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Results for MligTC455_21609

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_21609 576 12.00 Mlig455_019995

Neo: -

Age: logFC(26M/2M)=-0.355

Region-enriched R5: 1.448/0.04285

PPEF1 Mlig455_019995 {REF} {Length: 2672} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=91.9]; EF-hand domain pair [PF13499.8, score=82.4]; EF hand [PF00036.34, score=69.9]; EF-hand domain pair [PF13833.8, score=61.5]; EF-hand domain [PF13405.8, score=50.4]; PPP5 TPR repeat region [PF08321.14, score=37.8]; EF hand [PF13202.8, score=34.3]; EF-hand domain [PF14658.8, score=21.5]; IQ calmodulin-binding motif [PF00612.29, score=19.3]} {Human: ENSG00000086717, PPEF1, protein phosphatase with EF-hand domain 1, [RH, Score=555, Expect=0.0]} {Mouse: ENSMUSG00000062168, Ppef1, protein phosphatase with EF hand calcium-binding domain 1, [RH, Score=541, Expect=0.0]} {Dmel: FBgn0265959, rdgC, retinal degeneration C, [RH, Score=553, Expect=0.0]} {Celegans: WBGene00003969, pef-1, Serine/threonine-protein phosphatase with EF-hands pef-1, [RH, Score=625, Expect=0.0]} {Smed: dd_Smed_v6_11874_0_1, dd_Smed_v6_11874_0_1, [RH, Score=719, Expect=0.0]} {RNA1509_5920} {RNA1310_6882.1, RNA1509_5920} {RNA1509_5920, RNA815_2260.1}

Cumulative graph for MligTC455_21609

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 2.692 3.945 0.02395 0.41407
RegionR2 0.162 3.945 0.64267 0.97989
RegionR3 1.29 3.945 0.02650 0.27800
RegionR4 1.254 3.945 0.05567 0.20744
RegionR5 1.448 3.945 0.00663 0.04285
RegionR6 1.187 3.945 0.05101 0.42271
RegionR7 -6.736 3.945 0.00036 0.01588
RegionR8 -1.297 3.945 0.98818 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -8.32 3.945 0.01832 0.55054
RegenerationR2 0.019 3.945 0.96832 1.00000
RegenerationR3 0.338 3.945 0.49686 0.85679
RegenerationR4 0.746 3.945 0.14742 0.57424
RegenerationR5 0.517 3.945 0.25744 0.68935
RegenerationR6 0.815 3.945 0.08879 0.37174
RegenerationBL 2.855 3.945 0.00666 0.07910
RegenerationTP 3.499 3.945 0.02168 0.25069


Genes with expression patterns similar to MligTC455_21609

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_21609 576 12 Mlig455_019995

Neo: -

Age: logFC(26M/2M)=-0.355

Region-enriched R5: 1.448/0.04285

PPEF1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_019995 {REF} {Length: 2672} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=91.9]; EF-hand domain pair [PF13499.8, score=82.4]; EF hand [PF00036.34, score=69.9]; EF-hand domain pair [PF13833.8, score=61.5]; EF-hand domain [PF13405.8, score=50.4]; PPP5 TPR repeat region [PF08321.14, score=37.8]; EF hand [PF13202.8, score=34.3]; EF-hand domain [PF14658.8, score=21.5]; IQ calmodulin-binding motif [PF00612.29, score=19.3]} {Human: ENSG00000086717, PPEF1, protein phosphatase with EF-hand domain 1, [RH, Score=555, Expect=0.0]} {Mouse: ENSMUSG00000062168, Ppef1, protein phosphatase with EF hand calcium-binding domain 1, [RH, Score=541, Expect=0.0]} {Dmel: FBgn0265959, rdgC, retinal degeneration C, [RH, Score=553, Expect=0.0]} {Celegans: WBGene00003969, pef-1, Serine/threonine-protein phosphatase with EF-hands pef-1, [RH, Score=625, Expect=0.0]} {Smed: dd_Smed_v6_11874_0_1, dd_Smed_v6_11874_0_1, [RH, Score=719, Expect=0.0]} {RNA1509_5920} {RNA1310_6882.1, RNA1509_5920} {RNA1509_5920, RNA815_2260.1}
2. MligTC455_19467 366 7.63 Mlig455_064830

Neo: -

Age: -

Region-enriched R4: 2.976/0.00386

TRPM6 3.254 - 0.745 - 0.790 0.766 0.953 Mlig455_064830 {REF} {Length: 6830} {Pfam: SLOG in TRPM [PF18139.3, score=191.7]; SLOG in TRPM, prokaryote [PF18171.3, score=75.5]; Ion transport protein [PF00520.33, score=48.1]} {Human: ENSG00000119121, TRPM6, transient receptor potential cation channel subfamily M member 6, [Score=401, Expect=3e-115]} {Mouse: ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [RH, Score=416, Expect=2e-121]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=402, Expect=2e-119]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=323, Expect=1e-90]} {Smed: dd_Smed_v6_11259_0_12, dd_Smed_v6_11259_0_12, [RH, Score=498, Expect=4e-155]} {RNA1509_8221} {RNA1310_1347, RNA1509_8221} {RNA1509_8221, RNA815_794}
3. MligTC455_46553 1388 28.92 Mlig455_047459

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=1.470

DHCR24 2.667 - - - 0.792 0.924 0.951 Mlig455_047459 {REF} {Length: 2061} {Pfam: FAD binding domain [PF01565.25, score=49.8]} {Human: ENSG00000116133, DHCR24, 24-dehydrocholesterol reductase, [RH, Score=649, Expect=0.0]} {Mouse: ENSMUSG00000034926, Dhcr24, 24-dehydrocholesterol reductase, [RH, Score=643, Expect=0.0]} {Celegans: WBGene00018718, F52H2.6, Diminuto-like protein, [RH, Score=498, Expect=4e-173]} {Smed: dd_Smed_v6_13164_0_1, dd_Smed_v6_13164_0_1, [RH, Score=629, Expect=0.0]} {RNA1509_54118, RNA1509_5458, RNA1509_59230} {RNA1310_12391.1, RNA1509_54118, RNA1509_5458, RNA1509_59230} {RNA1509_54118, RNA1509_5458, RNA1509_59230, RNA815_5116}
4. MligTC455_45275 384 8 Mlig455_037525

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.804

Region-enriched R4: 2.211/0.00561

2.652 - - - 0.864 0.830 0.958 Mlig455_037525 {REF} {Length: 1617} {Pfam: HYD1 signature containing ADP-ribosyltransferase [PF15633.8, score=44.2]} {RNA1509_38410, RNA1509_7973} {RNA1310_28627, RNA1509_38410, RNA1509_7973} {RNA1509_38410, RNA1509_7973, RNA815_9390.1}
5. MligTC455_45333 5039 104.98 Mlig455_024662, Mlig455_048643, Mlig455_068867

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.566/0.00006
Region-enriched R3: 1.419/0.00002

LIPA 2.651 - - - 0.817 0.878 0.956

Mlig455_024662 {REF} {Length: 2228} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}

Mlig455_048643 {REF} {Length: 2232} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}

Mlig455_068867 {REF} {Length: 4154} {TRANSSPLICED} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}
6. MligTC455_37965 2119 44.14 Mlig455_061609

Neo: -

Age: logFC(26M/2M)=-0.234

Region-enriched R4: 1.829/0.00050
Region-enriched R5: 1.117/0.01344

HSD17B4 2.637 - - - 0.777 0.955 0.905 Mlig455_061609 {REF} {Length: 2731} {TRANSSPLICED} {Pfam: short chain dehydrogenase [PF00106.27, score=134.8]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=111.9]; MaoC like domain [PF01575.21, score=97.6]; KR domain [PF08659.12, score=53.8]; SCP-2 sterol transfer family [PF02036.19, score=48.6]} {Human: ENSG00000133835, HSD17B4, hydroxysteroid 17-beta dehydrogenase 4, [RH, Score=778, Expect=0.0]} {Mouse: ENSMUSG00000024507, Hsd17b4, hydroxysteroid (17-beta) dehydrogenase 4, [RH, Score=754, Expect=0.0]} {Dmel: FBgn0030731, Mfe2, peroxisomal Multifunctional enzyme type 2, [RH, Score=591, Expect=0.0]} {Celegans: WBGene00000991, dhs-28, DeHydrogenases, Short chain, [RH, Score=358, Expect=1e-116]} {Smed: dd_Smed_v6_5867_0_1, dd_Smed_v6_5867_0_1, [RH, Score=605, Expect=0.0]} {RNA1509_1653, RNA1509_23131, RNA1509_39124, RNA1509_9012} {RNA1310_590.1, RNA1509_1653, RNA1509_23131, RNA1509_39124, RNA1509_9012} {RNA1509_1653, RNA1509_23131, RNA1509_39124, RNA1509_9012, RNA815_2204}
7. MligTC455_11650 1098 22.87 Mlig455_007133

Neo: -

Age: logFC(26M/2M)=1.455

Region-enriched R4: 2.055/0.00000
Region-enriched R3: 1.617/0.00001
Region-enriched R5: 1.032/0.00532

2.611 - 0.848 - - 0.793 0.970 Mlig455_007133 {REF} {Length: 1372} {Pfam: Tyrosine phosphatase family [PF13350.8, score=133.9]; Tyrosine phosphatase family [PF03162.15, score=32.8]} {Smed: dd_Smed_v6_6110_0_1, dd_Smed_v6_6110_0_1, [RH, Score=96.3, Expect=2e-22]} {RNA1509_24412} {RNA1310_29199} {RNA815_14210.1}
8. MligTC455_45572 697 14.53 Mlig455_014345

Neo: -

Age: -

Region-enriched R4: 2.663/0.00001
Region-enriched R3: 1.769/0.00087
Region-enriched R5: 1.541/0.00135
Region-enriched R6: 1.390/0.04169

CRYL1 2.611 - - - 0.849 0.801 0.961 Mlig455_014345 {REF} {Length: 1372} {Pfam: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain [PF02737.20, score=152.8]; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain [PF00725.24, score=40.7]} {Human: ENSG00000165475, CRYL1, crystallin lambda 1, [RH, Score=275, Expect=6e-91]} {Mouse: ENSMUSG00000021947, Cryl1, crystallin, lambda 1, [RH, Score=261, Expect=7e-86]} {Dmel: FBgn0030737, CG9914, [RH, Score=287, Expect=4e-96]} {Celegans: WBGene00022130, Y71F9B.9, [RH, Score=249, Expect=2e-81]} {Smed: dd_Smed_v6_1696_0_1, dd_Smed_v6_1696_0_1, [RH, Score=176, Expect=6e-53]} {RNA1509_34725} {RNA1310_23652} {RNA815_8421.1}
9. MligTC455_16257 1877 39.1 Mlig455_026808, Mlig455_030881

Neo: -

Age: Down-Down-Up

Region-enriched R4: 2.209/0.00209
Region-enriched R3: 1.663/0.01717
Region-enriched R5: 1.364/0.02606

STOM 2.579 - - - 0.793 0.833 0.953

Mlig455_026808 {REF} {Length: 1301} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=20.6]} {Human: ENSG00000148175, STOM, stomatin, [Score=123, Expect=2e-35]; ENSG00000133115, STOML3, stomatin like 3, [Score=118, Expect=1e-33]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=123, Expect=2e-35]; ENSMUSG00000027744, Stoml3, stomatin (Epb7.2)-like 3, [Score=120, Expect=2e-34]; ENSMUSG00000026602, Nphs2, nephrosis 2, podocin, [Score=117, Expect=2e-32]} {Dmel: FBgn0260657, CG42540, [Score=126, Expect=5e-36]} {Celegans: WBGene00006068, sto-6, STOmatin, [Score=140, Expect=1e-42]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=148, Expect=1e-45]} {RNA1509_6816} {RNA1310_26895} {RNA815_11983}

Mlig455_030881 {REF} {Length: 1405} {Pfam: SPFH domain / Band 7 family [PF01145.27, score=110.3]; SPFH domain-Band 7 family [PF13421.8, score=20.7]} {Human: ENSG00000148175, STOM, stomatin, [Score=335, Expect=3e-115]} {Mouse: ENSMUSG00000026880, Stom, stomatin, [Score=323, Expect=5e-111]} {Dmel: FBgn0260657, CG42540, [Score=323, Expect=2e-109]} {Celegans: WBGene00003166, mec-2, Mechanosensory protein 2, [Score=335, Expect=4e-114]} {Smed: dd_Smed_v6_6396_0_1, dd_Smed_v6_6396_0_1, [Score=362, Expect=1e-126]} {RNA1509_6816} {RNA1310_26895, RNA1509_6816} {RNA1509_6816, RNA815_11983}
10. MligTC455_35633 4966 103.45 Mlig455_048471

Neo: -

Age: -

Region-enriched R4: 1.579/0.00682
Region-enriched R3: 1.493/0.00762

DHDH 2.476 - - - 0.760 0.758 0.958 Mlig455_048471 {REF} {Length: 1491} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=87.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]; Homoserine dehydrogenase, NAD binding domain [PF03447.18, score=19.9]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=246, Expect=3e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=248, Expect=4e-80]} {Dmel: FBgn0031418, CG3609, [RH, Score=231, Expect=1e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=213, Expect=9e-67]} {RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1310_24236, RNA1509_1049, RNA1509_4889, RNA1509_8979} {RNA1509_1049, RNA1509_4889, RNA1509_8979, RNA815_11111.1}
11. MligTC455_39350 538 11.21 Mlig455_023484

Neo: -

Age: Down-Up-Down

Region-enriched R4: 3.492/0.00082
Region-enriched R5: 2.753/0.00156

RAB8B 1.855 - - - 0.955 0.900 - Mlig455_023484 {REF} {Length: 1074} {Pfam: Ras family [PF00071.24, score=174.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=108.8]; ADP-ribosylation factor family [PF00025.23, score=55.3]; 50S ribosome-binding GTPase [PF01926.25, score=32.2]; Gtr1/RagA G protein conserved region [PF04670.14, score=27.8]; Signal recognition particle receptor beta subunit [PF09439.12, score=23.5]; RsgA GTPase [PF03193.18, score=22.5]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=152, Expect=1e-45]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=146, Expect=1e-43]; ENSG00000143545, RAB13, RAB13, member RAS oncogene family, [Score=145, Expect=2e-43]; ENSG00000285641, AL358472.6, novel protein, [Score=145, Expect=2e-43]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=152, Expect=6e-46]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=149, Expect=1e-44]; ENSMUSG00000027935, Rab13, RAB13, member RAS oncogene family, [Score=147, Expect=3e-44]; ENSMUSG00000020732, Rab37, RAB37, member RAS oncogene family, [Score=145, Expect=5e-43]} {Dmel: FBgn0262518, Rab8, [Score=147, Expect=5e-44]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=147, Expect=2e-44]} {Smed: dd_Smed_v6_9518_0_2, dd_Smed_v6_9518_0_2, [RH, Score=167, Expect=5e-52]} {RNA1509_19859, RNA1509_27459} {RNA1310_37116, RNA1509_27459} {RNA1509_27459, RNA815_17007}
12. MligTC455_48110 372 7.74 Mlig455_056044, Mlig455_061610

Neo: -

Age: -

Region-enriched R2: 2.405/0.02438

1.823 0.861 - - 0.962 - -

Mlig455_056044 {REF} {Length: 251} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45490} {RNA1310_117372.1} {RNA815_2204}

Mlig455_061610 {REF} {Length: 251} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45490} {RNA1310_117372.1, RNA1509_45490} {RNA1509_45490, RNA815_2204}
13. MligTC455_19080 969 20.19 Mlig455_033341

Neo: -

Age: Up-Down-Down

Region-enriched R5: 1.378/0.02877

1.818 - - - - 0.849 0.969 Mlig455_033341 {REF} {Length: 1009} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_41133} {RNA1310_2059.1} {RNA815_20560.2}
14. MligTC455_17186 498 10.38 Mlig455_066319

Neo: -

Age: -

Region-enriched R4: 3.693/0.00006
Region-enriched R3: 2.735/0.00030
Region-enriched R5: 2.267/0.00198

1.813 - - - 0.832 - 0.981 Mlig455_066319 {REF} {Length: 2762} {Pfam: YhhN family [PF07947.16, score=79.2]} {Dmel: FBgn0039681, CG7582, [Score=52.8, Expect=5e-08]} {Smed: dd_Smed_v6_11970_0_1, dd_Smed_v6_11970_0_1, [Score=64.3, Expect=2e-12]} {RNA1509_17539, RNA1509_20437, RNA1509_26581, RNA1509_28364} {RNA1310_11695.1, RNA1509_17539, RNA1509_20437, RNA1509_26581, RNA1509_28364} {RNA1509_17539, RNA1509_20437, RNA1509_26581, RNA1509_28364, RNA815_14610}
15. MligTC455_52980 741 15.43 Mlig455_063255, Mlig455_063281

Neo: -

Age: -

DHCR7 1.8 - - - 0.842 - 0.958

Mlig455_063255 {REF} {Length: 1770} {Pfam: Ergosterol biosynthesis ERG4/ERG24 family [PF01222.19, score=222.7]} {Human: ENSG00000172893, DHCR7, 7-dehydrocholesterol reductase, [RH, Score=228, Expect=3e-69]} {Mouse: ENSMUSG00000058454, Dhcr7, 7-dehydrocholesterol reductase, [RH, Score=227, Expect=8e-69]} {Celegans: WBGene00007126, dhcr-7, DeHydroCholesterol Reductase; Sterol reductase, [RH, Score=138, Expect=3e-36]} {Smed: dd_Smed_v6_8591_0_1, dd_Smed_v6_8591_0_1, [RH, Score=369, Expect=2e-124]} {RNA1509_37450} {RNA1310_19926.1} {RNA815_14026}

Mlig455_063281 {REF} {Length: 1871} {Pfam: Ergosterol biosynthesis ERG4/ERG24 family [PF01222.19, score=222.2]} {Human: ENSG00000172893, DHCR7, 7-dehydrocholesterol reductase, [RH, Score=226, Expect=1e-68]} {Mouse: ENSMUSG00000058454, Dhcr7, 7-dehydrocholesterol reductase, [RH, Score=225, Expect=4e-68]} {Celegans: WBGene00007126, dhcr-7, DeHydroCholesterol Reductase; Sterol reductase, [RH, Score=141, Expect=3e-37]} {Smed: dd_Smed_v6_8591_0_1, dd_Smed_v6_8591_0_1, [RH, Score=370, Expect=7e-125]} {RNA1509_37450} {RNA1310_19926.1} {RNA815_14026}
16. MligTC455_25125 578 12.04 Mlig455_008191

Neo: -

Age: -

Region-enriched R4: 3.458/0.00027

1.75 - - - 0.799 - 0.951 Mlig455_008191 {REF} {Length: 1118} {RNA1509_16045, RNA1509_52634, RNA1509_59237} {RNA1310_35530.2, RNA1509_52634, RNA1509_59237} {RNA1509_52634, RNA1509_59237, RNA815_17294.1}
17. MligTC455_39261 2000 41.67 Mlig455_036509, Mlig455_069140

Neo: -

Age: logFC(26M/2M)=-0.812

1.72 - - - 0.764 - 0.956

Mlig455_036509 {REF} {Length: 2142} {RNA1509_28747} {RNA1310_48185.2} {RNA815_28254}

Mlig455_069140 {REF} {Length: 3743} {RNA1509_28747, RNA1509_33325, RNA1509_34343} {RNA1310_46864, RNA1509_28747, RNA1509_33325, RNA1509_34343} {RNA1509_28747, RNA1509_33325, RNA1509_34343, RNA815_28254}
18. MligTC455_27835 1363 28.4 Mlig455_048346

Neo: -

Age: -

Region-enriched R5: 1.320/0.00621

Regeneration-upregulated BL: 1.968

Regeneration-enriched BL: 1.968

OPLAH 1.66 - - - 0.950 0.710 - Mlig455_048346 {REF} {Length: 14868} {TRANSSPLICED} {Pfam: Hydantoinase B/oxoprolinase [PF02538.16, score=677.6]; Hydantoinase/oxoprolinase [PF01968.20, score=348.4]; Hydantoinase/oxoprolinase N-terminal region [PF05378.15, score=172.3]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=128.4]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=113.3]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=76.9]; Integrase zinc binding domain [PF17921.3, score=68.9]; Aspartyl protease [PF13650.8, score=38.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=35.2]; Hydantoinase/oxoprolinase C-terminal domain [PF19278.1, score=25.9]; Retroviral aspartyl protease [PF00077.22, score=24.3]; Aspartyl protease [PF09668.12, score=23.4]; Putative peptidase (DUF1758) [PF05585.14, score=21.1]} {Human: ENSG00000178814, OPLAH, 5-oxoprolinase, ATP-hydrolysing, [Score=800, Expect=0.0]} {Mouse: ENSMUSG00000022562, Oplah, 5-oxoprolinase (ATP-hydrolysing), [Score=779, Expect=0.0]} {Dmel: FBgn0034733, CG4752, [Score=757, Expect=0.0]} {Celegans: WBGene00021430, Y38F2AR.12, [Score=763, Expect=0.0]} {Smed: dd_Smed_v6_5008_0_1, dd_Smed_v6_5008_0_1, [Score=847, Expect=0.0]} {RNA1509_20493} {RNA1310_131.1} {RNA815_52.1}
19. MligTC455_19589 1267 26.39 Mlig455_019782, Mlig455_019805

Neo: -

Age: Down-Down-Up

Region-enriched R3: 2.513/0.00008
Region-enriched R4: 2.414/0.00063
Region-enriched R5: 2.371/0.00008
Region-enriched R6: 1.844/0.03273

1.654 - - - - 0.704 0.950

Mlig455_019782 {REF} {Length: 858} {RNA1509_20360} {RNA1310_37068} {RNA815_23648}

Mlig455_019805 {REF} {Length: 869} {RNA1509_20360, RNA1509_54648} {RNA1310_37068, RNA1509_54648} {RNA1509_54648, RNA815_23648}
20. MligTC455_54257 918 19.13 Mlig455_031742

Neo: -

Age: Down-Down-Up

PHEX 0.982 - - - - - 0.982 Mlig455_031742 {REF} {Length: 5124} {Pfam: Peptidase family M13 [PF01431.23, score=155.4]; Peptidase family M13 [PF05649.15, score=65.6]} {Human: ENSG00000102174, PHEX, phosphate regulating endopeptidase homolog X-linked, [Score=167, Expect=1e-42]; ENSG00000196549, MME, membrane metalloendopeptidase, [Score=161, Expect=9e-41]; ENSG00000117298, ECE1, endothelin converting enzyme 1, [Score=159, Expect=6e-40]} {Mouse: ENSMUSG00000027820, Mme, membrane metallo endopeptidase, [Score=160, Expect=1e-40]; ENSMUSG00000057530, Ece1, endothelin converting enzyme 1, [Score=159, Expect=3e-40]; ENSMUSG00000058183, Mmel1, membrane metallo-endopeptidase-like 1, [Score=158, Expect=7e-40]} {Dmel: FBgn0029843, Nep1, Neprilysin 1, [Score=175, Expect=3e-45]} {Celegans: WBGene00020230, nep-2, Neprilysin-2, [Score=189, Expect=1e-50]} {Smed: dd_Smed_v6_1910_0_1, dd_Smed_v6_1910_0_1, [Score=154, Expect=6e-39]} {RNA1509_11761, RNA1509_23289, RNA1509_23655} {RNA1310_3949, RNA1509_11761, RNA1509_23289, RNA1509_23655} {RNA1509_11761, RNA1509_23289, RNA1509_23655, RNA815_1001.1}
21. MligTC455_51191 1313 27.36 Mlig455_016821, Mlig455_065936

Neo: -

Age: -

Region-enriched R3: 2.457/0.00000

0.968 - - - - - 0.968

Mlig455_016821 {REF} {Length: 1690} {Pfam: Innexin [PF00876.20, score=237.0]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=66.6, Expect=6e-12]} {Celegans: WBGene00002135, inx-13, Innexin, [Score=189, Expect=7e-57]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=202, Expect=2e-61]} {RNA1509_34498} {RNA1310_9582, RNA1509_34498} {RNA1509_34498, RNA815_10664}

Mlig455_065936 {REF} {Length: 2463} {Pfam: Innexin [PF00876.20, score=323.0]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=89.7, Expect=1e-19]} {Celegans: WBGene00002123, inx-1, Innexin, [Score=260, Expect=2e-83]} {Smed: dd_Smed_v6_734_0_1, dd_Smed_v6_734_0_1, [Score=276, Expect=2e-89]} {RNA1509_22191, RNA1509_51923} {RNA1310_9582, RNA1509_22191, RNA1509_51923} {RNA1509_22191, RNA1509_51923, RNA815_10664}
22. MligTC455_42399 391 8.14 Mlig455_059202

Neo: -

Age: -

NUDT19 0.958 - - - - 0.958 - Mlig455_059202 {REF} {Length: 3927} {Pfam: NUDIX domain [PF00293.30, score=22.8]} {Human: ENSG00000213965, NUDT19, nudix hydrolase 19, [RH, Score=149, Expect=7e-41]} {Mouse: ENSMUSG00000034875, Nudt19, nudix (nucleoside diphosphate linked moiety X)-type motif 19, [RH, Score=149, Expect=3e-41]} {Dmel: FBgn0032790, CG10194, [RH, Score=135, Expect=3e-36]} {Celegans: WBGene00003584, ndx-7, Putative nudix hydrolase 7, [RH, Score=77.8, Expect=6e-16]} {Smed: dd_Smed_v6_14640_0_1, dd_Smed_v6_14640_0_1, [RH, Score=131, Expect=5e-35]} {RNA1509_23705, RNA1509_38189, RNA1509_38689} {RNA1310_23441.1, RNA1509_23705, RNA1509_38189, RNA1509_38689} {RNA1509_23705, RNA1509_38189, RNA1509_38689, RNA815_36540}
23. MligTC455_44838 1113 23.18 Mlig455_035218, Mlig455_035266

Neo: -

Age: -

MAN2B1 0.955 - - - - - 0.955

Mlig455_035218 {REF} {Length: 3151} {Pfam: Glycosyl hydrolases family 38 N-terminal domain [PF01074.24, score=269.2]; Alpha mannosidase middle domain [PF09261.13, score=64.9]; Glycosyl hydrolases family 38 C-terminal domain [PF07748.15, score=44.0]; Glycosyl hydrolases family 38 C-terminal beta sandwich domain [PF17677.3, score=32.3]} {Human: ENSG00000104774, MAN2B1, mannosidase alpha class 2B member 1, [Score=630, Expect=0.0]} {Mouse: ENSMUSG00000005142, Man2b1, mannosidase 2, alpha B1, [Score=607, Expect=0.0]} {Dmel: FBgn0027611, LManII, Lysosomal alpha-mannosidase II, [Score=636, Expect=0.0]} {Celegans: WBGene00018877, aman-1, Alpha-mannosidase, [RH, Score=502, Expect=9e-163]} {Smed: dd_Smed_v6_1942_0_1, dd_Smed_v6_1942_0_1, [Score=674, Expect=0.0]} {RNA1509_7785} {RNA1310_4896.1, RNA1509_7785} {RNA1509_7785, RNA815_7617}

Mlig455_035266 {REF} {Length: 2979} {Pfam: Glycosyl hydrolases family 38 N-terminal domain [PF01074.24, score=189.2]; Alpha mannosidase middle domain [PF09261.13, score=64.8]; Glycosyl hydrolases family 38 C-terminal domain [PF07748.15, score=45.6]; Glycosyl hydrolases family 38 C-terminal beta sandwich domain [PF17677.3, score=32.4]} {Human: ENSG00000104774, MAN2B1, mannosidase alpha class 2B member 1, [Score=531, Expect=1e-173]} {Mouse: ENSMUSG00000005142, Man2b1, mannosidase 2, alpha B1, [Score=501, Expect=6e-162]} {Dmel: FBgn0027611, LManII, Lysosomal alpha-mannosidase II, [Score=538, Expect=2e-175]} {Celegans: WBGene00018877, aman-1, Alpha-mannosidase, [Score=428, Expect=4e-135]} {Smed: dd_Smed_v6_1942_0_1, dd_Smed_v6_1942_0_1, [Score=566, Expect=0.0]} {RNA1509_7785} {RNA1310_4896.1} {RNA815_7617}
24. MligTC455_51957 427 8.9 Mlig455_001616

Neo: -

Age: logFC(26M/2M)=0.792

LCK 0.955 - - - - - 0.955 Mlig455_001616 {REF} {Length: 2834} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=195.1]; Protein kinase domain [PF00069.27, score=130.1]; Variant SH3 domain [PF14604.8, score=43.0]; SH2 domain [PF00017.26, score=42.8]; Variant SH3 domain [PF07653.19, score=36.6]; SH3 domain [PF00018.30, score=35.8]; ABC1 atypical kinase-like domain [PF03109.18, score=28.0]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=251, Expect=7e-78]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=250, Expect=5e-77]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=241, Expect=1e-73]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=255, Expect=4e-79]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=243, Expect=7e-75]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=239, Expect=4e-73]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=213, Expect=5e-64]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=304, Expect=6e-99]} {RNA1509_10615, RNA1509_47356} {RNA1310_9006.1, RNA1509_47356} {RNA1509_47356, RNA815_3005.1}
25. MligTC455_49583 2463 51.31 Mlig455_040789, Mlig455_064625

Neo: -

Age: -

Region-specific R4: 1.786

Region-enriched R4: 1.564/0.00002

UBXN1 0.953 - - - - 0.953 -

Mlig455_040789 {REF} {Length: 1307} {TRANSSPLICED} {Pfam: UBX domain [PF00789.22, score=53.7]} {Human: ENSG00000162191, UBXN1, UBX domain protein 1, [RH, Score=79.0, Expect=3e-16]} {Mouse: ENSMUSG00000071655, Ubxn1, UBX domain protein 1, [RH, Score=99.8, Expect=6e-24]} {Dmel: FBgn0035830, CG8209, [RH, Score=158, Expect=9e-46]} {Celegans: WBGene00017733, ubxn-1, UBX-containing protein in Nematodes, [RH, Score=153, Expect=2e-44]} {Smed: dd_Smed_v6_3619_0_1, dd_Smed_v6_3619_0_1, [RH, Score=160, Expect=4e-47]} {RNA1509_24118, RNA1509_4943} {RNA1310_26309, RNA1509_4943} {RNA1509_4943, RNA815_23834}

Mlig455_064625 {REF} {Length: 1307} {TRANSSPLICED} {Pfam: UBX domain [PF00789.22, score=53.9]} {Human: ENSG00000162191, UBXN1, UBX domain protein 1, [RH, Score=79.0, Expect=3e-16]} {Mouse: ENSMUSG00000071655, Ubxn1, UBX domain protein 1, [RH, Score=99.8, Expect=6e-24]} {Dmel: FBgn0035830, CG8209, [RH, Score=158, Expect=9e-46]} {Celegans: WBGene00017733, ubxn-1, UBX-containing protein in Nematodes, [RH, Score=153, Expect=2e-44]} {Smed: dd_Smed_v6_3619_0_1, dd_Smed_v6_3619_0_1, [RH, Score=159, Expect=2e-46]} {RNA1509_24118} {RNA1310_26309} {RNA815_23834}
26. MligTC455_48472 1609 33.52 Mlig455_025716, Mlig455_025768, Mlig455_064423

Neo: Int S/G2/M

Age: Down-Up-Up, logFC(26M/2M)=0.271

LTV1 0.95 - - - - 0.950 -

Mlig455_025716 {REF} {Length: 1914} {TRANSSPLICED} {Pfam: Low temperature viability protein [PF04180.16, score=40.0]} {Human: ENSG00000135521, LTV1, LTV1 ribosome biogenesis factor, [RH, Score=48.9, Expect=1e-05]} {Mouse: ENSMUSG00000019814, Ltv1, LTV1 ribosome biogenesis factor, [Score=48.5, Expect=1e-05]} {Smed: dd_Smed_v6_2863_0_1, dd_Smed_v6_2863_0_1, [Score=53.1, Expect=2e-07]} {RNA1509_8077} {RNA1310_15034} {RNA815_5643}

Mlig455_025768 {REF} {Length: 1915} {TRANSSPLICED} {Pfam: Low temperature viability protein [PF04180.16, score=38.2]} {Human: ENSG00000135521, LTV1, LTV1 ribosome biogenesis factor, [RH, Score=48.9, Expect=1e-05]} {Mouse: ENSMUSG00000019814, Ltv1, LTV1 ribosome biogenesis factor, [Score=49.3, Expect=7e-06]} {Smed: dd_Smed_v6_2863_0_1, dd_Smed_v6_2863_0_1, [Score=51.2, Expect=7e-07]} {RNA1509_8077} {RNA1310_15034} {RNA815_5643}

Mlig455_064423 {REF} {Length: 1915} {TRANSSPLICED} {Pfam: Low temperature viability protein [PF04180.16, score=37.1]} {Mouse: ENSMUSG00000019814, Ltv1, LTV1 ribosome biogenesis factor, [Score=49.7, Expect=6e-06]} {Smed: dd_Smed_v6_2863_0_1, dd_Smed_v6_2863_0_1, [Score=51.2, Expect=7e-07]} {RNA1509_47697, RNA1509_8077} {RNA1310_15034, RNA1509_47697, RNA1509_8077} {RNA1509_47697, RNA1509_8077, RNA815_5643}
27. MligTC455_53747 1235 25.73 Mlig455_028423

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.445

Regeneration-enriched BL: 1.797
Regeneration-enriched R6: 1.565

THOP1 0.95 - - - - 0.950 - Mlig455_028423 {REF} {Length: 2596} {TRANSSPLICED} {Pfam: Peptidase family M3 [PF01432.22, score=488.7]} {Human: ENSG00000172009, THOP1, thimet oligopeptidase 1, [RH, Score=731, Expect=0.0]} {Mouse: ENSMUSG00000004929, Thop1, thimet oligopeptidase 1, [RH, Score=739, Expect=0.0]} {Dmel: FBgn0039252, CG11771, [RH, Score=166, Expect=5e-43]} {Celegans: WBGene00013464, Y67H2A.7, [Score=97.8, Expect=6e-21]} {Smed: dd_Smed_v6_3546_0_1, dd_Smed_v6_3546_0_1, [RH, Score=603, Expect=0.0]} {RNA1509_2334} {RNA1310_8075.2} {RNA815_3863}

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