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Results for MligTC455_27191

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_27191 87 1.81 Mlig455_069613

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.833

Region-enriched R2: 4.460/0.00883

RNF213 Mlig455_069613 {REF} {Length: 9312} {Pfam: AAA domain (dynein-related subfamily) [PF07728.16, score=52.4]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=48.5]; P-loop containing dynein motor region [PF12775.9, score=35.6]; Sigma-54 interaction domain [PF14532.8, score=23.5]; AAA ATPase domain [PF13191.8, score=22.0]; ATPase domain predominantly from Archaea [PF01637.20, score=21.6]; ABC transporter [PF00005.29, score=20.0]; AAA domain [PF13401.8, score=19.1]} {Human: ENSG00000173821, RNF213, ring finger protein 213, [Score=402, Expect=1e-111]} {Mouse: ENSMUSG00000070327, Rnf213, ring finger protein 213, [Score=380, Expect=6e-105]} {RNA1509_3638, RNA1509_52214} {RNA1310_14.1, RNA1509_52214} {RNA1509_52214, RNA815_16.1}

Cumulative graph for MligTC455_27191

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -8.119 1.935 0.03190 0.45365
RegionR2 4.46 1.935 0.00029 0.00883
RegionR3 1.404 1.935 0.20947 0.75087
RegionR4 -2.341 1.935 0.99951 1.00000
RegionR5 -1.166 1.935 0.99360 1.00000
RegionR6 0.91 1.935 0.44827 1.00000
RegionR7 1.774 1.935 0.20284 0.81178
RegionR8 3.079 1.935 0.04288 0.40597

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 2.687 1.935 0.99984 1.00000
RegenerationR2 -1.118 1.935 0.20372 0.65044
RegenerationR3 -1.411 1.935 0.20601 0.64106
RegenerationR4 -2.374 1.935 0.04593 0.34614
RegenerationR5 -0.602 1.935 0.48687 0.85062
RegenerationR6 -0.632 1.935 0.53841 0.83200
RegenerationBL -6.393 1.935 0.00920 0.09576
RegenerationTP -5.618 1.935 0.01397 0.20232


Genes with expression patterns similar to MligTC455_27191

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_27191 87 1.81 Mlig455_069613

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.833

Region-enriched R2: 4.460/0.00883

RNF213 4 1.000 1.000 1.000 - 1.000 - Mlig455_069613 {REF} {Length: 9312} {Pfam: AAA domain (dynein-related subfamily) [PF07728.16, score=52.4]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=48.5]; P-loop containing dynein motor region [PF12775.9, score=35.6]; Sigma-54 interaction domain [PF14532.8, score=23.5]; AAA ATPase domain [PF13191.8, score=22.0]; ATPase domain predominantly from Archaea [PF01637.20, score=21.6]; ABC transporter [PF00005.29, score=20.0]; AAA domain [PF13401.8, score=19.1]} {Human: ENSG00000173821, RNF213, ring finger protein 213, [Score=402, Expect=1e-111]} {Mouse: ENSMUSG00000070327, Rnf213, ring finger protein 213, [Score=380, Expect=6e-105]} {RNA1509_3638, RNA1509_52214} {RNA1310_14.1, RNA1509_52214} {RNA1509_52214, RNA815_16.1}
2. MligTC455_16148 198 4.12 Mlig455_057689

Neo: -

Age: -

KLHDC8A 2.477 - 0.728 0.789 - 0.960 - Mlig455_057689 {REF} {Length: 1806} {Pfam: Kelch motif [PF13964.8, score=56.9]; Kelch motif [PF01344.27, score=52.7]; Kelch motif [PF07646.17, score=37.5]; Galactose oxidase, central domain [PF13418.8, score=35.1]; Kelch motif [PF13854.8, score=27.6]} {Human: ENSG00000162873, KLHDC8A, kelch domain containing 8A, [Score=58.5, Expect=2e-09]} {Mouse: ENSMUSG00000042115, Klhdc8a, kelch domain containing 8A, [Score=63.9, Expect=1e-10]} {Smed: dd_Smed_v6_14507_0_1, dd_Smed_v6_14507_0_1, [RH, Score=209, Expect=4e-63]} {RNA1509_58319} {RNA1310_20213} {RNA815_8052}
3. MligTC455_29073 88 1.84 Mlig455_029132, Mlig455_040198

Neo: -

Age: -

1.751 0.798 - - - 0.953 -

Mlig455_029132 {REF} {Length: 2937} {NoTransDecoderORF} {RNA1509_45811} {RNA1310_50362} {RNA815_3257.3}

Mlig455_040198 {REF} {Length: 1035} {NoTransDecoderORF} {RNA1509_25000} {RNA1310_4307.1} {RNA815_2326}
4. MligTC455_54034 260 5.41 Mlig455_017202

Neo: -

Age: -

Region-enriched R8: 2.476/0.02915

CALML3 1.739 0.785 - - - 0.954 - Mlig455_017202 {REF} {Length: 1789} {Pfam: EF hand [PF00036.34, score=86.0]; EF-hand domain pair [PF13499.8, score=75.1]; EF hand [PF13202.8, score=71.2]; EF-hand domain [PF13405.8, score=67.8]; EF-hand domain pair [PF13833.8, score=53.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=19.0]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=82.8, Expect=1e-20]; ENSG00000198668, CALM1, calmodulin 1, [Score=79.7, Expect=2e-19]; ENSG00000160014, CALM3, calmodulin 3, [Score=79.7, Expect=2e-19]; ENSG00000143933, CALM2, calmodulin 2, [Score=79.7, Expect=2e-19]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=81.6, Expect=3e-20]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=79.7, Expect=1e-19]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=79.7, Expect=1e-19]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=79.7, Expect=1e-19]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=77.8, Expect=6e-19]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=77.8, Expect=5e-19]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=77.8, Expect=4e-19]} {RNA1509_40737} {RNA1310_63281, RNA1509_40737} {RNA1509_40737, RNA815_19875}
5. MligTC455_13773 101 2.1 Mlig455_010827

Neo: -

Age: -

0.966 - - - - 0.966 - Mlig455_010827 {REF} {Length: 304} {NoTransDecoderORF} {RNA1509_22845} {RNA1310_11632} {RNA815_10000}
6. MligTC455_30177 188 3.91 Mlig455_046030, Mlig455_055304

Neo: -

Age: logFC(26M/2M)=0.649

MAP3K4 0.966 - - 0.966 - - -

Mlig455_046030 {REF} {Length: 2487} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=31.6]; Ankyrin repeats (many copies) [PF13637.8, score=29.2]; Ankyrin repeat [PF13606.8, score=25.1]; Ankyrin repeat [PF00023.32, score=23.0]; Ankyrin repeats (many copies) [PF13857.8, score=22.6]} {RNA1509_38221} {RNA1310_31472} {RNA815_6977.1}

Mlig455_055304 {REF} {Length: 3739} {Pfam: Protein kinase domain [PF00069.27, score=161.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=116.9]; Ankyrin repeats (3 copies) [PF12796.9, score=78.6]; Ankyrin repeat [PF13606.8, score=52.4]; Ankyrin repeats (many copies) [PF13637.8, score=51.0]; Ankyrin repeats (many copies) [PF13857.8, score=49.9]; Ankyrin repeat [PF00023.32, score=45.3]; Fungal protein kinase [PF17667.3, score=23.9]; ABC1 atypical kinase-like domain [PF03109.18, score=19.1]; Phosphotransferase enzyme family [PF01636.25, score=18.6]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=132, Expect=6e-31]; ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=131, Expect=1e-31]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=130, Expect=1e-31]; ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=127, Expect=9e-30]} {Dmel: FBgn0024329, Mekk1, [Score=122, Expect=3e-28]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=129, Expect=1e-30]} {Smed: dd_Smed_v6_2030_0_13, dd_Smed_v6_2030_0_13, [Score=118, Expect=3e-28]} {RNA1509_38221} {RNA1310_10050, RNA1509_38221} {RNA1509_38221, RNA815_9449.1}
7. MligTC455_35046 485 10.1 Mlig455_067666

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.340

Region-enriched R8: 2.605/0.02555
Region-enriched R2: 2.499/0.01493

PDE2A 0.964 - - - - 0.964 - Mlig455_067666 {REF} {Length: 5187} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=237.1]; GAF domain [PF01590.28, score=63.4]; GAF domain [PF13492.8, score=25.2]} {Human: ENSG00000186642, PDE2A, phosphodiesterase 2A, [RH, Score=718, Expect=0.0]} {Mouse: ENSMUSG00000030653, Gm45837, predicted gene 45837, [RH, Score=713, Expect=0.0]; ENSMUSG00000110195, Pde2a, phosphodiesterase 2A, cGMP-stimulated, [RH, Score=713, Expect=0.0]} {Dmel: FBgn0085370, Pde11, Phosphodiesterase 11, [Score=325, Expect=2e-95]} {Celegans: WBGene00011146, pde-2, Probable 3',5'-cyclic phosphodiesterase pde-2, [RH, Score=334, Expect=7e-101]} {Smed: dd_Smed_v6_8589_0_2, dd_Smed_v6_8589_0_2, [RH, Score=817, Expect=0.0]} {RNA1509_5437} {RNA1310_2713.4} {RNA815_1901.1}
8. MligTC455_27372 49 1.02 Mlig455_036854

Neo: -

Age: -

ANK2 0.963 - - - - 0.963 - Mlig455_036854 {REF} {Length: 4696} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=152.6]; Ankyrin repeat [PF00023.32, score=108.0]; Ankyrin repeats (many copies) [PF13637.8, score=100.4]; Ankyrin repeat [PF13606.8, score=84.9]; Ankyrin repeats (many copies) [PF13857.8, score=82.8]; Mab-21 protein [PF03281.16, score=26.1]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=148, Expect=3e-35]; ENSG00000151150, ANK3, ankyrin 3, [Score=145, Expect=2e-34]; ENSG00000029534, ANK1, ankyrin 1, [Score=144, Expect=7e-34]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=143, Expect=9e-34]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=139, Expect=2e-32]; ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=136, Expect=1e-31]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=150, Expect=3e-36]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=143, Expect=5e-34]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=157, Expect=1e-38]} {RNA1509_49840} {RNA1310_35067, RNA1509_49840} {RNA1509_49840, RNA815_2400.1}
9. MligTC455_33143 37 0.77 Mlig455_008293

Neo: -

Age: Down-Down-Up

Regeneration-upregulated R2: 5.573

Regeneration-enriched R2: 5.573

NPHS1 0.963 - - - - 0.963 - Mlig455_008293 {REF} {Length: 4631} {Pfam: Immunoglobulin domain [PF13927.8, score=123.9]; Immunoglobulin I-set domain [PF07679.18, score=85.0]; Immunoglobulin domain [PF13895.8, score=73.9]; Immunoglobulin domain [PF00047.27, score=56.6]; Immunoglobulin V-set domain [PF07686.19, score=38.3]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=24.8]} {Human: ENSG00000161270, NPHS1, NPHS1, nephrin, [Score=74.7, Expect=1e-12]} {Mouse: ENSMUSG00000022762, Ncam2, neural cell adhesion molecule 2, [Score=82.8, Expect=2e-15]} {Dmel: FBgn0029082, hbs, hibris, [Score=127, Expect=5e-29]} {Celegans: WBGene00018215, igcm-1, ImmunoGlobulin-like Cell adhesion Molecule family, [Score=63.2, Expect=1e-09]} {Smed: dd_Smed_v6_16056_0_1, dd_Smed_v6_16056_0_1, [Score=76.3, Expect=1e-13]} {RNA1509_15216} {RNA1310_1630} {RNA815_12733}
10. MligTC455_13329 95 1.98 Mlig455_009198

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.124

0.958 - - - - 0.958 - Mlig455_009198 {REF} {Length: 2007} {RNA1509_22077, RNA1509_32545} {RNA1310_29047.1, RNA1509_22077, RNA1509_32545} {RNA1509_22077, RNA1509_32545, RNA815_17550}
11. MligTC455_16305 45 0.93 Mlig455_005717

Neo: -

Age: -

0.958 - - - - 0.958 - Mlig455_005717 {REF} {Length: 1504} {Pfam: Protein of unknown function (DUF4532) [PF15046.8, score=28.1]} {RNA1310_54208} {RNA815_57875}
12. MligTC455_08700 37 0.77 Mlig455_031782

Neo: -

Age: Up-Down-Down

0.954 - - - - 0.954 - Mlig455_031782 {REF} {Length: 2366} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_51813, RNA1509_6571} {RNA1310_585.1, RNA1509_51813, RNA1509_6571} {RNA1509_51813, RNA1509_6571, RNA815_122.1}
13. MligTC455_38859 28 0.59 Mlig455_071137

Neo: -

Age: -

0.953 - - - - 0.953 - Mlig455_071137 {REF} {Length: 409} {NoTransDecoderORF} {RNA1509_22707} {RNA1310_90313} {RNA815_24119.1}
14. MligTC455_09059 61 1.27 Mlig455_023612, Mlig455_033807

Neo: -

Age: -

0.951 - - - - 0.951 -

Mlig455_023612 {REF} {Length: 346} {NoTransDecoderORF} {RNA1509_57341} {RNA1310_49037} {RNA815_24538}

Mlig455_033807 {REF} {Length: 314} {NoTransDecoderORF} {RNA1509_43209} {RNA1310_49037} {RNA815_24538}
15. MligTC455_24630 962 20.04 Mlig455_067759

Neo: -

Age: -

0.95 - - - - 0.950 - Mlig455_067759 {REF} {Length: 5477} {Pfam: RhoGEF domain [PF00621.22, score=30.3]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=21.0]} {RNA1509_7176} {RNA1310_1343.1} {RNA815_2798}
16. MligTC455_46324 175 3.66 Mlig455_056638

Neo: -

Age: -

PAM 0.95 - - - - 0.950 - Mlig455_056638 {REF} {Length: 4766} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=52.9]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=52.6]} {Human: ENSG00000145730, PAM, peptidylglycine alpha-amidating monooxygenase, [Score=105, Expect=1e-23]} {Mouse: ENSMUSG00000026335, Pam, peptidylglycine alpha-amidating monooxygenase, [Score=102, Expect=6e-23]} {Dmel: FBgn0283509, Phm, Peptidylglycine-alpha-hydroxylating monooxygenase, [Score=108, Expect=3e-26]} {Celegans: WBGene00022144, pghm-1, Probable peptidylglycine alpha-hydroxylating monooxygenase 1, [Score=88.6, Expect=2e-19]} {Smed: dd_Smed_v6_2646_0_1, dd_Smed_v6_2646_0_1, [Score=118, Expect=1e-29]} {RNA1509_54159} {RNA1310_19370, RNA1509_54159} {RNA1509_54159, RNA815_7199}

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