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Results for MligTC455_25690

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_25690 76 1.58 Mlig455_038215

Neo: -

Age: -

Region-enriched R4: 6.785/0.00109

ADAM10 Mlig455_038215 {REF} {Length: 6713} {Pfam: Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=90.5]; Metallo-peptidase family M12 [PF13688.8, score=75.5]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=58.2]; Disintegrin [PF00200.25, score=41.7]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=35.5]; Reprolysin family propeptide [PF01562.21, score=30.4]; Glycine rich protein family [PF07172.13, score=24.2]} {Human: ENSG00000137845, ADAM10, ADAM metallopeptidase domain 10, [Score=415, Expect=6e-132]} {Mouse: ENSMUSG00000054693, Adam10, a disintegrin and metallopeptidase domain 10, [Score=415, Expect=3e-132]} {Dmel: FBgn0259984, kuz, kuzbanian, [Score=370, Expect=7e-112]} {Celegans: WBGene00006324, sup-17, ADAM 10; SUPpressor, [Score=406, Expect=4e-127]} {Smed: dd_Smed_v6_2341_0_1, dd_Smed_v6_2341_0_1, [Score=464, Expect=2e-149]} {RNA1509_8331} {RNA1310_15245} {RNA815_3227.1}

Cumulative graph for MligTC455_25690

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -4.695 1.748 0.99988 1.00000
RegionR2 -2.351 1.748 0.96099 1.00000
RegionR3 -0.835 1.748 0.89430 1.00000
RegionR4 6.785 1.748 0.00006 0.00109
RegionR5 3.437 1.748 0.01422 0.07517
RegionR6 2.539 1.748 0.06818 0.48726
RegionR7 -2.744 1.748 1.00000 1.00000
RegionR8 -2.136 1.748 0.99978 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 2.58 1.748 0.99972 1.00000
RegenerationR2 1.546 1.748 0.12774 0.55201
RegenerationR3 1.141 1.748 0.38408 0.79239
RegenerationR4 -1.426 1.748 0.22075 0.66881
RegenerationR5 -0.174 1.748 0.80817 0.99083
RegenerationR6 -0.489 1.748 0.55777 0.84393
RegenerationBL 1.891 1.748 0.32603 0.69268
RegenerationTP 0.372 1.748 0.66577 0.99730


Genes with expression patterns similar to MligTC455_25690

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_25690 76 1.58 Mlig455_038215

Neo: -

Age: -

Region-enriched R4: 6.785/0.00109

ADAM10 4 - - 1.000 1.000 1.000 1.000 Mlig455_038215 {REF} {Length: 6713} {Pfam: Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=90.5]; Metallo-peptidase family M12 [PF13688.8, score=75.5]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=58.2]; Disintegrin [PF00200.25, score=41.7]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=35.5]; Reprolysin family propeptide [PF01562.21, score=30.4]; Glycine rich protein family [PF07172.13, score=24.2]} {Human: ENSG00000137845, ADAM10, ADAM metallopeptidase domain 10, [Score=415, Expect=6e-132]} {Mouse: ENSMUSG00000054693, Adam10, a disintegrin and metallopeptidase domain 10, [Score=415, Expect=3e-132]} {Dmel: FBgn0259984, kuz, kuzbanian, [Score=370, Expect=7e-112]} {Celegans: WBGene00006324, sup-17, ADAM 10; SUPpressor, [Score=406, Expect=4e-127]} {Smed: dd_Smed_v6_2341_0_1, dd_Smed_v6_2341_0_1, [Score=464, Expect=2e-149]} {RNA1509_8331} {RNA1310_15245} {RNA815_3227.1}
2. MligTC455_21135 143 2.97 Mlig455_015452

Neo: -

Age: -

KMT2C 1.8 - - - 0.953 - 0.847 Mlig455_015452 {REF} {Length: 5052} {TRANSSPLICED} {Pfam: SET domain [PF00856.30, score=62.5]; PHD-zinc-finger like domain [PF13832.8, score=31.0]; PHD-like zinc-binding domain [PF13771.8, score=23.7]; F/Y-rich N-terminus [PF05964.16, score=18.6]} {Human: ENSG00000055609, KMT2C, lysine methyltransferase 2C, [Score=211, Expect=8e-55]; ENSG00000167548, KMT2D, lysine methyltransferase 2D, [Score=204, Expect=4e-52]} {Mouse: ENSMUSG00000038056, Kmt2c, lysine (K)-specific methyltransferase 2C, [Score=211, Expect=1e-54]; ENSMUSG00000048154, Kmt2d, lysine (K)-specific methyltransferase 2D, [Score=204, Expect=2e-52]} {Dmel: FBgn0023518, trr, trithorax-related, [Score=186, Expect=5e-47]} {Celegans: WBGene00011729, set-16, Histone-lysine N-methyltransferase, [Score=148, Expect=1e-35]} {Smed: dd_Smed_v6_6838_0_1, dd_Smed_v6_6838_0_1, [Score=198, Expect=2e-51]} {RNA1509_12595} {RNA1310_1313.2} {RNA815_2378}
3. MligTC455_50879 110 2.28 Mlig455_043839, Mlig455_047411

Neo: -

Age: logFC(26M/2M)=0.792

NCK2 0.984 - - 0.984 - - -

Mlig455_043839 {REF} {Length: 3103} {TRANSSPLICED} {Pfam: SH3 domain [PF00018.30, score=136.1]; Variant SH3 domain [PF14604.8, score=119.6]; Variant SH3 domain [PF07653.19, score=87.6]; SH2 domain [PF00017.26, score=57.8]; Bacterial SH3 domain [PF08239.13, score=31.8]; SH3 domain [PF17902.3, score=31.6]} {Human: ENSG00000071051, NCK2, NCK adaptor protein 2, [RH, Score=250, Expect=2e-78]} {Mouse: ENSMUSG00000066877, Nck2, non-catalytic region of tyrosine kinase adaptor protein 2, [RH, Score=242, Expect=1e-75]; ENSMUSG00000032475, Nck1, non-catalytic region of tyrosine kinase adaptor protein 1, [RH, Score=237, Expect=6e-74]} {Dmel: FBgn0010583, dock, dreadlocks, [RH, Score=227, Expect=3e-68]} {Celegans: WBGene00006410, nck-1, NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family, [RH, Score=244, Expect=2e-76]} {Smed: dd_Smed_v6_4816_0_1, dd_Smed_v6_4816_0_1, [RH, Score=250, Expect=2e-76]} {RNA1509_27778} {RNA1310_13092.1} {RNA815_9153}

Mlig455_047411 {REF} {Length: 3141} {TRANSSPLICED} {Pfam: SH3 domain [PF00018.30, score=136.1]; Variant SH3 domain [PF14604.8, score=119.6]; Variant SH3 domain [PF07653.19, score=87.6]; SH2 domain [PF00017.26, score=57.8]; Bacterial SH3 domain [PF08239.13, score=31.8]; SH3 domain [PF17902.3, score=31.6]} {Human: ENSG00000071051, NCK2, NCK adaptor protein 2, [RH, Score=251, Expect=7e-79]; ENSG00000158092, NCK1, NCK adaptor protein 1, [RH, Score=242, Expect=1e-75]} {Mouse: ENSMUSG00000032475, Nck1, non-catalytic region of tyrosine kinase adaptor protein 1, [RH, Score=242, Expect=1e-75]; ENSMUSG00000066877, Nck2, non-catalytic region of tyrosine kinase adaptor protein 2, [RH, Score=242, Expect=1e-75]} {Dmel: FBgn0010583, dock, dreadlocks, [RH, Score=228, Expect=2e-68]} {Celegans: WBGene00006410, nck-1, NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family, [RH, Score=245, Expect=6e-77]} {Smed: dd_Smed_v6_4816_0_1, dd_Smed_v6_4816_0_1, [RH, Score=249, Expect=6e-76]} {RNA1509_27778} {RNA1310_13092.1} {RNA815_9153}
4. MligTC455_16559 61 1.26 Mlig455_050729

Neo: -

Age: -

Region-enriched R3: 4.650/0.00893

C9orf116 0.971 - - 0.971 - - - Mlig455_050729 {REF} {Length: 952} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4490) [PF14892.8, score=113.1]} {Human: ENSG00000160345, C9orf116, chromosome 9 open reading frame 116, [RH, Score=81.3, Expect=2e-20]} {Mouse: ENSMUSG00000026831, 1700007K13Rik, RIKEN cDNA 1700007K13 gene, [RH, Score=82.4, Expect=8e-21]} {Dmel: FBgn0083943, CG34107, [RH, Score=64.7, Expect=2e-14]} {Smed: dd_Smed_v6_49903_0_1, dd_Smed_v6_49903_0_1, [RH, Score=73.2, Expect=4e-17]} {RNA1509_36646} {RNA1310_50869, RNA1509_36646} {RNA1509_36646, RNA815_31506}
5. MligTC455_14466 57 1.19 Mlig455_049619

Neo: -

Age: -

0.969 - - 0.969 - - - Mlig455_049619 {REF} {Length: 711}
6. MligTC455_43392 90 1.88 Mlig455_055609

Neo: -

Age: -

Region-enriched R4: 3.592/0.03736

0.959 - - - - 0.959 - Mlig455_055609 {REF} {Length: 3000} {TRANSSPLICED} {Mouse: ENSMUSG00000002343, Armc6, armadillo repeat containing 6, [RH, Score=120, Expect=3e-29]} {Dmel: FBgn0034315, CG5721, [RH, Score=113, Expect=7e-27]} {Smed: dd_Smed_v6_1357_0_1, dd_Smed_v6_1357_0_1, [RH, Score=147, Expect=8e-39]} {RNA1509_31191} {RNA1310_17098.1} {RNA815_7466}
7. MligTC455_18643 397 8.28 Mlig455_002712

Neo: -

Age: Down-Up-Down

Region-enriched R4: 2.396/0.03057

MFSD13A 0.953 - - - 0.953 - - Mlig455_002712 {REF} {Length: 2631} {Pfam: MFS/sugar transport protein [PF13347.8, score=59.8]} {Human: ENSG00000138111, MFSD13A, major facilitator superfamily domain containing 13A, [RH, Score=325, Expect=2e-104]} {Mouse: ENSMUSG00000025227, Mfsd13a, major facilitator superfamily domain containing 13a, [RH, Score=343, Expect=8e-112]} {Celegans: WBGene00016174, C27H5.4, [Score=100, Expect=2e-22]} {RNA1509_42736, RNA1509_51069} {RNA1310_16644.1, RNA1509_51069} {RNA1509_51069, RNA815_6472.1}
8. MligTC455_15133 269 5.61 Mlig455_006453

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.922

Region-enriched R3: 2.595/0.01395

0.952 - - 0.952 - - - Mlig455_006453 {REF} {Length: 681} {RNA1509_17881} {RNA1310_58107, RNA1509_17881} {RNA1509_17881, RNA815_29431}
9. MligTC455_38433 28 0.57 Mlig455_018439

Neo: -

Age: Up-Down-Up

GLS2 0.952 - - 0.952 - - - Mlig455_018439 {REF} {Length: 3949} {Pfam: Glutaminase [PF04960.17, score=314.8]; EF-hand domain [PF17959.3, score=59.1]; Ankyrin repeats (3 copies) [PF12796.9, score=26.4]; Ankyrin repeats (many copies) [PF13637.8, score=26.2]} {Human: ENSG00000135423, GLS2, glutaminase 2, [Score=473, Expect=3e-157]; ENSG00000115419, GLS, glutaminase, [Score=467, Expect=3e-154]} {Mouse: ENSMUSG00000044005, Gls2, glutaminase 2 (liver, mitochondrial), [Score=471, Expect=5e-157]; ENSMUSG00000026103, Gls, glutaminase, [Score=468, Expect=7e-155]} {Dmel: FBgn0261625, GLS, Glutaminase, [Score=474, Expect=5e-157]} {Celegans: WBGene00008435, glna-2, Putative glutaminase 2, [Score=457, Expect=2e-151]} {Smed: dd_Smed_v6_15097_0_1, dd_Smed_v6_15097_0_1, [Score=385, Expect=3e-126]} {RNA1509_48964} {RNA1310_56872}
10. MligTC455_30268 108 2.25 Mlig455_026672

Neo: -

Age: -

0.951 - - - 0.951 - - Mlig455_026672 {REF} {Length: 4320} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=29.9]; Endonuclease-reverse transcriptase [PF14529.8, score=26.1]; PHD-finger [PF00628.31, score=24.9]} {RNA1509_5039} {RNA1310_554.1} {RNA815_3500.1}
11. MligTC455_32456 153 3.19 Mlig455_034353

Neo: -

Age: -

ELAVL3 0.95 - - 0.950 - - - Mlig455_034353 {REF} {Length: 5138} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=279.8]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=27.7]; Occluded RNA-recognition motif [PF16842.7, score=27.3]; Nup53/35/40-type RNA recognition motif [PF05172.15, score=23.3]} {Human: ENSG00000196361, ELAVL3, ELAV like RNA binding protein 3, [Score=191, Expect=7e-54]; ENSG00000162374, ELAVL4, ELAV like RNA binding protein 4, [Score=191, Expect=9e-54]; ENSG00000107105, ELAVL2, ELAV like RNA binding protein 2, [Score=188, Expect=9e-53]; ENSG00000066044, ELAVL1, ELAV like RNA binding protein 1, [Score=185, Expect=3e-52]} {Mouse: ENSMUSG00000003410, Elavl3, ELAV like RNA binding protein 3, [Score=192, Expect=3e-54]; ENSMUSG00000028546, Elavl4, ELAV like RNA binding protein 4, [Score=191, Expect=7e-54]; ENSMUSG00000008489, Elavl2, ELAV like RNA binding protein 1, [Score=188, Expect=7e-53]; ENSMUSG00000040028, Elavl1, ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R), [Score=187, Expect=3e-53]} {Dmel: FBgn0086675, fne, found in neurons, [Score=189, Expect=9e-54]} {Celegans: WBGene00001368, exc-7, [Score=120, Expect=1e-28]} {Smed: dd_Smed_v6_11311_0_2, dd_Smed_v6_11311_0_2, [Score=112, Expect=2e-26]} {RNA1509_13713} {RNA1310_8489, RNA1509_13713} {RNA1509_13713, RNA815_12096}

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