Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_26964 | 11038 | 229.96 | Mlig455_042220 | Neo: Germline Age: - |
P4HB | Mlig455_042220 {REF} {Length: 3004} {Pfam: Thioredoxin-like domain [PF13848.8, score=53.4]; ERp29, N-terminal domain [PF07912.15, score=27.6]; Thioredoxin [PF00085.22, score=25.0]} {Human: ENSG00000185624, P4HB, prolyl 4-hydroxylase subunit beta, [Score=177, Expect=1e-55]} {Mouse: ENSMUSG00000025130, P4hb, prolyl 4-hydroxylase, beta polypeptide, [Score=176, Expect=4e-53]} {Dmel: FBgn0014002, Pdi, Protein disulfide isomerase, [Score=128, Expect=3e-35]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [Score=184, Expect=6e-57]} {Smed: dd_Smed_v6_250_0_1, dd_Smed_v6_250_0_1, [Score=162, Expect=2e-48]} {RNA1509_1575} {RNA1310_2450.1} {RNA815_1453.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.288 | 7.963 | 0.39682 | 1.00000 | |
RegionR2 | -0.999 | 7.963 | 0.00008 | 0.00328 | |
RegionR3 | 0.09 | 7.963 | 0.66121 | 1.00000 | |
RegionR4 | 0.25 | 7.963 | 0.28485 | 0.59395 | |
RegionR5 | 0.374 | 7.963 | 0.05596 | 0.20301 | |
RegionR6 | 0.238 | 7.963 | 0.24374 | 0.82897 | |
RegionR7 | 0.78 | 7.963 | 0.00008 | 0.00490 | |
RegionR8 | -0.445 | 7.963 | 0.08182 | 0.54371 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.987 | 7.963 | 0.03872 | 0.65992 | |
RegenerationR2 | -0.056 | 7.963 | 0.83129 | 0.99833 | |
RegenerationR3 | -0.229 | 7.963 | 0.39061 | 0.79638 | |
RegenerationR4 | -0.248 | 7.963 | 0.36610 | 0.79090 | |
RegenerationR5 | -0.32 | 7.963 | 0.21961 | 0.65412 | |
RegenerationR6 | -0.384 | 7.963 | 0.14435 | 0.46559 | |
RegenerationBL | -0.602 | 7.963 | 0.01462 | 0.12643 | |
RegenerationTP | -0.741 | 7.963 | 0.00541 | 0.12341 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_26964 | 11038 | 229.96 | Mlig455_042220 | Neo: Germline Age: - |
P4HB | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_042220 {REF} {Length: 3004} {Pfam: Thioredoxin-like domain [PF13848.8, score=53.4]; ERp29, N-terminal domain [PF07912.15, score=27.6]; Thioredoxin [PF00085.22, score=25.0]} {Human: ENSG00000185624, P4HB, prolyl 4-hydroxylase subunit beta, [Score=177, Expect=1e-55]} {Mouse: ENSMUSG00000025130, P4hb, prolyl 4-hydroxylase, beta polypeptide, [Score=176, Expect=4e-53]} {Dmel: FBgn0014002, Pdi, Protein disulfide isomerase, [Score=128, Expect=3e-35]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [Score=184, Expect=6e-57]} {Smed: dd_Smed_v6_250_0_1, dd_Smed_v6_250_0_1, [Score=162, Expect=2e-48]} {RNA1509_1575} {RNA1310_2450.1} {RNA815_1453.1} |
2. | MligTC455_26965 | 32675 | 680.72 | Mlig455_018994, Mlig455_055709 | Neo: Germline Age: logFC(26M/2M)=0.206 |
P4HB | 5.283 | 0.810 | 0.904 | 0.840 | 0.954 | 0.905 | 0.870 | Mlig455_018994 {REF} {Length: 3271} {Pfam: Thioredoxin [PF00085.22, score=208.2]; Thioredoxin-like domain [PF13848.8, score=151.5]; Thioredoxin-like domain [PF13098.8, score=58.6]; Calsequestrin [PF01216.19, score=52.1]; OST3 / OST6 family, transporter family [PF04756.15, score=45.9]; Thioredoxin-like [PF13905.8, score=43.3]; ERp29, N-terminal domain [PF07912.15, score=42.6]; Thioredoxin-like [PF13899.8, score=42.6]; AhpC/TSA family [PF00578.23, score=35.2]; Redoxin [PF08534.12, score=31.1]; F plasmid transfer operon protein [PF13728.8, score=23.3]} {Human: ENSG00000185624, P4HB, prolyl 4-hydroxylase subunit beta, [RH, Score=572, Expect=0.0]} {Mouse: ENSMUSG00000025130, P4hb, prolyl 4-hydroxylase, beta polypeptide, [RH, Score=563, Expect=0.0]} {Dmel: FBgn0014002, Pdi, Protein disulfide isomerase, [RH, Score=510, Expect=3e-178]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [RH, Score=565, Expect=0.0]} {Smed: dd_Smed_v6_250_0_1, dd_Smed_v6_250_0_1, [RH, Score=578, Expect=0.0]} {RNA1509_1575} {RNA1310_2450.1} {RNA815_1453.1} Mlig455_055709 {REF} {Length: 3265} {Pfam: Thioredoxin [PF00085.22, score=208.2]; Thioredoxin-like domain [PF13848.8, score=151.5]; Thioredoxin-like domain [PF13098.8, score=58.6]; Calsequestrin [PF01216.19, score=52.1]; OST3 / OST6 family, transporter family [PF04756.15, score=45.9]; Thioredoxin-like [PF13905.8, score=43.3]; ERp29, N-terminal domain [PF07912.15, score=42.6]; Thioredoxin-like [PF13899.8, score=42.6]; AhpC/TSA family [PF00578.23, score=35.2]; Redoxin [PF08534.12, score=31.1]; F plasmid transfer operon protein [PF13728.8, score=23.3]} {Human: ENSG00000185624, P4HB, prolyl 4-hydroxylase subunit beta, [RH, Score=572, Expect=0.0]} {Mouse: ENSMUSG00000025130, P4hb, prolyl 4-hydroxylase, beta polypeptide, [RH, Score=563, Expect=0.0]} {Dmel: FBgn0014002, Pdi, Protein disulfide isomerase, [RH, Score=510, Expect=3e-178]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [RH, Score=565, Expect=0.0]} {Smed: dd_Smed_v6_250_0_1, dd_Smed_v6_250_0_1, [RH, Score=578, Expect=0.0]} {RNA1509_1575, RNA1509_70} {RNA1310_2450.1, RNA1509_1575, RNA1509_70} {RNA1509_1575, RNA1509_70, RNA815_1453.1} |
3. | MligTC455_31826 | 3263 | 67.98 | Mlig455_047238 | Neo: - Age: logFC(26M/2M)=0.279 Region-enriched R3: 1.778/0.00195 |
CTDSP1 | 0.968 | - | - | - | - | 0.968 | - | Mlig455_047238 {REF} {Length: 3089} {Pfam: NLI interacting factor-like phosphatase [PF03031.20, score=72.1]; VDE lipocalin domain [PF07137.13, score=58.0]} {Human: ENSG00000144579, CTDSP1, CTD small phosphatase 1, [Score=128, Expect=9e-33]} {Mouse: ENSMUSG00000026176, Ctdsp1, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1, [Score=127, Expect=7e-33]} {Dmel: FBgn0036556, CG5830, [Score=120, Expect=1e-29]} {Celegans: WBGene00007054, scpl-1, CTD small phosphatase-like protein 1, [Score=110, Expect=7e-27]} {Smed: dd_Smed_v6_8196_0_1, dd_Smed_v6_8196_0_1, [Score=135, Expect=3e-33]} {RNA1509_13014} {RNA1310_14334.1} {RNA815_7820} |
4. | MligTC455_23247 | 4480 | 93.33 | Mlig455_008739, Mlig455_008755 | Neo: Neoblast Age: Down-Up-Up Region-enriched R4: 1.709/0.00000 Regeneration-upregulated BL: 1.449 Regeneration-enriched BL: 1.449 |
ELOF1 | 0.961 | - | - | - | 0.961 | - | - | Mlig455_008739 {REF} {Length: 720} {TRANSSPLICED} {Pfam: Transcription elongation factor Elf1 like [PF05129.15, score=104.1]} {Human: ENSG00000130165, ELOF1, elongation factor 1 homolog, [RH, Score=107, Expect=1e-31]} {Mouse: ENSMUSG00000013822, Elof1, ELF1 homolog, elongation factor 1, [RH, Score=106, Expect=1e-31]} {Dmel: FBgn0063670, CG40228, [RH, Score=139, Expect=7e-45]} {Celegans: WBGene00013219, Y54G11A.11, Transcription elongation factor 1 homolog, [RH, Score=140, Expect=1e-45]} {Smed: dd_Smed_v6_3505_0_1, dd_Smed_v6_3505_0_1, [RH, Score=122, Expect=2e-38]} {RNA1509_9049} {RNA1310_49008} {RNA815_24658} Mlig455_008755 {REF} {Length: 720} {TRANSSPLICED} {Pfam: Transcription elongation factor Elf1 like [PF05129.15, score=104.1]} {Human: ENSG00000130165, ELOF1, elongation factor 1 homolog, [RH, Score=107, Expect=1e-31]} {Mouse: ENSMUSG00000013822, Elof1, ELF1 homolog, elongation factor 1, [RH, Score=106, Expect=1e-31]} {Dmel: FBgn0063670, CG40228, [RH, Score=139, Expect=7e-45]} {Celegans: WBGene00013219, Y54G11A.11, Transcription elongation factor 1 homolog, [RH, Score=140, Expect=1e-45]} {Smed: dd_Smed_v6_3505_0_1, dd_Smed_v6_3505_0_1, [RH, Score=122, Expect=2e-38]} {RNA1509_10357, RNA1509_28357, RNA1509_29871, RNA1509_9049} {RNA1310_49008, RNA1509_10357, RNA1509_28357, RNA1509_29871, RNA1509_9049} {RNA1509_10357, RNA1509_28357, RNA1509_29871, RNA1509_9049, RNA815_24658} |
5. | MligTC455_31827 | 5047 | 105.14 | Mlig455_047227, Mlig455_047295 | Neo: - Age: Up-Down-Up Region-enriched R3: 1.850/0.00112 |
0.96 | - | - | - | - | 0.960 | - | Mlig455_047227 {REF} {Length: 2245} {Pfam: VDE lipocalin domain [PF07137.13, score=62.5]} {RNA1509_13014, RNA1509_14776} {RNA1310_14334.1, RNA1509_14776} {RNA1509_14776, RNA815_7820} Mlig455_047295 {REF} {Length: 2123} {Pfam: VDE lipocalin domain [PF07137.13, score=57.7]} {RNA1509_13014} {RNA1310_14334.1, RNA1509_13014} {RNA1509_13014, RNA815_7820} |
|
6. | MligTC455_45464 | 977 | 20.36 | Mlig455_031625, Mlig455_048204 | Neo: - Age: logFC(26M/2M)=-0.328 Region-enriched R4: 3.768/0.00000 |
0.957 | - | - | - | - | 0.957 | - | Mlig455_031625 {REF} {Length: 1443} {Pfam: PDZ domain [PF17820.3, score=36.8]; PDZ domain [PF00595.26, score=33.3]; PDZ domain [PF13180.8, score=31.7]} {RNA1509_31272, RNA1509_39340} {RNA1310_26900, RNA1509_31272, RNA1509_39340} {RNA1509_31272, RNA1509_39340, RNA815_10356} Mlig455_048204 {REF} {Length: 1436} {Pfam: PDZ domain [PF17820.3, score=36.8]; PDZ domain [PF00595.26, score=33.3]; PDZ domain [PF13180.8, score=31.7]} {RNA1509_31272} {RNA1310_26900} {RNA815_10356} |
|
7. | MligTC455_24091 | 3616 | 75.33 | Mlig455_024205 | Neo: - Age: - Region-enriched R3: 1.943/0.00049 |
0.956 | - | - | - | - | 0.956 | - | Mlig455_024205 {REF} {Length: 3598} {Pfam: PAN domain [PF00024.28, score=45.6]} {RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529} {RNA1310_3811, RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529} {RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529, RNA815_1158.1} | |
8. | MligTC455_24112 | 7326 | 152.63 | Mlig455_006637, Mlig455_070643 | Neo: - |
CYP2D6, CYP2U1 | 0.955 | - | - | - | - | 0.955 | - | Mlig455_006637 {REF} {Length: 1777} {Pfam: Cytochrome P450 [PF00067.24, score=343.6]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=263, Expect=7e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=263, Expect=2e-81]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=260, Expect=2e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=259, Expect=4e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=2e-79]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=1e-79]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=3e-79]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=257, Expect=4e-79]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=285, Expect=3e-90]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=283, Expect=1e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=278, Expect=2e-87]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=273, Expect=2e-85]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=271, Expect=8e-85]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=271, Expect=1e-84]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=207, Expect=1e-60]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=292, Expect=3e-93]} {RNA1509_10420} {RNA1310_15091.1} {RNA815_4606.2} Mlig455_070643 {REF} {Length: 2371} {Pfam: Cytochrome P450 [PF00067.24, score=337.1]} {Human: ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=261, Expect=1e-80]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=260, Expect=7e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=259, Expect=3e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=254, Expect=3e-78]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=280, Expect=2e-88]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=279, Expect=7e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=275, Expect=3e-86]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=268, Expect=1e-83]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=268, Expect=1e-83]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=266, Expect=7e-83]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=201, Expect=4e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=288, Expect=2e-91]} {RNA1509_10420, RNA1509_36519} {RNA1310_15091.1, RNA1509_10420, RNA1509_36519} {RNA1509_10420, RNA1509_36519, RNA815_4606.2} |
9. | MligTC455_50812 | 4042 | 84.22 | Mlig455_022462 | Neo: Int S/G2/M Age: - Regeneration-upregulated BL: 1.359 Regeneration-enriched BL: 1.359 |
KHDRBS2 | 0.952 | - | - | - | 0.952 | - | - | Mlig455_022462 {REF} {Length: 5489} {Pfam: KH domain [PF00013.31, score=29.7]} {Human: ENSG00000112232, KHDRBS2, KH RNA binding domain containing, signal transduction associated 2, [Score=125, Expect=1e-32]; ENSG00000131773, KHDRBS3, KH RNA binding domain containing, signal transduction associated 3, [Score=123, Expect=7e-32]; ENSG00000121774, KHDRBS1, KH RNA binding domain containing, signal transduction associated 1, [Score=119, Expect=5e-30]} {Mouse: ENSMUSG00000026058, Khdrbs2, KH domain containing, RNA binding, signal transduction associated 2, [Score=125, Expect=5e-33]; ENSMUSG00000022332, Khdrbs3, KH domain containing, RNA binding, signal transduction associated 3, [Score=122, Expect=6e-32]; ENSMUSG00000028790, Khdrbs1, KH domain containing, RNA binding, signal transduction associated 1, [Score=120, Expect=2e-30]} {Dmel: FBgn0022987, qkr54B, quaking related 54B, [RH, Score=124, Expect=5e-32]} {Celegans: WBGene00006423, asd-2, RNA-binding protein asd-2, [Score=86.7, Expect=4e-19]} {Smed: dd_Smed_v6_294_0_1, dd_Smed_v6_294_0_1, [RH, Score=160, Expect=8e-47]} {RNA1509_1718} {RNA1310_5438, RNA1509_1718} {RNA1509_1718, RNA815_3481.1} |
10. | MligTC455_22665 | 6992 | 145.67 | Mlig455_034131 | Neo: - Age: - Region-enriched R3: 2.453/0.00000 |
ACE | 0.95 | - | - | - | - | 0.950 | - | Mlig455_034131 {REF} {Length: 2725} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=702.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=523, Expect=3e-171]; ENSG00000264813, AC113554.1, novel transcript, [RH, Score=518, Expect=2e-175]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=526, Expect=6e-172]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [RH, Score=456, Expect=7e-153]} {Smed: dd_Smed_v6_6160_0_1, dd_Smed_v6_6160_0_1, [Score=399, Expect=7e-131]} {RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1310_5722, RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1509_2364, RNA1509_2955, RNA1509_47766, RNA815_3600} |
11. | MligTC455_46058 | 4718 | 98.3 | Mlig455_001357 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.305 Region-enriched R5: 1.093/0.00000 |
UBE2L3 | 0.95 | - | - | - | 0.950 | - | - | Mlig455_001357 {REF} {Length: 1267} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=142.6]; UEV domain [PF05743.15, score=22.4]} {Human: ENSG00000185651, UBE2L3, ubiquitin conjugating enzyme E2 L3, [RH, Score=228, Expect=1e-77]; ENSG00000236444, UBE2L5, ubiquitin conjugating enzyme E2 L5, [RH, Score=228, Expect=2e-77]} {Mouse: ENSMUSG00000038965, Ube2l3, ubiquitin-conjugating enzyme E2L 3, [RH, Score=228, Expect=1e-77]} {Dmel: FBgn0026316, Ubc10, Ubiquitin conjugating enzyme 10, [RH, Score=219, Expect=2e-74]} {Celegans: WBGene00006713, ubc-18, UBiquitin Conjugating enzyme, [RH, Score=198, Expect=3e-66]} {Smed: dd_Smed_v6_667_0_1, dd_Smed_v6_667_0_1, [RH, Score=226, Expect=2e-77]} {RNA1509_1697} {RNA1310_24858} {RNA815_10525} |