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Results for MligTC455_26964

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_26964 11038 229.96 Mlig455_042220

Neo: Germline

Age: -

P4HB Mlig455_042220 {REF} {Length: 3004} {Pfam: Thioredoxin-like domain [PF13848.8, score=53.4]; ERp29, N-terminal domain [PF07912.15, score=27.6]; Thioredoxin [PF00085.22, score=25.0]} {Human: ENSG00000185624, P4HB, prolyl 4-hydroxylase subunit beta, [Score=177, Expect=1e-55]} {Mouse: ENSMUSG00000025130, P4hb, prolyl 4-hydroxylase, beta polypeptide, [Score=176, Expect=4e-53]} {Dmel: FBgn0014002, Pdi, Protein disulfide isomerase, [Score=128, Expect=3e-35]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [Score=184, Expect=6e-57]} {Smed: dd_Smed_v6_250_0_1, dd_Smed_v6_250_0_1, [Score=162, Expect=2e-48]} {RNA1509_1575} {RNA1310_2450.1} {RNA815_1453.1}

Cumulative graph for MligTC455_26964

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.288 7.963 0.39682 1.00000
RegionR2 -0.999 7.963 0.00008 0.00328
RegionR3 0.09 7.963 0.66121 1.00000
RegionR4 0.25 7.963 0.28485 0.59395
RegionR5 0.374 7.963 0.05596 0.20301
RegionR6 0.238 7.963 0.24374 0.82897
RegionR7 0.78 7.963 0.00008 0.00490
RegionR8 -0.445 7.963 0.08182 0.54371

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.987 7.963 0.03872 0.65992
RegenerationR2 -0.056 7.963 0.83129 0.99833
RegenerationR3 -0.229 7.963 0.39061 0.79638
RegenerationR4 -0.248 7.963 0.36610 0.79090
RegenerationR5 -0.32 7.963 0.21961 0.65412
RegenerationR6 -0.384 7.963 0.14435 0.46559
RegenerationBL -0.602 7.963 0.01462 0.12643
RegenerationTP -0.741 7.963 0.00541 0.12341


Genes with expression patterns similar to MligTC455_26964

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_26964 11038 229.96 Mlig455_042220

Neo: Germline

Age: -

P4HB 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_042220 {REF} {Length: 3004} {Pfam: Thioredoxin-like domain [PF13848.8, score=53.4]; ERp29, N-terminal domain [PF07912.15, score=27.6]; Thioredoxin [PF00085.22, score=25.0]} {Human: ENSG00000185624, P4HB, prolyl 4-hydroxylase subunit beta, [Score=177, Expect=1e-55]} {Mouse: ENSMUSG00000025130, P4hb, prolyl 4-hydroxylase, beta polypeptide, [Score=176, Expect=4e-53]} {Dmel: FBgn0014002, Pdi, Protein disulfide isomerase, [Score=128, Expect=3e-35]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [Score=184, Expect=6e-57]} {Smed: dd_Smed_v6_250_0_1, dd_Smed_v6_250_0_1, [Score=162, Expect=2e-48]} {RNA1509_1575} {RNA1310_2450.1} {RNA815_1453.1}
2. MligTC455_26965 32675 680.72 Mlig455_018994, Mlig455_055709

Neo: Germline

Age: logFC(26M/2M)=0.206

P4HB 5.283 0.810 0.904 0.840 0.954 0.905 0.870

Mlig455_018994 {REF} {Length: 3271} {Pfam: Thioredoxin [PF00085.22, score=208.2]; Thioredoxin-like domain [PF13848.8, score=151.5]; Thioredoxin-like domain [PF13098.8, score=58.6]; Calsequestrin [PF01216.19, score=52.1]; OST3 / OST6 family, transporter family [PF04756.15, score=45.9]; Thioredoxin-like [PF13905.8, score=43.3]; ERp29, N-terminal domain [PF07912.15, score=42.6]; Thioredoxin-like [PF13899.8, score=42.6]; AhpC/TSA family [PF00578.23, score=35.2]; Redoxin [PF08534.12, score=31.1]; F plasmid transfer operon protein [PF13728.8, score=23.3]} {Human: ENSG00000185624, P4HB, prolyl 4-hydroxylase subunit beta, [RH, Score=572, Expect=0.0]} {Mouse: ENSMUSG00000025130, P4hb, prolyl 4-hydroxylase, beta polypeptide, [RH, Score=563, Expect=0.0]} {Dmel: FBgn0014002, Pdi, Protein disulfide isomerase, [RH, Score=510, Expect=3e-178]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [RH, Score=565, Expect=0.0]} {Smed: dd_Smed_v6_250_0_1, dd_Smed_v6_250_0_1, [RH, Score=578, Expect=0.0]} {RNA1509_1575} {RNA1310_2450.1} {RNA815_1453.1}

Mlig455_055709 {REF} {Length: 3265} {Pfam: Thioredoxin [PF00085.22, score=208.2]; Thioredoxin-like domain [PF13848.8, score=151.5]; Thioredoxin-like domain [PF13098.8, score=58.6]; Calsequestrin [PF01216.19, score=52.1]; OST3 / OST6 family, transporter family [PF04756.15, score=45.9]; Thioredoxin-like [PF13905.8, score=43.3]; ERp29, N-terminal domain [PF07912.15, score=42.6]; Thioredoxin-like [PF13899.8, score=42.6]; AhpC/TSA family [PF00578.23, score=35.2]; Redoxin [PF08534.12, score=31.1]; F plasmid transfer operon protein [PF13728.8, score=23.3]} {Human: ENSG00000185624, P4HB, prolyl 4-hydroxylase subunit beta, [RH, Score=572, Expect=0.0]} {Mouse: ENSMUSG00000025130, P4hb, prolyl 4-hydroxylase, beta polypeptide, [RH, Score=563, Expect=0.0]} {Dmel: FBgn0014002, Pdi, Protein disulfide isomerase, [RH, Score=510, Expect=3e-178]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [RH, Score=565, Expect=0.0]} {Smed: dd_Smed_v6_250_0_1, dd_Smed_v6_250_0_1, [RH, Score=578, Expect=0.0]} {RNA1509_1575, RNA1509_70} {RNA1310_2450.1, RNA1509_1575, RNA1509_70} {RNA1509_1575, RNA1509_70, RNA815_1453.1}
3. MligTC455_31826 3263 67.98 Mlig455_047238

Neo: -

Age: logFC(26M/2M)=0.279

Region-enriched R3: 1.778/0.00195
Region-enriched R4: 1.661/0.00801
Region-enriched R5: 1.362/0.01219

CTDSP1 0.968 - - - - 0.968 - Mlig455_047238 {REF} {Length: 3089} {Pfam: NLI interacting factor-like phosphatase [PF03031.20, score=72.1]; VDE lipocalin domain [PF07137.13, score=58.0]} {Human: ENSG00000144579, CTDSP1, CTD small phosphatase 1, [Score=128, Expect=9e-33]} {Mouse: ENSMUSG00000026176, Ctdsp1, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1, [Score=127, Expect=7e-33]} {Dmel: FBgn0036556, CG5830, [Score=120, Expect=1e-29]} {Celegans: WBGene00007054, scpl-1, CTD small phosphatase-like protein 1, [Score=110, Expect=7e-27]} {Smed: dd_Smed_v6_8196_0_1, dd_Smed_v6_8196_0_1, [Score=135, Expect=3e-33]} {RNA1509_13014} {RNA1310_14334.1} {RNA815_7820}
4. MligTC455_23247 4480 93.33 Mlig455_008739, Mlig455_008755

Neo: Neoblast

Age: Down-Up-Up

Region-enriched R4: 1.709/0.00000
Region-enriched R5: 1.284/0.00000

Regeneration-upregulated BL: 1.449

Regeneration-enriched BL: 1.449

ELOF1 0.961 - - - 0.961 - -

Mlig455_008739 {REF} {Length: 720} {TRANSSPLICED} {Pfam: Transcription elongation factor Elf1 like [PF05129.15, score=104.1]} {Human: ENSG00000130165, ELOF1, elongation factor 1 homolog, [RH, Score=107, Expect=1e-31]} {Mouse: ENSMUSG00000013822, Elof1, ELF1 homolog, elongation factor 1, [RH, Score=106, Expect=1e-31]} {Dmel: FBgn0063670, CG40228, [RH, Score=139, Expect=7e-45]} {Celegans: WBGene00013219, Y54G11A.11, Transcription elongation factor 1 homolog, [RH, Score=140, Expect=1e-45]} {Smed: dd_Smed_v6_3505_0_1, dd_Smed_v6_3505_0_1, [RH, Score=122, Expect=2e-38]} {RNA1509_9049} {RNA1310_49008} {RNA815_24658}

Mlig455_008755 {REF} {Length: 720} {TRANSSPLICED} {Pfam: Transcription elongation factor Elf1 like [PF05129.15, score=104.1]} {Human: ENSG00000130165, ELOF1, elongation factor 1 homolog, [RH, Score=107, Expect=1e-31]} {Mouse: ENSMUSG00000013822, Elof1, ELF1 homolog, elongation factor 1, [RH, Score=106, Expect=1e-31]} {Dmel: FBgn0063670, CG40228, [RH, Score=139, Expect=7e-45]} {Celegans: WBGene00013219, Y54G11A.11, Transcription elongation factor 1 homolog, [RH, Score=140, Expect=1e-45]} {Smed: dd_Smed_v6_3505_0_1, dd_Smed_v6_3505_0_1, [RH, Score=122, Expect=2e-38]} {RNA1509_10357, RNA1509_28357, RNA1509_29871, RNA1509_9049} {RNA1310_49008, RNA1509_10357, RNA1509_28357, RNA1509_29871, RNA1509_9049} {RNA1509_10357, RNA1509_28357, RNA1509_29871, RNA1509_9049, RNA815_24658}
5. MligTC455_31827 5047 105.14 Mlig455_047227, Mlig455_047295

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.850/0.00112
Region-enriched R4: 1.750/0.00523
Region-enriched R5: 1.376/0.01271

0.96 - - - - 0.960 -

Mlig455_047227 {REF} {Length: 2245} {Pfam: VDE lipocalin domain [PF07137.13, score=62.5]} {RNA1509_13014, RNA1509_14776} {RNA1310_14334.1, RNA1509_14776} {RNA1509_14776, RNA815_7820}

Mlig455_047295 {REF} {Length: 2123} {Pfam: VDE lipocalin domain [PF07137.13, score=57.7]} {RNA1509_13014} {RNA1310_14334.1, RNA1509_13014} {RNA1509_13014, RNA815_7820}
6. MligTC455_45464 977 20.36 Mlig455_031625, Mlig455_048204

Neo: -

Age: logFC(26M/2M)=-0.328

Region-enriched R4: 3.768/0.00000
Region-enriched R5: 2.629/0.00008
Region-enriched R3: 2.062/0.02213

0.957 - - - - 0.957 -

Mlig455_031625 {REF} {Length: 1443} {Pfam: PDZ domain [PF17820.3, score=36.8]; PDZ domain [PF00595.26, score=33.3]; PDZ domain [PF13180.8, score=31.7]} {RNA1509_31272, RNA1509_39340} {RNA1310_26900, RNA1509_31272, RNA1509_39340} {RNA1509_31272, RNA1509_39340, RNA815_10356}

Mlig455_048204 {REF} {Length: 1436} {Pfam: PDZ domain [PF17820.3, score=36.8]; PDZ domain [PF00595.26, score=33.3]; PDZ domain [PF13180.8, score=31.7]} {RNA1509_31272} {RNA1310_26900} {RNA815_10356}
7. MligTC455_24091 3616 75.33 Mlig455_024205

Neo: -

Age: -

Region-enriched R3: 1.943/0.00049

0.956 - - - - 0.956 - Mlig455_024205 {REF} {Length: 3598} {Pfam: PAN domain [PF00024.28, score=45.6]} {RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529} {RNA1310_3811, RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529} {RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529, RNA815_1158.1}
8. MligTC455_24112 7326 152.63 Mlig455_006637, Mlig455_070643

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

CYP2D6, CYP2U1 0.955 - - - - 0.955 -

Mlig455_006637 {REF} {Length: 1777} {Pfam: Cytochrome P450 [PF00067.24, score=343.6]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=263, Expect=7e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=263, Expect=2e-81]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=260, Expect=2e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=259, Expect=4e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=2e-79]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=1e-79]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=3e-79]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=257, Expect=4e-79]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=285, Expect=3e-90]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=283, Expect=1e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=278, Expect=2e-87]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=273, Expect=2e-85]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=271, Expect=8e-85]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=271, Expect=1e-84]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=207, Expect=1e-60]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=292, Expect=3e-93]} {RNA1509_10420} {RNA1310_15091.1} {RNA815_4606.2}

Mlig455_070643 {REF} {Length: 2371} {Pfam: Cytochrome P450 [PF00067.24, score=337.1]} {Human: ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=261, Expect=1e-80]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=260, Expect=7e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=259, Expect=3e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=254, Expect=3e-78]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=280, Expect=2e-88]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=279, Expect=7e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=275, Expect=3e-86]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=268, Expect=1e-83]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=268, Expect=1e-83]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=266, Expect=7e-83]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=201, Expect=4e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=288, Expect=2e-91]} {RNA1509_10420, RNA1509_36519} {RNA1310_15091.1, RNA1509_10420, RNA1509_36519} {RNA1509_10420, RNA1509_36519, RNA815_4606.2}
9. MligTC455_50812 4042 84.22 Mlig455_022462

Neo: Int S/G2/M

Age: -

Regeneration-upregulated BL: 1.359

Regeneration-enriched BL: 1.359

KHDRBS2 0.952 - - - 0.952 - - Mlig455_022462 {REF} {Length: 5489} {Pfam: KH domain [PF00013.31, score=29.7]} {Human: ENSG00000112232, KHDRBS2, KH RNA binding domain containing, signal transduction associated 2, [Score=125, Expect=1e-32]; ENSG00000131773, KHDRBS3, KH RNA binding domain containing, signal transduction associated 3, [Score=123, Expect=7e-32]; ENSG00000121774, KHDRBS1, KH RNA binding domain containing, signal transduction associated 1, [Score=119, Expect=5e-30]} {Mouse: ENSMUSG00000026058, Khdrbs2, KH domain containing, RNA binding, signal transduction associated 2, [Score=125, Expect=5e-33]; ENSMUSG00000022332, Khdrbs3, KH domain containing, RNA binding, signal transduction associated 3, [Score=122, Expect=6e-32]; ENSMUSG00000028790, Khdrbs1, KH domain containing, RNA binding, signal transduction associated 1, [Score=120, Expect=2e-30]} {Dmel: FBgn0022987, qkr54B, quaking related 54B, [RH, Score=124, Expect=5e-32]} {Celegans: WBGene00006423, asd-2, RNA-binding protein asd-2, [Score=86.7, Expect=4e-19]} {Smed: dd_Smed_v6_294_0_1, dd_Smed_v6_294_0_1, [RH, Score=160, Expect=8e-47]} {RNA1509_1718} {RNA1310_5438, RNA1509_1718} {RNA1509_1718, RNA815_3481.1}
10. MligTC455_22665 6992 145.67 Mlig455_034131

Neo: -

Age: -

Region-enriched R3: 2.453/0.00000
Region-enriched R5: 1.399/0.00383
Region-enriched R4: 1.286/0.03665

ACE 0.95 - - - - 0.950 - Mlig455_034131 {REF} {Length: 2725} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=702.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=523, Expect=3e-171]; ENSG00000264813, AC113554.1, novel transcript, [RH, Score=518, Expect=2e-175]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=526, Expect=6e-172]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [RH, Score=456, Expect=7e-153]} {Smed: dd_Smed_v6_6160_0_1, dd_Smed_v6_6160_0_1, [Score=399, Expect=7e-131]} {RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1310_5722, RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1509_2364, RNA1509_2955, RNA1509_47766, RNA815_3600}
11. MligTC455_46058 4718 98.3 Mlig455_001357

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.305

Region-enriched R5: 1.093/0.00000

UBE2L3 0.95 - - - 0.950 - - Mlig455_001357 {REF} {Length: 1267} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=142.6]; UEV domain [PF05743.15, score=22.4]} {Human: ENSG00000185651, UBE2L3, ubiquitin conjugating enzyme E2 L3, [RH, Score=228, Expect=1e-77]; ENSG00000236444, UBE2L5, ubiquitin conjugating enzyme E2 L5, [RH, Score=228, Expect=2e-77]} {Mouse: ENSMUSG00000038965, Ube2l3, ubiquitin-conjugating enzyme E2L 3, [RH, Score=228, Expect=1e-77]} {Dmel: FBgn0026316, Ubc10, Ubiquitin conjugating enzyme 10, [RH, Score=219, Expect=2e-74]} {Celegans: WBGene00006713, ubc-18, UBiquitin Conjugating enzyme, [RH, Score=198, Expect=3e-66]} {Smed: dd_Smed_v6_667_0_1, dd_Smed_v6_667_0_1, [RH, Score=226, Expect=2e-77]} {RNA1509_1697} {RNA1310_24858} {RNA815_10525}

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