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Results for MligTC455_26737

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_26737 88 1.83 Mlig455_029468

Neo: -

Age: -

PCSK5 Mlig455_029468 {REF} {Length: 3143} {Pfam: Subtilase family [PF00082.24, score=157.0]; Proprotein convertase P-domain [PF01483.22, score=70.5]; Peptidase S8 pro-domain [PF16470.7, score=40.4]} {Human: ENSG00000099139, PCSK5, proprotein convertase subtilisin/kexin type 5, [RH, Score=498, Expect=3e-168]} {Mouse: ENSMUSG00000030513, Pcsk6, proprotein convertase subtilisin/kexin type 6, [Score=498, Expect=4e-165]; ENSMUSG00000024713, Pcsk5, proprotein convertase subtilisin/kexin type 5, [Score=498, Expect=2e-165]; ENSMUSG00000030530, Furin, furin (paired basic amino acid cleaving enzyme), [Score=489, Expect=1e-163]} {Dmel: FBgn0004509, Fur1, Furin 1, [Score=488, Expect=2e-162]} {Celegans: WBGene00002232, kpc-1, Furin-like protease kpc-1, [Score=513, Expect=1e-174]} {Smed: dd_Smed_v6_10832_0_1, dd_Smed_v6_10832_0_1, [Score=529, Expect=0.0]} {RNA1509_27501} {RNA1310_8704.1} {RNA815_23019}

Cumulative graph for MligTC455_26737

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -6.132 1.678 0.15381 0.77084
RegionR2 0.74 1.678 0.53211 0.90333
RegionR3 0.999 1.678 0.30092 0.84263
RegionR4 -1.297 1.678 0.99458 1.00000
RegionR5 1.126 1.678 0.19673 0.48472
RegionR6 1.172 1.678 0.22966 0.81315
RegionR7 1.393 1.678 0.21549 0.83235
RegionR8 1.999 1.678 0.07964 0.53693

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.379 1.678 0.99998 1.00000
RegenerationR2 0.033 1.678 0.96213 1.00000
RegenerationR3 -0.609 1.678 0.46017 0.83763
RegenerationR4 0.815 1.678 0.39391 0.80973
RegenerationR5 -0.571 1.678 0.41435 0.80801
RegenerationR6 -1.346 1.678 0.15439 0.48050
RegenerationBL -5.477 1.678 0.01021 0.10224
RegenerationTP -0.972 1.678 0.36083 0.80097


Genes with expression patterns similar to MligTC455_26737

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_26737 88 1.83 Mlig455_029468

Neo: -

Age: -

PCSK5 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_029468 {REF} {Length: 3143} {Pfam: Subtilase family [PF00082.24, score=157.0]; Proprotein convertase P-domain [PF01483.22, score=70.5]; Peptidase S8 pro-domain [PF16470.7, score=40.4]} {Human: ENSG00000099139, PCSK5, proprotein convertase subtilisin/kexin type 5, [RH, Score=498, Expect=3e-168]} {Mouse: ENSMUSG00000030513, Pcsk6, proprotein convertase subtilisin/kexin type 6, [Score=498, Expect=4e-165]; ENSMUSG00000024713, Pcsk5, proprotein convertase subtilisin/kexin type 5, [Score=498, Expect=2e-165]; ENSMUSG00000030530, Furin, furin (paired basic amino acid cleaving enzyme), [Score=489, Expect=1e-163]} {Dmel: FBgn0004509, Fur1, Furin 1, [Score=488, Expect=2e-162]} {Celegans: WBGene00002232, kpc-1, Furin-like protease kpc-1, [Score=513, Expect=1e-174]} {Smed: dd_Smed_v6_10832_0_1, dd_Smed_v6_10832_0_1, [Score=529, Expect=0.0]} {RNA1509_27501} {RNA1310_8704.1} {RNA815_23019}
2. MligTC455_52779 340 7.07 Mlig455_056574

Neo: -

Age: Down-Up-Down

2.458 0.952 0.786 0.720 - - - Mlig455_056574 {REF} {Length: 1070} {TRANSSPLICED} {RNA1509_51911} {RNA1310_24820.2, RNA1509_51911} {RNA1509_51911, RNA815_14661}
3. MligTC455_19444 2615 54.48 Mlig455_002765, Mlig455_050252

Neo: Irradiation

Age: Down-Up-Down, logFC(26M/2M)=-0.567

2.428 0.954 0.732 - 0.742 - -

Mlig455_002765 {REF} {Length: 718} {RNA1509_22419} {RNA1310_5535, RNA1509_22419} {RNA1509_22419, RNA815_6435}

Mlig455_050252 {REF} {Length: 956} {RNA1509_22419} {RNA1310_5535} {RNA815_6435}
4. MligTC455_33795 252 5.26 Mlig455_060633

Neo: -

Age: -

Region-enriched R8: 3.037/0.04043

CNFN 1.847 0.955 0.892 - - - - Mlig455_060633 {REF} {Length: 1246} {Pfam: PLAC8 family [PF04749.19, score=60.7]} {Human: ENSG00000105427, CNFN, cornifelin, [RH, Score=70.9, Expect=2e-16]} {Mouse: ENSMUSG00000063651, Cnfn, cornifelin, [RH, Score=70.9, Expect=2e-16]} {Smed: dd_Smed_v6_3182_0_1, dd_Smed_v6_3182_0_1, [RH, Score=85.1, Expect=3e-22]} {RNA1509_9786} {RNA1310_42064} {RNA815_27081}
5. MligTC455_47348 2699 56.22 Mlig455_014227

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.429

Region-specific R8: 6.506

Region-enriched R8: 5.811/0.00000
Region-enriched R7: 3.945/0.00000

1.828 0.963 0.865 - - - - Mlig455_014227 {REF} {Length: 1491} {RNA1509_14722, RNA1509_30918} {RNA1310_65420, RNA1509_14722, RNA1509_30918} {RNA1509_14722, RNA1509_30918, RNA815_35136}
6. MligTC455_32418 32 0.67 Mlig455_013940

Neo: -

Age: -

NWD2 1.822 0.962 0.860 - - - - Mlig455_013940 {REF} {Length: 6828} {Pfam: NACHT domain [PF05729.14, score=43.6]; AAA ATPase domain [PF13191.8, score=39.0]; Domain of unknown function (DUF4062) [PF13271.8, score=38.9]; AAA domain [PF13401.8, score=20.6]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [RH, Score=468, Expect=2e-135]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [RH, Score=462, Expect=2e-133]} {Dmel: FBgn0038397, CG10185, [Score=555, Expect=7e-166]} {Celegans: WBGene00020254, T05C3.2, [Score=571, Expect=4e-171]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=323, Expect=4e-89]} {RNA1509_3054} {RNA1310_322} {RNA815_139.1}
7. MligTC455_45251 109 2.27 Mlig455_012833

Neo: -

Age: Down-Down-Up

1.809 0.963 0.846 - - - - Mlig455_012833 {REF} {Length: 2880} {RNA1509_8813} {RNA1310_16550} {RNA815_17676}
8. MligTC455_15043 1215 25.31 Mlig455_028582, Mlig455_028601, Mlig455_056913

Neo: -

Age: Down-Up-Down

Region-enriched R8: 8.125/0.00000
Region-enriched R7: 5.243/0.00010

AL928654.3, CRIP1 1.808 0.958 0.850 - - - -

Mlig455_028582 {REF} {Length: 547} {Pfam: LIM domain [PF00412.24, score=54.3]; DNA gyrase inhibitor YacG [PF03884.16, score=18.3]} {Human: ENSG00000213145, CRIP1, cysteine rich protein 1, [RH, Score=140, Expect=3e-45]; ENSG00000257341, AL928654.3, novel transcript, [RH, Score=140, Expect=3e-45]} {Mouse: ENSMUSG00000006360, Crip1, cysteine-rich protein 1 (intestinal), [RH, Score=139, Expect=2e-44]} {Dmel: FBgn0039055, Rassf, Ras association family member, [Score=99.4, Expect=5e-26]} {Celegans: WBGene00015216, valv-1, [Score=114, Expect=3e-35]} {Smed: dd_Smed_v6_373_0_1, dd_Smed_v6_373_0_1, [Score=54.3, Expect=1e-10]} {RNA1310_46877} {RNA815_34890}

Mlig455_028601 {REF} {Length: 1461} {Pfam: LIM domain [PF00412.24, score=56.4]} {Human: ENSG00000213145, CRIP1, cysteine rich protein 1, [RH, Score=124, Expect=5e-39]; ENSG00000257341, AL928654.3, novel transcript, [RH, Score=124, Expect=5e-39]} {Mouse: ENSMUSG00000006360, Crip1, cysteine-rich protein 1 (intestinal), [RH, Score=122, Expect=3e-38]} {Dmel: FBgn0039055, Rassf, Ras association family member, [RH, Score=94.0, Expect=3e-24]} {Celegans: WBGene00015216, valv-1, [RH, Score=101, Expect=2e-30]} {Smed: dd_Smed_v6_373_0_1, dd_Smed_v6_373_0_1, [Score=55.8, Expect=2e-11]} {RNA1509_42587} {RNA1310_58649} {RNA815_34890}

Mlig455_056913 {REF} {Length: 444} {Pfam: LIM domain [PF00412.24, score=34.9]} {Human: ENSG00000257341, AL928654.3, novel transcript, [Score=103, Expect=6e-30]; ENSG00000213145, CRIP1, cysteine rich protein 1, [Score=103, Expect=6e-30]} {Mouse: ENSMUSG00000006360, Crip1, cysteine-rich protein 1 (intestinal), [Score=103, Expect=1e-29]} {Dmel: FBgn0039055, Rassf, Ras association family member, [Score=77.4, Expect=9e-18]} {Celegans: WBGene00015216, valv-1, [Score=83.6, Expect=2e-22]} {RNA1310_46877} {RNA815_34890}
9. MligTC455_15042 369 7.7 Mlig455_005904

Neo: -

Age: Down-Up-Down

Region-specific R8: 8.223

Region-enriched R8: 8.355/0.00000
Region-enriched R7: 5.709/0.00000

CRIP1 1.807 0.960 0.847 - - - - Mlig455_005904 {REF} {Length: 675} {Pfam: LIM domain [PF00412.24, score=56.3]} {Human: ENSG00000213145, CRIP1, cysteine rich protein 1, [RH, Score=142, Expect=5e-46]; ENSG00000257341, AL928654.3, novel transcript, [RH, Score=142, Expect=5e-46]} {Mouse: ENSMUSG00000006360, Crip1, cysteine-rich protein 1 (intestinal), [RH, Score=141, Expect=4e-45]} {Dmel: FBgn0039055, Rassf, Ras association family member, [Score=102, Expect=7e-27]} {Celegans: WBGene00015216, valv-1, [Score=115, Expect=8e-36]} {Smed: dd_Smed_v6_373_0_1, dd_Smed_v6_373_0_1, [Score=57.0, Expect=9e-12]} {RNA1310_46877} {RNA815_34890}
10. MligTC455_29243 202 4.21 Mlig455_007367, Mlig455_066683

Neo: -

Age: -

1.793 0.965 0.828 - - - -

Mlig455_007367 {REF} {Length: 1750} {NoTransDecoderORF} {RNA1509_57939} {RNA1310_66625}

Mlig455_066683 {REF} {Length: 1758} {NoTransDecoderORF} {RNA1509_57939} {RNA1310_66625}
11. MligTC455_48636 341 7.11 Mlig455_011518, Mlig455_011596

Neo: -

Age: logFC(26M/2M)=-0.426

Region-enriched R8: 3.002/0.00945

ANK2 1.789 0.966 0.823 - - - -

Mlig455_011518 {REF} {Length: 3815} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=62.1]; Ankyrin repeats (many copies) [PF13637.8, score=60.6]; Ankyrin repeats (many copies) [PF13857.8, score=58.3]; Ankyrin repeat [PF00023.32, score=42.0]; Ankyrin repeat [PF13606.8, score=37.8]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=64.3, Expect=1e-09]; ENSG00000132466, ANKRD17, ankyrin repeat domain 17, [Score=63.5, Expect=2e-09]; ENSG00000131503, ANKHD1, ankyrin repeat and KH domain containing 1, [Score=61.2, Expect=9e-09]; ENSG00000135299, ANKRD6, ankyrin repeat domain 6, [Score=61.2, Expect=5e-10]} {Mouse: ENSMUSG00000040183, Ankrd6, ankyrin repeat domain 6, [Score=67.4, Expect=7e-11]; ENSMUSG00000055204, Ankrd17, ankyrin repeat domain 17, [Score=64.7, Expect=7e-10]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=63.9, Expect=1e-09]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=57.4, Expect=6e-08]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=83.2, Expect=5e-16]} {RNA1509_43444} {RNA1310_500} {RNA815_20307}

Mlig455_011596 {REF} {Length: 3523} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=61.9]; Ankyrin repeats (many copies) [PF13637.8, score=60.4]; Ankyrin repeats (many copies) [PF13857.8, score=58.1]; Ankyrin repeat [PF00023.32, score=41.6]; Ankyrin repeat [PF13606.8, score=37.6]; Ion transport protein [PF00520.33, score=25.5]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=64.3, Expect=1e-09]; ENSG00000132466, ANKRD17, ankyrin repeat domain 17, [Score=63.9, Expect=2e-09]; ENSG00000135299, ANKRD6, ankyrin repeat domain 6, [Score=61.2, Expect=4e-10]} {Mouse: ENSMUSG00000040183, Ankrd6, ankyrin repeat domain 6, [Score=67.8, Expect=6e-11]; ENSMUSG00000055204, Ankrd17, ankyrin repeat domain 17, [Score=64.7, Expect=7e-10]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=64.3, Expect=8e-10]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=61.6, Expect=3e-09]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=86.7, Expect=4e-17]} {RNA1509_43444} {RNA1310_500} {RNA815_20307}
12. MligTC455_20243 37509 781.44 Mlig455_033274

Neo: -

Age: Down-Down-Up

Region-enriched R8: 1.605/0.00415

1.787 0.952 0.835 - - - - Mlig455_033274 {REF} {Length: 928} {RNA1509_12742, RNA1509_15995, RNA1509_20075, RNA1509_433, RNA1509_53941, RNA1509_6373, RNA1509_6856, RNA1509_694} {RNA1310_78625, RNA1509_12742, RNA1509_15995, RNA1509_20075, RNA1509_433, RNA1509_53941, RNA1509_6373, RNA1509_6856, RNA1509_694} {RNA1509_12742, RNA1509_15995, RNA1509_20075, RNA1509_433, RNA1509_53941, RNA1509_6373, RNA1509_6856, RNA1509_694, RNA815_37938}
13. MligTC455_27348 14734 306.95 Mlig455_034670, Mlig455_034672

Neo: -

Age: Up-Down-Down

Region-enriched R8: 2.406/0.03361

ANK1 1.783 0.953 0.830 - - - -

Mlig455_034670 {REF} {Length: 12517} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=273.4]; Ankyrin repeat [PF00023.32, score=216.6]; Ankyrin repeats (many copies) [PF13637.8, score=210.5]; Ankyrin repeat [PF13606.8, score=179.8]; Ankyrin repeats (many copies) [PF13857.8, score=150.1]; Mab-21 protein [PF03281.16, score=22.4]; PEGA domain [PF08308.13, score=18.6]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=252, Expect=2e-68]; ENSG00000151150, ANK3, ankyrin 3, [Score=245, Expect=3e-66]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=246, Expect=1e-66]; ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=243, Expect=1e-65]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=234, Expect=4e-63]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=248, Expect=3e-67]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=229, Expect=2e-61]} {Smed: dd_Smed_v6_10835_0_1, dd_Smed_v6_10835_0_1, [Score=243, Expect=2e-67]} {RNA1509_25730} {RNA1310_2249.2} {RNA815_11470.1}

Mlig455_034672 {REF} {Length: 829} {RNA1509_40299, RNA1509_5063} {RNA1310_76724, RNA1509_40299} {RNA1509_40299, RNA815_2813.2}
14. MligTC455_51724 3127 65.15 Mlig455_039322

Neo: -

Age: Down-Up-Down

Region-specific R8: 8.152

Region-enriched R8: 7.173/0.00000
Region-enriched R7: 4.174/0.00000

1.779 0.957 0.822 - - - - Mlig455_039322 {REF} {Length: 1511} {Smed: dd_Smed_v6_23342_0_1, dd_Smed_v6_23342_0_1, [RH, Score=55.8, Expect=2e-11]} {RNA1509_23031, RNA1509_24414} {RNA1310_57559.1, RNA1509_23031, RNA1509_24414} {RNA1509_23031, RNA1509_24414, RNA815_17881.1}
15. MligTC455_53694 2501 52.09 Mlig455_003991

Neo: -

Age: Down-Up-Up

Region-enriched R8: 7.080/0.00000
Region-enriched R7: 4.536/0.00005

CAV1 1.764 0.953 0.811 - - - - Mlig455_003991 {REF} {Length: 3303} {TRANSSPLICED} {Pfam: Caveolin [PF01146.19, score=127.7]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=102, Expect=1e-27]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=103, Expect=4e-28]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=78.6, Expect=3e-18]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=146, Expect=5e-46]} {RNA1509_19152} {RNA1310_47545} {RNA815_23829}
16. MligTC455_53695 2490 51.88 Mlig455_004074

Neo: -

Age: -

Region-enriched R8: 7.100/0.00000
Region-enriched R7: 4.566/0.00002

CAV1 1.764 0.953 0.811 - - - - Mlig455_004074 {REF} {Length: 808} {Pfam: Caveolin [PF01146.19, score=127.7]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=102, Expect=1e-27]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=103, Expect=4e-28]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=78.6, Expect=3e-18]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=146, Expect=5e-46]} {RNA1509_19152} {RNA1310_47545, RNA1509_19152} {RNA1509_19152, RNA815_23829}
17. MligTC455_07421 19136 398.66 Mlig455_029662

Neo: -

Age: Down-Up-Up

Region-specific R8: 3.646

Region-enriched R8: 3.196/0.00000
Region-enriched R7: 1.280/0.00593

SLC25A24 1.761 0.963 0.798 - - - - Mlig455_029662 {REF} {Length: 528} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=52.9]; EF hand [PF13202.8, score=51.2]; EF-hand domain pair [PF13499.8, score=51.0]; EF-hand domain [PF13405.8, score=41.8]; EF-hand domain pair [PF13833.8, score=41.6]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=26.1]; Family of unknown function (DUF5766) [PF19070.2, score=19.0]} {Human: ENSG00000085491, SLC25A24, solute carrier family 25 member 24, [Score=48.9, Expect=5e-08]; ENSG00000284468, SLC25A24, solute carrier family 25 member 24, [Score=48.9, Expect=5e-08]; ENSG00000114854, TNNC1, troponin C1, slow skeletal and cardiac type, [Score=48.1, Expect=6e-08]} {Mouse: ENSMUSG00000091898, Tnnc1, troponin C, cardiac/slow skeletal, [Score=48.5, Expect=3e-08]; ENSMUSG00000057738, Sptan1, spectrin alpha, non-erythrocytic 1, [Score=46.2, Expect=4e-07]} {Dmel: FBgn0250789, alpha-Spec, alpha Spectrin, [Score=47.0, Expect=1e-07]} {Smed: dd_Smed_v6_11874_0_1, dd_Smed_v6_11874_0_1, [Score=45.4, Expect=3e-07]} {RNA1509_10992, RNA1509_2519, RNA1509_679} {RNA1310_66965, RNA1509_10992, RNA1509_2519, RNA1509_679} {RNA1509_10992, RNA1509_2519, RNA1509_679, RNA815_31569.1}
18. MligTC455_26862 280 5.84 Mlig455_014582

Neo: -

Age: -

1.734 0.960 - 0.774 - - - Mlig455_014582 {REF} {Length: 3135} {TRANSSPLICED} {RNA1509_33062} {RNA1310_8891.1} {RNA815_1626.1}
19. MligTC455_32862 65 1.36 Mlig455_028346

Neo: -

Age: -

TOR1AIP1 1.712 0.957 - - - - 0.755 Mlig455_028346 {REF} {Length: 2450} {TRANSSPLICED} {Pfam: Lamina-associated polypeptide 1C (LAP1C) [PF05609.14, score=30.5]} {Human: ENSG00000143337, TOR1AIP1, torsin 1A interacting protein 1, [RH, Score=53.1, Expect=5e-07]} {Mouse: ENSMUSG00000026466, Tor1aip1, torsin A interacting protein 1, [RH, Score=61.2, Expect=1e-09]} {RNA1509_57779} {RNA1310_32543, RNA1509_57779} {RNA1509_57779, RNA815_8954.1}
20. MligTC455_30750 2067 43.07 Mlig455_051133, Mlig455_063036

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.340

1.685 0.953 0.732 - - - -

Mlig455_051133 {REF} {Length: 1343} {Pfam: Methyltransferase FkbM domain [PF05050.14, score=18.9]} {RNA1509_7841} {RNA1310_50281} {RNA815_3607}

Mlig455_063036 {REF} {Length: 2534} {Smed: dd_Smed_v6_25359_0_1, dd_Smed_v6_25359_0_1, [Score=73.9, Expect=1e-14]} {RNA1509_31595, RNA1509_31688, RNA1509_7841} {RNA1310_29896, RNA1509_31595, RNA1509_31688, RNA1509_7841} {RNA1509_31595, RNA1509_31688, RNA1509_7841, RNA815_3607}
21. MligTC455_33794 948 19.75 Mlig455_060591

Neo: -

Age: logFC(26M/2M)=-0.355

Region-enriched R8: 2.325/0.02122

CNFN 1.685 0.961 0.724 - - - - Mlig455_060591 {REF} {Length: 1665} {Pfam: PLAC8 family [PF04749.19, score=60.7]} {Human: ENSG00000105427, CNFN, cornifelin, [RH, Score=70.9, Expect=2e-16]} {Mouse: ENSMUSG00000063651, Cnfn, cornifelin, [RH, Score=70.9, Expect=2e-16]} {Smed: dd_Smed_v6_3182_0_1, dd_Smed_v6_3182_0_1, [RH, Score=85.1, Expect=3e-22]} {RNA1509_35358, RNA1509_9786} {RNA1310_42064, RNA1509_35358, RNA1509_9786} {RNA1509_35358, RNA1509_9786, RNA815_27081}
22. MligTC455_51658 123 2.56 Mlig455_028791

Neo: -

Age: Down-Up-Down

0.975 0.975 - - - - - Mlig455_028791 {REF} {Length: 2943} {TRANSSPLICED} {Pfam: F-box-like [PF12937.9, score=22.8]} {RNA1509_58492} {RNA1310_6222.1, RNA1509_58492} {RNA1509_58492, RNA815_11096}
23. MligTC455_14565 555 11.56 Mlig455_025146

Neo: -

Age: -

0.973 0.973 - - - - - Mlig455_025146 {REF} {Length: 2733} {TRANSSPLICED} {RNA1509_11357} {RNA1310_10080.1, RNA1509_11357} {RNA1509_11357, RNA815_13917}
24. MligTC455_30048 173 3.61 Mlig455_016483

Neo: -

Age: -

0.97 0.970 - - - - - Mlig455_016483 {REF} {Length: 6299} {TRANSSPLICED} {Smed: dd_Smed_v6_7411_0_1, dd_Smed_v6_7411_0_1, [RH, Score=50.4, Expect=4e-07]} {RNA1509_14295, RNA1509_41923} {RNA1310_1691.1, RNA1509_41923} {RNA1509_41923, RNA815_549.1}
25. MligTC455_50024 354 7.37 Mlig455_003621, Mlig455_070701

Neo: -

Age: Down-Up-Down

ATF7IP 0.97 0.970 - - - - -

Mlig455_003621 {REF} {Length: 4513} {TRANSSPLICED} {Pfam: Fibronectin-III type domain [PF16794.7, score=92.7]} {Human: ENSG00000171681, ATF7IP, activating transcription factor 7 interacting protein, [RH, Score=103, Expect=8e-22]} {Mouse: ENSMUSG00000030213, Atf7ip, activating transcription factor 7 interacting protein, [RH, Score=101, Expect=2e-21]} {Dmel: FBgn0027499, wde, windei, [RH, Score=90.9, Expect=3e-18]} {Smed: dd_Smed_v6_9372_0_1, dd_Smed_v6_9372_0_1, [RH, Score=75.5, Expect=2e-14]} {RNA1509_10271, RNA1509_53701} {RNA1310_5928.1, RNA1509_53701} {RNA1509_53701, RNA815_4314.1}

Mlig455_070701 {REF} {Length: 4470} {TRANSSPLICED} {RNA1509_10271} {RNA1310_5928.1} {RNA815_4314.1}
26. MligTC455_26662 78 1.63 Mlig455_061366, Mlig455_061393

Neo: -

Age: logFC(26M/2M)=-0.528

PLEKHG7 0.969 0.969 - - - - -

Mlig455_061366 {REF} {Length: 4952} {Pfam: RhoGEF domain [PF00621.22, score=76.5]; Pleckstrin homology domain [PF16652.7, score=44.5]; Pleckstrin homology domain [PF15405.8, score=20.6]} {Human: ENSG00000187510, PLEKHG7, pleckstrin homology and RhoGEF domain containing G7, [Score=234, Expect=2e-64]} {Mouse: ENSMUSG00000039713, Plekhg5, pleckstrin homology domain containing, family G (with RhoGef domain) member 5, [Score=119, Expect=1e-26]} {Dmel: FBgn0261556, CG42674, [Score=101, Expect=4e-21]} {Celegans: WBGene00022391, Y95B8A.12, [RH, Score=313, Expect=8e-93]} {Smed: dd_Smed_v6_20050_0_1, dd_Smed_v6_20050_0_1, [RH, Score=660, Expect=0.0]} {RNA1509_30198} {RNA1310_1409.1, RNA1509_30198} {RNA1509_30198, RNA815_382}

Mlig455_061393 {REF} {Length: 4339} {Pfam: RhoGEF domain [PF00621.22, score=77.2]; Pleckstrin homology domain [PF16652.7, score=33.5]; Pleckstrin homology domain [PF15405.8, score=19.3]} {Human: ENSG00000187510, PLEKHG7, pleckstrin homology and RhoGEF domain containing G7, [Score=229, Expect=6e-63]} {Mouse: ENSMUSG00000039713, Plekhg5, pleckstrin homology domain containing, family G (with RhoGef domain) member 5, [Score=107, Expect=6e-23]} {Dmel: FBgn0261556, CG42674, [Score=94.4, Expect=4e-19]} {Celegans: WBGene00022391, Y95B8A.12, [RH, Score=310, Expect=8e-93]} {Smed: dd_Smed_v6_20050_0_1, dd_Smed_v6_20050_0_1, [Score=644, Expect=0.0]} {RNA1509_30198} {RNA1310_1409.1} {RNA815_382}
27. MligTC455_30611 129 2.68 Mlig455_031173

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.392

Region-enriched R8: 4.530/0.01124

ITPR1 0.967 0.967 - - - - - Mlig455_031173 {REF} {Length: 9349} {Pfam: RIH domain [PF01365.23, score=93.2]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=76.6]; RyR and IP3R Homology associated [PF08454.13, score=72.8]; MIR domain [PF02815.21, score=44.1]; Ion transport protein [PF00520.33, score=31.9]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=239, Expect=4e-62]; ENSG00000123104, ITPR2, inositol 1,4,5-trisphosphate receptor type 2, [Score=229, Expect=2e-59]} {Mouse: ENSMUSG00000042644, Itpr3, inositol 1,4,5-triphosphate receptor 3, [Score=241, Expect=7e-63]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=202, Expect=3e-51]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=174, Expect=7e-43]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1868, Expect=0.0]} {RNA1509_5518} {RNA1310_129.1} {RNA815_62.1}
28. MligTC455_19216 82 1.71 Mlig455_038007

Neo: Int S/G2/M

Age: -

0.966 0.966 - - - - - Mlig455_038007 {REF} {Length: 2594} {TRANSSPLICED} {RNA1509_48249} {RNA1310_31830} {RNA815_49860}
29. MligTC455_41193 242 5.03 Mlig455_021133

Neo: -

Age: Down-Up-Up

Region-enriched R8: 7.101/0.01716

0.965 0.965 - - - - - Mlig455_021133 {REF} {Length: 1148} {RNA1310_28844} {RNA815_36557}
30. MligTC455_27365 3903 81.32 Mlig455_008275

Neo: -

Age: -

Region-enriched R4: 3.124/0.00001
Region-enriched R8: 1.668/0.04043

0.964 0.964 - - - - - Mlig455_008275 {REF} {Length: 1620} {RNA1509_1252} {RNA1310_61787} {RNA815_19934.1}
31. MligTC455_38210 2373 49.43 Mlig455_037531, Mlig455_037572, Mlig455_037608

Neo: -

Age: logFC(26M/2M)=-0.177

RBPJ 0.964 0.964 - - - - -

Mlig455_037531 {REF} {Length: 2755} {TRANSSPLICED} {Pfam: LAG1, DNA binding [PF09271.13, score=158.6]; Beta-trefoil DNA-binding domain [PF09270.12, score=66.9]; TIG domain [PF20144.1, score=35.5]} {Human: ENSG00000168214, RBPJ, recombination signal binding protein for immunoglobulin kappa J region, [Score=429, Expect=5e-145]} {Mouse: ENSMUSG00000039191, Rbpj, recombination signal binding protein for immunoglobulin kappa J region, [Score=429, Expect=2e-145]} {Dmel: FBgn0004837, Su(H), Suppressor of Hairless, [Score=426, Expect=6e-143]} {Celegans: WBGene00002245, lag-1, DNA-binding protein LAG-1; Lag-1 protein; Lin-12 And Glp-1 phenotype, [Score=323, Expect=8e-103]} {Smed: dd_Smed_v6_6047_0_1, dd_Smed_v6_6047_0_1, [Score=352, Expect=1e-115]} {RNA1509_7384} {RNA1310_5800.1} {RNA815_9825}

Mlig455_037572 {REF} {Length: 3500} {Pfam: Beta-trefoil DNA-binding domain [PF09270.12, score=179.2]; TIG domain [PF20144.1, score=99.5]; LAG1, DNA binding [PF09271.13, score=80.9]} {Human: ENSG00000168214, RBPJ, recombination signal binding protein for immunoglobulin kappa J region, [Score=555, Expect=0.0]} {Mouse: ENSMUSG00000039191, Rbpj, recombination signal binding protein for immunoglobulin kappa J region, [Score=553, Expect=0.0]} {Dmel: FBgn0004837, Su(H), Suppressor of Hairless, [Score=549, Expect=0.0]} {Celegans: WBGene00002245, lag-1, DNA-binding protein LAG-1; Lag-1 protein; Lin-12 And Glp-1 phenotype, [Score=402, Expect=1e-131]} {Smed: dd_Smed_v6_6047_0_1, dd_Smed_v6_6047_0_1, [Score=534, Expect=0.0]} {RNA1509_7384} {RNA1310_5800.1} {RNA815_9825}

Mlig455_037608 {REF} {Length: 2966} {TRANSSPLICED} {Pfam: Beta-trefoil DNA-binding domain [PF09270.12, score=179.5]; LAG1, DNA binding [PF09271.13, score=158.1]; TIG domain [PF20144.1, score=99.8]} {Human: ENSG00000168214, RBPJ, recombination signal binding protein for immunoglobulin kappa J region, [RH, Score=640, Expect=0.0]} {Mouse: ENSMUSG00000039191, Rbpj, recombination signal binding protein for immunoglobulin kappa J region, [RH, Score=636, Expect=0.0]} {Dmel: FBgn0004837, Su(H), Suppressor of Hairless, [RH, Score=635, Expect=0.0]} {Celegans: WBGene00002245, lag-1, DNA-binding protein LAG-1; Lag-1 protein; Lin-12 And Glp-1 phenotype, [RH, Score=470, Expect=7e-159]} {Smed: dd_Smed_v6_6047_0_1, dd_Smed_v6_6047_0_1, [RH, Score=612, Expect=0.0]} {RNA1509_7384} {RNA1310_5800.1} {RNA815_9825}
32. MligTC455_46348 246 5.12 Mlig455_023022, Mlig455_023167

Neo: -

Age: -

ELOF1 0.964 0.964 - - - - -

Mlig455_023022 {REF} {Length: 1062} {TRANSSPLICED} {Pfam: Transcription elongation factor Elf1 like [PF05129.15, score=104.0]} {Human: ENSG00000130165, ELOF1, elongation factor 1 homolog, [RH, Score=102, Expect=2e-29]} {Mouse: ENSMUSG00000013822, Elof1, ELF1 homolog, elongation factor 1, [RH, Score=101, Expect=1e-29]} {Dmel: FBgn0063670, CG40228, [RH, Score=133, Expect=2e-42]} {Celegans: WBGene00013219, Y54G11A.11, Transcription elongation factor 1 homolog, [RH, Score=134, Expect=6e-43]} {Smed: dd_Smed_v6_3505_0_1, dd_Smed_v6_3505_0_1, [RH, Score=122, Expect=2e-38]} {RNA1509_9167} {RNA1310_32925} {RNA815_15186.1}

Mlig455_023167 {REF} {Length: 1061} {TRANSSPLICED} {Pfam: Transcription elongation factor Elf1 like [PF05129.15, score=104.0]} {Human: ENSG00000130165, ELOF1, elongation factor 1 homolog, [RH, Score=102, Expect=2e-29]} {Mouse: ENSMUSG00000013822, Elof1, ELF1 homolog, elongation factor 1, [RH, Score=101, Expect=1e-29]} {Dmel: FBgn0063670, CG40228, [RH, Score=133, Expect=2e-42]} {Celegans: WBGene00013219, Y54G11A.11, Transcription elongation factor 1 homolog, [RH, Score=134, Expect=6e-43]} {Smed: dd_Smed_v6_3505_0_1, dd_Smed_v6_3505_0_1, [RH, Score=122, Expect=2e-38]} {RNA1509_9167} {RNA1310_32925} {RNA815_15186.1}
33. MligTC455_06002 108 2.24 Mlig455_067469

Neo: -

Age: -

CHRNA10 0.963 0.963 - - - - - Mlig455_067469 {REF} {Length: 3906} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=181.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=66.5]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=198, Expect=2e-57]; ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=193, Expect=9e-56]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=192, Expect=7e-55]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=199, Expect=6e-58]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=196, Expect=1e-56]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=192, Expect=1e-54]} {Celegans: WBGene00000043, acr-3, Acetylcholine receptor subunit beta-type acr-3, [Score=195, Expect=2e-56]} {Smed: dd_Smed_v6_23922_0_1, dd_Smed_v6_23922_0_1, [Score=226, Expect=3e-67]} {RNA1509_21945} {RNA1310_29351} {RNA815_3782.1}
34. MligTC455_10674 457 9.51 Mlig455_033481

Neo: -

Age: Down-Up-Down

0.963 0.963 - - - - - Mlig455_033481 {REF} {Length: 2182} {Smed: dd_Smed_v6_5091_0_1, dd_Smed_v6_5091_0_1, [RH, Score=154, Expect=1e-45]} {RNA1509_8208} {RNA1310_11510} {RNA815_4269}
35. MligTC455_14730 218 4.55 Mlig455_031670

Neo: -

Age: -

Region-enriched R4: 2.798/0.04773

GLIPR2 0.963 0.963 - - - - - Mlig455_031670 {REF} {Length: 1709} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=60.8]} {Human: ENSG00000122694, GLIPR2, GLI pathogenesis related 2, [Score=98.2, Expect=3e-25]} {Mouse: ENSMUSG00000028480, Glipr2, GLI pathogenesis-related 2, [Score=94.4, Expect=6e-24]} {Dmel: FBgn0051482, CG31482, [Score=92.8, Expect=5e-23]} {Celegans: WBGene00008604, F09B9.5, [Score=72.4, Expect=1e-15]} {Smed: dd_Smed_v6_762_0_1, dd_Smed_v6_762_0_1, [Score=116, Expect=9e-32]} {RNA1509_3027} {RNA1310_34590.1} {RNA815_14111.1}
36. MligTC455_35010 516 10.75 Mlig455_054169

Neo: -

Age: logFC(26M/2M)=-0.545

Region-enriched R5: 1.964/0.00569

CALML5 0.963 0.963 - - - - - Mlig455_054169 {REF} {Length: 914} {TRANSSPLICED} {Pfam: EF hand [PF00036.34, score=51.8]; EF-hand domain pair [PF13499.8, score=50.0]; EF-hand domain [PF13405.8, score=42.7]; EF-hand domain pair [PF13833.8, score=41.2]; EF hand [PF13202.8, score=39.4]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.0]} {Human: ENSG00000178372, CALML5, calmodulin like 5, [Score=56.2, Expect=3e-10]} {Mouse: ENSMUSG00000005649, Cabp5, calcium binding protein 5, [Score=55.1, Expect=8e-10]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=48.5, Expect=1e-07]} {Celegans: WBGene00006861, cal-5, CALmodulin related genes, [Score=62.0, Expect=8e-13]} {Smed: dd_Smed_v6_11942_0_1, dd_Smed_v6_11942_0_1, [Score=50.4, Expect=2e-08]} {RNA1509_32665} {RNA1310_29494.2} {RNA815_16454.1}
37. MligTC455_52255 215 4.48 Mlig455_020595

Neo: -

Age: -

0.963 0.963 - - - - - Mlig455_020595 {REF} {Length: 2601} {Pfam: TIR domain [PF13676.8, score=69.5]; BTK motif [PF00779.21, score=29.8]; TIR domain [PF01582.22, score=24.8]} {Smed: dd_Smed_v6_4452_0_1, dd_Smed_v6_4452_0_1, [Score=70.9, Expect=1e-12]} {RNA1509_54137} {RNA1310_8917.1} {RNA815_7724}
38. MligTC455_43566 36 0.76 Mlig455_056590

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.289

0.961 0.961 - - - - - Mlig455_056590 {REF} {Length: 10047} {TRANSSPLICED} {Smed: dd_Smed_v6_5859_0_1, dd_Smed_v6_5859_0_1, [Score=93.2, Expect=3e-20]} {RNA1509_7758} {RNA1310_5822, RNA1509_7758} {RNA1509_7758, RNA815_2990}
39. MligTC455_53635 117 2.44 Mlig455_005517

Neo: -

Age: Down-Down-Up

0.961 0.961 - - - - - Mlig455_005517 {REF} {Length: 1492} {Pfam: Domain of unknown function (DUF4606) [PF15379.8, score=21.9]} {RNA1509_29719} {RNA1310_26435, RNA1509_29719} {RNA1509_29719, RNA815_10531.1}
40. MligTC455_43307 242 5.04 Mlig455_061239

Neo: -

Age: -

0.96 0.960 - - - - - Mlig455_061239 {REF} {Length: 792} {NoTransDecoderORF} {RNA1509_38062} {RNA1310_36873} {RNA815_8442.1}
41. MligTC455_19421 87 1.8 Mlig455_018319

Neo: -

Age: -

0.959 0.959 - - - - - Mlig455_018319 {REF} {Length: 93} {NoTransDecoderORF} {RNA1509_23588}
42. MligTC455_21753 67 1.39 Mlig455_023195, Mlig455_025831

Neo: -

Age: -

0.959 0.959 - - - - -

Mlig455_023195 {REF} {Length: 660} {NoTransDecoderORF} {RNA1310_73607.2} {RNA815_19357}

Mlig455_025831 {REF} {Length: 410} {NoTransDecoderORF} {RNA1310_98124} {RNA815_19357}
43. MligTC455_23250 77 1.6 Mlig455_007377

Neo: -

Age: logFC(26M/2M)=-0.358

ZNFX1 0.959 0.959 - - - - - Mlig455_007377 {REF} {Length: 8692} {Human: ENSG00000124201, ZNFX1, zinc finger NFX1-type containing 1, [Score=57.0, Expect=1e-07]} {Smed: dd_Smed_v6_10024_0_1, dd_Smed_v6_10024_0_1, [Score=58.9, Expect=7e-09]} {RNA1509_28858} {RNA1310_711, RNA1509_28858} {RNA1509_28858, RNA815_1324.1}
44. MligTC455_40780 107 2.22 Mlig455_000276, Mlig455_024108, Mlig455_035730, Mlig455_058355

Neo: -

Age: -

0.958 0.958 - - - - -

Mlig455_000276 {REF} {Length: 1350} {RNA1310_30070} {RNA815_59383}

Mlig455_024108 {REF} {Length: 1999} {RNA1310_30070} {RNA815_59383}

Mlig455_035730 {REF} {Length: 2143} {RNA1310_30070} {RNA815_59383}

Mlig455_058355 {REF} {Length: 1365} {RNA1310_30070} {RNA815_59383}
45. MligTC455_43572 61 1.26 Mlig455_037945

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.663

VCX3B 0.958 0.958 - - - - - Mlig455_037945 {REF} {Length: 2194} {Human: ENSG00000205642, VCX3B, variable charge X-linked 3B, [Score=54.7, Expect=8e-09]} {RNA1509_22457} {RNA1310_35286} {RNA815_20576}
46. MligTC455_47647 386 8.05 Mlig455_039025, Mlig455_039029

Neo: -

Age: Down-Up-Down

Region-enriched R8: 8.248/0.00000
Region-enriched R2: 6.877/0.00091
Region-enriched R7: 4.106/0.01478

0.958 0.958 - - - - -

Mlig455_039025 {REF} {Length: 996} {NoTransDecoderORF} {RNA1509_17584, RNA1509_53722, RNA1509_59811} {RNA1310_35546, RNA1509_17584, RNA1509_53722, RNA1509_59811} {RNA1509_17584, RNA1509_53722, RNA1509_59811, RNA815_23548}

Mlig455_039029 {REF} {Length: 557} {NoTransDecoderORF} {RNA1509_17584} {RNA1310_35546} {RNA815_23548}
47. MligTC455_20339 248 5.16 Mlig455_049193

Neo: -

Age: logFC(26M/2M)=0.976

Region-enriched R8: 3.824/0.00004

0.957 0.957 - - - - - Mlig455_049193 {REF} {Length: 1276} {TRANSSPLICED} {RNA1509_32364} {RNA1310_8246} {RNA815_10070.1}
48. MligTC455_27504 740 15.41 Mlig455_020062, Mlig455_040861, Mlig455_066484

Neo: -

Age: logFC(26M/2M)=-0.403

MAP3K4 0.957 0.957 - - - - -

Mlig455_020062 {REF} {Length: 3921} {Pfam: Protein kinase domain [PF00069.27, score=304.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=232.8]; Ankyrin repeats (3 copies) [PF12796.9, score=74.3]; Ankyrin repeats (many copies) [PF13637.8, score=57.7]; Fungal protein kinase [PF17667.3, score=52.3]; Ankyrin repeat [PF13606.8, score=45.1]; Ankyrin repeats (many copies) [PF13857.8, score=44.3]; Ankyrin repeat [PF00023.32, score=40.1]; ABC1 atypical kinase-like domain [PF03109.18, score=35.8]; Phosphotransferase enzyme family [PF01636.25, score=31.6]; Kinase-like [PF14531.8, score=24.3]; Ternary complex associated domain 9 [PF19974.1, score=23.0]; Seadornavirus VP7 [PF07387.13, score=21.7]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=128, Expect=2e-29]; ENSG00000095015, MAP3K1, mitogen-activated protein kinase kinase kinase 1, [Score=122, Expect=1e-27]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=124, Expect=3e-29]; ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=124, Expect=3e-28]; ENSMUSG00000021754, Map3k1, mitogen-activated protein kinase kinase kinase 1, [Score=122, Expect=1e-27]; ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=119, Expect=1e-26]} {Dmel: FBgn0024329, Mekk1, [Score=120, Expect=2e-27]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=107, Expect=1e-23]} {Smed: dd_Smed_v6_5138_0_2, dd_Smed_v6_5138_0_2, [Score=113, Expect=1e-25]} {RNA1509_27731} {RNA1310_10050} {RNA815_9449.1}

Mlig455_040861 {REF} {Length: 3678} {Pfam: Protein kinase domain [PF00069.27, score=305.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Ankyrin repeats (3 copies) [PF12796.9, score=74.0]; Ankyrin repeats (many copies) [PF13637.8, score=57.6]; Fungal protein kinase [PF17667.3, score=52.2]; Ankyrin repeats (many copies) [PF13857.8, score=47.2]; Ankyrin repeat [PF13606.8, score=45.9]; Ankyrin repeat [PF00023.32, score=41.3]; ABC1 atypical kinase-like domain [PF03109.18, score=35.2]; Phosphotransferase enzyme family [PF01636.25, score=30.9]; Kinase-like [PF14531.8, score=24.5]; Ternary complex associated domain 9 [PF19974.1, score=23.0]; Seadornavirus VP7 [PF07387.13, score=21.9]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=129, Expect=1e-29]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=124, Expect=3e-29]; ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=124, Expect=3e-28]; ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=119, Expect=9e-27]} {Dmel: FBgn0024329, Mekk1, [Score=121, Expect=2e-27]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=108, Expect=1e-23]} {Smed: dd_Smed_v6_4849_0_1, dd_Smed_v6_4849_0_1, [Score=114, Expect=1e-25]} {RNA1509_27731} {RNA1310_10050} {RNA815_9449.1}

Mlig455_066484 {REF} {Length: 2641} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=158.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=118.1]; Ankyrin repeats (3 copies) [PF12796.9, score=77.7]; Ankyrin repeats (many copies) [PF13637.8, score=59.1]; Ankyrin repeat [PF00023.32, score=50.0]; Ankyrin repeat [PF13606.8, score=49.5]; Ankyrin repeats (many copies) [PF13857.8, score=45.0]; Fungal protein kinase [PF17667.3, score=27.7]; ABC1 atypical kinase-like domain [PF03109.18, score=18.9]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=122, Expect=3e-28]; ENSG00000095015, MAP3K1, mitogen-activated protein kinase kinase kinase 1, [Score=119, Expect=3e-27]} {Mouse: ENSMUSG00000021754, Map3k1, mitogen-activated protein kinase kinase kinase 1, [Score=119, Expect=3e-27]; ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=119, Expect=3e-27]; ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=118, Expect=5e-27]} {Dmel: FBgn0024329, Mekk1, [Score=124, Expect=4e-29]} {Celegans: WBGene00006443, pak-2, Serine/threonine-protein kinase pak-2, [Score=100, Expect=3e-22]} {Smed: dd_Smed_v6_4849_0_1, dd_Smed_v6_4849_0_1, [Score=120, Expect=4e-28]} {RNA1509_27731, RNA1509_40242} {RNA1310_10050, RNA1509_40242} {RNA1509_40242, RNA815_9449.1}
49. MligTC455_33995 174 3.63 Mlig455_042151

Neo: -

Age: logFC(26M/2M)=-0.705

ANK1 0.956 0.956 - - - - - Mlig455_042151 {REF} {Length: 8174} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=414.4]; Ankyrin repeats (many copies) [PF13637.8, score=253.9]; Ankyrin repeats (many copies) [PF13857.8, score=156.9]; Ankyrin repeat [PF13606.8, score=149.6]; Ankyrin repeat [PF00023.32, score=87.1]; Family of unknown function (DUF6189) [PF19688.1, score=71.1]; 3,4-dihydroxy-2-butanone 4-phosphate synthase [PF00926.21, score=44.8]; Domain of unknown function (DUF6487) [PF20097.1, score=28.5]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=81.6, Expect=1e-14]} {Mouse: ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=71.6, Expect=9e-12]; ENSMUSG00000014498, Ankrd52, ankyrin repeat domain 52, [Score=68.2, Expect=9e-11]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=65.5, Expect=4e-10]} {RNA1509_28890} {RNA1310_16696.1, RNA1509_28890} {RNA1509_28890, RNA815_12859.1}
50. MligTC455_51929 115 2.39 Mlig455_012874

Neo: -

Age: -

Region-enriched R8: 4.701/0.00006

0.954 0.954 - - - - - Mlig455_012874 {REF} {Length: 1913} {RNA1310_82792}
51. MligTC455_30436 247 5.16 Mlig455_005917, Mlig455_007902, Mlig455_028139

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.855

0.953 0.953 - - - - -

Mlig455_005917 {REF} {Length: 1826} {RNA1509_50227} {RNA1310_7741.2} {RNA815_2064.1}

Mlig455_007902 {REF} {Length: 6338} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=29.0]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=27.9]} {RNA1509_25737} {RNA1310_2048} {RNA815_551.1}

Mlig455_028139 {REF} {Length: 2097} {RNA1509_50227} {RNA1310_7741.2} {RNA815_2064.1}
52. MligTC455_40245 125 2.61 Mlig455_045020

Neo: -

Age: -

Region-enriched R8: 2.724/0.00842

0.953 0.953 - - - - - Mlig455_045020 {REF} {Length: 4797} {RNA1509_7608} {RNA1310_23716} {RNA815_45025.1}
53. MligTC455_19195 96 2 Mlig455_006487

Neo: -

Age: Up-Down-Down

NIPSNAP3A 0.952 0.952 - - - - - Mlig455_006487 {REF} {Length: 2920} {tRNA: Leu(AAG),pseudo, score=21.7} {Pfam: NIPSNAP [PF07978.15, score=74.8]} {Human: ENSG00000136783, NIPSNAP3A, nipsnap homolog 3A, [RH, Score=59.7, Expect=2e-10]} {Mouse: ENSMUSG00000015242, Nipsnap3a, nipsnap homolog 3A, [RH, Score=54.3, Expect=1e-08]} {RNA1509_39070, RNA1509_43812} {RNA1310_35631, RNA1509_43812} {RNA1509_43812, RNA815_21493}
54. MligTC455_22482 55 1.14 Mlig455_019819

Neo: -

Age: -

0.952 0.952 - - - - - Mlig455_019819 {REF} {Length: 701} {NoTransDecoderORF} {RNA1310_85829.1} {RNA815_39613}
55. MligTC455_28538 214 4.46 Mlig455_035621

Neo: -

Age: Down-Up-Down

SEC14L1 0.952 - 0.952 - - - - Mlig455_035621 {REF} {Length: 3312} {Pfam: CRAL/TRIO domain [PF00650.22, score=71.7]; CRAL/TRIO, N-terminal domain [PF03765.17, score=29.7]} {Human: ENSG00000129657, SEC14L1, SEC14 like lipid binding 1, [Score=59.7, Expect=3e-09]} {Mouse: ENSMUSG00000020823, Sec14l1, SEC14-like lipid binding 1, [Score=59.3, Expect=3e-09]} {Dmel: FBgn0031814, retm, real-time, [Score=60.8, Expect=6e-10]} {Celegans: WBGene00011962, T23G5.2, CRAL-TRIO domain-containing protein T23G5.2, [Score=59.3, Expect=2e-09]} {Smed: dd_Smed_v6_1619_0_1, dd_Smed_v6_1619_0_1, [Score=261, Expect=1e-85]} {RNA1509_15886} {RNA1310_19297} {RNA815_8981}
56. MligTC455_30779 140 2.92 Mlig455_061630

Neo: -

Age: -

LRIG2 0.952 0.952 - - - - - Mlig455_061630 {REF} {Length: 6435} {Pfam: Leucine rich repeat [PF13855.8, score=97.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=39.2]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=37.9]} {Human: ENSG00000198799, LRIG2, leucine rich repeats and immunoglobulin like domains 2, [Score=57.4, Expect=2e-07]; ENSG00000255690, TRIL, TLR4 interactor with leucine rich repeats, [Score=55.1, Expect=9e-07]} {Mouse: ENSMUSG00000043496, Tril, TLR4 interactor with leucine-rich repeats, [Score=59.7, Expect=3e-08]} {Dmel: FBgn0004364, 18w, 18 wheeler, [Score=77.0, Expect=1e-13]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=75.9, Expect=2e-13]} {RNA1509_37294} {RNA1310_1523.2} {RNA815_1519}
57. MligTC455_18154 49 1.02 Mlig455_007613, Mlig455_020845

Neo: -

Age: -

0.951 0.951 - - - - -

Mlig455_007613 {REF} {Length: 600} {NoTransDecoderORF} {RNA1509_57131} {RNA1310_79039} {RNA815_36018}

Mlig455_020845 {REF} {Length: 2208} {Smed: dd_Smed_v6_91651_0_1, dd_Smed_v6_91651_0_1, [Score=48.9, Expect=7e-08]} {RNA1509_46103} {RNA1310_6410.2} {RNA815_31889}
58. MligTC455_35684 154 3.21 Mlig455_038829, Mlig455_038837, Mlig455_038838, Mlig455_038917

Neo: -

Age: Down-Down-Up

0.951 0.951 - - - - -

Mlig455_038829 {REF} {Length: 2614} {TRANSSPLICED} {RNA1509_23775} {RNA1310_13318} {RNA815_5748.1}

Mlig455_038837 {REF} {Length: 2042} {TRANSSPLICED} {RNA1509_23775} {RNA1310_13318} {RNA815_5748.1}

Mlig455_038838 {REF} {Length: 2563} {RNA1509_23775} {RNA1310_6695.1} {RNA815_5748.1}

Mlig455_038917 {REF} {Length: 2375} {TRANSSPLICED} {RNA1509_23775} {RNA1310_6695.2} {RNA815_5748.1}
59. MligTC455_43571 239 4.99 Mlig455_037843

Neo: -

Age: Up-Down-Down

0.951 0.951 - - - - - Mlig455_037843 {REF} {Length: 2732} {RNA1509_10285, RNA1509_47003} {RNA1310_32269, RNA1509_10285} {RNA1509_10285, RNA815_20576}
60. MligTC455_16222 431 8.99 Mlig455_033888, Mlig455_054116

Neo: -

Age: logFC(26M/2M)=0.990

Region-enriched R8: 3.408/0.00045
Region-enriched R7: 2.502/0.03357

0.95 0.950 - - - - -

Mlig455_033888 {REF} {Length: 1217} {RNA1310_29964} {RNA815_15923}

Mlig455_054116 {REF} {Length: 1404} {RNA1310_29964} {RNA815_15923}
61. MligTC455_21789 52 1.07 Mlig455_032584

Neo: -

Age: -

0.95 - 0.950 - - - - Mlig455_032584 {REF} {Length: 1578} {Pfam: Integrase zinc binding domain [PF17921.3, score=54.9]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=34.1]; Integrase core domain [PF00665.28, score=29.0]} {Smed: dd_Smed_v6_1574_6_73, dd_Smed_v6_1574_6_73, [Score=124, Expect=8e-31]} {RNA1509_29748} {RNA1310_1140.1} {RNA815_993.1}
62. MligTC455_26159 40212 837.74 Mlig455_020142, Mlig455_045024

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.997

0.95 0.950 - - - - -

Mlig455_020142 {REF} {Length: 927} {RNA1509_9299} {RNA1310_41517.1} {RNA815_16981}

Mlig455_045024 {REF} {Length: 949} {RNA1509_18818, RNA1509_2004, RNA1509_51734, RNA1509_9299} {RNA1310_41517.1, RNA1509_18818, RNA1509_2004, RNA1509_51734, RNA1509_9299} {RNA1509_18818, RNA1509_2004, RNA1509_51734, RNA1509_9299, RNA815_16981}
63. MligTC455_27627 225 4.69 Mlig455_065807

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.382

HEYL 0.95 0.950 - - - - - Mlig455_065807 {REF} {Length: 1800} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=45.1]; Hairy Orange [PF07527.15, score=20.8]} {Human: ENSG00000163909, HEYL, hes related family bHLH transcription factor with YRPW motif-like, [Score=85.9, Expect=2e-18]; ENSG00000135547, HEY2, hes related family bHLH transcription factor with YRPW motif 2, [Score=85.5, Expect=2e-18]} {Mouse: ENSMUSG00000019789, Hey2, hairy/enhancer-of-split related with YRPW motif 2, [Score=86.3, Expect=2e-18]; ENSMUSG00000032744, Heyl, hairy/enhancer-of-split related with YRPW motif-like, [Score=85.5, Expect=2e-18]} {Dmel: FBgn0259938, cwo, clockwork orange, [RH, Score=84.0, Expect=2e-17]} {Smed: dd_Smed_v6_22479_0_1, dd_Smed_v6_22479_0_1, [Score=70.9, Expect=9e-14]} {RNA1509_35089} {RNA1310_373, RNA1509_35089} {RNA1509_35089, RNA815_5586}
64. MligTC455_44081 148 3.09 Mlig455_061562

Neo: -

Age: -

Region-enriched R8: 3.788/0.01668

CASP3 0.95 0.950 - - - - - Mlig455_061562 {REF} {Length: 3978} {Pfam: Caspase domain [PF00656.24, score=73.6]; Histone H1-like nucleoprotein HC2 [PF07382.13, score=19.4]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=77.8, Expect=7e-15]} {Mouse: ENSMUSG00000031628, Casp3, caspase 3, [Score=70.5, Expect=1e-12]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=56.6, Expect=3e-08]} {Smed: dd_Smed_v6_3121_1_1, dd_Smed_v6_3121_1_1, [Score=66.6, Expect=1e-11]} {RNA1509_42576} {RNA1310_4183} {RNA815_3197.1}

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