Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_26477 | 2173 | 45.28 | Mlig455_023324 | Neo: - Age: Up-Down-Down Region-enriched R3: 5.118/0.00000 Regeneration-upregulated R5: 4.994 Regeneration-enriched R5: 4.994 |
CCDC80 | Mlig455_023324 {REF} {Length: 24894} {Pfam: Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=24.1]} {Human: ENSG00000091986, CCDC80, coiled-coil domain containing 80, [Score=57.0, Expect=1e-06]; ENSG00000138759, FRAS1, Fraser extracellular matrix complex subunit 1, [Score=56.6, Expect=2e-06]; ENSG00000117983, MUC5B, mucin 5B, oligomeric mucus/gel-forming, [Score=56.2, Expect=3e-06]; ENSG00000188162, OTOG, otogelin, [Score=55.1, Expect=6e-06]; ENSG00000215182, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [Score=54.3, Expect=1e-05]; ENSG00000283158, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [Score=54.3, Expect=1e-05]} {Mouse: ENSMUSG00000048191, Muc6, mucin 6, gastric, [Score=86.3, Expect=2e-15]} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=59.3, Expect=8e-08]} {Smed: dd_Smed_v6_3185_0_1, dd_Smed_v6_3185_0_1, [RH, Score=259, Expect=1e-73]} {RNA1509_358, RNA1509_743} {RNA1310_29.1, RNA1509_358} {RNA1509_358, RNA815_53.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 1.205 | 5.571 | 0.40413 | 1.00000 | |
RegionR2 | 3.488 | 5.571 | 0.00002 | 0.00126 | |
RegionR3 | 5.118 | 5.571 | 0.00000 | 0.00000 | |
RegionR4 | -0.831 | 5.571 | 0.43236 | 0.76111 | |
RegionR5 | -2.351 | 5.571 | 0.01901 | 0.09342 | |
RegionR6 | -1.225 | 5.571 | 0.21271 | 0.79060 | |
RegionR7 | -2.843 | 5.571 | 0.04946 | 0.42805 | |
RegionR8 | -2.559 | 5.571 | 0.14800 | 0.70045 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 2.993 | 5.571 | 0.02967 | 0.62634 | |
RegenerationR2 | -0.063 | 5.571 | 0.93525 | 1.00000 | |
RegenerationR3 | 0.051 | 5.571 | 0.96719 | 1.00000 | |
RegenerationR4 | 1.259 | 5.571 | 0.21227 | 0.65986 | |
RegenerationR5 | 4.994 | 5.571 | 0.00000 | 0.00096 | Specific for R5: 4.994 |
RegenerationR6 | 2.444 | 5.571 | 0.01728 | 0.16245 | |
RegenerationBL | 3.432 | 5.571 | 0.00084 | 0.02032 | |
RegenerationTP | 4.627 | 5.571 | 0.00014 | 0.01503 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_26477 | 2173 | 45.28 | Mlig455_023324 | Neo: - Age: Up-Down-Down Region-enriched R3: 5.118/0.00000 Regeneration-upregulated R5: 4.994 Regeneration-enriched R5: 4.994 |
CCDC80 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_023324 {REF} {Length: 24894} {Pfam: Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=24.1]} {Human: ENSG00000091986, CCDC80, coiled-coil domain containing 80, [Score=57.0, Expect=1e-06]; ENSG00000138759, FRAS1, Fraser extracellular matrix complex subunit 1, [Score=56.6, Expect=2e-06]; ENSG00000117983, MUC5B, mucin 5B, oligomeric mucus/gel-forming, [Score=56.2, Expect=3e-06]; ENSG00000188162, OTOG, otogelin, [Score=55.1, Expect=6e-06]; ENSG00000215182, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [Score=54.3, Expect=1e-05]; ENSG00000283158, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [Score=54.3, Expect=1e-05]} {Mouse: ENSMUSG00000048191, Muc6, mucin 6, gastric, [Score=86.3, Expect=2e-15]} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=59.3, Expect=8e-08]} {Smed: dd_Smed_v6_3185_0_1, dd_Smed_v6_3185_0_1, [RH, Score=259, Expect=1e-73]} {RNA1509_358, RNA1509_743} {RNA1310_29.1, RNA1509_358} {RNA1509_358, RNA815_53.1} |
2. | MligTC455_26473 | 1080 | 22.49 | Mlig455_023245 | Neo: - Age: Up-Down-Down Region-enriched R3: 5.994/0.00000 |
4.723 | 0.894 | 0.986 | 0.879 | 0.993 | 0.971 | - | Mlig455_023245 {REF} {Length: 5587} {Mouse: ENSMUSG00000006014, Prg4, proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein), [Score=59.7, Expect=2e-08]} {RNA1509_3202} {RNA1310_2753} {RNA815_1083.1} | |
3. | MligTC455_22061 | 1034 | 21.54 | Mlig455_023681 | Neo: - Age: Down-Down-Up Region-specific R3: 6.421 Region-enriched R3: 6.675/0.00000 |
4.324 | 0.846 | 0.878 | 0.720 | 0.975 | 0.905 | - | Mlig455_023681 {REF} {Length: 594} {RNA1509_30789} {RNA1310_74956, RNA1509_30789} {RNA1509_30789, RNA815_42722.1} | |
4. | MligTC455_28799 | 3659 | 76.23 | Mlig455_022296 | Neo: - Age: Up-Down-Up Region-enriched R3: 6.552/0.00000 |
ADGRL2 | 3.534 | 0.764 | 0.938 | 0.875 | - | 0.957 | - | Mlig455_022296 {REF} {Length: 9753} {Pfam: Galactose binding lectin domain [PF02140.20, score=148.4]; F5/8 type C domain [PF00754.27, score=27.6]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [Score=72.0, Expect=2e-11]} {Mouse: ENSMUSG00000028184, Adgrl2, adhesion G protein-coupled receptor L2, [Score=72.4, Expect=1e-11]} {Dmel: FBgn0033313, Cirl, Calcium-independent receptor for alpha-latrotoxin, [RH, Score=81.3, Expect=1e-14]} {Celegans: WBGene00044201, H39E23.3, [Score=57.8, Expect=1e-07]} {Smed: dd_Smed_v6_71482_0_1, dd_Smed_v6_71482_0_1, [Score=52.4, Expect=8e-07]} {RNA1509_2008} {RNA1310_12405.1} {RNA815_4135} |
5. | MligTC455_28798 | 3882 | 80.87 | Mlig455_020050 | Neo: - Age: logFC(26M/2M)=0.496 Region-enriched R3: 6.324/0.00000 |
ADGRL2 | 3.446 | 0.824 | 0.907 | 0.749 | - | 0.966 | - | Mlig455_020050 {REF} {Length: 18353} {Pfam: Galactose binding lectin domain [PF02140.20, score=146.3]; F5/8 type C domain [PF00754.27, score=26.9]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [Score=65.5, Expect=3e-09]} {Mouse: ENSMUSG00000028184, Adgrl2, adhesion G protein-coupled receptor L2, [Score=65.5, Expect=2e-09]} {Dmel: FBgn0033313, Cirl, Calcium-independent receptor for alpha-latrotoxin, [RH, Score=75.1, Expect=2e-12]} {RNA1509_12210} {RNA1310_12405.1} {RNA815_4135} |
6. | MligTC455_37658 | 1892 | 39.42 | Mlig455_001025, Mlig455_064203, Mlig455_065673 | Neo: - Age: - Region-enriched R3: 5.362/0.00000 |
TECTA, ZAN | 2.667 | 0.803 | 0.965 | - | - | 0.899 | - | Mlig455_001025 {REF} {Length: 14015} {Pfam: von Willebrand factor type A domain [PF00092.30, score=106.5]; von Willebrand factor type A domain [PF13519.8, score=105.1]; von Willebrand factor type D domain [PF00094.27, score=103.2]; Calcium-binding EGF domain [PF07645.17, score=83.3]; Galactose binding lectin domain [PF02140.20, score=68.2]; C8 domain [PF08742.13, score=47.6]; von Willebrand factor type A domain [PF13768.8, score=46.5]; EGF domain [PF12947.9, score=40.8]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=34.2]; Fibronectin type II domain [PF00040.21, score=29.8]; Complement Clr-like EGF-like [PF12662.9, score=20.5]} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=179, Expect=9e-44]; ENSG00000109927, TECTA, tectorin alpha, [Score=178, Expect=2e-43]; ENSG00000281123, FCGBP, Fc fragment of IgG binding protein, [Score=176, Expect=9e-43]; ENSG00000275395, FCGBP, Fc fragment of IgG binding protein, [Score=171, Expect=1e-41]} {Mouse: ENSMUSG00000047730, Fcgbp, Fc fragment of IgG binding protein, [Score=184, Expect=2e-45]; ENSMUSG00000037705, Tecta, tectorin alpha, [Score=179, Expect=8e-44]} {Dmel: FBgn0053196, dpy, dumpy, [Score=141, Expect=1e-32]} {Celegans: WBGene00001403, fbl-1, Fibulin-1, [Score=128, Expect=2e-29]} {Smed: dd_Smed_v6_1748_0_1, dd_Smed_v6_1748_0_1, [RH, Score=530, Expect=1e-155]} {RNA1509_4373} {RNA1310_104.1} {RNA815_50} Mlig455_064203 {REF} {Length: 18445} {Pfam: von Willebrand factor type A domain [PF13519.8, score=150.3]; von Willebrand factor type A domain [PF00092.30, score=130.4]; von Willebrand factor type D domain [PF00094.27, score=103.4]; Calcium-binding EGF domain [PF07645.17, score=81.7]; Galactose binding lectin domain [PF02140.20, score=68.0]; von Willebrand factor type A domain [PF13768.8, score=55.6]; C8 domain [PF08742.13, score=47.3]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=34.0]; EGF domain [PF12947.9, score=32.4]; Fibronectin type II domain [PF00040.21, score=29.5]; Complement Clr-like EGF-like [PF12662.9, score=20.2]} {Human: ENSG00000109927, TECTA, tectorin alpha, [Score=181, Expect=4e-44]; ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=179, Expect=1e-43]; ENSG00000281123, FCGBP, Fc fragment of IgG binding protein, [Score=175, Expect=3e-42]} {Mouse: ENSMUSG00000047730, Fcgbp, Fc fragment of IgG binding protein, [Score=183, Expect=6e-45]; ENSMUSG00000037705, Tecta, tectorin alpha, [Score=181, Expect=1e-44]} {Dmel: FBgn0053196, dpy, dumpy, [Score=141, Expect=3e-32]} {Celegans: WBGene00001403, fbl-1, Fibulin-1, [Score=130, Expect=6e-30]} {Smed: dd_Smed_v6_1748_0_1, dd_Smed_v6_1748_0_1, [Score=525, Expect=7e-154]} {RNA1509_4373} {RNA1310_104.1} {RNA815_50} Mlig455_065673 {REF} {Length: 1867} {RNA1509_3700} {RNA1310_2063.1} {RNA815_470} |
7. | MligTC455_26475 | 653 | 13.6 | Mlig455_023246 | Neo: - Age: Up-Down-Down, logFC(26M/2M)=0.894 Region-enriched R3: 3.795/0.00169 |
1.958 | - | - | - | 0.992 | 0.966 | - | Mlig455_023246 {REF} {Length: 10042} {Dmel: FBgn0013733, shot, short stop, [Score=64.3, Expect=1e-09]} {Smed: dd_Smed_v6_8929_0_1, dd_Smed_v6_8929_0_1, [Score=57.0, Expect=7e-08]} {RNA1509_470} {RNA1310_29.1} {RNA815_622} | |
8. | MligTC455_26478 | 450 | 9.37 | Mlig455_023316 | Neo: - Age: Up-Down-Down Region-enriched R3: 5.218/0.00065 |
VWF | 1.888 | - | - | - | 0.973 | 0.915 | - | Mlig455_023316 {REF} {Length: 11924} {Pfam: von Willebrand factor type D domain [PF00094.27, score=316.7]; C8 domain [PF08742.13, score=132.2]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=97.3]; von Willebrand factor type C domain [PF00093.20, score=28.5]; Major Vault Protein repeat domain [PF01505.20, score=22.1]; EGF-like domain [PF07974.15, score=19.4]} {Human: ENSG00000110799, VWF, von Willebrand factor, [RH, Score=561, Expect=3e-161]; ENSG00000197558, SSPO, SCO-spondin, [RH, Score=553, Expect=4e-158]} {Mouse: ENSMUSG00000001930, Vwf, Von Willebrand factor, [RH, Score=584, Expect=6e-169]; ENSMUSG00000029797, Sspo, SCO-spondin, [RH, Score=555, Expect=8e-159]} {Dmel: FBgn0029167, Hml, Hemolectin, [RH, Score=513, Expect=3e-146]} {Celegans: WBGene00000168, apx-1, Anterior pharynx in excess protein 1, [Score=75.9, Expect=2e-13]} {Smed: dd_Smed_v6_17988_0_1, dd_Smed_v6_17988_0_1, [RH, Score=1132, Expect=0.0]} {RNA1509_12284, RNA1509_28666, RNA1509_743, RNA1509_7717} {RNA1310_76, RNA1509_12284, RNA1509_28666, RNA1509_7717} {RNA1509_12284, RNA1509_28666, RNA1509_7717, RNA815_53.1} |
9. | MligTC455_26474 | 257 | 5.36 | Mlig455_023312 | Neo: Irradiation Age: Up-Down-Up Region-enriched R3: 5.747/0.00000 |
OTOG | 1.88 | - | 0.971 | - | - | 0.909 | - | Mlig455_023312 {REF} {Length: 3545} {Pfam: Cystine-knot domain [PF00007.24, score=40.6]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=28.4]} {Human: ENSG00000188162, OTOG, otogelin, [Score=53.9, Expect=6e-07]} {Mouse: ENSMUSG00000048191, Muc6, mucin 6, gastric, [Score=50.4, Expect=4e-06]} {Smed: dd_Smed_v6_3185_0_1, dd_Smed_v6_3185_0_1, [Score=210, Expect=6e-62]} {RNA1509_42162} {RNA1310_2753} {RNA815_1083.1} |
10. | MligTC455_31334 | 1337 | 27.85 | Mlig455_015103, Mlig455_027178 | Neo: - Age: - Region-enriched R3: 6.375/0.00000 |
1.702 | 0.733 | - | - | - | 0.969 | - | Mlig455_015103 {REF} {Length: 1543} {RNA1509_29805} {RNA1310_55274.2} {RNA815_31503.2} Mlig455_027178 {REF} {Length: 1135} {RNA1509_29805} {RNA1310_55274.2} {RNA815_31503.2} |
|
11. | MligTC455_36569 | 19 | 0.39 | Mlig455_006953 | Neo: - Age: - |
0.976 | - | - | - | - | - | 0.976 | Mlig455_006953 {REF} {Length: 2428} {RNA1509_41400} {RNA1310_4515.1} {RNA815_3928} | |
12. | MligTC455_43301 | 1085 | 22.6 | Mlig455_013371 | Neo: - Age: - Region-enriched R3: 1.193/0.02029 |
COL15A1 | 0.957 | - | - | - | 0.957 | - | - | Mlig455_013371 {REF} {Length: 2507} {Pfam: Collagenase NC10 and Endostatin [PF06482.13, score=81.8]; Collagen triple helix repeat (20 copies) [PF01391.20, score=27.7]} {Human: ENSG00000204291, COL15A1, collagen type XV alpha 1 chain, [Score=80.5, Expect=3e-15]} {Mouse: ENSMUSG00000001435, Col18a1, collagen, type XVIII, alpha 1, [Score=78.2, Expect=1e-14]} {Dmel: FBgn0260660, Mp, Multiplexin, [Score=95.5, Expect=1e-20]} {Smed: dd_Smed_v6_6811_0_1, dd_Smed_v6_6811_0_1, [RH, Score=77.8, Expect=5e-15]} {RNA1509_20865, RNA1509_26354, RNA1509_36504, RNA1509_43871, RNA1509_47612} {RNA1310_8823.2, RNA1509_20865, RNA1509_26354, RNA1509_36504, RNA1509_43871, RNA1509_47612} {RNA1509_20865, RNA1509_26354, RNA1509_36504, RNA1509_43871, RNA1509_47612, RNA815_3275.1} |