Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_29984 | 53 | 1.10 | Mlig455_039009 | Neo: - Age: - |
Mlig455_039009 {REF} {Length: 2751} {Pfam: Mab-21 protein [PF03281.16, score=23.2]} {RNA1509_59266} {RNA1310_36780} {RNA815_5358.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -1.106 | 1.334 | 0.65915 | 1.00000 | |
RegionR2 | 1.835 | 1.334 | 0.08320 | 0.35391 | |
RegionR3 | 0.653 | 1.334 | 0.39408 | 0.92388 | |
RegionR4 | -1.498 | 1.334 | 0.14585 | 0.39252 | |
RegionR5 | -1.979 | 1.334 | 0.03997 | 0.15940 | |
RegionR6 | 0.869 | 1.334 | 0.28353 | 0.87390 | |
RegionR7 | 0.487 | 1.334 | 0.69661 | 1.00000 | |
RegionR8 | 0.738 | 1.334 | 0.63229 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -2.208 | 1.334 | 0.73748 | 1.00000 | |
RegenerationR2 | 0.629 | 1.334 | 0.36130 | 0.78989 | |
RegenerationR3 | -0.112 | 1.334 | 0.92856 | 1.00000 | |
RegenerationR4 | -1.098 | 1.334 | 0.29023 | 0.73432 | |
RegenerationR5 | -0.271 | 1.334 | 0.72936 | 0.96330 | |
RegenerationR6 | -2.711 | 1.334 | 0.04805 | 0.27423 | |
RegenerationBL | -1.649 | 1.334 | 0.39481 | 0.76346 | |
RegenerationTP | 1.167 | 1.334 | 0.35618 | 0.79706 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_29984 | 53 | 1.1 | Mlig455_039009 | Neo: - Age: - |
5 | 1.000 | 1.000 | 1.000 | 1.000 | - | 1.000 | Mlig455_039009 {REF} {Length: 2751} {Pfam: Mab-21 protein [PF03281.16, score=23.2]} {RNA1509_59266} {RNA1310_36780} {RNA815_5358.1} | |
2. | MligTC455_52528 | 145 | 3.03 | Mlig455_025895 | Neo: - Age: logFC(26M/2M)=-0.670 |
FLVCR2 | 1.889 | - | - | - | 0.929 | - | 0.960 | Mlig455_025895 {REF} {Length: 2218} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=82.0]; Sugar (and other) transporter [PF00083.26, score=18.7]} {Human: ENSG00000119686, FLVCR2, feline leukemia virus subgroup C cellular receptor family member 2, [RH, Score=364, Expect=4e-119]} {Mouse: ENSMUSG00000034258, Flvcr2, feline leukemia virus subgroup C cellular receptor 2, [RH, Score=368, Expect=2e-120]} {Dmel: FBgn0033196, CG1358, [RH, Score=350, Expect=1e-114]} {Celegans: WBGene00015632, C09D4.1, Uncharacterized MFS-type transporter C09D4.1, [RH, Score=358, Expect=2e-116]} {Smed: dd_Smed_v6_7578_0_1, dd_Smed_v6_7578_0_1, [Score=335, Expect=3e-109]} {RNA1509_31725} {RNA1310_8852.1, RNA1509_31725} {RNA1509_31725, RNA815_14234} |
3. | MligTC455_27900 | 122 | 2.55 | Mlig455_012166 | Neo: - Age: - |
RNF213 | 1.857 | - | - | - | 0.898 | - | 0.959 | Mlig455_012166 {REF} {Length: 15248} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=50.6]; AAA domain (dynein-related subfamily) [PF07728.16, score=47.7]; P-loop containing dynein motor region [PF12775.9, score=42.8]; AAA domain [PF13173.8, score=22.7]; Sigma-54 interaction domain [PF14532.8, score=20.3]} {Human: ENSG00000173821, RNF213, ring finger protein 213, [Score=404, Expect=1e-111]} {Mouse: ENSMUSG00000070327, Rnf213, ring finger protein 213, [Score=403, Expect=2e-111]} {RNA1509_34087, RNA1509_4697} {RNA1310_300.1, RNA1509_34087, RNA1509_4697} {RNA1509_34087, RNA1509_4697, RNA815_205.1} |
4. | MligTC455_27904 | 110 | 2.29 | Mlig455_028965 | Neo: - Age: - |
1.798 | - | - | - | 0.845 | - | 0.953 | Mlig455_028965 {REF} {Length: 8009} {Mouse: ENSMUSG00000070327, Rnf213, ring finger protein 213, [Score=50.4, Expect=7e-06]} {RNA1509_4697} {RNA1310_228} {RNA815_3412.1} | |
5. | MligTC455_44986 | 2417 | 50.36 | Mlig455_002882 | Neo: - Age: logFC(26M/2M)=-0.453 |
1.77 | - | - | 0.814 | 0.956 | - | - | Mlig455_002882 {REF} {Length: 1187} {RNA1509_10653, RNA1509_6260} {RNA1310_22176, RNA1509_10653, RNA1509_6260} {RNA1509_10653, RNA1509_6260, RNA815_9068} | |
6. | MligTC455_38828 | 995 | 20.73 | Mlig455_009774, Mlig455_054924 | Neo: - Age: Down-Up-Down Region-enriched R8: 1.773/0.01787 |
CELSR2 | 1.767 | - | - | 0.788 | 0.979 | - | - | Mlig455_009774 {REF} {Length: 2779} {Pfam: Cadherin domain [PF00028.19, score=114.6]} {Human: ENSG00000143126, CELSR2, cadherin EGF LAG seven-pass G-type receptor 2, [Score=110, Expect=3e-24]} {Mouse: ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [Score=107, Expect=3e-23]} {Dmel: FBgn0039294, Cad96Cb, Cadherin 96Cb, [RH, Score=133, Expect=7e-32]} {Celegans: WBGene00000401, cdh-9, CaDHerin family, [RH, Score=79.7, Expect=3e-15]} {Smed: dd_Smed_v6_14410_0_1, dd_Smed_v6_14410_0_1, [Score=77.0, Expect=2e-14]} {RNA1509_6574} {RNA1310_7530, RNA1509_6574} {RNA1509_6574, RNA815_2409} Mlig455_054924 {REF} {Length: 2736} {Pfam: Cadherin domain [PF00028.19, score=113.4]} {Human: ENSG00000143126, CELSR2, cadherin EGF LAG seven-pass G-type receptor 2, [Score=108, Expect=1e-23]} {Mouse: ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [Score=104, Expect=2e-22]} {Dmel: FBgn0039294, Cad96Cb, Cadherin 96Cb, [RH, Score=130, Expect=5e-31]} {Celegans: WBGene00000401, cdh-9, CaDHerin family, [RH, Score=82.8, Expect=3e-16]} {Smed: dd_Smed_v6_14410_0_1, dd_Smed_v6_14410_0_1, [Score=78.2, Expect=9e-15]} {RNA1509_57757, RNA1509_6574} {RNA1310_7530, RNA1509_57757} {RNA1509_57757, RNA815_2409} |
7. | MligTC455_39886 | 130 | 2.71 | Mlig455_018360 | Neo: - Age: - Region-enriched R2: 4.560/0.00239 |
1.757 | - | - | 0.779 | 0.978 | - | - | Mlig455_018360 {REF} {Length: 2293} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=79.2]; GDP-mannose 4,6 dehydratase [PF16363.7, score=55.7]; RmlD substrate binding domain [PF04321.19, score=35.8]; Male sterility protein [PF07993.14, score=33.5]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=25.1]; Polysaccharide biosynthesis protein [PF02719.17, score=21.6]} {Mouse: ENSMUSG00000021953, Tdh, L-threonine dehydrogenase, [RH, Score=414, Expect=1e-143]} {Dmel: FBgn0036997, CG5955, [RH, Score=444, Expect=5e-156]} {Celegans: WBGene00017262, F08F3.4, [RH, Score=340, Expect=3e-115]} {Smed: dd_Smed_v6_12075_0_1, dd_Smed_v6_12075_0_1, [RH, Score=444, Expect=7e-157]} {RNA1509_44687} {RNA1310_15323} {RNA815_7207.1} | |
8. | MligTC455_45817 | 492 | 10.24 | Mlig455_004593, Mlig455_064772 | Neo: - Age: - |
RRAD | 1.757 | 0.778 | - | - | - | - | 0.979 | Mlig455_004593 {REF} {Length: 2289} {Pfam: Ras family [PF00071.24, score=69.4]; RsgA GTPase [PF03193.18, score=22.0]; ADP-ribosylation factor family [PF00025.23, score=20.1]} {Human: ENSG00000166592, RRAD, RRAD, Ras related glycolysis inhibitor and calcium channel regulator, [Score=81.3, Expect=6e-18]; ENSG00000164949, GEM, GTP binding protein overexpressed in skeletal muscle, [Score=78.6, Expect=4e-17]; ENSG00000139890, REM2, RRAD and GEM like GTPase 2, [Score=78.2, Expect=8e-17]} {Mouse: ENSMUSG00000031880, Rrad, Ras-related associated with diabetes, [Score=80.5, Expect=8e-18]; ENSMUSG00000028214, Gem, GTP binding protein (gene overexpressed in skeletal muscle), [Score=77.8, Expect=7e-17]; ENSMUSG00000022176, Rem2, rad and gem related GTP binding protein 2, [Score=77.8, Expect=8e-17]} {Dmel: FBgn0264753, Rgk1, Rad, Gem/Kir family member 1, [Score=107, Expect=3e-27]} {Celegans: WBGene00013124, Y52B11A.4, [Score=60.1, Expect=9e-11]} {Smed: dd_Smed_v6_11010_0_1, dd_Smed_v6_11010_0_1, [Score=130, Expect=3e-36]} {RNA1509_20692} {RNA1310_28257.1} {RNA815_21843} Mlig455_064772 {REF} {Length: 4499} {Pfam: Ras family [PF00071.24, score=78.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=27.1]; ADP-ribosylation factor family [PF00025.23, score=23.3]; RsgA GTPase [PF03193.18, score=21.6]} {Human: ENSG00000166592, RRAD, RRAD, Ras related glycolysis inhibitor and calcium channel regulator, [Score=91.3, Expect=1e-19]; ENSG00000164949, GEM, GTP binding protein overexpressed in skeletal muscle, [Score=88.6, Expect=8e-19]} {Mouse: ENSMUSG00000031880, Rrad, Ras-related associated with diabetes, [Score=93.2, Expect=2e-20]} {Dmel: FBgn0264753, Rgk1, Rad, Gem/Kir family member 1, [RH, Score=137, Expect=8e-34]} {Celegans: WBGene00010038, rheb-1, GTP-binding protein Rheb homolog 1, [Score=73.9, Expect=6e-15]} {Smed: dd_Smed_v6_11010_0_1, dd_Smed_v6_11010_0_1, [RH, Score=170, Expect=2e-47]} {RNA1509_15087, RNA1509_20692, RNA1509_37785} {RNA1310_15968.2, RNA1509_15087, RNA1509_20692} {RNA1509_15087, RNA1509_20692, RNA815_18047} |
9. | MligTC455_37360 | 5178 | 107.87 | Mlig455_043000 | Neo: - |
CFAP52 | 1.747 | - | - | 0.797 | 0.950 | - | - | Mlig455_043000 {REF} {Length: 2520} {Pfam: WD domain, G-beta repeat [PF00400.34, score=124.0]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=41.8]; WD40-like domain [PF17005.7, score=26.5]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=748, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=756, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=439, Expect=3e-145]} {Celegans: WBGene00022119, copa-1, Coatomer subunit alpha, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=838, Expect=0.0]} {RNA1509_1341} {RNA1310_8859} {RNA815_2855} |
10. | MligTC455_39315 | 215 | 4.48 | Mlig455_002260 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-0.448 Region-enriched R2: 2.806/0.02025 |
CFAP99 | 1.742 | - | - | - | 0.958 | - | 0.784 | Mlig455_002260 {REF} {Length: 3233} {Human: ENSG00000206113, CFAP99, cilia and flagella associated protein 99, [Score=187, Expect=8e-52]} {Mouse: ENSMUSG00000109572, Cfap99, cilia and flagella associated protein 99, [Score=201, Expect=2e-57]} {Smed: dd_Smed_v6_8538_0_1, dd_Smed_v6_8538_0_1, [Score=203, Expect=1e-58]} {RNA1509_10540} {RNA1310_6581} {RNA815_2531} |
11. | MligTC455_40522 | 114 | 2.38 | Mlig455_047004, Mlig455_047037 | Neo: - |
ANGPTL3 | 1.724 | - | - | - | 0.981 | - | 0.743 | Mlig455_047004 {REF} {Length: 1341} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=62.5]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=57.0, Expect=8e-09]} {Mouse: ENSMUSG00000022309, Angpt1, angiopoietin 1, [Score=52.0, Expect=2e-07]} {Dmel: FBgn0031804, CG9500, [Score=71.2, Expect=2e-14]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=50.1, Expect=6e-07]} {RNA1509_53291} {RNA1310_30694.1} {RNA815_9881} Mlig455_047037 {REF} {Length: 1945} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=60.2]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=58.9, Expect=8e-09]} {Mouse: ENSMUSG00000022309, Angpt1, angiopoietin 1, [Score=53.1, Expect=4e-07]} {Dmel: FBgn0031804, CG9500, [Score=72.8, Expect=4e-14]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=53.5, Expect=1e-07]} {RNA1509_53291} {RNA1310_30694.1} {RNA815_9881} |
12. | MligTC455_44443 | 3132 | 65.25 | Mlig455_062757 | Neo: - Age: Up-Down-Down |
1.703 | - | - | 0.748 | 0.955 | - | - | Mlig455_062757 {REF} {Length: 897} {RNA1509_42258} {RNA1310_10649.1} {RNA815_4791.1} | |
13. | MligTC455_37149 | 33 | 0.69 | Mlig455_029430 | Neo: - Age: - Region-enriched R6: 4.379/0.04065 |
MYL4 | 1.679 | - | - | 0.712 | 0.967 | - | - | Mlig455_029430 {REF} {Length: 841} {Pfam: EF-hand domain pair [PF13499.8, score=40.9]; EF hand [PF00036.34, score=25.2]; EF-hand domain pair [PF13833.8, score=24.8]; EF-hand domain [PF13405.8, score=22.4]} {Human: ENSG00000198336, MYL4, myosin light chain 4, [Score=56.2, Expect=2e-09]; ENSG00000101335, MYL9, myosin light chain 9, [Score=53.9, Expect=9e-09]; ENSG00000160808, MYL3, myosin light chain 3, [Score=53.9, Expect=1e-08]} {Mouse: ENSMUSG00000059741, Myl3, myosin, light polypeptide 3, [Score=56.6, Expect=1e-09]; ENSMUSG00000061086, Myl4, myosin, light polypeptide 4, [Score=55.5, Expect=2e-09]} {Dmel: FBgn0004687, Mlc-c, Myosin light chain cytoplasmic, [Score=68.9, Expect=9e-15]} {Celegans: WBGene00011734, mlc-5, Myosin-2 essential light chain, [Score=62.0, Expect=2e-12]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=48.5, Expect=7e-07]} {RNA1509_43205} {RNA1310_45370} {RNA815_24120.1} |
14. | MligTC455_45919 | 242 | 5.04 | Mlig455_040207 | Neo: - Age: - |
PLSCR1 | 1.662 | 0.700 | - | - | - | - | 0.962 | Mlig455_040207 {REF} {Length: 2652} {Pfam: Scramblase [PF03803.17, score=245.9]} {Human: ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=241, Expect=1e-77]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=231, Expect=8e-74]; ENSMUSG00000032372, Plscr2, phospholipid scramblase 2, [Score=227, Expect=2e-72]} {Dmel: FBgn0052056, scramb1, scramblase 1, [RH, Score=241, Expect=2e-76]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=191, Expect=3e-59]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [RH, Score=297, Expect=6e-100]} {RNA1509_25839} {RNA1310_11207.1} {RNA815_13677} |
15. | MligTC455_00873 | 4331 | 90.22 | Mlig455_021477 | Neo: - Age: Down-Down-Up |
0.993 | - | - | - | 0.993 | - | - | Mlig455_021477 {REF} {Length: 796} {RNA1509_1530} {RNA1310_43551.1} {RNA815_23356} | |
16. | MligTC455_00874 | 13475 | 280.72 | Mlig455_062026, Mlig455_063227, Mlig455_067362 | Neo: - |
0.993 | - | - | - | 0.993 | - | - | Mlig455_062026 {REF} {Length: 845} {RNA1509_1530} {RNA1310_43551.1} {RNA815_23356} Mlig455_063227 {REF} {Length: 1882} {RNA1509_1530, RNA1509_170, RNA1509_6079} {RNA1310_43551.1, RNA1509_1530, RNA1509_170, RNA1509_6079} {RNA1509_1530, RNA1509_170, RNA1509_6079, RNA815_23356} Mlig455_067362 {REF} {Length: 909} {RNA1509_1530} {RNA1310_43551.1} {RNA815_23356} |
|
17. | MligTC455_28563 | 196 | 4.09 | Mlig455_061802 | Neo: - Age: Up-Down-Down Region-enriched R8: 4.606/0.00003 |
KCNJ12 | 0.986 | - | - | - | 0.986 | - | - | Mlig455_061802 {REF} {Length: 5059} {Pfam: Inward rectifier potassium channel C-terminal domain [PF17655.3, score=194.7]; Inward rectifier potassium channel transmembrane domain [PF01007.22, score=168.7]} {Human: ENSG00000184185, KCNJ12, potassium voltage-gated channel subfamily J member 12, [Score=315, Expect=3e-104]; ENSG00000260458, KCNJ18, potassium voltage-gated channel subfamily J member 18, [Score=311, Expect=8e-103]; ENSG00000123700, KCNJ2, potassium voltage-gated channel subfamily J member 2, [Score=300, Expect=1e-98]} {Mouse: ENSMUSG00000042529, Kcnj12, potassium inwardly-rectifying channel, subfamily J, member 12, [Score=316, Expect=6e-105]; ENSMUSG00000044216, Kcnj4, potassium inwardly-rectifying channel, subfamily J, member 4, [Score=301, Expect=6e-99]} {Dmel: FBgn0265042, Irk1, Inwardly rectifying potassium channel 1, [Score=311, Expect=9e-102]} {Celegans: WBGene00002150, irk-2, Inward Rectifying K (Potassium) channel family, [Score=296, Expect=4e-97]} {RNA1509_57087} {RNA1310_22528, RNA1509_57087} {RNA1509_57087, RNA815_8424.1} |
18. | MligTC455_28564 | 383 | 7.97 | Mlig455_010532, Mlig455_061843 | Neo: - Age: - Region-enriched R8: 4.824/0.00000 |
KCNJ12 | 0.984 | - | - | - | 0.984 | - | - | Mlig455_010532 {REF} {Length: 1728} {Pfam: Inward rectifier potassium channel C-terminal domain [PF17655.3, score=178.4]; Inward rectifier potassium channel transmembrane domain [PF01007.22, score=147.1]} {Human: ENSG00000184185, KCNJ12, potassium voltage-gated channel subfamily J member 12, [Score=260, Expect=1e-83]; ENSG00000260458, KCNJ18, potassium voltage-gated channel subfamily J member 18, [Score=256, Expect=4e-82]} {Mouse: ENSMUSG00000042529, Kcnj12, potassium inwardly-rectifying channel, subfamily J, member 12, [Score=261, Expect=3e-84]; ENSMUSG00000044216, Kcnj4, potassium inwardly-rectifying channel, subfamily J, member 4, [Score=251, Expect=7e-80]} {Dmel: FBgn0265042, Irk1, Inwardly rectifying potassium channel 1, [Score=256, Expect=2e-81]} {Celegans: WBGene00002150, irk-2, Inward Rectifying K (Potassium) channel family, [Score=246, Expect=5e-78]} {RNA1509_57087} {RNA1310_22528} {RNA815_8424.1} Mlig455_061843 {REF} {Length: 1636} {Pfam: Inward rectifier potassium channel C-terminal domain [PF17655.3, score=194.7]; Inward rectifier potassium channel transmembrane domain [PF01007.22, score=167.7]} {Human: ENSG00000184185, KCNJ12, potassium voltage-gated channel subfamily J member 12, [Score=314, Expect=6e-104]; ENSG00000260458, KCNJ18, potassium voltage-gated channel subfamily J member 18, [Score=311, Expect=1e-102]} {Mouse: ENSMUSG00000042529, Kcnj12, potassium inwardly-rectifying channel, subfamily J, member 12, [Score=315, Expect=1e-104]; ENSMUSG00000044216, Kcnj4, potassium inwardly-rectifying channel, subfamily J, member 4, [Score=301, Expect=1e-98]} {Dmel: FBgn0265042, Irk1, Inwardly rectifying potassium channel 1, [Score=310, Expect=2e-101]} {Celegans: WBGene00002150, irk-2, Inward Rectifying K (Potassium) channel family, [Score=297, Expect=3e-97]} {RNA1509_57087} {RNA1310_22528} {RNA815_8424.1} |
19. | MligTC455_20104 | 6823 | 142.15 | Mlig455_005122, Mlig455_005188 | Neo: - Age: Down-Down-Up Region-enriched R8: 2.180/0.00000 Regeneration-downregulated BL: -1.991 Regeneration-depleted BL: -1.991 |
0.975 | - | - | - | 0.975 | - | - | Mlig455_005122 {REF} {Length: 718} {TRANSSPLICED} {RNA1509_9059} {RNA1310_66949} {RNA815_34214} Mlig455_005188 {REF} {Length: 1433} {RNA1509_25823, RNA1509_9059} {RNA1310_66949, RNA1509_25823, RNA1509_9059} {RNA1509_25823, RNA1509_9059, RNA815_34214} |
|
20. | MligTC455_46122 | 188 | 3.92 | Mlig455_040096 | Neo: - |
ADAM9 | 0.973 | - | - | - | 0.973 | - | - | Mlig455_040096 {REF} {Length: 3561} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=164.8]; Metallo-peptidase family M12 [PF13688.8, score=74.4]; Disintegrin [PF00200.25, score=72.2]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=60.7]; ADAM cysteine-rich [PF08516.14, score=52.2]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=50.0]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=42.0]; Reprolysin family propeptide [PF01562.21, score=19.8]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [RH, Score=270, Expect=9e-77]; ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [RH, Score=268, Expect=1e-75]; ENSG00000135074, ADAM19, ADAM metallopeptidase domain 19, [RH, Score=267, Expect=1e-74]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [RH, Score=263, Expect=4e-74]; ENSG00000143537, ADAM15, ADAM metallopeptidase domain 15, [RH, Score=263, Expect=8e-74]; ENSG00000042980, ADAM28, ADAM metallopeptidase domain 28, [RH, Score=262, Expect=3e-74]} {Mouse: ENSMUSG00000025473, Adam8, a disintegrin and metallopeptidase domain 8, [RH, Score=283, Expect=1e-81]; ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [RH, Score=273, Expect=4e-78]} {Dmel: FBgn0265140, Meltrin, [RH, Score=301, Expect=4e-85]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [RH, Score=256, Expect=1e-71]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=248, Expect=3e-68]} {RNA1509_3757, RNA1509_6969} {RNA1310_8106.1, RNA1509_6969} {RNA1509_6969, RNA815_6893} |
21. | MligTC455_24891 | 845 | 17.6 | Mlig455_016464 | Neo: - |
0.971 | - | - | - | 0.971 | - | - | Mlig455_016464 {REF} {Length: 2447} {RNA1509_20271, RNA1509_46463} {RNA1310_10597.1, RNA1509_20271, RNA1509_46463} {RNA1509_20271, RNA1509_46463, RNA815_3690.1} | |
22. | MligTC455_06164 | 106 | 2.2 | Mlig455_052245 | Neo: - Age: logFC(26M/2M)=-0.637 Region-enriched R2: 3.704/0.01603 |
0.969 | - | - | - | 0.969 | - | - | Mlig455_052245 {REF} {Length: 2662} {Pfam: Otopetrin [PF03189.15, score=32.9]} {RNA1509_13057} {RNA1310_7247, RNA1509_13057} {RNA1509_13057, RNA815_2303} | |
23. | MligTC455_08224 | 46 | 0.96 | Mlig455_070576 | Neo: - Age: logFC(26M/2M)=-0.522 |
0.968 | - | - | - | 0.968 | - | - | Mlig455_070576 {REF} {Length: 1598} {Pfam: ZIP Zinc transporter [PF02535.24, score=22.5]; V-type ATPase 116kDa subunit family [PF01496.21, score=16.8]} {RNA1509_23198} {RNA1310_21075.2} {RNA815_20720.2} | |
24. | MligTC455_29515 | 2468 | 51.42 | Mlig455_043789 | Neo: - |
0.968 | - | - | - | 0.968 | - | - | Mlig455_043789 {REF} {Length: 1818} {NoTransDecoderORF} {RNA1509_30770, RNA1509_31776, RNA1509_32411, RNA1509_33231, RNA1509_3537, RNA1509_58526} {RNA1310_7321.1, RNA1509_30770, RNA1509_31776, RNA1509_32411, RNA1509_33231, RNA1509_3537, RNA1509_58526} {RNA1509_30770, RNA1509_31776, RNA1509_32411, RNA1509_33231, RNA1509_3537, RNA1509_58526, RNA815_4667} | |
25. | MligTC455_33860 | 384 | 8.01 | Mlig455_024990, Mlig455_025004 | Neo: - Age: Down-Down-Down, logFC(26M/2M)=-1.340 Region-enriched R2: 4.294/0.00006 |
0.967 | - | - | - | 0.967 | - | - | Mlig455_024990 {REF} {Length: 1540} {RNA1509_36587} {RNA1310_35553} {RNA815_21400} Mlig455_025004 {REF} {Length: 1546} {RNA1509_36587} {RNA1310_35553} {RNA815_21400} |
|
26. | MligTC455_44177 | 70 | 1.46 | Mlig455_022828, Mlig455_022920 | Neo: - Age: - |
TNKS | 0.965 | - | - | - | 0.965 | - | - | Mlig455_022828 {REF} {Length: 1654} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=58.3]; Ankyrin repeats (many copies) [PF13637.8, score=51.4]; Ankyrin repeats (many copies) [PF13857.8, score=43.5]; Ankyrin repeat [PF00023.32, score=38.9]; Ankyrin repeat [PF13606.8, score=35.6]} {Dmel: FBgn0039955, CG41099, [Score=56.6, Expect=5e-08]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=53.1, Expect=4e-07]} {Smed: dd_Smed_v6_11252_0_1, dd_Smed_v6_11252_0_1, [Score=50.8, Expect=1e-06]} {RNA1509_39040} {RNA1310_886.1} {RNA815_14632} Mlig455_022920 {REF} {Length: 1424} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=65.4]; Ankyrin repeats (3 copies) [PF12796.9, score=61.1]; Ankyrin repeats (many copies) [PF13857.8, score=57.9]; Ankyrin repeat [PF13606.8, score=50.1]; Ankyrin repeat [PF00023.32, score=49.7]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=56.2, Expect=9e-08]; ENSG00000236759, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000238134, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000285372, AC270292.3, tankyrase, [Score=55.5, Expect=2e-07]; ENSG00000232045, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000206376, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000227333, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000204371, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000224143, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=54.3, Expect=3e-07]; ENSG00000029534, ANK1, ankyrin 1, [Score=53.5, Expect=8e-07]} {Mouse: ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=56.6, Expect=3e-08]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=56.6, Expect=3e-08]; ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=56.2, Expect=3e-08]; ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=56.2, Expect=6e-08]; ENSMUSG00000013787, Ehmt2, euchromatic histone lysine N-methyltransferase 2, [Score=55.1, Expect=2e-07]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=55.1, Expect=2e-07]; ENSMUSG00000110591, Gm31371, predicted gene, 31371, [Score=54.3, Expect=8e-08]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=53.9, Expect=2e-07]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=53.9, Expect=2e-07]} {Dmel: FBgn0040752, Prosap, [Score=58.5, Expect=1e-08]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=51.6, Expect=9e-07]} {Smed: dd_Smed_v6_2072_0_20, dd_Smed_v6_2072_0_20, [Score=59.3, Expect=3e-09]} {RNA1509_39040} {RNA1310_19494} {RNA815_14632} |
27. | MligTC455_44937 | 112 | 2.33 | Mlig455_058569 | Neo: - Age: Down-Up-Down |
0.965 | - | - | - | 0.965 | - | - | Mlig455_058569 {REF} {Length: 1225} {Dmel: FBgn0034289, CG10910, [Score=95.9, Expect=4e-22]} {RNA1509_30568} {RNA1310_70061} {RNA815_48492} | |
28. | MligTC455_21523 | 317 | 6.61 | Mlig455_029394 | Neo: - Age: - Region-enriched R6: 2.246/0.01608 Regeneration-downregulated R6: -3.517 Regeneration-depleted R6: -3.517 |
MYL4 | 0.964 | - | - | - | 0.964 | - | - | Mlig455_029394 {REF} {Length: 861} {Pfam: EF-hand domain pair [PF13499.8, score=40.0]; EF hand [PF00036.34, score=25.2]; EF-hand domain pair [PF13833.8, score=24.8]; EF-hand domain [PF13405.8, score=22.4]} {Human: ENSG00000198336, MYL4, myosin light chain 4, [Score=57.4, Expect=7e-10]; ENSG00000160808, MYL3, myosin light chain 3, [Score=55.5, Expect=4e-09]} {Mouse: ENSMUSG00000059741, Myl3, myosin, light polypeptide 3, [Score=57.4, Expect=5e-10]; ENSMUSG00000061086, Myl4, myosin, light polypeptide 4, [Score=56.6, Expect=7e-10]} {Dmel: FBgn0004687, Mlc-c, Myosin light chain cytoplasmic, [Score=70.1, Expect=3e-15]} {Celegans: WBGene00011734, mlc-5, Myosin-2 essential light chain, [Score=61.6, Expect=3e-12]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=48.5, Expect=6e-07]} {RNA1509_43205} {RNA1310_45370, RNA1509_43205} {RNA1509_43205, RNA815_24120.1} |
29. | MligTC455_26358 | 428 | 8.93 | Mlig455_012675 | Neo: - Age: logFC(26M/2M)=-0.338 Region-enriched R2: 1.608/0.04280 |
NOTCH2 | 0.964 | - | - | - | 0.964 | - | - | Mlig455_012675 {REF} {Length: 4700} {Pfam: EGF-like domain [PF00008.29, score=144.8]; Ankyrin repeats (3 copies) [PF12796.9, score=86.3]; Human growth factor-like EGF [PF12661.9, score=80.1]; Ankyrin repeats (many copies) [PF13857.8, score=70.9]; Ankyrin repeat [PF00023.32, score=65.4]; Ankyrin repeats (many copies) [PF13637.8, score=61.9]; Ankyrin repeat [PF13606.8, score=58.6]; LNR domain [PF00066.19, score=52.0]; EGF-like domain [PF07974.15, score=46.9]; Calcium-binding EGF domain [PF07645.17, score=31.9]} {Human: ENSG00000134250, NOTCH2, notch 2, [Score=311, Expect=2e-87]} {Mouse: ENSMUSG00000027878, Notch2, notch 2, [Score=329, Expect=2e-93]} {Dmel: FBgn0004647, N, Notch, [Score=325, Expect=6e-92]} {Celegans: WBGene00003001, lin-12, [Score=242, Expect=2e-65]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=214, Expect=1e-56]} {RNA1509_20447, RNA1509_55795} {RNA1310_1718.1, RNA1509_20447, RNA1509_55795} {RNA1509_20447, RNA1509_55795, RNA815_12429} |
30. | MligTC455_46121 | 383 | 7.98 | Mlig455_040070 | Neo: - Age: Down-Down-Down, logFC(26M/2M)=-1.053 Region-enriched R8: 1.848/0.03941 Regeneration-depleted BL: -3.853 |
ADAM15 | 0.962 | - | - | - | 0.962 | - | - | Mlig455_040070 {REF} {Length: 3347} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=95.1]; Disintegrin [PF00200.25, score=73.2]; ADAM cysteine-rich [PF08516.14, score=53.8]; Metallo-peptidase family M12 [PF13688.8, score=43.1]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=39.8]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=34.6]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=30.8]} {Human: ENSG00000143537, ADAM15, ADAM metallopeptidase domain 15, [Score=208, Expect=6e-58]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=208, Expect=8e-58]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [Score=206, Expect=5e-57]; ENSG00000135074, ADAM19, ADAM metallopeptidase domain 19, [Score=200, Expect=1e-54]} {Mouse: ENSMUSG00000025473, Adam8, a disintegrin and metallopeptidase domain 8, [Score=214, Expect=7e-60]; ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [Score=211, Expect=5e-59]; ENSMUSG00000028041, Adam15, a disintegrin and metallopeptidase domain 15 (metargidin), [Score=210, Expect=2e-58]; ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=210, Expect=9e-59]} {Dmel: FBgn0265140, Meltrin, [Score=258, Expect=2e-75]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=205, Expect=1e-56]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=211, Expect=9e-59]} {RNA1509_45097} {RNA1310_8106.1} {RNA815_6893} |
31. | MligTC455_12483 | 119 | 2.48 | Mlig455_054794 | Neo: - Age: Up-Down-Down |
FBN1 | 0.961 | - | - | - | - | - | 0.961 | Mlig455_054794 {REF} {Length: 4896} {Pfam: Calcium-binding EGF domain [PF07645.17, score=32.9]; Complement Clr-like EGF-like [PF12662.9, score=32.7]; von Willebrand factor type D domain [PF00094.27, score=27.7]} {Human: ENSG00000166147, FBN1, fibrillin 1, [Score=81.3, Expect=5e-15]; ENSG00000142449, FBN3, fibrillin 3, [Score=79.3, Expect=2e-14]} {Mouse: ENSMUSG00000027204, Fbn1, fibrillin 1, [Score=79.0, Expect=2e-14]} {Dmel: FBgn0051999, CG31999, [Score=60.1, Expect=6e-09]} {Celegans: WBGene00001403, fbl-1, Fibulin-1, [Score=61.2, Expect=2e-09]} {Smed: dd_Smed_v6_7311_0_1, dd_Smed_v6_7311_0_1, [Score=65.1, Expect=1e-10]} {RNA1509_35545, RNA1509_46557, RNA1509_6367} {RNA1310_702.1, RNA1509_35545, RNA1509_46557, RNA1509_6367} {RNA1509_35545, RNA1509_46557, RNA1509_6367, RNA815_201.1} |
32. | MligTC455_29513 | 212 | 4.41 | Mlig455_012936 | Neo: - Age: - Region-enriched R4: 3.989/0.00404 |
0.961 | - | - | - | 0.961 | - | - | Mlig455_012936 {REF} {Length: 1620} {NoTransDecoderORF} {RNA1509_31776} {RNA1310_7321.1} {RNA815_4667} | |
33. | MligTC455_18586 | 93 | 1.93 | Mlig455_020226 | Neo: - Age: Down-Down-Up |
0.958 | - | - | - | 0.958 | - | - | Mlig455_020226 {REF} {Length: 1261} {RNA1310_64121} {RNA815_32233} | |
34. | MligTC455_42188 | 714 | 14.88 | Mlig455_004983 | Neo: - Age: - |
0.956 | - | - | - | 0.956 | - | - | Mlig455_004983 {REF} {Length: 958} {RNA1509_36666, RNA1509_48333} {RNA1310_81420, RNA1509_36666, RNA1509_48333} {RNA1509_36666, RNA1509_48333, RNA815_25950} | |
35. | MligTC455_23309 | 257 | 5.35 | Mlig455_013628 | Neo: - Age: Up-Down-Up |
0.955 | - | - | - | - | - | 0.955 | Mlig455_013628 {REF} {Length: 1039} {RNA1509_48616} {RNA1310_6959, RNA1509_48616} {RNA1509_48616, RNA815_10949} | |
36. | MligTC455_48011 | 321 | 6.68 | Mlig455_053119 | Neo: - Age: logFC(26M/2M)=-0.341 |
0.954 | - | - | - | - | - | 0.954 | Mlig455_053119 {REF} {Length: 938} {Smed: dd_Smed_v6_2217_0_1, dd_Smed_v6_2217_0_1, [RH, Score=54.7, Expect=4e-10]} {RNA1509_30673} {RNA1310_38150, RNA1509_30673} {RNA1509_30673, RNA815_20383} | |
37. | MligTC455_14903 | 1751 | 36.49 | Mlig455_037514 | Neo: - Age: - Region-enriched R8: 1.893/0.00470 |
0.953 | - | - | - | 0.953 | - | - | Mlig455_037514 {REF} {Length: 2886} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=58.5, Expect=6e-09]} {Celegans: WBGene00008194, C49C3.4, [Score=51.2, Expect=1e-06]} {RNA1509_4337} {RNA1310_7259} {RNA815_206} | |
38. | MligTC455_44963 | 18 | 0.38 | Mlig455_070386 | Neo: - Age: - |
0.952 | - | - | - | - | - | 0.952 | Mlig455_070386 {REF} {Length: 1852} {Pfam: Glycine rich protein [PF12810.9, score=22.8]} {RNA1310_33363.2} {RNA815_25152} | |
39. | MligTC455_20421 | 31 | 0.65 | Mlig455_010709 | Neo: - Age: - Region-enriched R7: 3.787/0.04771 |
0.951 | - | - | 0.951 | - | - | - | Mlig455_010709 {REF} {Length: 2034} {RNA1310_48353} | |
40. | MligTC455_38366 | 13 | 0.26 | Mlig455_061003 | Neo: - Age: - |
0.951 | - | - | - | 0.951 | - | - | Mlig455_061003 {REF} {Length: 3813} {RNA1509_45293} {RNA1310_91136} {RNA815_26499} | |
41. | MligTC455_12277 | 22 | 0.46 | Mlig455_025521 | Neo: - Age: Down-Up-Down |
CASP3 | 0.95 | - | - | - | - | - | 0.950 | Mlig455_025521 {REF} {Length: 4174} {Pfam: Protein kinase domain [PF00069.27, score=194.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=181.9]; Caspase domain [PF00656.24, score=110.6]} {Human: ENSG00000164305, CASP3, caspase 3, [Score=135, Expect=8e-35]; ENSG00000138794, CASP6, caspase 6, [Score=129, Expect=2e-32]} {Mouse: ENSMUSG00000031628, Casp3, caspase 3, [Score=132, Expect=6e-34]; ENSMUSG00000028914, Casp9, caspase 9, [Score=129, Expect=4e-31]} {Dmel: FBgn0010501, Dcp-1, Death caspase-1, [Score=113, Expect=5e-27]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10708_0_1, dd_Smed_v6_10708_0_1, [RH, Score=124, Expect=4e-30]} {RNA1509_16483} {RNA1310_10829} {RNA815_3681.1} |
42. | MligTC455_51033 | 856 | 17.82 | Mlig455_019680 | Neo: - Age: Down-Down-Up, logFC(26M/2M)=-0.458 Region-enriched R8: 3.523/0.00000 |
CAV1 | 0.95 | - | - | - | 0.950 | - | - | Mlig455_019680 {REF} {Length: 1224} {Pfam: Caveolin [PF01146.19, score=118.7]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=102, Expect=5e-27]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=103, Expect=1e-27]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=79.0, Expect=1e-17]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=142, Expect=1e-43]} {RNA1509_58612} {RNA1310_36937.1} {RNA815_17384.1} |
43. | MligTC455_51186 | 86 | 1.79 | Mlig455_012864 | Neo: - Age: Up-Down-Down |
CLCN1 | 0.95 | - | - | 0.950 | - | - | - | Mlig455_012864 {REF} {Length: 4861} {Pfam: Voltage gated chloride channel [PF00654.22, score=186.4]} {Human: ENSG00000188037, CLCN1, chloride voltage-gated channel 1, [Score=179, Expect=1e-45]} {Mouse: ENSMUSG00000029862, Clcn1, chloride channel, voltage-sensitive 1, [Score=175, Expect=2e-44]} {Dmel: FBgn0051116, ClC-a, Chloride channel-a, [Score=167, Expect=6e-42]} {Celegans: WBGene00000530, clh-3, Chloride channel protein clh-3, [Score=209, Expect=3e-55]} {Smed: dd_Smed_v6_12606_0_1, dd_Smed_v6_12606_0_1, [RH, Score=181, Expect=7e-47]} {RNA1310_30491} {RNA815_34327} |