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Results for MligTC455_40998

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_40998 202 4.21 Mlig455_030227, Mlig455_068004

Neo: -

Age: Down-Up-Up

PRG4

Mlig455_030227 {REF} {Length: 1061} {Mouse: ENSMUSG00000050675, Gp1ba, glycoprotein 1b, alpha polypeptide, [Score=63.9, Expect=8e-11]} {RNA1310_70482}

Mlig455_068004 {REF} {Length: 1488} {Human: ENSG00000116690, PRG4, proteoglycan 4, [RH, Score=55.1, Expect=2e-07]} {Mouse: ENSMUSG00000050675, Gp1ba, glycoprotein 1b, alpha polypeptide, [RH, Score=70.5, Expect=1e-12]} {Dmel: FBgn0052656, Muc11A, Mucin 11A, [Score=56.2, Expect=3e-08]} {RNA1310_70482}

Cumulative graph for MligTC455_40998

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -5.637 1.927 0.21631 0.85705
RegionR2 1.1 1.927 0.42029 0.81199
RegionR3 0.399 1.927 0.71593 1.00000
RegionR4 0.725 1.927 0.55223 0.87261
RegionR5 1.07 1.927 0.35411 0.70449
RegionR6 0.579 1.927 0.64235 1.00000
RegionR7 1.545 1.927 0.23085 0.85429
RegionR8 0.221 1.927 0.82038 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 5.6 1.927 0.26418 0.96957
RegenerationR2 0.542 1.927 0.58901 0.91074
RegenerationR3 -0.932 1.927 0.43927 0.82678
RegenerationR4 -0.482 1.927 0.64668 0.93150
RegenerationR5 -1.598 1.927 0.13985 0.55240
RegenerationR6 -0.662 1.927 0.60483 0.87097
RegenerationBL 1.156 1.927 0.26774 0.62685
RegenerationTP 1.275 1.927 0.28868 0.73421


Genes with expression patterns similar to MligTC455_40998

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_40998 202 4.21 Mlig455_030227, Mlig455_068004

Neo: -

Age: Down-Up-Up

PRG4 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_030227 {REF} {Length: 1061} {Mouse: ENSMUSG00000050675, Gp1ba, glycoprotein 1b, alpha polypeptide, [Score=63.9, Expect=8e-11]} {RNA1310_70482}

Mlig455_068004 {REF} {Length: 1488} {Human: ENSG00000116690, PRG4, proteoglycan 4, [RH, Score=55.1, Expect=2e-07]} {Mouse: ENSMUSG00000050675, Gp1ba, glycoprotein 1b, alpha polypeptide, [RH, Score=70.5, Expect=1e-12]} {Dmel: FBgn0052656, Muc11A, Mucin 11A, [Score=56.2, Expect=3e-08]} {RNA1310_70482}
2. MligTC455_12731 331 6.89 Mlig455_005108

Neo: -

Age: -

Region-enriched R6: 3.150/0.01756

2.736 0.888 - - 0.990 - 0.858 Mlig455_005108 {REF} {Length: 654} {NoTransDecoderORF} {RNA1509_44841} {RNA1310_66981} {RNA815_54535}
3. MligTC455_43329 235 4.9 Mlig455_007154

Neo: -

Age: -

Region-enriched R2: 3.268/0.02528
Region-enriched R5: 2.289/0.03532

SMURF2 2.678 0.966 - - 0.987 - 0.725 Mlig455_007154 {REF} {Length: 4687} {Pfam: HECT-domain (ubiquitin-transferase) [PF00632.27, score=303.1]; WW domain [PF00397.28, score=64.2]} {Human: ENSG00000108854, SMURF2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=636, Expect=0.0]} {Mouse: ENSMUSG00000018363, Smurf2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=637, Expect=0.0]} {Dmel: FBgn0259174, Nedd4, [Score=409, Expect=4e-133]} {Celegans: WBGene00022358, Y92H12A.2, E3 ubiquitin-protein ligase, [Score=400, Expect=2e-133]} {Smed: dd_Smed_v6_7322_0_1, dd_Smed_v6_7322_0_1, [Score=398, Expect=2e-128]} {RNA1509_42014} {RNA1310_6371} {RNA815_17584}
4. MligTC455_28148 364 7.58 Mlig455_012154, Mlig455_016372, Mlig455_031967

Neo: -

Age: Up-Up-Down

Regeneration-enriched R6: 3.876
Regeneration-enriched BL: 2.501

2.5 - - - 0.966 0.799 0.735

Mlig455_012154 {REF} {Length: 2493} {NoTransDecoderORF} {RNA1509_13222} {RNA1310_34828.2} {RNA815_11419.1}

Mlig455_016372 {REF} {Length: 2012} {NoTransDecoderORF} {RNA1509_25657} {RNA1310_77645} {RNA815_34613}

Mlig455_031967 {REF} {Length: 3036} {NoTransDecoderORF} {RNA1509_53435} {RNA1310_34828.2} {RNA815_11419.1}
5. MligTC455_20542 5447 113.47 Mlig455_003023, Mlig455_003318

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.611

Region-enriched R8: 1.173/0.00545

KY 2.466 0.789 - - 0.957 0.720 -

Mlig455_003023 {REF} {Length: 19522} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=22.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=79.7, Expect=1e-13]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=77.8, Expect=3e-13]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=103, Expect=4e-21]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=90.5, Expect=2e-17]} {Smed: dd_Smed_v6_1109_0_1, dd_Smed_v6_1109_0_1, [Score=290, Expect=4e-80]} {RNA1509_704} {RNA1310_3180} {RNA815_1159.1}

Mlig455_003318 {REF} {Length: 19222} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=22.9]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=80.5, Expect=7e-14]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=75.5, Expect=2e-12]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=99.8, Expect=5e-20]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=90.9, Expect=1e-17]} {Smed: dd_Smed_v6_1109_0_1, dd_Smed_v6_1109_0_1, [Score=292, Expect=8e-81]} {RNA1509_2987, RNA1509_37803, RNA1509_704} {RNA1310_3180, RNA1509_2987, RNA1509_37803} {RNA1509_2987, RNA1509_37803, RNA815_1159.1}
6. MligTC455_23031 559 11.65 Mlig455_004920, Mlig455_019740

Neo: -

Age: logFC(26M/2M)=0.748

NLK 2.419 - 0.726 - 0.981 - 0.712

Mlig455_004920 {REF} {Length: 2917} {Pfam: Protein kinase domain [PF00069.27, score=199.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=99.1]; Phosphotransferase enzyme family [PF01636.25, score=23.6]; Fungal protein kinase [PF17667.3, score=21.1]; ABC1 atypical kinase-like domain [PF03109.18, score=18.6]} {Human: ENSG00000087095, NLK, nemo like kinase, [Score=380, Expect=2e-126]} {Mouse: ENSMUSG00000017376, Nlk, nemo like kinase, [Score=380, Expect=1e-126]} {Dmel: FBgn0011817, nmo, nemo, [Score=369, Expect=7e-124]} {Celegans: WBGene00003048, lit-1, Serine/threonine kinase NLK, [Score=347, Expect=4e-115]} {Smed: dd_Smed_v6_4172_0_3, dd_Smed_v6_4172_0_3, [Score=350, Expect=3e-116]} {RNA1310_28916} {RNA815_34936}

Mlig455_019740 {REF} {Length: 3316} {Pfam: Protein kinase domain [PF00069.27, score=199.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=99.1]; Phosphotransferase enzyme family [PF01636.25, score=22.2]; Fungal protein kinase [PF17667.3, score=21.2]; ABC1 atypical kinase-like domain [PF03109.18, score=18.6]} {Human: ENSG00000087095, NLK, nemo like kinase, [Score=367, Expect=9e-122]} {Mouse: ENSMUSG00000017376, Nlk, nemo like kinase, [Score=367, Expect=7e-122]} {Dmel: FBgn0011817, nmo, nemo, [Score=364, Expect=2e-122]} {Celegans: WBGene00003048, lit-1, Serine/threonine kinase NLK, [Score=344, Expect=3e-114]} {Smed: dd_Smed_v6_4172_0_3, dd_Smed_v6_4172_0_3, [Score=351, Expect=8e-117]} {RNA1310_28916} {RNA815_34936}
7. MligTC455_41155 175 3.64 Mlig455_044206

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.465

GLIPR2 2.398 0.985 - - - 0.702 0.711 Mlig455_044206 {REF} {Length: 2200} {Pfam: Cysteine-rich secretory protein family [PF00188.28, score=135.8]} {Human: ENSG00000122694, GLIPR2, GLI pathogenesis related 2, [RH, Score=123, Expect=9e-33]} {Mouse: ENSMUSG00000028480, Glipr2, GLI pathogenesis-related 2, [RH, Score=134, Expect=8e-37]} {Dmel: FBgn0031407, CG4270, [Score=99.0, Expect=5e-24]} {Celegans: WBGene00017055, D2062.1, [RH, Score=78.6, Expect=1e-16]} {Smed: dd_Smed_v6_12963_0_1, dd_Smed_v6_12963_0_1, [RH, Score=168, Expect=5e-47]} {RNA1509_23598} {RNA1310_13477} {RNA815_15619}
8. MligTC455_26666 497 10.35 Mlig455_014576

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.303

CNBD2 1.972 0.988 - - 0.984 - - Mlig455_014576 {REF} {Length: 3147} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=74.1]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [RH, Score=97.8, Expect=2e-20]} {Mouse: ENSMUSG00000038085, Cnbd2, cyclic nucleotide binding domain containing 2, [RH, Score=86.3, Expect=3e-17]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [Score=58.2, Expect=9e-09]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=62.0, Expect=5e-10]} {Smed: dd_Smed_v6_15589_0_1, dd_Smed_v6_15589_0_1, [RH, Score=451, Expect=2e-148]} {RNA1509_14495, RNA1509_43806} {RNA1310_6298, RNA1509_43806} {RNA1509_43806, RNA815_2010}
9. MligTC455_44648 177 3.69 Mlig455_013655

Neo: -

Age: -

1.966 0.985 - - 0.981 - - Mlig455_013655 {REF} {Length: 2045} {Pfam: Protein kinase domain [PF00069.27, score=24.6]} {RNA1509_54731} {RNA1310_1875.2} {RNA815_820}
10. MligTC455_41222 503 10.48 Mlig455_008819, Mlig455_008917

Neo: Int S/G2/M

Age: Down-Up-Up

Region-enriched R5: 2.661/0.00033

UBE2T 1.953 0.987 - - 0.966 - -

Mlig455_008819 {REF} {Length: 1153} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=127.8]} {Human: ENSG00000077152, UBE2T, ubiquitin conjugating enzyme E2 T, [RH, Score=166, Expect=2e-51]} {Mouse: ENSMUSG00000026429, Ube2t, ubiquitin-conjugating enzyme E2T, [RH, Score=149, Expect=4e-45]} {Dmel: FBgn0000173, ben, bendless, [Score=129, Expect=4e-38]} {Celegans: WBGene00006708, ubc-13, Ubiquitin-conjugating enzyme E2 13, [Score=134, Expect=7e-40]} {Smed: dd_Smed_v6_1075_0_1, dd_Smed_v6_1075_0_1, [Score=130, Expect=1e-38]} {RNA1509_29240} {RNA1310_31665} {RNA815_39037}

Mlig455_008917 {REF} {Length: 1154} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=127.8]} {Human: ENSG00000077152, UBE2T, ubiquitin conjugating enzyme E2 T, [RH, Score=166, Expect=2e-51]} {Mouse: ENSMUSG00000026429, Ube2t, ubiquitin-conjugating enzyme E2T, [RH, Score=149, Expect=4e-45]} {Dmel: FBgn0000173, ben, bendless, [Score=129, Expect=4e-38]} {Celegans: WBGene00006708, ubc-13, Ubiquitin-conjugating enzyme E2 13, [Score=134, Expect=7e-40]} {Smed: dd_Smed_v6_1075_0_1, dd_Smed_v6_1075_0_1, [Score=130, Expect=1e-38]} {RNA1509_29240} {RNA1310_31665} {RNA815_39037}
11. MligTC455_44341 241 5.03 Mlig455_004553

Neo: -

Age: -

SENP8 1.93 0.955 - - 0.975 - - Mlig455_004553 {REF} {Length: 1090} {Pfam: Ulp1 protease family, C-terminal catalytic domain [PF02902.21, score=31.5]} {Human: ENSG00000166192, SENP8, SUMO peptidase family member, NEDD8 specific, [Score=50.1, Expect=3e-07]} {Mouse: ENSMUSG00000051705, Senp8, SUMO/sentrin specific peptidase 8, [Score=47.4, Expect=2e-06]} {RNA1509_41235} {RNA1310_35410} {RNA815_32992}
12. MligTC455_29193 967 20.15 Mlig455_018315, Mlig455_061014, Mlig455_067207

Neo: -

Age: Down-Down-Up

1.915 0.954 - - 0.961 - -

Mlig455_018315 {REF} {Length: 2676} {TRANSSPLICED} {RNA1509_52931} {RNA1310_28021} {RNA815_28552}

Mlig455_061014 {REF} {Length: 2001} {RNA1310_29654.1} {RNA815_17301.1}

Mlig455_067207 {REF} {Length: 584} {TRANSSPLICED} {RNA1310_29654.1} {RNA815_17301.1}
13. MligTC455_43031 730 15.2 Mlig455_048533

Neo: -

Age: Down-Up-Down

ESRRG 1.907 0.987 - - 0.920 - - Mlig455_048533 {REF} {Length: 4806} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=95.0]; Zinc finger, C4 type (two domains) [PF00105.20, score=65.1]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=31.3]; Serpentine type 7TM GPCR chemoreceptor Srv [PF10323.11, score=27.1]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=24.4]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=23.0]} {Human: ENSG00000196482, ESRRG, estrogen related receptor gamma, [Score=114, Expect=3e-26]; ENSG00000119715, ESRRB, estrogen related receptor beta, [Score=112, Expect=9e-26]; ENSG00000173153, ESRRA, estrogen related receptor alpha, [Score=110, Expect=4e-25]} {Mouse: ENSMUSG00000021255, Esrrb, estrogen related receptor, beta, [Score=115, Expect=8e-27]; ENSMUSG00000026610, Esrrg, estrogen-related receptor gamma, [Score=113, Expect=3e-26]} {Dmel: FBgn0035849, ERR, estrogen-related receptor, [Score=104, Expect=3e-23]} {Celegans: WBGene00003628, nhr-35, Nuclear hormone receptor family member nhr-35, [Score=85.9, Expect=3e-17]} {Smed: dd_Smed_v6_12699_0_1, dd_Smed_v6_12699_0_1, [Score=93.6, Expect=1e-19]} {RNA1509_22064} {RNA1310_27500, RNA1509_22064} {RNA1509_22064, RNA815_8823}
14. MligTC455_47601 126 2.62 Mlig455_056477

Neo: -

Age: Up-Down-Up

NRXN1 1.897 - - - 0.972 - 0.925 Mlig455_056477 {REF} {Length: 3481} {Pfam: Laminin G domain [PF02210.26, score=58.3]; Laminin G domain [PF00054.25, score=43.2]; Syndecan domain [PF01034.22, score=27.4]} {Human: ENSG00000179915, NRXN1, neurexin 1, [Score=142, Expect=4e-35]} {Mouse: ENSMUSG00000024109, Nrxn1, neurexin I, [Score=142, Expect=1e-35]} {Dmel: FBgn0038975, Nrx-1, Neurexin 1, [Score=102, Expect=2e-22]} {Smed: dd_Smed_v6_13697_0_1, dd_Smed_v6_13697_0_1, [Score=142, Expect=8e-36]} {RNA1509_55888} {RNA1310_37025, RNA1509_55888} {RNA1509_55888, RNA815_22404}
15. MligTC455_16902 287 5.97 Mlig455_030566

Neo: -

Age: -

NETO2 1.895 0.924 - - 0.971 - - Mlig455_030566 {REF} {Length: 3702} {Pfam: CUB domain [PF00431.22, score=70.2]; Low-density lipoprotein receptor domain class A [PF00057.20, score=34.0]} {Human: ENSG00000171208, NETO2, neuropilin and tolloid like 2, [Score=130, Expect=3e-31]} {Mouse: ENSMUSG00000036902, Neto2, neuropilin (NRP) and tolloid (TLL)-like 2, [Score=129, Expect=5e-31]} {Dmel: FBgn0265416, Neto, Neuropilin and tolloid-like, [Score=118, Expect=5e-27]} {Celegans: WBGene00019360, neto-1, NETO (NEuropilin and TOlloid-like) homolog, [RH, Score=125, Expect=4e-31]} {Smed: dd_Smed_v6_8579_0_1, dd_Smed_v6_8579_0_1, [RH, Score=143, Expect=2e-35]} {RNA1509_23788, RNA1509_52170} {RNA1310_3313, RNA1509_23788, RNA1509_52170} {RNA1509_23788, RNA1509_52170, RNA815_7210}
16. MligTC455_19737 936 19.49 Mlig455_001707

Neo: -

Age: -

1.89 0.900 - - 0.990 - - Mlig455_001707 {REF} {Length: 1748} {TRANSSPLICED} {Pfam: Mucin-like [PF16058.7, score=34.2]} {Smed: dd_Smed_v6_3936_0_1, dd_Smed_v6_3936_0_1, [Score=102, Expect=4e-24]} {RNA1509_50300} {RNA1310_14121} {RNA815_5699.1}
17. MligTC455_16991 437 9.09 Mlig455_057989

Neo: -

Age: Up-Up-Down

Regeneration-downregulated BL: -7.705

Regeneration-depleted BL: -7.705

1.888 0.908 - - 0.980 - - Mlig455_057989 {REF} {Length: 4840} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=124.1]; WSC domain [PF01822.21, score=40.4]} {Celegans: WBGene00003168, mec-4, Degenerin mec-4, [Score=64.3, Expect=3e-10]} {Smed: dd_Smed_v6_15195_0_1, dd_Smed_v6_15195_0_1, [Score=65.1, Expect=1e-10]} {RNA1509_20328} {RNA1310_3478} {RNA815_19382.2}
18. MligTC455_00831 642 13.37 Mlig455_016457, Mlig455_016523

Neo: -

Age: logFC(26M/2M)=0.506

LGR5 1.886 0.910 - - 0.976 - -

Mlig455_016457 {REF} {Length: 4347} {Pfam: Leucine rich repeat [PF13855.8, score=86.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=45.8]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=40.5]} {Human: ENSG00000139292, LGR5, leucine rich repeat containing G protein-coupled receptor 5, [Score=58.5, Expect=7e-08]; ENSG00000145147, SLIT2, slit guidance ligand 2, [Score=57.0, Expect=2e-07]} {Mouse: ENSMUSG00000020140, Lgr5, leucine rich repeat containing G protein coupled receptor 5, [Score=59.7, Expect=2e-08]} {Dmel: FBgn0267435, chp, chaoptin, [Score=67.0, Expect=8e-11]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=55.8, Expect=2e-07]} {RNA1509_8817} {RNA1310_2409} {RNA815_590.1}

Mlig455_016523 {REF} {Length: 3360} {Pfam: Leucine rich repeat [PF13855.8, score=41.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=39.1]} {RNA1509_8817} {RNA1310_22547} {RNA815_590.1}
19. MligTC455_12732 248 5.17 Mlig455_005195

Neo: -

Age: -

RAB13 1.881 - - - 0.982 - 0.899 Mlig455_005195 {REF} {Length: 2008} {Pfam: Ras family [PF00071.24, score=176.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=103.0]; ADP-ribosylation factor family [PF00025.23, score=63.3]; 50S ribosome-binding GTPase [PF01926.25, score=25.9]; Gtr1/RagA G protein conserved region [PF04670.14, score=19.7]; RsgA GTPase [PF03193.18, score=18.6]} {Human: ENSG00000143545, RAB13, RAB13, member RAS oncogene family, [Score=170, Expect=4e-52]; ENSG00000285641, AL358472.6, novel protein, [Score=170, Expect=4e-52]; ENSG00000174903, RAB1B, RAB1B, member RAS oncogene family, [Score=168, Expect=1e-51]; ENSG00000139998, RAB15, RAB15, member RAS oncogene family, [Score=168, Expect=3e-51]; ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=167, Expect=3e-51]; ENSG00000138069, RAB1A, RAB1A, member RAS oncogene family, [Score=167, Expect=4e-51]; ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [Score=166, Expect=1e-50]; ENSG00000137502, RAB30, RAB30, member RAS oncogene family, [Score=166, Expect=2e-50]; ENSG00000084733, RAB10, RAB10, member RAS oncogene family, [Score=165, Expect=3e-50]} {Mouse: ENSMUSG00000027935, Rab13, RAB13, member RAS oncogene family, [Score=172, Expect=4e-53]; ENSMUSG00000021062, Rab15, RAB15, member RAS oncogene family, [Score=168, Expect=1e-51]; ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=168, Expect=1e-51]; ENSMUSG00000024870, Rab1b, RAB1B, member RAS oncogene family, [Score=167, Expect=3e-51]; ENSMUSG00000020149, Rab1a, RAB1A, member RAS oncogene family, [Score=167, Expect=3e-51]; ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [Score=166, Expect=8e-51]; ENSMUSG00000030643, Rab30, RAB30, member RAS oncogene family, [Score=166, Expect=1e-50]; ENSMUSG00000020671, Rab10, RAB10, member RAS oncogene family, [Score=165, Expect=2e-50]} {Dmel: FBgn0285937, Rab1, [Score=172, Expect=3e-53]} {Celegans: WBGene00004266, rab-1, RAB family, [Score=180, Expect=2e-56]} {Smed: dd_Smed_v6_854_0_8, dd_Smed_v6_854_0_8, [Score=175, Expect=1e-54]} {RNA1509_20337, RNA1509_44841} {RNA1310_45399, RNA1509_44841} {RNA1509_44841, RNA815_21941}
20. MligTC455_24052 272 5.66 Mlig455_065284, Mlig455_065290

Neo: -

Age: Down-Up-Down

1.877 - - - 0.985 0.892 -

Mlig455_065284 {REF} {Length: 1698} {RNA1509_34738} {RNA1310_59354} {RNA815_53074}

Mlig455_065290 {REF} {Length: 3344} {TRANSSPLICED} {Pfam: EamA-like transporter family [PF00892.22, score=24.1]} {RNA1509_34738} {RNA1310_59354} {RNA815_26334}
21. MligTC455_53738 469 9.77 Mlig455_038341, Mlig455_038349, Mlig455_038367, Mlig455_068286

Neo: -

Age: -

1.875 - - - 0.983 - 0.892

Mlig455_038341 {REF} {Length: 672} {RNA1310_69225} {RNA815_63432}

Mlig455_038349 {REF} {Length: 697} {RNA1310_69225} {RNA815_63432}

Mlig455_038367 {REF} {Length: 1012} {RNA1310_69225} {RNA815_63432}

Mlig455_068286 {REF} {Length: 1010} {RNA1310_69225} {RNA815_63432}
22. MligTC455_16863 349 7.26 Mlig455_009275

Neo: -

Age: Down-Up-Down

DYRK1B 1.865 0.882 - - 0.983 - - Mlig455_009275 {REF} {Length: 5761} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=162.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=82.6]} {Human: ENSG00000281320, DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B, [Score=479, Expect=9e-163]; ENSG00000105204, DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B, [Score=479, Expect=9e-163]; ENSG00000157540, DYRK1A, dual specificity tyrosine phosphorylation regulated kinase 1A, [Score=469, Expect=1e-157]} {Mouse: ENSMUSG00000002409, Dyrk1b, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b, [Score=480, Expect=3e-162]; ENSMUSG00000022897, Dyrk1a, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a, [Score=470, Expect=5e-158]} {Dmel: FBgn0259168, mnb, minibrain, [Score=495, Expect=1e-169]} {Celegans: WBGene00003149, mbk-1, Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1, [Score=431, Expect=3e-141]} {Smed: dd_Smed_v6_3773_0_1, dd_Smed_v6_3773_0_1, [Score=425, Expect=3e-136]} {RNA1509_9464} {RNA1310_10341} {RNA815_7238.1}
23. MligTC455_30458 451 9.39 Mlig455_062993

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.026

FTCD 1.859 0.895 - - 0.964 - - Mlig455_062993 {REF} {Length: 2008} {Pfam: Formiminotransferase domain, N-terminal subdomain [PF07837.14, score=187.7]; Formiminotransferase domain [PF02971.16, score=179.9]; Formiminotransferase-cyclodeaminase [PF04961.14, score=66.0]} {Human: ENSG00000160282, FTCD, formimidoyltransferase cyclodeaminase, [Score=400, Expect=9e-135]; ENSG00000281775, FTCD, formimidoyltransferase cyclodeaminase, [Score=399, Expect=6e-136]} {Mouse: ENSMUSG00000001155, Ftcd, formiminotransferase cyclodeaminase, [Score=402, Expect=7e-136]} {Smed: dd_Smed_v6_7815_0_1, dd_Smed_v6_7815_0_1, [Score=292, Expect=3e-93]} {RNA1509_29292} {RNA1310_13312} {RNA815_5334}
24. MligTC455_17539 396 8.24 Mlig455_020650

Neo: -

Age: logFC(26M/2M)=-0.311

RPGRIP1L 1.858 0.865 - - 0.993 - - Mlig455_020650 {REF} {Length: 4523} {TRANSSPLICED} {Pfam: First C2 domain of RPGR-interacting protein 1 [PF11618.10, score=156.0]; Retinitis pigmentosa G-protein regulator interacting C-terminal [PF18111.3, score=63.1]; C2 domain [PF00168.32, score=39.2]} {Human: ENSG00000103494, RPGRIP1L, RPGRIP1 like, [RH, Score=486, Expect=3e-150]} {Mouse: ENSMUSG00000033282, Rpgrip1l, Rpgrip1-like, [Score=448, Expect=3e-136]} {Smed: dd_Smed_v6_11425_0_1, dd_Smed_v6_11425_0_1, [RH, Score=489, Expect=2e-151]} {RNA1509_17201, RNA1509_3677, RNA1509_51934} {RNA1310_2541.1, RNA1509_17201, RNA1509_3677, RNA1509_51934} {RNA1509_17201, RNA1509_3677, RNA1509_51934, RNA815_452}
25. MligTC455_37160 1139 23.73 Mlig455_015317, Mlig455_032998, Mlig455_068744

Neo: -

Age: logFC(26M/2M)=-0.355

Region-enriched R2: 1.560/0.01222

TTC28 1.855 0.881 - - 0.974 - -

Mlig455_015317 {REF} {Length: 5958} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=63.4]; Tetratricopeptide repeat [PF07719.19, score=51.3]; Tetratricopeptide repeat [PF00515.30, score=40.4]; Tetratricopeptide repeat [PF13181.8, score=39.5]; CHAT domain [PF12770.9, score=37.9]; Tetratricopeptide repeat [PF14559.8, score=23.5]; Tetratricopeptide repeat [PF13431.8, score=22.4]; Tetratricopeptide repeat [PF13176.8, score=20.4]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=69.3, Expect=7e-11]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=70.9, Expect=2e-11]} {RNA1509_5411} {RNA1310_761.1} {RNA815_600}

Mlig455_032998 {REF} {Length: 5728} {Pfam: CHAT domain [PF12770.9, score=39.2]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=67.8, Expect=1e-10]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=69.3, Expect=3e-11]} {RNA1509_5411} {RNA1310_761.1} {RNA815_600}

Mlig455_068744 {REF} {Length: 5980} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=62.6]; Tetratricopeptide repeat [PF07719.19, score=49.0]; Tetratricopeptide repeat [PF13181.8, score=39.3]; Tetratricopeptide repeat [PF00515.30, score=38.4]; CHAT domain [PF12770.9, score=37.8]; Tetratricopeptide repeat [PF14559.8, score=22.1]; Tetratricopeptide repeat [PF13431.8, score=20.8]; Tetratricopeptide repeat [PF13176.8, score=19.2]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=66.2, Expect=6e-10]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=67.8, Expect=1e-10]} {RNA1509_5411} {RNA1310_761.2} {RNA815_600}
26. MligTC455_48927 803 16.73 Mlig455_054812

Neo: -

Age: Down-Up-Up

1.855 0.974 - - 0.881 - - Mlig455_054812 {REF} {Length: 627} {Pfam: Pancreatic hormone peptide [PF00159.20, score=68.1]; Glutaredoxin 2, C terminal domain [PF04399.15, score=21.5]} {Smed: dd_Smed_v6_16946_0_1, dd_Smed_v6_16946_0_1, [RH, Score=42.4, Expect=4e-06]} {RNA1509_56617} {RNA1310_62193} {RNA815_34296.1}
27. MligTC455_48785 525 10.94 Mlig455_045165

Neo: -

Age: -

DCAF7 1.846 0.884 - - 0.962 - - Mlig455_045165 {REF} {Length: 2087} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=26.2]} {Human: ENSG00000136485, DCAF7, DDB1 and CUL4 associated factor 7, [RH, Score=600, Expect=0.0]} {Mouse: ENSMUSG00000049354, Dcaf7, DDB1 and CUL4 associated factor 7, [RH, Score=600, Expect=0.0]} {Dmel: FBgn0266848, wap, wings apart, [RH, Score=577, Expect=0.0]} {Celegans: WBGene00009976, swan-2, Seven WD repeats, AN11 family, [RH, Score=471, Expect=1e-165]} {Smed: dd_Smed_v6_3579_0_1, dd_Smed_v6_3579_0_1, [RH, Score=552, Expect=0.0]} {RNA1509_38686} {RNA1310_14635, RNA1509_38686} {RNA1509_38686, RNA815_37344}
28. MligTC455_30457 489 10.18 Mlig455_051232

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.520

FTCD 1.842 0.880 - - 0.962 - - Mlig455_051232 {REF} {Length: 3312} {Pfam: Formiminotransferase domain, N-terminal subdomain [PF07837.14, score=229.8]; Formiminotransferase domain [PF02971.16, score=200.9]; Formiminotransferase-cyclodeaminase [PF04961.14, score=176.4]; SAP domain [PF02037.29, score=32.2]} {Human: ENSG00000160282, FTCD, formimidoyltransferase cyclodeaminase, [RH, Score=571, Expect=0.0]} {Mouse: ENSMUSG00000001155, Ftcd, formiminotransferase cyclodeaminase, [RH, Score=571, Expect=0.0]} {Smed: dd_Smed_v6_7815_0_1, dd_Smed_v6_7815_0_1, [RH, Score=398, Expect=1e-127]} {RNA1509_29292} {RNA1310_13312} {RNA815_5334}
29. MligTC455_32020 241 5.03 Mlig455_009658, Mlig455_046589

Neo: -

Age: -

1.84 0.965 - - 0.875 - -

Mlig455_009658 {REF} {Length: 6094} {RNA1509_2515} {RNA1310_5479.1} {RNA815_1043.1}

Mlig455_046589 {REF} {Length: 1092} {NoTransDecoderORF} {RNA1509_2515} {RNA1310_23566} {RNA815_3258.1}
30. MligTC455_50793 1150 23.96 Mlig455_050628

Neo: -

Age: -

1.837 0.881 - - 0.956 - - Mlig455_050628 {REF} {Length: 1302} {TRANSSPLICED} {RNA1509_14468, RNA1509_9990} {RNA1310_27653, RNA1509_14468, RNA1509_9990} {RNA1509_14468, RNA1509_9990, RNA815_14056}
31. MligTC455_23567 109 2.27 Mlig455_013185

Neo: -

Age: Down-Up-Down

BCHE 1.835 0.979 - - - - 0.856 Mlig455_013185 {REF} {Length: 4455} {Pfam: Carboxylesterase family [PF00135.30, score=432.1]; alpha/beta hydrolase fold [PF07859.15, score=35.5]} {Human: ENSG00000114200, BCHE, butyrylcholinesterase, [Score=317, Expect=9e-99]; ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=312, Expect=2e-96]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [Score=324, Expect=3e-101]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=249, Expect=8e-73]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=327, Expect=2e-102]} {Smed: dd_Smed_v6_15930_0_1, dd_Smed_v6_15930_0_1, [RH, Score=412, Expect=4e-134]} {RNA1509_26775} {RNA1310_8383.1} {RNA815_10983}
32. MligTC455_15642 144 3 Mlig455_013852

Neo: -

Age: -

CLSTN2 1.829 0.993 - - - - 0.836 Mlig455_013852 {REF} {Length: 4455} {Pfam: Calsyntenin C-terminal [PF19699.1, score=44.6]; Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=27.1]; Cadherin domain [PF00028.19, score=23.0]} {Human: ENSG00000158258, CLSTN2, calsyntenin 2, [RH, Score=236, Expect=1e-63]} {Mouse: ENSMUSG00000032452, Clstn2, calsyntenin 2, [Score=230, Expect=5e-62]} {Dmel: FBgn0039928, Cals, Calsyntenin-1, [Score=193, Expect=4e-50]} {Celegans: WBGene00000403, casy-1, CAlSYntenin/Alcadein homolog; Calsyntenin, [RH, Score=228, Expect=1e-61]} {Smed: dd_Smed_v6_3122_0_1, dd_Smed_v6_3122_0_1, [RH, Score=283, Expect=1e-79]} {RNA1509_2809} {RNA1310_1704} {RNA815_625}
33. MligTC455_50228 1128 23.5 Mlig455_016788, Mlig455_016809

Neo: -

Age: -

RAB5B 1.827 0.850 - - 0.977 - -

Mlig455_016788 {REF} {Length: 1792} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=200.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=122.1]; ADP-ribosylation factor family [PF00025.23, score=50.5]; 50S ribosome-binding GTPase [PF01926.25, score=25.7]; Gtr1/RagA G protein conserved region [PF04670.14, score=22.8]; RsgA GTPase [PF03193.18, score=19.5]} {Human: ENSG00000111540, RAB5B, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=1e-96]; ENSG00000108774, RAB5C, RAB5C, member RAS oncogene family, [RH, Score=278, Expect=6e-95]; ENSG00000144566, RAB5A, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=4e-94]} {Mouse: ENSMUSG00000000711, Rab5b, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=7e-97]; ENSMUSG00000019173, Rab5c, RAB5C, member RAS oncogene family, [RH, Score=277, Expect=2e-95]; ENSMUSG00000017831, Rab5a, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=2e-94]} {Dmel: FBgn0014010, Rab5, [RH, Score=275, Expect=2e-94]} {Celegans: WBGene00004268, rab-5, RAB family, [RH, Score=275, Expect=8e-95]} {Smed: dd_Smed_v6_796_0_1, dd_Smed_v6_796_0_1, [RH, Score=278, Expect=2e-96]} {RNA1509_2296, RNA1509_42263} {RNA1310_25305, RNA1509_42263} {RNA1509_42263, RNA815_10567}

Mlig455_016809 {REF} {Length: 1784} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=200.6]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=122.1]; ADP-ribosylation factor family [PF00025.23, score=50.5]; 50S ribosome-binding GTPase [PF01926.25, score=25.7]; Gtr1/RagA G protein conserved region [PF04670.14, score=22.8]; RsgA GTPase [PF03193.18, score=19.5]} {Human: ENSG00000111540, RAB5B, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=1e-96]; ENSG00000108774, RAB5C, RAB5C, member RAS oncogene family, [RH, Score=278, Expect=6e-95]; ENSG00000144566, RAB5A, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=4e-94]} {Mouse: ENSMUSG00000000711, Rab5b, RAB5B, member RAS oncogene family, [RH, Score=281, Expect=7e-97]; ENSMUSG00000019173, Rab5c, RAB5C, member RAS oncogene family, [RH, Score=277, Expect=2e-95]; ENSMUSG00000017831, Rab5a, RAB5A, member RAS oncogene family, [RH, Score=275, Expect=2e-94]} {Dmel: FBgn0014010, Rab5, [RH, Score=275, Expect=2e-94]} {Celegans: WBGene00004268, rab-5, RAB family, [RH, Score=275, Expect=8e-95]} {Smed: dd_Smed_v6_796_0_1, dd_Smed_v6_796_0_1, [RH, Score=278, Expect=2e-96]} {RNA1509_2296} {RNA1310_25305, RNA1509_2296} {RNA1509_2296, RNA815_10567}
34. MligTC455_36484 730 15.2 Mlig455_008622

Neo: -

Age: -

TAF5 1.812 0.846 - - 0.966 - - Mlig455_008622 {REF} {Length: 5592} {Pfam: WD domain, G-beta repeat [PF00400.34, score=123.9]; WD40 associated region in TFIID subunit, NTD2 domain [PF04494.17, score=90.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=41.2]; WD40 region of Ge1, enhancer of mRNA-decapping protein [PF16529.7, score=17.8]} {Human: ENSG00000148835, TAF5, TATA-box binding protein associated factor 5, [RH, Score=426, Expect=2e-138]} {Mouse: ENSMUSG00000025049, Taf5, TATA-box binding protein associated factor 5, [RH, Score=426, Expect=9e-139]} {Dmel: FBgn0010356, Taf5, TBP-associated factor 5, [RH, Score=380, Expect=2e-122]} {Celegans: WBGene00006386, taf-5, TAF (TBP-associated transcription factor) family, [RH, Score=254, Expect=3e-75]} {Smed: dd_Smed_v6_7319_0_1, dd_Smed_v6_7319_0_1, [RH, Score=311, Expect=2e-96]} {RNA1509_15120} {RNA1310_12001, RNA1509_15120} {RNA1509_15120, RNA815_9687}
35. MligTC455_52143 317 6.6 Mlig455_059304

Neo: -

Age: -

CETN3 1.809 - - - 0.951 0.858 - Mlig455_059304 {REF} {Length: 795} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=70.6]; EF hand [PF00036.34, score=61.4]; EF-hand domain pair [PF13833.8, score=60.8]; EF-hand domain [PF13405.8, score=49.6]; EF hand [PF13202.8, score=33.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=23.9]; EF-hand domain [PF17959.3, score=21.9]; Caleosin related protein [PF05042.15, score=19.1]} {Human: ENSG00000153140, CETN3, centrin 3, [Score=205, Expect=6e-68]} {Mouse: ENSMUSG00000021537, Cetn3, centrin 3, [Score=205, Expect=3e-68]} {Dmel: FBgn0040010, CG17493, [Score=123, Expect=7e-36]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=81.6, Expect=3e-20]} {Smed: dd_Smed_v6_11582_0_1, dd_Smed_v6_11582_0_1, [Score=181, Expect=3e-59]} {RNA1509_5944} {RNA1310_28289.1} {RNA815_14129}
36. MligTC455_44647 489 10.19 Mlig455_006279

Neo: -

Age: -

OXSR1 1.806 0.970 - - 0.836 - - Mlig455_006279 {REF} {Length: 2340} {Pfam: Protein kinase domain [PF00069.27, score=128.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=97.0]; Phosphotransferase enzyme family [PF01636.25, score=18.9]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=18.9]; Fungal protein kinase [PF17667.3, score=18.8]} {Human: ENSG00000172939, OXSR1, oxidative stress responsive 1, [Score=89.7, Expect=2e-18]; ENSG00000091436, MAP3K20, mitogen-activated protein kinase kinase kinase 20, [Score=87.0, Expect=1e-17]; ENSG00000135341, MAP3K7, mitogen-activated protein kinase kinase kinase 7, [Score=85.5, Expect=4e-17]} {Mouse: ENSMUSG00000036737, Oxsr1, oxidative-stress responsive 1, [Score=89.7, Expect=1e-18]; ENSMUSG00000028284, Map3k7, mitogen-activated protein kinase kinase kinase 7, [Score=85.5, Expect=3e-17]} {Dmel: FBgn0046689, Takl1, Tak1-like 1, [Score=86.7, Expect=4e-18]} {Celegans: WBGene00006971, zak-1, Mammalian ZAK kinase homolog, [Score=82.0, Expect=3e-16]} {Smed: dd_Smed_v6_2589_0_2, dd_Smed_v6_2589_0_2, [Score=100, Expect=1e-22]} {RNA1509_40362, RNA1509_48119, RNA1509_54731} {RNA1310_1875.2, RNA1509_40362, RNA1509_48119, RNA1509_54731} {RNA1509_40362, RNA1509_48119, RNA1509_54731, RNA815_820}
37. MligTC455_53651 80 1.67 Mlig455_056106

Neo: -

Age: -

TNFAIP8L3 1.802 0.995 - - - - 0.807 Mlig455_056106 {REF} {Length: 2443} {Pfam: Domain of unknown function (DUF758) [PF05527.13, score=166.9]} {Human: ENSG00000183578, TNFAIP8L3, TNF alpha induced protein 8 like 3, [RH, Score=135, Expect=3e-39]} {Mouse: ENSMUSG00000074345, Tnfaip8l3, tumor necrosis factor, alpha-induced protein 8-like 3, [RH, Score=123, Expect=8e-35]; ENSMUSG00000062210, Tnfaip8, tumor necrosis factor, alpha-induced protein 8, [RH, Score=119, Expect=5e-33]} {Dmel: FBgn0034894, sigmar, salivary glands marred, [Score=83.6, Expect=9e-20]} {Smed: dd_Smed_v6_6451_0_1, dd_Smed_v6_6451_0_1, [RH, Score=137, Expect=8e-41]} {RNA1310_34371} {RNA815_33416}
38. MligTC455_33602 99 2.06 Mlig455_025373, Mlig455_025421

Neo: -

Age: Down-Up-Down

1.801 0.973 - - - - 0.828

Mlig455_025373 {REF} {Length: 1900} {RNA1310_26653} {RNA815_18547}

Mlig455_025421 {REF} {Length: 1816} {RNA1310_26653} {RNA815_18547}
39. MligTC455_34010 204 4.26 Mlig455_024028, Mlig455_024093

Neo: -

Age: Up-Down-Down

KCNC1 1.8 0.816 - - 0.984 - -

Mlig455_024028 {REF} {Length: 3896} {Pfam: Ion transport protein [PF00520.33, score=148.2]; BTB/POZ domain [PF02214.24, score=101.1]; Ion channel [PF07885.18, score=44.0]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [RH, Score=426, Expect=1e-141]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [RH, Score=424, Expect=2e-140]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [RH, Score=407, Expect=1e-133]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [RH, Score=426, Expect=5e-142]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [RH, Score=411, Expect=2e-135]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [RH, Score=408, Expect=1e-132]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [RH, Score=710, Expect=0.0]} {Celegans: WBGene00004793, shw-3, SHaW family of potassium channels; Voltage-gated K+ channel isoform 1, [RH, Score=590, Expect=0.0]} {Smed: dd_Smed_v6_9740_0_1, dd_Smed_v6_9740_0_1, [RH, Score=689, Expect=0.0]} {RNA1509_54375} {RNA1310_15083.2} {RNA815_13734}

Mlig455_024093 {REF} {Length: 3992} {Pfam: Ion transport protein [PF00520.33, score=148.2]; BTB/POZ domain [PF02214.24, score=101.1]; Ion channel [PF07885.18, score=44.0]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [RH, Score=426, Expect=1e-141]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [RH, Score=424, Expect=2e-140]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [RH, Score=407, Expect=1e-133]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [RH, Score=426, Expect=5e-142]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [RH, Score=411, Expect=2e-135]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [RH, Score=408, Expect=1e-132]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [RH, Score=710, Expect=0.0]} {Celegans: WBGene00004793, shw-3, SHaW family of potassium channels; Voltage-gated K+ channel isoform 1, [RH, Score=590, Expect=0.0]} {Smed: dd_Smed_v6_9740_0_1, dd_Smed_v6_9740_0_1, [RH, Score=689, Expect=0.0]} {RNA1509_54375} {RNA1310_15083.2} {RNA815_13734}
40. MligTC455_37644 463 9.64 Mlig455_009079, Mlig455_058102

Neo: -

Age: -

1.798 - - 0.830 0.968 - -

Mlig455_009079 {REF} {Length: 1770} {Pfam: TMEM154 protein family [PF15102.8, score=21.3]} {RNA1509_21906} {RNA1310_21443.1} {RNA815_8970.1}

Mlig455_058102 {REF} {Length: 1746} {Pfam: TMEM154 protein family [PF15102.8, score=21.6]} {RNA1509_21906} {RNA1310_21443.1} {RNA815_8970.1}
41. MligTC455_25989 157 3.27 Mlig455_048336

Neo: -

Age: -

TMEM184B 1.794 0.986 - - - - 0.808 Mlig455_048336 {REF} {Length: 2156} {TRANSSPLICED} {Pfam: Organic solute transporter Ostalpha [PF03619.18, score=289.7]} {Human: ENSG00000198792, TMEM184B, transmembrane protein 184B, [RH, Score=454, Expect=3e-158]} {Mouse: ENSMUSG00000009035, Tmem184b, transmembrane protein 184b, [RH, Score=449, Expect=1e-156]} {Dmel: FBgn0035236, CG12004, [RH, Score=462, Expect=1e-160]} {Celegans: WBGene00009574, F40E10.6, [RH, Score=469, Expect=8e-165]} {Smed: dd_Smed_v6_3881_1_1, dd_Smed_v6_3881_1_1, [RH, Score=457, Expect=1e-160]} {RNA1509_20649} {RNA1310_20202, RNA1509_20649} {RNA1509_20649, RNA815_8572}
42. MligTC455_29018 1803 37.56 Mlig455_033521

Neo: -

Age: -

1.789 0.835 - - 0.954 - - Mlig455_033521 {REF} {Length: 44} {NoTransDecoderORF}
43. MligTC455_30921 207 4.31 Mlig455_015986

Neo: -

Age: -

1.785 - - 0.796 0.989 - - Mlig455_015986 {REF} {Length: 3687} {Pfam: Phi29 scaffolding protein [PF11418.10, score=19.3]; Transcriptional regulatory protein LGE1 [PF11488.10, score=19.1]} {RNA1509_29157} {RNA1310_11784} {RNA815_12594}
44. MligTC455_16911 74 1.55 Mlig455_068641

Neo: -

Age: -

1.781 0.990 - - - - 0.791 Mlig455_068641 {REF} {Length: 965} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_6383} {RNA1310_18323.1} {RNA815_17487.2}
45. MligTC455_23937 107 2.23 Mlig455_044625

Neo: -

Age: -

TRPM3 1.781 0.968 - - - - 0.813 Mlig455_044625 {REF} {Length: 5687} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=80.1]; Ankyrin repeats (3 copies) [PF12796.9, score=74.7]; Ankyrin repeat [PF13606.8, score=59.8]; Ion transport protein [PF00520.33, score=56.9]; Ankyrin repeat [PF00023.32, score=50.8]; Ankyrin repeats (many copies) [PF13857.8, score=38.8]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=139, Expect=1e-32]; ENSG00000134160, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=135, Expect=4e-31]; ENSG00000274965, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=135, Expect=4e-31]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=142, Expect=2e-33]; ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [Score=136, Expect=1e-31]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=111, Expect=4e-24]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=112, Expect=2e-24]} {Smed: dd_Smed_v6_8382_0_1, dd_Smed_v6_8382_0_1, [Score=188, Expect=2e-48]} {RNA1509_32799} {RNA1310_1742.1} {RNA815_1771}
46. MligTC455_23938 109 2.26 Mlig455_044682

Neo: -

Age: logFC(26M/2M)=0.355

TRPM3 1.781 0.968 - - - - 0.813 Mlig455_044682 {REF} {Length: 6333} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=80.4]; Ankyrin repeats (3 copies) [PF12796.9, score=74.8]; Ankyrin repeat [PF13606.8, score=59.5]; Ion transport protein [PF00520.33, score=57.5]; Ankyrin repeat [PF00023.32, score=51.1]; Ankyrin repeats (many copies) [PF13857.8, score=38.9]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=139, Expect=2e-32]; ENSG00000134160, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=139, Expect=2e-32]; ENSG00000274965, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=139, Expect=2e-32]} {Mouse: ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [Score=141, Expect=3e-33]; ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=140, Expect=4e-33]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=112, Expect=2e-24]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=111, Expect=2e-24]} {Smed: dd_Smed_v6_8382_0_1, dd_Smed_v6_8382_0_1, [Score=192, Expect=2e-49]} {RNA1509_19611, RNA1509_32799} {RNA1310_1742.1, RNA1509_19611, RNA1509_32799} {RNA1509_19611, RNA1509_32799, RNA815_1771}
47. MligTC455_17958 490 10.21 Mlig455_068231

Neo: -

Age: logFC(26M/2M)=-0.406

CCDC83 1.78 - - - 0.954 0.826 - Mlig455_068231 {REF} {Length: 2825} {Pfam: Domain of unknown function (DUF4618) [PF15397.8, score=19.3]} {Human: ENSG00000150676, CCDC83, coiled-coil domain containing 83, [RH, Score=145, Expect=2e-38]} {Mouse: ENSMUSG00000030617, Ccdc83, coiled-coil domain containing 83, [RH, Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_16528_0_1, dd_Smed_v6_16528_0_1, [RH, Score=96.7, Expect=7e-22]} {RNA1509_34307, RNA1509_49481} {RNA1310_7992.1, RNA1509_34307, RNA1509_49481} {RNA1509_34307, RNA1509_49481, RNA815_3361.1}
48. MligTC455_47600 263 5.48 Mlig455_031414

Neo: -

Age: -

Region-enriched R2: 2.961/0.01561

NRXN1 1.778 - - - 0.955 - 0.823 Mlig455_031414 {REF} {Length: 4843} {Pfam: Laminin G domain [PF02210.26, score=235.7]; Laminin G domain [PF00054.25, score=191.1]; Syndecan domain [PF01034.22, score=26.0]; Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=22.3]; EGF-like domain [PF00008.29, score=19.4]} {Human: ENSG00000179915, NRXN1, neurexin 1, [RH, Score=379, Expect=3e-109]} {Mouse: ENSMUSG00000024109, Nrxn1, neurexin I, [Score=387, Expect=1e-112]} {Dmel: FBgn0038975, Nrx-1, Neurexin 1, [Score=313, Expect=5e-87]} {Celegans: WBGene00007799, nrx-1, NRX-1 beta isoform; NeuReXin related, [Score=179, Expect=2e-45]} {Smed: dd_Smed_v6_13697_0_1, dd_Smed_v6_13697_0_1, [Score=349, Expect=9e-101]} {RNA1509_55888} {RNA1310_9438.1} {RNA815_24775.1}
49. MligTC455_39134 462 9.62 Mlig455_011600, Mlig455_054600

Neo: -

Age: -

COPS6 1.776 - - - 0.956 0.820 -

Mlig455_011600 {REF} {Length: 1496} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=108.6]} {Mouse: ENSMUSG00000038276, Asic3, acid-sensing (proton-gated) ion channel 3, [Score=59.3, Expect=7e-09]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=78.2, Expect=5e-15]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=65.9, Expect=3e-11]} {RNA1310_87964}

Mlig455_054600 {REF} {Length: 2954} {TRANSSPLICED} {Pfam: Maintenance of mitochondrial structure and function [PF13012.8, score=85.9]; JAB1/Mov34/MPN/PAD-1 ubiquitin protease [PF01398.23, score=43.1]} {Human: ENSG00000168090, COPS6, COP9 signalosome subunit 6, [RH, Score=243, Expect=6e-78]} {Mouse: ENSMUSG00000019494, Cops6, COP9 signalosome subunit 6, [RH, Score=239, Expect=1e-76]} {Dmel: FBgn0028837, CSN6, COP9 signalosome subunit 6, [RH, Score=233, Expect=3e-74]} {Celegans: WBGene00004464, rpn-8, Proteasome Regulatory Particle, Non-ATPase-like, [Score=89.0, Expect=1e-19]} {Smed: dd_Smed_v6_4168_0_1, dd_Smed_v6_4168_0_1, [RH, Score=131, Expect=1e-35]} {RNA1509_12499, RNA1509_33634} {RNA1310_25406.1, RNA1509_33634} {RNA1509_33634, RNA815_12821.1}
50. MligTC455_22792 813 16.94 Mlig455_006911

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.573

PPP1R10 1.768 0.786 - - 0.982 - - Mlig455_006911 {REF} {Length: 4431} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=34.5} {Pfam: TFIIS helical bundle-like domain [PF08711.13, score=20.9]; Negative regulator of genetic competence (MecA) [PF05389.14, score=18.7]} {Human: ENSG00000204569, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000230995, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000238104, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000235291, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000206489, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000227804, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000231737, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]} {Mouse: ENSMUSG00000039220, Ppp1r10, protein phosphatase 1, regulatory subunit 10, [RH, Score=95.1, Expect=2e-19]} {Dmel: FBgn0053526, PNUTS, [RH, Score=87.4, Expect=4e-17]} {Smed: dd_Smed_v6_3726_0_1, dd_Smed_v6_3726_0_1, [Score=93.2, Expect=2e-19]} {RNA1509_35861, RNA1509_3759, RNA1509_41300} {RNA1310_6625, RNA1509_35861, RNA1509_41300} {RNA1509_35861, RNA1509_41300, RNA815_5489}
51. MligTC455_24758 937 19.53 Mlig455_032956

Neo: -

Age: -

Region-enriched R2: 1.593/0.03261

PFN4 1.765 0.954 - - 0.811 - - Mlig455_032956 {REF} {Length: 1604} {Pfam: Profilin [PF00235.21, score=102.2]} {Human: ENSG00000176732, PFN4, profilin family member 4, [RH, Score=99.0, Expect=4e-27]} {Mouse: ENSMUSG00000020639, Pfn4, profilin family, member 4, [RH, Score=94.4, Expect=2e-25]} {Smed: dd_Smed_v6_2107_0_1, dd_Smed_v6_2107_0_1, [RH, Score=110, Expect=7e-32]} {RNA1509_34639} {RNA1310_16901.2} {RNA815_34827}
52. MligTC455_27558 1418 29.55 Mlig455_044524

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.076

TPT1 1.765 - - - 0.964 0.801 - Mlig455_044524 {REF} {Length: 1827} {Pfam: Translationally controlled tumour protein [PF00838.19, score=59.9]} {Human: ENSG00000133112, TPT1, tumor protein, translationally-controlled 1, [Score=56.6, Expect=3e-11]} {Mouse: ENSMUSG00000060126, Tpt1, tumor protein, translationally-controlled 1, [Score=58.9, Expect=2e-12]} {Dmel: FBgn0037874, Tctp, Translationally controlled tumor protein, [Score=60.5, Expect=4e-13]} {Celegans: WBGene00009122, tct-1, Translationally-controlled tumor protein homolog, [Score=52.0, Expect=5e-10]} {Smed: dd_Smed_v6_136_0_1, dd_Smed_v6_136_0_1, [Score=67.4, Expect=4e-16]} {RNA1509_5625} {RNA1310_26303.1} {RNA815_881.1}
53. MligTC455_32874 544 11.34 Mlig455_057088

Neo: Irradiation

Age: Up-Down-Down

Region-enriched R2: 3.984/0.00029

TMC7 1.765 0.780 - - 0.985 - - Mlig455_057088 {REF} {Length: 4195} {Pfam: TMC domain [PF07810.15, score=111.1]} {Human: ENSG00000170537, TMC7, transmembrane channel like 7, [RH, Score=283, Expect=4e-84]} {Mouse: ENSMUSG00000042246, Tmc7, transmembrane channel-like gene family 7, [RH, Score=272, Expect=3e-80]} {Dmel: FBgn0267796, Tmc, Transmembrane channel-like, [RH, Score=85.5, Expect=1e-16]} {Celegans: WBGene00015177, tmc-2, Transmembrane channel-like protein 2, [RH, Score=75.5, Expect=1e-13]} {Smed: dd_Smed_v6_6619_0_1, dd_Smed_v6_6619_0_1, [RH, Score=80.9, Expect=1e-16]} {RNA1509_16303, RNA1509_28450, RNA1509_42436} {RNA1310_8759.2, RNA1509_16303, RNA1509_28450, RNA1509_42436} {RNA1509_16303, RNA1509_28450, RNA1509_42436, RNA815_2931}
54. MligTC455_18369 234 4.87 Mlig455_015695

Neo: -

Age: -

1.763 - - - 0.992 - 0.771 Mlig455_015695 {REF} {Length: 1855} {TRANSSPLICED} {RNA1509_58191} {RNA1310_66702.1} {RNA815_46154}
55. MligTC455_54129 505 10.52 Mlig455_001624

Neo: -

Age: -

1.763 - - - 0.985 0.778 - Mlig455_001624 {REF} {Length: 531} {TRANSSPLICED} {RNA1509_6997} {RNA1310_20264.3} {RNA815_34346}
56. MligTC455_09748 23 0.48 Mlig455_021244

Neo: -

Age: -

1.754 0.989 0.765 - - - - Mlig455_021244 {REF} {Length: 1248} {RNA1310_73799} {RNA815_52728}
57. MligTC455_52903 494 10.29 Mlig455_053280

Neo: -

Age: logFC(26M/2M)=-0.357

CPNE3 1.752 - - - 0.987 - 0.765 Mlig455_053280 {REF} {Length: 3157} {Pfam: C2 domain [PF00168.32, score=40.7]} {Human: ENSG00000085719, CPNE3, copine 3, [Score=107, Expect=8e-26]; ENSG00000214078, CPNE1, copine 1, [Score=103, Expect=2e-24]} {Mouse: ENSMUSG00000028228, Cpne3, copine III, [Score=99.4, Expect=3e-23]; ENSMUSG00000074643, Cpne1, copine I, [Score=98.6, Expect=2e-23]; ENSMUSG00000052560, Cpne8, copine VIII, [Score=97.1, Expect=2e-22]} {Celegans: WBGene00012128, nra-1, Nicotinic receptor-associated protein 1, [Score=69.7, Expect=3e-13]} {Smed: dd_Smed_v6_11540_0_1, dd_Smed_v6_11540_0_1, [Score=97.4, Expect=9e-23]} {RNA1509_36648} {RNA1310_30388} {RNA815_2939.1}
58. MligTC455_43180 135 2.81 Mlig455_053081

Neo: -

Age: -

1.751 - - - 0.984 0.767 - Mlig455_053081 {REF} {Length: 965} {NoTransDecoderORF} {RNA1509_53340} {RNA1310_33099, RNA1509_53340}
59. MligTC455_31339 445 9.27 Mlig455_006071, Mlig455_053223

Neo: -

Age: -

NYNRIN, POLM 1.75 - - - 0.978 0.772 -

Mlig455_006071 {REF} {Length: 7416} {Pfam: DNA polymerase beta thumb [PF14791.8, score=75.5]; Integrase zinc binding domain [PF17921.3, score=59.0]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=54.0]; Integrase core domain [PF00665.28, score=45.1]; Fingers domain of DNA polymerase lambda [PF10391.11, score=24.2]; DNA polymerase beta palm [PF14792.8, score=20.8]} {Human: ENSG00000122678, POLM, DNA polymerase mu, [Score=214, Expect=3e-59]} {Mouse: ENSMUSG00000020474, Polm, polymerase (DNA directed), mu, [RH, Score=229, Expect=2e-64]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=127, Expect=2e-29]} {RNA1509_18343} {RNA1310_8091.1} {RNA815_3041}

Mlig455_053223 {REF} {Length: 2426} {Pfam: Integrase zinc binding domain [PF17921.3, score=61.1]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=55.1]; Integrase core domain [PF00665.28, score=46.3]; Integrase core domain [PF13683.8, score=18.4]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=90.9, Expect=6e-18]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=94.0, Expect=4e-19]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=118, Expect=4e-27]} {RNA1509_18367} {RNA1310_1117.1} {RNA815_895.1}
60. MligTC455_32524 70 1.46 Mlig455_059988

Neo: -

Age: -

NR2E1 1.749 0.979 - - - - 0.770 Mlig455_059988 {REF} {Length: 3126} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=85.7]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=43.4]} {Human: ENSG00000112333, NR2E1, nuclear receptor subfamily 2 group E member 1, [RH, Score=197, Expect=1e-58]} {Mouse: ENSMUSG00000019803, Nr2e1, nuclear receptor subfamily 2, group E, member 1, [RH, Score=196, Expect=2e-58]} {Dmel: FBgn0003651, svp, seven up, [Score=162, Expect=1e-44]} {Celegans: WBGene00003657, nhr-67, Nuclear hormone receptor family member nhr-67, [Score=142, Expect=3e-38]} {Smed: dd_Smed_v6_21347_0_1, dd_Smed_v6_21347_0_1, [Score=147, Expect=3e-40]} {RNA1509_22720} {RNA1310_16022} {RNA815_25885}
61. MligTC455_37840 720 15 Mlig455_040223

Neo: -

Age: logFC(26M/2M)=0.265

Region-enriched R5: 2.081/0.00322

SLC8A1 1.746 - 0.767 - 0.979 - - Mlig455_040223 {REF} {Length: 3557} {Pfam: Calx-beta domain [PF03160.16, score=161.0]; Sodium/calcium exchanger protein [PF01699.26, score=159.8]; C-terminal extension of sodium/calcium exchanger domain [PF16494.7, score=30.8]; Domain of unknown function (DUF4843) [PF16132.7, score=28.5]} {Human: ENSG00000183023, SLC8A1, solute carrier family 8 member A1, [Score=535, Expect=5e-177]; ENSG00000100678, SLC8A3, solute carrier family 8 member A3, [Score=513, Expect=1e-168]} {Mouse: ENSMUSG00000054640, Slc8a1, solute carrier family 8 (sodium/calcium exchanger), member 1, [Score=531, Expect=1e-175]; ENSMUSG00000079055, Slc8a3, solute carrier family 8 (sodium/calcium exchanger), member 3, [Score=512, Expect=9e-169]} {Dmel: FBgn0013995, Calx, Na/Ca-exchange protein, [Score=513, Expect=5e-169]} {Celegans: WBGene00003568, ncx-3, Na/Ca eXchangers, [RH, Score=577, Expect=0.0]} {Smed: dd_Smed_v6_3303_0_1, dd_Smed_v6_3303_0_1, [Score=489, Expect=3e-160]} {RNA1509_5371} {RNA1310_3562.1} {RNA815_992.1}
62. MligTC455_53152 292 6.09 Mlig455_008262, Mlig455_040622

Neo: Int S/G2/M

Age: -

Regeneration-upregulated R2: 4.997

Regeneration-enriched R2: 4.997

TRIP13 1.746 - - - 0.959 - 0.787

Mlig455_008262 {REF} {Length: 2335} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=100.2]; AAA domain [PF13401.8, score=35.0]; AAA ATPase domain [PF13191.8, score=27.4]; AAA domain [PF13238.8, score=27.1]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=23.2]} {Human: ENSG00000071539, TRIP13, thyroid hormone receptor interactor 13, [RH, Score=314, Expect=9e-102]} {Mouse: ENSMUSG00000021569, Trip13, thyroid hormone receptor interactor 13, [RH, Score=319, Expect=6e-104]} {Dmel: FBgn0051453, pch2, pachytene checkpoint 2, [RH, Score=259, Expect=4e-81]} {Celegans: WBGene00008641, pch-2, Putative pachytene checkpoint protein 2, [RH, Score=241, Expect=3e-74]} {Smed: dd_Smed_v6_46627_0_1, dd_Smed_v6_46627_0_1, [RH, Score=257, Expect=6e-83]} {RNA1509_17149} {RNA1310_22314} {RNA815_11155}

Mlig455_040622 {REF} {Length: 2141} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=100.4]; AAA domain [PF13401.8, score=35.2]; AAA ATPase domain [PF13191.8, score=27.5]; AAA domain [PF13238.8, score=27.4]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=23.4]} {Human: ENSG00000071539, TRIP13, thyroid hormone receptor interactor 13, [RH, Score=316, Expect=6e-103]} {Mouse: ENSMUSG00000021569, Trip13, thyroid hormone receptor interactor 13, [RH, Score=320, Expect=7e-105]} {Dmel: FBgn0051453, pch2, pachytene checkpoint 2, [RH, Score=259, Expect=1e-81]} {Celegans: WBGene00008641, pch-2, Putative pachytene checkpoint protein 2, [RH, Score=242, Expect=4e-75]} {Smed: dd_Smed_v6_46627_0_1, dd_Smed_v6_46627_0_1, [RH, Score=259, Expect=3e-84]} {RNA1509_17149} {RNA1310_22314, RNA1509_17149} {RNA1509_17149, RNA815_11155}
63. MligTC455_47803 609 12.69 Mlig455_042586

Neo: -

Age: -

Region-enriched R2: 2.248/0.00320

SMKR1 1.743 0.759 - - 0.984 - - Mlig455_042586 {REF} {Length: 1831} {TRANSSPLICED} {Human: ENSG00000240204, SMKR1, small lysine rich protein 1, [RH, Score=54.3, Expect=5e-11]} {Dmel: FBgn0266615, CG45122, [Score=41.6, Expect=5e-06]} {Smed: dd_Smed_v6_10158_0_1, dd_Smed_v6_10158_0_1, [RH, Score=44.3, Expect=3e-07]} {RNA1509_37781} {RNA1310_41265, RNA1509_37781} {RNA1509_37781, RNA815_11227.2}
64. MligTC455_05098 127 2.65 Mlig455_009525, Mlig455_009531

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.095/0.01821

KCNH7 1.737 0.991 - - - - 0.746

Mlig455_009525 {REF} {Length: 2109} {Pfam: Ion transport protein [PF00520.33, score=111.8]; Ion channel [PF07885.18, score=46.1]; Cyclic nucleotide-binding domain [PF00027.31, score=36.3]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=29.8]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=528, Expect=4e-176]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=509, Expect=2e-170]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=505, Expect=9e-167]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=527, Expect=4e-175]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=510, Expect=3e-171]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=504, Expect=9e-167]} {Dmel: FBgn0003353, sei, seizure, [Score=507, Expect=2e-171]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=496, Expect=1e-169]} {Smed: dd_Smed_v6_12978_0_1, dd_Smed_v6_12978_0_1, [Score=608, Expect=0.0]} {RNA1509_56964} {RNA1310_41939} {RNA815_5858.1}

Mlig455_009531 {REF} {Length: 3631} {Pfam: Ion transport protein [PF00520.33, score=110.4]; Ion channel [PF07885.18, score=45.2]; Cyclic nucleotide-binding domain [PF00027.31, score=43.3]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=619, Expect=0.0]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=597, Expect=0.0]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=596, Expect=0.0]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=617, Expect=0.0]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=602, Expect=0.0]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=596, Expect=0.0]} {Dmel: FBgn0003353, sei, seizure, [Score=591, Expect=0.0]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=579, Expect=0.0]} {Smed: dd_Smed_v6_12978_0_4, dd_Smed_v6_12978_0_4, [RH, Score=716, Expect=0.0]} {RNA1509_56964} {RNA1310_23186, RNA1509_56964} {RNA1509_56964, RNA815_5858.2}
65. MligTC455_20624 592 12.33 Mlig455_015608

Neo: -

Age: logFC(26M/2M)=-0.899

1.736 - - - 0.988 - 0.748 Mlig455_015608 {REF} {Length: 789} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_12443} {RNA1310_14828.1} {RNA815_44673}
66. MligTC455_34349 194 4.05 Mlig455_020344

Neo: -

Age: Up-Up-Down

SLC38A7 1.735 0.951 - - - - 0.784 Mlig455_020344 {REF} {Length: 1192} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=34.4]} {Human: ENSG00000103042, SLC38A7, solute carrier family 38 member 7, [Score=75.9, Expect=8e-17]} {Mouse: ENSMUSG00000036534, Slc38a7, solute carrier family 38, member 7, [Score=77.4, Expect=2e-17]} {Smed: dd_Smed_v6_9762_0_1, dd_Smed_v6_9762_0_1, [Score=66.2, Expect=5e-14]} {RNA1509_31669} {RNA1310_11380} {RNA815_28572.1}
67. MligTC455_15569 487 10.15 Mlig455_067138, Mlig455_068636

Neo: -

Age: -

Region-enriched R2: 2.466/0.01939

1.732 - - 0.760 0.972 - -

Mlig455_067138 {REF} {Length: 332} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_27678} {RNA1310_35433} {RNA815_11024.1}

Mlig455_068636 {REF} {Length: 720} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_27678} {RNA1310_34530, RNA1509_27678} {RNA1509_27678, RNA815_11024.1}
68. MligTC455_42057 167 3.48 Mlig455_003225

Neo: -

Age: -

Region-enriched R2: 6.187/0.00004
Region-enriched R3: 4.289/0.00433

1.731 0.764 - - 0.967 - - Mlig455_003225 {REF} {Length: 943} {Pfam: Immunoreceptor tyrosine-based activation motif [PF02189.17, score=79.6]} {RNA1310_57787} {RNA815_49158}
69. MligTC455_53648 156 3.26 Mlig455_021410

Neo: -

Age: logFC(26M/2M)=0.705

1.727 - - - 0.984 - 0.743 Mlig455_021410 {REF} {Length: 1272} {TRANSSPLICED} {RNA1509_43777} {RNA1310_53190, RNA1509_43777} {RNA1509_43777, RNA815_39476}
70. MligTC455_18654 497 10.36 Mlig455_032693

Neo: -

Age: -

PPME1 1.724 0.773 - - 0.951 - - Mlig455_032693 {REF} {Length: 2557} {TRANSSPLICED} {Pfam: Alpha/beta hydrolase family [PF12697.9, score=84.1]; alpha/beta hydrolase fold [PF00561.22, score=34.3]; Serine aminopeptidase, S33 [PF12146.10, score=30.6]; alpha/beta hydrolase fold [PF07859.15, score=20.5]; PGAP1-like protein [PF07819.15, score=19.9]} {Human: ENSG00000214517, PPME1, protein phosphatase methylesterase 1, [RH, Score=273, Expect=6e-87]} {Mouse: ENSMUSG00000030718, Ppme1, protein phosphatase methylesterase 1, [RH, Score=157, Expect=3e-43]} {Dmel: FBgn0035951, CG5068, [RH, Score=262, Expect=6e-83]} {Celegans: WBGene00007188, B0464.9, Probable protein phosphatase methylesterase 1, [RH, Score=147, Expect=4e-40]} {Smed: dd_Smed_v6_5813_0_1, dd_Smed_v6_5813_0_1, [RH, Score=291, Expect=1e-94]} {RNA1509_18678, RNA1509_50525} {RNA1310_14476, RNA1509_50525} {RNA1509_50525, RNA815_3742.1}
71. MligTC455_28105 262 5.46 Mlig455_038527

Neo: -

Age: -

1.721 - - - 0.985 0.736 - Mlig455_038527 {REF} {Length: 3543} {NoTransDecoderORF} {RNA1509_32637} {RNA1310_9245.1} {RNA815_15623}
72. MligTC455_29013 169 3.51 Mlig455_000723

Neo: -

Age: Down-Up-Down

SGTB 1.719 - - - 0.986 0.733 - Mlig455_000723 {REF} {Length: 3505} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF00515.30, score=53.5]; Tetratricopeptide repeat [PF07719.19, score=48.2]; TPR repeat [PF13414.8, score=34.7]; Tetratricopeptide repeat [PF13432.8, score=32.7]; Tetratricopeptide repeat [PF13181.8, score=25.9]; Tetratricopeptide repeat [PF13428.8, score=24.6]; Tetratricopeptide repeat [PF13371.8, score=23.3]; Tetratricopeptide repeat [PF13431.8, score=21.3]} {Human: ENSG00000197860, SGTB, small glutamine rich tetratricopeptide repeat containing beta, [Score=80.5, Expect=4e-18]} {Mouse: ENSMUSG00000042743, Sgtb, small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta, [Score=79.7, Expect=4e-17]} {Dmel: FBgn0024352, Stip1, Stress induced phosphoprotein 1, [Score=63.9, Expect=2e-11]} {Celegans: WBGene00019983, sti-1, Stress-induced-phosphoprotein 1, [Score=61.6, Expect=6e-11]} {Smed: dd_Smed_v6_12396_0_1, dd_Smed_v6_12396_0_1, [Score=63.5, Expect=1e-11]} {RNA1509_38333} {RNA1310_8166} {RNA815_3887}
73. MligTC455_35063 359 7.49 Mlig455_017090

Neo: -

Age: logFC(26M/2M)=-0.336

Region-enriched R2: 2.861/0.00814

DNM1 1.719 0.766 - - 0.953 - - Mlig455_017090 {REF} {Length: 4208} {Pfam: Dynamin central region [PF01031.22, score=334.5]; Dynamin family [PF00350.25, score=184.2]; Dynamin GTPase effector domain [PF02212.20, score=80.3]; PH domain [PF00169.31, score=37.3]; 50S ribosome-binding GTPase [PF01926.25, score=21.3]} {Human: ENSG00000106976, DNM1, dynamin 1, [RH, Score=1101, Expect=0.0]; ENSG00000197959, DNM3, dynamin 3, [RH, Score=1094, Expect=0.0]; ENSG00000079805, DNM2, dynamin 2, [RH, Score=1075, Expect=0.0]} {Mouse: ENSMUSG00000026825, Dnm1, dynamin 1, [RH, Score=1102, Expect=0.0]; ENSMUSG00000040265, Dnm3, dynamin 3, [RH, Score=1089, Expect=0.0]; ENSMUSG00000033335, Dnm2, dynamin 2, [RH, Score=1074, Expect=0.0]} {Dmel: FBgn0003392, shi, shibire, [RH, Score=1074, Expect=0.0]} {Celegans: WBGene00001130, dyn-1, Dynamin, [RH, Score=984, Expect=0.0]} {Smed: dd_Smed_v6_6863_0_1, dd_Smed_v6_6863_0_1, [RH, Score=1068, Expect=0.0]} {RNA1509_31451, RNA1509_50695} {RNA1310_8903.1, RNA1509_31451, RNA1509_50695} {RNA1509_31451, RNA1509_50695, RNA815_1703.1}
74. MligTC455_29027 116 2.42 Mlig455_015155

Neo: -

Age: -

SERP2 1.718 - - - 0.976 0.742 - Mlig455_015155 {REF} {Length: 702} {TRANSSPLICED} {Pfam: Ribosome associated membrane protein RAMP4 [PF06624.14, score=92.7]} {Human: ENSG00000151778, SERP2, stress associated endoplasmic reticulum protein family member 2, [RH, Score=92.4, Expect=2e-26]} {Mouse: ENSMUSG00000052584, Serp2, stress-associated endoplasmic reticulum protein family member 2, [RH, Score=92.4, Expect=1e-26]} {Dmel: FBgn0047135, CG32276, [RH, Score=94.7, Expect=1e-27]} {Celegans: WBGene00010337, F59F4.2, [RH, Score=91.3, Expect=2e-26]} {Smed: dd_Smed_v6_304_0_1, dd_Smed_v6_304_0_1, [RH, Score=111, Expect=2e-34]} {RNA1509_15112} {RNA1310_71915} {RNA815_35016}
75. MligTC455_46762 101 2.11 Mlig455_014615

Neo: -

Age: -

PANK4 1.718 0.982 - - - - 0.736 Mlig455_014615 {REF} {Length: 3653} {Pfam: Fumble [PF03630.16, score=86.8]} {Human: ENSG00000157881, PANK4, pantothenate kinase 4, [Score=67.8, Expect=1e-11]; ENSG00000273494, PANK4, pantothenate kinase 4, [Score=67.8, Expect=1e-11]} {Mouse: ENSMUSG00000018846, Pank3, pantothenate kinase 3, [Score=53.1, Expect=2e-07]} {Celegans: WBGene00004068, pnk-1, PaNtothenate Kinase, [Score=57.0, Expect=9e-09]} {Smed: dd_Smed_v6_994_0_1, dd_Smed_v6_994_0_1, [Score=117, Expect=1e-29]} {RNA1509_52856} {RNA1310_25103, RNA1509_52856} {RNA1509_52856, RNA815_12785.1}
76. MligTC455_37959 177 3.69 Mlig455_038764

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.399

SCNN1B 1.714 - - - 0.973 - 0.741 Mlig455_038764 {REF} {Length: 3158} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=192.0]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=49.7, Expect=1e-05]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=68.9, Expect=7e-12]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=57.4, Expect=2e-08]} {Smed: dd_Smed_v6_26855_0_1, dd_Smed_v6_26855_0_1, [Score=168, Expect=4e-45]} {RNA1509_35658, RNA1509_58401} {RNA1310_10317.1, RNA1509_35658, RNA1509_58401} {RNA1509_35658, RNA1509_58401, RNA815_3305}
77. MligTC455_04206 850 17.72 Mlig455_060960

Neo: -

Age: logFC(26M/2M)=-0.260

Region-enriched R4: 1.139/0.02732

ZNF569 1.713 0.758 - - 0.955 - - Mlig455_060960 {REF} {Length: 4764} {Pfam: C2H2-type zinc finger [PF13894.8, score=86.0]; Zinc finger, C2H2 type [PF00096.28, score=60.2]; Drought induced 19 protein (Di19), zinc-binding [PF05605.14, score=29.1]; Zinc-finger double domain [PF13465.8, score=26.1]; Zinc finger C2H2-type, 3 repeats [PF18868.3, score=24.6]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=22.4]} {Human: ENSG00000196437, ZNF569, zinc finger protein 569, [Score=77.4, Expect=7e-14]; ENSG00000090612, ZNF268, zinc finger protein 268, [Score=74.3, Expect=9e-13]} {Mouse: ENSMUSG00000096916, Zfp850, zinc finger protein 850, [Score=77.0, Expect=7e-14]; ENSMUSG00000033669, Zfp7, zinc finger protein 7, [Score=74.3, Expect=5e-13]} {Dmel: FBgn0037120, CG11247, [Score=50.1, Expect=9e-06]} {Smed: dd_Smed_v6_10676_0_1, dd_Smed_v6_10676_0_1, [Score=52.8, Expect=6e-07]} {RNA1509_22736, RNA1509_25692, RNA1509_6044} {RNA1310_4035.1, RNA1509_22736, RNA1509_25692, RNA1509_6044} {RNA1509_22736, RNA1509_25692, RNA1509_6044, RNA815_2236}
78. MligTC455_44836 330 6.88 Mlig455_002007, Mlig455_002209

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.455

TRIM2, TRIM3 1.713 0.994 - - - - 0.719

Mlig455_002007 {REF} {Length: 3003} {TRANSSPLICED} {Pfam: NHL repeat [PF01436.23, score=60.9]; 6-bladed beta-propeller [PF17170.6, score=32.1]; B-box zinc finger [PF00643.26, score=30.2]} {Human: ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=132, Expect=4e-31]; ENSG00000110171, TRIM3, tripartite motif containing 3, [Score=132, Expect=4e-31]; ENSG00000206557, TRIM71, tripartite motif containing 71, [Score=128, Expect=9e-30]} {Mouse: ENSMUSG00000036989, Trim3, tripartite motif-containing 3, [Score=132, Expect=3e-31]; ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=132, Expect=2e-31]} {Dmel: FBgn0265356, tn, thin, [Score=102, Expect=6e-22]} {Celegans: WBGene00003026, lin-41, [Score=62.8, Expect=8e-10]} {Smed: dd_Smed_v6_26017_0_1, dd_Smed_v6_26017_0_1, [Score=63.5, Expect=2e-10]} {RNA1509_19290} {RNA1310_4861.1} {RNA815_7213.1}

Mlig455_002209 {REF} {Length: 3098} {Pfam: NHL repeat [PF01436.23, score=60.5]; 6-bladed beta-propeller [PF17170.6, score=37.8]; B-box zinc finger [PF00643.26, score=30.2]} {Human: ENSG00000110171, TRIM3, tripartite motif containing 3, [Score=134, Expect=1e-31]; ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=134, Expect=1e-31]; ENSG00000206557, TRIM71, tripartite motif containing 71, [Score=131, Expect=1e-30]} {Mouse: ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=134, Expect=6e-32]; ENSMUSG00000036989, Trim3, tripartite motif-containing 3, [Score=134, Expect=9e-32]} {Dmel: FBgn0265356, tn, thin, [Score=105, Expect=1e-22]} {Celegans: WBGene00003026, lin-41, [Score=65.5, Expect=1e-10]} {Smed: dd_Smed_v6_26017_0_1, dd_Smed_v6_26017_0_1, [Score=66.2, Expect=2e-11]} {RNA1509_19290} {RNA1310_4861.1} {RNA815_7213.1}
79. MligTC455_50488 347 7.22 Mlig455_026193

Neo: -

Age: -

INPP1 1.712 - - - 0.976 - 0.736 Mlig455_026193 {REF} {Length: 2896} {Pfam: Inositol monophosphatase family [PF00459.27, score=111.3]} {Human: ENSG00000151689, INPP1, inositol polyphosphate-1-phosphatase, [RH, Score=262, Expect=8e-84]} {Mouse: ENSMUSG00000026102, Inpp1, inositol polyphosphate-1-phosphatase, [RH, Score=294, Expect=1e-96]} {Dmel: FBgn0016672, Ipp, Inositol polyphosphate 1-phosphatase, [RH, Score=241, Expect=2e-76]} {Celegans: WBGene00044063, bpnt-1, 3'(2'), 5'-BisPhosphate NucleoTidase 1 homolog, [Score=75.1, Expect=6e-15]} {Smed: dd_Smed_v6_9612_0_1, dd_Smed_v6_9612_0_1, [RH, Score=189, Expect=2e-56]} {RNA1509_17015} {RNA1310_9873, RNA1509_17015} {RNA1509_17015, RNA815_6008}
80. MligTC455_51339 75 1.56 Mlig455_024282

Neo: -

Age: -

1.708 0.992 0.716 - - - - Mlig455_024282 {REF} {Length: 2404} {RNA1310_48051} {RNA815_14784}
81. MligTC455_41761 655 13.65 Mlig455_020225

Neo: Irradiation

Age: -

Region-enriched R5: 1.227/0.00118

PTPRZ1 1.704 0.738 - - 0.966 - - Mlig455_020225 {REF} {Length: 5464} {TRANSSPLICED} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=409.3]; Fibronectin type III domain [PF00041.23, score=83.6]; Dual specificity phosphatase, catalytic domain [PF00782.22, score=24.2]} {Human: ENSG00000106278, PTPRZ1, protein tyrosine phosphatase, receptor type Z1, [RH, Score=492, Expect=4e-149]; ENSG00000144724, PTPRG, protein tyrosine phosphatase, receptor type G, [RH, Score=492, Expect=4e-149]} {Mouse: ENSMUSG00000068748, Ptprz1, protein tyrosine phosphatase, receptor type Z, polypeptide 1, [RH, Score=491, Expect=6e-145]; ENSMUSG00000021745, Ptprg, protein tyrosine phosphatase, receptor type, G, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0004369, Ptp99A, Protein tyrosine phosphatase 99A, [RH, Score=469, Expect=9e-143]} {Celegans: WBGene00004215, ptp-3, Tyrosine-protein phosphatase Lar-like, [Score=348, Expect=9e-101]} {Smed: dd_Smed_v6_6997_0_1, dd_Smed_v6_6997_0_1, [RH, Score=564, Expect=9e-177]} {RNA1509_4639} {RNA1310_810} {RNA815_3651}
82. MligTC455_17224 155 3.22 Mlig455_069916

Neo: -

Age: -

TBPL2 1.701 - - - 0.988 0.713 - Mlig455_069916 {REF} {Length: 699} {Pfam: Transcription factor TFIID (or TATA-binding protein, TBP) [PF00352.23, score=46.0]} {Human: ENSG00000182521, TBPL2, TATA-box binding protein like 2, [Score=47.0, Expect=1e-06]; ENSG00000112592, TBP, TATA-box binding protein, [Score=45.1, Expect=5e-06]} {Mouse: ENSMUSG00000061809, Tbpl2, TATA box binding protein like 2, [Score=48.1, Expect=3e-07]} {Dmel: FBgn0003687, Tbp, TATA binding protein, [Score=48.1, Expect=2e-07]} {Celegans: WBGene00006577, tlf-1, TBP-Like Factor; TBP-like factor, [Score=45.8, Expect=1e-06]} {RNA1509_12203} {RNA1310_37970} {RNA815_7432}
83. MligTC455_26365 154 3.21 Mlig455_013552

Neo: -

Age: logFC(26M/2M)=-0.510

Region-enriched R4: 3.332/0.01426

MAP3K15 1.699 - 0.713 - 0.986 - - Mlig455_013552 {REF} {Length: 2480} {Pfam: Protein kinase domain [PF00069.27, score=137.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=96.5]; Fungal protein kinase [PF17667.3, score=25.9]; Phosphotransferase enzyme family [PF01636.25, score=21.0]} {Human: ENSG00000180815, MAP3K15, mitogen-activated protein kinase kinase kinase 15, [Score=122, Expect=3e-30]; ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=117, Expect=4e-29]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=117, Expect=6e-29]; ENSMUSG00000026277, Stk25, serine/threonine kinase 25 (yeast), [Score=112, Expect=1e-27]; ENSMUSG00000031112, Stk26, serine/threonine kinase 26, [Score=112, Expect=4e-28]; ENSMUSG00000020272, Stk10, serine/threonine kinase 10, [Score=112, Expect=3e-27]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=118, Expect=3e-29]} {Celegans: WBGene00003144, max-2, Serine/threonine-protein kinase max-2, [Score=102, Expect=2e-25]} {Smed: dd_Smed_v6_2030_0_14, dd_Smed_v6_2030_0_14, [Score=117, Expect=7e-30]} {RNA1509_48626} {RNA1310_22200.1} {RNA815_5323.2}
84. MligTC455_53703 1243 25.89 Mlig455_035820

Neo: -

Age: -

MEF2A 1.699 - - - 0.982 - 0.717 Mlig455_035820 {REF} {Length: 3672} {TRANSSPLICED} {Pfam: SRF-type transcription factor (DNA-binding and dimerisation domain) [PF00319.20, score=86.4]} {Human: ENSG00000068305, MEF2A, myocyte enhancer factor 2A, [RH, Score=194, Expect=4e-56]; ENSG00000081189, MEF2C, myocyte enhancer factor 2C, [RH, Score=192, Expect=8e-56]; ENSG00000116604, MEF2D, myocyte enhancer factor 2D, [RH, Score=190, Expect=2e-54]} {Mouse: ENSMUSG00000030557, Mef2a, myocyte enhancer factor 2A, [RH, Score=194, Expect=2e-56]; ENSMUSG00000005583, Mef2c, myocyte enhancer factor 2C, [RH, Score=193, Expect=4e-56]; ENSMUSG00000001419, Mef2d, myocyte enhancer factor 2D, [RH, Score=190, Expect=8e-55]} {Dmel: FBgn0011656, Mef2, Myocyte enhancer factor 2, [RH, Score=177, Expect=7e-50]} {Celegans: WBGene00003182, mef-2, Related to vertebrate MEF2 transcription factor, [RH, Score=188, Expect=7e-56]} {Smed: dd_Smed_v6_5317_0_1, dd_Smed_v6_5317_0_1, [RH, Score=171, Expect=1e-47]} {RNA1509_17387, RNA1509_26244, RNA1509_34022, RNA1509_49246, RNA1509_50913, RNA1509_56175} {RNA1310_3049.1, RNA1509_17387, RNA1509_26244, RNA1509_34022, RNA1509_49246, RNA1509_50913, RNA1509_56175} {RNA1509_17387, RNA1509_26244, RNA1509_34022, RNA1509_49246, RNA1509_50913, RNA1509_56175, RNA815_6369}
85. MligTC455_52703 503 10.48 Mlig455_067967

Neo: -

Age: Up-Down-Up

DSCAM 1.697 0.722 - - 0.975 - - Mlig455_067967 {REF} {Length: 7940} {Pfam: Fibronectin type III domain [PF00041.23, score=181.2]; Immunoglobulin domain [PF13927.8, score=132.1]; Immunoglobulin I-set domain [PF07679.18, score=91.0]; Immunoglobulin domain [PF13895.8, score=77.5]; Immunoglobulin domain [PF00047.27, score=62.1]; Purple acid Phosphatase, N-terminal domain [PF16656.7, score=49.3]; Immunoglobulin V-set domain [PF07686.19, score=46.5]} {Human: ENSG00000171587, DSCAM, DS cell adhesion molecule, [RH, Score=242, Expect=2e-63]; ENSG00000177103, DSCAML1, DS cell adhesion molecule like 1, [RH, Score=239, Expect=3e-62]} {Mouse: ENSMUSG00000050272, Dscam, DS cell adhesion molecule, [RH, Score=238, Expect=3e-62]; ENSMUSG00000032087, Dscaml1, DS cell adhesion molecule like 1, [RH, Score=238, Expect=2e-62]} {Dmel: FBgn0263219, Dscam4, Down syndrome cell adhesion molecule 4, [Score=221, Expect=4e-57]} {Celegans: WBGene00004215, ptp-3, Tyrosine-protein phosphatase Lar-like, [Score=79.7, Expect=2e-14]} {Smed: dd_Smed_v6_3024_0_1, dd_Smed_v6_3024_0_1, [RH, Score=330, Expect=1e-90]} {RNA1509_2497} {RNA1310_1699.1} {RNA815_16029}
86. MligTC455_30835 337 7.02 Mlig455_058095

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.267

HDAC11 1.696 - - - 0.965 - 0.731 Mlig455_058095 {REF} {Length: 2115} {TRANSSPLICED} {Pfam: Histone deacetylase domain [PF00850.21, score=164.2]} {Human: ENSG00000163517, HDAC11, histone deacetylase 11, [RH, Score=412, Expect=5e-144]} {Mouse: ENSMUSG00000034245, Hdac11, histone deacetylase 11, [RH, Score=411, Expect=1e-143]} {Dmel: FBgn0051119, HDAC11, Histone deacetylase 11, [RH, Score=325, Expect=6e-110]} {Celegans: WBGene00007953, hda-11, Histone DeAcetylase, [RH, Score=291, Expect=4e-97]} {Smed: dd_Smed_v6_3401_0_4, dd_Smed_v6_3401_0_4, [RH, Score=320, Expect=1e-108]} {RNA1509_25531} {RNA1310_11718} {RNA815_3768.1}
87. MligTC455_53545 764 15.92 Mlig455_025899

Neo: -

Age: logFC(26M/2M)=0.796

HELT 1.695 0.740 - - 0.955 - - Mlig455_025899 {REF} {Length: 2919} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=43.8]} {Human: ENSG00000187821, HELT, helt bHLH transcription factor, [Score=68.2, Expect=1e-12]} {Mouse: ENSMUSG00000047171, Helt, helt bHLH transcription factor, [Score=68.6, Expect=6e-13]} {Dmel: FBgn0027788, Hey, Hairy/E(spl)-related with YRPW motif, [Score=66.2, Expect=1e-11]} {Smed: dd_Smed_v6_22479_0_1, dd_Smed_v6_22479_0_1, [Score=60.5, Expect=3e-10]} {RNA1509_12426, RNA1509_49122} {RNA1310_18992.1, RNA1509_49122} {RNA1509_49122, RNA815_16883}
88. MligTC455_36768 627 13.06 Mlig455_047617, Mlig455_047668

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.354

Region-enriched R4: 2.336/0.01334

CASP3 1.691 - - - 0.986 - 0.705

Mlig455_047617 {REF} {Length: 5415} {Pfam: Caspase domain [PF00656.24, score=97.8]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=63.5, Expect=3e-10]} {Mouse: ENSMUSG00000025888, Casp1, caspase 1, [Score=67.4, Expect=2e-11]} {Dmel: FBgn0028381, Decay, Death executioner caspase related to Apopain/Yama, [Score=49.7, Expect=6e-06]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=60.8, Expect=1e-09]} {RNA1509_18240} {RNA1310_3181} {RNA815_2826}

Mlig455_047668 {REF} {Length: 3971} {Pfam: Caspase domain [PF00656.24, score=97.8]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=63.5, Expect=3e-10]} {Mouse: ENSMUSG00000025888, Casp1, caspase 1, [Score=67.4, Expect=2e-11]} {Dmel: FBgn0028381, Decay, Death executioner caspase related to Apopain/Yama, [Score=49.7, Expect=6e-06]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=60.8, Expect=1e-09]} {RNA1509_18240, RNA1509_55746} {RNA1310_3181, RNA1509_55746} {RNA1509_55746, RNA815_2826}
89. MligTC455_24383 293 6.11 Mlig455_010723

Neo: Irradiation

Age: -

Region-enriched R5: 1.611/0.00891

ZNF652 1.687 - - 0.700 0.987 - - Mlig455_010723 {REF} {Length: 2471} {TRANSSPLICED} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=42.7]; C2H2-type zinc finger [PF13894.8, score=34.4]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=31.6]; Zinc-finger double domain [PF13465.8, score=26.2]; C2H2-type zinc finger [PF13912.8, score=22.7]; Zinc-finger of C2H2 type [PF12874.9, score=21.1]} {Human: ENSG00000198740, ZNF652, zinc finger protein 652, [Score=72.4, Expect=1e-13]; ENSG00000187792, ZNF70, zinc finger protein 70, [Score=70.9, Expect=4e-13]; ENSG00000114853, ZBTB47, zinc finger and BTB domain containing 47, [Score=70.1, Expect=1e-12]; ENSG00000130182, ZSCAN10, zinc finger and SCAN domain containing 10, [Score=68.9, Expect=2e-12]} {Mouse: ENSMUSG00000074519, Zfp971, zinc finger protein 971, [Score=72.4, Expect=8e-14]; ENSMUSG00000013419, Zfp651, zinc finger protein 651, [Score=70.5, Expect=5e-13]; ENSMUSG00000029127, Zbtb49, zinc finger and BTB domain containing 49, [Score=69.3, Expect=1e-12]; ENSMUSG00000059475, Zfp426, zinc finger protein 426, [Score=68.9, Expect=1e-12]} {Dmel: FBgn0033782, sug, sugarbabe, [Score=78.2, Expect=6e-16]} {Celegans: WBGene00004335, ref-2, REgulator of Fusion, [Score=64.3, Expect=1e-11]} {Smed: dd_Smed_v6_17566_0_1, dd_Smed_v6_17566_0_1, [Score=77.0, Expect=1e-15]} {RNA1509_37341} {RNA1310_19294.1, RNA1509_37341} {RNA1509_37341, RNA815_13553}
90. MligTC455_19099 94 1.95 Mlig455_025635

Neo: -

Age: -

TRHR 1.681 0.976 - - - - 0.705 Mlig455_025635 {REF} {Length: 3815} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=39.5]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=18.8]} {Human: ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=60.8, Expect=2e-09]} {Mouse: ENSMUSG00000038760, Trhr, thyrotropin releasing hormone receptor, [Score=58.9, Expect=6e-09]; ENSMUSG00000039079, Trhr2, thyrotropin releasing hormone receptor 2, [Score=57.8, Expect=1e-08]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=65.9, Expect=3e-11]} {Celegans: WBGene00019445, frpr-12, FMRFamide Peptide Receptor family, [Score=56.2, Expect=2e-08]} {Smed: dd_Smed_v6_13282_0_1, dd_Smed_v6_13282_0_1, [RH, Score=223, Expect=8e-68]} {RNA1509_60180} {RNA1310_18827} {RNA815_22334}
91. MligTC455_37577 942 19.63 Mlig455_032156, Mlig455_032162, Mlig455_067630

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.122/0.04027

1.676 - - - 0.970 - 0.706

Mlig455_032156 {REF} {Length: 1459} {RNA1310_42557} {RNA815_22443}

Mlig455_032162 {REF} {Length: 1492} {RNA1310_8269} {RNA815_22443}

Mlig455_067630 {REF} {Length: 960} {RNA1310_42557} {RNA815_22443}
92. MligTC455_19818 455 9.49 Mlig455_030794, Mlig455_037967

Neo: -

Age: Down-Up-Down

1.671 - - - 0.971 - 0.700

Mlig455_030794 {REF} {Length: 582} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45712} {RNA1310_64066} {RNA815_23034.1}

Mlig455_037967 {REF} {Length: 221} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45712} {RNA1310_64066} {RNA815_23034.1}
93. MligTC455_30344 114 2.38 Mlig455_029580

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.485

TRAF6 1.665 0.963 - - - 0.702 - Mlig455_029580 {REF} {Length: 9635} {Pfam: TRAF-type zinc finger [PF02176.20, score=40.4]} {Human: ENSG00000175104, TRAF6, TNF receptor associated factor 6, [Score=91.7, Expect=4e-19]} {Mouse: ENSMUSG00000026942, Traf2, TNF receptor-associated factor 2, [Score=89.4, Expect=1e-18]; ENSMUSG00000027164, Traf6, TNF receptor-associated factor 6, [Score=86.7, Expect=1e-17]; ENSMUSG00000021277, Traf3, TNF receptor-associated factor 3, [Score=86.3, Expect=2e-17]} {Smed: dd_Smed_v6_168_0_1, dd_Smed_v6_168_0_1, [Score=91.7, Expect=1e-19]} {RNA1509_57505, RNA1509_8906} {RNA1310_1712.2, RNA1509_57505, RNA1509_8906} {RNA1509_57505, RNA1509_8906, RNA815_474.1}
94. MligTC455_32688 472 9.83 Mlig455_059903

Neo: -

Age: -

ZDHHC11 1.664 - - - 0.954 0.710 - Mlig455_059903 {REF} {Length: 3454} {TRANSSPLICED} {Pfam: DHHC palmitoyltransferase [PF01529.22, score=96.6]} {Human: ENSG00000188818, ZDHHC11, zinc finger DHHC-type containing 11, [Score=164, Expect=1e-44]; ENSG00000206077, ZDHHC11B, zinc finger DHHC-type containing 11B, [Score=159, Expect=7e-43]} {Mouse: ENSMUSG00000069189, Zdhhc11, zinc finger, DHHC domain containing 11, [Score=162, Expect=1e-44]} {Dmel: FBgn0031239, CG17075, [Score=141, Expect=5e-35]} {Celegans: WBGene00020694, dhhc-11, Palmitoyltransferase, [RH, Score=107, Expect=2e-25]} {Smed: dd_Smed_v6_11261_0_1, dd_Smed_v6_11261_0_1, [Score=202, Expect=9e-58]} {RNA1509_18200, RNA1509_52040, RNA1509_58411} {RNA1310_9054, RNA1509_52040, RNA1509_58411} {RNA1509_52040, RNA1509_58411, RNA815_11274}
95. MligTC455_35640 622 12.96 Mlig455_025127

Neo: -

Age: -

KREMEN1 1.663 - - - 0.960 - 0.703 Mlig455_025127 {REF} {Length: 4542} {Pfam: WSC domain [PF01822.21, score=445.5]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=55.5, Expect=4e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=59.7, Expect=2e-08]; ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=57.8, Expect=5e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=59.3, Expect=2e-08]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=56.2, Expect=1e-07]} {RNA1509_10855} {RNA1310_564} {RNA815_597.1}
96. MligTC455_34350 159 3.31 Mlig455_041282

Neo: -

Age: -

SLC38A7 1.659 0.952 - - - - 0.707 Mlig455_041282 {REF} {Length: 2040} {TRANSSPLICED} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=185.0]; Tryptophan/tyrosine permease family [PF03222.15, score=21.5]} {Human: ENSG00000103042, SLC38A7, solute carrier family 38 member 7, [RH, Score=286, Expect=3e-92]} {Mouse: ENSMUSG00000036534, Slc38a7, solute carrier family 38, member 7, [RH, Score=290, Expect=9e-94]} {Smed: dd_Smed_v6_9762_0_1, dd_Smed_v6_9762_0_1, [RH, Score=236, Expect=5e-73]} {RNA1509_31669, RNA1509_45333} {RNA1310_11380, RNA1509_31669, RNA1509_45333} {RNA1509_31669, RNA1509_45333, RNA815_15209}
97. MligTC455_27298 94 1.95 Mlig455_050684

Neo: -

Age: -

1.658 0.951 - - - - 0.707 Mlig455_050684 {REF} {Length: 282} {NoTransDecoderORF} {RNA1509_45642} {RNA1310_133889}
98. MligTC455_43328 180 3.75 Mlig455_007116

Neo: -

Age: Up-Down-Down

Region-enriched R5: 2.390/0.01781

SMURF1 1.657 0.954 - - - - 0.703 Mlig455_007116 {REF} {Length: 5151} {Pfam: HECT-domain (ubiquitin-transferase) [PF00632.27, score=302.6]; WW domain [PF00397.28, score=64.1]; C2 domain [PF00168.32, score=48.5]} {Human: ENSG00000198742, SMURF1, SMAD specific E3 ubiquitin protein ligase 1, [RH, Score=734, Expect=0.0]; ENSG00000284126, SMURF1, SMAD specific E3 ubiquitin protein ligase 1, [RH, Score=734, Expect=0.0]; ENSG00000108854, SMURF2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=728, Expect=0.0]} {Mouse: ENSMUSG00000018363, Smurf2, SMAD specific E3 ubiquitin protein ligase 2, [RH, Score=729, Expect=0.0]} {Dmel: FBgn0259174, Nedd4, [Score=408, Expect=1e-131]} {Celegans: WBGene00022358, Y92H12A.2, E3 ubiquitin-protein ligase, [Score=400, Expect=1e-132]} {Smed: dd_Smed_v6_4374_0_1, dd_Smed_v6_4374_0_1, [Score=395, Expect=7e-128]} {RNA1509_42014} {RNA1310_6371, RNA1509_42014} {RNA1509_42014, RNA815_15558}
99. MligTC455_22825 35 0.73 Mlig455_065147

Neo: -

Age: Up-Down-Down

0.997 0.997 - - - - - Mlig455_065147 {REF} {Length: 3482} {RNA1509_31773} {RNA1310_14428} {RNA815_10931}
100. MligTC455_46490 159 3.31 Mlig455_023332

Neo: Int S/G2/M

Age: Down-Up-Down

Regeneration-upregulated R4: 4.570

Regeneration-enriched R4: 4.570

CLTA 0.997 0.997 - - - - - Mlig455_023332 {REF} {Length: 1050} {Pfam: Clathrin light chain [PF01086.19, score=73.7]} {Human: ENSG00000122705, CLTA, clathrin light chain A, [Score=63.9, Expect=6e-13]} {Mouse: ENSMUSG00000028478, Clta, clathrin, light polypeptide (Lca), [Score=64.7, Expect=2e-13]} {RNA1509_23129} {RNA1310_38212.1} {RNA815_14039}

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