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Results for MligTC455_28708

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_28708 2679 55.81 Mlig455_035225

Neo: -

Age: Down-Up-Down

MAPK3 Mlig455_035225 {REF} {Length: 6491} {Pfam: Protein kinase domain [PF00069.27, score=231.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=116.6]; Phosphotransferase enzyme family [PF01636.25, score=19.0]; ABC1 atypical kinase-like domain [PF03109.18, score=18.8]} {Human: ENSG00000102882, MAPK3, mitogen-activated protein kinase 3, [RH, Score=579, Expect=0.0]; ENSG00000100030, MAPK1, mitogen-activated protein kinase 1, [RH, Score=571, Expect=0.0]} {Mouse: ENSMUSG00000063065, Mapk3, mitogen-activated protein kinase 3, [RH, Score=574, Expect=0.0]; ENSMUSG00000063358, Mapk1, mitogen-activated protein kinase 1, [RH, Score=571, Expect=0.0]} {Dmel: FBgn0003256, rl, rolled, [RH, Score=560, Expect=0.0]} {Celegans: WBGene00003401, mpk-1, Mitogen-activated protein kinase mpk-1, [RH, Score=565, Expect=0.0]} {Smed: dd_Smed_v6_9632_0_1, dd_Smed_v6_9632_0_1, [RH, Score=597, Expect=0.0]} {RNA1509_2609} {RNA1310_9680.1} {RNA815_6796.1}

Cumulative graph for MligTC455_28708

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.502 5.775 0.42343 1.00000
RegionR2 -0.272 5.775 0.34461 0.73705
RegionR3 -0.139 5.775 0.56713 1.00000
RegionR4 0.323 5.775 0.23119 0.52426
RegionR5 0.362 5.775 0.09809 0.30111
RegionR6 0.178 5.775 0.45957 1.00000
RegionR7 -0.028 5.775 0.92887 1.00000
RegionR8 0.079 5.775 0.84214 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.132 5.775 0.11258 0.83696
RegenerationR2 0.554 5.775 0.02881 0.27985
RegenerationR3 0.254 5.775 0.34653 0.76922
RegenerationR4 0.017 5.775 0.94975 1.00000
RegenerationR5 0.342 5.775 0.16822 0.59524
RegenerationR6 0.346 5.775 0.19788 0.53828
RegenerationBL 0.275 5.775 0.34708 0.71444
RegenerationTP 0.309 5.775 0.35156 0.79316


Genes with expression patterns similar to MligTC455_28708

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_28708 2679 55.81 Mlig455_035225

Neo: -

Age: Down-Up-Down

MAPK3 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_035225 {REF} {Length: 6491} {Pfam: Protein kinase domain [PF00069.27, score=231.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=116.6]; Phosphotransferase enzyme family [PF01636.25, score=19.0]; ABC1 atypical kinase-like domain [PF03109.18, score=18.8]} {Human: ENSG00000102882, MAPK3, mitogen-activated protein kinase 3, [RH, Score=579, Expect=0.0]; ENSG00000100030, MAPK1, mitogen-activated protein kinase 1, [RH, Score=571, Expect=0.0]} {Mouse: ENSMUSG00000063065, Mapk3, mitogen-activated protein kinase 3, [RH, Score=574, Expect=0.0]; ENSMUSG00000063358, Mapk1, mitogen-activated protein kinase 1, [RH, Score=571, Expect=0.0]} {Dmel: FBgn0003256, rl, rolled, [RH, Score=560, Expect=0.0]} {Celegans: WBGene00003401, mpk-1, Mitogen-activated protein kinase mpk-1, [RH, Score=565, Expect=0.0]} {Smed: dd_Smed_v6_9632_0_1, dd_Smed_v6_9632_0_1, [RH, Score=597, Expect=0.0]} {RNA1509_2609} {RNA1310_9680.1} {RNA815_6796.1}
2. MligTC455_20542 5447 113.47 Mlig455_003023, Mlig455_003318

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.611

Region-enriched R8: 1.173/0.00545

KY 1.721 - - - 0.952 - 0.769

Mlig455_003023 {REF} {Length: 19522} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=22.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=79.7, Expect=1e-13]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=77.8, Expect=3e-13]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=103, Expect=4e-21]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=90.5, Expect=2e-17]} {Smed: dd_Smed_v6_1109_0_1, dd_Smed_v6_1109_0_1, [Score=290, Expect=4e-80]} {RNA1509_704} {RNA1310_3180} {RNA815_1159.1}

Mlig455_003318 {REF} {Length: 19222} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=22.9]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=80.5, Expect=7e-14]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=75.5, Expect=2e-12]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=99.8, Expect=5e-20]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=90.9, Expect=1e-17]} {Smed: dd_Smed_v6_1109_0_1, dd_Smed_v6_1109_0_1, [Score=292, Expect=8e-81]} {RNA1509_2987, RNA1509_37803, RNA1509_704} {RNA1310_3180, RNA1509_2987, RNA1509_37803} {RNA1509_2987, RNA1509_37803, RNA815_1159.1}
3. MligTC455_32487 595 12.39 Mlig455_017119

Neo: -

Age: logFC(26M/2M)=-0.391

1.716 - 0.764 - 0.952 - - Mlig455_017119 {REF} {Length: 2322} {RNA1509_10657} {RNA1310_11689, RNA1509_10657} {RNA1509_10657, RNA815_5499}
4. MligTC455_16013 376 7.82 Mlig455_002828

Neo: Irradiation

Age: logFC(26M/2M)=0.279

Region-enriched R5: 3.139/0.00000

CCDC102B 1.694 - - - 0.951 - 0.743 Mlig455_002828 {REF} {Length: 3370} {TRANSSPLICED} {Human: ENSG00000150636, CCDC102B, coiled-coil domain containing 102B, [Score=78.2, Expect=6e-15]} {Mouse: ENSMUSG00000063605, Ccdc102a, coiled-coil domain containing 102A, [Score=75.5, Expect=1e-13]} {Dmel: FBgn0051638, CG31638, [Score=89.7, Expect=3e-18]} {Celegans: WBGene00018763, F53F10.1, [Score=75.9, Expect=4e-15]} {Smed: dd_Smed_v6_13699_0_1, dd_Smed_v6_13699_0_1, [RH, Score=82.0, Expect=1e-16]} {RNA1509_8054} {RNA1310_7176} {RNA815_2237}
5. MligTC455_15871 954 19.86 Mlig455_044647

Neo: -

Age: logFC(26M/2M)=0.433

SRD5A1 1.686 - - - 0.964 - 0.722 Mlig455_044647 {REF} {Length: 923} {Pfam: 3-oxo-5-alpha-steroid 4-dehydrogenase [PF02544.18, score=164.6]; Protein of unknown function (DUF1295) [PF06966.14, score=18.2]} {Human: ENSG00000145545, SRD5A1, steroid 5 alpha-reductase 1, [Score=166, Expect=5e-51]; ENSG00000277893, SRD5A2, steroid 5 alpha-reductase 2, [Score=163, Expect=6e-50]} {Mouse: ENSMUSG00000021594, Srd5a1, steroid 5 alpha-reductase 1, [Score=190, Expect=1e-60]} {Dmel: FBgn0032014, CG7840, [Score=54.7, Expect=6e-09]} {Celegans: WBGene00009635, F42F12.3, [Score=141, Expect=8e-42]} {Smed: dd_Smed_v6_11914_0_1, dd_Smed_v6_11914_0_1, [Score=154, Expect=5e-47]} {RNA1509_34393} {RNA1310_18838.2} {RNA815_12433.1}
6. MligTC455_18885 702 14.63 Mlig455_043086

Neo: -

Age: -

Region-enriched R5: 1.483/0.00503

0.982 - - - 0.982 - - Mlig455_043086 {REF} {Length: 1459} {TRANSSPLICED} {Pfam: Protein phosphatase 1 regulatory subunit 35 C-terminus [PF15503.8, score=21.6]} {RNA1509_29701, RNA1509_42732} {RNA1310_24161, RNA1509_29701, RNA1509_42732} {RNA1509_29701, RNA1509_42732, RNA815_18643}
7. MligTC455_43400 2448 51 Mlig455_042374, Mlig455_043600

Neo: -

Age: logFC(26M/2M)=-0.280

PRKAR2A 0.978 - - - 0.978 - -

Mlig455_042374 {REF} {Length: 3412} {TRANSSPLICED} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=134.7]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=55.4]} {Human: ENSG00000114302, PRKAR2A, protein kinase cAMP-dependent type II regulatory subunit alpha, [Score=311, Expect=2e-102]} {Mouse: ENSMUSG00000032601, Prkar2a, protein kinase, cAMP dependent regulatory, type II alpha, [Score=314, Expect=7e-104]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [Score=318, Expect=1e-105]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=227, Expect=6e-71]} {Smed: dd_Smed_v6_4188_0_1, dd_Smed_v6_4188_0_1, [Score=337, Expect=2e-113]} {RNA1509_34018, RNA1509_3885} {RNA1310_3950, RNA1509_34018} {RNA1509_34018, RNA815_7205}

Mlig455_043600 {REF} {Length: 3380} {TRANSSPLICED} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=134.8]; Regulatory subunit of type II PKA R-subunit [PF02197.19, score=55.4]} {Human: ENSG00000114302, PRKAR2A, protein kinase cAMP-dependent type II regulatory subunit alpha, [Score=311, Expect=1e-102]} {Mouse: ENSMUSG00000032601, Prkar2a, protein kinase, cAMP dependent regulatory, type II alpha, [Score=314, Expect=8e-104]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [Score=318, Expect=1e-105]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=227, Expect=6e-71]} {Smed: dd_Smed_v6_4188_0_1, dd_Smed_v6_4188_0_1, [Score=337, Expect=2e-113]} {RNA1509_3885, RNA1509_47776, RNA1509_52007} {RNA1310_3950, RNA1509_3885, RNA1509_47776, RNA1509_52007} {RNA1509_3885, RNA1509_47776, RNA1509_52007, RNA815_7205}
8. MligTC455_20371 299 6.22 Mlig455_046384, Mlig455_046452

Neo: -

Age: -

0.965 - - - 0.965 - -

Mlig455_046384 {REF} {Length: 3134} {TRANSSPLICED} {Pfam: Family of unknown function (DUF5537) [PF17690.3, score=18.3]} {RNA1509_52911} {RNA1310_24791} {RNA815_28268}

Mlig455_046452 {REF} {Length: 938} {Pfam: Family of unknown function (DUF5537) [PF17690.3, score=20.6]} {RNA1310_24791} {RNA815_28268}
9. MligTC455_44349 1054 21.95 Mlig455_038043

Neo: -

Age: Down-Up-Up

0.965 - - - 0.965 - - Mlig455_038043 {REF} {Length: 1524} {TRANSSPLICED} {Pfam: Rel homology DNA-binding domain [PF00554.24, score=53.9]} {RNA1509_27212, RNA1509_57165} {RNA1310_20155, RNA1509_27212, RNA1509_57165} {RNA1509_27212, RNA1509_57165, RNA815_8547.1}
10. MligTC455_25229 742 15.47 Mlig455_041688

Neo: -

Age: -

PGAM5 0.964 - - - 0.964 - - Mlig455_041688 {REF} {Length: 2463} {TRANSSPLICED} {Pfam: Histidine phosphatase superfamily (branch 1) [PF00300.24, score=77.2]} {Human: ENSG00000247077, PGAM5, PGAM family member 5, mitochondrial serine/threonine protein phosphatase, [Score=209, Expect=4e-66]} {Mouse: ENSMUSG00000029500, Pgam5, phosphoglycerate mutase family member 5, [Score=209, Expect=2e-66]} {Dmel: FBgn0023517, Pgam5, Phosphoglycerate mutase 5, [Score=207, Expect=6e-66]} {Celegans: WBGene00019941, pgam-5, Serine/threonine-protein phosphatase Pgam5, mitochondrial, [Score=213, Expect=5e-68]} {Smed: dd_Smed_v6_6516_0_1, dd_Smed_v6_6516_0_1, [RH, Score=206, Expect=5e-66]} {RNA1509_9435} {RNA1310_36858, RNA1509_9435} {RNA1509_9435, RNA815_18630}
11. MligTC455_50218 1123 23.39 Mlig455_052752

Neo: -

Age: -

ADPRH 0.962 - - - 0.962 - - Mlig455_052752 {REF} {Length: 1685} {TRANSSPLICED} {Pfam: ADP-ribosylglycohydrolase [PF03747.16, score=160.2]} {Human: ENSG00000144843, ADPRH, ADP-ribosylarginine hydrolase, [RH, Score=266, Expect=6e-87]} {Mouse: ENSMUSG00000002844, Adprh, ADP-ribosylarginine hydrolase, [RH, Score=265, Expect=2e-86]; ENSMUSG00000031448, Adprhl1, ADP-ribosylhydrolase like 1, [RH, Score=255, Expect=6e-83]} {RNA1509_23003, RNA1509_40817, RNA1509_45376, RNA1509_54080} {RNA1310_19299.1, RNA1509_23003, RNA1509_40817, RNA1509_45376, RNA1509_54080} {RNA1509_23003, RNA1509_40817, RNA1509_45376, RNA1509_54080, RNA815_8460}
12. MligTC455_52143 317 6.6 Mlig455_059304

Neo: -

Age: -

CETN3 0.962 - - - 0.962 - - Mlig455_059304 {REF} {Length: 795} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=70.6]; EF hand [PF00036.34, score=61.4]; EF-hand domain pair [PF13833.8, score=60.8]; EF-hand domain [PF13405.8, score=49.6]; EF hand [PF13202.8, score=33.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=23.9]; EF-hand domain [PF17959.3, score=21.9]; Caleosin related protein [PF05042.15, score=19.1]} {Human: ENSG00000153140, CETN3, centrin 3, [Score=205, Expect=6e-68]} {Mouse: ENSMUSG00000021537, Cetn3, centrin 3, [Score=205, Expect=3e-68]} {Dmel: FBgn0040010, CG17493, [Score=123, Expect=7e-36]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=81.6, Expect=3e-20]} {Smed: dd_Smed_v6_11582_0_1, dd_Smed_v6_11582_0_1, [Score=181, Expect=3e-59]} {RNA1509_5944} {RNA1310_28289.1} {RNA815_14129}
13. MligTC455_49396 157 3.27 Mlig455_018614

Neo: -

Age: -

TNN 0.96 - - - 0.960 - - Mlig455_018614 {REF} {Length: 1533} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=113.4]} {Human: ENSG00000120332, TNN, tenascin N, [Score=107, Expect=2e-25]} {Mouse: ENSMUSG00000026725, Tnn, tenascin N, [Score=108, Expect=3e-26]} {Dmel: FBgn0050280, CG30280, [Score=95.9, Expect=4e-23]} {Celegans: WBGene00020516, T15B7.1, [Score=60.5, Expect=2e-10]} {RNA1310_79803} {RNA815_40596}
14. MligTC455_17539 396 8.24 Mlig455_020650

Neo: -

Age: logFC(26M/2M)=-0.311

RPGRIP1L 0.958 - - - 0.958 - - Mlig455_020650 {REF} {Length: 4523} {TRANSSPLICED} {Pfam: First C2 domain of RPGR-interacting protein 1 [PF11618.10, score=156.0]; Retinitis pigmentosa G-protein regulator interacting C-terminal [PF18111.3, score=63.1]; C2 domain [PF00168.32, score=39.2]} {Human: ENSG00000103494, RPGRIP1L, RPGRIP1 like, [RH, Score=486, Expect=3e-150]} {Mouse: ENSMUSG00000033282, Rpgrip1l, Rpgrip1-like, [Score=448, Expect=3e-136]} {Smed: dd_Smed_v6_11425_0_1, dd_Smed_v6_11425_0_1, [RH, Score=489, Expect=2e-151]} {RNA1509_17201, RNA1509_3677, RNA1509_51934} {RNA1310_2541.1, RNA1509_17201, RNA1509_3677, RNA1509_51934} {RNA1509_17201, RNA1509_3677, RNA1509_51934, RNA815_452}
15. MligTC455_19976 1008 21 Mlig455_006463

Neo: -

Age: logFC(26M/2M)=-0.227

NGEF 0.958 - - - 0.958 - - Mlig455_006463 {REF} {Length: 5393} {Pfam: RhoGEF domain [PF00621.22, score=103.1]; SH3 domain [PF00018.30, score=45.6]; Variant SH3 domain [PF07653.19, score=43.7]; Variant SH3 domain [PF14604.8, score=38.2]} {Human: ENSG00000066248, NGEF, neuronal guanine nucleotide exchange factor, [RH, Score=226, Expect=3e-64]; ENSG00000130762, ARHGEF16, Rho guanine nucleotide exchange factor 16, [RH, Score=224, Expect=1e-62]; ENSG00000114790, ARHGEF26, Rho guanine nucleotide exchange factor 26, [RH, Score=218, Expect=9e-60]; ENSG00000277101, ARHGEF26, Rho guanine nucleotide exchange factor 26, [RH, Score=218, Expect=9e-60]} {Mouse: ENSMUSG00000026259, Ngef, neuronal guanine nucleotide exchange factor, [RH, Score=231, Expect=2e-65]} {Dmel: FBgn0261547, Exn, Ephexin, [RH, Score=214, Expect=2e-58]} {Celegans: WBGene00019487, ephx-1, EPHeXin (Eph-interacting GEF) homolog, [Score=215, Expect=2e-60]} {Smed: dd_Smed_v6_1847_0_10, dd_Smed_v6_1847_0_10, [RH, Score=184, Expect=3e-49]} {RNA1509_5926} {RNA1310_1816.1} {RNA815_898.1}
16. MligTC455_30919 296 6.16 Mlig455_027919

Neo: -

Age: -

TNN 0.958 - - - 0.958 - - Mlig455_027919 {REF} {Length: 2245} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.7]} {Human: ENSG00000120332, TNN, tenascin N, [Score=68.2, Expect=1e-11]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=66.6, Expect=3e-11]} {Mouse: ENSMUSG00000026725, Tnn, tenascin N, [Score=66.2, Expect=3e-11]; ENSMUSG00000015829, Tnr, tenascin R, [Score=64.3, Expect=2e-10]} {Dmel: FBgn0031804, CG9500, [Score=81.3, Expect=4e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=68.9, Expect=2e-12]} {RNA1509_53291} {RNA1310_21728} {RNA815_9881}
17. MligTC455_33667 5958 124.13 Mlig455_007432, Mlig455_009113, Mlig455_018420, Mlig455_018422, Mlig455_019321, Mlig455_019779, Mlig455_022265, Mlig455_030138, Mlig455_039042, Mlig455_044740, Mlig455_046763, Mlig455_048838, Mlig455_070035

Neo: -

Age: logFC(26M/2M)=-0.692

0.956 - - - 0.956 - -

Mlig455_007432 {REF} {Length: 4106} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_38197} {RNA1310_15214.1, RNA1509_38197} {RNA1509_38197, RNA815_16073}

Mlig455_009113 {REF} {Length: 798} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_31113} {RNA815_16073}

Mlig455_018420 {REF} {Length: 1199} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_23746} {RNA815_16073}

Mlig455_018422 {REF} {Length: 782} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_31113} {RNA815_16073}

Mlig455_019321 {REF} {Length: 772} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_31113} {RNA815_16073}

Mlig455_019779 {REF} {Length: 770} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_31113} {RNA815_16073}

Mlig455_022265 {REF} {Length: 730} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_31113} {RNA815_16073}

Mlig455_030138 {REF} {Length: 769} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_31113} {RNA815_16073}

Mlig455_039042 {REF} {Length: 772} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_31113} {RNA815_16073}

Mlig455_044740 {REF} {Length: 744} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_31113} {RNA815_16073}

Mlig455_046763 {REF} {Length: 752} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_31113} {RNA815_16073}

Mlig455_048838 {REF} {Length: 772} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_31113} {RNA815_16073}

Mlig455_070035 {REF} {Length: 730} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25254} {RNA1310_23746} {RNA815_16073}
18. MligTC455_18257 366 7.62 Mlig455_012185

Neo: Irradiation

Age: -

Region-enriched R4: 2.311/0.00852

0.955 - - - 0.955 - - Mlig455_012185 {REF} {Length: 3125} {Pfam: TIR domain [PF13676.8, score=37.5]; 60s Acidic ribosomal protein [PF00428.21, score=20.1]} {Smed: dd_Smed_v6_6002_0_1, dd_Smed_v6_6002_0_1, [Score=168, Expect=8e-47]} {RNA1509_12960} {RNA1310_15918} {RNA815_12246.1}
19. MligTC455_50129 935 19.48 Mlig455_066199, Mlig455_068834

Neo: -

Age: -

BRAF 0.955 - - - 0.955 - -

Mlig455_066199 {REF} {Length: 4134} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=201.8]; Protein kinase domain [PF00069.27, score=178.9]; Raf-like Ras-binding domain [PF02196.17, score=62.7]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=28.8]; Kinase-like [PF14531.8, score=24.2]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [RH, Score=488, Expect=1e-159]} {Mouse: ENSMUSG00000002413, Braf, Braf transforming gene, [RH, Score=486, Expect=3e-159]} {Dmel: FBgn0003079, Raf, Raf oncogene, [RH, Score=374, Expect=1e-116]} {Celegans: WBGene00003030, lin-45, Raf homolog serine/threonine-protein kinase, [RH, Score=342, Expect=6e-104]} {Smed: dd_Smed_v6_10148_0_1, dd_Smed_v6_10148_0_1, [RH, Score=458, Expect=5e-149]} {RNA1509_5530} {RNA1310_8028.1, RNA1509_5530} {RNA1509_5530, RNA815_4195.1}

Mlig455_068834 {REF} {Length: 4180} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=201.0]; Protein kinase domain [PF00069.27, score=178.1]; Raf-like Ras-binding domain [PF02196.17, score=62.7]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=28.8]; Kinase-like [PF14531.8, score=23.0]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [RH, Score=489, Expect=4e-160]} {Mouse: ENSMUSG00000002413, Braf, Braf transforming gene, [RH, Score=488, Expect=7e-160]} {Dmel: FBgn0003079, Raf, Raf oncogene, [RH, Score=373, Expect=2e-116]} {Celegans: WBGene00003030, lin-45, Raf homolog serine/threonine-protein kinase, [RH, Score=342, Expect=5e-104]} {Smed: dd_Smed_v6_10148_0_1, dd_Smed_v6_10148_0_1, [RH, Score=459, Expect=1e-149]} {RNA1509_5530} {RNA1310_9384} {RNA815_4195.1}
20. MligTC455_25230 411 8.57 Mlig455_041763

Neo: -

Age: Down-Up-Down

PGAM5 0.954 - - - 0.954 - - Mlig455_041763 {REF} {Length: 3804} {TRANSSPLICED} {Pfam: Histidine phosphatase superfamily (branch 1) [PF00300.24, score=77.2]} {Human: ENSG00000247077, PGAM5, PGAM family member 5, mitochondrial serine/threonine protein phosphatase, [Score=209, Expect=4e-66]} {Mouse: ENSMUSG00000029500, Pgam5, phosphoglycerate mutase family member 5, [Score=209, Expect=2e-66]} {Dmel: FBgn0023517, Pgam5, Phosphoglycerate mutase 5, [Score=207, Expect=6e-66]} {Celegans: WBGene00019941, pgam-5, Serine/threonine-protein phosphatase Pgam5, mitochondrial, [Score=213, Expect=5e-68]} {Smed: dd_Smed_v6_6516_0_1, dd_Smed_v6_6516_0_1, [RH, Score=206, Expect=5e-66]} {RNA1509_9435} {RNA1310_36858} {RNA815_18630}
21. MligTC455_26862 280 5.84 Mlig455_014582

Neo: -

Age: -

0.953 - - - 0.953 - - Mlig455_014582 {REF} {Length: 3135} {TRANSSPLICED} {RNA1509_33062} {RNA1310_8891.1} {RNA815_1626.1}
22. MligTC455_50128 1288 26.83 Mlig455_028373

Neo: -

Age: -

BRAF 0.953 - - - 0.953 - - Mlig455_028373 {REF} {Length: 4173} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=201.0]; Protein kinase domain [PF00069.27, score=178.1]; Raf-like Ras-binding domain [PF02196.17, score=62.7]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=28.8]; Kinase-like [PF14531.8, score=23.0]} {Human: ENSG00000157764, BRAF, B-Raf proto-oncogene, serine/threonine kinase, [RH, Score=489, Expect=3e-160]} {Mouse: ENSMUSG00000002413, Braf, Braf transforming gene, [RH, Score=488, Expect=7e-160]} {Dmel: FBgn0003079, Raf, Raf oncogene, [RH, Score=373, Expect=2e-116]} {Celegans: WBGene00003030, lin-45, Raf homolog serine/threonine-protein kinase, [RH, Score=342, Expect=5e-104]} {Smed: dd_Smed_v6_10148_0_1, dd_Smed_v6_10148_0_1, [RH, Score=459, Expect=1e-149]} {RNA1509_5530} {RNA1310_8028.1} {RNA815_4195.1}
23. Mlig999021.1 0.952 - - - 0.952 - -
24. MligTC455_20434 128 2.66 Mlig455_033593

Neo: -

Age: Up-Down-Up

URGCP 0.952 - - - 0.952 - - Mlig455_033593 {REF} {Length: 3399} {Pfam: Root hair defective 3 GTP-binding protein (RHD3) [PF05879.14, score=31.0]; Dynamin family [PF00350.25, score=25.2]; 50S ribosome-binding GTPase [PF01926.25, score=19.0]} {Human: ENSG00000106608, URGCP, upregulator of cell proliferation, [Score=131, Expect=2e-30]} {Mouse: ENSMUSG00000078606, Gm4070, predicted gene 4070, [Score=389, Expect=2e-114]; ENSMUSG00000045868, Gvin1, GTPase, very large interferon inducible 1, [Score=389, Expect=4e-114]} {RNA1509_1613} {RNA1310_753} {RNA815_297.1}
25. MligTC455_40998 202 4.21 Mlig455_030227, Mlig455_068004

Neo: -

Age: Down-Up-Up

PRG4 0.952 - - - 0.952 - -

Mlig455_030227 {REF} {Length: 1061} {Mouse: ENSMUSG00000050675, Gp1ba, glycoprotein 1b, alpha polypeptide, [Score=63.9, Expect=8e-11]} {RNA1310_70482}

Mlig455_068004 {REF} {Length: 1488} {Human: ENSG00000116690, PRG4, proteoglycan 4, [RH, Score=55.1, Expect=2e-07]} {Mouse: ENSMUSG00000050675, Gp1ba, glycoprotein 1b, alpha polypeptide, [RH, Score=70.5, Expect=1e-12]} {Dmel: FBgn0052656, Muc11A, Mucin 11A, [Score=56.2, Expect=3e-08]} {RNA1310_70482}
26. MligTC455_46400 754 15.71 Mlig455_009563

Neo: -

Age: -

MAP3K12 0.952 - - - 0.952 - - Mlig455_009563 {REF} {Length: 3805} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=179.7]; Protein kinase domain [PF00069.27, score=158.8]} {Human: ENSG00000139625, MAP3K12, mitogen-activated protein kinase kinase kinase 12, [RH, Score=290, Expect=9e-84]} {Mouse: ENSMUSG00000023050, Map3k12, mitogen-activated protein kinase kinase kinase 12, [RH, Score=290, Expect=1e-83]} {Dmel: FBgn0036896, wnd, wallenda, [RH, Score=263, Expect=6e-74]} {Celegans: WBGene00001008, dlk-1, Mitogen-activated protein kinase kinase kinase dlk-1, [Score=233, Expect=3e-66]} {Smed: dd_Smed_v6_8838_0_1, dd_Smed_v6_8838_0_1, [RH, Score=237, Expect=5e-65]} {RNA1509_42265, RNA1509_56503, RNA1509_8182} {RNA1310_2912, RNA1509_42265, RNA1509_56503, RNA1509_8182} {RNA1509_42265, RNA1509_56503, RNA1509_8182, RNA815_3381.1}
27. MligTC455_03382 210 4.37 Mlig455_057035

Neo: -

Age: -

Region-enriched R2: 3.628/0.00113

PDE1C 0.95 - - - 0.950 - - Mlig455_057035 {REF} {Length: 2458} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=275.1]; 3'5'-cyclic nucleotide phosphodiesterase N-terminal [PF08499.14, score=94.2]} {Human: ENSG00000154678, PDE1C, phosphodiesterase 1C, [RH, Score=546, Expect=0.0]} {Mouse: ENSMUSG00000004347, Pde1c, phosphodiesterase 1C, [RH, Score=546, Expect=0.0]} {Dmel: FBgn0264815, Pde1c, Phosphodiesterase 1c, [RH, Score=538, Expect=0.0]} {Celegans: WBGene00011433, pde-1, Probable 3',5'-cyclic phosphodiesterase pde-1, [RH, Score=482, Expect=2e-164]} {Smed: dd_Smed_v6_11039_0_2, dd_Smed_v6_11039_0_2, [RH, Score=613, Expect=0.0]} {RNA1509_46084} {RNA1310_8143.1} {RNA815_6002}
28. MligTC455_16638 2494 51.95 Mlig455_020697, Mlig455_020766

Neo: -

Age: -

Region-enriched R4: 1.175/0.00014

FGFR1OP2 0.95 - - - 0.950 - -

Mlig455_020697 {REF} {Length: 1466} {TRANSSPLICED} {Pfam: SIKE family [PF05769.13, score=145.6]} {Human: ENSG00000111790, FGFR1OP2, FGFR1 oncogene partner 2, [RH, Score=116, Expect=4e-29]} {Mouse: ENSMUSG00000040242, Fgfr1op2, FGFR1 oncogene partner 2, [RH, Score=116, Expect=4e-29]} {Dmel: FBgn0031871, Fgop2, Fibroblast growth factor receptor 1 oncogene partner 2, [RH, Score=77.0, Expect=6e-15]} {Smed: dd_Smed_v6_3831_0_1, dd_Smed_v6_3831_0_1, [RH, Score=88.6, Expect=8e-19]} {RNA1509_34078, RNA1509_35738, RNA1509_50489} {RNA1310_24281, RNA1509_34078, RNA1509_35738, RNA1509_50489} {RNA1509_34078, RNA1509_35738, RNA1509_50489, RNA815_25316}

Mlig455_020766 {REF} {Length: 2958} {TRANSSPLICED} {Pfam: SIKE family [PF05769.13, score=145.6]} {Human: ENSG00000111790, FGFR1OP2, FGFR1 oncogene partner 2, [RH, Score=116, Expect=4e-29]} {Mouse: ENSMUSG00000040242, Fgfr1op2, FGFR1 oncogene partner 2, [RH, Score=116, Expect=4e-29]} {Dmel: FBgn0031871, Fgop2, Fibroblast growth factor receptor 1 oncogene partner 2, [RH, Score=77.0, Expect=6e-15]} {Smed: dd_Smed_v6_3831_0_1, dd_Smed_v6_3831_0_1, [RH, Score=88.6, Expect=8e-19]} {RNA1509_34078} {RNA1310_24281} {RNA815_25316}
29. MligTC455_42336 189 3.95 Mlig455_026740

Neo: -

Age: Down-Up-Down

DTNA 0.95 - - - 0.950 - - Mlig455_026740 {REF} {Length: 3388} {TRANSSPLICED} {Pfam: EF hand [PF09068.13, score=47.3]; EF-hand [PF09069.13, score=43.8]; Zinc finger, ZZ type [PF00569.19, score=39.7]; C1 domain [PF03107.18, score=25.4]} {Human: ENSG00000134769, DTNA, dystrobrevin alpha, [RH, Score=246, Expect=6e-72]} {Mouse: ENSMUSG00000024302, Dtna, dystrobrevin alpha, [RH, Score=244, Expect=1e-71]} {Dmel: FBgn0033739, Dyb, Dystrobrevin, [RH, Score=199, Expect=3e-54]} {Celegans: WBGene00001115, dyb-1, Dystrobrevin-1, [RH, Score=177, Expect=2e-47]} {Smed: dd_Smed_v6_12275_0_1, dd_Smed_v6_12275_0_1, [RH, Score=275, Expect=1e-79]} {RNA1509_17518} {RNA1310_10732.1} {RNA815_3713}
30. MligTC455_50488 347 7.22 Mlig455_026193

Neo: -

Age: -

INPP1 0.95 - - - 0.950 - - Mlig455_026193 {REF} {Length: 2896} {Pfam: Inositol monophosphatase family [PF00459.27, score=111.3]} {Human: ENSG00000151689, INPP1, inositol polyphosphate-1-phosphatase, [RH, Score=262, Expect=8e-84]} {Mouse: ENSMUSG00000026102, Inpp1, inositol polyphosphate-1-phosphatase, [RH, Score=294, Expect=1e-96]} {Dmel: FBgn0016672, Ipp, Inositol polyphosphate 1-phosphatase, [RH, Score=241, Expect=2e-76]} {Celegans: WBGene00044063, bpnt-1, 3'(2'), 5'-BisPhosphate NucleoTidase 1 homolog, [Score=75.1, Expect=6e-15]} {Smed: dd_Smed_v6_9612_0_1, dd_Smed_v6_9612_0_1, [RH, Score=189, Expect=2e-56]} {RNA1509_17015} {RNA1310_9873, RNA1509_17015} {RNA1509_17015, RNA815_6008}

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