Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_32739 | 3488 | 72.67 | Mlig455_000131 | Neo: Neoblast, stringent Age: logFC(26M/2M)=0.180 Region-enriched R5: 1.541/0.00001 Regeneration-upregulated BL: 1.860 Regeneration-enriched BL: 1.860 |
RRM1 | Mlig455_000131 {REF} {Length: 3338} {Pfam: Ribonucleotide reductase, barrel domain [PF02867.17, score=612.4]; Ribonucleotide reductase, all-alpha domain [PF00317.23, score=78.9]; ATP cone domain [PF03477.18, score=63.3]} {Human: ENSG00000167325, RRM1, ribonucleotide reductase catalytic subunit M1, [RH, Score=1181, Expect=0.0]} {Mouse: ENSMUSG00000030978, Rrm1, ribonucleotide reductase M1, [RH, Score=1188, Expect=0.0]} {Dmel: FBgn0011703, RnrL, Ribonucleoside diphosphate reductase large subunit, [RH, Score=1140, Expect=0.0]} {Celegans: WBGene00004391, rnr-1, Ribonucleoside-diphosphate reductase large subunit, [RH, Score=1118, Expect=0.0]} {Smed: dd_Smed_v6_1651_0_1, dd_Smed_v6_1651_0_1, [RH, Score=1077, Expect=0.0]} {RNA1509_1369, RNA1509_15599, RNA1509_45206} {RNA1310_3739.1, RNA1509_1369, RNA1509_15599, RNA1509_45206} {RNA1509_1369, RNA1509_15599, RNA1509_45206, RNA815_1323} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.344 | 6.233 | 0.60623 | 1.00000 | |
RegionR2 | -0.852 | 6.233 | 0.05504 | 0.28107 | |
RegionR3 | -0.04 | 6.233 | 0.91338 | 1.00000 | |
RegionR4 | 0.156 | 6.233 | 0.67957 | 0.97416 | |
RegionR5 | 1.541 | 6.233 | 0.00000 | 0.00001 | |
RegionR6 | 0.48 | 6.233 | 0.15433 | 0.70079 | |
RegionR7 | 0.245 | 6.233 | 0.52784 | 1.00000 | |
RegionR8 | -1.187 | 6.233 | 0.03738 | 0.37970 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 1.083 | 6.233 | 0.17459 | 0.91661 | |
RegenerationR2 | 0.205 | 6.233 | 0.63602 | 0.92984 | |
RegenerationR3 | 1.158 | 6.233 | 0.00663 | 0.14776 | |
RegenerationR4 | 0.839 | 6.233 | 0.04825 | 0.35409 | |
RegenerationR5 | 0.35 | 6.233 | 0.38482 | 0.78896 | |
RegenerationR6 | 1.573 | 6.233 | 0.00018 | 0.01258 | |
RegenerationBL | 1.86 | 6.233 | 0.00000 | 0.00014 | Specific for BL: 1.860 |
RegenerationTP | 1.135 | 6.233 | 0.01570 | 0.21476 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_32739 | 3488 | 72.67 | Mlig455_000131 | Neo: Neoblast, stringent Age: logFC(26M/2M)=0.180 Region-enriched R5: 1.541/0.00001 Regeneration-upregulated BL: 1.860 Regeneration-enriched BL: 1.860 |
RRM1 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_000131 {REF} {Length: 3338} {Pfam: Ribonucleotide reductase, barrel domain [PF02867.17, score=612.4]; Ribonucleotide reductase, all-alpha domain [PF00317.23, score=78.9]; ATP cone domain [PF03477.18, score=63.3]} {Human: ENSG00000167325, RRM1, ribonucleotide reductase catalytic subunit M1, [RH, Score=1181, Expect=0.0]} {Mouse: ENSMUSG00000030978, Rrm1, ribonucleotide reductase M1, [RH, Score=1188, Expect=0.0]} {Dmel: FBgn0011703, RnrL, Ribonucleoside diphosphate reductase large subunit, [RH, Score=1140, Expect=0.0]} {Celegans: WBGene00004391, rnr-1, Ribonucleoside-diphosphate reductase large subunit, [RH, Score=1118, Expect=0.0]} {Smed: dd_Smed_v6_1651_0_1, dd_Smed_v6_1651_0_1, [RH, Score=1077, Expect=0.0]} {RNA1509_1369, RNA1509_15599, RNA1509_45206} {RNA1310_3739.1, RNA1509_1369, RNA1509_15599, RNA1509_45206} {RNA1509_1369, RNA1509_15599, RNA1509_45206, RNA815_1323} |
2. | MligTC455_36725 | 2025 | 42.18 | Mlig455_067648 | Neo: Neoblast Age: - Region-enriched R4: 1.585/0.00020 |
4.114 | - | 0.779 | 0.755 | 0.974 | 0.897 | 0.709 | Mlig455_067648 {REF} {Length: 504} {NoTransDecoderORF} {RNA1509_13962, RNA1509_42268} {RNA1310_27652, RNA1509_42268} {RNA1509_42268, RNA815_13775} | |
3. | MligTC455_36726 | 1992 | 41.49 | Mlig455_067649 | Neo: Irradiation Age: logFC(26M/2M)=0.330 Region-enriched R4: 1.538/0.00058 |
DUT | 4.108 | - | 0.786 | 0.760 | 0.975 | 0.874 | 0.713 | Mlig455_067649 {REF} {Length: 1108} {TRANSSPLICED} {Pfam: dUTPase [PF00692.21, score=135.4]} {Human: ENSG00000128951, DUT, deoxyuridine triphosphatase, [RH, Score=176, Expect=9e-57]} {Mouse: ENSMUSG00000027203, Dut, deoxyuridine triphosphatase, [RH, Score=173, Expect=1e-55]} {Dmel: FBgn0250837, dUTPase, Deoxyuridine triphosphatase, [RH, Score=172, Expect=4e-55]} {Celegans: WBGene00010609, dut-1, DeoxyUTPase; Deoxyuridinetriphosphatase, [RH, Score=160, Expect=5e-47]} {Smed: dd_Smed_v6_2921_0_1, dd_Smed_v6_2921_0_1, [RH, Score=184, Expect=3e-60]} {RNA1509_13962, RNA1509_43560, RNA1509_54784, RNA1509_60066} {RNA1310_27652, RNA1509_13962, RNA1509_43560, RNA1509_54784, RNA1509_60066} {RNA1509_13962, RNA1509_43560, RNA1509_54784, RNA1509_60066, RNA815_13775} |
4. | MligTC455_21931 | 2712 | 56.5 | Mlig455_043139 | Neo: Neoblast, stringent Age: logFC(26M/2M)=0.391 Region-enriched R5: 1.059/0.00122 Regeneration-enriched BL: 2.317 |
RRM2 | 3.379 | 0.806 | - | - | 0.847 | 0.775 | 0.951 | Mlig455_043139 {REF} {Length: 1921} {TRANSSPLICED} {Pfam: Ribonucleotide reductase, small chain [PF00268.23, score=380.0]} {Human: ENSG00000171848, RRM2, ribonucleotide reductase regulatory subunit M2, [RH, Score=527, Expect=0.0]; ENSG00000048392, RRM2B, ribonucleotide reductase regulatory TP53 inducible subunit M2B, [RH, Score=512, Expect=0.0]} {Mouse: ENSMUSG00000020649, Rrm2, ribonucleotide reductase M2, [RH, Score=531, Expect=0.0]; ENSMUSG00000022292, Rrm2b, ribonucleotide reductase M2 B (TP53 inducible), [RH, Score=509, Expect=0.0]} {Dmel: FBgn0011704, RnrS, Ribonucleoside diphosphate reductase small subunit, [RH, Score=530, Expect=0.0]} {Celegans: WBGene00004392, rnr-2, Ribonucleoside-diphosphate reductase small chain, [RH, Score=477, Expect=3e-169]} {Smed: dd_Smed_v6_2286_0_1, dd_Smed_v6_2286_0_1, [RH, Score=454, Expect=3e-161]} {RNA1509_16023, RNA1509_55631, RNA1509_6910, RNA1509_8818} {RNA1310_21187.1, RNA1509_16023, RNA1509_55631, RNA1509_6910} {RNA1509_16023, RNA1509_55631, RNA1509_6910, RNA815_4852.2} |
5. | MligTC455_36654 | 2861 | 59.61 | Mlig455_054150 | Neo: Neoblast, stringent Age: logFC(26M/2M)=0.371 Region-specific R5: 2.958 Region-enriched R5: 2.877/0.00000 |
3.347 | 0.863 | - | 0.764 | 0.954 | 0.766 | - | Mlig455_054150 {REF} {Length: 1361} {TRANSSPLICED} {Pfam: Stathmin family [PF00836.21, score=26.4]} {RNA1509_18964} {RNA1310_24170.1} {RNA815_9667} | |
6. | MligTC455_30322 | 5171 | 107.74 | Mlig455_061511, Mlig455_070649 | Neo: - Age: logFC(26M/2M)=0.353 Region-enriched R5: 1.516/0.02214 |
ALDH18A1 | 2.433 | - | 0.733 | - | 0.747 | 0.953 | - | Mlig455_061511 {REF} {Length: 697} {Pfam: Amino acid kinase family [PF00696.30, score=138.7]; Aldehyde dehydrogenase family [PF00171.24, score=57.0]} {Human: ENSG00000059573, ALDH18A1, aldehyde dehydrogenase 18 family member A1, [RH, Score=852, Expect=0.0]} {Mouse: ENSMUSG00000025007, Aldh18a1, aldehyde dehydrogenase 18 family, member A1, [RH, Score=857, Expect=0.0]} {Dmel: FBgn0037146, CG7470, [RH, Score=815, Expect=0.0]} {Celegans: WBGene00011938, alh-13, Probable delta-1-pyrroline-5-carboxylate synthase Glutamate 5-kinase Gamma-glutamyl phosphate reductase, [RH, Score=811, Expect=0.0]} {Smed: dd_Smed_v6_1060_0_1, dd_Smed_v6_1060_0_1, [RH, Score=916, Expect=0.0]} {RNA1509_1671} {RNA1310_2413} {RNA815_1917} Mlig455_070649 {REF} {Length: 925} {NoTransDecoderORF} {RNA1509_1671} {RNA1310_2413} {RNA815_1917} |
7. | MligTC455_30321 | 2622 | 54.63 | Mlig455_029593 | Neo: - Age: - Region-enriched R5: 1.544/0.02165 |
ALDH18A1 | 2.423 | - | 0.725 | - | 0.746 | 0.952 | - | Mlig455_029593 {REF} {Length: 2864} {TRANSSPLICED} {Pfam: Amino acid kinase family [PF00696.30, score=112.0]; Aldehyde dehydrogenase family [PF00171.24, score=71.4]} {Human: ENSG00000059573, ALDH18A1, aldehyde dehydrogenase 18 family member A1, [Score=778, Expect=0.0]} {Mouse: ENSMUSG00000025007, Aldh18a1, aldehyde dehydrogenase 18 family, member A1, [Score=781, Expect=0.0]} {Dmel: FBgn0037146, CG7470, [Score=761, Expect=0.0]} {Celegans: WBGene00011938, alh-13, Probable delta-1-pyrroline-5-carboxylate synthase Glutamate 5-kinase Gamma-glutamyl phosphate reductase, [Score=746, Expect=0.0]} {Smed: dd_Smed_v6_1060_0_1, dd_Smed_v6_1060_0_1, [Score=845, Expect=0.0]} {RNA1509_15292, RNA1509_16047, RNA1509_2611} {RNA1310_2413, RNA1509_15292, RNA1509_16047} {RNA1509_15292, RNA1509_16047, RNA815_1917} |
8. | MligTC455_30075 | 760 | 15.84 | Mlig455_010637, Mlig455_010725 | Neo: Neoblast, stringent Age: - Region-enriched R5: 1.545/0.00357 |
MCM6 | 1.849 | 0.894 | 0.955 | - | - | - | - | Mlig455_010637 {REF} {Length: 5506} {Pfam: MCM P-loop domain [PF00493.25, score=325.2]; MCM OB domain [PF17207.5, score=124.3]; MCM6 C-terminal winged-helix domain [PF18263.3, score=96.2]; MCM AAA-lid domain [PF17855.3, score=87.7]; MCM N-terminal domain [PF14551.8, score=60.7]; Magnesium chelatase, subunit ChlI [PF01078.23, score=31.9]; ATPase family associated with various cellular activities (AAA) [PF07726.13, score=25.0]; AAA domain (dynein-related subfamily) [PF07728.16, score=20.5]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.4]; Sigma-54 interaction domain [PF00158.28, score=18.9]} {Human: ENSG00000076003, MCM6, minichromosome maintenance complex component 6, [RH, Score=879, Expect=0.0]} {Mouse: ENSMUSG00000026355, Mcm6, minichromosome maintenance complex component 6, [RH, Score=868, Expect=0.0]} {Dmel: FBgn0025815, Mcm6, Minichromosome maintenance 6, [RH, Score=852, Expect=0.0]} {Celegans: WBGene00003158, mcm-6, DNA replication licensing factor mcm-6, [RH, Score=747, Expect=0.0]} {Smed: dd_Smed_v6_2682_0_1, dd_Smed_v6_2682_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_39578, RNA1509_4924, RNA1509_51000, RNA1509_9397} {RNA1310_1781.1, RNA1509_39578, RNA1509_4924, RNA1509_51000, RNA1509_9397} {RNA1509_39578, RNA1509_4924, RNA1509_51000, RNA1509_9397, RNA815_909} Mlig455_010725 {REF} {Length: 1016} {NoTransDecoderORF} {RNA1509_9397} {RNA1310_1781.1} {RNA815_24229.1} |
9. | MligTC455_44116 | 15886 | 330.96 | Mlig455_070259 | Neo: - Age: logFC(26M/2M)=-0.821 Region-enriched R3: 1.626/0.01191 |
BHMT | 0.963 | - | - | - | - | 0.963 | - | Mlig455_070259 {REF} {Length: 1926} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=168.1]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=562, Expect=0.0]} {Mouse: ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=570, Expect=0.0]; ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=570, Expect=0.0]} {Celegans: WBGene00010988, metr-1, Probable methionine synthase, [Score=52.4, Expect=5e-07]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=578, Expect=0.0]} {RNA1509_1011, RNA1509_1309, RNA1509_300, RNA1509_6942} {RNA1310_16129.1, RNA1509_1011, RNA1509_1309, RNA1509_300, RNA1509_6942} {RNA1509_1011, RNA1509_1309, RNA1509_300, RNA1509_6942, RNA815_5900.1} |
10. | MligTC455_43846 | 3542 | 73.79 | Mlig455_054802 | Neo: - Age: - Region-enriched R4: 1.013/0.00780 Regeneration-upregulated BL: 1.109 Regeneration-enriched BL: 1.109 |
PSMC4 | 0.951 | - | - | - | - | 0.951 | - | Mlig455_054802 {REF} {Length: 1813} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=146.8]; Proteasomal ATPase OB C-terminal domain [PF16450.7, score=46.4]; AAA+ lid domain [PF17862.3, score=37.9]; AAA domain (Cdc48 subfamily) [PF07724.16, score=33.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=31.7]; AAA ATPase domain [PF13191.8, score=25.0]; AAA domain [PF13401.8, score=22.0]; AAA domain [PF13238.8, score=21.2]; Protein of unknown function (DUF815) [PF05673.15, score=20.9]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=20.6]; AAA domain [PF13521.8, score=19.4]; Magnesium chelatase, subunit ChlI [PF01078.23, score=18.7]; TIP49 P-loop domain [PF06068.15, score=18.0]} {Human: ENSG00000013275, PSMC4, proteasome 26S subunit, ATPase 4, [RH, Score=716, Expect=0.0]; ENSG00000281221, PSMC4, proteasome 26S subunit, ATPase 4, [RH, Score=716, Expect=0.0]} {Mouse: ENSMUSG00000030603, Psmc4, proteasome (prosome, macropain) 26S subunit, ATPase, 4, [RH, Score=715, Expect=0.0]} {Dmel: FBgn0028686, Rpt3, Regulatory particle triple-A ATPase 3, [RH, Score=702, Expect=0.0]} {Celegans: WBGene00004503, rpt-3, Probable 26S protease regulatory subunit 6B, [RH, Score=629, Expect=0.0]} {Smed: dd_Smed_v6_1279_0_1, dd_Smed_v6_1279_0_1, [RH, Score=695, Expect=0.0]} {RNA1509_2743, RNA1509_41659} {RNA1310_15862, RNA1509_2743, RNA1509_41659} {RNA1509_2743, RNA1509_41659, RNA815_6256.1} |