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Results for MligTC455_30287

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_30287 58 1.21 Mlig455_047054

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.661

Region-enriched R4: 5.589/0.02506

MAP3K6 Mlig455_047054 {REF} {Length: 3219} {Pfam: Protein kinase domain [PF00069.27, score=161.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=119.7]; Ankyrin repeats (3 copies) [PF12796.9, score=70.4]; Ankyrin repeats (many copies) [PF13857.8, score=47.2]; Ankyrin repeats (many copies) [PF13637.8, score=44.2]; Ankyrin repeat [PF13606.8, score=40.0]; Ankyrin repeat [PF00023.32, score=34.7]; Fungal protein kinase [PF17667.3, score=24.3]; Phosphotransferase enzyme family [PF01636.25, score=20.2]} {Human: ENSG00000142733, MAP3K6, mitogen-activated protein kinase kinase kinase 6, [Score=130, Expect=2e-30]; ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=127, Expect=2e-29]} {Mouse: ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=133, Expect=1e-31]} {Dmel: FBgn0024329, Mekk1, [Score=128, Expect=4e-30]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=129, Expect=2e-30]} {Smed: dd_Smed_v6_4849_0_1, dd_Smed_v6_4849_0_1, [Score=113, Expect=1e-25]} {RNA1509_27731} {RNA1310_10050} {RNA815_9449.1}

Cumulative graph for MligTC455_30287

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.522 1.592 0.99959 1.00000
RegionR2 -2.209 1.592 0.95851 1.00000
RegionR3 -2.525 1.592 1.00000 1.00000
RegionR4 5.589 1.592 0.00310 0.02506
RegionR5 2.546 1.592 0.05369 0.19729
RegionR6 1.346 1.592 0.34197 0.92878
RegionR7 -2.385 1.592 0.99964 1.00000
RegionR8 -0.839 1.592 0.99962 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.139 1.592 1.00000 1.00000
RegenerationR2 1.677 1.592 0.22141 0.66877
RegenerationR3 2.022 1.592 0.24763 0.68172
RegenerationR4 -0.541 1.592 0.56947 0.90112
RegenerationR5 -0.203 1.592 0.71294 0.95690
RegenerationR6 -1.264 1.592 0.26595 0.61586
RegenerationBL 0.938 1.592 0.59684 0.94494
RegenerationTP -2.448 1.592 0.99981 1.00000


Genes with expression patterns similar to MligTC455_30287

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_30287 58 1.21 Mlig455_047054

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.661

Region-enriched R4: 5.589/0.02506

MAP3K6 4 - - 1.000 1.000 1.000 1.000 Mlig455_047054 {REF} {Length: 3219} {Pfam: Protein kinase domain [PF00069.27, score=161.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=119.7]; Ankyrin repeats (3 copies) [PF12796.9, score=70.4]; Ankyrin repeats (many copies) [PF13857.8, score=47.2]; Ankyrin repeats (many copies) [PF13637.8, score=44.2]; Ankyrin repeat [PF13606.8, score=40.0]; Ankyrin repeat [PF00023.32, score=34.7]; Fungal protein kinase [PF17667.3, score=24.3]; Phosphotransferase enzyme family [PF01636.25, score=20.2]} {Human: ENSG00000142733, MAP3K6, mitogen-activated protein kinase kinase kinase 6, [Score=130, Expect=2e-30]; ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=127, Expect=2e-29]} {Mouse: ENSMUSG00000028862, Map3k6, mitogen-activated protein kinase kinase kinase 6, [Score=133, Expect=1e-31]} {Dmel: FBgn0024329, Mekk1, [Score=128, Expect=4e-30]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=129, Expect=2e-30]} {Smed: dd_Smed_v6_4849_0_1, dd_Smed_v6_4849_0_1, [Score=113, Expect=1e-25]} {RNA1509_27731} {RNA1310_10050} {RNA815_9449.1}
2. MligTC455_28070 31 0.65 Mlig455_003961

Neo: -

Age: Up-Down-Down

1.723 - - 0.752 - 0.971 - Mlig455_003961 {REF} {Length: 2138} {NoTransDecoderORF} {RNA1509_25022} {RNA1310_10847.1} {RNA815_23623}
3. MligTC455_25224 37 0.76 Mlig455_008664, Mlig455_041970

Neo: -

Age: Up-Down-Down

0.983 - - - - 0.983 -

Mlig455_008664 {REF} {Length: 5275} {Pfam: Plasmodium histidine-rich protein (HRPII/III) [PF05403.13, score=23.8]} {RNA1509_44743} {RNA1310_5450.1} {RNA815_16253.2}

Mlig455_041970 {REF} {Length: 4204} {Pfam: Plasmodium histidine-rich protein (HRPII/III) [PF05403.13, score=23.8]} {RNA1509_44743} {RNA1310_5450.1} {RNA815_7136.1}
4. MligTC455_38290 222 4.63 Mlig455_045005

Neo: -

Age: -

SOAT1 0.981 - - 0.981 - - - Mlig455_045005 {REF} {Length: 3948} {TRANSSPLICED} {Pfam: MBOAT, membrane-bound O-acyltransferase family [PF03062.21, score=115.6]} {Human: ENSG00000057252, SOAT1, sterol O-acyltransferase 1, [RH, Score=353, Expect=5e-116]} {Mouse: ENSMUSG00000026600, Soat1, sterol O-acyltransferase 1, [RH, Score=359, Expect=2e-118]} {Dmel: FBgn0037612, CG8112, [RH, Score=232, Expect=1e-69]} {Celegans: WBGene00007174, mboa-1, O-acyltransferase, [Score=224, Expect=2e-67]} {Smed: dd_Smed_v6_4278_0_1, dd_Smed_v6_4278_0_1, [RH, Score=390, Expect=5e-131]} {RNA1509_21845} {RNA1310_19155, RNA1509_21845} {RNA1509_21845, RNA815_15179}
5. MligTC455_51661 98 2.04 Mlig455_012017, Mlig455_012480

Neo: -

Age: logFC(26M/2M)=-0.393

CHRM3 0.971 - - - - - 0.971

Mlig455_012017 {REF} {Length: 2227} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=82.5]} {Human: ENSG00000133019, CHRM3, cholinergic receptor muscarinic 3, [Score=64.3, Expect=3e-10]; ENSG00000180720, CHRM4, cholinergic receptor muscarinic 4, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000046159, Chrm3, cholinergic receptor, muscarinic 3, cardiac, [Score=64.3, Expect=2e-10]; ENSMUSG00000074939, Chrm5, cholinergic receptor, muscarinic 5, [Score=63.2, Expect=4e-10]} {Dmel: FBgn0000037, mAChR-A, muscarinic Acetylcholine Receptor, A-type, [Score=70.5, Expect=2e-12]} {Celegans: WBGene00004780, ser-7, SERotonin/octopamine receptor family, [Score=53.5, Expect=2e-07]} {Smed: dd_Smed_v6_20043_0_1, dd_Smed_v6_20043_0_1, [Score=67.4, Expect=8e-12]} {RNA1310_38511.2} {RNA815_15813.1}

Mlig455_012480 {REF} {Length: 1556} {RNA1310_38511.1} {RNA815_15813.1}
6. MligTC455_12376 32 0.68 Mlig455_062734

Neo: -

Age: -

0.968 - - - - 0.968 - Mlig455_062734 {REF} {Length: 61} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_78374}
7. MligTC455_43611 93 1.94 Mlig455_047359, Mlig455_047360

Neo: -

Age: -

0.965 - - - - - 0.965

Mlig455_047359 {REF} {Length: 707} {NoTransDecoderORF} {RNA1310_133647}

Mlig455_047360 {REF} {Length: 911} {NoTransDecoderORF} {RNA1310_133647}
8. MligTC455_34138 10 0.21 Mlig455_035216

Neo: -

Age: -

0.963 - - - - 0.963 - Mlig455_035216 {REF} {Length: 873} {NoTransDecoderORF}
9. MligTC455_00649 13 0.28 Mlig455_014001

Neo: -

Age: -

0.961 - - - - 0.961 - Mlig455_014001 {REF} {Length: 525} {NoTransDecoderORF} {RNA1310_40460}
10. MligTC455_06089 26 0.54 Mlig455_037648

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.770

0.96 - - - - 0.960 - Mlig455_037648 {REF} {Length: 2465} {Pfam: Otopetrin [PF03189.15, score=27.4]} {RNA1509_10108} {RNA1310_12138.2} {RNA815_2847.1}
11. MligTC455_03999 86 1.8 Mlig455_002026, Mlig455_002117, Mlig455_002223

Neo: Germline

Age: -

0.958 - - - - 0.958 -

Mlig455_002026 {REF} {Length: 461} {RNA1310_65306}

Mlig455_002117 {REF} {Length: 461} {RNA1310_65306}

Mlig455_002223 {REF} {Length: 925} {RNA1310_65306} {RNA815_64331}
12. MligTC455_30051 18 0.38 Mlig455_010151

Neo: -

Age: -

0.958 - - - - 0.958 - Mlig455_010151 {REF} {Length: 2317} {Pfam: Integrase zinc binding domain [PF17921.3, score=74.2]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=52.6]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=28.9]; H2C2 zinc finger [PF09337.12, score=27.8]; Integrase core domain [PF00665.28, score=27.0]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=119, Expect=4e-28]} {RNA1509_14295} {RNA1310_1396.1} {RNA815_549.1}
13. MligTC455_29491 238 4.96 Mlig455_069524

Neo: Irradiation

Age: Up-Up-Down, logFC(26M/2M)=0.351

0.956 - - - - 0.956 - Mlig455_069524 {REF} {Length: 3130} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=54.6]; TcdA/TcdB catalytic glycosyltransferase domain [PF12919.9, score=22.8]; Capsular polysaccharide synthesis protein [PF05704.14, score=22.3]} {Smed: dd_Smed_v6_42389_0_1, dd_Smed_v6_42389_0_1, [Score=109, Expect=2e-27]} {RNA1509_17162, RNA1509_41197, RNA1509_54683} {RNA1310_12293.2, RNA1509_17162, RNA1509_41197, RNA1509_54683} {RNA1509_17162, RNA1509_41197, RNA1509_54683, RNA815_9107.2}
14. MligTC455_33612 217 4.51 Mlig455_017362

Neo: -

Age: logFC(26M/2M)=0.818

ASAH2 0.956 - - - - - 0.956 Mlig455_017362 {REF} {Length: 6769} {Pfam: Neutral/alkaline non-lysosomal ceramidase, N-terminal [PF04734.15, score=704.1]; Neutral/alkaline non-lysosomal ceramidase, C-terminal [PF17048.7, score=119.9]; Major Facilitator Superfamily [PF07690.18, score=92.8]} {Human: ENSG00000188611, ASAH2, N-acylsphingosine amidohydrolase 2, [RH, Score=602, Expect=0.0]} {Mouse: ENSMUSG00000024887, Asah2, N-acylsphingosine amidohydrolase 2, [RH, Score=594, Expect=0.0]} {Dmel: FBgn0039774, CDase, Ceramidase, [RH, Score=568, Expect=0.0]} {Celegans: WBGene00011719, T11G6.4, [Score=122, Expect=7e-29]} {Smed: dd_Smed_v6_1726_0_1, dd_Smed_v6_1726_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_25115} {RNA1310_8395.1} {RNA815_2759}
15. MligTC455_49447 105 2.2 Mlig455_027882

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.491

PRKCZ 0.955 - - - - 0.955 - Mlig455_027882 {REF} {Length: 2617} {Pfam: Protein kinase domain [PF00069.27, score=120.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=83.0]; Kinase-like [PF14531.8, score=25.0]} {Human: ENSG00000067606, PRKCZ, protein kinase C zeta, [Score=89.0, Expect=3e-18]; ENSG00000065675, PRKCQ, protein kinase C theta, [Score=88.2, Expect=5e-18]; ENSG00000163558, PRKCI, protein kinase C iota, [Score=88.2, Expect=4e-18]; ENSG00000027075, PRKCH, protein kinase C eta, [Score=87.8, Expect=6e-18]; ENSG00000108443, RPS6KB1, ribosomal protein S6 kinase B1, [Score=87.8, Expect=5e-18]; ENSG00000117676, RPS6KA1, ribosomal protein S6 kinase A1, [Score=86.3, Expect=2e-17]; ENSG00000281877, RPS6KA1, ribosomal protein S6 kinase A1, [Score=86.3, Expect=2e-17]; ENSG00000171132, PRKCE, protein kinase C epsilon, [Score=85.9, Expect=4e-17]} {Mouse: ENSMUSG00000021108, Prkch, protein kinase C, eta, [Score=88.6, Expect=3e-18]; ENSMUSG00000029053, Prkcz, protein kinase C, zeta, [Score=88.2, Expect=3e-18]; ENSMUSG00000037643, Prkci, protein kinase C, iota, [Score=87.8, Expect=4e-18]; ENSMUSG00000020516, Rps6kb1, ribosomal protein S6 kinase, polypeptide 1, [Score=87.4, Expect=5e-18]; ENSMUSG00000025665, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=85.9, Expect=3e-17]; ENSMUSG00000116203, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=85.9, Expect=3e-17]; ENSMUSG00000003644, Rps6ka1, ribosomal protein S6 kinase polypeptide 1, [Score=85.5, Expect=3e-17]; ENSMUSG00000045038, Prkce, protein kinase C, epsilon, [Score=85.1, Expect=5e-17]; ENSMUSG00000026778, Prkcq, protein kinase C, theta, [Score=84.3, Expect=7e-17]; ENSMUSG00000019699, Akt3, thymoma viral proto-oncogene 3, [Score=84.3, Expect=5e-17]} {Dmel: FBgn0003093, Pkc98E, Protein C kinase 98E, [Score=87.0, Expect=6e-18]} {Celegans: WBGene00004032, pkc-1, Protein kinase C-like 1B, [Score=85.1, Expect=2e-17]} {Smed: dd_Smed_v6_8010_0_1, dd_Smed_v6_8010_0_1, [Score=88.6, Expect=1e-18]} {RNA1509_20079, RNA1509_52166} {RNA1310_18713, RNA1509_20079, RNA1509_52166} {RNA1509_20079, RNA1509_52166, RNA815_7871}
16. MligTC455_15536 41 0.86 Mlig455_030649

Neo: -

Age: -

0.953 - - - - 0.953 - Mlig455_030649 {REF} {Length: 1146} {RNA1310_33769.1} {RNA815_16068}
17. MligTC455_06426 14 0.3 Mlig455_045703

Neo: -

Age: -

0.952 - - - - 0.952 - Mlig455_045703 {REF} {Length: 756} {NoTransDecoderORF} {RNA1310_88574} {RNA815_52979}
18. MligTC455_08944 160 3.34 Mlig455_050947

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.619

0.951 - - - - 0.951 - Mlig455_050947 {REF} {Length: 1135} {RNA1310_13460.1} {RNA815_53760}
19. MligTC455_27911 45 0.94 Mlig455_049225, Mlig455_049228

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.777

FAT4 0.951 - - - - 0.951 -

Mlig455_049225 {REF} {Length: 12873} {Pfam: Cadherin domain [PF00028.19, score=824.7]; Cadherin prodomain like [PF08758.13, score=35.4]; Cadherin-like [PF16184.7, score=28.6]; Peptidase propeptide and YPEB domain [PF03413.21, score=22.0]; Bacterial cadherin-like domain [PF17803.3, score=19.8]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=310, Expect=1e-83]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=368, Expect=4e-101]} {Dmel: FBgn0001075, ft, fat, [Score=283, Expect=2e-75]} {Celegans: WBGene00019994, cdh-1, CaDHerin family, [Score=176, Expect=4e-43]} {Smed: dd_Smed_v6_12895_0_1, dd_Smed_v6_12895_0_1, [Score=155, Expect=2e-37]} {RNA1509_562} {RNA1310_5} {RNA815_1}

Mlig455_049228 {REF} {Length: 24107} {Pfam: Cadherin domain [PF00028.19, score=1466.0]; RET Cadherin like domain 1 [PF17756.3, score=58.7]; 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=48.5]; Cadherin-like [PF16184.7, score=34.1]; Cadherin prodomain like [PF08758.13, score=29.5]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=396, Expect=8e-109]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=389, Expect=5e-107]} {Dmel: FBgn0001075, ft, fat, [Score=334, Expect=1e-90]} {Celegans: WBGene00019994, cdh-1, CaDHerin family, [Score=183, Expect=5e-45]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=158, Expect=1e-37]} {RNA1509_562} {RNA1310_5} {RNA815_1}
20. MligTC455_47843 349 7.27 Mlig455_040270, Mlig455_040278

Neo: -

Age: -

RPGRIP1L 0.951 - - - - 0.951 -

Mlig455_040270 {REF} {Length: 4583} {TRANSSPLICED} {Pfam: Retinitis pigmentosa G-protein regulator interacting C-terminal [PF18111.3, score=54.6]} {Human: ENSG00000103494, RPGRIP1L, RPGRIP1 like, [Score=86.7, Expect=2e-16]} {Mouse: ENSMUSG00000033282, Rpgrip1l, Rpgrip1-like, [Score=85.5, Expect=3e-16]} {Celegans: WBGene00015646, mlt-10, [Score=53.1, Expect=1e-06]} {Smed: dd_Smed_v6_11425_0_1, dd_Smed_v6_11425_0_1, [Score=90.1, Expect=4e-18]} {RNA1509_12953} {RNA1310_4375.1} {RNA815_1280}

Mlig455_040278 {REF} {Length: 4279} {TRANSSPLICED} {Pfam: Retinitis pigmentosa G-protein regulator interacting C-terminal [PF18111.3, score=54.9]} {Human: ENSG00000103494, RPGRIP1L, RPGRIP1 like, [Score=129, Expect=8e-30]} {Mouse: ENSMUSG00000033282, Rpgrip1l, Rpgrip1-like, [Score=126, Expect=5e-29]} {Smed: dd_Smed_v6_11425_0_1, dd_Smed_v6_11425_0_1, [Score=150, Expect=1e-36]} {RNA1509_12953, RNA1509_16323, RNA1509_56954} {RNA1310_4375.1, RNA1509_12953, RNA1509_16323, RNA1509_56954} {RNA1509_12953, RNA1509_16323, RNA1509_56954, RNA815_1280}
21. MligTC455_50253 44 0.92 Mlig455_031495

Neo: -

Age: -

GABRB2 0.951 - - - - 0.951 - Mlig455_031495 {REF} {Length: 2129} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=58.3]} {Human: ENSG00000145864, GABRB2, gamma-aminobutyric acid type A receptor beta2 subunit, [Score=71.2, Expect=6e-14]} {Mouse: ENSMUSG00000007653, Gabrb2, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2, [Score=67.8, Expect=1e-12]; ENSMUSG00000029212, Gabrb1, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1, [Score=67.4, Expect=1e-12]} {Dmel: FBgn0024963, GluClalpha, [Score=54.3, Expect=3e-08]} {Celegans: WBGene00001594, glc-4, Glutamate-gated ChLoride channel, [Score=66.6, Expect=2e-12]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=70.1, Expect=9e-14]} {RNA1310_46931} {RNA815_25428}
22. MligTC455_47575 203 4.23 Mlig455_068827

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.457

MAN1C1 0.95 - - - - 0.950 - Mlig455_068827 {REF} {Length: 3468} {Pfam: Glycosyl hydrolase family 47 [PF01532.22, score=378.5]} {Human: ENSG00000117643, MAN1C1, mannosidase alpha class 1C member 1, [Score=268, Expect=7e-82]; ENSG00000198162, MAN1A2, mannosidase alpha class 1A member 2, [Score=268, Expect=2e-81]} {Mouse: ENSMUSG00000037306, Man1c1, mannosidase, alpha, class 1C, member 1, [Score=267, Expect=2e-81]; ENSMUSG00000008763, Man1a2, mannosidase, alpha, class 1A, member 2, [Score=267, Expect=2e-81]; ENSMUSG00000003746, Man1a, mannosidase 1, alpha, [Score=264, Expect=6e-80]} {Dmel: FBgn0259170, alpha-Man-Ia, alpha-Mannosidase class I a, [Score=268, Expect=1e-81]} {Celegans: WBGene00008258, mans-2, Mannosyl-oligosaccharide 1,2-alpha-mannosidase C52E4.5, [Score=250, Expect=1e-75]} {Smed: dd_Smed_v6_6801_0_1, dd_Smed_v6_6801_0_1, [Score=267, Expect=3e-82]} {RNA1509_48511, RNA1509_9530} {RNA1310_9474.1, RNA1509_48511, RNA1509_9530} {RNA1509_48511, RNA1509_9530, RNA815_6962}

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