterns similar to MligTC455_25259

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_25259 108 2.26 Mlig455_016987

Neo: -

Age: -

TMEM30B 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_016987 {REF} {Length: 2255} {TRANSSPLICED} {Pfam: LEM3 (ligand-effect modulator 3) family / CDC50 family [PF03381.17, score=285.6]} {Human: ENSG00000182107, TMEM30B, transmembrane protein 30B, [RH, Score=261, Expect=4e-83]} {Mouse: ENSMUSG00000034435, Tmem30b, transmembrane protein 30B, [RH, Score=253, Expect=2e-80]; ENSMUSG00000032328, Tmem30a, transmembrane protein 30A, [RH, Score=242, Expect=7e-76]} {Dmel: FBgn0030752, CG9947, [RH, Score=307, Expect=2e-101]} {Celegans: WBGene00019946, chat-1, CDC50 family protein chat-1, [RH, Score=287, Expect=9e-94]} {Smed: dd_Smed_v6_6430_0_1, dd_Smed_v6_6430_0_1, [Score=293, Expect=2e-96]} {RNA1509_30971} {RNA1310_19947, RNA1509_30971} {RNA1509_30971, RNA815_8261.1}
2. MligTC455_42473 118 2.46 Mlig455_016841, Mlig455_016854, Mlig455_070015

Neo: -

Age: -

2.655 - - 0.910 - 0.952 0.793

Mlig455_016841 {REF} {Length: 587} {RNA1310_62504} {RNA815_41252}

Mlig455_016854 {REF} {Length: 587} {RNA1310_62504} {RNA815_41252}

Mlig455_070015 {REF} {Length: 600} {RNA1310_62504} {RNA815_41252}
3. MligTC455_27106 105 2.18 Mlig455_022612

Neo: -

Age: Up-Down-Down

2.639 - - 0.963 - 0.957 0.719 Mlig455_022612 {REF} {Length: 6144} {TRANSSPLICED} {Pfam: TIR domain [PF13676.8, score=157.1]; TIR domain [PF01582.22, score=29.6]; Death domain [PF00531.24, score=29.1]} {Smed: dd_Smed_v6_12177_0_1, dd_Smed_v6_12177_0_1, [RH, Score=638, Expect=0.0]} {RNA1509_29883, RNA1509_42445, RNA1509_47365} {RNA1310_6245, RNA1509_29883, RNA1509_42445, RNA1509_47365} {RNA1509_29883, RNA1509_42445, RNA1509_47365, RNA815_1037}
4. MligTC455_53295 119 2.48 Mlig455_060263

Neo: -

Age: -

LMO4 2.625 - - 0.950 - 0.949 0.726 Mlig455_060263 {REF} {Length: 1717} {Pfam: LIM domain [PF00412.24, score=87.3]} {Human: ENSG00000143013, LMO4, LIM domain only 4, [Score=133, Expect=9e-39]} {Mouse: ENSMUSG00000028266, Lmo4, LIM domain only 4, [Score=133, Expect=6e-39]} {Dmel: FBgn0032196, CG5708, [Score=120, Expect=4e-33]} {Celegans: WBGene00002987, lim-4, LIM domain family; Putative transcription factor LIM-4, [Score=75.5, Expect=9e-16]} {Smed: dd_Smed_v6_27625_0_1, dd_Smed_v6_27625_0_1, [RH, Score=108, Expect=1e-28]} {RNA1509_53632} {RNA1310_25695, RNA1509_53632} {RNA1509_53632, RNA815_42113}
5. MligTC455_32796 106 2.21 Mlig455_059824

Neo: Int S/G2/M

Age: -

2.617 0.749 - - - 0.978 0.890 Mlig455_059824 {REF} {Length: 1634} {TRANSSPLICED} {RNA1509_48912} {RNA1310_29994} {RNA815_2705}
6. MligTC455_36736 652 13.59 Mlig455_019400, Mlig455_059073

Neo: -

Age: Down-Up-Down

Region-enriched R4: 2.387/0.01731

PLCL2 2.538 - - 0.853 - 0.969 0.716

Mlig455_019400 {REF} {Length: 5099} {TRANSSPLICED} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=174.7]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=102.7]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=56.2]; C2 domain [PF00168.32, score=54.1]; Pleckstrin homology domain [PF16457.7, score=29.3]} {Human: ENSG00000284017, PLCL2, phospholipase C like 2, [RH, Score=814, Expect=0.0]; ENSG00000154822, PLCL2, phospholipase C like 2, [RH, Score=814, Expect=0.0]} {Mouse: ENSMUSG00000038910, Plcl2, phospholipase C-like 2, [RH, Score=809, Expect=0.0]} {Dmel: FBgn0004611, Plc21C, Phospholipase C at 21C, [Score=194, Expect=5e-50]} {Celegans: WBGene00004045, pll-1, Phosphoinositide phospholipase C, [RH, Score=719, Expect=0.0]} {Smed: dd_Smed_v6_6102_0_1, dd_Smed_v6_6102_0_1, [RH, Score=935, Expect=0.0]} {RNA1509_8212} {RNA1310_929.2, RNA1509_8212} {RNA1509_8212, RNA815_5686}

Mlig455_059073 {REF} {Length: 5182} {TRANSSPLICED} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=174.7]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=102.7]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=56.2]; C2 domain [PF00168.32, score=54.1]; Pleckstrin homology domain [PF16457.7, score=29.3]} {Human: ENSG00000284017, PLCL2, phospholipase C like 2, [RH, Score=814, Expect=0.0]; ENSG00000154822, PLCL2, phospholipase C like 2, [RH, Score=814, Expect=0.0]} {Mouse: ENSMUSG00000038910, Plcl2, phospholipase C-like 2, [RH, Score=809, Expect=0.0]} {Dmel: FBgn0004611, Plc21C, Phospholipase C at 21C, [Score=194, Expect=5e-50]} {Celegans: WBGene00004045, pll-1, Phosphoinositide phospholipase C, [RH, Score=719, Expect=0.0]} {Smed: dd_Smed_v6_6102_0_1, dd_Smed_v6_6102_0_1, [RH, Score=935, Expect=0.0]} {RNA1509_60150, RNA1509_8212} {RNA1310_929.2, RNA1509_60150} {RNA1509_60150, RNA815_5686}
7. MligTC455_20015 52 1.09 Mlig455_026589

Neo: -

Age: -

1.93 - - 0.950 - 0.980 - Mlig455_026589 {REF} {Length: 611} {RNA1310_66647} {RNA815_33955}
8. MligTC455_14029 53 1.11 Mlig455_022439

Neo: -

Age: -

1.91 - - 0.947 - 0.963 - Mlig455_022439 {REF} {Length: 2874} {RNA1509_36146} {RNA1310_30590} {RNA815_37384}
9. MligTC455_42164 65 1.35 Mlig455_049056

Neo: Int S/G2/M

Age: Down-Up-Down

DR1 1.909 - - 0.963 - 0.946 - Mlig455_049056 {REF} {Length: 1819} {TRANSSPLICED} {Pfam: Histone-like transcription factor (CBF/NF-Y) and archaeal histone [PF00808.25, score=70.7]; Core histone H2A/H2B/H3/H4 [PF00125.26, score=32.0]; CENP-W protein [PF15510.8, score=24.7]} {Human: ENSG00000117505, DR1, down-regulator of transcription 1, [RH, Score=132, Expect=7e-39]} {Mouse: ENSMUSG00000029265, Dr1, down-regulator of transcription 1, [RH, Score=132, Expect=5e-39]} {Dmel: FBgn0028926, NC2beta, Negative Cofactor 2beta, [RH, Score=127, Expect=6e-37]} {Celegans: WBGene00001092, dro-1, DR1 (One) transcription factor family, [RH, Score=90.1, Expect=1e-22]} {Smed: dd_Smed_v6_7479_0_1, dd_Smed_v6_7479_0_1, [RH, Score=125, Expect=2e-36]} {RNA1509_7108} {RNA1310_37108, RNA1509_7108} {RNA1509_7108, RNA815_17293}
10. MligTC455_39838 117 2.44 Mlig455_061337, Mlig455_062688

Neo: -

Age: Up-Down-Down

Region-enriched R2: 5.720/0.01251

PROP1 1.897 - - 0.977 - 0.920 -

Mlig455_061337 {REF} {Length: 2182} {Pfam: Homeodomain [PF00046.31, score=77.0]} {Human: ENSG00000175325, PROP1, PROP paired-like homeobox 1, [RH, Score=97.8, Expect=9e-23]; ENSG00000274382, PROP1, PROP paired-like homeobox 1, [RH, Score=97.8, Expect=9e-23]} {Mouse: ENSMUSG00000028736, Pax7, paired box 7, [Score=103, Expect=4e-23]; ENSMUSG00000036602, Alx1, ALX homeobox 1, [Score=102, Expect=4e-24]; ENSMUSG00000024518, Rax, retina and anterior neural fold homeobox, [Score=101, Expect=3e-23]; ENSMUSG00000035277, Arx, aristaless related homeobox, [Score=100, Expect=4e-22]; ENSMUSG00000040310, Alx4, aristaless-like homeobox 4, [Score=100, Expect=9e-23]; ENSMUSG00000014603, Alx3, aristaless-like homeobox 3, [Score=99.0, Expect=2e-22]} {Dmel: FBgn0052532, CG32532, [RH, Score=188, Expect=3e-55]} {Celegans: WBGene00006778, unc-42, [RH, Score=152, Expect=1e-42]} {Smed: dd_Smed_v6_21801_0_1, dd_Smed_v6_21801_0_1, [RH, Score=211, Expect=9e-63]} {RNA1310_35015.1} {RNA815_23154}

Mlig455_062688 {REF} {Length: 2531} {Pfam: Homeodomain [PF00046.31, score=77.5]} {Human: ENSG00000274382, PROP1, PROP paired-like homeobox 1, [RH, Score=99.0, Expect=1e-23]; ENSG00000175325, PROP1, PROP paired-like homeobox 1, [RH, Score=99.0, Expect=1e-23]} {Mouse: ENSMUSG00000036602, Alx1, ALX homeobox 1, [Score=103, Expect=5e-25]; ENSMUSG00000028736, Pax7, paired box 7, [Score=103, Expect=5e-24]; ENSMUSG00000024518, Rax, retina and anterior neural fold homeobox, [Score=102, Expect=4e-24]; ENSMUSG00000040310, Alx4, aristaless-like homeobox 4, [Score=102, Expect=8e-24]; ENSMUSG00000035277, Arx, aristaless related homeobox, [Score=101, Expect=4e-23]; ENSMUSG00000014603, Alx3, aristaless-like homeobox 3, [Score=100, Expect=2e-23]; ENSMUSG00000004872, Pax3, paired box 3, [Score=99.4, Expect=2e-22]; ENSMUSG00000012520, Phox2b, paired-like homeobox 2b, [Score=98.2, Expect=7e-23]} {Dmel: FBgn0052532, CG32532, [RH, Score=189, Expect=2e-56]} {Celegans: WBGene00006778, unc-42, [RH, Score=155, Expect=1e-44]} {Smed: dd_Smed_v6_21801_0_1, dd_Smed_v6_21801_0_1, [RH, Score=212, Expect=2e-64]} {RNA1310_35015.1} {RNA815_23154}
11. MligTC455_32267 35 0.74 Mlig455_050248

Neo: -

Age: -

1.888 - - 0.931 - 0.957 - Mlig455_050248 {REF} {Length: 1579} {Pfam: Lectin C-type domain [PF00059.23, score=33.1]} {RNA1310_32476} {RNA815_61830}
12. MligTC455_09938 37 0.78 Mlig455_063017

Neo: -

Age: -

1.883 - - - - 0.973 0.910 Mlig455_063017 {REF} {Length: 881} {NoTransDecoderORF}
13. MligTC455_07526 28 0.58 Mlig455_070319

Neo: -

Age: logFC(26M/2M)=-2.717

1.879 - - 0.924 - 0.955 - Mlig455_070319 {REF} {Length: 1163} {Pfam: TRP-interacting helix [PF15018.8, score=32.1]} {RNA1509_36146} {RNA1310_68496} {RNA815_7310}
14. MligTC455_28071 128 2.68 Mlig455_005176

Neo: -

Age: -

1.863 - - - - 0.960 0.903 Mlig455_005176 {REF} {Length: 1665} {NoTransDecoderORF} {RNA1509_38430} {RNA1310_48089} {RNA815_51074}
15. MligTC455_36543 145 3.03 Mlig455_067860

Neo: -

Age: Down-Up-Up

MFSD8 1.853 0.874 - - - 0.979 - Mlig455_067860 {REF} {Length: 3751} {Pfam: Major Facilitator Superfamily [PF07690.18, score=87.6]} {Human: ENSG00000164073, MFSD8, major facilitator superfamily domain containing 8, [Score=61.2, Expect=2e-09]} {Mouse: ENSMUSG00000116169, Mfsd8, major facilitator superfamily domain containing 8, [Score=58.2, Expect=2e-09]; ENSMUSG00000025759, Mfsd8, major facilitator superfamily domain containing 8, [Score=58.2, Expect=2e-09]} {Smed: dd_Smed_v6_9883_0_1, dd_Smed_v6_9883_0_1, [RH, Score=369, Expect=7e-123]} {RNA1509_54938} {RNA1310_19930} {RNA815_20915}
16. MligTC455_23567 109 2.27 Mlig455_013185

Neo: -

Age: Down-Up-Down

BCHE 1.835 - - 0.868 - 0.967 - Mlig455_013185 {REF} {Length: 4455} {Pfam: Carboxylesterase family [PF00135.30, score=432.1]; alpha/beta hydrolase fold [PF07859.15, score=35.5]} {Human: ENSG00000114200, BCHE, butyrylcholinesterase, [Score=317, Expect=9e-99]; ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=312, Expect=2e-96]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [Score=324, Expect=3e-101]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=249, Expect=8e-73]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=327, Expect=2e-102]} {Smed: dd_Smed_v6_15930_0_1, dd_Smed_v6_15930_0_1, [RH, Score=412, Expect=4e-134]} {RNA1509_26775} {RNA1310_8383.1} {RNA815_10983}
17. MligTC455_41254 59 1.23 Mlig455_052520

Neo: Int S/G2/M

Age: -

1.826 - - - - 0.967 0.859 Mlig455_052520 {REF} {Length: 8122} {Smed: dd_Smed_v6_24483_0_1, dd_Smed_v6_24483_0_1, [Score=85.5, Expect=3e-18]} {RNA1509_53555} {RNA1310_50995} {RNA815_38632}
18. MligTC455_19114 79 1.64 Mlig455_045107

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.813

1.825 - - 0.854 - 0.971 - Mlig455_045107 {REF} {Length: 1513} {Pfam: F5/8 type C domain [PF00754.27, score=20.0]} {RNA1509_57504} {RNA1310_27303.2} {RNA815_32964}
19. MligTC455_52066 838 17.45 Mlig455_024600

Neo: Int S/G2/M

Age: -

Region-enriched R4: 1.542/0.00420

RTN4 1.815 - - - 0.855 0.960 - Mlig455_024600 {REF} {Length: 2031} {TRANSSPLICED} {Pfam: Reticulon [PF02453.19, score=87.5]} {Human: ENSG00000115310, RTN4, reticulon 4, [RH, Score=87.4, Expect=9e-19]} {Mouse: ENSMUSG00000020458, Rtn4, reticulon 4, [RH, Score=88.2, Expect=8e-21]} {Dmel: FBgn0053113, Rtnl1, Reticulon-like1, [RH, Score=103, Expect=1e-24]} {Smed: dd_Smed_v6_4451_0_1, dd_Smed_v6_4451_0_1, [RH, Score=58.2, Expect=3e-10]} {RNA1509_25959, RNA1509_31648, RNA1509_48670} {RNA1310_34226, RNA1509_25959, RNA1509_31648, RNA1509_48670} {RNA1509_25959, RNA1509_31648, RNA1509_48670, RNA815_15914}
20. MligTC455_12088 61 1.26 Mlig455_057931, Mlig455_057966

Neo: -

Age: -

1.81 0.829 - 0.981 - - -

Mlig455_057931 {REF} {Length: 396} {RNA1310_75258} {RNA815_44558}

Mlig455_057966 {REF} {Length: 396} {RNA1310_75258} {RNA815_44558}
21. MligTC455_18191 426 8.88 Mlig455_013109, Mlig455_013200

Neo: -

Age: -

1.808 - - - 0.840 0.968 -

Mlig455_013109 {REF} {Length: 1736} {TRANSSPLICED} {Pfam: THAP domain [PF05485.14, score=49.6]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=28.1]; Anti-sigma-K factor rskA [PF10099.11, score=23.9]} {RNA1509_21728, RNA1509_53612} {RNA1310_31334.1, RNA1509_53612} {RNA1509_53612, RNA815_35876}

Mlig455_013200 {REF} {Length: 2209} {TRANSSPLICED} {Pfam: THAP domain [PF05485.14, score=49.6]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=27.8]; Anti-sigma-K factor rskA [PF10099.11, score=23.8]} {RNA1509_21728, RNA1509_43501} {RNA1310_31334.1, RNA1509_21728} {RNA1509_21728, RNA815_35876}
22. MligTC455_17684 157 3.26 Mlig455_041455

Neo: Irradiation

Age: Up-Down-Down

ASPG 1.807 - - 0.828 - 0.979 - Mlig455_041455 {REF} {Length: 5938} {TRANSSPLICED} {Pfam: Asparaginase, N-terminal [PF00710.22, score=202.1]; Glutaminase/Asparaginase C-terminal domain [PF17763.3, score=84.6]; Ankyrin repeats (many copies) [PF13857.8, score=64.3]; Ankyrin repeats (3 copies) [PF12796.9, score=59.0]; Ankyrin repeats (many copies) [PF13637.8, score=54.0]; Ankyrin repeat [PF13606.8, score=43.8]; Ankyrin repeat [PF00023.32, score=35.8]} {Human: ENSG00000166183, ASPG, asparaginase, [Score=346, Expect=7e-110]} {Mouse: ENSMUSG00000037686, Aspg, asparaginase, [Score=340, Expect=9e-108]} {Dmel: FBgn0029689, CG6428, [RH, Score=439, Expect=2e-145]} {Celegans: WBGene00007756, C27A7.5, [Score=412, Expect=1e-134]} {Smed: dd_Smed_v6_7816_0_1, dd_Smed_v6_7816_0_1, [RH, Score=426, Expect=7e-140]} {RNA1509_11582, RNA1509_16816, RNA1509_8667} {RNA1310_8678, RNA1509_16816, RNA1509_8667} {RNA1509_16816, RNA1509_8667, RNA815_6302}
23. MligTC455_28428 622 12.96 Mlig455_054840

Neo: Neoblast, stringent

Age: -

NDC80 1.804 - - - 0.851 0.953 - Mlig455_054840 {REF} {Length: 2970} {TRANSSPLICED} {Pfam: HEC/Ndc80p family [PF03801.15, score=36.5]} {Human: ENSG00000080986, NDC80, NDC80, kinetochore complex component, [RH, Score=63.9, Expect=5e-10]} {Mouse: ENSMUSG00000024056, Ndc80, NDC80 kinetochore complex component, [RH, Score=63.2, Expect=6e-10]} {RNA1509_20133, RNA1509_31470} {RNA1310_11007.1, RNA1509_20133, RNA1509_31470} {RNA1509_20133, RNA1509_31470, RNA815_13191}
24. MligTC455_21535 290 6.05 Mlig455_014603

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

1.791 0.830 - - - 0.961 - Mlig455_014603 {REF} {Length: 2779} {Pfam: Amnionless [PF14828.8, score=88.5]} {RNA1509_36645} {RNA1310_11582, RNA1509_36645} {RNA1509_36645, RNA815_5314}
25. MligTC455_16672 41 0.86 Mlig455_019194

Neo: -

Age: -

Region-enriched R2: 5.301/0.02053

1.788 - - 0.812 - 0.976 - Mlig455_019194 {REF} {Length: 648} {RNA1310_52751} {RNA815_26203}
26. MligTC455_43178 271 5.65 Mlig455_041380

Neo: -

Age: -

1.782 - - 0.815 - 0.967 - Mlig455_041380 {REF} {Length: 804} {RNA1509_7702} {RNA1310_9214} {RNA815_28262.1}
27. MligTC455_15250 145 3.01 Mlig455_066748

Neo: -

Age: -

1.78 - - - - 0.985 0.795 Mlig455_066748 {REF} {Length: 647} {NoTransDecoderORF} {RNA1509_52333, RNA1509_55685, RNA1509_56537} {RNA1310_27819, RNA1509_52333, RNA1509_55685} {RNA1509_52333, RNA1509_55685, RNA815_25553}
28. MligTC455_46311 178 3.71 Mlig455_024248

Neo: -

Age: Down-Up-Down

NISCH 1.776 0.810 - - - 0.966 - Mlig455_024248 {REF} {Length: 4779} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=44.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=40.7]; Leucine rich repeat [PF13855.8, score=33.7]; PX domain [PF00787.26, score=25.6]} {Human: ENSG00000010322, NISCH, nischarin, [Score=298, Expect=8e-91]} {Mouse: ENSMUSG00000021910, Nisch, nischarin, [Score=286, Expect=1e-86]} {Dmel: FBgn0033996, CG11807, [Score=201, Expect=7e-56]} {Celegans: WBGene00008750, F13E9.1, [Score=188, Expect=2e-51]} {Smed: dd_Smed_v6_8533_0_5, dd_Smed_v6_8533_0_5, [Score=196, Expect=4e-54]} {RNA1509_31748} {RNA1310_12578} {RNA815_13327}
29. MligTC455_07144 15 0.32 Mlig455_006549

Neo: -

Age: logFC(26M/2M)=-0.763

1.774 - - 0.950 - - 0.824 Mlig455_006549 {REF} {Length: 1713} {RNA1509_10027} {RNA1310_19729} {RNA815_11599}
30. MligTC455_45403 60 1.26 Mlig455_001365

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.466

SLC6A5 1.774 - - - - 0.964 0.810 Mlig455_001365 {REF} {Length: 6779} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=804.8]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=421, Expect=2e-128]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=423, Expect=4e-129]} {Dmel: FBgn0034911, CG5549, [Score=396, Expect=8e-116]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=342, Expect=1e-102]} {Smed: dd_Smed_v6_4290_0_1, dd_Smed_v6_4290_0_1, [Score=389, Expect=9e-120]} {RNA1509_14194} {RNA1310_1653.1} {RNA815_6812}
31. MligTC455_20957 40 0.84 Mlig455_009152

Neo: -

Age: -

1.764 - - 0.812 - 0.952 - Mlig455_009152 {REF} {Length: 1951} {RNA1310_39190} {RNA815_29274}
32. MligTC455_47975 31 0.64 Mlig455_018682, Mlig455_043427

Neo: -

Age: Up-Down-Down

ISL1 1.762 - - 0.974 - - 0.788

Mlig455_018682 {REF} {Length: 3387} {Pfam: LIM domain [PF00412.24, score=95.5]; Homeodomain [PF00046.31, score=55.3]; Homeobox KN domain [PF05920.13, score=23.7]} {Human: ENSG00000016082, ISL1, ISL LIM homeobox 1, [Score=202, Expect=6e-60]} {Mouse: ENSMUSG00000042258, Isl1, ISL1 transcription factor, LIM/homeodomain, [Score=202, Expect=4e-60]} {Dmel: FBgn0003896, tup, tailup, [RH, Score=178, Expect=3e-49]} {Celegans: WBGene00002989, lim-7, CeLIM-7; LIM domain family, [RH, Score=228, Expect=5e-69]} {Smed: dd_Smed_v6_8820_0_1, dd_Smed_v6_8820_0_1, [Score=320, Expect=1e-103]} {RNA1310_20628} {RNA815_37694}

Mlig455_043427 {REF} {Length: 3365} {Pfam: LIM domain [PF00412.24, score=77.4]; Homeodomain [PF00046.31, score=53.3]; Homeobox KN domain [PF05920.13, score=21.8]} {Human: ENSG00000016082, ISL1, ISL LIM homeobox 1, [Score=167, Expect=2e-46]} {Mouse: ENSMUSG00000042258, Isl1, ISL1 transcription factor, LIM/homeodomain, [Score=167, Expect=1e-46]; ENSMUSG00000032318, Isl2, insulin related protein 2 (islet 2), [Score=160, Expect=4e-44]} {Dmel: FBgn0003896, tup, tailup, [Score=144, Expect=1e-37]} {Celegans: WBGene00002989, lim-7, CeLIM-7; LIM domain family, [Score=204, Expect=6e-60]} {Smed: dd_Smed_v6_8820_0_1, dd_Smed_v6_8820_0_1, [Score=274, Expect=7e-86]} {RNA1310_20628} {RNA815_37694}
33. MligTC455_11818 167 3.49 Mlig455_064965

Neo: -

Age: Down-Up-Down

TTC30B 1.753 - - - - 0.956 0.797 Mlig455_064965 {REF} {Length: 2662} {Human: ENSG00000196659, TTC30B, tetratricopeptide repeat domain 30B, [Score=202, Expect=5e-62]; ENSG00000197557, TTC30A, tetratricopeptide repeat domain 30A, [Score=198, Expect=2e-60]} {Mouse: ENSMUSG00000075271, Ttc30a1, tetratricopeptide repeat domain 30A1, [Score=205, Expect=4e-63]; ENSMUSG00000075272, Ttc30a2, tetratricopeptide repeat domain 30A2, [Score=202, Expect=5e-62]; ENSMUSG00000075273, Ttc30b, tetratricopeptide repeat domain 30B, [Score=201, Expect=8e-62]} {Dmel: FBgn0032470, CG5142, [Score=94.4, Expect=6e-23]} {Celegans: WBGene00001117, dyf-1, Tetratricopeptide repeat protein 30 homolog, [Score=138, Expect=8e-39]} {Smed: dd_Smed_v6_8798_0_1, dd_Smed_v6_8798_0_1, [Score=224, Expect=1e-70]} {RNA1509_15421} {RNA1310_6112} {RNA815_1970}
34. MligTC455_24400 237 4.93 Mlig455_007323, Mlig455_068326

Neo: -

Age: -

KCNAB2 1.742 - - 0.773 - 0.969 -

Mlig455_007323 {REF} {Length: 3488} {Pfam: Aldo/keto reductase family [PF00248.23, score=187.7]} {Human: ENSG00000069424, KCNAB2, potassium voltage-gated channel subfamily A regulatory beta subunit 2, [RH, Score=502, Expect=1e-175]; ENSG00000169282, KCNAB1, potassium voltage-gated channel subfamily A member regulatory beta subunit 1, [RH, Score=481, Expect=2e-166]} {Mouse: ENSMUSG00000028931, Kcnab2, potassium voltage-gated channel, shaker-related subfamily, beta member 2, [RH, Score=505, Expect=8e-177]; ENSMUSG00000027827, Kcnab1, potassium voltage-gated channel, shaker-related subfamily, beta member 1, [RH, Score=481, Expect=1e-166]} {Dmel: FBgn0263220, Hk, Hyperkinetic, [RH, Score=322, Expect=3e-99]} {Celegans: WBGene00015565, C07D8.6, [Score=58.9, Expect=3e-09]} {RNA1509_10965} {RNA1310_75287} {RNA815_44952}

Mlig455_068326 {REF} {Length: 3179} {Pfam: Aldo/keto reductase family [PF00248.23, score=181.5]} {Human: ENSG00000069424, KCNAB2, potassium voltage-gated channel subfamily A regulatory beta subunit 2, [RH, Score=453, Expect=2e-161]} {Mouse: ENSMUSG00000028931, Kcnab2, potassium voltage-gated channel, shaker-related subfamily, beta member 2, [Score=458, Expect=7e-163]} {Dmel: FBgn0263220, Hk, Hyperkinetic, [Score=294, Expect=1e-97]} {Celegans: WBGene00015565, C07D8.6, [Score=49.7, Expect=1e-06]} {RNA1509_10965} {RNA1310_87215.1} {RNA815_44952}
35. MligTC455_38506 150 3.12 Mlig455_006635

Neo: Int S/G2/M

Age: Up-Down-Down

HASPIN 1.741 - - - 0.788 0.953 - Mlig455_006635 {REF} {Length: 3890} {TRANSSPLICED} {Pfam: Haspin like kinase domain [PF12330.10, score=186.0]; Protein kinase domain [PF00069.27, score=19.2]} {Human: ENSG00000177602, HASPIN, histone H3 associated protein kinase, [Score=225, Expect=1e-62]} {Mouse: ENSMUSG00000050107, Haspin, histone H3 associated protein kinase, [Score=226, Expect=2e-63]} {Dmel: FBgn0046706, Haspin, [RH, Score=226, Expect=4e-65]} {Celegans: WBGene00007258, hasp-1, HASPin kinase related, [Score=193, Expect=2e-51]} {Smed: dd_Smed_v6_12380_0_1, dd_Smed_v6_12380_0_1, [Score=265, Expect=6e-79]} {RNA1509_15378, RNA1509_37794} {RNA1310_5814.1, RNA1509_37794} {RNA1509_37794, RNA815_8825}
36. MligTC455_11819 202 4.22 Mlig455_064964, Mlig455_066821

Neo: -

Age: -

TTC30B 1.737 - - - - 0.953 0.784

Mlig455_064964 {REF} {Length: 1221} {Human: ENSG00000196659, TTC30B, tetratricopeptide repeat domain 30B, [Score=124, Expect=5e-31]; ENSG00000197557, TTC30A, tetratricopeptide repeat domain 30A, [Score=123, Expect=9e-31]} {Mouse: ENSMUSG00000075271, Ttc30a1, tetratricopeptide repeat domain 30A1, [Score=147, Expect=2e-39]; ENSMUSG00000075273, Ttc30b, tetratricopeptide repeat domain 30B, [Score=146, Expect=5e-39]; ENSMUSG00000075272, Ttc30a2, tetratricopeptide repeat domain 30A2, [Score=141, Expect=2e-37]} {Dmel: FBgn0032470, CG5142, [Score=86.7, Expect=1e-18]} {Celegans: WBGene00001117, dyf-1, Tetratricopeptide repeat protein 30 homolog, [Score=95.5, Expect=1e-21]} {Smed: dd_Smed_v6_8798_0_1, dd_Smed_v6_8798_0_1, [Score=163, Expect=1e-45]} {RNA1509_26165} {RNA1310_6112} {RNA815_1970}

Mlig455_066821 {REF} {Length: 2805} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF14559.8, score=59.8]; Tetratricopeptide repeat [PF07719.19, score=57.0]; Tetratricopeptide repeat [PF13424.8, score=45.3]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=42.1]; Tetratricopeptide repeat [PF13428.8, score=38.1]; Tetratricopeptide repeat [PF00515.30, score=37.3]; Tetratricopeptide repeat [PF13432.8, score=35.9]; Tetratricopeptide repeat [PF13176.8, score=26.5]; Tetratricopeptide repeat [PF13371.8, score=20.0]; TPR repeat [PF13414.8, score=19.8]} {Human: ENSG00000196659, TTC30B, tetratricopeptide repeat domain 30B, [RH, Score=870, Expect=0.0]; ENSG00000197557, TTC30A, tetratricopeptide repeat domain 30A, [RH, Score=866, Expect=0.0]} {Mouse: ENSMUSG00000075271, Ttc30a1, tetratricopeptide repeat domain 30A1, [RH, Score=868, Expect=0.0]; ENSMUSG00000075273, Ttc30b, tetratricopeptide repeat domain 30B, [RH, Score=864, Expect=0.0]; ENSMUSG00000075272, Ttc30a2, tetratricopeptide repeat domain 30A2, [RH, Score=855, Expect=0.0]} {Dmel: FBgn0032470, CG5142, [RH, Score=537, Expect=0.0]} {Celegans: WBGene00001117, dyf-1, Tetratricopeptide repeat protein 30 homolog, [RH, Score=596, Expect=0.0]} {Smed: dd_Smed_v6_8798_0_1, dd_Smed_v6_8798_0_1, [RH, Score=984, Expect=0.0]} {RNA1509_15421, RNA1509_26165} {RNA1310_6112, RNA1509_15421, RNA1509_26165} {RNA1509_15421, RNA1509_26165, RNA815_1970}
37. MligTC455_26196 33 0.7 Mlig455_015355, Mlig455_023904

Neo: -

Age: Down-Up-Up

FCN1 1.733 - - 0.968 - - 0.765

Mlig455_015355 {REF} {Length: 1003} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=168.4]} {Human: ENSG00000085265, FCN1, ficolin 1, [Score=133, Expect=3e-36]; ENSG00000160339, FCN2, ficolin 2, [Score=127, Expect=6e-34]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=127, Expect=4e-34]; ENSMUSG00000026938, Fcna, ficolin A, [Score=125, Expect=2e-33]; ENSMUSG00000028364, Tnc, tenascin C, [Score=122, Expect=1e-30]; ENSMUSG00000033327, Tnxb, tenascin XB, [Score=122, Expect=1e-30]; ENSMUSG00000015829, Tnr, tenascin R, [Score=122, Expect=2e-30]} {Dmel: FBgn0033312, CG8642, [Score=106, Expect=7e-26]} {Celegans: WBGene00017013, ensh-1, [Score=52.4, Expect=2e-07]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=113, Expect=4e-28]} {RNA1310_44670.1} {RNA815_23388}

Mlig455_023904 {REF} {Length: 4417} {RNA1509_17406} {RNA1310_3508, RNA1509_17406} {RNA1509_17406, RNA815_3588}
38. MligTC455_43116 105 2.2 Mlig455_006245, Mlig455_006299, Mlig455_061192

Neo: -

Age: -

ESRRB 1.729 - - 0.773 - 0.956 -

Mlig455_006245 {REF} {Length: 450} {NoTransDecoderORF}

Mlig455_006299 {REF} {Length: 2539} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.3]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=20.3]} {Human: ENSG00000119715, ESRRB, estrogen related receptor beta, [Score=94.4, Expect=2e-20]} {Mouse: ENSMUSG00000047638, Nr1h4, nuclear receptor subfamily 1, group H, member 4, [Score=88.2, Expect=1e-18]; ENSMUSG00000024955, Esrra, estrogen related receptor, alpha, [Score=86.7, Expect=3e-18]; ENSMUSG00000015846, Rxra, retinoid X receptor alpha, [Score=85.1, Expect=1e-17]; ENSMUSG00000023034, Nr4a1, nuclear receptor subfamily 4, group A, member 1, [Score=84.7, Expect=2e-17]} {Dmel: FBgn0035849, ERR, estrogen-related receptor, [Score=80.9, Expect=3e-16]} {Celegans: WBGene00003625, nhr-31, Nuclear hormone receptor family member nhr-31, [Score=84.3, Expect=2e-17]} {Smed: dd_Smed_v6_3012_0_1, dd_Smed_v6_3012_0_1, [Score=81.3, Expect=1e-16]} {RNA1310_86523}

Mlig455_061192 {REF} {Length: 2120} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.2]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=19.6]} {Human: ENSG00000119715, ESRRB, estrogen related receptor beta, [Score=97.4, Expect=2e-21]} {Mouse: ENSMUSG00000047638, Nr1h4, nuclear receptor subfamily 1, group H, member 4, [Score=94.4, Expect=1e-20]} {Dmel: FBgn0035849, ERR, estrogen-related receptor, [Score=80.1, Expect=4e-16]} {Celegans: WBGene00003625, nhr-31, Nuclear hormone receptor family member nhr-31, [Score=84.3, Expect=2e-17]} {Smed: dd_Smed_v6_13691_0_1, dd_Smed_v6_13691_0_1, [Score=79.7, Expect=1e-16]} {RNA1310_86523}
39. MligTC455_16760 96 2 Mlig455_039271

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.283/0.01201

CDKL2 1.728 - - - - 0.964 0.764 Mlig455_039271 {REF} {Length: 4664} {Pfam: Protein kinase domain [PF00069.27, score=242.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=123.9]; ABC1 atypical kinase-like domain [PF03109.18, score=17.9]} {Human: ENSG00000138769, CDKL2, cyclin dependent kinase like 2, [RH, Score=445, Expect=3e-150]} {Mouse: ENSMUSG00000029403, Cdkl2, cyclin-dependent kinase-like 2 (CDC2-related kinase), [RH, Score=427, Expect=3e-143]} {Dmel: FBgn0031730, CG7236, [Score=332, Expect=3e-108]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [Score=337, Expect=1e-111]} {Smed: dd_Smed_v6_17162_0_1, dd_Smed_v6_17162_0_1, [RH, Score=412, Expect=2e-140]} {RNA1509_31808} {RNA1310_11068.1} {RNA815_5716}
40. MligTC455_37352 210 4.37 Mlig455_012059

Neo: Int S/G2/M

Age: -

RNASEH2A 1.724 - - - - 0.963 0.761 Mlig455_012059 {REF} {Length: 1775} {TRANSSPLICED} {Pfam: Ribonuclease HII [PF01351.20, score=153.5]} {Human: ENSG00000104889, RNASEH2A, ribonuclease H2 subunit A, [RH, Score=232, Expect=4e-74]} {Mouse: ENSMUSG00000052926, Rnaseh2a, ribonuclease H2, large subunit, [RH, Score=234, Expect=5e-75]} {Dmel: FBgn0031252, CG13690, [RH, Score=226, Expect=1e-71]} {Celegans: WBGene00004383, rnh-2, Ribonuclease H2 subunit A, [RH, Score=231, Expect=3e-74]} {Smed: dd_Smed_v6_10404_0_1, dd_Smed_v6_10404_0_1, [RH, Score=261, Expect=8e-86]} {RNA1509_29004} {RNA1310_30632} {RNA815_10850}
41. MligTC455_41028 108 2.26 Mlig455_033278

Neo: -

Age: -

1.723 - - 0.751 - 0.972 - Mlig455_033278 {REF} {Length: 1134} {Pfam: PAN domain [PF00024.28, score=19.4]} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=68.2, Expect=9e-14]} {RNA1310_31986} {RNA815_17816.2}
42. MligTC455_08660 30 0.63 Mlig455_005536

Neo: -

Age: logFC(26M/2M)=-0.847

1.721 0.740 - 0.981 - - - Mlig455_005536 {REF} {Length: 3312} {RNA1509_30152, RNA1509_46404} {RNA1310_20821, RNA1509_30152, RNA1509_46404} {RNA1509_30152, RNA1509_46404, RNA815_3479.2}
43. MligTC455_16952 79 1.65 Mlig455_001182

Neo: -

Age: -

1.72 - 0.756 0.964 - - - Mlig455_001182 {REF} {Length: 3873} {Smed: dd_Smed_v6_17523_0_1, dd_Smed_v6_17523_0_1, [RH, Score=67.0, Expect=3e-14]} {RNA1509_4618} {RNA1310_46281} {RNA815_28578}
44. MligTC455_08528 31 0.66 Mlig455_014271

Neo: -

Age: -

1.715 - - 0.969 - - 0.746 Mlig455_014271 {REF} {Length: 744} {NoTransDecoderORF} {RNA1509_8600} {RNA1310_31185} {RNA815_4566}
45. MligTC455_52482 22 0.46 Mlig455_042671

Neo: -

Age: -

1.714 0.751 - 0.963 - - - Mlig455_042671 {REF} {Length: 2390} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=150.1]} {Smed: dd_Smed_v6_31771_0_1, dd_Smed_v6_31771_0_1, [Score=71.2, Expect=6e-13]} {RNA1310_47540} {RNA815_16144}
46. MligTC455_45719 94 1.96 Mlig455_056535

Neo: -

Age: -

CHRNA6 1.713 - - - - 0.961 0.752 Mlig455_056535 {REF} {Length: 2532} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=102.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=75.5]} {Human: ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [Score=127, Expect=1e-31]; ENSG00000166736, HTR3A, 5-hydroxytryptamine receptor 3A, [Score=125, Expect=4e-31]} {Mouse: ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=125, Expect=5e-31]; ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=120, Expect=1e-29]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=117, Expect=4e-28]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=125, Expect=3e-31]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=122, Expect=4e-30]} {RNA1509_7752} {RNA1310_37530} {RNA815_18433}
47. MligTC455_17806 20 0.42 Mlig455_044877

Neo: -

Age: -

1.71 - - 0.981 - - 0.729 Mlig455_044877 {REF} {Length: 1723} {Pfam: F5/8 type C domain [PF00754.27, score=29.9]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [RH, Score=67.8, Expect=2e-14]} {RNA1310_72359} {RNA815_40265}
48. MligTC455_28085 58 1.2 Mlig455_003072

Neo: -

Age: Up-Down-Up

FAM57A 1.707 - - 0.960 - - 0.747 Mlig455_003072 {REF} {Length: 4271} {tRNA: Lys(TTT), score=88.9} {Pfam: TLC domain [PF03798.18, score=91.3]} {Human: ENSG00000167695, FAM57A, family with sequence similarity 57 member A, [Score=100, Expect=8e-25]} {Mouse: ENSMUSG00000069808, Fam57a, family with sequence similarity 57, member A, [Score=114, Expect=4e-30]} {RNA1509_56219} {RNA1310_22473.1, RNA1509_56219} {RNA1509_56219, RNA815_13618.1}
49. MligTC455_18100 17 0.36 Mlig455_069127

Neo: -

Age: -

PPA1 1.702 - - 0.967 - - 0.735 Mlig455_069127 {REF} {Length: 2015} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1509_39915} {RNA1310_57333.1} {RNA815_22340}
50. MligTC455_39383 57 1.18 Mlig455_018466

Neo: -

Age: -

ZFP62 1.702 - - 0.961 - 0.741 - Mlig455_018466 {REF} {Length: 5302} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=101.9]; C2H2-type zinc finger [PF13894.8, score=91.9]; C2H2-type zinc finger [PF13912.8, score=44.2]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=34.4]; Zinc-finger of C2H2 type [PF12874.9, score=31.7]} {Human: ENSG00000196670, ZFP62, ZFP62 zinc finger protein, [Score=92.4, Expect=4e-18]; ENSG00000198440, ZNF583, zinc finger protein 583, [Score=90.5, Expect=8e-18]; ENSG00000256771, ZNF253, zinc finger protein 253, [Score=87.8, Expect=2e-17]} {Mouse: ENSMUSG00000030443, Zfp583, zinc finger protein 583, [Score=89.4, Expect=1e-17]; ENSMUSG00000057101, Zfp180, zinc finger protein 180, [Score=88.2, Expect=4e-17]; ENSMUSG00000046311, Zfp62, zinc finger protein 62, [Score=87.8, Expect=7e-17]; ENSMUSG00000095362, Gm14325, predicted gene 14325, [Score=87.8, Expect=3e-17]; ENSMUSG00000037001, Zfp39, zinc finger protein 39, [Score=85.1, Expect=3e-16]} {Dmel: FBgn0020309, crol, crooked legs, [Score=80.5, Expect=8e-15]} {Celegans: WBGene00021931, Y55F3AM.14, [Score=73.6, Expect=7e-13]} {RNA1509_43194} {RNA1310_1292} {RNA815_2738.1}
51. MligTC455_47613 35 0.72 Mlig455_002169, Mlig455_002268

Neo: -

Age: Up-Down-Down

CASP8 1.701 - - 0.974 - - 0.727

Mlig455_002169 {REF} {Length: 2630} {Pfam: Caspase domain [PF00656.24, score=102.9]; Ankyrin repeats (3 copies) [PF12796.9, score=88.0]; Ankyrin repeats (many copies) [PF13857.8, score=71.4]; Ankyrin repeat [PF00023.32, score=59.2]; Ankyrin repeats (many copies) [PF13637.8, score=56.4]; Ankyrin repeat [PF13606.8, score=27.9]} {Human: ENSG00000064012, CASP8, caspase 8, [Score=132, Expect=4e-33]; ENSG00000132906, CASP9, caspase 9, [Score=129, Expect=1e-32]; ENSG00000165806, CASP7, caspase 7, [Score=127, Expect=3e-32]} {Mouse: ENSMUSG00000026029, Casp8, caspase 8, [Score=135, Expect=2e-34]} {Dmel: FBgn0028381, Decay, Death executioner caspase related to Apopain/Yama, [Score=101, Expect=1e-23]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=94.7, Expect=2e-21]} {Smed: dd_Smed_v6_4986_0_1, dd_Smed_v6_4986_0_1, [Score=124, Expect=1e-32]} {RNA1310_16714.1} {RNA815_15476}

Mlig455_002268 {REF} {Length: 2678} {Pfam: Caspase domain [PF00656.24, score=103.1]; Ankyrin repeats (many copies) [PF13857.8, score=75.2]; Ankyrin repeats (3 copies) [PF12796.9, score=60.1]; Ankyrin repeat [PF00023.32, score=57.0]; Ankyrin repeats (many copies) [PF13637.8, score=53.0]; Ankyrin repeat [PF13606.8, score=28.1]} {Human: ENSG00000064012, CASP8, caspase 8, [Score=131, Expect=7e-33]; ENSG00000132906, CASP9, caspase 9, [Score=129, Expect=8e-33]; ENSG00000164305, CASP3, caspase 3, [Score=127, Expect=9e-33]; ENSG00000165806, CASP7, caspase 7, [Score=127, Expect=8e-32]} {Mouse: ENSMUSG00000026029, Casp8, caspase 8, [Score=131, Expect=8e-33]} {Dmel: FBgn0028381, Decay, Death executioner caspase related to Apopain/Yama, [Score=100, Expect=2e-23]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=94.4, Expect=2e-21]} {Smed: dd_Smed_v6_4986_0_1, dd_Smed_v6_4986_0_1, [Score=124, Expect=3e-32]} {RNA1310_16714.1} {RNA815_15476}
52. MligTC455_43095 294 6.13 Mlig455_028880

Neo: -

Age: -

Region-enriched R2: 5.606/0.00021

1.7 - - 0.727 - 0.973 - Mlig455_028880 {REF} {Length: 822} {RNA1509_32622} {RNA1310_67920, RNA1509_32622} {RNA1509_32622, RNA815_31932.2}
53. MligTC455_32478 197 4.11 Mlig455_007115

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.445

CPT1A 1.69 - - - 0.737 0.953 - Mlig455_007115 {REF} {Length: 4545} {TRANSSPLICED} {Pfam: Choline/Carnitine o-acyltransferase [PF00755.22, score=531.9]} {Human: ENSG00000110090, CPT1A, carnitine palmitoyltransferase 1A, [Score=530, Expect=6e-178]} {Mouse: ENSMUSG00000024900, Cpt1a, carnitine palmitoyltransferase 1a, liver, [Score=527, Expect=9e-177]; ENSMUSG00000078937, Cpt1b, carnitine palmitoyltransferase 1b, muscle, [Score=507, Expect=4e-169]} {Dmel: FBgn0261862, whd, withered, [Score=539, Expect=0.0]} {Celegans: WBGene00012907, cpt-1, Carnitine Palmitoyl Transferase, [Score=496, Expect=6e-165]} {Smed: dd_Smed_v6_5302_0_1, dd_Smed_v6_5302_0_1, [RH, Score=787, Expect=0.0]} {RNA1509_23085, RNA1509_31169, RNA1509_34311, RNA1509_58117} {RNA1310_6605.1, RNA1509_31169, RNA1509_34311, RNA1509_58117} {RNA1509_31169, RNA1509_34311, RNA1509_58117, RNA815_2729.1}
54. MligTC455_19582 125 2.6 Mlig455_063355

Neo: -

Age: -

1.688 - - - - 0.953 0.735 Mlig455_063355 {REF} {Length: 2588} {TRANSSPLICED} {Pfam: Coiled-coil domain-containing protein 24 family [PF15669.7, score=98.8]} {Smed: dd_Smed_v6_16835_0_1, dd_Smed_v6_16835_0_1, [Score=105, Expect=3e-27]} {RNA1310_34434} {RNA815_28600}
55. MligTC455_20294 341 7.11 Mlig455_007896, Mlig455_008003

Neo: -

Age: Up-Down-Down

Region-enriched R8: 3.032/0.04842

LRRK2 1.685 - - - - 0.957 0.728

Mlig455_007896 {REF} {Length: 11344} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=164.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=71.6]; TIR domain [PF13676.8, score=57.4]; Leucine rich repeat [PF13855.8, score=43.0]; Ras family [PF00071.24, score=38.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=24.8]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=167, Expect=3e-40]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=166, Expect=5e-40]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=145, Expect=7e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=125, Expect=4e-28]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=723, Expect=0.0]} {RNA1509_8727} {RNA1310_292.1, RNA1509_8727} {RNA1509_8727, RNA815_1320}

Mlig455_008003 {REF} {Length: 11209} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=160.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=72.4]; TIR domain [PF13676.8, score=59.5]; Leucine rich repeat [PF13855.8, score=45.2]; Ras family [PF00071.24, score=39.6]; Leucine Rich repeats (2 copies) [PF12799.9, score=28.4]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=167, Expect=1e-40]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=163, Expect=1e-39]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=145, Expect=4e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=120, Expect=1e-26]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=686, Expect=0.0]} {RNA1509_8727} {RNA1310_292.1} {RNA815_1320}
56. MligTC455_18184 135 2.8 Mlig455_057491

Neo: -

Age: -

1.684 - - 0.728 - 0.956 - Mlig455_057491 {REF} {Length: 1846} {RNA1509_15768, RNA1509_22100} {RNA1310_3010, RNA1509_15768} {RNA1509_15768, RNA815_592.2}
57. MligTC455_42059 387 8.07 Mlig455_062377

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.538

GFAP 1.684 0.720 - - - 0.964 - Mlig455_062377 {REF} {Length: 3972} {Pfam: Intermediate filament protein [PF00038.23, score=152.8]; Myosin tail [PF01576.21, score=25.9]; Protein SOGA [PF11365.10, score=20.3]} {Human: ENSG00000131095, GFAP, glial fibrillary acidic protein, [Score=109, Expect=5e-25]; ENSG00000113368, LMNB1, lamin B1, [Score=105, Expect=1e-23]; ENSG00000160789, LMNA, lamin A/C, [Score=105, Expect=3e-23]} {Mouse: ENSMUSG00000026208, Des, desmin, [Score=112, Expect=6e-26]; ENSMUSG00000020932, Gfap, glial fibrillary acidic protein, [Score=107, Expect=1e-24]} {Dmel: FBgn0010397, LamC, Lamin C, [Score=140, Expect=3e-35]} {Celegans: WBGene00002050, ifa-1, Intermediate filament protein ifa-1, [Score=239, Expect=1e-71]} {Smed: dd_Smed_v6_3871_0_1, dd_Smed_v6_3871_0_1, [Score=284, Expect=1e-88]} {RNA1509_17658, RNA1509_42622, RNA1509_50182} {RNA1310_10237.1, RNA1509_42622, RNA1509_50182} {RNA1509_42622, RNA1509_50182, RNA815_9230.1}
58. MligTC455_19426 45 0.94 Mlig455_055478

Neo: -

Age: -

1.682 - - - 0.721 - 0.961 Mlig455_055478 {REF} {Length: 2102} {NoTransDecoderORF} {RNA1509_60145} {RNA1310_87383} {RNA815_53511}
59. MligTC455_53464 112 2.32 Mlig455_022873, Mlig455_031316, Mlig455_051326, Mlig455_059151, Mlig455_065537, Mlig455_068954

Neo: -

Age: -

1.68 - - - - 0.966 0.714

Mlig455_022873 {REF} {Length: 699} {RNA1509_39955} {RNA1310_18913} {RNA815_8758}

Mlig455_031316 {REF} {Length: 509} {NoTransDecoderORF} {RNA1509_39955} {RNA1310_18913} {RNA815_8758}

Mlig455_051326 {REF} {Length: 413} {NoTransDecoderORF} {RNA1509_39955} {RNA1310_18913} {RNA815_8758}

Mlig455_059151 {REF} {Length: 1208} {Pfam: PIF1-like helicase [PF05970.16, score=47.9]} {Smed: dd_Smed_v6_29278_0_1, dd_Smed_v6_29278_0_1, [Score=45.4, Expect=9e-07]} {RNA1310_3236.1} {RNA815_8758}

Mlig455_065537 {REF} {Length: 1924} {Pfam: PIF1-like helicase [PF05970.16, score=196.8]; AAA domain [PF13604.8, score=21.4]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=58.5, Expect=1e-08]} {Celegans: WBGene00018020, F33H12.6, [Score=120, Expect=2e-28]} {Smed: dd_Smed_v6_18512_0_3, dd_Smed_v6_18512_0_3, [Score=52.4, Expect=2e-08]} {RNA1310_3236.1} {RNA815_8758}

Mlig455_068954 {REF} {Length: 106} {NoTransDecoderORF} {RNA1310_15811.1} {RNA815_61788}
60. MligTC455_20722 36 0.74 Mlig455_001696, Mlig455_066078, Mlig455_066120

Neo: -

Age: -

1.679 - - 0.956 - - 0.723

Mlig455_001696 {REF} {Length: 1535} {RNA1310_134737} {RNA815_57224}

Mlig455_066078 {REF} {Length: 1438} {Pfam: Glycine rich protein [PF12810.9, score=20.4]} {RNA1310_134737} {RNA815_57224}

Mlig455_066120 {REF} {Length: 1438} {Pfam: Glycine rich protein [PF12810.9, score=25.9]} {RNA1310_134737} {RNA815_57224}
61. MligTC455_41857 148 3.08 Mlig455_037828

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.788

BRD8 1.677 - - 0.720 - 0.957 - Mlig455_037828 {REF} {Length: 2010} {TRANSSPLICED} {Pfam: Bromodomain [PF00439.27, score=33.1]} {Human: ENSG00000112983, BRD8, bromodomain containing 8, [Score=69.3, Expect=9e-12]} {Mouse: ENSMUSG00000003778, Brd8, bromodomain containing 8, [Score=69.3, Expect=7e-12]} {Dmel: FBgn0050417, tbrd-3, testis-specifically expressed bromodomain containing protein-3, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_10362_1_1, dd_Smed_v6_10362_1_1, [RH, Score=57.0, Expect=1e-08]} {RNA1509_27181} {RNA1310_17527} {RNA815_26572}
62. MligTC455_23555 418 8.71 Mlig455_013595

Neo: -

Age: -

DNAJC4 1.675 - - - 0.707 0.968 - Mlig455_013595 {REF} {Length: 2081} {TRANSSPLICED} {Pfam: DnaJ domain [PF00226.33, score=67.2]} {Human: ENSG00000110011, DNAJC4, DnaJ heat shock protein family (Hsp40) member C4, [RH, Score=67.4, Expect=5e-13]; ENSG00000176410, DNAJC30, DnaJ heat shock protein family (Hsp40) member C30, [RH, Score=64.7, Expect=4e-12]} {Mouse: ENSMUSG00000014905, Dnajb9, DnaJ heat shock protein family (Hsp40) member B9, [Score=67.4, Expect=3e-13]} {Dmel: FBgn0037544, CG11035, [Score=65.5, Expect=1e-12]} {Celegans: WBGene00001022, dnj-4, DNaJ domain (Prokaryotic heat shock protein), [RH, Score=58.9, Expect=3e-10]} {Smed: dd_Smed_v6_3393_0_1, dd_Smed_v6_3393_0_1, [RH, Score=72.0, Expect=1e-15]} {RNA1509_17877, RNA1509_20487, RNA1509_27055, RNA1509_35237, RNA1509_47036, RNA1509_54606, RNA1509_56854} {RNA1310_22951, RNA1509_17877, RNA1509_20487, RNA1509_27055, RNA1509_35237, RNA1509_47036, RNA1509_54606, RNA1509_56854} {RNA1509_17877, RNA1509_20487, RNA1509_27055, RNA1509_35237, RNA1509_47036, RNA1509_54606, RNA1509_56854, RNA815_9786}
63. MligTC455_39804 351 7.32 Mlig455_026117, Mlig455_026177

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.434

1.672 - - - - 0.958 0.714

Mlig455_026117 {REF} {Length: 1701} {Pfam: Immunoglobulin domain [PF13927.8, score=48.1]; Immunoglobulin I-set domain [PF07679.18, score=47.3]; Immunoglobulin domain [PF00047.27, score=33.0]; Immunoglobulin V-set domain [PF07686.19, score=30.6]} {Dmel: FBgn0037993, dpr15, defective proboscis extension response 15, [RH, Score=52.8, Expect=3e-07]} {Smed: dd_Smed_v6_22736_0_1, dd_Smed_v6_22736_0_1, [RH, Score=73.9, Expect=1e-14]} {RNA1310_21460} {RNA815_8845.1}

Mlig455_026177 {REF} {Length: 1111} {Pfam: Immunoglobulin domain [PF13927.8, score=41.5]; Immunoglobulin I-set domain [PF07679.18, score=39.2]; Immunoglobulin domain [PF00047.27, score=26.5]; Immunoglobulin V-set domain [PF07686.19, score=23.8]} {Dmel: FBgn0267428, CG45781, [Score=50.1, Expect=2e-06]} {Smed: dd_Smed_v6_22736_0_1, dd_Smed_v6_22736_0_1, [Score=67.8, Expect=1e-12]} {RNA1310_21460} {RNA815_8845.1}
64. MligTC455_21765 62 1.3 Mlig455_031149

Neo: -

Age: Down-Up-Up

STOM 1.671 - 0.715 0.956 - - - Mlig455_031149 {REF} {Length: 2538} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=114.7]} {Human: ENSG00000148175, STOM, stomatin, [RH, Score=361, Expect=1e-124]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=347, Expect=1e-119]} {Dmel: FBgn0260657, CG42540, [RH, Score=380, Expect=3e-131]} {Celegans: WBGene00006064, sto-2, Stomatin-2, [RH, Score=385, Expect=1e-133]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=387, Expect=2e-135]} {RNA1509_9137} {RNA1310_23238} {RNA815_24338}
65. MligTC455_36790 22 0.47 Mlig455_020283

Neo: -

Age: Up-Down-Up

PLEKHH3 1.671 - - 0.964 - - 0.707 Mlig455_020283 {REF} {Length: 4575} {Pfam: MyTH4 domain [PF00784.19, score=55.4]} {Human: ENSG00000068137, PLEKHH3, pleckstrin homology, MyTH4 and FERM domain containing H3, [RH, Score=55.8, Expect=1e-07]} {Mouse: ENSMUSG00000035172, Plekhh3, pleckstrin homology domain containing, family H (with MyTH4 domain) member 3, [RH, Score=55.8, Expect=1e-07]} {Dmel: FBgn0267431, Myo81F, Myosin 81F, [Score=69.3, Expect=6e-12]} {Smed: dd_Smed_v6_19214_0_1, dd_Smed_v6_19214_0_1, [Score=168, Expect=3e-45]} {RNA1310_45564} {RNA815_42536}
66. MligTC455_18099 24 0.51 Mlig455_036525

Neo: -

Age: -

PPA1 1.67 - - 0.967 - - 0.703 Mlig455_036525 {REF} {Length: 1911} {Pfam: Inorganic pyrophosphatase [PF00719.21, score=181.8]} {Human: ENSG00000180817, PPA1, pyrophosphatase (inorganic) 1, [Score=304, Expect=2e-103]; ENSG00000138777, PPA2, pyrophosphatase (inorganic) 2, [Score=295, Expect=4e-99]} {Mouse: ENSMUSG00000020089, Ppa1, pyrophosphatase (inorganic) 1, [Score=307, Expect=9e-105]} {Dmel: FBgn0016687, Nurf-38, Nucleosome remodeling factor - 38kD, [Score=303, Expect=2e-103]} {Celegans: WBGene00008149, pyp-1, Probable inorganic pyrophosphatase 1, [Score=315, Expect=5e-108]} {Smed: dd_Smed_v6_625_0_1, dd_Smed_v6_625_0_1, [Score=290, Expect=2e-98]} {RNA1310_57333.1} {RNA815_22340}
67. MligTC455_47313 364 7.58 Mlig455_058672

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.435

LUC7L 1.665 - - 0.701 - 0.964 - Mlig455_058672 {REF} {Length: 2574} {Pfam: LUC7 N_terminus [PF03194.17, score=239.7]} {Human: ENSG00000007392, LUC7L, LUC7 like, [RH, Score=303, Expect=7e-99]; ENSG00000146963, LUC7L2, LUC7 like 2, pre-mRNA splicing factor, [RH, Score=293, Expect=9e-95]} {Mouse: ENSMUSG00000024188, Luc7l, Luc7-like, [RH, Score=303, Expect=8e-99]; ENSMUSG00000029823, Luc7l2, LUC7-like 2 (S. cerevisiae), [RH, Score=290, Expect=2e-94]} {Dmel: FBgn0036734, CG7564, [RH, Score=306, Expect=2e-99]} {Celegans: WBGene00015207, B0495.8, [RH, Score=161, Expect=2e-45]} {Smed: dd_Smed_v6_4536_0_4, dd_Smed_v6_4536_0_4, [RH, Score=300, Expect=3e-99]} {RNA1509_894} {RNA1310_9024.1} {RNA815_807.1}
68. MligTC455_11078 15 0.31 Mlig455_045628

Neo: -

Age: -

1.664 - - 0.952 - - 0.712 Mlig455_045628 {REF} {Length: 2373} {Pfam: Polycystin cation channel [PF08016.14, score=25.4]} {RNA1310_39436.1} {RNA815_35444}
69. MligTC455_49228 14 0.28 Mlig455_052327

Neo: -

Age: -

0.988 - - 0.988 - - - Mlig455_052327 {REF} {Length: 1429} {Smed: dd_Smed_v6_47882_0_1, dd_Smed_v6_47882_0_1, [Score=45.4, Expect=1e-05]} {RNA1310_43249}
70. MligTC455_53175 150 3.12 Mlig455_024313, Mlig455_024369

Neo: -

Age: -

0.988 - - - - 0.988 -

Mlig455_024313 {REF} {Length: 800} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=59.2]} {Dmel: FBgn0013467, igl, igloo, [Score=66.6, Expect=6e-12]} {Smed: dd_Smed_v6_4783_0_67, dd_Smed_v6_4783_0_67, [Score=75.1, Expect=3e-14]} {RNA1310_37981}

Mlig455_024369 {REF} {Length: 562} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=59.2]} {Dmel: FBgn0013467, igl, igloo, [Score=66.6, Expect=6e-12]} {Smed: dd_Smed_v6_4783_0_67, dd_Smed_v6_4783_0_67, [Score=75.1, Expect=3e-14]} {RNA1310_37981}
71. MligTC455_20268 11 0.23 Mlig455_007616

Neo: -

Age: -

0.987 - - 0.987 - - - Mlig455_007616 {REF} {Length: 1727} {RNA1509_46103} {RNA1310_64930} {RNA815_36286}
72. MligTC455_20354 66 1.38 Mlig455_043446

Neo: -

Age: -

0.987 - - - - 0.987 - Mlig455_043446 {REF} {Length: 2134} {NoTransDecoderORF} {RNA1509_49770} {RNA1310_75709} {RNA815_12664}
73. MligTC455_43206 528 11.01 Mlig455_057920

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.327

CACNB2 0.984 - - - - 0.984 - Mlig455_057920 {REF} {Length: 4131} {Pfam: Guanylate kinase [PF00625.23, score=145.1]; Voltage gated calcium channel subunit beta domain 4Aa N terminal [PF12052.10, score=25.7]} {Human: ENSG00000165995, CACNB2, calcium voltage-gated channel auxiliary subunit beta 2, [RH, Score=475, Expect=2e-161]; ENSG00000067191, CACNB1, calcium voltage-gated channel auxiliary subunit beta 1, [RH, Score=456, Expect=5e-156]} {Mouse: ENSMUSG00000057914, Cacnb2, calcium channel, voltage-dependent, beta 2 subunit, [RH, Score=465, Expect=8e-158]; ENSMUSG00000020882, Cacnb1, calcium channel, voltage-dependent, beta 1 subunit, [RH, Score=454, Expect=2e-155]; ENSMUSG00000017412, Cacnb4, calcium channel, voltage-dependent, beta 4 subunit, [RH, Score=442, Expect=1e-150]} {Dmel: FBgn0259822, Ca-beta, Ca2+-channel-protein-beta-subunit, [RH, Score=482, Expect=2e-163]} {Celegans: WBGene00000368, ccb-1, Calcium Channel, Beta subunit, [RH, Score=446, Expect=3e-152]} {Smed: dd_Smed_v6_9267_0_1, dd_Smed_v6_9267_0_1, [RH, Score=471, Expect=6e-162]} {RNA1509_14590, RNA1509_38024, RNA1509_46998} {RNA1310_10661, RNA1509_38024, RNA1509_46998} {RNA1509_38024, RNA1509_46998, RNA815_4109}
74. MligTC455_44323 393 8.19 Mlig455_065375

Neo: -

Age: -

UPF3A 0.984 - - - - 0.984 - Mlig455_065375 {REF} {Length: 2017} {TRANSSPLICED} {Pfam: Smg-4/UPF3 family [PF03467.17, score=133.0]} {Human: ENSG00000169062, UPF3A, UPF3A, regulator of nonsense mediated mRNA decay, [RH, Score=107, Expect=1e-24]; ENSG00000125351, UPF3B, UPF3B, regulator of nonsense mediated mRNA decay, [RH, Score=105, Expect=3e-24]} {Mouse: ENSMUSG00000036572, Upf3b, UPF3 regulator of nonsense transcripts homolog B (yeast), [RH, Score=107, Expect=4e-25]} {Dmel: FBgn0034923, Upf3, [RH, Score=114, Expect=2e-27]} {Celegans: WBGene00004882, smg-4, Suppressor with Morphological effect on Genitalia, [RH, Score=74.7, Expect=2e-14]} {RNA1509_14867, RNA1509_20383} {RNA1310_13461, RNA1509_14867, RNA1509_20383} {RNA1509_14867, RNA1509_20383, RNA815_1079.1}
75. MligTC455_29071 125 2.61 Mlig455_058077, Mlig455_061708

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.937

0.983 - - - - 0.983 -

Mlig455_058077 {REF} {Length: 1960} {RNA1509_39229} {RNA1310_12556.2, RNA1509_39229} {RNA1509_39229, RNA815_5170.1}

Mlig455_061708 {REF} {Length: 1938} {RNA1509_39229} {RNA1310_12556.2} {RNA815_5170.1}
76. MligTC455_43363 58 1.22 Mlig455_002291

Neo: -

Age: -

Region-enriched R2: 5.574/0.01843

0.983 - - - - 0.983 - Mlig455_002291 {REF} {Length: 2912} {TRANSSPLICED} {Smed: dd_Smed_v6_9636_0_1, dd_Smed_v6_9636_0_1, [RH, Score=130, Expect=9e-32]} {RNA1509_37248} {RNA1310_12152.1} {RNA815_8090}
77. MligTC455_36378 34 0.71 Mlig455_046249

Neo: -

Age: -

Region-enriched R5: 3.006/0.04602

NWD2 0.981 - - 0.981 - - - Mlig455_046249 {REF} {Length: 5234} {Pfam: AAA ATPase domain [PF13191.8, score=37.9]; NACHT domain [PF05729.14, score=28.9]; WD domain, G-beta repeat [PF00400.34, score=27.1]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=363, Expect=1e-101]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=355, Expect=2e-99]} {Dmel: FBgn0038397, CG10185, [Score=827, Expect=0.0]} {Celegans: WBGene00020254, T05C3.2, [Score=827, Expect=0.0]} {Smed: dd_Smed_v6_11085_0_2, dd_Smed_v6_11085_0_2, [Score=336, Expect=2e-93]} {RNA1310_71275}
78. MligTC455_53114 8 0.16 Mlig455_049581

Neo: -

Age: -

0.981 - - 0.981 - - - Mlig455_049581 {REF} {Length: 1044} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=45.2]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [Score=58.2, Expect=8e-10]}
79. MligTC455_22910 103 2.14 Mlig455_040130

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.273

TMEM214 0.98 - - - - 0.980 - Mlig455_040130 {REF} {Length: 3719} {Pfam: TMEM214, C-terminal, caspase 4 activator [PF10151.11, score=88.6]} {Human: ENSG00000119777, TMEM214, transmembrane protein 214, [RH, Score=58.9, Expect=2e-08]} {Mouse: ENSMUSG00000038828, Tmem214, transmembrane protein 214, [RH, Score=61.2, Expect=3e-09]} {RNA1509_7642} {RNA1310_10501} {RNA815_16505}
80. MligTC455_29069 229 4.78 Mlig455_017646, Mlig455_017647, Mlig455_024259

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.506

0.98 - - - - 0.980 -

Mlig455_017646 {REF} {Length: 1950} {RNA1509_39229} {RNA1310_12556.2} {RNA815_5170.1}

Mlig455_017647 {REF} {Length: 3033} {RNA1509_54862} {RNA1310_63.1} {RNA815_5170.1}

Mlig455_024259 {REF} {Length: 1876} {RNA1509_39229} {RNA1310_12556.2} {RNA815_5170.1}
81. MligTC455_45523 528 11 Mlig455_063535

Neo: -

Age: Up-Down-Down

DCAF6 0.98 - - - - 0.980 - Mlig455_063535 {REF} {Length: 3252} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=57.5]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=24.9]} {Human: ENSG00000143164, DCAF6, DDB1 and CUL4 associated factor 6, [RH, Score=174, Expect=2e-45]} {Mouse: ENSMUSG00000026571, Dcaf6, DDB1 and CUL4 associated factor 6, [RH, Score=177, Expect=1e-46]} {Dmel: FBgn0000057, adp, adipose, [Score=105, Expect=1e-23]} {Celegans: WBGene00044440, adpr-1, ADiPose (Drosophila obesity gene) Related, [Score=77.4, Expect=1e-14]} {Smed: dd_Smed_v6_5540_0_1, dd_Smed_v6_5540_0_1, [Score=110, Expect=4e-25]} {RNA1509_11637} {RNA1310_10014.2} {RNA815_7894.1}
82. MligTC455_16687 7 0.14 Mlig455_036499

Neo: -

Age: -

0.979 - - 0.979 - - - Mlig455_036499 {REF} {Length: 1102} {RNA1509_52280} {RNA1310_45283}
83. MligTC455_17842 957 19.93 Mlig455_070916

Neo: -

Age: -

NARS 0.979 - - - - 0.979 - Mlig455_070916 {REF} {Length: 2687} {TRANSSPLICED} {Pfam: tRNA synthetases class II (D, K and N) [PF00152.22, score=332.3]; OB-fold nucleic acid binding domain [PF01336.27, score=43.3]} {Human: ENSG00000134440, NARS, asparaginyl-tRNA synthetase, [RH, Score=737, Expect=0.0]} {Mouse: ENSMUSG00000024587, Nars, asparaginyl-tRNA synthetase, [RH, Score=723, Expect=0.0]} {Dmel: FBgn0086443, AsnRS, Asparaginyl-tRNA synthetase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00003815, nars-1, Asparagine--tRNA ligase, cytoplasmic, [RH, Score=623, Expect=0.0]} {Smed: dd_Smed_v6_2691_0_1, dd_Smed_v6_2691_0_1, [RH, Score=587, Expect=0.0]} {RNA1509_5093} {RNA1310_14490, RNA1509_5093} {RNA1509_5093, RNA815_5353}
84. MligTC455_36485 54 1.13 Mlig455_019921, Mlig455_059996, Mlig455_060437

Neo: -

Age: -

0.979 - - 0.979 - - -

Mlig455_019921 {REF} {Length: 215} {NoTransDecoderORF} {RNA1509_26293} {RNA1310_22958} {RNA815_52664}

Mlig455_059996 {REF} {Length: 1701} {NoTransDecoderORF} {RNA1509_26293} {RNA1310_22958} {RNA815_52664}

Mlig455_060437 {REF} {Length: 4172} {NoTransDecoderORF} {RNA1509_55514} {RNA1310_37194} {RNA815_10967.1}
85. MligTC455_50130 149 3.11 Mlig455_000637

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.523

0.979 - - - - 0.979 - Mlig455_000637 {REF} {Length: 3012} {RNA1509_32590} {RNA1310_8641.2, RNA1509_32590} {RNA1509_32590, RNA815_3178.1}
86. MligTC455_51020 106 2.2 Mlig455_017827

Neo: -

Age: -

0.979 - - - - 0.979 - Mlig455_017827 {REF} {Length: 2829} {RNA1509_46951} {RNA1310_31396} {RNA815_47704}
87. MligTC455_06241 31 0.65 Mlig455_028634

Neo: -

Age: -

0.978 - - - - 0.978 - Mlig455_028634 {REF} {Length: 411} {NoTransDecoderORF} {RNA1509_39395} {RNA1310_113479} {RNA815_51346.2}
88. MligTC455_17340 117 2.43 Mlig455_056518

Neo: -

Age: -

CHRNA3 0.978 - - - - 0.978 - Mlig455_056518 {REF} {Length: 2896} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=68.3]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=63.9, Expect=1e-11]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=59.7, Expect=2e-10]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=59.3, Expect=3e-10]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=57.0, Expect=2e-09]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=63.5, Expect=7e-12]} {Celegans: WBGene00001133, eat-2, Neuronal acetylcholine receptor subunit eat-2, [Score=56.2, Expect=2e-09]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=56.2, Expect=1e-09]} {RNA1509_7752} {RNA1310_57458} {RNA815_42787}
89. MligTC455_24764 207 4.31 Mlig455_049092

Neo: Irradiation

Age: -

MCM9 0.978 - - - - 0.978 - Mlig455_049092 {REF} {Length: 5890} {TRANSSPLICED} {Pfam: MCM P-loop domain [PF00493.25, score=247.6]; MCM OB domain [PF17207.5, score=79.4]; MCM AAA-lid domain [PF17855.3, score=60.0]; Magnesium chelatase, subunit ChlI [PF01078.23, score=29.2]; AAA domain (dynein-related subfamily) [PF07728.16, score=27.5]} {Human: ENSG00000111877, MCM9, minichromosome maintenance 9 homologous recombination repair factor, [RH, Score=551, Expect=4e-172]} {Mouse: ENSMUSG00000058298, Mcm9, minichromosome maintenance 9 homologous recombination repair factor, [RH, Score=556, Expect=1e-172]} {Dmel: FBgn0014861, Mcm2, Minichromosome maintenance 2, [Score=265, Expect=1e-73]} {Celegans: WBGene00003154, mcm-2, Yeast MCM (Licensing factor) related, [Score=249, Expect=2e-68]} {Smed: dd_Smed_v6_18101_0_1, dd_Smed_v6_18101_0_1, [RH, Score=435, Expect=4e-136]} {RNA1509_37511, RNA1509_48203} {RNA1310_3712.1, RNA1509_48203} {RNA1509_48203, RNA815_6575.1}
90. MligTC455_45063 105 2.19 Mlig455_045829, Mlig455_045845, Mlig455_045862

Neo: -

Age: -

0.978 - - 0.978 - - -

Mlig455_045829 {REF} {Length: 4186} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=185.3]} {Celegans: WBGene00016064, acd-1, [Score=70.9, Expect=1e-12]} {Smed: dd_Smed_v6_19599_0_1, dd_Smed_v6_19599_0_1, [Score=120, Expect=1e-28]} {RNA1509_43949} {RNA1310_15301.1} {RNA815_26865}

Mlig455_045845 {REF} {Length: 3433} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=149.9]} {Celegans: WBGene00003174, mec-10, Degenerin mec-10, [Score=61.2, Expect=1e-09]} {Smed: dd_Smed_v6_23771_0_1, dd_Smed_v6_23771_0_1, [Score=101, Expect=1e-22]} {RNA1509_43949} {RNA1310_15301.1} {RNA815_26865}

Mlig455_045862 {REF} {Length: 3524} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=185.3]} {Celegans: WBGene00016064, acd-1, [Score=70.9, Expect=1e-12]} {Smed: dd_Smed_v6_19599_0_1, dd_Smed_v6_19599_0_1, [Score=120, Expect=1e-28]} {RNA1509_43949} {RNA1310_15301.1, RNA1509_43949} {RNA1509_43949, RNA815_26865}
91. MligTC455_46137 47 0.97 Mlig455_054506

Neo: -

Age: Down-Up-Down

PRKCZ 0.978 - - 0.978 - - - Mlig455_054506 {REF} {Length: 2255} {Pfam: PB1 domain [PF00564.26, score=24.9]} {Human: ENSG00000067606, PRKCZ, protein kinase C zeta, [Score=77.0, Expect=1e-14]} {Mouse: ENSMUSG00000029053, Prkcz, protein kinase C, zeta, [Score=77.4, Expect=4e-15]} {Smed: dd_Smed_v6_2110_0_2, dd_Smed_v6_2110_0_2, [Score=72.4, Expect=8e-14]} {RNA1310_76564} {RNA815_47904}
92. MligTC455_06158 9 0.18 Mlig455_032880

Neo: -

Age: -

0.977 - - 0.977 - - - Mlig455_032880 {REF} {Length: 2008} {Pfam: Glycine rich protein [PF12810.9, score=29.8]} {RNA1310_1880.1} {RNA815_25152}
93. MligTC455_10785 347 7.24 Mlig455_030825

Neo: -

Age: -

0.977 - - - - 0.977 - Mlig455_030825 {REF} {Length: 570} {Pfam: Essential protein Yae1, N terminal [PF09811.11, score=77.3]}
94. MligTC455_11635 21 0.43 Mlig455_033293

Neo: -

Age: -

0.977 - - 0.977 - - - Mlig455_033293 {REF} {Length: 2811} {RNA1509_56255} {RNA1310_121560} {RNA815_22311}
95. MligTC455_12782 51 1.07 Mlig455_012991

Neo: -

Age: -

0.977 - - - - 0.977 - Mlig455_012991 {REF} {Length: 1473} {TRANSSPLICED} {RNA1509_56473} {RNA1310_22716.1, RNA1509_56473} {RNA1509_56473, RNA815_10095.1}
96. MligTC455_15771 15 0.31 Mlig455_013616

Neo: -

Age: -

0.977 - - 0.977 - - - Mlig455_013616 {REF} {Length: 1678} {Pfam: Glycine rich protein [PF12810.9, score=28.8]} {RNA1509_48637} {RNA1310_55197} {RNA815_27869}
97. MligTC455_23855 18 0.37 Mlig455_009141

Neo: -

Age: -

0.977 - - 0.977 - - - Mlig455_009141 {REF} {Length: 1113} {RNA1310_49105} {RNA815_36286}
98. MligTC455_36762 10 0.21 Mlig455_057461

Neo: -

Age: -

0.977 - - 0.977 - - - Mlig455_057461 {REF} {Length: 1806} {Pfam: Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=24.8]} {Smed: dd_Smed_v6_38501_0_1, dd_Smed_v6_38501_0_1, [Score=155, Expect=6e-43]}
99. MligTC455_40619 159 3.32 Mlig455_016768

Neo: -

Age: Up-Up-Down

KIF1A 0.977 - - - - 0.977 - Mlig455_016768 {REF} {Length: 6294} {Pfam: Kinesin protein 1B [PF12423.10, score=36.5]; FHA domain [PF00498.28, score=31.0]; Kinesin-associated [PF16183.7, score=19.9]} {Human: ENSG00000130294, KIF1A, kinesin family member 1A, [Score=87.4, Expect=4e-17]; ENSG00000054523, KIF1B, kinesin family member 1B, [Score=85.9, Expect=1e-16]} {Mouse: ENSMUSG00000087236, Kif28, kinesin family member 28, [Score=212, Expect=5e-58]} {Dmel: FBgn0267002, unc-104, uncoordinated-104, [Score=74.7, Expect=2e-13]} {Celegans: WBGene00002218, klp-6, Kinesin-like protein, [Score=236, Expect=6e-67]} {Smed: dd_Smed_v6_20223_0_1, dd_Smed_v6_20223_0_1, [Score=512, Expect=3e-172]} {RNA1509_18998} {RNA1310_3422, RNA1509_18998} {RNA1509_18998, RNA815_1532}
100. MligTC455_43362 93 1.95 Mlig455_002148

Neo: -

Age: -

0.977 - - - - 0.977 - Mlig455_002148 {REF} {Length: 2843} {TRANSSPLICED} {Smed: dd_Smed_v6_9636_0_1, dd_Smed_v6_9636_0_1, [RH, Score=127, Expect=1e-30]} {RNA1509_37248} {RNA1310_12152.1} {RNA815_8090}

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