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Results for MligTC455_22665

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_22665 6992 145.67 Mlig455_034131

Neo: -

Age: -

Region-enriched R3: 2.453/0.00000
Region-enriched R5: 1.399/0.00383
Region-enriched R4: 1.286/0.03665

 ACE Mlig455_034131 {REF} {Length: 2725} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=702.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=523, Expect=3e-171]; ENSG00000264813, AC113554.1, novel transcript, [RH, Score=518, Expect=2e-175]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=526, Expect=6e-172]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [RH, Score=456, Expect=7e-153]} {Smed: dd_Smed_v6_6160_0_1, dd_Smed_v6_6160_0_1, [Score=399, Expect=7e-131]} {RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1310_5722, RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1509_2364, RNA1509_2955, RNA1509_47766, RNA815_3600}

Cumulative graph for MligTC455_22665

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.907 7.323 0.19579 0.83087
RegionR2 -1.267 7.323 0.01904 0.14843
RegionR3 2.453 7.323 0.00000 0.00000
RegionR4 1.286 7.323 0.00507 0.03665
RegionR5 1.399 7.323 0.00029 0.00383
RegionR6 1.227 7.323 0.00286 0.07650
RegionR7 -2.024 7.323 0.00027 0.01264
RegionR8 -2.167 7.323 0.00114 0.05161

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.353 7.323 0.09910 0.81498
RegenerationR2 0.079 7.323 0.88711 1.00000
RegenerationR3 -0.233 7.323 0.65562 0.93134
RegenerationR4 0.426 7.323 0.43813 0.83574
RegenerationR5 0.166 7.323 0.75364 0.97283
RegenerationR6 0.118 7.323 0.82662 0.98946
RegenerationBL 0.278 7.323 0.59454 0.94342
RegenerationTP 0.398 7.323 0.51121 0.90813


Genes with expression patterns similar to MligTC455_22665

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_22665 6992 145.67 Mlig455_034131

Neo: -

Age: -

Region-enriched R3: 2.453/0.00000
Region-enriched R5: 1.399/0.00383
Region-enriched R4: 1.286/0.03665

 ACE 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_034131 {REF} {Length: 2725} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=702.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=523, Expect=3e-171]; ENSG00000264813, AC113554.1, novel transcript, [RH, Score=518, Expect=2e-175]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=526, Expect=6e-172]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [RH, Score=456, Expect=7e-153]} {Smed: dd_Smed_v6_6160_0_1, dd_Smed_v6_6160_0_1, [Score=399, Expect=7e-131]} {RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1310_5722, RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1509_2364, RNA1509_2955, RNA1509_47766, RNA815_3600}
2. MligTC455_24086 11442 238.37 Mlig455_068330

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.329/0.00000
Region-enriched R6: 1.493/0.00384
Region-enriched R5: 1.266/0.00365

 ACHE 5.697 0.957 0.934 0.940 0.985 0.926 0.955 Mlig455_068330 {REF} {Length: 2275} {Pfam: Carboxylesterase family [PF00135.30, score=340.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=228, Expect=5e-66]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=226, Expect=1e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=191, Expect=1e-52]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=226, Expect=1e-65]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=202, Expect=4e-57]} {RNA1509_2293, RNA1509_46106} {RNA1310_10437.1, RNA1509_2293} {RNA1509_2293, RNA815_3976}
3. MligTC455_45590 6933 144.44 Mlig455_060243

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.918/0.00019

 MRC1 5.582 0.951 0.898 0.910 0.891 0.968 0.964 Mlig455_060243 {REF} {Length: 4769} {Pfam: Lectin C-type domain [PF00059.23, score=548.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=62.0]; Extracellular link domain [PF00193.19, score=22.4]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=513, Expect=2e-156]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=8e-09]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=1e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=209, Expect=1e-54]} {RNA1509_169} {RNA1310_579} {RNA815_112.1}
4. MligTC455_21475 15839 329.98 Mlig455_064237

Neo: -

Age: logFC(26M/2M)=0.290

Region-enriched R3: 2.133/0.00005

 CTSV 5.533 0.932 0.835 0.891 0.946 0.954 0.975 Mlig455_064237 {REF} {Length: 2670} {Pfam: Papain family cysteine protease [PF00112.25, score=291.7]; Cathepsin propeptide inhibitor domain (I29) [PF08246.14, score=54.9]; Peptidase C1-like family [PF03051.17, score=27.5]} {Human: ENSG00000136943, CTSV, cathepsin V, [RH, Score=358, Expect=3e-123]; ENSG00000135047, CTSL, cathepsin L, [RH, Score=356, Expect=2e-122]} {Mouse: ENSMUSG00000021477, Ctsl, cathepsin L, [RH, Score=348, Expect=9e-120]; ENSMUSG00000042243, BC051665, cDNA sequence BC051665, [RH, Score=335, Expect=1e-114]; ENSMUSG00000056728, Ctsll3, cathepsin L-like 3, [RH, Score=333, Expect=2e-113]} {Dmel: FBgn0013770, Cp1, Cysteine proteinase-1, [Score=359, Expect=6e-124]} {Celegans: WBGene00000776, cpl-1, CathePsin L family, [RH, Score=336, Expect=6e-115]} {Smed: dd_Smed_v6_48_0_1, dd_Smed_v6_48_0_1, [RH, Score=428, Expect=2e-151]} {RNA1509_124, RNA1509_29064, RNA1509_51476, RNA1509_81} {RNA1310_16613, RNA1509_29064, RNA1509_51476, RNA1509_81} {RNA1509_29064, RNA1509_51476, RNA1509_81, RNA815_7527}
5. MligTC455_21830 5295 110.31 Mlig455_014095

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.481

Region-enriched R3: 1.429/0.00231
Region-enriched R4: 1.366/0.01008
Region-enriched R5: 1.005/0.03133

 YDJC 5.479 0.828 0.896 0.919 0.932 0.938 0.966 Mlig455_014095 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: YdjC-like protein [PF04794.14, score=165.2]} {Human: ENSG00000161179, YDJC, YdjC chitooligosaccharide deacetylase homolog, [RH, Score=164, Expect=2e-47]} {Mouse: ENSMUSG00000041774, Ydjc, YdjC homolog (bacterial), [RH, Score=172, Expect=7e-51]} {Smed: dd_Smed_v6_65631_0_1, dd_Smed_v6_65631_0_1, [RH, Score=68.9, Expect=2e-14]} {RNA1509_18855, RNA1509_29693, RNA1509_42768} {RNA1310_36996, RNA1509_18855, RNA1509_29693, RNA1509_42768} {RNA1509_18855, RNA1509_29693, RNA1509_42768, RNA815_4988.1}
6. MligTC455_42352 5331 111.06 Mlig455_014325

Neo: -

Age: -

Region-enriched R3: 1.607/0.00131
Region-enriched R5: 1.102/0.02723

 ACE 5.405 0.922 0.833 0.912 0.944 0.838 0.956 Mlig455_014325 {REF} {Length: 2705} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441, RNA1509_9027} {RNA1310_8949, RNA1509_441, RNA1509_9027} {RNA1509_441, RNA1509_9027, RNA815_4061}
7. MligTC455_39170 3221 67.1 Mlig455_038903

Neo: -

Age: logFC(26M/2M)=0.340

Region-enriched R3: 2.495/0.00000
Region-enriched R4: 1.609/0.00501
Region-enriched R5: 1.221/0.00810

 ALDH2 5.39 0.882 0.937 0.880 0.950 0.928 0.813 Mlig455_038903 {REF} {Length: 2307} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=593.4]} {Human: ENSG00000111275, ALDH2, aldehyde dehydrogenase 2 family member, [RH, Score=780, Expect=0.0]; ENSG00000137124, ALDH1B1, aldehyde dehydrogenase 1 family member B1, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000029455, Aldh2, aldehyde dehydrogenase 2, mitochondrial, [RH, Score=768, Expect=0.0]; ENSMUSG00000035561, Aldh1b1, aldehyde dehydrogenase 1 family, member B1, [RH, Score=749, Expect=0.0]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00000107, alh-1, ALdehyde deHydrogenase, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_1339_0_1, dd_Smed_v6_1339_0_1, [RH, Score=725, Expect=0.0]} {RNA1509_1186} {RNA1310_3799.1} {RNA815_1286.1}
8. MligTC455_45589 8445 175.93 Mlig455_060231

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.105/0.00005

 MRC1 5.389 0.964 0.709 0.870 0.975 0.928 0.943 Mlig455_060231 {REF} {Length: 6599} {Pfam: Lectin C-type domain [PF00059.23, score=668.9]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=86.8]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=514, Expect=1e-153]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=487, Expect=3e-144]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=1e-08]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=2e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=207, Expect=7e-54]} {RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870} {RNA1310_579, RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870} {RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870, RNA815_112.1}
9. MligTC455_38724 5697 118.69 Mlig455_045051

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R3: 1.948/0.00202

 PANK4 5.367 0.912 0.817 0.818 0.962 0.890 0.968 Mlig455_045051 {REF} {Length: 2009} {Pfam: Fumble [PF03630.16, score=127.5]} {Human: ENSG00000157881, PANK4, pantothenate kinase 4, [Score=112, Expect=2e-26]; ENSG00000273494, PANK4, pantothenate kinase 4, [Score=112, Expect=2e-26]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=102, Expect=2e-23]} {Dmel: FBgn0011205, fbl, fumble, [Score=86.7, Expect=1e-18]} {Celegans: WBGene00004068, pnk-1, PaNtothenate Kinase, [Score=82.4, Expect=3e-17]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [RH, Score=225, Expect=1e-70]} {RNA1509_11373, RNA1509_768} {RNA1310_14353, RNA1509_11373} {RNA1509_11373, RNA815_1414}
10. MligTC455_49488 5075 105.73 Mlig455_055474

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.341

Region-enriched R3: 1.609/0.02116

 5.315 0.806 0.854 0.895 0.959 0.874 0.927 Mlig455_055474 {REF} {Length: 988} {Pfam: Universal stress protein family [PF00582.28, score=100.4]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=126, Expect=2e-37]} {RNA1509_12747, RNA1509_15238} {RNA1310_22621, RNA1509_15238} {RNA1509_15238, RNA815_17247}
11. MligTC455_53878 8131 169.39 Mlig455_056351

Neo: -

Age: logFC(26M/2M)=0.398

Region-enriched R3: 1.950/0.00000
Region-enriched R5: 1.089/0.01986

 CLCA1 5.312 0.852 0.916 0.768 0.965 0.940 0.871 Mlig455_056351 {REF} {Length: 4429} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=166.8]; von Willebrand factor type A domain [PF00092.30, score=30.4]; von Willebrand factor type A domain [PF13519.8, score=27.0]; von Willebrand factor type A domain [PF13768.8, score=23.5]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=2e-41]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=165, Expect=5e-41]} {Celegans: WBGene00018026, F35A5.4, [Score=58.2, Expect=3e-08]} {RNA1509_656} {RNA1310_5461.1} {RNA815_1665}
12. MligTC455_49487 5068 105.57 Mlig455_036283

Neo: -

Age: logFC(26M/2M)=-0.424

Region-enriched R3: 1.606/0.02613

 5.307 0.806 0.854 0.895 0.958 0.865 0.929 Mlig455_036283 {REF} {Length: 978} {Pfam: Universal stress protein family [PF00582.28, score=89.7]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=109, Expect=3e-31]} {RNA1509_12747} {RNA1310_22621} {RNA815_17247}
13. MligTC455_39169 881 18.35 Mlig455_063890

Neo: -

Age: -

Region-enriched R3: 3.017/0.00000

 ALDH2 5.262 0.973 0.900 0.833 0.889 0.785 0.882 Mlig455_063890 {REF} {Length: 2688} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=591.3]} {Human: ENSG00000111275, ALDH2, aldehyde dehydrogenase 2 family member, [RH, Score=777, Expect=0.0]; ENSG00000137124, ALDH1B1, aldehyde dehydrogenase 1 family member B1, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000029455, Aldh2, aldehyde dehydrogenase 2, mitochondrial, [RH, Score=768, Expect=0.0]; ENSMUSG00000035561, Aldh1b1, aldehyde dehydrogenase 1 family, member B1, [RH, Score=749, Expect=0.0]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00000107, alh-1, ALdehyde deHydrogenase, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_1339_0_1, dd_Smed_v6_1339_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_1186, RNA1509_20297} {RNA1310_3799.1, RNA1509_20297} {RNA1509_20297, RNA815_1286.1}
14. MligTC455_46189 3465 72.19 Mlig455_064483

Neo: -

Age: -

Region-enriched R3: 2.108/0.00000
Region-enriched R4: 1.352/0.02878
Region-enriched R5: 1.186/0.01606

 ENPEP 5.262 0.886 0.936 0.719 0.977 0.890 0.854 Mlig455_064483 {REF} {Length: 3574} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=253.3]; Peptidase family M1 domain [PF01433.22, score=243.6]; Peptidase M1 N-terminal domain [PF17900.3, score=149.2]} {Human: ENSG00000138792, ENPEP, glutamyl aminopeptidase, [RH, Score=590, Expect=0.0]} {Mouse: ENSMUSG00000028024, Enpep, glutamyl aminopeptidase, [RH, Score=590, Expect=0.0]} {Dmel: FBgn0038135, CG8773, [RH, Score=610, Expect=0.0]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [Score=369, Expect=3e-112]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [Score=479, Expect=2e-153]} {RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985} {RNA1310_3977.1, RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985} {RNA1509_40879, RNA1509_41090, RNA1509_50042, RNA1509_56083, RNA1509_690, RNA1509_9985, RNA815_1584}
15. MligTC455_41984 5794 120.71 Mlig455_070257

Neo: -

Age: logFC(26M/2M)=0.384

Region-enriched R3: 1.830/0.00014
Region-enriched R4: 1.696/0.00265
Region-enriched R6: 1.511/0.01084
Region-enriched R5: 1.493/0.00157

 BHMT 5.256 0.910 0.784 0.810 0.897 0.891 0.964 Mlig455_070257 {REF} {Length: 2300} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=161.5]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=543, Expect=0.0]} {Mouse: ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=548, Expect=0.0]; ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=548, Expect=0.0]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=555, Expect=0.0]} {RNA1509_10637, RNA1509_54311, RNA1509_9980} {RNA1310_18981.1, RNA1509_54311, RNA1509_9980} {RNA1509_54311, RNA1509_9980, RNA815_5900.2}
16. MligTC455_22268 6636 138.25 Mlig455_011760

Neo: -

Age: logFC(26M/2M)=-0.323

Region-enriched R3: 1.908/0.00000
Region-enriched R6: 1.283/0.01830
Region-enriched R5: 1.133/0.00963

 5.254 0.918 0.733 0.816 0.956 0.946 0.885 Mlig455_011760 {REF} {Length: 2561} {RNA1509_1433} {RNA1310_8428, RNA1509_1433} {RNA1509_1433, RNA815_2971}
17. MligTC455_43334 7286 151.78 Mlig455_054088

Neo: -

Age: logFC(26M/2M)=0.327

Region-enriched R3: 1.908/0.00014

 CTSB 5.234 0.888 0.798 0.830 0.927 0.813 0.978 Mlig455_054088 {REF} {Length: 2579} {Pfam: Papain family cysteine protease [PF00112.25, score=227.1]; Peptidase family C1 propeptide [PF08127.15, score=44.5]} {Human: ENSG00000164733, CTSB, cathepsin B, [RH, Score=387, Expect=1e-134]} {Mouse: ENSMUSG00000021939, Ctsb, cathepsin B, [RH, Score=387, Expect=1e-134]} {Dmel: FBgn0030521, CtsB1, Cathepsin B1, [RH, Score=369, Expect=2e-127]} {Celegans: WBGene00010204, F57F5.1, [RH, Score=338, Expect=1e-115]} {Smed: dd_Smed_v6_81_0_1, dd_Smed_v6_81_0_1, [RH, Score=424, Expect=2e-149]} {RNA1509_448} {RNA1310_24539, RNA1509_448} {RNA1509_448, RNA815_4531}
18. MligTC455_18724 1612 33.59 Mlig455_037198

Neo: -

Age: -

Region-enriched R3: 2.022/0.00141

 SLC3A1 5.222 0.963 0.842 0.839 0.865 0.872 0.841 Mlig455_037198 {REF} {Length: 2052} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=311.9]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=373, Expect=2e-120]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=374, Expect=5e-121]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=385, Expect=1e-126]} {Celegans: WBGene00000225, atgp-2, Amino acid Transporter GlycoProtein subunit, [RH, Score=147, Expect=2e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=9e-12]} {RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1310_12682.1, RNA1509_14094, RNA1509_15182, RNA1509_19345} {RNA1509_14094, RNA1509_15182, RNA1509_19345, RNA815_15968}
19. MligTC455_35633 4966 103.45 Mlig455_048471

Neo: -

Age: -

Region-enriched R4: 1.579/0.00682
Region-enriched R3: 1.493/0.00762

 DHDH 5.222 0.855 0.769 0.898 0.958 0.874 0.868 Mlig455_048471 {REF} {Length: 1491} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=87.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]; Homoserine dehydrogenase, NAD binding domain [PF03447.18, score=19.9]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=246, Expect=3e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=248, Expect=4e-80]} {Dmel: FBgn0031418, CG3609, [RH, Score=231, Expect=1e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=213, Expect=9e-67]} {RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1310_24236, RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1509_1049, RNA1509_4889, RNA1509_8979, RNA815_11111.1}
20. MligTC455_18723 1597 33.27 Mlig455_004384

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.781

Region-enriched R3: 2.164/0.00079
Region-enriched R4: 1.576/0.04930
Region-enriched R5: 1.329/0.03977

 SLC3A1 5.217 0.963 0.842 0.839 0.867 0.866 0.840 Mlig455_004384 {REF} {Length: 2040} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=310.6]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=371, Expect=2e-119]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=372, Expect=4e-120]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=384, Expect=2e-126]} {Celegans: WBGene00000224, atgp-1, Amino acid Transporter GlycoProtein subunit, [RH, Score=146, Expect=3e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=8e-12]} {RNA1509_19345} {RNA1310_12682.1} {RNA815_15968}
21. MligTC455_40312 3856 80.34 Mlig455_008661, Mlig455_008672

Neo: -

Age: Down-Up-Up

Region-enriched R3: 2.080/0.00320

 CYP2J2 5.2 0.856 0.899 0.742 0.990 0.894 0.819

Mlig455_008661 {REF} {Length: 2369} {Pfam: Cytochrome P450 [PF00067.24, score=340.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=298, Expect=3e-95]} {Mouse: ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=2e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=276, Expect=1e-86]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=3e-86]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=274, Expect=6e-86]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=4e-85]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=2e-84]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=270, Expect=2e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=269, Expect=6e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=2e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=5e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=219, Expect=9e-65]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=262, Expect=1e-81]} {RNA1509_32472, RNA1509_3430} {RNA1310_10280, RNA1509_32472, RNA1509_3430} {RNA1509_32472, RNA1509_3430, RNA815_4805}

Mlig455_008672 {REF} {Length: 2348} {Pfam: Cytochrome P450 [PF00067.24, score=341.0]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=298, Expect=3e-95]} {Mouse: ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=2e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=276, Expect=1e-86]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=2e-86]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=274, Expect=5e-86]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=4e-85]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=2e-84]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=269, Expect=6e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=269, Expect=7e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=3e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=6e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=219, Expect=7e-65]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=248, Expect=3e-76]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=261, Expect=3e-81]} {RNA1509_32472} {RNA1310_10280} {RNA815_4805}
22. MligTC455_24112 7326 152.63 Mlig455_006637, Mlig455_070643

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.380

 CYP2D6, CYP2U1 5.136 0.834 0.793 0.815 0.889 0.951 0.854

Mlig455_006637 {REF} {Length: 1777} {Pfam: Cytochrome P450 [PF00067.24, score=343.6]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=263, Expect=7e-81]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=263, Expect=2e-81]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=260, Expect=2e-80]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [RH, Score=259, Expect=4e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=2e-79]; ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=258, Expect=1e-79]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=3e-79]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=257, Expect=4e-79]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=257, Expect=4e-79]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=285, Expect=3e-90]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=283, Expect=1e-89]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=278, Expect=2e-87]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=273, Expect=2e-85]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=271, Expect=8e-85]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=271, Expect=1e-84]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=207, Expect=1e-60]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=292, Expect=3e-93]} {RNA1509_10420} {RNA1310_15091.1} {RNA815_4606.2}

Mlig455_070643 {REF} {Length: 2371} {Pfam: Cytochrome P450 [PF00067.24, score=337.1]} {Human: ENSG00000283284, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=261, Expect=1e-80]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [RH, Score=260, Expect=7e-80]; ENSG00000275211, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=260, Expect=2e-80]; ENSG00000282966, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000272000, AC236040.1, cytochrome P450 family 2 subfamily D member 6 pseudogene, [RH, Score=259, Expect=3e-80]; ENSG00000272532, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000280905, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000100197, CYP2D6, cytochrome P450 family 2 subfamily D member 6, [RH, Score=259, Expect=3e-80]; ENSG00000130649, CYP2E1, cytochrome P450 family 2 subfamily E member 1, [RH, Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [RH, Score=254, Expect=3e-78]} {Mouse: ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=280, Expect=2e-88]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [RH, Score=279, Expect=7e-88]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=275, Expect=3e-86]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=268, Expect=1e-83]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=268, Expect=1e-83]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=266, Expect=7e-83]} {Dmel: FBgn0001992, Cyp303a1, [RH, Score=201, Expect=4e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=246, Expect=1e-75]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [RH, Score=288, Expect=2e-91]} {RNA1509_10420, RNA1509_36519} {RNA1310_15091.1, RNA1509_10420, RNA1509_36519} {RNA1509_10420, RNA1509_36519, RNA815_4606.2}
23. MligTC455_42341 2131 44.4 Mlig455_015675, Mlig455_062486

Neo: -

Age: logFC(26M/2M)=-0.307

Region-enriched R3: 2.018/0.00002

 CYB561A3 5.127 0.972 0.848 0.851 0.884 0.769 0.803

Mlig455_015675 {REF} {Length: 1331} {Pfam: Eukaryotic cytochrome b561 [PF03188.18, score=116.0]} {Human: ENSG00000162144, CYB561A3, cytochrome b561 family member A3, [Score=123, Expect=1e-33]} {Mouse: ENSMUSG00000034445, Cyb561a3, cytochrome b561 family, member A3, [Score=126, Expect=4e-35]} {Dmel: FBgn0035321, CG1275, [Score=86.3, Expect=4e-20]} {Celegans: WBGene00018210, F39G3.5, [RH, Score=87.4, Expect=1e-20]} {Smed: dd_Smed_v6_4017_0_1, dd_Smed_v6_4017_0_1, [Score=118, Expect=2e-32]} {RNA1509_29638} {RNA1310_17515.1} {RNA815_8047}

Mlig455_062486 {REF} {Length: 1632} {Pfam: Eukaryotic cytochrome b561 [PF03188.18, score=113.3]} {Human: ENSG00000162144, CYB561A3, cytochrome b561 family member A3, [Score=122, Expect=5e-34]} {Mouse: ENSMUSG00000034445, Cyb561a3, cytochrome b561 family, member A3, [Score=124, Expect=4e-35]} {Dmel: FBgn0261673, nemy, no extended memory, [Score=83.6, Expect=8e-20]} {Celegans: WBGene00010131, F55H2.5, Putative cytochrome b561, [Score=84.3, Expect=8e-20]} {Smed: dd_Smed_v6_4017_0_1, dd_Smed_v6_4017_0_1, [Score=113, Expect=4e-31]} {RNA1509_29638, RNA1509_6916} {RNA1310_17515.1, RNA1509_29638} {RNA1509_29638, RNA815_8047}
24. MligTC455_11017 1385 28.86 Mlig455_001086, Mlig455_001095, Mlig455_005569

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.705/0.00000
Region-enriched R4: 2.027/0.00020
Region-enriched R5: 1.958/0.00005
Region-enriched R6: 1.566/0.03743

 SLC46A1 5.073 0.872 0.811 0.790 0.820 0.952 0.828

Mlig455_001086 {REF} {Length: 2386} {Pfam: Major Facilitator Superfamily [PF07690.18, score=58.4]; Sugar (and other) transporter [PF00083.26, score=20.6]} {Human: ENSG00000076351, SLC46A1, solute carrier family 46 member 1, [RH, Score=146, Expect=5e-38]} {Mouse: ENSMUSG00000029650, Slc46a3, solute carrier family 46, member 3, [RH, Score=156, Expect=8e-42]; ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [RH, Score=155, Expect=2e-41]} {Dmel: FBgn0035400, CG11537, [Score=65.1, Expect=9e-11]} {Celegans: WBGene00021159, Y4C6B.5, [RH, Score=69.3, Expect=2e-12]} {Smed: dd_Smed_v6_5528_0_1, dd_Smed_v6_5528_0_1, [RH, Score=192, Expect=3e-55]} {RNA1509_14910} {RNA1310_11843, RNA1509_14910} {RNA1509_14910, RNA815_6187.1}

Mlig455_001095 {REF} {Length: 2228} {Pfam: Major Facilitator Superfamily [PF07690.18, score=54.9]; Sugar (and other) transporter [PF00083.26, score=20.0]} {Human: ENSG00000076351, SLC46A1, solute carrier family 46 member 1, [Score=128, Expect=2e-32]} {Mouse: ENSMUSG00000029650, Slc46a3, solute carrier family 46, member 3, [Score=140, Expect=5e-37]; ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [Score=136, Expect=2e-35]} {Dmel: FBgn0035400, CG11537, [Score=58.5, Expect=5e-09]} {Celegans: WBGene00021159, Y4C6B.5, [Score=65.5, Expect=2e-11]} {Smed: dd_Smed_v6_5528_0_1, dd_Smed_v6_5528_0_1, [Score=142, Expect=9e-38]} {RNA1509_14910} {RNA1310_11843} {RNA815_6187.1}

Mlig455_005569 {REF} {Length: 2227} {Pfam: Major Facilitator Superfamily [PF07690.18, score=57.9]; Sugar (and other) transporter [PF00083.26, score=20.7]} {Human: ENSG00000076351, SLC46A1, solute carrier family 46 member 1, [RH, Score=148, Expect=9e-39]} {Mouse: ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [RH, Score=156, Expect=8e-42]; ENSMUSG00000029650, Slc46a3, solute carrier family 46, member 3, [RH, Score=152, Expect=1e-40]} {Dmel: FBgn0035400, CG11537, [Score=66.2, Expect=3e-11]} {Celegans: WBGene00021159, Y4C6B.5, [RH, Score=71.6, Expect=4e-13]} {Smed: dd_Smed_v6_5528_0_1, dd_Smed_v6_5528_0_1, [RH, Score=192, Expect=2e-55]} {RNA1509_14910, RNA1509_54422} {RNA1310_11843, RNA1509_54422} {RNA1509_54422, RNA815_6187.1}
25. MligTC455_19081 4663 97.14 Mlig455_033359

Neo: -

Age: logFC(26M/2M)=0.367

Region-enriched R3: 1.666/0.00494
Region-enriched R5: 1.231/0.02896

 5.061 0.861 0.761 0.778 0.986 0.734 0.941 Mlig455_033359 {REF} {Length: 508} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_1334} {RNA1310_80532} {RNA815_20560.2}
26. MligTC455_43333 11678 243.29 Mlig455_036055

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.186

Region-enriched R3: 1.916/0.00004
Region-enriched R6: 1.435/0.01562
Region-enriched R5: 1.079/0.03201

 CTSB 4.995 0.823 0.709 0.801 0.926 0.768 0.968 Mlig455_036055 {REF} {Length: 1907} {Pfam: Papain family cysteine protease [PF00112.25, score=227.2]; Peptidase family C1 propeptide [PF08127.15, score=44.5]} {Human: ENSG00000164733, CTSB, cathepsin B, [RH, Score=388, Expect=7e-135]} {Mouse: ENSMUSG00000021939, Ctsb, cathepsin B, [RH, Score=385, Expect=5e-134]} {Dmel: FBgn0030521, CtsB1, Cathepsin B1, [RH, Score=366, Expect=1e-126]} {Celegans: WBGene00010204, F57F5.1, [RH, Score=336, Expect=1e-114]} {Smed: dd_Smed_v6_81_0_1, dd_Smed_v6_81_0_1, [RH, Score=427, Expect=2e-150]} {RNA1509_2988, RNA1509_448} {RNA1310_24539, RNA1509_2988} {RNA1509_2988, RNA815_4531}
27. MligTC455_24084 9162 190.87 Mlig455_068331

Neo: -

Age: logFC(26M/2M)=0.316

Region-enriched R3: 1.883/0.00000

 ACHE 4.741 0.951 - 0.905 0.970 0.945 0.970 Mlig455_068331 {REF} {Length: 2518} {Pfam: Carboxylesterase family [PF00135.30, score=356.7]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=237, Expect=7e-69]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=227, Expect=2e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=196, Expect=4e-54]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=228, Expect=4e-66]} {Smed: dd_Smed_v6_4800_0_2, dd_Smed_v6_4800_0_2, [Score=183, Expect=1e-49]} {RNA1509_18646, RNA1509_195, RNA1509_28401} {RNA1310_9229, RNA1509_18646, RNA1509_195, RNA1509_28401} {RNA1509_18646, RNA1509_195, RNA1509_28401, RNA815_3141.1}
28. MligTC455_18651 2559 53.32 Mlig455_067661

Neo: -

Age: -

Region-enriched R3: 1.583/0.04334

 4.553 0.837 0.904 - 0.989 0.948 0.875 Mlig455_067661 {REF} {Length: 616} {RNA1509_2812} {RNA1310_3353.1, RNA1509_2812} {RNA1509_2812, RNA815_7653}
29. MligTC455_41983 2249 46.86 Mlig455_014572

Neo: -

Age: -

Region-enriched R4: 2.314/0.00000
Region-enriched R3: 1.500/0.00235
Region-enriched R6: 1.362/0.01872
Region-enriched R5: 1.347/0.00318

 BHMT 4.499 0.903 - 0.794 0.953 0.910 0.939 Mlig455_014572 {REF} {Length: 2550} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=161.0]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=542, Expect=0.0]} {Mouse: ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=545, Expect=0.0]; ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=545, Expect=0.0]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=555, Expect=0.0]} {RNA1509_18954, RNA1509_57529} {RNA1310_18981.1, RNA1509_18954} {RNA1509_18954, RNA815_5900.2}
30. MligTC455_30314 17741 369.6 Mlig455_014122, Mlig455_014131

Neo: -

Age: -

Region-enriched R3: 1.904/0.00059

 TUBB4B 4.496 0.922 0.791 - 0.958 0.880 0.945

Mlig455_014122 {REF} {Length: 2342} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=235.9]; Tubulin C-terminal domain [PF03953.19, score=141.7]; Misato Segment II tubulin-like domain [PF10644.11, score=24.4]} {Human: ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [RH, Score=913, Expect=0.0]} {Mouse: ENSMUSG00000036752, Tubb4b, tubulin, beta 4B class IVB, [RH, Score=913, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [RH, Score=854, Expect=0.0]} {Celegans: WBGene00006538, tbb-4, Tubulin beta-4 chain, [RH, Score=856, Expect=0.0]} {Smed: dd_Smed_v6_83_0_3, dd_Smed_v6_83_0_3, [RH, Score=910, Expect=0.0]} {RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269} {RNA1310_15130.1, RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269} {RNA1509_24313, RNA1509_3450, RNA1509_35816, RNA1509_47714, RNA1509_5200, RNA1509_7269, RNA815_1610.1}

Mlig455_014131 {REF} {Length: 2057} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=235.8]; Tubulin C-terminal domain [PF03953.19, score=143.3]; Misato Segment II tubulin-like domain [PF10644.11, score=24.4]} {Human: ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [RH, Score=913, Expect=0.0]} {Mouse: ENSMUSG00000036752, Tubb4b, tubulin, beta 4B class IVB, [RH, Score=913, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [RH, Score=854, Expect=0.0]} {Celegans: WBGene00006538, tbb-4, Tubulin beta-4 chain, [RH, Score=856, Expect=0.0]} {Smed: dd_Smed_v6_83_0_1, dd_Smed_v6_83_0_1, [RH, Score=910, Expect=0.0]} {RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735} {RNA1310_15130.1, RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735} {RNA1509_10060, RNA1509_16564, RNA1509_30077, RNA1509_51924, RNA1509_5235, RNA1509_54023, RNA1509_5590, RNA1509_7735, RNA815_1610.1}
31. MligTC455_10015 1301 27.1 Mlig455_054875

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.120/0.00000
Region-enriched R4: 1.638/0.00586

 CYP2C8 4.488 0.837 0.891 - 0.941 0.867 0.952 Mlig455_054875 {REF} {Length: 2242} {Pfam: Cytochrome P450 [PF00067.24, score=314.1]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=241, Expect=3e-73]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=236, Expect=8e-71]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=233, Expect=2e-70]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=233, Expect=2e-70]} {Mouse: ENSMUSG00000022445, Cyp2d26, cytochrome P450, family 2, subfamily d, polypeptide 26, [Score=241, Expect=2e-73]; ENSMUSG00000091867, Cyp2a22, cytochrome P450, family 2, subfamily a, polypeptide 22, [Score=235, Expect=4e-71]; ENSMUSG00000003053, Cyp2c29, cytochrome P450, family 2, subfamily c, polypeptide 29, [Score=234, Expect=1e-70]; ENSMUSG00000060407, Cyp2a12, cytochrome P450, family 2, subfamily a, polypeptide 12, [Score=233, Expect=2e-70]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=232, Expect=5e-70]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [Score=230, Expect=4e-69]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=229, Expect=9e-69]; ENSMUSG00000061740, Cyp2d22, cytochrome P450, family 2, subfamily d, polypeptide 22, [Score=229, Expect=6e-69]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=201, Expect=7e-58]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=222, Expect=1e-66]} {Smed: dd_Smed_v6_5344_0_6, dd_Smed_v6_5344_0_6, [Score=206, Expect=2e-60]} {RNA1509_10048, RNA1509_26828} {RNA1310_15951, RNA1509_10048, RNA1509_26828} {RNA1509_10048, RNA1509_26828, RNA815_5705}
32. MligTC455_31826 3263 67.98 Mlig455_047238

Neo: -

Age: logFC(26M/2M)=0.279

Region-enriched R3: 1.778/0.00195
Region-enriched R4: 1.661/0.00801
Region-enriched R5: 1.362/0.01219

 CTDSP1 4.472 0.766 - 0.925 0.948 0.955 0.878 Mlig455_047238 {REF} {Length: 3089} {Pfam: NLI interacting factor-like phosphatase [PF03031.20, score=72.1]; VDE lipocalin domain [PF07137.13, score=58.0]} {Human: ENSG00000144579, CTDSP1, CTD small phosphatase 1, [Score=128, Expect=9e-33]} {Mouse: ENSMUSG00000026176, Ctdsp1, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1, [Score=127, Expect=7e-33]} {Dmel: FBgn0036556, CG5830, [Score=120, Expect=1e-29]} {Celegans: WBGene00007054, scpl-1, CTD small phosphatase-like protein 1, [Score=110, Expect=7e-27]} {Smed: dd_Smed_v6_8196_0_1, dd_Smed_v6_8196_0_1, [Score=135, Expect=3e-33]} {RNA1509_13014} {RNA1310_14334.1} {RNA815_7820}
33. MligTC455_47633 2997 62.43 Mlig455_021264, Mlig455_021535

Neo: -

Age: -

Region-enriched R4: 1.984/0.00494
Region-enriched R3: 1.676/0.01623

 4.468 0.909 0.828 0.845 0.972 - 0.914

Mlig455_021264 {REF} {Length: 1079} {Pfam: Universal stress protein family [PF00582.28, score=103.9]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=130, Expect=1e-39]} {RNA1509_6559} {RNA1310_39993} {RNA815_18311}

Mlig455_021535 {REF} {Length: 938} {Pfam: Universal stress protein family [PF00582.28, score=103.9]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=130, Expect=1e-39]} {RNA1509_6559} {RNA1310_39993} {RNA815_18311}
34. MligTC455_49658 3392 70.66 Mlig455_011590

Neo: -

Age: -

Region-enriched R3: 1.949/0.00002

 4.454 0.910 0.848 - 0.961 0.780 0.955 Mlig455_011590 {REF} {Length: 2376} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}
35. MligTC455_33836 2065 43.02 Mlig455_036757

Neo: -

Age: logFC(26M/2M)=-0.242

Region-enriched R3: 1.925/0.00000
Region-enriched R4: 1.200/0.01490
Region-enriched R5: 1.020/0.01114

 CYP2J2 4.427 - 0.930 0.746 0.883 0.897 0.971 Mlig455_036757 {REF} {Length: 1902} {Pfam: Cytochrome P450 [PF00067.24, score=314.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=252, Expect=2e-77]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=248, Expect=4e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=248, Expect=4e-76]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [Score=246, Expect=3e-75]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=246, Expect=2e-75]; ENSMUSG00000066097, Cyp2j11, cytochrome P450, family 2, subfamily j, polypeptide 11, [Score=240, Expect=7e-73]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=239, Expect=1e-72]; ENSMUSG00000082932, Cyp2j8, cytochrome P450, family 2, subfamily j, polypeptide 8, [Score=236, Expect=2e-71]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=208, Expect=1e-60]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=226, Expect=7e-68]} {Smed: dd_Smed_v6_5344_0_2, dd_Smed_v6_5344_0_2, [RH, Score=260, Expect=8e-81]} {RNA1509_32471} {RNA1310_10330} {RNA815_3898.1}
36. MligTC455_27626 5517 114.94 Mlig455_018931

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.591/0.03259

 MATN2 4.425 0.866 0.908 - 0.971 0.860 0.820 Mlig455_018931 {REF} {Length: 2583} {Pfam: von Willebrand factor type A domain [PF00092.30, score=235.9]; von Willebrand factor type A domain [PF13519.8, score=103.0]; von Willebrand factor type A domain [PF13768.8, score=54.3]; VWA domain containing CoxE-like protein [PF05762.16, score=36.8]; Protein of unknown function (DUF1194) [PF06707.13, score=35.1]} {Human: ENSG00000132561, MATN2, matrilin 2, [Score=96.7, Expect=3e-20]} {Mouse: ENSMUSG00000040533, Matn1, matrilin 1, cartilage matrix protein, [Score=105, Expect=1e-23]} {Celegans: WBGene00003482, mua-3, Transmembrane cell adhesion receptor mua-3, [Score=82.0, Expect=8e-16]} {Smed: dd_Smed_v6_2674_0_1, dd_Smed_v6_2674_0_1, [Score=92.0, Expect=3e-19]} {RNA1509_21765, RNA1509_317, RNA1509_9118} {RNA1310_8996, RNA1509_21765, RNA1509_317, RNA1509_9118} {RNA1509_21765, RNA1509_317, RNA1509_9118, RNA815_2915.1}
37. MligTC455_51431 4302 89.63 Mlig455_045755

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.984/0.00149
Region-enriched R5: 1.417/0.02239

 4.417 0.796 - 0.833 0.976 0.893 0.919 Mlig455_045755 {REF} {Length: 312} {NoTransDecoderORF} {RNA1509_51873} {RNA1310_8784.1} {RNA815_3564}
38. MligTC455_44102 5169 107.69 Mlig455_011991

Neo: -

Age: logFC(26M/2M)=0.278

Region-enriched R3: 1.948/0.00360
Region-enriched R4: 1.688/0.02863

 HPGDS 4.38 0.834 - 0.948 0.959 0.809 0.830 Mlig455_011991 {REF} {Length: 1746} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=43.5]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=42.8]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=22.6]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=20.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=19.1]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [Score=67.8, Expect=2e-13]} {Mouse: ENSMUSG00000025934, Gsta3, glutathione S-transferase, alpha 3, [Score=62.4, Expect=1e-11]; ENSMUSG00000032348, Gsta4, glutathione S-transferase, alpha 4, [Score=60.5, Expect=6e-11]; ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [Score=60.5, Expect=5e-11]} {Celegans: WBGene00001756, gst-8, Probable glutathione S-transferase 8, [Score=84.0, Expect=5e-20]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=115, Expect=4e-32]} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1310_14959.1, RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359, RNA815_7403}
39. MligTC455_24091 3616 75.33 Mlig455_024205

Neo: -

Age: -

Region-enriched R3: 1.943/0.00049

 4.373 0.888 0.833 - 0.864 0.951 0.837 Mlig455_024205 {REF} {Length: 3598} {Pfam: PAN domain [PF00024.28, score=45.6]} {RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529} {RNA1310_3811, RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529} {RNA1509_20379, RNA1509_21800, RNA1509_2299, RNA1509_44640, RNA1509_50734, RNA1509_6382, RNA1509_7783, RNA1509_8529, RNA815_1158.1}
40. MligTC455_44700 2825 58.85 Mlig455_049079

Neo: -

Age: -

Region-enriched R3: 1.667/0.02565

 SLC10A1 4.36 0.854 0.824 - 0.891 0.952 0.839 Mlig455_049079 {REF} {Length: 2131} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=117.8]; SBF-like CPA transporter family (DUF4137) [PF13593.8, score=36.6]} {Human: ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=124, Expect=4e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=131, Expect=1e-33]} {Dmel: FBgn0030638, CG11655, [Score=154, Expect=2e-41]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=202, Expect=9e-59]} {Smed: dd_Smed_v6_11330_0_1, dd_Smed_v6_11330_0_1, [RH, Score=297, Expect=9e-96]} {RNA1509_41454} {RNA1310_15046, RNA1509_41454} {RNA1509_41454, RNA815_3102}
41. MligTC455_40620 3703 77.15 Mlig455_034547, Mlig455_064817

Neo: -

Age: logFC(26M/2M)=0.348

Region-enriched R3: 1.638/0.00022

 SGPL1 4.35 0.734 - 0.813 0.951 0.880 0.972

Mlig455_034547 {REF} {Length: 1975} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=71.4]; Aminotransferase class-V [PF00266.21, score=28.0]} {Human: ENSG00000166224, SGPL1, sphingosine-1-phosphate lyase 1, [Score=313, Expect=1e-99]} {Mouse: ENSMUSG00000020097, Sgpl1, sphingosine phosphate lyase 1, [Score=313, Expect=8e-100]} {Dmel: FBgn0010591, Sply, Sphingosine-1-phosphate lyase, [Score=286, Expect=9e-90]} {Celegans: WBGene00004981, spl-1, Sphingosine-1-phosphate lyase, [Score=283, Expect=2e-88]} {Smed: dd_Smed_v6_4459_0_1, dd_Smed_v6_4459_0_1, [Score=301, Expect=2e-95]} {RNA1509_16302} {RNA1310_14912} {RNA815_7513}

Mlig455_064817 {REF} {Length: 3062} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=73.9]; Aminotransferase class-V [PF00266.21, score=28.0]} {Human: ENSG00000166224, SGPL1, sphingosine-1-phosphate lyase 1, [Score=316, Expect=1e-100]} {Mouse: ENSMUSG00000020097, Sgpl1, sphingosine phosphate lyase 1, [Score=315, Expect=2e-100]} {Dmel: FBgn0010591, Sply, Sphingosine-1-phosphate lyase, [Score=283, Expect=1e-88]} {Celegans: WBGene00004981, spl-1, Sphingosine-1-phosphate lyase, [Score=286, Expect=1e-89]} {Smed: dd_Smed_v6_4459_0_1, dd_Smed_v6_4459_0_1, [Score=301, Expect=1e-95]} {RNA1509_12635, RNA1509_16302} {RNA1310_14912, RNA1509_12635, RNA1509_16302} {RNA1509_12635, RNA1509_16302, RNA815_7513}
42. MligTC455_19080 969 20.19 Mlig455_033341

Neo: -

Age: Up-Down-Down

Region-enriched R5: 1.378/0.02877

 4.325 0.902 0.733 - 0.986 0.880 0.824 Mlig455_033341 {REF} {Length: 1009} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_41133} {RNA1310_2059.1} {RNA815_20560.2}
43. MligTC455_49659 4741 98.77 Mlig455_011512, Mlig455_050003

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.314

Region-enriched R3: 1.923/0.00380

 4.308 0.955 0.807 - 0.924 0.714 0.908

Mlig455_011512 {REF} {Length: 2299} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}

Mlig455_050003 {REF} {Length: 1812} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}
44. MligTC455_34855 1221 25.44 Mlig455_062463

Neo: -

Age: logFC(26M/2M)=0.211

Region-enriched R4: 1.791/0.02708
Region-enriched R3: 1.675/0.02300

 CYP2J2 4.307 0.874 0.968 - 0.827 0.895 0.743 Mlig455_062463 {REF} {Length: 3167} {Pfam: Cytochrome P450 [PF00067.24, score=328.5]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=271, Expect=7e-85]} {Mouse: ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=4e-86]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=266, Expect=5e-83]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=263, Expect=1e-81]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=237, Expect=1e-71]} {Celegans: WBGene00018413, cyp-33C4, CYtochrome P450 family, [RH, Score=267, Expect=1e-83]} {Smed: dd_Smed_v6_2351_0_2, dd_Smed_v6_2351_0_2, [Score=269, Expect=2e-84]} {RNA1509_51219} {RNA1310_15059, RNA1509_51219} {RNA1509_51219, RNA815_5935.1}
45. MligTC455_42042 5653 117.77 Mlig455_011072

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.324

Region-enriched R3: 1.823/0.00256

 4.215 0.783 0.753 0.847 0.866 - 0.966 Mlig455_011072 {REF} {Length: 901} {Pfam: Lipocalin / cytosolic fatty-acid binding protein family [PF00061.25, score=22.3]; PRELI-like family [PF04707.16, score=19.8]} {RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378} {RNA1310_48326.1, RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378} {RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378, RNA815_23354}
46. MligTC455_39015 2149 44.77 Mlig455_039687, Mlig455_039743

Neo: -

Age: logFC(26M/2M)=1.265

Region-enriched R4: 1.730/0.03079

 4.122 0.797 0.768 - 0.989 0.769 0.799

Mlig455_039687 {REF} {Length: 939} {RNA1509_18179} {RNA1310_34151} {RNA815_37566}

Mlig455_039743 {REF} {Length: 939} {RNA1509_18179} {RNA1310_34151} {RNA815_37566}
47. MligTC455_43587 981 20.44 Mlig455_064849

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.445

Region-enriched R4: 1.141/0.04839

 4.104 0.709 - 0.758 0.863 0.958 0.816 Mlig455_064849 {REF} {Length: 1597} {RNA1509_13829} {RNA1310_22619, RNA1509_13829} {RNA1509_13829, RNA815_12635}
48. MligTC455_16017 1654 34.46 Mlig455_052747

Neo: -

Age: -

Region-enriched R4: 1.664/0.00032
Region-enriched R3: 1.084/0.03324

 PM20D2 4.077 0.759 0.879 0.769 - 0.714 0.956 Mlig455_052747 {REF} {Length: 1787} {TRANSSPLICED} {Pfam: Peptidase dimerisation domain [PF07687.16, score=33.3]; Peptidase family M20/M25/M40 [PF01546.30, score=29.9]} {Human: ENSG00000146281, PM20D2, peptidase M20 domain containing 2, [RH, Score=356, Expect=5e-120]} {Mouse: ENSMUSG00000054659, Pm20d2, peptidase M20 domain containing 2, [RH, Score=355, Expect=1e-119]} {Smed: dd_Smed_v6_7395_0_1, dd_Smed_v6_7395_0_1, [RH, Score=337, Expect=9e-114]} {RNA1509_27696, RNA1509_38773, RNA1509_53331} {RNA1310_17432.1, RNA1509_27696, RNA1509_38773, RNA1509_53331} {RNA1509_27696, RNA1509_38773, RNA1509_53331, RNA815_6952}
49. MligTC455_45464 977 20.36 Mlig455_031625, Mlig455_048204

Neo: -

Age: logFC(26M/2M)=-0.328

Region-enriched R4: 3.768/0.00000
Region-enriched R5: 2.629/0.00008
Region-enriched R3: 2.062/0.02213

 4.077 - 0.804 0.761 0.829 0.950 0.733

Mlig455_031625 {REF} {Length: 1443} {Pfam: PDZ domain [PF17820.3, score=36.8]; PDZ domain [PF00595.26, score=33.3]; PDZ domain [PF13180.8, score=31.7]} {RNA1509_31272, RNA1509_39340} {RNA1310_26900, RNA1509_31272, RNA1509_39340} {RNA1509_31272, RNA1509_39340, RNA815_10356}

Mlig455_048204 {REF} {Length: 1436} {Pfam: PDZ domain [PF17820.3, score=36.8]; PDZ domain [PF00595.26, score=33.3]; PDZ domain [PF13180.8, score=31.7]} {RNA1509_31272} {RNA1310_26900} {RNA815_10356}
50. MligTC455_24859 5590 116.45 Mlig455_054066, Mlig455_063284

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.306

Region-enriched R3: 2.202/0.00434

 4.053 0.963 0.835 0.718 0.717 - 0.820

Mlig455_054066 {REF} {Length: 1406} {RNA1509_33411, RNA1509_7753} {RNA1310_22791, RNA1509_33411} {RNA1509_33411, RNA815_10514.1}

Mlig455_063284 {REF} {Length: 1414} {Pfam: Multi-glycosylated core protein 24 (MGC-24), sialomucin [PF05283.13, score=46.5]} {Mouse: ENSMUSG00000050912, Tmem123, transmembrane protein 123, [Score=46.6, Expect=2e-06]} {Dmel: FBgn0045823, vsg, visgun, [Score=53.1, Expect=8e-09]} {Smed: dd_Smed_v6_828_0_1, dd_Smed_v6_828_0_1, [RH, Score=53.5, Expect=2e-10]} {RNA1509_7753} {RNA1310_22791} {RNA815_10514.1}
51. MligTC455_46181 2902 60.45 Mlig455_054291

Neo: -

Age: logFC(26M/2M)=-0.282

Region-enriched R4: 1.689/0.00164
Region-enriched R3: 1.207/0.03875
Region-enriched R5: 1.162/0.01606

 3.667 - - 0.934 0.982 0.870 0.881 Mlig455_054291 {REF} {Length: 934} {Pfam: Universal stress protein family [PF00582.28, score=107.5]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=119, Expect=8e-35]} {RNA1509_5080} {RNA1310_45709, RNA1509_5080} {RNA1509_5080, RNA815_23470}
52. MligTC455_36664 2276 47.42 Mlig455_005884

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.400

Region-enriched R3: 1.625/0.01190

 PSAP 3.611 - 0.903 - 0.984 0.894 0.830 Mlig455_005884 {REF} {Length: 3972} {Pfam: Saposin-like type B, region 1 [PF05184.17, score=380.3]; Saposin-like type B, region 2 [PF03489.19, score=358.9]; Homeodomain-like domain [PF13384.8, score=54.4]; Helix-turn-helix domain [PF13518.8, score=42.8]; Saposin A-type domain [PF02199.17, score=33.9]; Protein of unknown function (DUF2753) [PF10952.10, score=33.0]; Replication factor RFC1 C terminal domain [PF08519.14, score=29.4]; Winged helix-turn helix [PF13551.8, score=25.9]; HD domain [PF13023.8, score=24.1]; Putative transmembrane protein [PF10271.11, score=24.0]; Delta endotoxin [PF18449.3, score=20.2]; DNA replication factor Cdt1 C-terminal domain [PF16679.7, score=19.5]} {Human: ENSG00000197746, PSAP, prosaposin, [RH, Score=184, Expect=6e-49]} {Mouse: ENSMUSG00000004207, Psap, prosaposin, [RH, Score=162, Expect=1e-41]} {Dmel: FBgn0000416, Sap-r, Saposin-related, [RH, Score=237, Expect=2e-64]} {Smed: dd_Smed_v6_266_0_1, dd_Smed_v6_266_0_1, [Score=97.8, Expect=2e-22]} {RNA1509_1917} {RNA1310_3003.1} {RNA815_5033.1}
53. MligTC455_35652 9154 190.71 Mlig455_057115

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.261

Region-enriched R3: 1.585/0.00213
Region-enriched R5: 1.102/0.03479

 CD82 3.571 0.761 - - 0.900 0.942 0.968 Mlig455_057115 {REF} {Length: 1682} {Pfam: Tetraspanin family [PF00335.22, score=118.2]} {Human: ENSG00000085117, CD82, CD82 molecule, [Score=68.9, Expect=5e-13]} {Mouse: ENSMUSG00000030342, Cd9, CD9 antigen, [Score=73.2, Expect=7e-15]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [RH, Score=110, Expect=3e-28]} {Celegans: WBGene00006634, tsp-8, Tetraspanin, [Score=56.2, Expect=5e-09]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [Score=97.1, Expect=1e-23]} {RNA1509_13954, RNA1509_2691, RNA1509_27048, RNA1509_4769, RNA1509_58598, RNA1509_58951, RNA1509_9364, RNA1509_9911} {RNA1310_22327, RNA1509_13954, RNA1509_2691, RNA1509_27048, RNA1509_4769, RNA1509_58598, RNA1509_58951, RNA1509_9364, RNA1509_9911} {RNA1509_13954, RNA1509_2691, RNA1509_27048, RNA1509_4769, RNA1509_58598, RNA1509_58951, RNA1509_9364, RNA1509_9911, RNA815_10761}
54. MligTC455_37016 2907 60.56 Mlig455_024229

Neo: -

Age: Down-Up-Down

Region-enriched R3: 2.174/0.00004

 3.471 0.841 - - 0.968 0.810 0.852 Mlig455_024229 {REF} {Length: 1688} {RNA1509_25840, RNA1509_36713, RNA1509_3844, RNA1509_6102} {RNA1310_12542.1, RNA1509_25840, RNA1509_36713, RNA1509_3844, RNA1509_6102} {RNA1509_25840, RNA1509_36713, RNA1509_3844, RNA1509_6102, RNA815_670}
55. MligTC455_26632 2223 46.31 Mlig455_010979

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.932

Region-enriched R3: 1.352/0.01651

 ASGR2 3.355 0.809 - - 0.881 0.703 0.962 Mlig455_010979 {REF} {Length: 3718} {Pfam: Lectin C-type domain [PF00059.23, score=51.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=29.4]} {Human: ENSG00000161944, ASGR2, asialoglycoprotein receptor 2, [Score=53.1, Expect=6e-07]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=62.0, Expect=2e-09]; ENSMUSG00000020695, Mrc2, mannose receptor, C type 2, [Score=60.5, Expect=6e-09]} {Dmel: FBgn0029697, CG15570, [Score=82.4, Expect=7e-16]} {Celegans: WBGene00020585, clec-178, C-type LECtin, [Score=57.4, Expect=2e-09]} {Smed: dd_Smed_v6_1489_0_1, dd_Smed_v6_1489_0_1, [Score=48.5, Expect=7e-06]} {RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412} {RNA1310_25013.1, RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412} {RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412, RNA815_11727}
56. MligTC455_14276 2183 45.48 Mlig455_065037

Neo: -

Age: logFC(26M/2M)=0.489

 PLBD1 3.298 0.740 - - 0.977 0.848 0.733 Mlig455_065037 {REF} {Length: 2884} {Pfam: Phospholipase B [PF04916.15, score=514.0]} {Human: ENSG00000121316, PLBD1, phospholipase B domain containing 1, [RH, Score=462, Expect=1e-156]} {Mouse: ENSMUSG00000030214, Plbd1, phospholipase B domain containing 1, [RH, Score=478, Expect=2e-163]} {Dmel: FBgn0016031, lama, lamina ancestor, [Score=92.0, Expect=4e-19]} {Celegans: WBGene00008607, F09B12.3, Putative phospholipase B-like 2, [RH, Score=236, Expect=1e-69]} {Smed: dd_Smed_v6_485_0_1, dd_Smed_v6_485_0_1, [Score=209, Expect=7e-60]} {RNA1509_9263} {RNA1310_7896, RNA1509_9263} {RNA1509_9263, RNA815_2504}
57. MligTC455_50449 2354 49.04 Mlig455_064469

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.266

Region-enriched R3: 1.639/0.00084
Region-enriched R5: 1.149/0.01827

 KREMEN1 3.23 0.820 - 0.741 0.717 - 0.952 Mlig455_064469 {REF} {Length: 719} {TRANSSPLICED} {Pfam: WSC domain [PF01822.21, score=61.7]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=52.4, Expect=9e-08]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=50.8, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.9, Expect=1e-08]} {RNA1509_25081, RNA1509_3423, RNA1509_43914, RNA1509_47774, RNA1509_51348} {RNA1310_56240.1, RNA1509_25081, RNA1509_3423, RNA1509_43914, RNA1509_47774} {RNA1509_25081, RNA1509_3423, RNA1509_43914, RNA1509_47774, RNA815_26405}
58. MligTC455_53724 3456 72 Mlig455_018433

Neo: -

Age: -

Region-enriched R3: 1.982/0.00002
Region-enriched R4: 1.264/0.03136

 LCT 2.785 - - - 0.888 0.920 0.977 Mlig455_018433 {REF} {Length: 2252} {Pfam: Glycosyl hydrolase family 1 [PF00232.20, score=486.8]} {Human: ENSG00000115850, LCT, lactase, [Score=398, Expect=3e-123]; ENSG00000188501, LCTL, lactase like, [Score=381, Expect=3e-126]} {Mouse: ENSMUSG00000026354, Lct, lactase, [Score=392, Expect=4e-121]; ENSMUSG00000032401, Lctl, lactase-like, [Score=373, Expect=2e-123]} {Dmel: FBgn0036659, CG9701, [Score=362, Expect=1e-119]} {Celegans: WBGene00016848, klo-1, KLOtho (Mammalian aging-associated protein) homolog, [Score=290, Expect=1e-92]} {RNA1509_43625, RNA1509_50349, RNA1509_58520} {RNA1310_27605, RNA1509_50349, RNA1509_58520} {RNA1509_50349, RNA1509_58520, RNA815_3875.2}
59. MligTC455_35217 5138 107.05 Mlig455_014282, Mlig455_014335

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.399

Region-enriched R3: 1.348/0.01129

 2.711 0.957 - - 0.862 - 0.892

Mlig455_014282 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=158.0]} {RNA1509_22501, RNA1509_4768} {RNA1310_7742.1, RNA1509_22501} {RNA1509_22501, RNA815_6411}

Mlig455_014335 {REF} {Length: 1769} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=159.5]} {RNA1509_4768} {RNA1310_7742.1} {RNA815_6411}
60. MligTC455_42438 2020 42.09 Mlig455_055199, Mlig455_055244

Neo: -

Age: -

Region-enriched R3: 2.265/0.00232

 2.563 0.832 0.957 - - - 0.774

Mlig455_055199 {REF} {Length: 6274} {Pfam: Pyruvate phosphate dikinase, AMP/ATP-binding domain [PF01326.21, score=226.3]; PEP-utilising enzyme, mobile domain [PF00391.25, score=75.8]} {Dmel: FBgn0040342, CG3706, [RH, Score=132, Expect=4e-32]} {Celegans: WBGene00011893, T21C9.6, [RH, Score=307, Expect=3e-86]} {Smed: dd_Smed_v6_2604_0_1, dd_Smed_v6_2604_0_1, [RH, Score=855, Expect=0.0]} {RNA1509_1405, RNA1509_6581} {RNA1310_1331, RNA1509_6581} {RNA1509_6581, RNA815_563}

Mlig455_055244 {REF} {Length: 5074} {Pfam: Pyruvate phosphate dikinase, AMP/ATP-binding domain [PF01326.21, score=202.1]} {Dmel: FBgn0040342, CG3706, [RH, Score=132, Expect=8e-33]} {Celegans: WBGene00011893, T21C9.6, [Score=155, Expect=7e-39]} {Smed: dd_Smed_v6_2604_0_1, dd_Smed_v6_2604_0_1, [Score=466, Expect=1e-147]} {RNA1509_1405} {RNA1310_1331} {RNA815_563}
61. MligTC455_42935 9858 205.38 Mlig455_001377

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.269

Region-enriched R4: 1.115/0.00000

 ATP5MC2 2.54 0.828 - - 0.953 - 0.759 Mlig455_001377 {REF} {Length: 750} {TRANSSPLICED} {Pfam: ATP synthase subunit C [PF00137.23, score=42.6]} {Human: ENSG00000135390, ATP5MC2, ATP synthase membrane subunit c locus 2, [RH, Score=147, Expect=3e-46]; ENSG00000154518, ATP5MC3, ATP synthase membrane subunit c locus 3, [RH, Score=144, Expect=6e-45]; ENSG00000159199, ATP5MC1, ATP synthase membrane subunit c locus 1, [RH, Score=143, Expect=5e-45]} {Mouse: ENSMUSG00000062683, Atp5g2, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9), [RH, Score=147, Expect=2e-46]; ENSMUSG00000018770, Atp5g3, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9), [RH, Score=142, Expect=2e-44]} {Dmel: FBgn0039830, ATPsynC, ATP synthase, subunit C, [RH, Score=147, Expect=2e-46]} {Celegans: WBGene00022336, Y82E9BR.3, ATP synthase lipid-binding protein, mitochondrial, [RH, Score=148, Expect=3e-47]} {Smed: dd_Smed_v6_401_0_1, dd_Smed_v6_401_0_1, [RH, Score=118, Expect=1e-35]} {RNA1509_1652, RNA1509_30579, RNA1509_3146, RNA1509_4539, RNA1509_58433} {RNA1310_47479, RNA1509_1652, RNA1509_30579, RNA1509_3146, RNA1509_4539, RNA1509_58433} {RNA1509_1652, RNA1509_30579, RNA1509_3146, RNA1509_4539, RNA1509_58433, RNA815_11384.2}
62. MligTC455_46553 1388 28.92 Mlig455_047459

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=1.470

 DHCR24 2.428 - 0.706 - 0.960 0.762 - Mlig455_047459 {REF} {Length: 2061} {Pfam: FAD binding domain [PF01565.25, score=49.8]} {Human: ENSG00000116133, DHCR24, 24-dehydrocholesterol reductase, [RH, Score=649, Expect=0.0]} {Mouse: ENSMUSG00000034926, Dhcr24, 24-dehydrocholesterol reductase, [RH, Score=643, Expect=0.0]} {Celegans: WBGene00018718, F52H2.6, Diminuto-like protein, [RH, Score=498, Expect=4e-173]} {Smed: dd_Smed_v6_13164_0_1, dd_Smed_v6_13164_0_1, [RH, Score=629, Expect=0.0]} {RNA1509_54118, RNA1509_5458, RNA1509_59230} {RNA1310_12391.1, RNA1509_54118, RNA1509_5458, RNA1509_59230} {RNA1509_54118, RNA1509_5458, RNA1509_59230, RNA815_5116}
63. MligTC455_18980 2453 51.11 Mlig455_051123

Neo: -

Age: logFC(26M/2M)=-0.250

 TSPAN6 1.722 - - - 0.966 - 0.756 Mlig455_051123 {REF} {Length: 2220} {Pfam: Tetraspanin family [PF00335.22, score=103.8]} {Human: ENSG00000000003, TSPAN6, tetraspanin 6, [Score=67.8, Expect=1e-12]} {Mouse: ENSMUSG00000028699, Tspan1, tetraspanin 1, [Score=69.3, Expect=2e-13]} {Dmel: FBgn0027865, Tsp96F, Tetraspanin 96F, [Score=60.5, Expect=3e-10]} {Celegans: WBGene00006643, tsp-17, TetraSPanin family, [Score=70.1, Expect=9e-14]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [Score=93.6, Expect=3e-22]} {RNA1509_30747, RNA1509_8575, RNA1509_9121} {RNA1310_961, RNA1509_30747, RNA1509_8575, RNA1509_9121} {RNA1509_30747, RNA1509_8575, RNA1509_9121, RNA815_10076}
64. MligTC455_15677 13390 278.96 Mlig455_044839

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.437

Region-enriched R3: 1.329/0.00066

 MOXD1 1.708 0.750 - - 0.958 - - Mlig455_044839 {REF} {Length: 2629} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=85.8]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=61.6]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=112, Expect=2e-25]; ENSG00000123454, DBH, dopamine beta-hydroxylase, [Score=110, Expect=1e-24]} {Mouse: ENSMUSG00000000889, Dbh, dopamine beta hydroxylase, [Score=114, Expect=3e-26]; ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=114, Expect=3e-26]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=128, Expect=7e-31]} {Celegans: WBGene00006541, tbh-1, Tyramine beta-hydroxylase, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_42610_0_1, dd_Smed_v6_42610_0_1, [Score=121, Expect=6e-30]} {RNA1509_1048, RNA1509_22995, RNA1509_2300, RNA1509_25012, RNA1509_5451, RNA1509_893} {RNA1310_10153.1, RNA1509_1048, RNA1509_22995, RNA1509_2300, RNA1509_25012, RNA1509_5451} {RNA1509_1048, RNA1509_22995, RNA1509_2300, RNA1509_25012, RNA1509_5451, RNA815_3379.1}
65. MligTC455_43165 376 7.84 Mlig455_039957

Neo: -

Age: -

Region-enriched R3: 1.989/0.00104
Region-enriched R5: 1.524/0.00587

 1.674 0.967 - - 0.707 - - Mlig455_039957 {REF} {Length: 758} {RNA1509_47183, RNA1509_51167, RNA1509_8939} {RNA1310_10828, RNA1509_47183, RNA1509_51167} {RNA1509_47183, RNA1509_51167, RNA815_7128}
66. MligTC455_26964 11038 229.96 Mlig455_042220

Neo: Germline

Age: -

 P4HB 0.95 - - - - 0.950 - Mlig455_042220 {REF} {Length: 3004} {Pfam: Thioredoxin-like domain [PF13848.8, score=53.4]; ERp29, N-terminal domain [PF07912.15, score=27.6]; Thioredoxin [PF00085.22, score=25.0]} {Human: ENSG00000185624, P4HB, prolyl 4-hydroxylase subunit beta, [Score=177, Expect=1e-55]} {Mouse: ENSMUSG00000025130, P4hb, prolyl 4-hydroxylase, beta polypeptide, [Score=176, Expect=4e-53]} {Dmel: FBgn0014002, Pdi, Protein disulfide isomerase, [Score=128, Expect=3e-35]} {Celegans: WBGene00003963, pdi-2, Protein disulfide-isomerase 2, [Score=184, Expect=6e-57]} {Smed: dd_Smed_v6_250_0_1, dd_Smed_v6_250_0_1, [Score=162, Expect=2e-48]} {RNA1509_1575} {RNA1310_2450.1} {RNA815_1453.1}
67. MligTC455_52809 228 4.75 Mlig455_031250

Neo: -

Age: -

Region-enriched R5: 3.073/0.00003

 RAD51 0.95 - - - - 0.950 - Mlig455_031250 {REF} {Length: 1864} {Pfam: Rad51 [PF08423.13, score=244.5]; Helix-hairpin-helix domain [PF14520.8, score=24.4]} {Human: ENSG00000051180, RAD51, RAD51 recombinase, [Score=343, Expect=4e-118]} {Mouse: ENSMUSG00000027323, Rad51, RAD51 recombinase, [Score=342, Expect=5e-118]} {Dmel: FBgn0003479, spn-A, spindle A, [Score=253, Expect=3e-83]} {Celegans: WBGene00004297, rad-51, RAD51 short isoform; RecA/Rad51/Dmc1-like protein, [Score=240, Expect=5e-78]} {Smed: dd_Smed_v6_8626_0_1, dd_Smed_v6_8626_0_1, [Score=288, Expect=2e-98]} {RNA1509_10251} {RNA1310_22466} {RNA815_9671}

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