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Results for MligTC455_32420

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_32420 549 11.44 Mlig455_039348

Neo: -

Age: logFC(26M/2M)=-0.499

 NWD2 Mlig455_039348 {REF} {Length: 8236} {TRANSSPLICED} {Pfam: NACHT domain [PF05729.14, score=43.5]; AAA ATPase domain [PF13191.8, score=38.9]; Dpy-30 motif [PF05186.15, score=31.9]; AAA domain [PF13401.8, score=20.4]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=445, Expect=1e-127]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=438, Expect=1e-125]} {Dmel: FBgn0038397, CG10185, [Score=536, Expect=2e-159]} {Celegans: WBGene00020254, T05C3.2, [Score=549, Expect=1e-163]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=295, Expect=2e-80]} {RNA1509_3054, RNA1509_32303, RNA1509_34526, RNA1509_42986} {RNA1310_425, RNA1509_3054, RNA1509_32303, RNA1509_34526, RNA1509_42986} {RNA1509_3054, RNA1509_32303, RNA1509_34526, RNA1509_42986, RNA815_139.1}

Cumulative graph for MligTC455_32420

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.153 3.836 0.29912 0.94873
RegionR2 0.273 3.836 0.60804 0.95638
RegionR3 -0.288 3.836 0.50670 0.99712
RegionR4 0.692 3.836 0.19426 0.47186
RegionR5 -0.199 3.836 0.61947 0.97508
RegionR6 -0.534 3.836 0.24264 0.82764
RegionR7 -0.54 3.836 0.35307 0.98931
RegionR8 -0.556 3.836 0.44186 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.606 3.836 0.04690 0.68554
RegenerationR2 0.536 3.836 0.20337 0.65014
RegenerationR3 -0.259 3.836 0.60349 0.90936
RegenerationR4 -0.738 3.836 0.15690 0.58831
RegenerationR5 0.018 3.836 0.97168 1.00000
RegenerationR6 0.384 3.836 0.45818 0.77622
RegenerationBL 0.799 3.836 0.16394 0.48551
RegenerationTP -1.364 3.836 0.08878 0.46942


Genes with expression patterns similar to MligTC455_32420

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_32420 549 11.44 Mlig455_039348

Neo: -

Age: logFC(26M/2M)=-0.499

 NWD2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_039348 {REF} {Length: 8236} {TRANSSPLICED} {Pfam: NACHT domain [PF05729.14, score=43.5]; AAA ATPase domain [PF13191.8, score=38.9]; Dpy-30 motif [PF05186.15, score=31.9]; AAA domain [PF13401.8, score=20.4]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=445, Expect=1e-127]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=438, Expect=1e-125]} {Dmel: FBgn0038397, CG10185, [Score=536, Expect=2e-159]} {Celegans: WBGene00020254, T05C3.2, [Score=549, Expect=1e-163]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=295, Expect=2e-80]} {RNA1509_3054, RNA1509_32303, RNA1509_34526, RNA1509_42986} {RNA1310_425, RNA1509_3054, RNA1509_32303, RNA1509_34526, RNA1509_42986} {RNA1509_3054, RNA1509_32303, RNA1509_34526, RNA1509_42986, RNA815_139.1}
2. MligTC455_32419 319 6.65 Mlig455_013944

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.686

 NWD2 5.1 0.769 0.786 0.767 0.910 0.882 0.986 Mlig455_013944 {REF} {Length: 3190} {TRANSSPLICED} {Pfam: Dpy-30 motif [PF05186.15, score=33.8]; AAA ATPase domain [PF13191.8, score=29.3]; NACHT domain [PF05729.14, score=19.8]; ATPase domain predominantly from Archaea [PF01637.20, score=19.1]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=130, Expect=2e-30]; ENSG00000188039, NWD1, NACHT and WD repeat domain containing 1, [Score=128, Expect=9e-30]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=127, Expect=2e-29]; ENSMUSG00000048148, Nwd1, NACHT and WD repeat domain containing 1, [Score=121, Expect=9e-28]} {Dmel: FBgn0038397, CG10185, [Score=193, Expect=6e-51]} {Celegans: WBGene00020254, T05C3.2, [Score=196, Expect=9e-52]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=83.2, Expect=3e-16]} {RNA1509_34526} {RNA1310_322} {RNA815_139.1}
3. MligTC455_23540 1720 35.83 Mlig455_001160, Mlig455_070570

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.344

Regeneration-downregulated TP: -1.716

Regeneration-depleted TP: -1.716

 3.153 - - 0.708 0.738 0.754 0.953

Mlig455_001160 {REF} {Length: 1879} {TRANSSPLICED} {Pfam: Lectin C-type domain [PF00059.23, score=19.5]} {RNA1509_24566} {RNA1310_15626.1} {RNA815_17776}

Mlig455_070570 {REF} {Length: 2014} {TRANSSPLICED} {Pfam: Lectin C-type domain [PF00059.23, score=20.9]} {RNA1509_38964} {RNA1310_15626.1, RNA1509_38964} {RNA1509_38964, RNA815_8594}
4. MligTC455_47463 1002 20.88 Mlig455_029130

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.618

 CSMD3 2.673 - - - 0.912 0.799 0.962 Mlig455_029130 {REF} {Length: 3874} {Pfam: CUB domain [PF00431.22, score=96.2]; Wnt and FGF inhibitory regulator [PF13908.8, score=19.1]} {Human: ENSG00000164796, CSMD3, CUB and Sushi multiple domains 3, [Score=97.1, Expect=4e-20]; ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=94.0, Expect=4e-19]; ENSG00000121904, CSMD2, CUB and Sushi multiple domains 2, [Score=94.0, Expect=4e-19]} {Mouse: ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=95.9, Expect=8e-20]; ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=95.9, Expect=7e-20]; ENSMUSG00000028804, Csmd2, CUB and Sushi multiple domains 2, [Score=95.9, Expect=9e-20]} {Dmel: FBgn0003719, tld, tolloid, [Score=59.3, Expect=8e-09]} {Celegans: WBGene00008294, clec-11, C-type LECtin, [Score=55.5, Expect=6e-08]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=72.8, Expect=3e-13]} {RNA1509_13757, RNA1509_36172, RNA1509_47793, RNA1509_50887, RNA1509_58560, RNA1509_6830} {RNA1310_5183.1, RNA1509_13757, RNA1509_36172, RNA1509_47793, RNA1509_50887, RNA1509_58560, RNA1509_6830} {RNA1509_13757, RNA1509_36172, RNA1509_47793, RNA1509_50887, RNA1509_58560, RNA1509_6830, RNA815_5152}
5. MligTC455_50914 714 14.87 Mlig455_005873

Neo: -

Age: -

Region-enriched R2: 2.125/0.01399

 DNHD1 2.587 - - 0.818 0.815 - 0.954 Mlig455_005873 {REF} {Length: 14506} {Pfam: Dynein heavy chain, N-terminal region 2 [PF08393.15, score=207.8]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=114.3]; P-loop containing dynein motor region D4 [PF12780.9, score=60.3]; Microtubule-binding stalk of dynein motor [PF12777.9, score=54.5]; P-loop containing dynein motor region [PF12775.9, score=46.5]; Dynein heavy chain C-terminal domain [PF18199.3, score=42.8]; Dynein heavy chain AAA lid domain [PF17852.3, score=38.9]; AAA domain [PF13401.8, score=22.7]; Dynein heavy chain AAA lid domain [PF18198.3, score=22.0]; Protein of unknown function (DUF815) [PF05673.15, score=20.3]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=19.7]} {Human: ENSG00000179532, DNHD1, dynein heavy chain domain 1, [Score=159, Expect=1e-37]} {Mouse: ENSMUSG00000030882, Dnhd1, dynein heavy chain domain 1, [Score=177, Expect=3e-43]} {Dmel: FBgn0013811, Dhc62B, Dynein heavy chain at 62B, [Score=114, Expect=4e-24]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=82.0, Expect=1e-14]} {Smed: dd_Smed_v6_8984_0_1, dd_Smed_v6_8984_0_1, [Score=331, Expect=5e-90]} {RNA1509_32900} {RNA1310_31} {RNA815_1203}
6. MligTC455_49448 237 4.94 Mlig455_057665

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.549

 PRKCQ 2.539 - - 0.763 0.809 - 0.967 Mlig455_057665 {REF} {Length: 2763} {Pfam: Protein kinase domain [PF00069.27, score=119.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=84.8]; Kinase-like [PF14531.8, score=23.9]} {Human: ENSG00000065675, PRKCQ, protein kinase C theta, [Score=90.1, Expect=1e-18]; ENSG00000067606, PRKCZ, protein kinase C zeta, [Score=89.4, Expect=2e-18]; ENSG00000281877, RPS6KA1, ribosomal protein S6 kinase A1, [Score=88.6, Expect=4e-18]; ENSG00000117676, RPS6KA1, ribosomal protein S6 kinase A1, [Score=88.6, Expect=4e-18]; ENSG00000163558, PRKCI, protein kinase C iota, [Score=88.2, Expect=5e-18]; ENSG00000108443, RPS6KB1, ribosomal protein S6 kinase B1, [Score=87.8, Expect=5e-18]; ENSG00000027075, PRKCH, protein kinase C eta, [Score=85.9, Expect=2e-17]; ENSG00000171132, PRKCE, protein kinase C epsilon, [Score=85.9, Expect=4e-17]} {Mouse: ENSMUSG00000029053, Prkcz, protein kinase C, zeta, [Score=88.6, Expect=3e-18]; ENSMUSG00000003644, Rps6ka1, ribosomal protein S6 kinase polypeptide 1, [Score=88.2, Expect=4e-18]; ENSMUSG00000021108, Prkch, protein kinase C, eta, [Score=87.8, Expect=5e-18]; ENSMUSG00000037643, Prkci, protein kinase C, iota, [Score=87.8, Expect=4e-18]; ENSMUSG00000020516, Rps6kb1, ribosomal protein S6 kinase, polypeptide 1, [Score=87.8, Expect=4e-18]; ENSMUSG00000031309, Rps6ka3, ribosomal protein S6 kinase polypeptide 3, [Score=87.4, Expect=7e-18]; ENSMUSG00000116203, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=84.7, Expect=6e-17]; ENSMUSG00000045038, Prkce, protein kinase C, epsilon, [Score=84.7, Expect=6e-17]; ENSMUSG00000025665, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=84.7, Expect=6e-17]; ENSMUSG00000026778, Prkcq, protein kinase C, theta, [Score=84.3, Expect=7e-17]; ENSMUSG00000019699, Akt3, thymoma viral proto-oncogene 3, [Score=84.3, Expect=4e-17]} {Dmel: FBgn0003093, Pkc98E, Protein C kinase 98E, [Score=86.7, Expect=7e-18]} {Celegans: WBGene00004032, pkc-1, Protein kinase C-like 1B, [Score=84.7, Expect=3e-17]} {Smed: dd_Smed_v6_8010_0_1, dd_Smed_v6_8010_0_1, [Score=88.2, Expect=2e-18]} {RNA1509_57646} {RNA1310_18713, RNA1509_57646} {RNA1509_57646, RNA815_7871}
7. MligTC455_50685 443 9.22 Mlig455_008930

Neo: -

Age: Up-Down-Down

 LRRK2 2.531 - - - 0.800 0.743 0.988 Mlig455_008930 {REF} {Length: 12042} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=151.5]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=75.1]; TIR domain [PF13676.8, score=67.0]; Ras family [PF00071.24, score=44.4]; Leucine rich repeat [PF13855.8, score=39.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=24.7]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=158, Expect=1e-37]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=161, Expect=9e-39]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=146, Expect=3e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=122, Expect=5e-27]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=714, Expect=0.0]} {RNA1509_2407, RNA1509_24338, RNA1509_49350} {RNA1310_77.1, RNA1509_2407, RNA1509_24338, RNA1509_49350} {RNA1509_2407, RNA1509_24338, RNA1509_49350, RNA815_489}
8. MligTC455_47462 529 11.01 Mlig455_012033

Neo: -

Age: Down-Up-Down

 CSMD3 2.512 - 0.706 - 0.839 - 0.967 Mlig455_012033 {REF} {Length: 3072} {Pfam: CUB domain [PF00431.22, score=95.8]; Wnt and FGF inhibitory regulator [PF13908.8, score=19.1]} {Human: ENSG00000164796, CSMD3, CUB and Sushi multiple domains 3, [Score=97.1, Expect=5e-20]; ENSG00000183117, CSMD1, CUB and Sushi multiple domains 1, [Score=93.2, Expect=9e-19]} {Mouse: ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=95.9, Expect=8e-20]; ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=94.7, Expect=2e-19]; ENSMUSG00000028804, Csmd2, CUB and Sushi multiple domains 2, [Score=92.4, Expect=9e-19]} {Dmel: FBgn0003719, tld, tolloid, [Score=58.5, Expect=2e-08]} {Celegans: WBGene00008294, clec-11, C-type LECtin, [Score=52.8, Expect=5e-07]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=77.0, Expect=2e-14]} {RNA1509_35718, RNA1509_6830} {RNA1310_5183.1, RNA1509_35718} {RNA1509_35718, RNA815_5152}
9. MligTC455_44042 460 9.59 Mlig455_021815

Neo: -

Age: logFC(26M/2M)=-0.341

 CCDC181 2.425 - - 0.714 0.759 - 0.952 Mlig455_021815 {REF} {Length: 2436} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=29.1]} {Human: ENSG00000117477, CCDC181, coiled-coil domain containing 181, [Score=70.5, Expect=2e-12]} {Mouse: ENSMUSG00000026578, Ccdc181, coiled-coil domain containing 181, [Score=72.0, Expect=4e-13]} {Smed: dd_Smed_v6_8117_0_1, dd_Smed_v6_8117_0_1, [Score=76.6, Expect=6e-15]} {RNA1509_20789} {RNA1310_10957.1, RNA1509_20789} {RNA1509_20789, RNA815_9557}
10. MligTC455_40875 441 9.2 Mlig455_013461

Neo: -

Age: Up-Down-Down

 ATP10B 1.882 - - - 0.927 - 0.955 Mlig455_013461 {REF} {Length: 5549} {TRANSSPLICED} {Pfam: Phospholipid-translocating P-type ATPase C-terminal [PF16212.7, score=164.9]; Phospholipid-translocating ATPase N-terminal [PF16209.7, score=81.0]; haloacid dehalogenase-like hydrolase [PF00702.28, score=44.4]; Cation transport ATPase (P-type) [PF13246.8, score=42.9]; E1-E2 ATPase [PF00122.22, score=27.9]} {Human: ENSG00000118322, ATP10B, ATPase phospholipid transporting 10B (putative), [RH, Score=902, Expect=0.0]} {Mouse: ENSMUSG00000055415, Atp10b, ATPase, class V, type 10B, [RH, Score=898, Expect=0.0]} {Dmel: FBgn0030747, CG4301, [Score=498, Expect=9e-153]} {Celegans: WBGene00012360, tat-3, Phospholipid-transporting ATPase, [RH, Score=885, Expect=0.0]} {Smed: dd_Smed_v6_5042_0_1, dd_Smed_v6_5042_0_1, [RH, Score=1040, Expect=0.0]} {RNA1509_11694} {RNA1310_793} {RNA815_3912}
11. MligTC455_10429 789 16.44 Mlig455_070400

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.548

 WDR66 1.79 - - - 0.952 - 0.838 Mlig455_070400 {REF} {Length: 5313} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=80.7]; Cornifin (SPRR) family [PF02389.17, score=34.2]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=24.9]} {Human: ENSG00000158023, WDR66, WD repeat domain 66, [RH, Score=780, Expect=0.0]} {Mouse: ENSMUSG00000029442, Wdr66, WD repeat domain 66, [RH, Score=769, Expect=0.0]} {Dmel: FBgn0039867, CstF50, Cleavage stimulation factor 50 kD subunit, [Score=51.2, Expect=5e-06]} {Celegans: WBGene00006820, unc-89, Muscle M-line assembly protein unc-89, [Score=67.8, Expect=6e-11]} {Smed: dd_Smed_v6_11127_0_2, dd_Smed_v6_11127_0_2, [RH, Score=943, Expect=0.0]} {RNA1509_3046} {RNA1310_3690} {RNA815_918.1}
12. MligTC455_37312 666 13.87 Mlig455_045010, Mlig455_047368

Neo: -

Age: -

 TMTC3 1.733 - - - 0.976 0.757 -

Mlig455_045010 {REF} {Length: 4205} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=103.9]; Tetratricopeptide repeat [PF00515.30, score=103.7]; Tetratricopeptide repeat [PF13181.8, score=92.3]; Tetratricopeptide repeat [PF13431.8, score=81.8]; Domain of unknown function (DUF1736) [PF08409.13, score=69.0]; Tetratricopeptide repeat [PF14559.8, score=65.0]; Tetratricopeptide repeat [PF13424.8, score=64.8]; Tetratricopeptide repeat [PF13428.8, score=57.6]; Tetratricopeptide repeat [PF13432.8, score=56.3]; TPR repeat [PF13414.8, score=53.5]; Tetratricopeptide repeat [PF13176.8, score=37.7]; Tetratricopeptide repeat [PF13371.8, score=27.8]; Tetratricopeptide repeat [PF13174.8, score=25.2]; Tetratricopeptide repeat [PF13374.8, score=20.0]; Est1 DNA/RNA binding domain [PF10373.11, score=18.8]} {Human: ENSG00000139324, TMTC3, transmembrane and tetratricopeptide repeat containing 3, [RH, Score=745, Expect=0.0]} {Mouse: ENSMUSG00000036676, Tmtc3, transmembrane and tetratricopeptide repeat containing 3, [RH, Score=736, Expect=0.0]} {Dmel: FBgn0020312, CG4050, [RH, Score=635, Expect=0.0]} {Celegans: WBGene00018175, F38B6.6, Transmembrane and TPR repeat-containing protein F38B6.6, [RH, Score=230, Expect=3e-64]} {Smed: dd_Smed_v6_6940_0_1, dd_Smed_v6_6940_0_1, [RH, Score=707, Expect=0.0]} {RNA1509_14231} {RNA1310_2545} {RNA815_4400}

Mlig455_047368 {REF} {Length: 4043} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=104.2]; Tetratricopeptide repeat [PF00515.30, score=104.0]; Tetratricopeptide repeat [PF13181.8, score=92.7]; Tetratricopeptide repeat [PF13431.8, score=82.0]; Domain of unknown function (DUF1736) [PF08409.13, score=69.0]; Tetratricopeptide repeat [PF14559.8, score=65.8]; Tetratricopeptide repeat [PF13424.8, score=65.0]; Tetratricopeptide repeat [PF13428.8, score=57.5]; TPR repeat [PF13414.8, score=53.8]; Tetratricopeptide repeat [PF13432.8, score=53.3]; Tetratricopeptide repeat [PF13176.8, score=37.9]; Tetratricopeptide repeat [PF13371.8, score=28.1]; Tetratricopeptide repeat [PF13174.8, score=25.5]; Tetratricopeptide repeat [PF13374.8, score=20.3]; Est1 DNA/RNA binding domain [PF10373.11, score=18.7]} {Human: ENSG00000139324, TMTC3, transmembrane and tetratricopeptide repeat containing 3, [RH, Score=747, Expect=0.0]} {Mouse: ENSMUSG00000036676, Tmtc3, transmembrane and tetratricopeptide repeat containing 3, [RH, Score=738, Expect=0.0]} {Dmel: FBgn0020312, CG4050, [RH, Score=635, Expect=0.0]} {Celegans: WBGene00018175, F38B6.6, Transmembrane and TPR repeat-containing protein F38B6.6, [RH, Score=231, Expect=1e-64]} {Smed: dd_Smed_v6_6940_0_1, dd_Smed_v6_6940_0_1, [RH, Score=711, Expect=0.0]} {RNA1509_14231} {RNA1310_2545} {RNA815_4400}
13. MligTC455_53167 621 12.93 Mlig455_035205, Mlig455_035254

Neo: -

Age: -

 TEP1 1.726 - - - 0.774 - 0.952

Mlig455_035205 {REF} {Length: 3182} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=42.8]; NACHT domain [PF05729.14, score=19.7]} {Human: ENSG00000129566, TEP1, telomerase associated protein 1, [Score=143, Expect=4e-34]} {Mouse: ENSMUSG00000006281, Tep1, telomerase associated protein 1, [Score=121, Expect=2e-27]} {Smed: dd_Smed_v6_9074_0_1, dd_Smed_v6_9074_0_1, [RH, Score=335, Expect=8e-102]} {RNA1509_45368, RNA1509_7043} {RNA1310_6418, RNA1509_45368} {RNA1509_45368, RNA815_7934}

Mlig455_035254 {REF} {Length: 3176} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=42.8]; NACHT domain [PF05729.14, score=19.7]; AAA ATPase domain [PF13191.8, score=19.7]} {Human: ENSG00000129566, TEP1, telomerase associated protein 1, [Score=142, Expect=6e-34]} {Mouse: ENSMUSG00000006281, Tep1, telomerase associated protein 1, [Score=119, Expect=1e-26]} {Smed: dd_Smed_v6_9074_0_1, dd_Smed_v6_9074_0_1, [RH, Score=329, Expect=2e-99]} {RNA1509_7043} {RNA1310_6418, RNA1509_7043} {RNA1509_7043, RNA815_7934}
14. MligTC455_46564 403 8.4 Mlig455_040238

Neo: -

Age: -

 1.711 - - - 0.729 - 0.982 Mlig455_040238 {REF} {Length: 3013} {RNA1509_9486} {RNA1310_9854} {RNA815_15545}
15. MligTC455_29164 899 18.73 Mlig455_006856

Neo: -

Age: Down-Up-Up

 ANKRD42 1.705 - - - - 0.745 0.960 Mlig455_006856 {REF} {Length: 2038} {TRANSSPLICED} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=124.3]; Ankyrin repeats (3 copies) [PF12796.9, score=118.0]; Ankyrin repeats (many copies) [PF13857.8, score=106.6]; Ankyrin repeat [PF13606.8, score=85.3]; Ankyrin repeat [PF00023.32, score=69.9]} {Human: ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [RH, Score=493, Expect=2e-170]} {Mouse: ENSMUSG00000041343, Ankrd42, ankyrin repeat domain 42, [RH, Score=491, Expect=1e-169]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=143, Expect=1e-35]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=125, Expect=4e-30]} {Smed: dd_Smed_v6_10615_0_1, dd_Smed_v6_10615_0_1, [RH, Score=621, Expect=0.0]} {RNA1509_29991} {RNA1310_12980.1} {RNA815_2353.1}
16. MligTC455_38448 390 8.12 Mlig455_064678

Neo: -

Age: Down-Down-Up

 1.663 - - - - 0.712 0.951 Mlig455_064678 {REF} {Length: 2178} {TRANSSPLICED} {Pfam: PH domain [PF00169.31, score=33.8]} {Dmel: FBgn0263353, CG11000, [RH, Score=68.6, Expect=1e-12]} {Celegans: WBGene00009534, F38B7.3, [RH, Score=82.4, Expect=5e-17]} {Smed: dd_Smed_v6_4018_0_1, dd_Smed_v6_4018_0_1, [RH, Score=118, Expect=8e-30]} {RNA1509_10365} {RNA1310_20310, RNA1509_10365} {RNA1509_10365, RNA815_26365}
17. MligTC455_41077 483 10.07 Mlig455_031143, Mlig455_031151

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.359

 SLC8A3 0.969 - - - - - 0.969

Mlig455_031143 {REF} {Length: 4359} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=180.5]; Calx-beta domain [PF03160.16, score=179.5]; C-terminal extension of sodium/calcium exchanger domain [PF16494.7, score=92.3]} {Human: ENSG00000100678, SLC8A3, solute carrier family 8 member A3, [RH, Score=952, Expect=0.0]; ENSG00000183023, SLC8A1, solute carrier family 8 member A1, [RH, Score=932, Expect=0.0]} {Mouse: ENSMUSG00000079055, Slc8a3, solute carrier family 8 (sodium/calcium exchanger), member 3, [RH, Score=945, Expect=0.0]; ENSMUSG00000054640, Slc8a1, solute carrier family 8 (sodium/calcium exchanger), member 1, [RH, Score=936, Expect=0.0]; ENSMUSG00000030376, Slc8a2, solute carrier family 8 (sodium/calcium exchanger), member 2, [RH, Score=917, Expect=0.0]} {Dmel: FBgn0013995, Calx, Na/Ca-exchange protein, [RH, Score=829, Expect=0.0]} {Celegans: WBGene00003567, ncx-2, Na/Ca eXchangers, [RH, Score=878, Expect=0.0]} {Smed: dd_Smed_v6_3303_0_1, dd_Smed_v6_3303_0_1, [RH, Score=997, Expect=0.0]} {RNA1509_12866} {RNA1310_2685.1} {RNA815_13452}

Mlig455_031151 {REF} {Length: 5266} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=179.9]; Calx-beta domain [PF03160.16, score=164.6]; C-terminal extension of sodium/calcium exchanger domain [PF16494.7, score=91.7]} {Human: ENSG00000100678, SLC8A3, solute carrier family 8 member A3, [Score=523, Expect=1e-169]; ENSG00000183023, SLC8A1, solute carrier family 8 member A1, [Score=498, Expect=7e-160]} {Mouse: ENSMUSG00000079055, Slc8a3, solute carrier family 8 (sodium/calcium exchanger), member 3, [Score=520, Expect=3e-168]; ENSMUSG00000054640, Slc8a1, solute carrier family 8 (sodium/calcium exchanger), member 1, [Score=503, Expect=7e-162]} {Dmel: FBgn0013995, Calx, Na/Ca-exchange protein, [Score=490, Expect=2e-160]} {Celegans: WBGene00003567, ncx-2, Na/Ca eXchangers, [Score=492, Expect=5e-158]} {Smed: dd_Smed_v6_3303_0_1, dd_Smed_v6_3303_0_1, [Score=549, Expect=4e-180]} {RNA1509_12866} {RNA1310_2685.2} {RNA815_13452}
18. MligTC455_43120 247 5.15 Mlig455_025263

Neo: -

Age: Up-Down-Down

 0.969 - - - - - 0.969 Mlig455_025263 {REF} {Length: 4290} {RNA1509_20151} {RNA1310_8688.1} {RNA815_9458.1}
19. MligTC455_18604 180 3.74 Mlig455_000584

Neo: -

Age: logFC(26M/2M)=-0.781

 0.968 - - - - - 0.968 Mlig455_000584 {REF} {Length: 1262} {Pfam: Family of unknown function (DUF5582) [PF17819.3, score=54.4]} {Mouse: ENSMUSG00000022798, 4930435E12Rik, RIKEN cDNA 4930435E12 gene, [RH, Score=59.3, Expect=4e-11]} {RNA1509_10400} {RNA1310_50669.1} {RNA815_25237}
20. MligTC455_42484 246 5.12 Mlig455_046416

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.313

Region-enriched R2: 2.983/0.00930

 0.967 - - - - - 0.967 Mlig455_046416 {REF} {Length: 1006} {RNA1310_40237.1} {RNA815_18246}
21. MligTC455_28445 61 1.26 Mlig455_041591

Neo: -

Age: -

 0.96 - - - - - 0.960 Mlig455_041591 {REF} {Length: 390} {NoTransDecoderORF} {RNA1509_26115} {RNA1310_50055} {RNA815_26110}
22. MligTC455_48208 763 15.9 Mlig455_004667, Mlig455_004732

Neo: -

Age: logFC(26M/2M)=-0.337

Region-enriched R2: 2.161/0.00459

 0.96 - - - - - 0.960

Mlig455_004667 {REF} {Length: 3462} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=55.5]; Ankyrin repeats (many copies) [PF13637.8, score=47.4]; Ankyrin repeats (many copies) [PF13857.8, score=32.1]; Ankyrin repeat [PF13606.8, score=29.8]; Ankyrin repeat [PF00023.32, score=29.3]} {Dmel: FBgn0259179, CG42284, [RH, Score=74.7, Expect=9e-14]} {Celegans: WBGene00009375, F34D10.6, [Score=71.2, Expect=2e-12]} {Smed: dd_Smed_v6_5594_0_7, dd_Smed_v6_5594_0_7, [Score=742, Expect=0.0]} {RNA1509_29755} {RNA1310_4332} {RNA815_1422}

Mlig455_004732 {REF} {Length: 3983} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=67.7]; Ankyrin repeats (many copies) [PF13637.8, score=59.4]; Ankyrin repeat [PF13606.8, score=43.2]; Ankyrin repeat [PF00023.32, score=41.1]; Ankyrin repeats (many copies) [PF13857.8, score=39.6]} {Dmel: FBgn0259179, CG42284, [RH, Score=74.7, Expect=8e-14]} {Celegans: WBGene00009375, F34D10.6, [Score=71.6, Expect=2e-12]} {Smed: dd_Smed_v6_5594_0_4, dd_Smed_v6_5594_0_4, [RH, Score=823, Expect=0.0]} {RNA1509_3545} {RNA1310_4332, RNA1509_3545} {RNA1509_3545, RNA815_1422}
23. MligTC455_31289 316 6.57 Mlig455_013898

Neo: -

Age: logFC(26M/2M)=-0.339

Region-enriched R2: 2.715/0.03239

 DECR2 0.957 - - - - - 0.957 Mlig455_013898 {REF} {Length: 5238} {Pfam: short chain dehydrogenase [PF00106.27, score=99.4]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=67.1]; KR domain [PF08659.12, score=28.0]} {Human: ENSG00000242612, DECR2, 2,4-dienoyl-CoA reductase 2, [Score=139, Expect=3e-37]; ENSG00000274296, DECR2, 2,4-dienoyl-CoA reductase 2, [Score=139, Expect=3e-37]} {Mouse: ENSMUSG00000036775, Decr2, 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal, [Score=138, Expect=4e-37]} {Dmel: FBgn0021765, scu, scully, [Score=55.1, Expect=3e-08]} {Celegans: WBGene00011467, decr-1.3, Probable 2,4-dienoyl-CoA reductase 3, [Score=67.4, Expect=4e-12]} {Smed: dd_Smed_v6_6646_0_2, dd_Smed_v6_6646_0_2, [Score=55.1, Expect=2e-08]} {RNA1509_52416} {RNA1310_1377.1} {RNA815_9152.1}
24. MligTC455_41358 245 5.1 Mlig455_029627

Neo: -

Age: -

 PPP1R42 0.955 - - - - - 0.955 Mlig455_029627 {REF} {Length: 2517} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=62.4]; Leucine rich repeat [PF13855.8, score=47.1]; Leucine-rich repeat [PF14580.8, score=35.6]} {Human: ENSG00000178125, PPP1R42, protein phosphatase 1 regulatory subunit 42, [RH, Score=211, Expect=7e-66]} {Mouse: ENSMUSG00000025916, Ppp1r42, protein phosphatase 1, regulatory subunit 42, [RH, Score=196, Expect=1e-59]} {Dmel: FBgn0046697, Ppr-Y, [Score=53.5, Expect=1e-07]} {Celegans: WBGene00189952, K10D2.8, [Score=56.6, Expect=7e-09]} {Smed: dd_Smed_v6_7268_1_2, dd_Smed_v6_7268_1_2, [RH, Score=228, Expect=3e-73]} {RNA1509_39009, RNA1509_39771} {RNA1310_21948.1, RNA1509_39009, RNA1509_39771} {RNA1509_39009, RNA1509_39771, RNA815_20117}
25. MligTC455_47217 532 11.09 Mlig455_006553

Neo: -

Age: -

 LRRC34 0.955 - - - - - 0.955 Mlig455_006553 {REF} {Length: 2596} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=104.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=23.5]; Leucine Rich Repeat [PF00560.35, score=22.3]; Leucine rich repeat [PF13855.8, score=20.8]} {Human: ENSG00000171757, LRRC34, leucine rich repeat containing 34, [RH, Score=283, Expect=2e-91]} {Mouse: ENSMUSG00000027702, Lrrc34, leucine rich repeat containing 34, [RH, Score=336, Expect=3e-112]} {Dmel: FBgn0033369, CG8197, [RH, Score=58.2, Expect=5e-09]} {Celegans: WBGene00009201, F28C1.3, Protein phosphatase 1 regulatory subunit 37 homolog, [Score=53.1, Expect=3e-07]} {Smed: dd_Smed_v6_9926_1_1, dd_Smed_v6_9926_1_1, [RH, Score=382, Expect=1e-130]} {RNA1509_9806} {RNA1310_21676.1, RNA1509_9806} {RNA1509_9806, RNA815_6669}
26. MligTC455_42757 88 1.83 Mlig455_009132

Neo: -

Age: -

 LRFN1 0.954 - - - - - 0.954 Mlig455_009132 {REF} {Length: 4463} {Pfam: Leucine rich repeat [PF13855.8, score=55.0]; Immunoglobulin domain [PF13927.8, score=43.4]; Immunoglobulin V-set domain [PF07686.19, score=39.9]; Immunoglobulin domain [PF00047.27, score=39.5]; Immunoglobulin I-set domain [PF07679.18, score=35.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=30.0]; Immunoglobulin domain [PF13895.8, score=28.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=20.0]} {Human: ENSG00000128011, LRFN1, leucine rich repeat and fibronectin type III domain containing 1, [RH, Score=111, Expect=1e-24]} {Mouse: ENSMUSG00000030600, Lrfn1, leucine rich repeat and fibronectin type III domain containing 1, [RH, Score=112, Expect=4e-25]} {Dmel: FBgn0032484, kek4, kekkon4, [Score=71.2, Expect=2e-12]} {Celegans: WBGene00010621, egg-6, Leucine-rich repeat-containing protein egg-6, [Score=71.2, Expect=2e-12]} {Smed: dd_Smed_v6_18031_0_1, dd_Smed_v6_18031_0_1, [Score=124, Expect=3e-29]} {RNA1310_5378.1} {RNA815_13491}
27. MligTC455_33008 512 10.66 Mlig455_032378, Mlig455_032404

Neo: -

Age: -

 0.953 - - - - - 0.953

Mlig455_032378 {REF} {Length: 955} {RNA1509_40043} {RNA1310_38774} {RNA815_34620}

Mlig455_032404 {REF} {Length: 2216} {RNA1509_40043} {RNA1310_38774, RNA1509_40043} {RNA1509_40043, RNA815_34620}
28. MligTC455_44626 238 4.96 Mlig455_030645

Neo: -

Age: Up-Down-Down

 CFAP47 0.953 - - - 0.953 - - Mlig455_030645 {REF} {Length: 3012} {Pfam: Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin [PF15780.7, score=122.7]; Transmembrane protein 131-like N-terminal [PF12371.10, score=49.5]; Protein of unknown function (DUF1573) [PF07610.13, score=34.5]; MSP (Major sperm protein) domain [PF00635.28, score=34.0]; Flagellar-associated PapD-like [PF14874.8, score=20.6]; Calponin homology (CH) domain [PF00307.33, score=18.8]} {Human: ENSG00000165164, CFAP47, cilia and flagella associated protein 47, [RH, Score=1603, Expect=0.0]} {Mouse: ENSMUSG00000073077, Gm7173, predicted gene 7173, [RH, Score=1587, Expect=0.0]} {Smed: dd_Smed_v6_8294_0_2, dd_Smed_v6_8294_0_2, [RH, Score=1746, Expect=0.0]} {RNA1509_1109, RNA1509_38114} {RNA1310_98.1, RNA1509_38114} {RNA1509_38114, RNA815_42.1}
29. MligTC455_33479 272 5.67 Mlig455_071046

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.353

 NWD2 0.952 - - - - - 0.952 Mlig455_071046 {REF} {Length: 6955} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=49.9]; Dpy-30 motif [PF05186.15, score=43.2]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=188, Expect=3e-47]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=184, Expect=4e-46]} {Dmel: FBgn0038397, CG10185, [Score=282, Expect=2e-76]} {Celegans: WBGene00020254, T05C3.2, [Score=270, Expect=2e-72]} {Smed: dd_Smed_v6_74366_0_1, dd_Smed_v6_74366_0_1, [Score=130, Expect=1e-33]} {RNA1509_54932, RNA1509_8321} {RNA1310_329, RNA1509_54932} {RNA1509_54932, RNA815_359}
30. MligTC455_25566 133 2.77 Mlig455_013513

Neo: -

Age: logFC(26M/2M)=-0.283

 ANKAR 0.951 - - - - - 0.951 Mlig455_013513 {REF} {Length: 4806} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=53.6]; Ankyrin repeats (many copies) [PF13857.8, score=25.9]; Ankyrin repeats (3 copies) [PF12796.9, score=22.4]; Ankyrin repeats (many copies) [PF13637.8, score=19.3]} {Human: ENSG00000151687, ANKAR, ankyrin and armadillo repeat containing, [Score=265, Expect=1e-73]} {Mouse: ENSMUSG00000039342, Ankar, ankyrin and armadillo repeat containing, [Score=292, Expect=3e-83]} {Smed: dd_Smed_v6_10062_0_1, dd_Smed_v6_10062_0_1, [RH, Score=450, Expect=1e-144]} {RNA1509_10980} {RNA1310_5551, RNA1509_10980} {RNA1509_10980, RNA815_1615}
31. MligTC455_37111 1709 35.61 Mlig455_015739, Mlig455_049445, Mlig455_049459

Neo: -

Age: logFC(26M/2M)=-0.249

Region-enriched R2: 1.162/0.04679

 0.95 - - - - - 0.950

Mlig455_015739 {REF} {Length: 1115} {RNA1509_33493} {RNA1310_28591.1} {RNA815_13812.1}

Mlig455_049445 {REF} {Length: 1524} {RNA1509_21694, RNA1509_33493} {RNA1310_28591.1, RNA1509_21694, RNA1509_33493} {RNA1509_21694, RNA1509_33493, RNA815_13812.1}

Mlig455_049459 {REF} {Length: 2200} {RNA1509_21694} {RNA1310_28591.1} {RNA815_13812.1}
32. MligTC455_53822 512 10.67 Mlig455_049342, Mlig455_049421

Neo: -

Age: -

 SMAD6 0.95 - - - 0.950 - -

Mlig455_049342 {REF} {Length: 3658} {TRANSSPLICED} {Pfam: MH2 domain [PF03166.16, score=100.3]; MH1 domain [PF03165.18, score=40.4]} {Human: ENSG00000137834, SMAD6, SMAD family member 6, [Score=92.4, Expect=3e-19]} {Mouse: ENSMUSG00000036867, Smad6, SMAD family member 6, [Score=95.1, Expect=3e-20]} {Dmel: FBgn0020493, Dad, Daughters against dpp, [Score=92.8, Expect=1e-19]} {Celegans: WBGene00004857, sma-3, Dwarfin sma-3, [Score=58.5, Expect=5e-09]} {Smed: dd_Smed_v6_6877_0_1, dd_Smed_v6_6877_0_1, [Score=81.6, Expect=2e-16]} {RNA1509_16358, RNA1509_59885} {RNA1310_7914.1, RNA1509_16358, RNA1509_59885} {RNA1509_16358, RNA1509_59885, RNA815_1361.1}

Mlig455_049421 {REF} {Length: 3513} {TRANSSPLICED} {Pfam: MH2 domain [PF03166.16, score=100.3]; MH1 domain [PF03165.18, score=40.5]} {Human: ENSG00000137834, SMAD6, SMAD family member 6, [Score=92.4, Expect=3e-19]} {Mouse: ENSMUSG00000036867, Smad6, SMAD family member 6, [Score=95.1, Expect=2e-20]} {Dmel: FBgn0020493, Dad, Daughters against dpp, [Score=92.4, Expect=1e-19]} {Celegans: WBGene00004857, sma-3, Dwarfin sma-3, [Score=58.5, Expect=5e-09]} {Smed: dd_Smed_v6_6877_0_1, dd_Smed_v6_6877_0_1, [Score=81.6, Expect=2e-16]} {RNA1509_16358} {RNA1310_7914.1} {RNA815_1361.1}

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