Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_43846 | 3542 | 73.79 | Mlig455_054802 | Neo: - Age: - Region-enriched R4: 1.013/0.00780 Regeneration-upregulated BL: 1.109 Regeneration-enriched BL: 1.109 |
PSMC4 | Mlig455_054802 {REF} {Length: 1813} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=146.8]; Proteasomal ATPase OB C-terminal domain [PF16450.7, score=46.4]; AAA+ lid domain [PF17862.3, score=37.9]; AAA domain (Cdc48 subfamily) [PF07724.16, score=33.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=31.7]; AAA ATPase domain [PF13191.8, score=25.0]; AAA domain [PF13401.8, score=22.0]; AAA domain [PF13238.8, score=21.2]; Protein of unknown function (DUF815) [PF05673.15, score=20.9]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=20.6]; AAA domain [PF13521.8, score=19.4]; Magnesium chelatase, subunit ChlI [PF01078.23, score=18.7]; TIP49 P-loop domain [PF06068.15, score=18.0]} {Human: ENSG00000013275, PSMC4, proteasome 26S subunit, ATPase 4, [RH, Score=716, Expect=0.0]; ENSG00000281221, PSMC4, proteasome 26S subunit, ATPase 4, [RH, Score=716, Expect=0.0]} {Mouse: ENSMUSG00000030603, Psmc4, proteasome (prosome, macropain) 26S subunit, ATPase, 4, [RH, Score=715, Expect=0.0]} {Dmel: FBgn0028686, Rpt3, Regulatory particle triple-A ATPase 3, [RH, Score=702, Expect=0.0]} {Celegans: WBGene00004503, rpt-3, Probable 26S protease regulatory subunit 6B, [RH, Score=629, Expect=0.0]} {Smed: dd_Smed_v6_1279_0_1, dd_Smed_v6_1279_0_1, [RH, Score=695, Expect=0.0]} {RNA1509_2743, RNA1509_41659} {RNA1310_15862, RNA1509_2743, RNA1509_41659} {RNA1509_2743, RNA1509_41659, RNA815_6256.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.63 | 6.349 | 0.29750 | 0.94763 | |
RegionR2 | -0.297 | 6.349 | 0.36767 | 0.76219 | |
RegionR3 | -0.264 | 6.349 | 0.33306 | 0.87109 | |
RegionR4 | 1.013 | 6.349 | 0.00069 | 0.00780 | |
RegionR5 | 0.636 | 6.349 | 0.00862 | 0.05178 | |
RegionR6 | 0.111 | 6.349 | 0.67984 | 1.00000 | |
RegionR7 | -0.181 | 6.349 | 0.57270 | 1.00000 | |
RegionR8 | -0.389 | 6.349 | 0.32444 | 0.95723 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 0.595 | 6.349 | 0.43600 | 1.00000 | |
RegenerationR2 | 0.067 | 6.349 | 0.83071 | 0.99815 | |
RegenerationR3 | 0.614 | 6.349 | 0.06589 | 0.43171 | |
RegenerationR4 | -0.334 | 6.349 | 0.31182 | 0.75190 | |
RegenerationR5 | -0.045 | 6.349 | 0.88476 | 1.00000 | |
RegenerationR6 | 0.952 | 6.349 | 0.00281 | 0.06091 | |
RegenerationBL | 1.109 | 6.349 | 0.00030 | 0.00994 | Specific for BL: 1.109 |
RegenerationTP | 0.302 | 6.349 | 0.41173 | 0.83839 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_43846 | 3542 | 73.79 | Mlig455_054802 | Neo: - Age: - Region-enriched R4: 1.013/0.00780 Regeneration-upregulated BL: 1.109 Regeneration-enriched BL: 1.109 |
PSMC4 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_054802 {REF} {Length: 1813} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=146.8]; Proteasomal ATPase OB C-terminal domain [PF16450.7, score=46.4]; AAA+ lid domain [PF17862.3, score=37.9]; AAA domain (Cdc48 subfamily) [PF07724.16, score=33.4]; AAA domain (dynein-related subfamily) [PF07728.16, score=31.7]; AAA ATPase domain [PF13191.8, score=25.0]; AAA domain [PF13401.8, score=22.0]; AAA domain [PF13238.8, score=21.2]; Protein of unknown function (DUF815) [PF05673.15, score=20.9]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=20.6]; AAA domain [PF13521.8, score=19.4]; Magnesium chelatase, subunit ChlI [PF01078.23, score=18.7]; TIP49 P-loop domain [PF06068.15, score=18.0]} {Human: ENSG00000013275, PSMC4, proteasome 26S subunit, ATPase 4, [RH, Score=716, Expect=0.0]; ENSG00000281221, PSMC4, proteasome 26S subunit, ATPase 4, [RH, Score=716, Expect=0.0]} {Mouse: ENSMUSG00000030603, Psmc4, proteasome (prosome, macropain) 26S subunit, ATPase, 4, [RH, Score=715, Expect=0.0]} {Dmel: FBgn0028686, Rpt3, Regulatory particle triple-A ATPase 3, [RH, Score=702, Expect=0.0]} {Celegans: WBGene00004503, rpt-3, Probable 26S protease regulatory subunit 6B, [RH, Score=629, Expect=0.0]} {Smed: dd_Smed_v6_1279_0_1, dd_Smed_v6_1279_0_1, [RH, Score=695, Expect=0.0]} {RNA1509_2743, RNA1509_41659} {RNA1310_15862, RNA1509_2743, RNA1509_41659} {RNA1509_2743, RNA1509_41659, RNA815_6256.1} |
2. | MligTC455_43847 | 3526 | 73.45 | Mlig455_054896 | Neo: - Age: logFC(26M/2M)=0.475 Region-enriched R4: 1.008/0.00929 Regeneration-upregulated BL: 1.126 Regeneration-enriched BL: 1.126 |
PSMC4 | 5.985 | 1.000 | 1.000 | 0.996 | 0.996 | 1.000 | 0.993 | Mlig455_054896 {REF} {Length: 1696} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=110.1]; AAA+ lid domain [PF17862.3, score=40.2]; AAA domain (Cdc48 subfamily) [PF07724.16, score=34.5]; AAA domain (dynein-related subfamily) [PF07728.16, score=27.8]; AAA ATPase domain [PF13191.8, score=25.8]; AAA domain [PF13238.8, score=22.3]; AAA domain [PF13401.8, score=22.3]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=21.8]; AAA domain [PF13521.8, score=21.0]; Protein of unknown function (DUF815) [PF05673.15, score=20.3]; Magnesium chelatase, subunit ChlI [PF01078.23, score=20.0]; AAA domain [PF13671.8, score=19.8]; TIP49 P-loop domain [PF06068.15, score=18.1]} {Human: ENSG00000281221, PSMC4, proteasome 26S subunit, ATPase 4, [Score=373, Expect=9e-130]; ENSG00000013275, PSMC4, proteasome 26S subunit, ATPase 4, [Score=373, Expect=9e-130]} {Mouse: ENSMUSG00000030603, Psmc4, proteasome (prosome, macropain) 26S subunit, ATPase, 4, [Score=372, Expect=4e-130]} {Dmel: FBgn0028686, Rpt3, Regulatory particle triple-A ATPase 3, [Score=372, Expect=1e-129]} {Celegans: WBGene00004503, rpt-3, Probable 26S protease regulatory subunit 6B, [Score=338, Expect=1e-116]} {Smed: dd_Smed_v6_1279_0_1, dd_Smed_v6_1279_0_1, [Score=374, Expect=5e-131]} {RNA1509_9119} {RNA1310_15862} {RNA815_6256.1} |
3. | MligTC455_19667 | 1945 | 40.52 | Mlig455_048916 | Neo: Int S/G2/M Age: logFC(26M/2M)=0.226 |
METAP2 | 2.479 | - | - | - | 0.805 | 0.955 | 0.719 | Mlig455_048916 {REF} {Length: 1920} {TRANSSPLICED} {Pfam: Metallopeptidase family M24 [PF00557.26, score=151.8]} {Human: ENSG00000111142, METAP2, methionyl aminopeptidase 2, [RH, Score=580, Expect=0.0]} {Mouse: ENSMUSG00000036112, Metap2, methionine aminopeptidase 2, [RH, Score=560, Expect=0.0]} {Dmel: FBgn0283478, und, uninitiated, [RH, Score=563, Expect=0.0]} {Celegans: WBGene00003130, map-2, Methionine AminoPeptidase, [RH, Score=553, Expect=0.0]} {Smed: dd_Smed_v6_2809_0_1, dd_Smed_v6_2809_0_1, [RH, Score=561, Expect=0.0]} {RNA1509_21855, RNA1509_3506, RNA1509_35350, RNA1509_44852, RNA1509_47551, RNA1509_5949, RNA1509_6431} {RNA1310_15348, RNA1509_21855, RNA1509_3506, RNA1509_35350, RNA1509_44852, RNA1509_47551, RNA1509_5949, RNA1509_6431} {RNA1509_21855, RNA1509_3506, RNA1509_35350, RNA1509_44852, RNA1509_47551, RNA1509_5949, RNA1509_6431, RNA815_5667} |
4. | MligTC455_16709 | 1302 | 27.12 | Mlig455_029518 | Neo: - Age: - Region-enriched R3: 1.855/0.00908 |
SLC13A3 | 0.969 | - | - | - | - | 0.969 | - | Mlig455_029518 {REF} {Length: 2726} {Pfam: Sodium:sulfate symporter transmembrane region [PF00939.21, score=302.1]; Citrate transporter [PF03600.18, score=114.3]} {Human: ENSG00000158296, SLC13A3, solute carrier family 13 member 3, [Score=406, Expect=7e-134]} {Mouse: ENSMUSG00000018459, Slc13a3, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3, [Score=384, Expect=3e-125]; ENSMUSG00000029700, Slc13a1, solute carrier family 13 (sodium/sulfate symporters), member 1, [Score=367, Expect=8e-119]; ENSMUSG00000020805, Slc13a5, solute carrier family 13 (sodium-dependent citrate transporter), member 5, [Score=366, Expect=1e-118]; ENSMUSG00000001095, Slc13a2, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, [Score=366, Expect=1e-118]; ENSMUSG00000029843, Slc13a4, solute carrier family 13 (sodium/sulfate symporters), member 4, [Score=365, Expect=5e-118]} {Dmel: FBgn0036816, Indy, I'm not dead yet, [Score=281, Expect=1e-86]} {Celegans: WBGene00003517, nac-1, Sodium-dependent low-affinity dicarboxylate transporter 1, [Score=317, Expect=7e-100]} {Smed: dd_Smed_v6_12964_0_8, dd_Smed_v6_12964_0_8, [Score=360, Expect=6e-117]} {RNA1509_9551} {RNA1310_8761.2} {RNA815_3645} |
5. | MligTC455_33893 | 2159 | 44.99 | Mlig455_048120 | Neo: - Age: - Region-enriched R5: 1.314/0.00000 |
SHMT2 | 0.957 | - | - | - | - | 0.957 | - | Mlig455_048120 {REF} {Length: 2300} {TRANSSPLICED} {Pfam: Serine hydroxymethyltransferase [PF00464.21, score=623.4]} {Human: ENSG00000182199, SHMT2, serine hydroxymethyltransferase 2, [Score=595, Expect=0.0]} {Mouse: ENSMUSG00000020534, Shmt1, serine hydroxymethyltransferase 1 (soluble), [RH, Score=562, Expect=0.0]} {Dmel: FBgn0029823, Shmt, Serine hydroxymethyl transferase, [RH, Score=576, Expect=0.0]} {Celegans: WBGene00003214, mel-32, Serine hydroxymethyltransferase, [RH, Score=589, Expect=0.0]} {Smed: dd_Smed_v6_2312_0_1, dd_Smed_v6_2312_0_1, [RH, Score=588, Expect=0.0]} {RNA1509_2637, RNA1509_8192} {RNA1310_8717.2, RNA1509_2637, RNA1509_8192} {RNA1509_2637, RNA1509_8192, RNA815_3601} |
6. | MligTC455_44116 | 15886 | 330.96 | Mlig455_070259 | Neo: - Age: logFC(26M/2M)=-0.821 Region-enriched R3: 1.626/0.01191 |
BHMT | 0.954 | - | - | - | - | 0.954 | - | Mlig455_070259 {REF} {Length: 1926} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=168.1]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=562, Expect=0.0]} {Mouse: ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=570, Expect=0.0]; ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=570, Expect=0.0]} {Celegans: WBGene00010988, metr-1, Probable methionine synthase, [Score=52.4, Expect=5e-07]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=578, Expect=0.0]} {RNA1509_1011, RNA1509_1309, RNA1509_300, RNA1509_6942} {RNA1310_16129.1, RNA1509_1011, RNA1509_1309, RNA1509_300, RNA1509_6942} {RNA1509_1011, RNA1509_1309, RNA1509_300, RNA1509_6942, RNA815_5900.1} |
7. | MligTC455_32739 | 3488 | 72.67 | Mlig455_000131 | Neo: Neoblast, stringent Age: logFC(26M/2M)=0.180 Region-enriched R5: 1.541/0.00001 Regeneration-upregulated BL: 1.860 Regeneration-enriched BL: 1.860 |
RRM1 | 0.951 | - | - | - | - | 0.951 | - | Mlig455_000131 {REF} {Length: 3338} {Pfam: Ribonucleotide reductase, barrel domain [PF02867.17, score=612.4]; Ribonucleotide reductase, all-alpha domain [PF00317.23, score=78.9]; ATP cone domain [PF03477.18, score=63.3]} {Human: ENSG00000167325, RRM1, ribonucleotide reductase catalytic subunit M1, [RH, Score=1181, Expect=0.0]} {Mouse: ENSMUSG00000030978, Rrm1, ribonucleotide reductase M1, [RH, Score=1188, Expect=0.0]} {Dmel: FBgn0011703, RnrL, Ribonucleoside diphosphate reductase large subunit, [RH, Score=1140, Expect=0.0]} {Celegans: WBGene00004391, rnr-1, Ribonucleoside-diphosphate reductase large subunit, [RH, Score=1118, Expect=0.0]} {Smed: dd_Smed_v6_1651_0_1, dd_Smed_v6_1651_0_1, [RH, Score=1077, Expect=0.0]} {RNA1509_1369, RNA1509_15599, RNA1509_45206} {RNA1310_3739.1, RNA1509_1369, RNA1509_15599, RNA1509_45206} {RNA1509_1369, RNA1509_15599, RNA1509_45206, RNA815_1323} |
8. | MligTC455_16708 | 1126 | 23.47 | Mlig455_029498 | Neo: - Age: Down-Down-Down, logFC(26M/2M)=-0.797 Region-enriched R4: 1.447/0.01642 |
SLC13A3 | 0.95 | - | - | - | - | 0.950 | - | Mlig455_029498 {REF} {Length: 2725} {Pfam: Sodium:sulfate symporter transmembrane region [PF00939.21, score=288.8]; Citrate transporter [PF03600.18, score=115.2]} {Human: ENSG00000158296, SLC13A3, solute carrier family 13 member 3, [Score=405, Expect=1e-133]} {Mouse: ENSMUSG00000018459, Slc13a3, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3, [Score=381, Expect=2e-124]; ENSMUSG00000001095, Slc13a2, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, [Score=366, Expect=1e-118]; ENSMUSG00000029700, Slc13a1, solute carrier family 13 (sodium/sulfate symporters), member 1, [Score=366, Expect=2e-118]; ENSMUSG00000029843, Slc13a4, solute carrier family 13 (sodium/sulfate symporters), member 4, [Score=364, Expect=2e-117]; ENSMUSG00000020805, Slc13a5, solute carrier family 13 (sodium-dependent citrate transporter), member 5, [Score=364, Expect=6e-118]} {Dmel: FBgn0036816, Indy, I'm not dead yet, [Score=276, Expect=2e-84]} {Celegans: WBGene00003517, nac-1, Sodium-dependent low-affinity dicarboxylate transporter 1, [Score=316, Expect=1e-99]} {Smed: dd_Smed_v6_12964_0_8, dd_Smed_v6_12964_0_8, [Score=360, Expect=6e-117]} {RNA1509_9551} {RNA1310_8761.2, RNA1509_9551} {RNA1509_9551, RNA815_3645} |