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Results for MligTC455_27835

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_27835 1363 28.40 Mlig455_048346

Neo: -

Age: -

Region-enriched R5: 1.320/0.00621

Regeneration-upregulated BL: 1.968

Regeneration-enriched BL: 1.968

 OPLAH Mlig455_048346 {REF} {Length: 14868} {TRANSSPLICED} {Pfam: Hydantoinase B/oxoprolinase [PF02538.16, score=677.6]; Hydantoinase/oxoprolinase [PF01968.20, score=348.4]; Hydantoinase/oxoprolinase N-terminal region [PF05378.15, score=172.3]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=128.4]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=113.3]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=76.9]; Integrase zinc binding domain [PF17921.3, score=68.9]; Aspartyl protease [PF13650.8, score=38.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=35.2]; Hydantoinase/oxoprolinase C-terminal domain [PF19278.1, score=25.9]; Retroviral aspartyl protease [PF00077.22, score=24.3]; Aspartyl protease [PF09668.12, score=23.4]; Putative peptidase (DUF1758) [PF05585.14, score=21.1]} {Human: ENSG00000178814, OPLAH, 5-oxoprolinase, ATP-hydrolysing, [Score=800, Expect=0.0]} {Mouse: ENSMUSG00000022562, Oplah, 5-oxoprolinase (ATP-hydrolysing), [Score=779, Expect=0.0]} {Dmel: FBgn0034733, CG4752, [Score=757, Expect=0.0]} {Celegans: WBGene00021430, Y38F2AR.12, [Score=763, Expect=0.0]} {Smed: dd_Smed_v6_5008_0_1, dd_Smed_v6_5008_0_1, [Score=847, Expect=0.0]} {RNA1509_20493} {RNA1310_131.1} {RNA815_52.1}

Cumulative graph for MligTC455_27835

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -2.438 5.127 0.05064 0.53010
RegionR2 0.53 5.127 0.34344 0.73579
RegionR3 1.288 5.127 0.00225 0.05438
RegionR4 0.926 5.127 0.04663 0.18401
RegionR5 1.32 5.127 0.00053 0.00621
RegionR6 1.108 5.127 0.01136 0.18188
RegionR7 -0.769 5.127 0.22436 0.84576
RegionR8 -1.966 5.127 0.03091 0.34384

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.156 5.127 0.54380 1.00000
RegenerationR2 1.109 5.127 0.01354 0.19019
RegenerationR3 0.731 5.127 0.11651 0.53228
RegenerationR4 0.595 5.127 0.22316 0.67120
RegenerationR5 0.683 5.127 0.12531 0.52860
RegenerationR6 0.972 5.127 0.03552 0.23613
RegenerationBL 1.968 5.127 0.00021 0.00765 Specific for BL: 1.968
RegenerationTP 2.059 5.127 0.00209 0.07392


Genes with expression patterns similar to MligTC455_27835

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_27835 1363 28.4 Mlig455_048346

Neo: -

Age: -

Region-enriched R5: 1.320/0.00621

Regeneration-upregulated BL: 1.968

Regeneration-enriched BL: 1.968

 OPLAH 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_048346 {REF} {Length: 14868} {TRANSSPLICED} {Pfam: Hydantoinase B/oxoprolinase [PF02538.16, score=677.6]; Hydantoinase/oxoprolinase [PF01968.20, score=348.4]; Hydantoinase/oxoprolinase N-terminal region [PF05378.15, score=172.3]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=128.4]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=113.3]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=76.9]; Integrase zinc binding domain [PF17921.3, score=68.9]; Aspartyl protease [PF13650.8, score=38.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=35.2]; Hydantoinase/oxoprolinase C-terminal domain [PF19278.1, score=25.9]; Retroviral aspartyl protease [PF00077.22, score=24.3]; Aspartyl protease [PF09668.12, score=23.4]; Putative peptidase (DUF1758) [PF05585.14, score=21.1]} {Human: ENSG00000178814, OPLAH, 5-oxoprolinase, ATP-hydrolysing, [Score=800, Expect=0.0]} {Mouse: ENSMUSG00000022562, Oplah, 5-oxoprolinase (ATP-hydrolysing), [Score=779, Expect=0.0]} {Dmel: FBgn0034733, CG4752, [Score=757, Expect=0.0]} {Celegans: WBGene00021430, Y38F2AR.12, [Score=763, Expect=0.0]} {Smed: dd_Smed_v6_5008_0_1, dd_Smed_v6_5008_0_1, [Score=847, Expect=0.0]} {RNA1509_20493} {RNA1310_131.1} {RNA815_52.1}
2. MligTC455_27832 1170 24.38 Mlig455_048328

Neo: Irradiation

Age: -

Region-enriched R5: 1.315/0.00946

 OPLAH 5.689 1.000 1.000 0.882 0.990 0.835 0.982 Mlig455_048328 {REF} {Length: 9221} {Pfam: Hydantoinase B/oxoprolinase [PF02538.16, score=675.2]; Hydantoinase/oxoprolinase [PF01968.20, score=305.4]; Hydantoinase/oxoprolinase N-terminal region [PF05378.15, score=151.6]; Hydantoinase/oxoprolinase C-terminal domain [PF19278.1, score=26.4]} {Human: ENSG00000178814, OPLAH, 5-oxoprolinase, ATP-hydrolysing, [Score=795, Expect=0.0]} {Mouse: ENSMUSG00000022562, Oplah, 5-oxoprolinase (ATP-hydrolysing), [Score=777, Expect=0.0]} {Dmel: FBgn0034733, CG4752, [Score=756, Expect=0.0]} {Celegans: WBGene00021430, Y38F2AR.12, [Score=762, Expect=0.0]} {Smed: dd_Smed_v6_5008_0_1, dd_Smed_v6_5008_0_1, [Score=845, Expect=0.0]} {RNA1509_2948} {RNA1310_4544} {RNA815_468}
3. MligTC455_27831 1160 24.16 Mlig455_048304

Neo: -

Age: -

Region-enriched R5: 1.322/0.01164

 OPLAH 5.675 0.998 1.000 0.882 0.988 0.834 0.973 Mlig455_048304 {REF} {Length: 1597} {Pfam: Hydantoinase B/oxoprolinase [PF02538.16, score=677.6]; Hydantoinase/oxoprolinase [PF01968.20, score=348.4]; Hydantoinase/oxoprolinase N-terminal region [PF05378.15, score=172.3]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=128.4]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=113.3]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=76.9]; Integrase zinc binding domain [PF17921.3, score=68.9]; Aspartyl protease [PF13650.8, score=38.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=35.2]; Hydantoinase/oxoprolinase C-terminal domain [PF19278.1, score=25.9]; Retroviral aspartyl protease [PF00077.22, score=24.3]; Aspartyl protease [PF09668.12, score=23.4]; Putative peptidase (DUF1758) [PF05585.14, score=21.1]} {Human: ENSG00000178814, OPLAH, 5-oxoprolinase, ATP-hydrolysing, [Score=800, Expect=0.0]} {Mouse: ENSMUSG00000022562, Oplah, 5-oxoprolinase (ATP-hydrolysing), [Score=779, Expect=0.0]} {Dmel: FBgn0034733, CG4752, [Score=757, Expect=0.0]} {Celegans: WBGene00021430, Y38F2AR.12, [Score=763, Expect=0.0]} {Smed: dd_Smed_v6_5008_0_1, dd_Smed_v6_5008_0_1, [Score=847, Expect=0.0]} {RNA1509_2948} {RNA1310_1508.2} {RNA815_468}
4. MligTC455_52038 1730 36.03 Mlig455_015106

Neo: -

Age: -

Region-enriched R3: 1.279/0.00028

 ACOX1 3.323 - 0.756 0.845 0.769 - 0.953 Mlig455_015106 {REF} {Length: 2669} {TRANSSPLICED} {Pfam: Acyl-CoA oxidase [PF01756.21, score=146.2]; Acyl-coenzyme A oxidase N-terminal [PF14749.8, score=121.0]; Acyl-CoA dehydrogenase, middle domain [PF02770.21, score=48.6]; Acyl-CoA dehydrogenase, C-terminal domain [PF00441.26, score=23.4]} {Human: ENSG00000161533, ACOX1, acyl-CoA oxidase 1, [RH, Score=600, Expect=0.0]} {Mouse: ENSMUSG00000020777, Acox1, acyl-Coenzyme A oxidase 1, palmitoyl, [RH, Score=605, Expect=0.0]} {Dmel: FBgn0027572, CG5009, [RH, Score=484, Expect=3e-163]} {Celegans: WBGene00010336, acox-1.6, Acyl-coenzyme A oxidase, [RH, Score=505, Expect=2e-171]} {Smed: dd_Smed_v6_3804_0_1, dd_Smed_v6_3804_0_1, [Score=253, Expect=1e-74]} {RNA1509_2548} {RNA1310_6629} {RNA815_1719.1}
5. MligTC455_45420 2046 42.62 Mlig455_056064, Mlig455_061586

Neo: -

Age: -

Region-enriched R3: 2.079/0.03891

 3.193 0.712 0.702 - 0.816 - 0.963

Mlig455_056064 {REF} {Length: 1343} {Pfam: Sleepless protein [PF17064.7, score=32.6]} {Celegans: WBGene00019663, K11H12.7, [RH, Score=58.5, Expect=1e-11]} {Smed: dd_Smed_v6_780_0_1, dd_Smed_v6_780_0_1, [Score=51.6, Expect=7e-09]} {RNA1509_9020} {RNA1310_25351.3} {RNA815_8070}

Mlig455_061586 {REF} {Length: 1849} {Pfam: Sleepless protein [PF17064.7, score=32.6]} {Celegans: WBGene00019663, K11H12.7, [RH, Score=58.5, Expect=1e-11]} {Smed: dd_Smed_v6_780_0_1, dd_Smed_v6_780_0_1, [Score=51.6, Expect=7e-09]} {RNA1509_48946, RNA1509_9020} {RNA1310_25351.3, RNA1509_48946, RNA1509_9020} {RNA1509_48946, RNA1509_9020, RNA815_8070}
6. MligTC455_40426 1948 40.58 Mlig455_060322

Neo: -

Age: -

 CERS1 2.564 0.780 - 0.825 0.959 - - Mlig455_060322 {REF} {Length: 3135} {TRANSSPLICED} {Pfam: TLC domain [PF03798.18, score=117.1]} {Human: ENSG00000223802, CERS1, ceramide synthase 1, [RH, Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000087408, Cers1, ceramide synthase 1, [RH, Score=218, Expect=1e-67]} {Dmel: FBgn0040918, schlank, [Score=79.7, Expect=5e-16]} {Celegans: WBGene00006505, lagr-1, Probable ceramide synthase lagr-1, [RH, Score=162, Expect=4e-46]} {Smed: dd_Smed_v6_3137_0_1, dd_Smed_v6_3137_0_1, [RH, Score=305, Expect=2e-101]} {RNA1509_13507, RNA1509_17195, RNA1509_43382, RNA1509_43716, RNA1509_47750, RNA1509_7808} {RNA1310_19552.1, RNA1509_13507, RNA1509_17195, RNA1509_43382, RNA1509_43716, RNA1509_47750, RNA1509_7808} {RNA1509_13507, RNA1509_17195, RNA1509_43382, RNA1509_43716, RNA1509_47750, RNA1509_7808, RNA815_8049.1}
7. MligTC455_27992 3646 75.95 Mlig455_023848

Neo: Neoblast

Age: -

Region-enriched R5: 1.362/0.00055
Region-enriched R4: 1.195/0.02469

 PPIA 2.526 0.711 - 0.963 0.852 - - Mlig455_023848 {REF} {Length: 1068} {TRANSSPLICED} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=252.2]} {Human: ENSG00000196262, PPIA, peptidylprolyl isomerase A, [Score=212, Expect=1e-68]; ENSG00000108179, PPIF, peptidylprolyl isomerase F, [Score=206, Expect=6e-66]} {Mouse: ENSMUSG00000021868, Ppif, peptidylprolyl isomerase F (cyclophilin F), [Score=212, Expect=3e-68]; ENSMUSG00000071866, Ppia, peptidylprolyl isomerase A, [Score=210, Expect=4e-68]} {Dmel: FBgn0036415, CG7768, [Score=205, Expect=2e-66]} {Celegans: WBGene00000883, cyn-7, Peptidyl-prolyl cis-trans isomerase 7, [Score=223, Expect=4e-73]} {Smed: dd_Smed_v6_457_0_1, dd_Smed_v6_457_0_1, [Score=212, Expect=4e-69]} {RNA1509_1425} {RNA1310_55233} {RNA815_27193}
8. MligTC455_53952 1529 31.86 Mlig455_034681

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.229

Region-enriched R4: 1.166/0.00320

 GLUD1 2.487 - - 0.717 0.820 - 0.950 Mlig455_034681 {REF} {Length: 2767} {TRANSSPLICED} {Pfam: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain [PF02812.20, score=194.2]; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=169.3]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [RH, Score=777, Expect=0.0]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [RH, Score=765, Expect=0.0]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [RH, Score=781, Expect=0.0]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [RH, Score=746, Expect=0.0]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [RH, Score=640, Expect=0.0]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [RH, Score=715, Expect=0.0]} {RNA1509_2392, RNA1509_31707, RNA1509_54464, RNA1509_55169, RNA1509_7066} {RNA1310_6874, RNA1509_2392, RNA1509_31707, RNA1509_54464, RNA1509_55169, RNA1509_7066} {RNA1509_2392, RNA1509_31707, RNA1509_54464, RNA1509_55169, RNA1509_7066, RNA815_2103.1}
9. MligTC455_44981 565 11.76 Mlig455_038443

Neo: Int S/G2/M

Age: -

Region-enriched R3: 1.137/0.04347

 LZIC 2.436 - - - 0.738 0.721 0.977 Mlig455_038443 {REF} {Length: 2241} {TRANSSPLICED} {Pfam: Beta-catenin-interacting protein ICAT [PF06384.13, score=67.0]; AefR-like transcriptional repressor, C-terminal domain [PF14246.8, score=18.8]} {Human: ENSG00000162441, LZIC, leucine zipper and CTNNBIP1 domain containing, [RH, Score=191, Expect=3e-61]} {Mouse: ENSMUSG00000028990, Lzic, leucine zipper and CTNNBIP1 domain containing, [RH, Score=190, Expect=2e-61]} {Celegans: WBGene00022885, ZK1248.19, [RH, Score=107, Expect=2e-29]} {RNA1509_8229} {RNA1310_42784} {RNA815_19558}
10. MligTC455_50420 1582 32.96 Mlig455_044844, Mlig455_044936

Neo: -

Age: logFC(26M/2M)=-0.481

 SLC5A12 2.414 - 0.729 0.722 - - 0.963

Mlig455_044844 {REF} {Length: 3138} {Pfam: Sodium:solute symporter family [PF00474.19, score=96.2]} {Human: ENSG00000148942, SLC5A12, solute carrier family 5 member 12, [Score=305, Expect=4e-95]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=298, Expect=3e-92]; ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=298, Expect=3e-92]; ENSG00000138074, SLC5A6, solute carrier family 5 member 6, [Score=294, Expect=1e-90]} {Mouse: ENSMUSG00000041644, Slc5a12, solute carrier family 5 (sodium/glucose cotransporter), member 12, [Score=300, Expect=2e-93]; ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=297, Expect=3e-92]; ENSMUSG00000006641, Slc5a6, solute carrier family 5 (sodium-dependent vitamin transporter), member 6, [Score=290, Expect=2e-89]} {Dmel: FBgn0034494, CG10444, [Score=280, Expect=5e-86]} {Celegans: WBGene00014092, ZK822.5, [Score=215, Expect=5e-62]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [Score=285, Expect=2e-88]} {RNA1509_18508} {RNA1310_13650.1} {RNA815_10147}

Mlig455_044936 {REF} {Length: 3192} {Pfam: Sodium:solute symporter family [PF00474.19, score=99.0]} {Human: ENSG00000148942, SLC5A12, solute carrier family 5 member 12, [Score=306, Expect=2e-95]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=299, Expect=1e-92]; ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=299, Expect=1e-92]; ENSG00000138074, SLC5A6, solute carrier family 5 member 6, [Score=298, Expect=6e-92]} {Mouse: ENSMUSG00000041644, Slc5a12, solute carrier family 5 (sodium/glucose cotransporter), member 12, [Score=301, Expect=8e-94]; ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=299, Expect=7e-93]; ENSMUSG00000006641, Slc5a6, solute carrier family 5 (sodium-dependent vitamin transporter), member 6, [Score=291, Expect=1e-89]} {Dmel: FBgn0034494, CG10444, [Score=281, Expect=2e-86]} {Celegans: WBGene00014092, ZK822.5, [Score=217, Expect=1e-62]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [Score=287, Expect=4e-89]} {RNA1509_18508, RNA1509_21413} {RNA1310_13650.1, RNA1509_18508, RNA1509_21413} {RNA1509_18508, RNA1509_21413, RNA815_10147}
11. MligTC455_32451 561 11.68 Mlig455_050691

Neo: -

Age: logFC(26M/2M)=0.579

Region-enriched R4: 2.742/0.00050
Region-enriched R3: 2.196/0.00081
Region-enriched R5: 1.487/0.02265

 ACHE 1.88 - - - 0.898 - 0.982 Mlig455_050691 {REF} {Length: 5112} {Pfam: Carboxylesterase family [PF00135.30, score=505.9]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=204, Expect=8e-55]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=183, Expect=3e-48]; ENSMUSG00000027792, Bche, butyrylcholinesterase, [Score=176, Expect=1e-45]; ENSMUSG00000058019, Ces5a, carboxylesterase 5A, [Score=174, Expect=2e-45]} {Dmel: FBgn0029690, CG6414, [RH, Score=172, Expect=1e-44]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=180, Expect=3e-47]} {Smed: dd_Smed_v6_4935_0_1, dd_Smed_v6_4935_0_1, [Score=176, Expect=2e-45]} {RNA1509_1740, RNA1509_22301} {RNA1310_963.1, RNA1509_1740, RNA1509_22301} {RNA1509_1740, RNA1509_22301, RNA815_836}
12. MligTC455_39815 586 12.2 Mlig455_022414

Neo: -

Age: -

 GRAMD2B 1.862 - - - 0.911 - 0.951 Mlig455_022414 {REF} {Length: 3008} {Pfam: GRAM domain [PF02893.22, score=57.7]} {Human: ENSG00000155324, GRAMD2B, GRAM domain containing 2B, [RH, Score=92.0, Expect=5e-20]} {Mouse: ENSMUSG00000001700, Gramd3, GRAM domain containing 3, [RH, Score=93.2, Expect=1e-20]} {Dmel: FBgn0085423, CG34394, [Score=90.1, Expect=2e-19]} {Celegans: WBGene00022593, ZC328.3, [Score=62.8, Expect=1e-10]} {Smed: dd_Smed_v6_8544_1_1, dd_Smed_v6_8544_1_1, [RH, Score=124, Expect=4e-32]} {RNA1509_31678} {RNA1310_9711.1} {RNA815_8169}
13. MligTC455_22795 949 19.76 Mlig455_024439

Neo: -

Age: -

 D2HGDH 1.848 - - - 0.874 - 0.974 Mlig455_024439 {REF} {Length: 2313} {TRANSSPLICED} {Pfam: FAD linked oxidases, C-terminal domain [PF02913.21, score=184.7]; FAD binding domain [PF01565.25, score=128.8]} {Human: ENSG00000180902, D2HGDH, D-2-hydroxyglutarate dehydrogenase, [RH, Score=559, Expect=0.0]} {Mouse: ENSMUSG00000073609, D2hgdh, D-2-hydroxyglutarate dehydrogenase, [RH, Score=561, Expect=0.0]} {Dmel: FBgn0023507, D2hgdh, D-2-hydroxyglutaric acid dehydrogenase, [RH, Score=503, Expect=1e-174]} {Celegans: WBGene00010055, F54D5.12, [RH, Score=423, Expect=3e-144]} {Smed: dd_Smed_v6_6440_0_1, dd_Smed_v6_6440_0_1, [RH, Score=533, Expect=0.0]} {RNA1509_57878, RNA1509_7824} {RNA1310_15861, RNA1509_57878, RNA1509_7824} {RNA1509_57878, RNA1509_7824, RNA815_6139}
14. MligTC455_44206 1609 33.53 Mlig455_023756, Mlig455_023769, Mlig455_023781

Neo: -

Age: -

 LACTB2 1.831 - - - 0.854 - 0.977

Mlig455_023756 {REF} {Length: 1648} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=72.8]; Beta-lactamase associated winged helix domain [PF17778.3, score=25.6]; ODP family beta lactamase [PF19583.1, score=23.7]} {Human: ENSG00000147592, LACTB2, lactamase beta 2, [RH, Score=185, Expect=1e-56]} {Mouse: ENSMUSG00000025937, Lactb2, lactamase, beta 2, [RH, Score=181, Expect=3e-55]} {Dmel: FBgn0031987, CG12375, [RH, Score=173, Expect=2e-52]} {Celegans: WBGene00013176, Y53F4B.39, Beta-lactamase-like protein 2 homolog, [RH, Score=184, Expect=2e-56]} {Smed: dd_Smed_v6_7055_0_1, dd_Smed_v6_7055_0_1, [RH, Score=192, Expect=2e-59]} {RNA1509_19026} {RNA1310_16885} {RNA815_2513}

Mlig455_023769 {REF} {Length: 1651} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=72.8]; Beta-lactamase associated winged helix domain [PF17778.3, score=25.6]; ODP family beta lactamase [PF19583.1, score=23.7]} {Human: ENSG00000147592, LACTB2, lactamase beta 2, [RH, Score=185, Expect=1e-56]} {Mouse: ENSMUSG00000025937, Lactb2, lactamase, beta 2, [RH, Score=181, Expect=3e-55]} {Dmel: FBgn0031987, CG12375, [RH, Score=173, Expect=2e-52]} {Celegans: WBGene00013176, Y53F4B.39, Beta-lactamase-like protein 2 homolog, [RH, Score=184, Expect=2e-56]} {Smed: dd_Smed_v6_7055_0_1, dd_Smed_v6_7055_0_1, [RH, Score=192, Expect=2e-59]} {RNA1509_19026} {RNA1310_16885} {RNA815_2513}

Mlig455_023781 {REF} {Length: 1649} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=72.8]; Beta-lactamase associated winged helix domain [PF17778.3, score=25.6]; ODP family beta lactamase [PF19583.1, score=23.7]} {Human: ENSG00000147592, LACTB2, lactamase beta 2, [RH, Score=185, Expect=1e-56]} {Mouse: ENSMUSG00000025937, Lactb2, lactamase, beta 2, [RH, Score=181, Expect=3e-55]} {Dmel: FBgn0031987, CG12375, [RH, Score=173, Expect=2e-52]} {Celegans: WBGene00013176, Y53F4B.39, Beta-lactamase-like protein 2 homolog, [RH, Score=184, Expect=2e-56]} {Smed: dd_Smed_v6_7055_0_1, dd_Smed_v6_7055_0_1, [RH, Score=192, Expect=2e-59]} {RNA1509_19026} {RNA1310_16885, RNA1509_19026} {RNA1509_19026, RNA815_2513}
15. MligTC455_16824 1812 37.75 Mlig455_003697, Mlig455_003738, Mlig455_003903

Neo: -

Age: Up-Down-Down

 SMPD1 1.83 - - - 0.876 - 0.954

Mlig455_003697 {REF} {Length: 1645} {Pfam: Acid sphingomyelin phosphodiesterase C-terminal region [PF19272.1, score=20.8]; PAN domain [PF00024.28, score=18.8]} {Human: ENSG00000166311, SMPD1, sphingomyelin phosphodiesterase 1, [Score=73.6, Expect=4e-13]} {Mouse: ENSMUSG00000037049, Smpd1, sphingomyelin phosphodiesterase 1, acid lysosomal, [Score=68.2, Expect=1e-11]} {Dmel: FBgn0034997, CG3376, [Score=55.8, Expect=7e-08]} {Celegans: WBGene00000213, asm-3, Putative sphingomyelin phosphodiesterase asm-3, [Score=53.5, Expect=3e-07]} {Smed: dd_Smed_v6_38541_0_1, dd_Smed_v6_38541_0_1, [Score=65.9, Expect=5e-12]} {RNA1509_5998} {RNA1310_33480} {RNA815_17816.1}

Mlig455_003738 {REF} {Length: 2484} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=90.8]; Acid sphingomyelin phosphodiesterase C-terminal region [PF19272.1, score=40.9]} {Human: ENSG00000166311, SMPD1, sphingomyelin phosphodiesterase 1, [RH, Score=376, Expect=1e-122]} {Mouse: ENSMUSG00000037049, Smpd1, sphingomyelin phosphodiesterase 1, acid lysosomal, [RH, Score=374, Expect=6e-122]} {Dmel: FBgn0034997, CG3376, [Score=361, Expect=2e-116]} {Celegans: WBGene00000213, asm-3, Putative sphingomyelin phosphodiesterase asm-3, [RH, Score=340, Expect=8e-110]} {Smed: dd_Smed_v6_15691_0_1, dd_Smed_v6_15691_0_1, [Score=71.2, Expect=6e-13]} {RNA1509_5998} {RNA1310_9448} {RNA815_4533}

Mlig455_003903 {REF} {Length: 2345} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=89.9]; Acid sphingomyelin phosphodiesterase C-terminal region [PF19272.1, score=40.5]} {Human: ENSG00000166311, SMPD1, sphingomyelin phosphodiesterase 1, [RH, Score=379, Expect=5e-124]} {Mouse: ENSMUSG00000037049, Smpd1, sphingomyelin phosphodiesterase 1, acid lysosomal, [RH, Score=377, Expect=4e-123]} {Dmel: FBgn0034997, CG3376, [RH, Score=367, Expect=9e-118]} {Celegans: WBGene00000213, asm-3, Putative sphingomyelin phosphodiesterase asm-3, [RH, Score=338, Expect=5e-109]} {Smed: dd_Smed_v6_15691_0_1, dd_Smed_v6_15691_0_1, [Score=65.1, Expect=5e-11]} {RNA1509_5998} {RNA1310_9448, RNA1509_5998} {RNA1509_5998, RNA815_4533}
16. MligTC455_40127 1207 25.14 Mlig455_017076

Neo: -

Age: -

Region-enriched R4: 1.077/0.01220

 GRAMD1B 1.812 - - - 0.843 - 0.969 Mlig455_017076 {REF} {Length: 1982} {TRANSSPLICED} {Pfam: VAD1 Analog of StAR-related lipid transfer domain [PF16016.7, score=85.8]} {Human: ENSG00000023171, GRAMD1B, GRAM domain containing 1B, [RH, Score=78.2, Expect=6e-15]} {Mouse: ENSMUSG00000040111, Gramd1b, GRAM domain containing 1B, [RH, Score=80.9, Expect=7e-16]} {Dmel: FBgn0085423, CG34394, [RH, Score=69.3, Expect=3e-12]} {Smed: dd_Smed_v6_9149_0_1, dd_Smed_v6_9149_0_1, [Score=73.9, Expect=6e-14]} {RNA1509_11472} {RNA1310_17969, RNA1509_11472} {RNA1509_11472, RNA815_18157}
17. MligTC455_39776 1144 23.84 Mlig455_053212, Mlig455_065058

Neo: Neoblast, stringent

Age: -

Region-specific R5: 2.245

Region-enriched R5: 1.733/0.00000
Region-enriched R4: 1.649/0.00127

 PLK1 1.805 0.840 - - 0.965 - -

Mlig455_053212 {REF} {Length: 3361} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=226.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=146.5]; POLO box duplicated region [PF00659.20, score=127.0]; Kinase-like [PF14531.8, score=33.4]; Fungal protein kinase [PF17667.3, score=30.6]} {Human: ENSG00000166851, PLK1, polo like kinase 1, [RH, Score=594, Expect=0.0]} {Mouse: ENSMUSG00000030867, Plk1, polo like kinase 1, [RH, Score=614, Expect=0.0]} {Dmel: FBgn0003124, polo, [RH, Score=530, Expect=0.0]} {Celegans: WBGene00004043, plk-2, Serine/threonine-protein kinase plk-2, [RH, Score=561, Expect=0.0]} {Smed: dd_Smed_v6_4273_0_1, dd_Smed_v6_4273_0_1, [RH, Score=500, Expect=2e-171]} {RNA1509_5301} {RNA1310_3713} {RNA815_3603}

Mlig455_065058 {REF} {Length: 3509} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=226.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=146.5]; POLO box duplicated region [PF00659.20, score=126.5]; Kinase-like [PF14531.8, score=33.4]; Fungal protein kinase [PF17667.3, score=30.6]} {Human: ENSG00000166851, PLK1, polo like kinase 1, [RH, Score=593, Expect=0.0]} {Mouse: ENSMUSG00000030867, Plk1, polo like kinase 1, [RH, Score=612, Expect=0.0]} {Dmel: FBgn0003124, polo, [RH, Score=530, Expect=0.0]} {Celegans: WBGene00004043, plk-2, Serine/threonine-protein kinase plk-2, [RH, Score=561, Expect=0.0]} {Smed: dd_Smed_v6_4273_0_1, dd_Smed_v6_4273_0_1, [RH, Score=499, Expect=3e-171]} {RNA1509_38334, RNA1509_44423, RNA1509_49051, RNA1509_5301} {RNA1310_3713, RNA1509_38334, RNA1509_44423, RNA1509_49051, RNA1509_5301} {RNA1509_38334, RNA1509_44423, RNA1509_49051, RNA1509_5301, RNA815_3603}
18. MligTC455_39775 565 11.77 Mlig455_051815

Neo: Irradiation

Age: Up-Up-Down

Region-enriched R5: 1.729/0.00000
Region-enriched R4: 1.615/0.00542

 PLK1 1.802 0.837 - - 0.965 - - Mlig455_051815 {REF} {Length: 2862} {Pfam: POLO box duplicated region [PF00659.20, score=67.1]; Protein kinase domain [PF00069.27, score=55.6]} {Human: ENSG00000166851, PLK1, polo like kinase 1, [Score=261, Expect=2e-80]} {Mouse: ENSMUSG00000030867, Plk1, polo like kinase 1, [Score=265, Expect=4e-82]} {Dmel: FBgn0003124, polo, [Score=192, Expect=6e-55]} {Celegans: WBGene00004043, plk-2, Serine/threonine-protein kinase plk-2, [Score=216, Expect=1e-63]} {Smed: dd_Smed_v6_4273_0_1, dd_Smed_v6_4273_0_1, [Score=198, Expect=2e-57]} {RNA1509_49051} {RNA1310_4665} {RNA815_3603}
19. MligTC455_36089 867 18.05 Mlig455_035111, Mlig455_062422

Neo: -

Age: -

 ACSS1 1.799 - - - 0.841 - 0.958

Mlig455_035111 {REF} {Length: 2972} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=271.7]; AMP-binding enzyme C-terminal domain [PF13193.8, score=89.2]; Acetyl-coenzyme A synthetase N-terminus [PF16177.7, score=39.6]} {Human: ENSG00000154930, ACSS1, acyl-CoA synthetase short chain family member 1, [RH, Score=733, Expect=0.0]} {Mouse: ENSMUSG00000027452, Acss1, acyl-CoA synthetase short-chain family member 1, [RH, Score=748, Expect=0.0]} {Dmel: FBgn0012034, AcCoAS, Acetyl Coenzyme A synthase, [Score=526, Expect=2e-179]} {Celegans: WBGene00007969, acs-19, Acetyl-coenzyme A synthetase, [Score=491, Expect=5e-166]} {Smed: dd_Smed_v6_6561_0_1, dd_Smed_v6_6561_0_1, [RH, Score=717, Expect=0.0]} {RNA1509_44916} {RNA1310_11929} {RNA815_3848}

Mlig455_062422 {REF} {Length: 2961} {TRANSSPLICED} {Pfam: AMP-binding enzyme [PF00501.30, score=287.6]; AMP-binding enzyme C-terminal domain [PF13193.8, score=89.2]; Acetyl-coenzyme A synthetase N-terminus [PF16177.7, score=40.0]} {Human: ENSG00000154930, ACSS1, acyl-CoA synthetase short chain family member 1, [RH, Score=742, Expect=0.0]} {Mouse: ENSMUSG00000027452, Acss1, acyl-CoA synthetase short-chain family member 1, [RH, Score=757, Expect=0.0]} {Dmel: FBgn0012034, AcCoAS, Acetyl Coenzyme A synthase, [Score=533, Expect=0.0]} {Celegans: WBGene00007969, acs-19, Acetyl-coenzyme A synthetase, [Score=500, Expect=2e-169]} {Smed: dd_Smed_v6_6561_0_1, dd_Smed_v6_6561_0_1, [RH, Score=720, Expect=0.0]} {RNA1509_44916} {RNA1310_11929} {RNA815_3848}
20. MligTC455_44283 328 6.84 Mlig455_009513, Mlig455_070902

Neo: -

Age: -

Region-enriched R4: 2.039/0.03671
Region-enriched R5: 1.678/0.01886

 RAB1A 1.775 - - 0.821 0.954 - -

Mlig455_009513 {REF} {Length: 872} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=222.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=128.2]; ADP-ribosylation factor family [PF00025.23, score=64.5]; RsgA GTPase [PF03193.18, score=28.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=26.9]; 50S ribosome-binding GTPase [PF01926.25, score=25.4]; Gtr1/RagA G protein conserved region [PF04670.14, score=24.6]; Signal recognition particle receptor beta subunit [PF09439.12, score=24.1]} {Human: ENSG00000138069, RAB1A, RAB1A, member RAS oncogene family, [RH, Score=356, Expect=1e-126]; ENSG00000174903, RAB1B, RAB1B, member RAS oncogene family, [RH, Score=347, Expect=5e-123]} {Mouse: ENSMUSG00000020149, Rab1a, RAB1A, member RAS oncogene family, [RH, Score=356, Expect=1e-126]; ENSMUSG00000024870, Rab1b, RAB1B, member RAS oncogene family, [RH, Score=348, Expect=1e-123]} {Dmel: FBgn0285937, Rab1, [RH, Score=341, Expect=6e-121]} {Celegans: WBGene00004266, rab-1, RAB family, [RH, Score=341, Expect=7e-121]} {Smed: dd_Smed_v6_488_0_1, dd_Smed_v6_488_0_1, [RH, Score=346, Expect=5e-123]} {RNA1509_45775} {RNA1310_31708} {RNA815_16312}

Mlig455_070902 {REF} {Length: 1104} {Pfam: Ras family [PF00071.24, score=222.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=128.2]; ADP-ribosylation factor family [PF00025.23, score=64.5]; RsgA GTPase [PF03193.18, score=28.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=26.9]; 50S ribosome-binding GTPase [PF01926.25, score=25.4]; Gtr1/RagA G protein conserved region [PF04670.14, score=24.6]; Signal recognition particle receptor beta subunit [PF09439.12, score=24.1]} {Human: ENSG00000138069, RAB1A, RAB1A, member RAS oncogene family, [RH, Score=356, Expect=1e-126]; ENSG00000174903, RAB1B, RAB1B, member RAS oncogene family, [RH, Score=347, Expect=5e-123]} {Mouse: ENSMUSG00000020149, Rab1a, RAB1A, member RAS oncogene family, [RH, Score=356, Expect=1e-126]; ENSMUSG00000024870, Rab1b, RAB1B, member RAS oncogene family, [RH, Score=348, Expect=1e-123]} {Dmel: FBgn0285937, Rab1, [RH, Score=341, Expect=6e-121]} {Celegans: WBGene00004266, rab-1, RAB family, [RH, Score=341, Expect=7e-121]} {Smed: dd_Smed_v6_488_0_1, dd_Smed_v6_488_0_1, [RH, Score=346, Expect=5e-123]} {RNA1509_26321, RNA1509_3794, RNA1509_41625, RNA1509_45775, RNA1509_48881} {RNA1310_31708, RNA1509_26321, RNA1509_3794, RNA1509_41625, RNA1509_45775, RNA1509_48881} {RNA1509_26321, RNA1509_3794, RNA1509_41625, RNA1509_45775, RNA1509_48881, RNA815_16312}
21. MligTC455_29086 937 19.52 Mlig455_050487

Neo: Int S/G2/M

Age: Down-Up-Up

Region-enriched R4: 1.822/0.00015
Region-enriched R5: 1.143/0.00402

 POLR2J 1.745 - - 0.788 0.957 - - Mlig455_050487 {REF} {Length: 612} {TRANSSPLICED} {Pfam: RNA polymerase Rpb3/Rpb11 dimerisation domain [PF13656.8, score=89.2]; RNA polymerase Rpb3/Rpb11 dimerisation domain [PF01193.26, score=34.5]} {Human: ENSG00000005075, POLR2J, RNA polymerase II subunit J, [RH, Score=160, Expect=4e-52]; ENSG00000168255, POLR2J3, RNA polymerase II subunit J3, [RH, Score=154, Expect=9e-50]; ENSG00000285437, POLR2J3, RNA polymerase II subunit J3, [RH, Score=154, Expect=9e-50]; ENSG00000228049, POLR2J2, RNA polymerase II subunit J2, [RH, Score=152, Expect=7e-49]; ENSG00000267645, AC105052.3, novel protein, POLR2J2-UPK3BL readthrough, [RH, Score=152, Expect=7e-49]} {Mouse: ENSMUSG00000039771, Polr2j, polymerase (RNA) II (DNA directed) polypeptide J, [RH, Score=160, Expect=3e-52]} {Dmel: FBgn0032634, Rpb11, [RH, Score=147, Expect=3e-47]} {Celegans: WBGene00012187, rpb-11, Probable DNA-directed RNA polymerase II subunit RPB11, [RH, Score=127, Expect=3e-39]} {Smed: dd_Smed_v6_4232_0_1, dd_Smed_v6_4232_0_1, [RH, Score=129, Expect=2e-40]} {RNA1509_11952} {RNA1310_52973, RNA1509_11952} {RNA1509_11952, RNA815_30007}
22. MligTC455_49231 1726 35.96 Mlig455_058129

Neo: Neoblast

Age: Down-Down-Up, logFC(26M/2M)=0.199

Region-enriched R5: 1.040/0.00189

 PHB 1.734 0.766 - - 0.968 - - Mlig455_058129 {REF} {Length: 1924} {TRANSSPLICED} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=86.2]} {Human: ENSG00000167085, PHB, prohibitin, [RH, Score=370, Expect=8e-130]} {Mouse: ENSMUSG00000038845, Phb, prohibitin, [RH, Score=369, Expect=1e-129]} {Dmel: FBgn0002031, l(2)37Cc, lethal (2) 37Cc, [RH, Score=373, Expect=3e-131]} {Celegans: WBGene00004014, phb-1, Mitochondrial prohibitin complex protein 1, [RH, Score=345, Expect=2e-120]} {Smed: dd_Smed_v6_1038_0_1, dd_Smed_v6_1038_0_1, [RH, Score=337, Expect=3e-117]} {RNA1509_3657} {RNA1310_32949.2} {RNA815_14267.1}
23. MligTC455_39669 2126 44.28 Mlig455_066231

Neo: -

Age: -

 MAP1A 1.729 - - - 0.774 - 0.955 Mlig455_066231 {REF} {Length: 5111} {Human: ENSG00000166963, MAP1A, microtubule associated protein 1A, [RH, Score=193, Expect=1e-49]; ENSG00000131711, MAP1B, microtubule associated protein 1B, [RH, Score=188, Expect=3e-48]} {Mouse: ENSMUSG00000027254, Map1a, microtubule-associated protein 1 A, [RH, Score=197, Expect=3e-51]; ENSMUSG00000052727, Map1b, microtubule-associated protein 1B, [RH, Score=189, Expect=1e-48]} {Dmel: FBgn0259108, futsch, [RH, Score=193, Expect=4e-50]} {Smed: dd_Smed_v6_2033_0_1, dd_Smed_v6_2033_0_1, [Score=67.8, Expect=2e-11]} {RNA1509_1113} {RNA1310_2536} {RNA815_684}
24. MligTC455_16803 1395 29.07 Mlig455_014928

Neo: -

Age: Down-Down-Up

 CIAPIN1 1.721 - - - 0.950 - 0.771 Mlig455_014928 {REF} {Length: 1519} {TRANSSPLICED} {Pfam: Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis [PF05093.15, score=81.0]} {Human: ENSG00000005194, CIAPIN1, cytokine induced apoptosis inhibitor 1, [Score=146, Expect=1e-41]} {Mouse: ENSMUSG00000031781, Ciapin1, cytokine induced apoptosis inhibitor 1, [Score=143, Expect=1e-40]} {Dmel: FBgn0001977, CIAPIN1, Cytokine induced apoptosis inhibitor 1, [Score=125, Expect=1e-34]} {Celegans: WBGene00020604, T20B12.7, Anamorsin homolog, [Score=112, Expect=7e-30]} {Smed: dd_Smed_v6_3204_0_1, dd_Smed_v6_3204_0_1, [Score=112, Expect=8e-30]} {RNA1509_16514, RNA1509_26139, RNA1509_38268, RNA1509_9335} {RNA1310_27669, RNA1509_16514, RNA1509_26139, RNA1509_38268, RNA1509_9335} {RNA1509_16514, RNA1509_26139, RNA1509_38268, RNA1509_9335, RNA815_11583.1}
25. MligTC455_45293 1305 27.18 Mlig455_051600

Neo: -

Age: -

 SUSD2 1.712 - - 0.762 - - 0.950 Mlig455_051600 {REF} {Length: 5138} {Pfam: von Willebrand factor type D domain [PF00094.27, score=37.0]} {Human: ENSG00000099994, SUSD2, sushi domain containing 2, [Score=82.8, Expect=6e-16]} {Mouse: ENSMUSG00000006342, Susd2, sushi domain containing 2, [Score=100, Expect=7e-22]} {Dmel: FBgn0051004, mesh, [Score=102, Expect=3e-22]} {RNA1509_1220, RNA1509_1883, RNA1509_34687, RNA1509_36798, RNA1509_40605} {RNA1310_2718.1, RNA1509_1883, RNA1509_34687, RNA1509_36798, RNA1509_40605} {RNA1509_1883, RNA1509_34687, RNA1509_36798, RNA1509_40605, RNA815_500}
26. MligTC455_39007 2184 45.51 Mlig455_062119, Mlig455_069663

Neo: Neoblast, stringent

Age: -

Region-enriched R5: 1.418/0.00014

Regeneration-upregulated BL: 1.963

Regeneration-enriched BL: 1.963

 NUP210, NUP210L 1.693 0.722 - - 0.971 - -

Mlig455_062119 {REF} {Length: 7147} {Pfam: Bacterial Ig-like domain (group 2) [PF02368.20, score=26.5]} {Human: ENSG00000132182, NUP210, nucleoporin 210, [RH, Score=536, Expect=2e-159]} {Mouse: ENSMUSG00000027939, Nup210l, nucleoporin 210-like, [RH, Score=506, Expect=2e-149]} {Dmel: FBgn0266580, Gp210, Glycoprotein 210 kDa, [RH, Score=243, Expect=2e-64]} {Celegans: WBGene00003798, npp-12, Nuclear Pore complex Protein, [Score=248, Expect=5e-66]} {Smed: dd_Smed_v6_4698_0_1, dd_Smed_v6_4698_0_1, [RH, Score=549, Expect=1e-163]} {RNA1509_2772} {RNA1310_410.1} {RNA815_6899}

Mlig455_069663 {REF} {Length: 6507} {Pfam: Bacterial Ig-like domain (group 2) [PF02368.20, score=22.5]} {Human: ENSG00000143552, NUP210L, nucleoporin 210 like, [Score=473, Expect=8e-137]} {Mouse: ENSMUSG00000027939, Nup210l, nucleoporin 210-like, [RH, Score=506, Expect=5e-148]} {Dmel: FBgn0266580, Gp210, Glycoprotein 210 kDa, [Score=224, Expect=2e-58]} {Celegans: WBGene00003798, npp-12, Nuclear Pore complex Protein, [RH, Score=226, Expect=6e-59]} {Smed: dd_Smed_v6_4698_0_1, dd_Smed_v6_4698_0_1, [Score=538, Expect=2e-158]} {RNA1509_2772} {RNA1310_410.1} {RNA815_6899}
27. MligTC455_47349 1450 30.22 Mlig455_010530, Mlig455_061804

Neo: Neoblast, stringent

Age: -

Region-enriched R5: 1.675/0.00004
Region-enriched R4: 1.345/0.03938

 DNMT3B 1.683 - - 0.723 0.960 - -

Mlig455_010530 {REF} {Length: 2248} {TRANSSPLICED} {Pfam: Cysteine rich ADD domain in DNMT3 [PF17980.3, score=29.7]} {Human: ENSG00000088305, DNMT3B, DNA methyltransferase 3 beta, [Score=89.0, Expect=1e-17]} {Mouse: ENSMUSG00000027478, Dnmt3b, DNA methyltransferase 3B, [Score=97.1, Expect=2e-20]; ENSMUSG00000082079, Dnmt3c, DNA methyltransferase 3C, [Score=94.7, Expect=1e-19]} {RNA1509_23149} {RNA1310_10697.1, RNA1509_23149} {RNA1509_23149, RNA815_14886}

Mlig455_061804 {REF} {Length: 2249} {TRANSSPLICED} {Pfam: Cysteine rich ADD domain in DNMT3 [PF17980.3, score=29.7]} {Human: ENSG00000088305, DNMT3B, DNA methyltransferase 3 beta, [Score=89.4, Expect=9e-18]} {Mouse: ENSMUSG00000027478, Dnmt3b, DNA methyltransferase 3B, [Score=97.1, Expect=2e-20]; ENSMUSG00000082079, Dnmt3c, DNA methyltransferase 3C, [Score=94.7, Expect=9e-20]} {RNA1509_23149} {RNA1310_10697.1} {RNA815_14886}
28. MligTC455_21609 576 12 Mlig455_019995

Neo: -

Age: logFC(26M/2M)=-0.355

Region-enriched R5: 1.448/0.04285

 PPEF1 1.66 - - - 0.950 0.710 - Mlig455_019995 {REF} {Length: 2672} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=91.9]; EF-hand domain pair [PF13499.8, score=82.4]; EF hand [PF00036.34, score=69.9]; EF-hand domain pair [PF13833.8, score=61.5]; EF-hand domain [PF13405.8, score=50.4]; PPP5 TPR repeat region [PF08321.14, score=37.8]; EF hand [PF13202.8, score=34.3]; EF-hand domain [PF14658.8, score=21.5]; IQ calmodulin-binding motif [PF00612.29, score=19.3]} {Human: ENSG00000086717, PPEF1, protein phosphatase with EF-hand domain 1, [RH, Score=555, Expect=0.0]} {Mouse: ENSMUSG00000062168, Ppef1, protein phosphatase with EF hand calcium-binding domain 1, [RH, Score=541, Expect=0.0]} {Dmel: FBgn0265959, rdgC, retinal degeneration C, [RH, Score=553, Expect=0.0]} {Celegans: WBGene00003969, pef-1, Serine/threonine-protein phosphatase with EF-hands pef-1, [RH, Score=625, Expect=0.0]} {Smed: dd_Smed_v6_11874_0_1, dd_Smed_v6_11874_0_1, [RH, Score=719, Expect=0.0]} {RNA1509_5920} {RNA1310_6882.1, RNA1509_5920} {RNA1509_5920, RNA815_2260.1}
29. MligTC455_30683 400 8.34 Mlig455_061059

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.757

Region-enriched R3: 2.039/0.00020
Region-enriched R4: 1.355/0.04754

Regeneration-upregulated R6: 2.095

Regeneration-enriched R6: 2.095

 0.97 - - - 0.970 - - Mlig455_061059 {REF} {Length: 3418} {Pfam: Fibronectin type III domain [PF00041.23, score=66.8]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=20.0]} {RNA1509_43854} {RNA1310_20229.1} {RNA815_718.1}
30. MligTC455_39433 348 7.25 Mlig455_067841

Neo: -

Age: Down-Up-Up

Region-enriched R4: 3.187/0.00988
Region-enriched R5: 3.060/0.00036

 EXOSC8 0.965 - - - 0.965 - - Mlig455_067841 {REF} {Length: 1741} {TRANSSPLICED} {Pfam: 3' exoribonuclease family, domain 1 [PF01138.23, score=65.0]} {Human: ENSG00000120699, EXOSC8, exosome component 8, [RH, Score=99.4, Expect=9e-24]} {Mouse: ENSMUSG00000027752, Exosc8, exosome component 8, [RH, Score=94.4, Expect=4e-22]} {RNA1509_38958} {RNA1310_20971, RNA1509_38958} {RNA1509_38958, RNA815_18350}
31. MligTC455_50839 771 16.06 Mlig455_019477, Mlig455_066887

Neo: Neoblast

Age: -

 POLR1D 0.964 - - - 0.964 - -

Mlig455_019477 {REF} {Length: 953} {TRANSSPLICED} {Pfam: RNA polymerase Rpb3/Rpb11 dimerisation domain [PF13656.8, score=78.0]; RNA polymerase Rpb3/Rpb11 dimerisation domain [PF01193.26, score=36.9]} {Human: ENSG00000186184, POLR1D, RNA polymerase I and III subunit D, [RH, Score=72.4, Expect=3e-16]} {Mouse: ENSMUSG00000029642, Polr1d, polymerase (RNA) I polypeptide D, [RH, Score=73.2, Expect=7e-17]} {Dmel: FBgn0086447, l(2)37Cg, lethal (2) 37Cg, [RH, Score=67.0, Expect=9e-15]} {Celegans: WBGene00012187, rpb-11, Probable DNA-directed RNA polymerase II subunit RPB11, [Score=70.5, Expect=3e-16]} {Smed: dd_Smed_v6_4232_0_1, dd_Smed_v6_4232_0_1, [Score=60.1, Expect=2e-12]} {RNA1509_36825} {RNA1310_36027} {RNA815_16873}

Mlig455_066887 {REF} {Length: 953} {TRANSSPLICED} {Pfam: RNA polymerase Rpb3/Rpb11 dimerisation domain [PF13656.8, score=78.0]; RNA polymerase Rpb3/Rpb11 dimerisation domain [PF01193.26, score=36.9]} {Human: ENSG00000186184, POLR1D, RNA polymerase I and III subunit D, [RH, Score=72.4, Expect=3e-16]} {Mouse: ENSMUSG00000029642, Polr1d, polymerase (RNA) I polypeptide D, [RH, Score=73.2, Expect=7e-17]} {Dmel: FBgn0086447, l(2)37Cg, lethal (2) 37Cg, [RH, Score=67.0, Expect=9e-15]} {Celegans: WBGene00012187, rpb-11, Probable DNA-directed RNA polymerase II subunit RPB11, [Score=70.5, Expect=3e-16]} {Smed: dd_Smed_v6_4232_0_1, dd_Smed_v6_4232_0_1, [Score=60.1, Expect=2e-12]} {RNA1509_25323, RNA1509_36825} {RNA1310_36027, RNA1509_25323, RNA1509_36825} {RNA1509_25323, RNA1509_36825, RNA815_16873}
32. MligTC455_24177 1390 28.95 Mlig455_034202

Neo: -

Age: logFC(26M/2M)=0.443

Region-enriched R5: 1.223/0.01600

 PC 0.96 - - - - - 0.960 Mlig455_034202 {REF} {Length: 4942} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=260.2]; Conserved carboxylase domain [PF02436.20, score=226.3]; Biotin carboxylase, N-terminal domain [PF00289.24, score=143.0]; Biotin carboxylase C-terminal domain [PF02785.21, score=107.6]; HMGL-like [PF00682.21, score=90.0]; Biotin-requiring enzyme [PF00364.24, score=55.9]; D-ala D-ala ligase C-terminus [PF07478.15, score=30.6]; Biotin-lipoyl like [PF13533.8, score=23.7]; ATP-grasp domain [PF02222.24, score=23.4]; Na(+)-translocating NADH-quinone reductase subunit A (NQRA) [PF05896.13, score=21.3]; HlyD family secretion protein [PF13437.8, score=20.8]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [RH, Score=1476, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [RH, Score=1466, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [RH, Score=1524, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [RH, Score=1470, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [RH, Score=1536, Expect=0.0]} {RNA1509_30437, RNA1509_35913, RNA1509_57702, RNA1509_886} {RNA1310_1164.1, RNA1509_30437, RNA1509_35913, RNA1509_57702, RNA1509_886} {RNA1509_30437, RNA1509_35913, RNA1509_57702, RNA1509_886, RNA815_728}
33. MligTC455_44586 1241 25.84 Mlig455_013329

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.029/0.00034

 ILF2 0.955 - - - 0.955 - - Mlig455_013329 {REF} {Length: 2132} {Pfam: DZF domain [PF07528.16, score=282.5]} {Human: ENSG00000143621, ILF2, interleukin enhancer binding factor 2, [RH, Score=400, Expect=1e-137]} {Mouse: ENSMUSG00000001016, Ilf2, interleukin enhancer binding factor 2, [RH, Score=400, Expect=8e-138]} {Dmel: FBgn0038046, CG5641, [RH, Score=387, Expect=2e-132]} {Celegans: WBGene00011253, R11H6.5, [RH, Score=155, Expect=4e-43]} {Smed: dd_Smed_v6_3548_0_1, dd_Smed_v6_3548_0_1, [RH, Score=401, Expect=4e-138]} {RNA1509_14247, RNA1509_57323} {RNA1310_13620.1, RNA1509_14247, RNA1509_57323} {RNA1509_14247, RNA1509_57323, RNA815_6092}
34. MligTC455_50965 454 9.45 Mlig455_029740

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.564

Region-enriched R5: 2.031/0.00400
Region-enriched R4: 1.965/0.04603

 NOL12 0.954 - - - 0.954 - - Mlig455_029740 {REF} {Length: 703} {TRANSSPLICED} {Pfam: Nucleolar protein 12 (25kDa) [PF09805.11, score=49.7]} {Human: ENSG00000273899, NOL12, nucleolar protein 12, [RH, Score=62.4, Expect=6e-12]; ENSG00000100101, Z83844.1, novel transcript, [RH, Score=61.6, Expect=9e-12]} {Mouse: ENSMUSG00000033099, Nol12, nucleolar protein 12, [RH, Score=59.7, Expect=4e-11]} {RNA1509_49191} {RNA1310_51251, RNA1509_49191} {RNA1509_49191, RNA815_24269}
35. MligTC455_42243 1197 24.93 Mlig455_002520

Neo: Neoblast, stringent

Age: logFC(26M/2M)=0.357

Region-specific R5: 3.136

Region-enriched R5: 2.806/0.00000
Region-enriched R6: 1.322/0.04695

 0.952 - - - 0.952 - - Mlig455_002520 {REF} {Length: 1175} {TRANSSPLICED} {RNA1509_56655} {RNA1310_26126, RNA1509_56655} {RNA1509_56655, RNA815_12984}
36. MligTC455_12517 587 12.23 Mlig455_023517

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-1.412

 0.95 - - - - - 0.950 Mlig455_023517 {REF} {Length: 661} {RNA1509_22223} {RNA1310_60769} {RNA815_31256}
37. MligTC455_20667 992 20.67 Mlig455_031254, Mlig455_031299, Mlig455_031329

Neo: Neoblast, stringent

Age: logFC(26M/2M)=0.264

Region-enriched R5: 1.345/0.00244

 XPC 0.95 - - - 0.950 - -

Mlig455_031254 {REF} {Length: 234} {NoTransDecoderORF} {RNA1509_41875} {RNA1310_5347}

Mlig455_031299 {REF} {Length: 5228} {Pfam: Rad4 beta-hairpin domain 3 [PF10405.11, score=85.1]; Rad4 beta-hairpin domain 2 [PF10404.11, score=58.3]; Rad4 beta-hairpin domain 1 [PF10403.11, score=54.1]; Rad4 transglutaminase-like domain [PF03835.17, score=50.1]} {Human: ENSG00000154767, XPC, XPC complex subunit, DNA damage recognition and repair factor, [RH, Score=292, Expect=5e-84]} {Mouse: ENSMUSG00000030094, Xpc, xeroderma pigmentosum, complementation group C, [RH, Score=302, Expect=6e-88]} {Dmel: FBgn0004698, Xpc, Xeroderma pigmentosum, complementation group C, [RH, Score=296, Expect=3e-84]} {Celegans: WBGene00022296, xpc-1, XPC (Xeroderma Pigmentosum group C) DNA repair gene homolog, [RH, Score=231, Expect=1e-62]} {Smed: dd_Smed_v6_5100_0_1, dd_Smed_v6_5100_0_1, [RH, Score=236, Expect=3e-67]} {RNA1509_22240, RNA1509_37174, RNA1509_43141} {RNA1310_2636, RNA1509_22240, RNA1509_37174, RNA1509_43141} {RNA1509_22240, RNA1509_37174, RNA1509_43141, RNA815_7190.1}

Mlig455_031329 {REF} {Length: 3756} {TRANSSPLICED} {Pfam: Rad4 beta-hairpin domain 3 [PF10405.11, score=84.0]; Rad4 beta-hairpin domain 2 [PF10404.11, score=58.3]; Rad4 beta-hairpin domain 1 [PF10403.11, score=52.6]; Rad4 transglutaminase-like domain [PF03835.17, score=50.2]} {Human: ENSG00000154767, XPC, XPC complex subunit, DNA damage recognition and repair factor, [RH, Score=283, Expect=5e-81]} {Mouse: ENSMUSG00000030094, Xpc, xeroderma pigmentosum, complementation group C, [RH, Score=301, Expect=9e-88]} {Dmel: FBgn0004698, Xpc, Xeroderma pigmentosum, complementation group C, [RH, Score=296, Expect=2e-84]} {Celegans: WBGene00022296, xpc-1, XPC (Xeroderma Pigmentosum group C) DNA repair gene homolog, [RH, Score=229, Expect=3e-62]} {Smed: dd_Smed_v6_5100_0_1, dd_Smed_v6_5100_0_1, [RH, Score=237, Expect=2e-67]} {RNA1509_38140} {RNA1310_4273.2} {RNA815_7190.1}
38. MligTC455_27713 2383 49.64 Mlig455_021309

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.591

 GAA 0.95 - - - - - 0.950 Mlig455_021309 {REF} {Length: 3662} {TRANSSPLICED} {Pfam: Glycosyl hydrolases family 31 [PF01055.28, score=486.6]; N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase [PF16863.7, score=52.1]; Galactose mutarotase-like [PF13802.8, score=47.1]; Trefoil (P-type) domain [PF00088.20, score=34.3]} {Human: ENSG00000171298, GAA, glucosidase alpha, acid, [RH, Score=619, Expect=0.0]} {Mouse: ENSMUSG00000025579, Gaa, glucosidase, alpha, acid, [RH, Score=643, Expect=0.0]} {Dmel: FBgn0027588, GCS2alpha, Glucosidase 2 alpha subunit, [Score=260, Expect=2e-73]} {Celegans: WBGene00017071, aagr-1, Acid Alpha Glucosidase Relate, [RH, Score=473, Expect=2e-152]} {Smed: dd_Smed_v6_1062_0_1, dd_Smed_v6_1062_0_1, [RH, Score=621, Expect=0.0]} {RNA1509_16140, RNA1509_6291} {RNA1310_3380.1, RNA1509_16140, RNA1509_6291} {RNA1509_16140, RNA1509_6291, RNA815_1621.1}

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