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Results for MligTC455_53167

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_53167 621 12.93 Mlig455_035205, Mlig455_035254

Neo: -

Age: -

TEP1

Mlig455_035205 {REF} {Length: 3182} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=42.8]; NACHT domain [PF05729.14, score=19.7]} {Human: ENSG00000129566, TEP1, telomerase associated protein 1, [Score=143, Expect=4e-34]} {Mouse: ENSMUSG00000006281, Tep1, telomerase associated protein 1, [Score=121, Expect=2e-27]} {Smed: dd_Smed_v6_9074_0_1, dd_Smed_v6_9074_0_1, [RH, Score=335, Expect=8e-102]} {RNA1509_45368, RNA1509_7043} {RNA1310_6418, RNA1509_45368} {RNA1509_45368, RNA815_7934}

Mlig455_035254 {REF} {Length: 3176} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=42.8]; NACHT domain [PF05729.14, score=19.7]; AAA ATPase domain [PF13191.8, score=19.7]} {Human: ENSG00000129566, TEP1, telomerase associated protein 1, [Score=142, Expect=6e-34]} {Mouse: ENSMUSG00000006281, Tep1, telomerase associated protein 1, [Score=119, Expect=1e-26]} {Smed: dd_Smed_v6_9074_0_1, dd_Smed_v6_9074_0_1, [RH, Score=329, Expect=2e-99]} {RNA1509_7043} {RNA1310_6418, RNA1509_7043} {RNA1509_7043, RNA815_7934}

Cumulative graph for MligTC455_53167

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -6.86 3.98 0.04767 0.51920
RegionR2 1.327 3.98 0.10932 0.40842
RegionR3 0.676 3.98 0.43651 0.95368
RegionR4 0.695 3.98 0.45259 0.78130
RegionR5 -0.274 3.98 0.92184 1.00000
RegionR6 1.026 3.98 0.19793 0.76725
RegionR7 1.479 3.98 0.06346 0.48419
RegionR8 1.93 3.98 0.02235 0.29148

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.383 3.98 0.99997 1.00000
RegenerationR2 0.995 3.98 0.03368 0.30284
RegenerationR3 0.696 3.98 0.20121 0.63654
RegenerationR4 0.222 3.98 0.69700 0.95242
RegenerationR5 0.647 3.98 0.24357 0.67683
RegenerationR6 0.125 3.98 0.81823 0.98606
RegenerationBL -0.294 3.98 0.60540 0.95189
RegenerationTP -0.331 3.98 0.57126 0.94515


Genes with expression patterns similar to MligTC455_53167

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_53167 621 12.93 Mlig455_035205, Mlig455_035254

Neo: -

Age: -

TEP1 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_035205 {REF} {Length: 3182} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=42.8]; NACHT domain [PF05729.14, score=19.7]} {Human: ENSG00000129566, TEP1, telomerase associated protein 1, [Score=143, Expect=4e-34]} {Mouse: ENSMUSG00000006281, Tep1, telomerase associated protein 1, [Score=121, Expect=2e-27]} {Smed: dd_Smed_v6_9074_0_1, dd_Smed_v6_9074_0_1, [RH, Score=335, Expect=8e-102]} {RNA1509_45368, RNA1509_7043} {RNA1310_6418, RNA1509_45368} {RNA1509_45368, RNA815_7934}

Mlig455_035254 {REF} {Length: 3176} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=42.8]; NACHT domain [PF05729.14, score=19.7]; AAA ATPase domain [PF13191.8, score=19.7]} {Human: ENSG00000129566, TEP1, telomerase associated protein 1, [Score=142, Expect=6e-34]} {Mouse: ENSMUSG00000006281, Tep1, telomerase associated protein 1, [Score=119, Expect=1e-26]} {Smed: dd_Smed_v6_9074_0_1, dd_Smed_v6_9074_0_1, [RH, Score=329, Expect=2e-99]} {RNA1509_7043} {RNA1310_6418, RNA1509_7043} {RNA1509_7043, RNA815_7934}
2. MligTC455_30366 614 12.78 Mlig455_005372, Mlig455_005424, Mlig455_036242

Neo: -

Age: logFC(26M/2M)=-0.322

C20orf194 2.599 - - - 0.965 0.795 0.839

Mlig455_005372 {REF} {Length: 2621} {Human: ENSG00000088854, C20orf194, chromosome 20 open reading frame 194, [Score=103, Expect=6e-22]} {Mouse: ENSMUSG00000027309, 4930402H24Rik, RIKEN cDNA 4930402H24 gene, [RH, Score=110, Expect=3e-24]} {Smed: dd_Smed_v6_10121_0_1, dd_Smed_v6_10121_0_1, [Score=89.7, Expect=3e-18]} {RNA1509_13613} {RNA1310_6491.1} {RNA815_2468}

Mlig455_005424 {REF} {Length: 829} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_13613} {RNA1310_1263.1} {RNA815_2468}

Mlig455_036242 {REF} {Length: 3746} {Human: ENSG00000088854, C20orf194, chromosome 20 open reading frame 194, [RH, Score=165, Expect=7e-41]} {Mouse: ENSMUSG00000027309, 4930402H24Rik, RIKEN cDNA 4930402H24 gene, [RH, Score=162, Expect=3e-40]} {Smed: dd_Smed_v6_10121_0_1, dd_Smed_v6_10121_0_1, [RH, Score=178, Expect=3e-45]} {RNA1509_13613} {RNA1310_6491.1, RNA1509_13613} {RNA1509_13613, RNA815_2468}
3. MligTC455_40052 513 10.68 Mlig455_035856

Neo: -

Age: -

2.588 - - 0.758 0.871 - 0.959 Mlig455_035856 {REF} {Length: 3180} {TRANSSPLICED} {Smed: dd_Smed_v6_14291_0_1, dd_Smed_v6_14291_0_1, [RH, Score=221, Expect=3e-61]} {RNA1509_6964} {RNA1310_5805} {RNA815_1720}
4. MligTC455_43667 251 5.24 Mlig455_070631

Neo: -

Age: Down-Down-Up

KY 2.57 - - 0.786 0.818 - 0.966 Mlig455_070631 {REF} {Length: 5010} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=114, Expect=3e-25]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=114, Expect=3e-25]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=151, Expect=4e-37]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=139, Expect=2e-34]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=136, Expect=4e-32]} {RNA1509_26818, RNA1509_52206, RNA1509_7582} {RNA1310_2203, RNA1509_26818, RNA1509_52206, RNA1509_7582} {RNA1509_26818, RNA1509_52206, RNA1509_7582, RNA815_6135}
5. MligTC455_46518 283 5.9 Mlig455_004530, Mlig455_028532, Mlig455_064722

Neo: -

Age: -

CHRNA4 2.522 0.712 - - - 0.981 0.829

Mlig455_004530 {REF} {Length: 3050} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=183.3]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=126.0]} {Human: ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=261, Expect=4e-78]} {Mouse: ENSMUSG00000027577, Chrna4, cholinergic receptor, nicotinic, alpha polypeptide 4, [Score=250, Expect=7e-74]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=238, Expect=7e-71]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=238, Expect=9e-71]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=254, Expect=4e-77]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=231, Expect=2e-68]} {Smed: dd_Smed_v6_8486_0_1, dd_Smed_v6_8486_0_1, [RH, Score=560, Expect=0.0]} {RNA1509_15763} {RNA1310_13813} {RNA815_7852}

Mlig455_028532 {REF} {Length: 6717} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=182.9]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=125.6]} {Human: ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=262, Expect=1e-77]} {Mouse: ENSMUSG00000027577, Chrna4, cholinergic receptor, nicotinic, alpha polypeptide 4, [Score=250, Expect=3e-73]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=239, Expect=2e-70]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=238, Expect=4e-70]} {Dmel: FBgn0266347, nAChRalpha4, nicotinic Acetylcholine Receptor alpha4, [Score=255, Expect=1e-76]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=231, Expect=8e-68]} {Smed: dd_Smed_v6_8486_0_1, dd_Smed_v6_8486_0_1, [RH, Score=560, Expect=0.0]} {RNA1509_15763} {RNA1310_13813} {RNA815_7852}

Mlig455_064722 {REF} {Length: 349} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=26.8]} {Smed: dd_Smed_v6_8486_0_1, dd_Smed_v6_8486_0_1, [Score=75.9, Expect=3e-17]} {RNA1509_15763} {RNA1310_15286} {RNA815_7852}
6. MligTC455_46564 403 8.4 Mlig455_040238

Neo: -

Age: -

2.499 - - - 0.778 0.766 0.955 Mlig455_040238 {REF} {Length: 3013} {RNA1509_9486} {RNA1310_9854} {RNA815_15545}
7. MligTC455_22259 260 5.42 Mlig455_030218, Mlig455_039648

Neo: -

Age: -

CACNA2D4 2.419 - 0.720 - 0.727 0.972 -

Mlig455_030218 {REF} {Length: 920} {Pfam: SAP domain [PF02037.29, score=39.1]} {RNA1509_18097} {RNA1310_23148} {RNA815_801}

Mlig455_039648 {REF} {Length: 4984} {Pfam: VWA N-terminal [PF08399.13, score=86.4]; Neuronal voltage-dependent calcium channel alpha 2acd [PF08473.13, score=54.3]; von Willebrand factor type A domain [PF13768.8, score=35.2]; von Willebrand factor type A domain [PF00092.30, score=23.9]; von Willebrand factor type A domain [PF13519.8, score=22.7]} {Human: ENSG00000284953, CACNA2D4, calcium voltage-gated channel auxiliary subunit alpha2delta 4, [RH, Score=235, Expect=2e-65]; ENSG00000151062, CACNA2D4, calcium voltage-gated channel auxiliary subunit alpha2delta 4, [RH, Score=235, Expect=2e-65]} {Mouse: ENSMUSG00000041460, Cacna2d4, calcium channel, voltage-dependent, alpha 2/delta subunit 4, [Score=240, Expect=2e-64]; ENSMUSG00000021991, Cacna2d3, calcium channel, voltage-dependent, alpha2/delta subunit 3, [Score=233, Expect=3e-62]} {Dmel: FBgn0261041, stj, straightjacket, [RH, Score=362, Expect=1e-104]} {Celegans: WBGene00006772, unc-36, Voltage-dependent calcium channel unc-36, [RH, Score=210, Expect=6e-55]} {Smed: dd_Smed_v6_8926_0_1, dd_Smed_v6_8926_0_1, [RH, Score=449, Expect=3e-135]} {RNA1509_45954} {RNA1310_7077.1} {RNA815_9934.1}
8. MligTC455_41776 767 15.97 Mlig455_049379

Neo: -

Age: -

IQCB1 1.877 - - - 0.926 - 0.951 Mlig455_049379 {REF} {Length: 2348} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=30.0]} {Human: ENSG00000173226, IQCB1, IQ motif containing B1, [RH, Score=202, Expect=2e-56]} {Mouse: ENSMUSG00000022837, Iqcb1, IQ calmodulin-binding motif containing 1, [RH, Score=220, Expect=3e-63]} {Smed: dd_Smed_v6_11329_0_1, dd_Smed_v6_11329_0_1, [RH, Score=233, Expect=4e-68]} {RNA1509_36269, RNA1509_8893} {RNA1310_11108.1, RNA1509_36269, RNA1509_8893} {RNA1509_36269, RNA1509_8893, RNA815_4095.1}
9. MligTC455_37111 1709 35.61 Mlig455_015739, Mlig455_049445, Mlig455_049459

Neo: -

Age: logFC(26M/2M)=-0.249

Region-enriched R2: 1.162/0.04679

1.807 - - - 0.842 - 0.965

Mlig455_015739 {REF} {Length: 1115} {RNA1509_33493} {RNA1310_28591.1} {RNA815_13812.1}

Mlig455_049445 {REF} {Length: 1524} {RNA1509_21694, RNA1509_33493} {RNA1310_28591.1, RNA1509_21694, RNA1509_33493} {RNA1509_21694, RNA1509_33493, RNA815_13812.1}

Mlig455_049459 {REF} {Length: 2200} {RNA1509_21694} {RNA1310_28591.1} {RNA815_13812.1}
10. MligTC455_45407 363 7.56 Mlig455_010440

Neo: -

Age: logFC(26M/2M)=-0.344

ANXA4 1.762 - - - 0.806 - 0.956 Mlig455_010440 {REF} {Length: 2900} {TRANSSPLICED} {Pfam: Annexin [PF00191.22, score=92.7]; Fn3 associated [PF13287.8, score=23.3]; Chitobiase/beta-hexosaminidase C-terminal domain [PF13290.8, score=22.9]} {Human: ENSG00000196975, ANXA4, annexin A4, [Score=135, Expect=1e-34]; ENSG00000138279, ANXA7, annexin A7, [Score=135, Expect=2e-33]; ENSG00000197043, ANXA6, annexin A6, [Score=133, Expect=7e-32]; ENSG00000182718, ANXA2, annexin A2, [Score=132, Expect=3e-33]; ENSG00000122359, ANXA11, annexin A11, [Score=130, Expect=2e-31]} {Mouse: ENSMUSG00000029994, Anxa4, annexin A4, [Score=147, Expect=1e-38]} {Dmel: FBgn0030749, AnxB11, Annexin B11, [Score=131, Expect=4e-32]} {Celegans: WBGene00003589, nex-2, Annexin, [Score=118, Expect=5e-28]} {Smed: dd_Smed_v6_5798_0_1, dd_Smed_v6_5798_0_1, [Score=192, Expect=7e-52]} {RNA1509_12546, RNA1509_14199} {RNA1310_5065, RNA1509_12546, RNA1509_14199} {RNA1509_12546, RNA1509_14199, RNA815_285.1}
11. MligTC455_29770 150 3.12 Mlig455_013548, Mlig455_041433

Neo: -

Age: -

MAP3K19 1.76 - - - - 0.973 0.787

Mlig455_013548 {REF} {Length: 571} {NoTransDecoderORF} {RNA1509_6748} {RNA1310_95865} {RNA815_24422.1}

Mlig455_041433 {REF} {Length: 1974} {Pfam: Protein kinase domain [PF00069.27, score=69.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=55.3]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=84.0, Expect=3e-19]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=80.5, Expect=3e-18]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=70.1, Expect=8e-15]} {Celegans: WBGene00003144, max-2, Serine/threonine-protein kinase max-2, [Score=61.2, Expect=5e-12]} {Smed: dd_Smed_v6_2030_0_29, dd_Smed_v6_2030_0_29, [Score=75.1, Expect=3e-18]} {RNA1509_48626} {RNA1310_17852.1} {RNA815_25899}
12. MligTC455_46414 1658 34.54 Mlig455_057089

Neo: -

Age: logFC(26M/2M)=-0.221

OTOF 1.756 - 0.798 - - - 0.958 Mlig455_057089 {REF} {Length: 7426} {Pfam: C2 domain [PF00168.32, score=180.5]; FerB (NUC096) domain [PF08150.14, score=74.9]; Ferlin C-terminus [PF16165.7, score=61.5]} {Human: ENSG00000115155, OTOF, otoferlin, [Score=514, Expect=4e-149]} {Mouse: ENSMUSG00000062372, Otof, otoferlin, [Score=515, Expect=1e-149]} {Dmel: FBgn0266757, mfr, misfire, [Score=239, Expect=2e-66]} {Celegans: WBGene00001414, fer-1, Sperm vesicle fusion protein fer-1, [Score=127, Expect=7e-29]} {Smed: dd_Smed_v6_5915_0_1, dd_Smed_v6_5915_0_1, [Score=752, Expect=0.0]} {RNA1509_41457, RNA1509_6240} {RNA1310_364, RNA1509_41457} {RNA1509_41457, RNA815_373}
13. MligTC455_29169 108 2.25 Mlig455_002330

Neo: -

Age: Up-Down-Down

DNAH5 1.745 - - - - 0.952 0.793 Mlig455_002330 {REF} {Length: 14879} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=576.9]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=466.5]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=429.5]; Dynein heavy chain C-terminal domain [PF18199.3, score=313.2]; P-loop containing dynein motor region D4 [PF12780.9, score=303.1]; ATP-binding dynein motor region [PF12781.9, score=290.8]; P-loop containing dynein motor region [PF12775.9, score=229.8]; Dynein heavy chain AAA lid domain [PF18198.3, score=179.2]; Microtubule-binding stalk of dynein motor [PF12777.9, score=144.8]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=121.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=75.6]; Dynein heavy chain AAA lid domain [PF17852.3, score=70.5]; AAA+ lid domain [PF17857.3, score=60.9]; AAA ATPase domain [PF13191.8, score=21.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=21.3]; P-loop containing region of AAA domain [PF13555.8, score=20.3]} {Human: ENSG00000039139, DNAH5, dynein axonemal heavy chain 5, [RH, Score=6256, Expect=0.0]} {Mouse: ENSMUSG00000022262, Dnah5, dynein, axonemal, heavy chain 5, [RH, Score=6232, Expect=0.0]} {Dmel: FBgn0037726, CG9492, [RH, Score=5094, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=1294, Expect=0.0]} {Smed: dd_Smed_v6_4569_0_1, dd_Smed_v6_4569_0_1, [RH, Score=6936, Expect=0.0]} {RNA1509_39171, RNA1509_51275} {RNA1310_408, RNA1509_39171} {RNA1509_39171, RNA815_44.1}
14. MligTC455_46795 785 16.35 Mlig455_000535

Neo: -

Age: logFC(26M/2M)=-0.364

Region-enriched R2: 1.672/0.01916

HTR1B 1.739 - - - - 0.958 0.781 Mlig455_000535 {REF} {Length: 4573} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=255.2]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=53.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.4]; Family of unknown function (DUF5684) [PF18936.2, score=19.6]} {Human: ENSG00000135312, HTR1B, 5-hydroxytryptamine receptor 1B, [RH, Score=243, Expect=3e-75]} {Mouse: ENSMUSG00000021721, Htr1a, 5-hydroxytryptamine (serotonin) receptor 1A, [Score=251, Expect=3e-78]} {Dmel: FBgn0004573, 5-HT7, 5-hydroxytryptamine (serotonin) receptor 7, [RH, Score=276, Expect=2e-86]} {Celegans: WBGene00004780, ser-7, SERotonin/octopamine receptor family, [RH, Score=221, Expect=1e-66]} {Smed: dd_Smed_v6_5341_0_1, dd_Smed_v6_5341_0_1, [RH, Score=412, Expect=2e-140]} {RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1310_3896.1, RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1509_11749, RNA1509_13593, RNA1509_37815, RNA815_3010}
15. MligTC455_07422 104 2.17 Mlig455_059513

Neo: -

Age: -

SLC22A13 1.732 - - - 0.953 0.779 - Mlig455_059513 {REF} {Length: 3916} {Pfam: Sugar (and other) transporter [PF00083.26, score=103.6]; Major Facilitator Superfamily [PF07690.18, score=44.3]} {Human: ENSG00000172940, SLC22A13, solute carrier family 22 member 13, [Score=195, Expect=5e-53]; ENSG00000112499, SLC22A2, solute carrier family 22 member 2, [Score=189, Expect=4e-51]; ENSG00000146477, SLC22A3, solute carrier family 22 member 3, [Score=186, Expect=5e-50]} {Mouse: ENSMUSG00000023829, Slc22a1, solute carrier family 22 (organic cation transporter), member 1, [Score=189, Expect=4e-51]; ENSMUSG00000040966, Slc22a2, solute carrier family 22 (organic cation transporter), member 2, [Score=188, Expect=5e-51]; ENSMUSG00000074028, Slc22a13, solute carrier family 22 (organic cation transporter), member 13, [Score=186, Expect=4e-50]; ENSMUSG00000023828, Slc22a3, solute carrier family 22 (organic cation transporter), member 3, [Score=184, Expect=2e-49]} {Dmel: FBgn0086365, Orct2, Organic cation transporter 2, [Score=206, Expect=4e-57]} {Celegans: WBGene00022348, Y82E9BR.16, [Score=167, Expect=1e-43]} {Smed: dd_Smed_v6_11120_0_1, dd_Smed_v6_11120_0_1, [RH, Score=205, Expect=2e-57]} {RNA1509_56460} {RNA1310_33118, RNA1509_56460} {RNA1509_56460, RNA815_21922}
16. MligTC455_50685 443 9.22 Mlig455_008930

Neo: -

Age: Up-Down-Down

LRRK2 1.729 - - - 0.777 - 0.952 Mlig455_008930 {REF} {Length: 12042} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=151.5]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=75.1]; TIR domain [PF13676.8, score=67.0]; Ras family [PF00071.24, score=44.4]; Leucine rich repeat [PF13855.8, score=39.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=24.7]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=158, Expect=1e-37]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=161, Expect=9e-39]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=146, Expect=3e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=122, Expect=5e-27]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=714, Expect=0.0]} {RNA1509_2407, RNA1509_24338, RNA1509_49350} {RNA1310_77.1, RNA1509_2407, RNA1509_24338, RNA1509_49350} {RNA1509_2407, RNA1509_24338, RNA1509_49350, RNA815_489}
17. MligTC455_32420 549 11.44 Mlig455_039348

Neo: -

Age: logFC(26M/2M)=-0.499

NWD2 1.726 - - - 0.774 - 0.952 Mlig455_039348 {REF} {Length: 8236} {TRANSSPLICED} {Pfam: NACHT domain [PF05729.14, score=43.5]; AAA ATPase domain [PF13191.8, score=38.9]; Dpy-30 motif [PF05186.15, score=31.9]; AAA domain [PF13401.8, score=20.4]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=445, Expect=1e-127]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=438, Expect=1e-125]} {Dmel: FBgn0038397, CG10185, [Score=536, Expect=2e-159]} {Celegans: WBGene00020254, T05C3.2, [Score=549, Expect=1e-163]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=295, Expect=2e-80]} {RNA1509_3054, RNA1509_32303, RNA1509_34526, RNA1509_42986} {RNA1310_425, RNA1509_3054, RNA1509_32303, RNA1509_34526, RNA1509_42986} {RNA1509_3054, RNA1509_32303, RNA1509_34526, RNA1509_42986, RNA815_139.1}
18. MligTC455_44021 681 14.19 Mlig455_027402

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.474

STYXL1 1.725 - - - 0.769 - 0.956 Mlig455_027402 {REF} {Length: 1736} {Pfam: Dual specificity phosphatase, catalytic domain [PF00782.22, score=65.4]; Rhodanese-like domain [PF00581.22, score=29.2]} {Human: ENSG00000127952, STYXL1, serine/threonine/tyrosine interacting like 1, [RH, Score=196, Expect=2e-60]} {Mouse: ENSMUSG00000019178, Styxl1, serine/threonine/tyrosine interacting-like 1, [RH, Score=188, Expect=1e-57]} {Dmel: FBgn0039742, CG15528, [Score=52.8, Expect=6e-08]} {Celegans: WBGene00017428, F13D11.3, [Score=57.8, Expect=5e-10]} {Smed: dd_Smed_v6_11358_0_1, dd_Smed_v6_11358_0_1, [RH, Score=251, Expect=8e-83]} {RNA1509_4392} {RNA1310_10767.2, RNA1509_4392} {RNA1509_4392, RNA815_8325.1}
19. MligTC455_31388 302 6.3 Mlig455_042897

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=1.156

Region-enriched R4: 2.173/0.03395

DZIP3 1.724 - - - 0.968 - 0.756 Mlig455_042897 {REF} {Length: 4534} {Pfam: DZIP3/ hRUL138-like HEPN [PF18738.3, score=66.1]; NACHT domain [PF05729.14, score=54.1]; Caspase recruitment domain [PF00619.23, score=35.9]} {Human: ENSG00000198919, DZIP3, DAZ interacting zinc finger protein 3, [RH, Score=60.1, Expect=2e-08]} {Mouse: ENSMUSG00000116073, LT629150.1, NLR family, pyrin domain containing 1B, [RH, Score=52.4, Expect=5e-06]} {Smed: dd_Smed_v6_11157_0_1, dd_Smed_v6_11157_0_1, [RH, Score=788, Expect=0.0]} {RNA1509_1974} {RNA1310_1220} {RNA815_423}
20. MligTC455_20272 92 1.92 Mlig455_026087

Neo: -

Age: Down-Up-Down

1.718 - - - 0.747 0.971 - Mlig455_026087 {REF} {Length: 2788} {TRANSSPLICED} {RNA1509_16686, RNA1509_45662} {RNA1310_16986, RNA1509_45662} {RNA1509_45662, RNA815_5991}
21. MligTC455_24222 490 10.21 Mlig455_037213

Neo: -

Age: logFC(26M/2M)=0.272

CFAP36 1.717 - - - - 0.767 0.950 Mlig455_037213 {REF} {Length: 3654} {Pfam: The ARF-like 2 binding protein BART [PF11527.10, score=79.0]} {Human: ENSG00000163001, CFAP36, cilia and flagella associated protein 36, [RH, Score=98.2, Expect=2e-22]} {Mouse: ENSMUSG00000020462, Cfap36, cilia and flagella associated protein 36, [RH, Score=97.8, Expect=2e-22]} {Dmel: FBgn0038170, CG14367, [RH, Score=75.9, Expect=3e-15]} {Celegans: WBGene00022435, cfap-36, Cilia- and flagella-associated protein 36, [RH, Score=87.8, Expect=1e-18]} {RNA1509_40996} {RNA1310_7183.2} {RNA815_12471}
22. MligTC455_48100 335 6.97 Mlig455_018371

Neo: -

Age: logFC(26M/2M)=-0.384

LRRC71 1.708 - - - 0.742 - 0.966 Mlig455_018371 {REF} {Length: 2302} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=67.4]; Leucine Rich repeats (2 copies) [PF12799.9, score=26.9]; Leucine Rich Repeat [PF00560.35, score=24.2]} {Human: ENSG00000160838, LRRC71, leucine rich repeat containing 71, [RH, Score=202, Expect=1e-57]} {Mouse: ENSMUSG00000023084, Lrrc71, leucine rich repeat containing 71, [RH, Score=200, Expect=9e-57]} {Smed: dd_Smed_v6_12043_0_2, dd_Smed_v6_12043_0_2, [RH, Score=224, Expect=3e-67]} {RNA1509_21151, RNA1509_55854, RNA1509_5738} {RNA1310_2341.1, RNA1509_21151, RNA1509_55854, RNA1509_5738} {RNA1509_21151, RNA1509_55854, RNA1509_5738, RNA815_677.1}
23. MligTC455_40849 213 4.44 Mlig455_030783, Mlig455_047791

Neo: -

Age: logFC(26M/2M)=-0.387

1.703 - - - 0.973 - 0.730

Mlig455_030783 {REF} {Length: 1480} {RNA1310_22569} {RNA815_10132.1}

Mlig455_047791 {REF} {Length: 1906} {NoTransDecoderORF} {RNA1509_49832} {RNA1310_22569} {RNA815_10132.1}
24. MligTC455_52589 87 1.82 Mlig455_059209

Neo: -

Age: -

1.684 - - 0.732 - 0.952 - Mlig455_059209 {REF} {Length: 2113} {NoTransDecoderORF} {RNA1509_49308} {RNA1310_53726} {RNA815_13935.1}
25. MligTC455_28164 136 2.83 Mlig455_045835

Neo: -

Age: -

LRRC9 1.671 - - - - 0.958 0.713 Mlig455_045835 {REF} {Length: 10638} {Pfam: Leucine-rich repeat [PF14580.8, score=159.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=149.0]; Leucine rich repeat [PF13855.8, score=111.3]} {Human: ENSG00000131951, LRRC9, leucine rich repeat containing 9, [RH, Score=436, Expect=2e-129]} {Mouse: ENSMUSG00000021090, Lrrc9, leucine rich repeat containing 9, [RH, Score=639, Expect=0.0]} {Dmel: FBgn0039728, CG7896, [Score=74.7, Expect=6e-13]} {Celegans: WBGene00020266, T05H4.3, [RH, Score=80.1, Expect=8e-15]} {Smed: dd_Smed_v6_14851_0_1, dd_Smed_v6_14851_0_1, [RH, Score=369, Expect=2e-108]} {RNA1509_22179, RNA1509_44615} {RNA1310_1731, RNA1509_44615} {RNA1509_44615, RNA815_589.1}
26. MligTC455_47621 1270 26.46 Mlig455_010483

Neo: -

Age: -

1.669 - - 0.718 - - 0.951 Mlig455_010483 {REF} {Length: 2702} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=18.8]} {RNA1509_3407, RNA1509_9846} {RNA1310_8526.1, RNA1509_3407, RNA1509_9846} {RNA1509_3407, RNA1509_9846, RNA815_3060}
27. MligTC455_25620 44 0.92 Mlig455_026905

Neo: -

Age: Down-Up-Down

SDCBP 0.979 - - - - 0.979 - Mlig455_026905 {REF} {Length: 3278} {Pfam: PDZ domain [PF00595.26, score=78.4]; PDZ domain [PF17820.3, score=53.7]; PDZ domain [PF13180.8, score=40.6]} {Human: ENSG00000137575, SDCBP, syndecan binding protein, [Score=53.9, Expect=2e-07]; ENSG00000125775, SDCBP2, syndecan binding protein 2, [Score=51.6, Expect=1e-06]} {Mouse: ENSMUSG00000030838, Ush1c, USH1 protein network component harmonin, [Score=56.2, Expect=7e-08]; ENSMUSG00000028249, Sdcbp, syndecan binding protein, [Score=55.8, Expect=1e-08]; ENSMUSG00000027456, Sdcbp2, syndecan binding protein (syntenin) 2, [Score=53.9, Expect=2e-07]} {Dmel: FBgn0029835, CG5921, [Score=68.2, Expect=1e-11]} {Smed: dd_Smed_v6_11951_0_1, dd_Smed_v6_11951_0_1, [Score=175, Expect=2e-49]} {RNA1509_46792} {RNA1310_11662.1} {RNA815_21959}
28. MligTC455_46602 231 4.8 Mlig455_024992

Neo: -

Age: logFC(26M/2M)=0.375

PTPN6 0.963 - - - - 0.963 - Mlig455_024992 {REF} {Length: 2678} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=216.4]; SH2 domain [PF00017.26, score=23.1]} {Human: ENSG00000111679, PTPN6, protein tyrosine phosphatase, non-receptor type 6, [Score=203, Expect=2e-57]; ENSG00000179295, PTPN11, protein tyrosine phosphatase, non-receptor type 11, [Score=201, Expect=8e-57]} {Mouse: ENSMUSG00000004266, Ptpn6, protein tyrosine phosphatase, non-receptor type 6, [Score=214, Expect=2e-61]} {Dmel: FBgn0261985, Ptpmeg, Protein tyrosine phosphatase Meg, [Score=149, Expect=1e-37]} {Celegans: WBGene00004214, ptp-2, Tyrosine-protein phosphatase non-receptor type ptp-2, [Score=184, Expect=2e-50]} {Smed: dd_Smed_v6_5785_0_1, dd_Smed_v6_5785_0_1, [Score=214, Expect=1e-61]} {RNA1509_17439} {RNA1310_10787.1, RNA1509_17439} {RNA1509_17439, RNA815_8481}
29. MligTC455_41311 325 6.78 Mlig455_046105

Neo: -

Age: -

SPSB3 0.961 - - - 0.961 - - Mlig455_046105 {REF} {Length: 1490} {TRANSSPLICED} {Pfam: SPRY domain [PF00622.30, score=37.7]} {Human: ENSG00000162032, SPSB3, splA/ryanodine receptor domain and SOCS box containing 3, [RH, Score=200, Expect=5e-60]} {Mouse: ENSMUSG00000024160, Spsb3, splA/ryanodine receptor domain and SOCS box containing 3, [RH, Score=205, Expect=2e-62]} {Dmel: FBgn0036549, CG10516, [RH, Score=133, Expect=2e-35]} {RNA1509_29153} {RNA1310_12694.1} {RNA815_7666}
30. MligTC455_08478 59 1.22 Mlig455_009785

Neo: -

Age: -

0.959 - - - - 0.959 - Mlig455_009785 {REF} {Length: 348} {NoTransDecoderORF}
31. MligTC455_22634 204 4.26 Mlig455_027696

Neo: -

Age: Down-Down-Up

CCDC92 0.957 - - - - - 0.957 Mlig455_027696 {REF} {Length: 1900} {TRANSSPLICED} {Pfam: Coiled-coil domain of unknown function [PF14916.8, score=67.5]} {Human: ENSG00000275035, CCDC92, coiled-coil domain containing 92, [RH, Score=57.8, Expect=6e-09]; ENSG00000119242, CCDC92, coiled-coil domain containing 92, [RH, Score=57.8, Expect=6e-09]} {Mouse: ENSMUSG00000037979, Ccdc92, coiled-coil domain containing 92, [RH, Score=53.1, Expect=1e-07]} {Smed: dd_Smed_v6_15609_0_1, dd_Smed_v6_15609_0_1, [RH, Score=65.5, Expect=6e-12]} {RNA1310_28822} {RNA815_31004}
32. MligTC455_51189 50 1.04 Mlig455_009762

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.901

ETV1 0.957 - - - - 0.957 - Mlig455_009762 {REF} {Length: 2915} {Pfam: Ets-domain [PF00178.24, score=116.1]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.9]} {Human: ENSG00000006468, ETV1, ETS variant 1, [RH, Score=196, Expect=6e-55]; ENSG00000244405, ETV5, ETS variant 5, [RH, Score=195, Expect=3e-54]; ENSG00000175832, ETV4, ETS variant 4, [RH, Score=193, Expect=5e-54]} {Mouse: ENSMUSG00000013089, Etv5, ets variant 5, [RH, Score=196, Expect=1e-54]; ENSMUSG00000004151, Etv1, ets variant 1, [RH, Score=195, Expect=5e-55]; ENSMUSG00000017724, Etv4, ets variant 4, [RH, Score=193, Expect=6e-54]} {Dmel: FBgn0039225, Ets96B, [RH, Score=186, Expect=3e-50]} {Celegans: WBGene00016600, ets-5, ETS class transcription factor, [Score=121, Expect=2e-31]} {Smed: dd_Smed_v6_14712_0_1, dd_Smed_v6_14712_0_1, [RH, Score=169, Expect=7e-46]} {RNA1310_33762} {RNA815_60843}
33. MligTC455_15671 88 1.84 Mlig455_059458

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.370

Region-enriched R4: 4.705/0.00509

KIAA0895L 0.955 - - - - - 0.955 Mlig455_059458 {REF} {Length: 3483} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF1704) [PF08014.13, score=37.3]} {Human: ENSG00000196123, KIAA0895L, KIAA0895 like, [RH, Score=151, Expect=4e-40]; ENSG00000164542, KIAA0895, KIAA0895, [RH, Score=150, Expect=1e-39]} {Mouse: ENSMUSG00000014837, 4931428F04Rik, RIKEN cDNA 4931428F04 gene, [RH, Score=156, Expect=4e-42]} {Smed: dd_Smed_v6_103892_0_1, dd_Smed_v6_103892_0_1, [RH, Score=98.6, Expect=3e-25]} {RNA1509_47713, RNA1509_49841} {RNA1310_17536.1, RNA1509_47713, RNA1509_49841} {RNA1509_47713, RNA1509_49841, RNA815_7463.1}
34. MligTC455_28911 375 7.82 Mlig455_065714

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.597

Region-enriched R2: 2.396/0.00344

0.955 - - - - 0.955 - Mlig455_065714 {REF} {Length: 10556} {TRANSSPLICED} {Pfam: gag-polyprotein putative aspartyl protease [PF13975.8, score=35.4]; Aspartyl protease [PF13650.8, score=29.7]; Retroviral aspartyl protease [PF00077.22, score=27.6]; Zinc knuckle [PF00098.25, score=20.4]} {Smed: dd_Smed_v6_16336_0_1, dd_Smed_v6_16336_0_1, [Score=63.2, Expect=5e-10]} {RNA1509_6522} {RNA1310_59.1} {RNA815_29.1}
35. MligTC455_33496 155 3.23 Mlig455_004570, Mlig455_004580, Mlig455_064765

Neo: -

Age: -

CNBD2 0.952 - - - - 0.952 -

Mlig455_004570 {REF} {Length: 2563} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=72.5]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [Score=66.6, Expect=5e-11]} {Mouse: ENSMUSG00000038085, Cnbd2, cyclic nucleotide binding domain containing 2, [Score=60.1, Expect=6e-09]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [Score=57.0, Expect=2e-08]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=53.5, Expect=2e-07]} {Smed: dd_Smed_v6_19613_0_1, dd_Smed_v6_19613_0_1, [Score=198, Expect=4e-57]} {RNA1509_46945} {RNA1310_3543} {RNA815_8743}

Mlig455_004580 {REF} {Length: 2984} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=77.5]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [Score=67.0, Expect=5e-11]} {Mouse: ENSMUSG00000038085, Cnbd2, cyclic nucleotide binding domain containing 2, [Score=60.1, Expect=5e-09]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [Score=57.4, Expect=1e-08]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=53.5, Expect=2e-07]} {Smed: dd_Smed_v6_19613_0_1, dd_Smed_v6_19613_0_1, [Score=196, Expect=2e-56]} {RNA1509_46945} {RNA1310_3543} {RNA815_8743}

Mlig455_064765 {REF} {Length: 3465} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=77.5]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [Score=67.0, Expect=4e-11]} {Mouse: ENSMUSG00000038085, Cnbd2, cyclic nucleotide binding domain containing 2, [Score=60.1, Expect=5e-09]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [Score=57.4, Expect=1e-08]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=53.5, Expect=2e-07]} {Smed: dd_Smed_v6_19613_0_1, dd_Smed_v6_19613_0_1, [Score=196, Expect=2e-56]} {RNA1509_46945} {RNA1310_3543} {RNA815_8743}
36. MligTC455_50147 76 1.59 Mlig455_046359

Neo: -

Age: -

0.951 - - - 0.951 - - Mlig455_046359 {REF} {Length: 1425} {RNA1509_15977} {RNA1310_48391} {RNA815_20870.1}

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